ag-1296 has been researched along with Bone Neoplasms in 2 studies
6,7-dimethoxy-3-phenylquinoxaline: ATP-competitive inhibitor of receptor kinase
Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report that prostate cancer cells that metastasize to the skeleton respond to human bone marrow with a robust stimulation of the phosphatidylinositol 3-kinase/Akt pathway, whereas prostate cells that lack bone-metastatic potential respond negligibly." | 1.34 | Human bone marrow activates the Akt pathway in metastatic prostate cells through transactivation of the alpha-platelet-derived growth factor receptor. ( Dolloff, NG; Fatatis, A; Loizos, N; Russell, MR, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uren, A | 1 |
| Merchant, MS | 1 |
| Sun, CJ | 1 |
| Vitolo, MI | 1 |
| Sun, Y | 1 |
| Tsokos, M | 1 |
| Illei, PB | 1 |
| Ladanyi, M | 1 |
| Passaniti, A | 1 |
| Mackall, C | 1 |
| Toretsky, JA | 1 |
| Dolloff, NG | 1 |
| Russell, MR | 1 |
| Loizos, N | 1 |
| Fatatis, A | 1 |
2 other studies available for ag-1296 and Bone Neoplasms
| Article | Year |
|---|---|
Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells.
Topics: Animals; Becaplermin; Bone Neoplasms; Cell Division; Chemotaxis; Class Ib Phosphatidylinositol 3-Kin | 2003 |
Human bone marrow activates the Akt pathway in metastatic prostate cells through transactivation of the alpha-platelet-derived growth factor receptor.
Topics: Adolescent; Adult; Animals; Antibodies, Monoclonal; Antibody Specificity; Becaplermin; Bone Marrow; | 2007 |