ag 1879 has been researched along with Carcinoma, Hepatocellular in 3 studies
3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cotreatment of several hepatoma cell lines with the Src inhibitor PP2 potently sensitized these cells to TRAIL and CD95, dramatically decreasing effective doses of TRAIL to as low as 1 ng/ml." | 1.34 | P60-c-src suppresses apoptosis through inhibition of caspase 8 activation in hepatoma cells, but not in primary hepatocytes. ( Bruns, C; Camaj, P; De Toni, EN; Eichhorst, ST; Gerbes, AL; Göke, B; Kuntzen, C; Mucha, SR; Sonuc, N; Thasler, WE, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, SZ | 1 |
| Zhang, LD | 1 |
| Zhang, Y | 1 |
| Xiong, Y | 1 |
| Zhang, YJ | 1 |
| Li, HL | 1 |
| Li, XW | 1 |
| Dong, JH | 1 |
| Lin, CY | 1 |
| Lin, CJ | 1 |
| Chen, KH | 1 |
| Wu, JC | 1 |
| Huang, SH | 1 |
| Wang, SM | 1 |
| De Toni, EN | 1 |
| Kuntzen, C | 1 |
| Gerbes, AL | 1 |
| Thasler, WE | 1 |
| Sonuc, N | 1 |
| Mucha, SR | 1 |
| Camaj, P | 1 |
| Bruns, C | 1 |
| Göke, B | 1 |
| Eichhorst, ST | 1 |
3 other studies available for ag 1879 and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
HBx protein induces EMT through c-Src activation in SMMC-7721 hepatoma cell line.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Epithelium; Hepatitis B virus; Humans; Liver Neoplasms; | 2009 |
Macrophage activation increases the invasive properties of hepatoma cells by destabilization of the adherens junction.
Topics: Adherens Junctions; Animals; beta Catenin; Cadherins; Carcinoma, Hepatocellular; Cell Movement; Cult | 2006 |
P60-c-src suppresses apoptosis through inhibition of caspase 8 activation in hepatoma cells, but not in primary hepatocytes.
Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 8; Caspase Inhibitors; Cell Cycle; Cell Line; Drug Syn | 2007 |