Page last updated: 2024-08-21

aflatoxin b1 and Liver Neoplasms

aflatoxin b1 has been researched along with Liver Neoplasms in 372 studies

Research

Studies (372)

TimeframeStudies, this research(%)All Research%
pre-199073 (19.62)18.7374
1990's95 (25.54)18.2507
2000's96 (25.81)29.6817
2010's82 (22.04)24.3611
2020's26 (6.99)2.80

Authors

AuthorsStudies
Santella, RM; Shen, J; Siegel, A; Wu, HC1
Kang, Q; Liang, X; Liu, Q; Wang, W; Wang, Z1
Cao, D; Cao, W; Yang, K; Yu, P1
Ali, FI; Ilyas, R; Khan, R; Mustufa, MA; Naqvi, SNUH; Zia, Z1
Abdelrady, YA; Abo-Hiemad, HM; Mohamed, MA; Nassar, AY; Sayed, AM; Shatat, AR; Soliman, M1
Alvarez, CS; Brochier, M; Dean, M; Groopman, J; Higson, H; Jones, K; Lajous, M; Lino-Silva, LS; McGlynn, KA; Melchor-Ruan, J; Mohar, A; Romero-Martínez, M; Santiago-Ruiz, L; Smith, JW; Villalpando, S; Wang, M; Wu, D; Xie, Y1
D'Errico, A; Fornari, F; Giovannini, C; Gnudi, F; Gramantieri, L; Mandrioli, D; Piscaglia, F; Suzzi, F; Tovoli, F; Vasuri, F; Vornoli, A1
Adesogan, A; Havelaar, A; Saha Turna, N; Wu, F1
Chhonker, SK; Koiri, RK; Rawat, D1
Belpoggi, F; Gnudi, F; Mandrioli, D; Manservisi, F; Sgargi, D; Tibaldi, E; Tovoli, F; Vornoli, A1
Civil, O; Şen, L1
Abdo, A; Afihene, M; Cunha, L; Desalegn, H; Dusheiko, G; Jonas, E; Kassianides, C; Katsidzira, L; Kramvis, A; Lam, P; Lesi, OA; Micah, EA; Musabeyezu, E; Ndow, G; Nnabuchi, CV; Ocama, P; Okeke, E; Rwegasha, J; Shewaye, AB; Some, FF; Sonderup, MW; Spearman, CW; Tzeuton, C1
Akriviadis, E; Chatziioannou, A; Chourmouzi, D; Dedes, I; Giannakopoulou, L; Kalogeropoulou, L; Liava, C; Moumtzouoglou, A; Papadopoulou, E; Potsi, S; Sinakos, E; Stergioulas, L1
Clausen, N; Elgart, B; Foley, JF; Gerrish, K; Gladwell, W; Mav, D; Merrick, BA; Phadke, D; Shah, R; Tripodi, I; Weick, M1
Andric, N; Fa Nedeljkovic, S; Milošević, N; Samardzija Nenadov, D; Škrbić, S; Stanic, B; Sukur, N1
Fathy, SA; Ghareeb, DA; Hamdy, GM; Khedr, SM1
Abdel-Mageed, W; Abdel-Rahman, MH; Ezzat, S; Kohla, M; Mosbeh, A; Sultan, MM1
Hu, Y; Lan, H; Lei, Y; Liang, L; Lv, Y; Wang, X; Wei, S; Zhai, H; Zhang, S1
Jin, J; Kesari, S; Kouznetsova, VL; Tsigelny, IF1
Liu, M; Tang, D; Wang, B; Wang, Z; Zhang, Z1
Herzog, N; Kammerer, S; Katzenberger, N; Küpper, JH; Pfeifer, N; Schulz, C; Steinbrecht, S1
Fu, W; He, L; Huang, Y; Luo, J; Lv, C; Qiu, Z; Shu, W; Tan, Y; Wang, J; Wang, L; Zeng, H; Zheng, C1
Bielenberg, DR; Deng, J; Fishbein, A; Gartung, A; Hallisey, VM; Hammock, BD; Huang, S; Hwang, SH; Kieran, MW; Panigrahy, D; Verheul, SML; Wang, W; Wang, Y; Yang, H; Yang, J1
Cvelbar, U; Filipič, M; Hojnik, N; Javornik, U; Modic, M; Plavec, J; Walsh, JL; Žegura, B; Žigon, D1
Fan, T; Ma, W; Xie, Y1
He, K; Liu, F; Wang, H; Wang, S; Wang, X; Yang, X; Zhang, X1
Cai, J; He, H; Jiao, Y; Li, M; Liang, J; Liu, M; Ma, Y; Qu, C; Wang, X; Wei, Z; Zeng, Y; Zhang, Y; Zhu, Q1
Chen, JA; Feng, X; He, L; Huang, Y; Lin, H; Liu, W; Luo, J; Luo, Y; Pu, C; Qiu, Z; Shu, W; Tan, Y; Tian, Y; Wang, J; Wang, L; Wu, L; Xiao, G; Yang, X; Zeng, H; Zhang, R; Zheng, C1
Abedi-Ardekani, B; Ardin, M; Boot, A; Heguy, A; Hollstein, M; Huang, MN; Jusakul, A; Myint, SS; Ng, AWT; Olivier, M; Othman, R; Poon, SL; Rozen, SG; Sabapathy, K; Tan, P; Teh, BT; Teoh, WW; Villar, S; Yu, W; Zavadil, J1
Li, LQ; Ma, L; Qi, LN; Qin, HG; Wang, YY; Xiang, BD; Xiang, X; You, XM; Zhong, JH1
He, L; Li, D; Liu, L; Liu, W; Shu, W; Tan, Y; Wang, J; Wang, L; Zhao, X; Zheng, C1
Åkesson, A; Eneroth, H; Leander, K; Nilsson Sommar, J; Wallin, S1
Egner, PA; Freedman, ND; Groopman, JD; Guallar, E; Kroker-Lobos, MF; Lazo, M; McGlynn, KA; Ramirez-Zea, M; Rivera-Andrade, A; Smith, JW; Torres, O; Wedemeyer, H1
Maurya, BK; Trigun, SK1
Khotimah, K; Nugraha, A; Rietjens, IMCM1
Becker, RA; Moore, MM; Pottenger, LH; Schoeny, RS; White, K1
Amougou Atsama, M; Atangana, PJA; Bekondi, C; Béré, A; Camengo-Police, SM; Komas, NP; Marchio, A; Njouom, R; Noah Noah, D; Pineau, P1
Chen, XP; Chen, Y; Liu, KC; Mo, PL; Wang, J; Wei, YJ; Zhang, L; Zhang, ZG; Zhang, ZW1
Amorim, RP; Cardoso, MV; de Souza Furtado, KM; Espíndola, KMM; Ferreira, RG; Monteiro, MC1
Rushing, BR; Selim, MI1
Engin, A; Engin, AB1
Gao, Y; Wang, C; Xiao, P; Xu, H; Zhang, Y1
Li, R; Liang, X; Liu, M; Su, M; Zhou, R1
Huang, XY; Liu, M; Long, XD; Ma, Y; Mo, XQ; Wang, C; Wei, ZH; Xia, Q; Xue, F; Yao, JG; Zeng, LX; Zhai, B; Zhang, JJ; Zhao, D1
Dejean, A; Generalov, MI; Granov, DA; Kalinina, O; Marchio, A; Pineau, P; Rebbani, K; Tarkova, AB; Urbanskii, AI1
Chaudhary, H; Jena, PK; Seshadri, S1
Bohacek, R; Buchmann, S; Edelbauer, L; Ferk, F; Grasl-Kraupp, B; Huber, WW; Knasmüller, S; Mišík, M; Speer, K1
Dhanda, S; Moudgil, V; Redhu, D; Singh, J1
Chen, Z; Ji, J; Li, J; Wang, H; Yang, L1
Bai, T; Chen, YY; Chen, ZH; Han, ZG; Li, LQ; Li, S; Liu, TW; Liu, ZM; Mo, ZN; O'Brien, SJ; Peng, MH; Peng, T; Qi, LN; Qin, X; Santella, RM; Winkler, CA; Xiang, BD; Xiao, KY1
Burgers, PM; Li, L; Lin, YC; Lloyd, RS; Makarova, AV; Stone, MP2
Chen, S; Ding, ZB; Fan, J; Huang, XW; Peng, YF; Qiu, SJ; Ren, N; Shen, YH; Shi, YH; Yang, GH; Yi, Y; Zhou, J1
Bai, T; Chen, YY; Chen, ZS; De Xiang, B; Han, ZG; Li, LQ; Peng, T; Qi, LN; Wu, FX1
Feng, Y; Guo, Z; Lian, J; Srinivas, S; Wang, S; Yang, W; Zhong, H; Zhuang, Z1
Li, SQ; Luo, L; Lv, J; Wang, Q; Yu, YQ1
Abdullah, A; Chin, CK; Sugita-Konishi, Y1
Huang, XY; Liu, YX; Long, XD; Ma, Y; Wang, C; Xi, ZF; Xia, Q; Xing, TY; Yao, JG1
Abdussalam, FA; Adeleye, AO; Ajiboye, TO; Balogun, A; Iliasu, GA; Ojewuyi, OB; Yakubu, MT1
Chen, J; He, K; Lai, H; Lin, Y; Liu, C; Mo, X; Xiao, J; Yang, Y1
Ajiboye, TO; Oladiji, AT; Yakubu, MT1
Nault, JC1
Huang, XY; Long, XD; Yao, JG1
De Meulenaer, B; De Saeger, S; Jacxsens, L; Kolsteren, P; Lachat, C; Walpita, CN; Yogendrarajah, P1
Massey, TE; Mulder, JE; Turner, PV1
Li, C; Li, T; Liu, Y; Sun, Y; Wang, T; Zhang, J1
