ag-1296 has been researched along with Wilms Tumor in 1 studies
6,7-dimethoxy-3-phenylquinoxaline: ATP-competitive inhibitor of receptor kinase
Wilms Tumor: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors studied the effect of genistein (broad-spectrum GFR-TK inhibitor), AG1478 (EGFR-specific GFR-TK inhibitor), and AG1295 (PDGFR-specific GFR-TK inhibitor) on proliferation and colonigenic growth of rhabdoid tumor of the kidney and Wilms' tumor cell lines: G-401 and SK-NEP-1, respectively." | 3.70 | Receptor tyrosine kinase inhibition suppresses growth of pediatric renal tumor cells in vitro. ( DeMattia, JA; Khoshyomn, S; Naraghi, S; Vane, DW, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naraghi, S | 1 |
| Khoshyomn, S | 1 |
| DeMattia, JA | 1 |
| Vane, DW | 1 |
1 other study available for ag-1296 and Wilms Tumor
| Article | Year |
|---|---|
Receptor tyrosine kinase inhibition suppresses growth of pediatric renal tumor cells in vitro.
Topics: Adult; Cell Division; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Genistein; Humans | 2000 |