ag-1296 has been researched along with Disease Models, Animal in 7 studies
6,7-dimethoxy-3-phenylquinoxaline: ATP-competitive inhibitor of receptor kinase
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As the glial scar was a mechanical barrier to regeneration, inhibitory molecules in the forming scar and methods to overcome them have suggested molecular modification strategies to allow neuronal growth and functional regeneration." | 1.46 | Inhibition of platelet-derived growth factor receptor β reduces reactive glia and scar formation after traumatic brain injury in mice. ( Fang, Y; Li, D; Li, HP; Liu, N; Pei, D; Wang, QB; Xie, L; Yan, H, 2017) |
| "Corneal neovascularization was induced in wild-type BALB/C mice by removal of the corneal and limbal epithelia." | 1.37 | Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves the antiangiogenic efficacy for advanced stage mouse corneal neovascularization. ( Chaoran, Z; Gezhi, X; Zhirong, L, 2011) |
| "Corneal neovascularization was induced in C57 mice by removal of the limbal epithelium." | 1.33 | The role of PDGF receptor inhibitors and PI3-kinase signaling in the pathogenesis of corneal neovascularization. ( Dell, S; Joussen, AM; Kociok, N; Müther, P; Peters, S, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Pattamatta, U | 1 |
| Willcox, M | 1 |
| Stapleton, F | 1 |
| Cole, N | 1 |
| Garrett, Q | 1 |
| Gu, M | 1 |
| Donato, M | 1 |
| Guo, M | 1 |
| Wary, N | 1 |
| Miao, Y | 1 |
| Mao, S | 1 |
| Saito, T | 1 |
| Otsuki, S | 1 |
| Wang, L | 1 |
| Harper, RL | 1 |
| Sa, S | 1 |
| Khatri, P | 1 |
| Rabinovitch, M | 1 |
| Pei, D | 1 |
| Liu, N | 1 |
| Li, D | 1 |
| Yan, H | 1 |
| Wang, QB | 1 |
| Fang, Y | 1 |
| Xie, L | 1 |
| Li, HP | 1 |
| Chaoran, Z | 1 |
| Zhirong, L | 1 |
| Gezhi, X | 1 |
| Watanabe, T | 1 |
| Ohtani, T | 1 |
| Aihara, M | 1 |
| Ishiuchi, S | 1 |
| Dell, S | 1 |
| Peters, S | 1 |
| Müther, P | 1 |
| Kociok, N | 1 |
| Joussen, AM | 1 |
7 other studies available for ag-1296 and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Bovine lactoferrin stimulates human corneal epithelial alkali wound healing in vitro.
Topics: Animals; Burns, Chemical; Cell Movement; Cell Proliferation; Cells, Cultured; Cytokines; Disease Mod | 2009 |
iPSC-endothelial cell phenotypic drug screening and in silico analyses identify tyrphostin-AG1296 for pulmonary arterial hypertension.
Topics: Animals; Cell Proliferation; Computer Simulation; Cyclic AMP Response Element-Binding Protein; Disea | 2021 |
Inhibition of platelet-derived growth factor receptor β reduces reactive glia and scar formation after traumatic brain injury in mice.
Topics: Animals; Blotting, Western; Brain Injuries, Traumatic; Cicatrix; Disease Models, Animal; Fluorescent | 2017 |
Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves the antiangiogenic efficacy for advanced stage mouse corneal neovascularization.
Topics: Angiogenesis Inhibitors; Animals; Corneal Neovascularization; Disease Models, Animal; Dose-Response | 2011 |
Enhanced antitumor effect of YM872 and AG1296 combination treatment on human glioblastoma xenograft models.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Model | 2013 |
The role of PDGF receptor inhibitors and PI3-kinase signaling in the pathogenesis of corneal neovascularization.
Topics: Androstadienes; Angiopoietin-1; Angiopoietin-2; Animals; Chromones; Cornea; Corneal Neovascularizati | 2006 |