Goh, LK; Sabapathy, K; Teoh, WW; Tong, WM; Vijayaraghavan, A; Xie, M; Yaligar, J1
Huang, XY; Liao, P; Long, XD; Ma, Y; Tang, YJ; Xia, Q; Yao, JG1
Asiki, G; Kaleebu, P; Kang, MS; Lutalo, T; Muwanika, R; Nalugoda, F; Newton, R; Nkurunziza, P; Nkwata, A; Qian, G; Seeley, J; Serwadda, D; Song, X; Ssempebwa, J; Tang, L; Wang, JS; William, JH; Xue, K1
Gao, J; Huang, K; Luo, Y; Xu, W; Zhang, B; Zhu, L1
Beland, FA; Marrone, AK; Pogribny, IP; Tryndyak, V1
Huang, BC; Huang, XY; Long, XD; Ma, Y; Xia, Q; Yao, JG1
Arumugam, P; Ju, H; Shim, Y; Song, JM1
Bekers, O; Claessen, SM; de Kok, TM; Jennen, DG; Kleinjans, JC; Rieswijk, L; Theunissen, DH; van Breda, SG; van Herwijnen, M1
Fu, R; Wang, S; Yang, C; Zhuang, Z1
Bai, XC; Chen, KH; Chen, ZX; Gao, T; Jia, CH; Lan, J; Pan, D; Pan, JF; Wei, HM1
He, J; Jiang, C; Lin, J; Ou, C; Shi, J; Sun, F; Sun, X1
Brimer, L; Dalsgaard, A; Huong, BTM; Tuan, DH; Tuyen, LD1
Amin, S; Choi, B; Desai, D; Hu, Y; Lee, HW; Mehta, M; Tang, MS; Wang, HT; Weng, MW; Zheng, Y1
Gong, YY; Groopman, JD; Kieszak, SM; McCoy, LF; Powers, CD; Rogers, HS; Schleicher, RL; Scholl, PF; Sutcliffe, AE; Wild, CP1
Baumgartner, KJ; Dinkova-Kostova, AT; Egner, PA; Gribble, GW; Groopman, JD; Honda, T; Kensler, TW; Liby, K; Risingsong, R; Roebuck, BD; Royce, DB; Sporn, MB; Stephenson, KK; Sundararajan, C; Williams, CR; Yates, MS; Yore, MM; Yoshizawa, H1
Benninghoff, AD; Carpenter, HM; Hendricks, JD; Orner, GA; Pereira, CB; Tilton, SC; Williams, DE1
Baumgartner, KJ; Bodreddigari, S; Egner, PA; Friesen, MD; Groopman, JD; Johnson, DN; Kensler, TW; Roebuck, BD; Scholl, PF; Sutter, CH; Sutter, TR; Ware, NM1
Fabregat, I1
Ahsan, H; Chen, CJ; Chen, SY; Santella, RM; Tsai, WY; Wang, LY; Wang, Q; Wu, HC; Yang, HI2
Ellis, EM1
Li, FQ; Li, YW; Luo, XY; Wang, YR1
Ji, L; Yu, H1
Gasbarrini, A; Pani, G; Petersen, BE; Piscaglia, AC; Shupe, TD; Tesori, V1
Besaratinia, A; Hainaut, P; Kim, SI; Pfeifer, GP1
Chen, T; Heflich, RH; Mei, N; Moore, MM1
Aguilar-Melero, P; Barrera, P; Bello, RI; de la Mata, M; Ferrín, G; González, R; González-Rubio, S; Hidalgo, AB; Linares, CI; Marchal, T; Muntané, J; Nakayama, KI; Ranchal, I1
Crawford, D; Egner, PA; Ilic, Z; Sell, S; Vakharia, D1
Ban, FZ; Huang, BC; Huang, YZ; Long, XD; Ma, Y; Yao, JG; Zhou, YF1
Abdel-Wahhab, MA; El-Kady, AA; El-Nekeety, AA; Hassan, NS; Khadrawy, YA; Mannaa, FA; Mohamed, SR; Sharaf, HA1
Angeli, JP; Barbosa, F; Barcelos, GR; Mantovani, MS; Nersesyan, A; Serpeloni, JM1
Drouin, R; Lacoste, S; Rochette, PJ1
Kew, MC2
Abedi-Ardekani, B; Caron de Fromentel, C; Chemin, IA; Egevad, LA; Galy, O; Gouas, DA; Hainaut, PL; Hantz, O; Hautefeuille, AH; Legros, PC; Ortiz-Cuaran, SL; Shi, H; Szymanska, KJ; Wiman, KG1
Abdou, E; Boismenu, D; Hamel, N; Kearney, RE; Laboissière, S; Lanoix, J; Paiement, J; Roy, L; Taheri, M; Thibault, G1
Qian, G; Su, J; Tang, L; Wang, JS; Xu, L1
Fu, GH; Long, XD; Ma, AM; Ma, Y; Zhou, YF1
Azeez, OI; Oyagbemi, AA; Saba, AB1
Cunningham, K; Donnelly, KC; Guerra, F; Johnson, NM; Kaufman, L; Marroquin-Cardona, A; Phillips, TD; Qian, G; Robinson, A; Rodriguez, M; Tietze, D; Wang, JS; Williams, JH; Wittmer, J; Xu, L1
Akano, A; Bah, E; Hainaut, P; Kirk, GD; Lesi, OA; Mendy, M; Umoh, NJ; Whittle, H1
Hu, X; Su, J; Sun, G; Tang, L; Wang, JS; Wang, S; Xie, Y; Zhang, H; Zhang, Y1
Gursoy-Yuzugullu, O; Ozturk, M; Yilmaz, M; Yuzugullu, H1
Belanger, CL; Bouhenguel, JT; Croy, RG; Egner, PA; Essigmann, JM; Groopman, JD; Trudel, LJ; Wattanawaraporn, R; Wogan, GN; Woo, LL1
Callegari, E; Elamin, BK; Gramantieri, L; Negrini, M; Sabbioni, S1
Egashira, A; Harimoto, N; Kajiyama, K; Maehara, Y; Shirabe, K; Taguchi, K; Taketomi, A; Toshima, T; Uchiyama, H; Yoshizumi, T1
Asim, M; Kar, P; Sarma, MP; Thayumanavan, L1
Aggarwal, PK; Behare, PV; Gautam, SK; Grover, CR; Kumar, A; Kumar, M; Nagpal, R; Verma, V1
Feng, Y; Huang, H; Li, HX; Li, P; Mao, QS; Rui, L; Sha, ZY; Xue, WJ1
El-Serag, HB1
Ding, C; Qin, H; Yu, H1
Eaton, DL; Gross-Steinmeyer, K1
Bah, E; Chemin, I; Ferro, G; Friesen, MD; Gouas, DA; Groopman, J; Hainaut, P; Kirk, GD; Legros, P; Lesi, OA; Mendy, M; Ortiz-Cuaran, S; Villar, S1
Hua, H; Jiang, Y; Kong, Q; Luo, T; Ma, Y1
Asim, M; Kar, P; Sarma, MP1
Chen, J; Chen, T; Gail, MH; Hsia, CC; Huang, F; Liu, G; Lu, J; Lu, L; Lu, P; Ni, Z; Park, JH; Qu, C; Sun, Z; Thorgeirsson, SS; Wang, N; Wu, Y; Wu, Z; Xu, L; Zhan, Q; Zhang, Q; Zhu, Y1
Huang, XY; Liu, M; Long, XD; Ma, Y; Wei, ZH; Xia, Q; Xue, F; Yao, JG; Zeng, Z; Zhai, B; Zhang, JJ1
Shuker, DE1
Ahsan, H; Chen, CJ; Chen, SY; Chen, Y; Lee, PH; Lunn, RM; Santella, RM; Wang, LY; Zhang, YJ1
Groopman, JD; He, X; Jackson, PE; Kuang, SY; Qian, GS1
Aly, SE1
Chen, CJ; Santella, RM; Sun, CA; Wang, LY; Wu, DM; You, SL1
Ahsan, H; Chen, CJ; Chen, Y; Lee, PH; Lunn, RM; Santella, RM; Zhang, YJ1
Chen, GC; Cheng, G; Harada, K; Huang, XE; Koide, T; Mizokami, M; Oda, H; Ohno, T; Sueoka, E; Tashiro, F; Tokudome, S; Ueno, Y; Xiang, J; Yu, SZ1
Jun, HS; Kim, SE; Sung, MK1
Buetow, KH; Evans, AA; Hunter, K; LeVoyer, T; London, WT; McGlynn, KA; Michielli, RA; Roush, J; Shen, FM; Wise, P1
Au, WW; Salama, SA1
Ban, KC; Cao, J; Gu, JR; Li, Y; Luo, D; Ou, C; Qin, LL; Qiu, XK; Su, JJ; Wan, DF; Yang, C; Yue, HF; Zhang, LS1
Sell, S; Shupe, T1
Nayak, NC1
Chen Ban, K; Fong Seow, H; Krishnan, R; Singh, H1
Cecere, A; Gattoni, A; Marotta, F; Vangieri, B1
Gopalan-Kriczky, P; Kimura, M; Lehmann, K; Lotlikar, PD1
Brockmöller, J; Hustert, E; Kirk, G; Mendy, M; Pedersen, B; Turner, PC; Whittle, HC; Wild, CP; Wojnowski, L1
Alessi, M; Bedard, LL; Davey, S; Massey, TE1
Ahsan, H; Chen, CJ; Chen, SY; Chen, Y; Lee, PH; Lunn, RM; Santella, RM; Zhang, YJ1
Choon-Nam, O; Han-Ming, S; Le-Qun, L; Lian-Wen, W; Lu-Nam, Y; Min-Hao, P; Qiao, W; Ren-Xiang, L; Santella, RM; Tang-Wei, L; Tao, P; Xue, Q; Zhi-Ming, L; Zong-Liang, W1
Xue, KX1
Choi, EH; Chun, HS; Lee, JK; Lee, KG1
