Page last updated: 2024-10-22

ag-1296 and Bone Neoplasms

ag-1296 has been researched along with Bone Neoplasms in 2 studies

6,7-dimethoxy-3-phenylquinoxaline: ATP-competitive inhibitor of receptor kinase

Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.

Research Excerpts

ExcerptRelevanceReference
"We report that prostate cancer cells that metastasize to the skeleton respond to human bone marrow with a robust stimulation of the phosphatidylinositol 3-kinase/Akt pathway, whereas prostate cells that lack bone-metastatic potential respond negligibly."1.34Human bone marrow activates the Akt pathway in metastatic prostate cells through transactivation of the alpha-platelet-derived growth factor receptor. ( Dolloff, NG; Fatatis, A; Loizos, N; Russell, MR, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uren, A1
Merchant, MS1
Sun, CJ1
Vitolo, MI1
Sun, Y1
Tsokos, M1
Illei, PB1
Ladanyi, M1
Passaniti, A1
Mackall, C1
Toretsky, JA1
Dolloff, NG1
Russell, MR1
Loizos, N1
Fatatis, A1

Other Studies

2 other studies available for ag-1296 and Bone Neoplasms

ArticleYear
Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells.
    Oncogene, 2003, Apr-17, Volume: 22, Issue:15

    Topics: Animals; Becaplermin; Bone Neoplasms; Cell Division; Chemotaxis; Class Ib Phosphatidylinositol 3-Kin

2003
Human bone marrow activates the Akt pathway in metastatic prostate cells through transactivation of the alpha-platelet-derived growth factor receptor.
    Cancer research, 2007, Jan-15, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Animals; Antibodies, Monoclonal; Antibody Specificity; Becaplermin; Bone Marrow;

2007