Arakawa, K; Hodkinson, J; Kew, MC; Kimbi, GC; Yu, MC1
Bailey, GS; Bayne, CJ; Corley-Smith, G; Gerwick, LG; Givan, SA; Hendricks, JD; Rosato, CS; Tilton, SC; Williams, DE1
Deng, ZL; Long, XD; Ma, Y; Wei, YP2
Gormally, E; Hainaut, P; Le Roux, E1
Das, M; Dogra, RK; Khanna, SK; Rastogi, S1
Billam, M; Kendall, RJ; McKean, C; Tang, L; Tang, M; Theodorakis, CW; Wang, JS; Wang, Z1
Galendo, D; Lee, MK; Sabapathy, K; Tong, WM; Wang, ZQ1
Agrawal, M; Ahsan, H; Chen, Y; Lee, PH; Rossner, P; Santella, RM; Wang, L; Wang, Q; Yu, MW; Zhang, YJ1
Belloir, C; Daurat, C; Le Bon, AM; Siess, MH; Singh, V1
Abdel-Hadi, AA; Abu Zikri, NB; El-Ansary, M; El-Raai, A; El-Shanawani, FM; Ismail, A1
Diallo, MS; Friesen, MD; Groopman, JD; Scholl, PF; Sutcliffe, AE; Sylla, A; Turner, PC; Wild, CP1
Bah, E; Kirk, GD; Montesano, R1
El-Nezami, HS; Juvonen, RO; Ling, W; Ma, J; Mykkänen, HM; Polychronaki, NN; Poussa, T; Salminen, EK; Salminen, SJ; Zhu, H1
Dixon, KR; Lian, M; Liu, Y; Qian, GS; Wan, SG; Yu, SZ1
Han, EH; Jeong, HG; Kang, KW; Kim, JY; Kim, SK; Oh, SJ; Pokharel, YR; Woo, ER1
Awad, AT; Habib, SL; Mostafa, MH; Said, B; Shank, RC1
Ahsan, H; Chen, CJ; Chen, SY; Santella, RM; Tsai, WY; Wang, LW; Wang, LY; Wang, Q; Wu, HC; Yang, HI1
DePinho, RA; Farazi, PA1
Aninat, C; Corlu, A; Glaise, D; Guguen-Guillouzo, C; Guillouzo, A; Morel, F1
Bailey, GS; Hendricks, JD; Orner, GA; Pereira, CB; Tilton, SC; Williams, DE1
Bailey, GS; Dashwood, RH; Egner, PA; Groopman, JD; Jubert, C; Kensler, TW; Orner, GA; Pereira, C; Roebuck, BD; Simonich, MT; Williams, DE1
Harris, CC; Hussain, SP; Schwank, J; Staib, F; Wang, XW1
Guo, Y; Kasai, H; Khan, KM; Lee, BL; Li, LQ; Liang, RX; Liu, TW; Liu, ZM; Mo, XS; Ong, CN; Peng, MH; Peng, T; Qin, Z; Santella, RM; Shen, HM; Tamae, K; Wang, KB; Wang, LW; Wang, Q; Wei, ZL; Xiao, KY; Yan, LN; Ye, XP1
Guo, Y; Li, LQ; Li, S; Liang, RX; Liu, TW; Liu, ZM; Mo, XS; Ong, CN; Peng, MH; Peng, T; Qin, X; Qin, Z; Santella, RM; Shen, HM; Wang, KB; Wang, L; Wang, Q; Wei, ZL; Xiao, KY; Yan, LN; Ye, XP1
Cao, J; Cui, J; Dai, Z; Duan, X; Kang, X; Li, Y; Liu, Y; Ou, C; Qin, X; Su, J; Yang, C; Yue, H; Zhang, Y1
Begum, VH; Sivanesan, D1
Su, H; Xiong, Y; Xu, T; Yuan, Y; Zhang, Y; Zhao, J; Zhou, F; Zhuang, SM1
Huang, YZ; Huang, ZQ; Lin, ZH; Liu, YG; Long, XD; Ma, Y; Qu, DY; Wei, NB; Zhou, SC1
Kanisawa, M1
Ding, ZR1
Garner, JV; Garner, RC; Martin, CN; Montesano, R; Ryder, RW; Sizaret, P; Tursi, F; Whittle, HC1
Bednarz, W; Zawirska, B1
Appleton, BS; Campbell, TC2
Enwonwu, CO1
Campbell, TC; Misslbeck, NG; Roe, DA1
Angsubhakorn, S; Bhamarapravati, N; Miyamoto, M; Romruen, K; Sahaphong, S; Thamavit, W1
Bismuth, H; Franco, D; Morin, J; Szekely, AM1
Babish, JG; Boyd, JN; Stoewsand, GS1
Boyd, JN; Misslbeck, N; Stoewsand, GS1
Boynton, AL; Kleine, LP; Whitfield, JF1
Lambiotte, M; Thierry, N1
Hayes, AW; Hogan, GR; Ryan, NJ; Siraj, MY; Unger, PD; Wray, BB1
Bréchot, C; Castaing, D; Franco, D; Morin, J1
Lindsay, DG; Watson, DH1
Ogbadu, GH; Onyemelukwe, GC; Salifu, A1
Huh, N; Nemoto, N; Utakoji, T1
Akintonwa, DA1
Abe, S; Nemoto, N; Sasaki, M1
Iype, PT; Kroeger-Koepke, MB; Lijinsky, W; Michejda, CJ; Reuber, MD1
Cabral, JR; Neal, GE1
Green, JA; Neal, GE1
Goldman, M; Newberne, PM; Suphakarn, VS1
Lan, LZ; Li, WG; Liu, YY; Wang, YB; Xu, YC; Ye, BF1
Dix, KM1
Chu, YY; Sun, TT1
Klaunig, JE1
Connor, M; Newberne, PM1
Ayraud, N; Dvorackova, I; Stora, C1
Green, JA; Judah, DH; Legg, RF; Metcalfe, SA; Neal, GE1
Avadhani, NG; Bhat, NK; Niranjan, BG1
Hendricks, JD; Shelton, DW; Voss, SD1
Haseman, JK; Hoel, DG; Jennrich, RI1
Farber, E1
Flörke, R; Novi, AM; Stukenkemper, M1
Zhang, FS1
Bailey, GS; Groopman, JD; Hendricks, JD; Loveland, PM; Pereira, C; Pierce, D1
Dutton, MF; McLean, M1
Liang, TJ1
Lee, HP; Li, B; Lin, Y; Ong, CN; Phang, TW; Shi, CY; Wee, A1
Ghebranious, N; Knoll, BJ; Lozano, G; Sell, S; Wu, H1
Choy, WN1
McMahon, G1
Bloodworth, BC; Chao, TC; Gunasegaram, R; Koh, TH; Lo, DS; Ng, HS1
Ozturk, M1
Blum, HE1
Yu, SZ; Zhao, N1
Baffoe-Bonnie, A; Clapper, ML; Hu, Y; Lustbader, ED; McGlynn, KA; Ofori-Adjei, D; Rosvold, EA; Wild, CP; Xia, XL; Zhou, T1
Aguilar, F; Cerutti, P; Hussain, P; Pourzand, C1
Sun, WM; Yu, S; Zhao, N1
Heck, R; Jennings, GS; Oesch, F; Steinberg, P1
McMichael, AJ1
Hammock, BD; Hinton, DE; Laurén, DJ; Parker, LM; Winder, B1
Murakami, Y1
Bell, RC; Campbell, TC; Levitsky, DA1
Tu, WS1
Abdel Gawad, HS; el-Mofty, MM; Essawy, A; Sakr, SA1
Aguilar, F; Cerutti, P; Harris, CC; Hollstein, M; Sun, T1
Henderson, CJ; Judah, DJ; Kirby, GM; Neal, GE; Srivatanakul, P; Wild, CP; Wolf, CR1
Cao, SF; Chutimataewin, S; Cova, L; Duflot, A; Mehrotra, R; Montesano, R; Prave, M; Trepo, C; Wild, CP; Yu, SZ1
Groopman, JD; Hasler, J; Junshi, C; Kensler, TW; Wild, CP; Wogan, GN1
Autrup, H; Autrup, JL; Schmidt, J1
Bleicher, F; Chutimataewin, S; Harris, CC; Hollstein, MC; Montesano, R; Srivatanakul, P; Wild, CP1
Cao, Y; Gu, JR; He, L; Li, D; Wang, NJ1
Hsieh, LL; Hsieh, TT1
Cova, L; Jansen, LA; Montesano, R; Wild, CP1
Chen, CJ; Feitelson, M; Haghighi, B; Hsieh, LL; Lee, CS; Santella, RM; Wang, LW; Yang, GY; Zhang, YJ1
Aguilar, F; Cerutti, P; Hussain, SP1
Chen, L; Hardwick, JP1
Soman, NR; Wogan, GN1
Lanoix, J; Paiement, J1
Bruijntjes-Rozier, GC; Evertz, SJ; Rompelberg, CJ; van den Heuvel, PD; Verhagen, H1
Bennett, WP; Bergasa, NV; Calderon, IE; Cawley, H; Chia, SC; DeBenedetti, VM; DiBisceglie, AM; Groopman, JD; Hansen, C; Harris, CC; Jones, EA; Munoz Espinosa, LE; Sandoval, CA; Soini, Y; Trivers, GE; Wang, JS; Welsh, JA1
Bailey, EA; Essigmann, JM; Harris, TM; Iyer, RS; Stone, MP1
Bell, DA; Chen, CJ; Chiamprasert, S; Hirvonen, A; Liaw, YF; Matin, F; Santella, RM; Wang, LW; Yu, MW1
Guengerich, FP; Johnson, WW; Shimada, T; Ueng, YF; Yamazaki, H1
Yap, I1
Chen, CJ; Liaw, YF; Lien, JP; Yu, MW1
Astorg, P; Bergès, R; Haber-Mignard, D; Siess, MH; Suschetet, M1
Buetow, K; Clapper, M; Evans, AA; Litwin, S; London, WT; McGlynn, K; Ross, E; Shen, FM; Wild, C; Zhou, T1
Alaoui-Jamali, MA; Batist, G; Cameron, RG; Fotouhi-Ardakani, N; Kew, M; Kirby, GM; Nakazawa, H; Yamasaki, H1
Groopman, JD; Scholl, P; Wang, JS1
Berges, R; Chaumontet, C; Heberden, C; Honikman-Leban, E; Krutovskikh, VA; Le Bon, AM; Martel, P; Shahin, MM; Suschetet, M; Yamasaki, H1
Ong, CN; Shen, HM1
Cote, PJ; Marion, PL; Rivkina, M; Robinson, WS; Tennant, BC1
Groopman, JD; Kensler, TW1
Gopalan-Kriczky, P; Hiruma, S; Kimura, M; Lehmann, K; Lotlikar, PD; Qin, GZ; Sato, K; Shinozuka, H1
Campbell, TC; He, Y; Parker, RS; Root, MM1
Chen, CJ; Chiang, YC; Lien, JP; Yu, MW1
Sengstag, C1
Kensler, TW1
Chen, CJ; Lee, CS; Lee, PH; Lunn, RM; Santella, RM; Tsai, WY; Wang, LY; Zhang, YJ1
Essigmann, JM; Kobertz, WR; Wang, D; Wogan, GN1
Peng, W; Yao, J; Zhou, Y1
Campbell, TC; Lange, T; Root, M1
de Oliveira, CA; Germano, PM1
Makarananda, K; Pengpan, U; Srisakulthong, M; Sriwatanakul, K; Yoovathaworn, K1
Egner, PA; Groopman, JD; He, X; Helzlsouer, KJ; Jacobson, LP; Kensler, TW; Kuang, SY; Muñoz, A; Qian, GS; Shen, X; Wang, JB; Wang, JS; Zarba, A; Zhang, BC; Zhu, YR1
Han, F; Ishikawa, T; Oda, H; Shimizu, Y; Zhu, JJ1
Chao, HK; Lin, CS; Su, TS; Tsai, TF1
Greenblatt, MS; Groopman, JD; Hoque, A; Patt, YZ; Santella, RM; Yoffe, B; Zhang, YJ1
Deng, Z; Ma, Y; Pan, L1
Babcock, G; Cornelius, J; Dingeldein, M; Mitchell, K; O'Brien, T; Talaska, G; Warshawsky, D1
Egner, PA; Groopman, JD; Kensler, TW; Li, Y; Qin, L; Roebuck, BD; Su, J; Wang, J1
Ban, KC; Lee, EH; Lee, YI; Park, US; Qin, L; Su, JJ1
Kuang, S; Lu, P; Wang, J1
Wogan, GN2
Das, GC; Lee, S; Lee, YI; Park, SM; Park, US1
Blum, HE; Moradpour, D1
Harris, CC; Hollstein, MH; Hussain, SP1
Liu, J; Ong, CN; Shen, HM; Tan, CE; Wasser, S; Yang, CF1
Bailey, EA; Currier, SS; Essigmann, JM; Smela, ME1
London, SJ; Stern, MC; Taylor, JA; Umbach, DM; Yu, MC; Zhang, ZQ1
Das, BC; Guptan, RC; Malhotra, V; Saigal, S; Sarin, SK; Thakur, V; Thyagarajan, SP1
Devereux, TR; Flake, GP; London, SJ; Stern, MC; Taylor, JA; Yu, MC; Zhang, ZQ1
Gaughan, JP; Gopalan-Kriczky, P; Hiruma, S; Lotlikar, PD; Qin, G1
Chen, CJ; Lu, SN; Santella, RM; Sun, CA; Wang, LW; Wang, LY; Wang, Q; Wu, DM; You, SL1
Dolan, PM; Egner, PA; Groopman, JD; Itoh, K; Kensler, TW; Kwak, MK; Ramos-Gomez, M; Yamamoto, M1
Kawamura, O; Li, FQ; Li, YW; Luo, XY; Yoshizawa, T1
Ahsan, H; Chen, CJ; Chen, SY; Lin, JT; Liu, TY; Santella, RM; Tsai, WY1
Balabaud, C; Bayer, J; Capron, F; Degott, C; Gressin, L; Legoix, P; Tubacher, E; Vaury, C; Yakicier, MC; Zucman-Rossi, J1
Devesa, SS; Fraumeni, JF; Hsing, AW; McGlynn, KA; Tsao, L1
Bailey, GS; Egner, PA; Gange, SJ; Groopman, JD; Helzlsouer, KJ; Jacobson, LP; Kensler, TW; Kuang, SY; Qian, GS; Wang, JB; Wu, Y; Zhang, BC; Zhang, QN; Zhu, YR1
Itsubo, M; Saito, A; Toda, G1
Okita, K1
Bammler, TK; Eaton, DL; Kelly, EJ1
Yu, S; Zhao, N; Zi, X1
Jiang, W; Lu, Q; Pan, G1
Emilsen, E; Fodstad, O; Lorico, A; Nesland, J; Rappa, G1
Bailey, G; Casto, B; Pereira, C; Ralston, S; Roebuck, B; Stoner, G1
Ide, F; Ishikawa, T; Kume, H; Nakatsuru, Y; Shimizu, Y; Takahashi, Y; Tanaka, K; Zhang, S1
Essigmann, JM; Hamm, ML; Harris, CM; Harris, TM; Henderson, PT; Smela, ME1
Speijers, G1
Castagnetta, LA; Cervello, M; Dantona, F; Giannitrapani, L; Montalto, G; Terranova, A1
Zhang, MD1
Fujimoto, Y; Hampton, LL; Luo, LD; Thorgeirsson, SS; Wirth, PJ1
Kolars, JC1
Thomas, D; Wu-Williams, AH; Zeise, L1
Liang, Y; Liu, JL; Liu, ZH; Ruan, CC; Tu, WS1
Chen, CJ; Lu, SN; Santella, RM; Zhang, YJ1
Yu, SZ1
Chen, SL; Mo, MQ1
Laver, GW; McMullen, E; Mehta, R; Stapley, R1
Bailey, G; Chang, YJ; Hendricks, J; Mangold, K; Marien, K; Mathews, C1
Ferguson, H; Hayes, MA; Kirby, GM; Kocal, T; Metcalfe, C; Stalker, M1
Chen, CJ; Feitelson, M; Haghighi, B; Lee, CS; Santella, R; Wang, LW; Yang, GY; Zhang, YJ1
Linko, P; Liu, YH; Lucier, GW; Taylor, J; Thompson, CL1
Ruan, CC1
Judah, DJ; Neal, GE; Olubuyide, IO; Riley, J1
Bonkovsky, HL1
Cullen, JM; Hong, X; Marion, PL; Newbold, JE; Sherman, GJ1
Cova, L; Jacquet, C; Lambert, V; Mehrotra, R; Montesano, R; Shirai, T; Tomatis, L; Trépo, C; Turusov, V; Wild, CP1
Harrison, DJ; Hayes, JD; May, L; Neal, GE1
Bauer-Hofmann, R; Buchmann, A; Schwarz, M; Wright, AS1
Angsubhakorn, S; Bhamarapravati, N; Get-Ngern, P; Miyamoto, M1
Kilonzo, MM; Nyandieka, HS; Wakhis, J1
Hsieh, DP1
Li, DR; Li, YD; Liu, ZH; Qin, BB; Tu, WS; Xie, CH; Yang, YZ1
Aoyama, T; Gelboin, HV; Gonzalez, FJ; Guzelian, PS; Yamano, S1
Best, SJ; Cameron, RG; Crane, TL; Farber, E; Hayes, MA; Kocal, TE; Quinn, BA; Rushmore, TH1
Castelli, D; Krebs, B; Lafaurie, M; Seralini, GE; Stora, C1
Büsser, MT; Lutz, WK1
Bechtel, DH1
Tabor, E1
Henderson, BE; Luo, S; Mo, CC; Tong, MJ; Yeh, FS; Yu, MC1
Lee, HS; Sarosi, I; Vyas, GN1
Gebhardt, R; Tanaka, T; Williams, GM1
Dvorackova, I; Garner, RC; Tursi, F1
Chang, LW; Klaunig, JE; Pereira, MA1
Maeura, Y; Tanaka, T; Williams, GM1
Fischer, G1
Baldwin, S; Parker, RS2
Mo, CC; Yeh, FS; Yen, RC1
Blum, HE; Busch, MP; Rajagopalan, MS; Vyas, GN1
Dvorackova, I; Stora, C2
Autrup, H; Seremet, T; Wakhisi, J; Wasunna, A1
Harris, CC; Sun, TT1
Boobis, AR; Collier, N; Davies, DS; Harries, GC1
Garner, RC; Montesano, R; Tursi, F; Wild, CP1
del Campo, AA; McMahon, JB; Richards, WL; Song, MK; Thorgeirsson, SS1
Hanson, L; Lee, JJ; McMahon, G; Wogan, GN1
Campbell, TC; Dunaif, GE1
Li, WG; Shou, LQ1
Hacobian, N; Ho, LL; Lotlikar, PD; Magee, PN; Prasanna, HR1
Hulbert, PB; Judah, DJ; Neal, GE; Nielsch, U1
Cole, KE; Hsu, IC; Jones, TW; Lipsky, MM; Trump, BF1
McConnell, EE; Soffritti, M1
Bailey, GS; Goeger, DE; Hendricks, JD; Pereira, C; Shelton, DW1
Groopman, JD1
Autrup, H; Wakhisi, J1
Black, JJ; Maccubbin, AE; Myers, HK; Zeigel, RF1
Lutz, WK; Marinovich, M1
Metcalfe, CD; Sonstegard, RA1

Reviews

62 review(s) available for aflatoxin b1 and Liver Neoplasms

ArticleYear
Aflatoxin B1: metabolism, toxicology, and its involvement in oxidative stress and cancer development.
    Toxicology mechanisms and methods, 2022, Volume: 32, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Hepatocellular; DNA; Humans; Liver Neoplasms; Oxidative Stress

2022
Hepatocellular carcinoma: measures to improve the outlook in sub-Saharan Africa.
    The lancet. Gastroenterology & hepatology, 2022, Volume: 7, Issue:11

    Topics: Aflatoxin B1; Africa South of the Sahara; Carcinoma, Hepatocellular; Hepatitis C; Humans; Liver Neoplasms

2022
Liver Imaging Reporting and Data System criteria for the diagnosis of hepatocellular carcinoma in clinical practice: A pictorial minireview.
    World journal of gastroenterology, 2022, Aug-28, Volume: 28, Issue:32

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Contrast Media; Humans; Liver Neoplasms; Magnetic Resonance Imaging; Retrospective Studies; Sensitivity and Specificity

2022
Synergism in actions of HBV with aflatoxin in cancer development.
    Toxicology, 2023, Volume: 499

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms

2023
Research progress on the protection and detoxification of phytochemicals against aflatoxin B
    Toxicon : official journal of the International Society on Toxinology, 2021, Volume: 195

    Topics: Aflatoxin B1; Chemical and Drug Induced Liver Injury; Hepatitis; Humans; Liver; Liver Neoplasms; Phytochemicals; Protective Agents

2021
Development of an adverse outcome pathway for chemically induced hepatocellular carcinoma: case study of AFB1, a human carcinogen with a mutagenic mode of action.
    Critical reviews in toxicology, 2018, Volume: 48, Issue:4

    Topics: Adverse Outcome Pathways; Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; DNA Adducts; Humans; Liver Neoplasms; Mutagens; Mutation

2018
Epigenetic alterations caused by aflatoxin b1: a public health risk in the induction of hepatocellular carcinoma.
    Translational research : the journal of laboratory and clinical medicine, 2019, Volume: 204

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Liver Neoplasms; MicroRNAs; Protein Biosynthesis; Public Health; Risk; RNA, Long Noncoding

2019
Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 124

    Topics: Aflatoxin B1; Animals; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Decontamination; DNA Adducts; Food Contamination; Gamma Rays; Growth Disorders; Humans; Immunologic Factors; Liver Neoplasms; Malnutrition; Occupational Exposure

2019
DNA damage checkpoint response to aflatoxin B1.
    Environmental toxicology and pharmacology, 2019, Volume: 65

    Topics: Aflatoxin B1; Animals; Ataxia Telangiectasia Mutated Proteins; Carcinogenesis; Carcinoma, Hepatocellular; DNA Damage; Humans; Liver Neoplasms; Oxidative Stress; Receptors, Death Domain

2019
Hepatocellular carcinoma in the noncirrhotic liver: a literature review.
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:7

    Topics: Aflatoxin B1; Age Distribution; Alcohol Drinking; beta Catenin; Carcinogenesis; Carcinoma, Hepatocellular; Cyclin-Dependent Kinase Inhibitor p21; DNA Methylation; Environmental Exposure; Food Contamination; Genes, Tumor Suppressor; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Oncogene Proteins; Prognosis

2019
A review of molecular mechanisms in the development of hepatocellular carcinoma by aflatoxin and hepatitis B and C viruses.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2013, Volume: 32, Issue:2

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; DNA Adducts; Hepacivirus; Hepatitis B virus; Humans; Lipid Peroxidation; Liver Neoplasms; Mutation; Tumor Suppressor Protein p53

2013
Quantitative assessment of the effect of glutathione S-transferase genes GSTM1 and GSTT1 on hepatocellular carcinoma risk.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:5

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Epistasis, Genetic; Genetic Predisposition to Disease; Genotype; Glutathione Transferase; Humans; Liver Neoplasms; Polymorphism, Genetic; Risk; Serum Albumin

2014
Pathogenesis of hepatocellular carcinoma according to aetiology.
    Best practice & research. Clinical gastroenterology, 2014, Volume: 28, Issue:5

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Hepatitis B; Hepatitis C; Humans; Liver Cirrhosis; Liver Neoplasms; Mutagenesis, Insertional; Point Mutation; Risk Factors; Tumor Suppressor Protein p53

2014
Dysregulation of apoptosis in hepatocellular carcinoma cells.
    World journal of gastroenterology, 2009, Feb-07, Volume: 15, Issue:5

    Topics: Aflatoxin B1; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Death; Cell Division; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Kinetics; Liver Neoplasms; Mice; Mice, Transgenic; Receptors, Death Domain; Transforming Growth Factor beta; Tumor Suppressor Protein p53

2009
[Relationship of single nucleotide polymorphism, environmental factors and the hereditary susceptibility of hepatocellular carcinoma].
    Wei sheng yan jiu = Journal of hygiene research, 2009, Volume: 38, Issue:2

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Liver Neoplasms; Polymorphism, Single Nucleotide

2009
[Mapping DNA damage to understand somatic mutagenesis].
    Medecine sciences : M/S, 2010, Volume: 26, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Codon; DNA; DNA Damage; DNA Methylation; DNA Repair; Genes, p53; Humans; Liver Neoplasms; Lung Neoplasms; Mutagenesis; Neoplasms, Radiation-Induced; Polymerase Chain Reaction; Skin Neoplasms; Sunlight; Ultraviolet Rays

2010
MicroRNA response to environmental mutagens in liver.
    Mutation research, 2011, Dec-01, Volume: 717, Issue:1-2

    Topics: Aflatoxin B1; Animals; Arsenic; Benzo(a)pyrene; Carcinoma, Hepatocellular; Environmental Pollutants; Ethanol; Gene Expression Regulation; Hepacivirus; Hepatitis B virus; Humans; Liver; Liver Neoplasms; MicroRNAs; Mutagens; Nicotiana; Poisons; Risk Factors; Rodenticides; Triazines

2011
Epidemiology of viral hepatitis and hepatocellular carcinoma.
    Gastroenterology, 2012, Volume: 142, Issue:6

    Topics: Aflatoxin B1; Biomarkers; Carcinoma, Hepatocellular; Coinfection; Cost of Illness; DNA, Viral; Epidemiologic Studies; Genotype; Global Health; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Incidence; Liver Cirrhosis; Liver Neoplasms; Meta-Analysis as Topic; Prevalence; Risk Assessment; Risk Factors; United States; Virus Replication

2012
TP53 codon 72 polymorphism with hepatocellular carcinoma: a metaanalysis.
    The Journal of international medical research, 2012, Volume: 40, Issue:2

    Topics: Aflatoxin B1; Alcohol Drinking; Asian People; Carcinoma, Hepatocellular; Case-Control Studies; Female; Gene Frequency; Genes, p53; Genetic Predisposition to Disease; Genotype; Hepatitis B; Hepatitis C; Humans; Liver Neoplasms; Male; Polymorphism, Single Nucleotide; Risk; Risk Factors; Tumor Suppressor Protein p53

2012
Dietary modulation of the biotransformation and genotoxicity of aflatoxin B(1).
    Toxicology, 2012, Sep-28, Volume: 299, Issue:2-3

    Topics: Aflatoxin B1; Animals; Brassica; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Humans; Inactivation, Metabolic; Liver Neoplasms; Mutagens

2012
The enemy at the gates? DNA adducts as biomarkers of exposure to exogenous and endogenous genotoxic agents.
    Toxicology letters, 2002, Aug-05, Volume: 134, Issue:1-3

    Topics: Aflatoxin B1; Animals; Biomarkers; Butadienes; DNA Adducts; Environmental Exposure; Environmental Monitoring; Humans; Liver Neoplasms; Mutagens

2002
Susceptibility and biomarker knowledge for improvement of environmental health.
    International journal of hygiene and environmental health, 2003, Volume: 206, Issue:4-5

    Topics: Aflatoxin B1; Aspergillus flavus; Biomarkers; Disease Susceptibility; Environmental Health; Global Health; Humans; International Cooperation; Liver Neoplasms; Mouth Neoplasms

2003
Synergistic interaction between aflatoxin B1 and hepatitis B virus in hepatocarcinogenesis.
    Liver international : official journal of the International Association for the Study of the Liver, 2003, Volume: 23, Issue:6

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; Food Contamination; Fungi; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms

2003
Hepatocellular carcinoma--a model of human cancer: clinico-pathological features, etiology and pathogenesis.
    Indian journal of pathology & microbiology, 2003, Volume: 46, Issue:1

    Topics: Aflatoxin B1; Alcohol Drinking; Carcinoma, Hepatocellular; Hepatitis B; Hepatitis C; Humans; Liver Neoplasms; Risk Factors

2003
The pathogenesis of hepatocellular carcinoma is multifactorial event. Novel immunological treatment in prospect.
    La Clinica terapeutica, 2004, Volume: 155, Issue:5

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Controlled Clinical Trials as Topic; Gene Expression; Genes, p53; Genetic Therapy; Hepatectomy; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Immunotherapy; Immunotherapy, Active; Interferon-alpha; Liver Cirrhosis; Liver Neoplasms; Liver Regeneration; Mice; Mice, Transgenic; Multicenter Studies as Topic; Mutation; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; T-Lymphocytes, Cytotoxic; Transforming Growth Factor beta

2004
[Molecular genetic and epigenetic mechanisms of hepatocarcinogenesis].
    Ai zheng = Aizheng = Chinese journal of cancer, 2005, Volume: 24, Issue:6

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Cyclin-Dependent Kinase Inhibitor p16; Gene Expression Regulation, Neoplastic; Genes, p53; Genetic Predisposition to Disease; Hepatitis B; Hepatitis C; Humans; Liver Cirrhosis, Alcoholic; Liver Neoplasms; Retinoblastoma Protein; Signal Transduction; Tumor Suppressor Protein p53; Wnt Proteins

2005
Somatic mutations in human cancer: applications in molecular epidemiology.
    Revue d'epidemiologie et de sante publique, 2005, Volume: 53, Issue:3

    Topics: Aflatoxin B1; Apoptosis; Breast Neoplasms; Carcinoma, Hepatocellular; Codon; Disease Progression; DNA Damage; DNA Fingerprinting; DNA Repair; DNA, Neoplasm; Female; Genes, p53; Hepatitis B; Humans; Liver Neoplasms; Male; Molecular Epidemiology; Mutagens; Mutation; Mutation, Missense; Neoplasms; Precancerous Conditions; Prognosis; Risk Factors; Time Factors; Tumor Suppressor Proteins

2005
The genetic and environmental basis of hepatocellular carcinoma.
    Discovery medicine, 2006, Volume: 6, Issue:35

    Topics: Aflatoxin B1; Alcoholism; Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genomic Instability; Hepatitis C; Humans; Liver Neoplasms; Models, Biological

2006
The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.
    Chemico-biological interactions, 2007, May-20, Volume: 168, Issue:1

    Topics: Aflatoxin B1; Biomarkers; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor; Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Female; Hepatocytes; Humans; Inhibitory Concentration 50; Liver Neoplasms; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Models, Biological; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Transcription Factors; Xenobiotics

2007
TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer.
    Oncogene, 2007, Apr-02, Volume: 26, Issue:15

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Hepatitis Viruses; Hepatitis, Chronic; Humans; Incidence; Liver Neoplasms; Mutagenesis; Mutation; Tumor Suppressor Protein p53

2007
A critical review of biological methods for the detection of fungal toxins in foods and foodstuffs.
    Journal of the science of food and agriculture, 1982, Volume: 33, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Artemia; Bacillus subtilis; Biological Assay; Carcinoma, Hepatocellular; Chick Embryo; Chromatography; False Positive Reactions; Fatty Acids; Food Contamination; Gas Chromatography-Mass Spectrometry; Humans; Liver Neoplasms; Mutagenicity Tests; Mycotoxins; T-2 Toxin; Time Factors; Trout

1982
Carcinogenesis and prevention strategy of liver cancer in areas of prevalence.
    Journal of cellular physiology. Supplement, 1984, Volume: 3

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxin M1; Aflatoxins; Aged; Animals; Carrier State; Child; Child, Preschool; China; Chromatography, High Pressure Liquid; DNA, Viral; Hepatitis B; Hepatitis B virus; Humans; Infant; Infant, Newborn; Liver Neoplasms; Middle Aged; Prospective Studies

1984
Cellular interactions and metabolism of aflatoxin: an update.
    Pharmacology & therapeutics, 1995, Volume: 65, Issue:2

    Topics: Abnormalities, Drug-Induced; Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; DNA; Humans; Liver Neoplasms; Mutation; Mycotoxicosis; Proteins; RNA; Structure-Activity Relationship

1995
p53 proteins and aflatoxin b1: the good, the bad, and the ugly.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:4 Pt 1

    Topics: Aflatoxin B1; Carcinogens; Carcinoma, Hepatocellular; Genes, p53; Humans; Liver Neoplasms; Mutation

1995
A review of the dose-response induction of DNA adducts by aflatoxin B1 and its implications to quantitative cancer-risk assessment.
    Mutation research, 1993, Volume: 296, Issue:3

    Topics: Aflatoxin B1; Animals; DNA; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Risk

1993
The genetics of human cancer: implications for ecotoxicology.
    Environmental health perspectives, 1994, Volume: 102 Suppl 12

    Topics: Aflatoxin B1; Animals; Carcinogens, Environmental; DNA Damage; Ecology; Environmental Exposure; Environmental Monitoring; Fishes; Genes, p53; Genes, ras; Genetic Markers; Humans; Liver Neoplasms; Mutagens; Neoplasms

1994
[Hepatocellular carcinoma: molecular biology aspects].
    Zentralblatt fur Chirurgie, 1994, Volume: 119, Issue:11

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Hepatitis B; Hepatitis C; Humans; Liver Cirrhosis, Alcoholic; Liver Neoplasms

1994
Mutagenesis of the H-ras protooncogene and the p53 tumor suppressor gene.
    Cancer research, 1994, Apr-01, Volume: 54, Issue:7 Suppl

    Topics: Aflatoxin B1; Base Sequence; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Codon; DNA Primers; Ethylnitrosourea; Genes, p53; Genes, ras; Humans; Liver Neoplasms; Molecular Sequence Data; Mutagenesis; Neoplasms; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proto-Oncogenes; Urinary Bladder Neoplasms

1994
Invited commentary--"molecular epidemiology": new pathway or new travelling companion?
    American journal of epidemiology, 1994, Jul-01, Volume: 140, Issue:1

    Topics: Aflatoxin B1; Biomarkers; Causality; Disease Susceptibility; Environmental Exposure; Epidemiologic Methods; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Molecular Epidemiology; Neoplasms; Prospective Studies; Research; Specialization; Terminology as Topic

1994
[Co-inactivation of the p53 and RB genes in human hepato cellular carcinoma].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:2

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Chromosome Aberrations; Gene Deletion; Genes, p53; Genes, Retinoblastoma; Heterozygote; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mutation; Polymorphism, Restriction Fragment Length; Risk Factors

1993
Molecular dosimetry of aflatoxin exposure: contribution to understanding the multifactorial etiopathogenesis of primary hepatocellular carcinoma with particular reference to hepatitis B virus.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; DNA; DNA Adducts; Epidemiologic Methods; Hepatitis B; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Serum Albumin

1993
Hepatocellular carcinoma--carcinogenesis updated.
    Singapore medical journal, 1995, Volume: 36, Issue:6

    Topics: Aflatoxin B1; Carcinogens, Environmental; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Hepatitis B; Humans; Liver; Liver Neoplasms; Risk Factors

1995
Molecular and genetic epidemiology of hepatocellular carcinoma: studies in China and Senegal.
    Princess Takamatsu symposia, 1995, Volume: 25

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; China; Hepatitis, Viral, Human; Humans; Liver Neoplasms; Male; Senegal

1995
Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis.
    Mutation research, 1996, Volume: 366, Issue:1

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Diet; DNA Adducts; DNA, Neoplasm; Genes, p53; Genes, ras; Humans; Liver Neoplasms; Oxidation-Reduction

1996
Carcinogen-DNA and protein adducts: biomarkers for cohort selection and modifiable endpoints in chemoprevention trials.
    Journal of cellular biochemistry. Supplement, 1996, Volume: 25

    Topics: Aflatoxin B1; Aflatoxins; Aged; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Clinical Trials as Topic; Cohort Studies; DNA Adducts; Guanine; Hepatitis B; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Proteins; Pyrazines; Risk Factors; Thiones; Thiophenes

1996
The molecular mechanism of aflatoxin B1-induced liver cancer: is mitotic recombination involved?
    Molecular carcinogenesis, 1997, Volume: 19, Issue:3

    Topics: Aflatoxin B1; Animals; Carcinogens; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mitosis; Recombination, Genetic

1997
Chemoprevention by inducers of carcinogen detoxication enzymes.
    Environmental health perspectives, 1997, Volume: 105 Suppl 4

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Enzyme Induction; Humans; Liver Neoplasms; Pyrazines; Rats; Thiones; Thiophenes

1997
[Aflatoxins: current concepts on mechanisms of toxicity and their involvement in the etiology of hepatocellular carcinoma].
    Revista de saude publica, 1997, Volume: 31, Issue:4

    Topics: Aflatoxin B1; Carcinogens; Carcinoma, Hepatocellular; Food Contamination; Humans; Incidence; Liver Neoplasms; Risk Factors

1997
Impacts of chemicals on liver cancer risk.
    Seminars in cancer biology, 2000, Volume: 10, Issue:3

    Topics: Aflatoxin B1; Animals; Carcinogens; DNA, Neoplasm; Genes, p53; Haplorhini; Hepatitis B; Hepatitis C; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Rats; Risk Factors

2000
The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis.
    Carcinogenesis, 2001, Volume: 22, Issue:4

    Topics: Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; Fishes; Genes, p53; Hepatitis B virus; Humans; Liver Neoplasms; Models, Biological; Models, Chemical; Mutagens; Mutation; Rats; Species Specificity

2001
Hepatitis B, aflatoxin B(1), and p53 codon 249 mutation in hepatocellular carcinomas from Guangxi, People's Republic of China, and a meta-analysis of existing studies.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:6

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; China; Diet; DNA Mutational Analysis; DNA, Neoplasm; Environmental Exposure; Genes, p53; Hepatitis B; Hepatitis B virus; Humans; Incidence; Liver Neoplasms; Point Mutation

2001
Role of phase 2 enzyme induction in chemoprotection by dithiolethiones.
    Mutation research, 2001, Sep-01, Volume: 480-481

    Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Carcinogens; Chemoprevention; China; Controlled Clinical Trials as Topic; Enzyme Induction; Gene Expression; Glucuronosyltransferase; Glutathione Transferase; Humans; Inactivation, Metabolic; Liver Neoplasms; Pyrazines; Quinone Reductases; Thiones; Thiophenes

2001
[Hepatocellular carcinoma without hepatitis virus markers].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 6

    Topics: Aflatoxin B1; Alcoholism; Carcinoma, Hepatocellular; DNA Virus Infections; Flaviviridae Infections; GB virus C; Glycogen Storage Disease; Hemochromatosis; Hepatitis, Viral, Human; Humans; Liver Neoplasms; Torque teno virus

2001
[Hepatocarcinogenesis with chemicals including mycotoxins].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 6

    Topics: Acetamides; Aflatoxin B1; Animals; Azo Compounds; Contraceptives, Oral; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mycotoxins

2001
Interindividual differences in response to chemoprotection against aflatoxin-induced hepatocarcinogenesis: implications for human biotransformation enzyme polymorphisms.
    Advances in experimental medicine and biology, 2001, Volume: 500

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Glutathione Transferase; Humans; Inactivation, Metabolic; Liver Neoplasms; Polymorphism, Genetic; Species Specificity

2001
[Dealing with genotoxic carcinogens].
    Voprosy pitaniia, 2002, Volume: 71, Issue:1

    Topics: Aflatoxin B1; Carcinogens; Food Contamination; Humans; Liver Neoplasms; Mutagens; Neoplasms

2002
Aflatoxins as risk factors for hepatocellular carcinoma in humans.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7 Suppl

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Codon; DNA, Neoplasm; Genes, ras; Hepatitis B; Humans; Liver Neoplasms; Risk Factors; Serum Albumin

1992
[Advances in the prevention of liver neoplasms in China].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1992, Volume: 26, Issue:2

    Topics: Aflatoxin B1; China; Hepatitis B; Humans; Liver Neoplasms; Mass Screening; Selenium; Tea

1992
Biological reactive intermediates of bisfuranoid mycotoxins.
    The Journal of toxicological sciences, 1990, Volume: 15 Suppl 4

    Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Anthraquinones; DNA; Humans; Liver Neoplasms; Mice; Mutagenesis; Mycotoxins; Rats; Serum Albumin; Sterigmatocystin

1990
Molecular dosimetry of hepatic aflatoxin B1-DNA adducts: linear correlation with hepatic cancer risk.
    Regulatory toxicology and pharmacology : RTP, 1989, Volume: 10, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; DNA; Humans; Liver Neoplasms; Risk Factors

1989
Hepatocellular carcinoma: possible etiologies in patients without serologic evidence of hepatitis B virus infection.
    Journal of medical virology, 1989, Volume: 27, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Alcoholism; alpha 1-Antitrypsin Deficiency; Carcinoma, Hepatocellular; Contraceptives, Oral; Hepatitis B; Hepatitis C; Humans; Liver Neoplasms; Schistosomiasis; Smoking

1989
Interactive effects of chemical carcinogens and hepatitis B virus in the pathogenesis of hepatocellular carcinoma.
    Cancer surveys, 1986, Volume: 5, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Carcinoma, Hepatocellular; Disease Models, Animal; Hepatitis B; Hepatitis B virus; Humans; Liver Neoplasms

1986

Trials

4 trial(s) available for aflatoxin b1 and Liver Neoplasms

ArticleYear
Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China.
    The American journal of clinical nutrition, 2006, Volume: 83, Issue:5

    Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; China; DNA Adducts; Double-Blind Method; Guanine; Humans; Lacticaseibacillus rhamnosus; Liver Neoplasms; Placebos; Probiotics; Propionibacterium; Risk Factors

2006
[Interaction among the relative risk factors of primary liver cancer in a case-control study].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 1994, Volume: 15, Issue:2

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Case-Control Studies; China; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Logistic Models; Risk Factors; Water Pollution

1994
Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by oltipraz in residents of Qidong, People's Republic of China.
    Journal of the National Cancer Institute, 1999, Feb-17, Volume: 91, Issue:4

    Topics: Acetylcysteine; Aflatoxin B1; Anticarcinogenic Agents; Carcinogens; China; Cytochrome P-450 CYP1A2; Double-Blind Method; Drug Administration Schedule; Feasibility Studies; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Liver Neoplasms; Pyrazines; Reproducibility of Results; Thiones; Thiophenes; Treatment Outcome

1999
Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Dec-04, Volume: 98, Issue:25

    Topics: Adult; Aflatoxin B1; Aflatoxins; Aged; Animals; Biomarkers; Carcinoma, Hepatocellular; China; Chlorophyllides; DNA Adducts; Female; Food Contamination; Guanine; Humans; Liver Neoplasms; Male; Middle Aged; Risk Factors

2001

Other Studies

306 other study(ies) available for aflatoxin b1 and Liver Neoplasms

ArticleYear
Environmental exposure and clinical correlates of hepatocellular carcinoma in New York City: a case only study.
    Cancer causes & control : CCC, 2022, Volume: 33, Issue:1

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Environmental Exposure; Humans; Liver Neoplasms; New York City

2022
Protective role of naringin loaded solid nanoparticles against aflatoxin B1 induced hepatocellular carcinoma.
    Chemico-biological interactions, 2022, Jan-05, Volume: 351

    Topics: Aflatoxin B1; Animals; Anti-Inflammatory Agents; Antioxidants; Carcinoma, Hepatocellular; Drug Carriers; Drug Liberation; Flavanones; Liver; Liver Neoplasms; Male; Nanoparticles; Rats, Wistar; Silymarin

2022
Exposure to aflatoxin B
    The Pan African medical journal, 2021, Volume: 40

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Follow-Up Studies; Hepacivirus; Hepatitis C; Humans; Liver Neoplasms; Pakistan; Risk Factors

2021
Protective effect of copper II-albumin complex against aflatoxin B1- induced hepatocellular toxicity: The impact of Nrf2, PPAR-γ, and NF-kB in these protective effects.
    Journal of food biochemistry, 2022, Volume: 46, Issue:11

    Topics: Aflatoxin B1; Albumins; Animals; Biomarkers; Carcinoma, Hepatocellular; Copper; Liver Neoplasms; NF-E2-Related Factor 2; NF-kappa B; PPAR gamma; Rats

2022
Aflatoxin levels and prevalence of TP53 aflatoxin-mutations in hepatocellular carcinomas in Mexico.
    Salud publica de Mexico, 2022, Feb-25, Volume: 64, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Mexico; Mutation; Prevalence; Tumor Suppressor Protein p53

2022
Aflatoxin B1 DNA-Adducts in Hepatocellular Carcinoma from a Low Exposure Area.
    Nutrients, 2022, Apr-15, Volume: 14, Issue:8

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cholangiocarcinoma; DNA Adducts; Liver Cirrhosis; Liver Neoplasms; Rats

2022
Aflatoxin M1 in milk does not contribute substantially to global liver cancer incidence.
    The American journal of clinical nutrition, 2022, 06-07, Volume: 115, Issue:6

    Topics: Aflatoxin B1; Aflatoxin M1; Animal Feed; Animals; Carcinoma, Hepatocellular; Food Contamination; Humans; Incidence; Liver Neoplasms; Milk

2022
Repurposing PDE5 inhibitor tadalafil and sildenafil as anticancer agent against hepatocellular carcinoma via targeting key events of glucose metabolism and multidrug resistance.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:8

    Topics: Aflatoxin B1; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Carbolines; Carcinoma, Hepatocellular; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Repositioning; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glucose; Imidazoles; Liver Neoplasms; Neoplasm Proteins; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rats; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride

2022
Evaluation of Toxicant-Associated Fatty Liver Disease and Liver Neoplastic Progress in Sprague-Dawley Rats Treated with Low Doses of Aflatoxin B1 Alone or in Combination with Extremely Low Frequency Electromagnetic Fields.
    Toxins, 2022, 05-03, Volume: 14, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Animals; Electromagnetic Fields; Fatty Liver; Female; Hyperplasia; Liver Neoplasms; Male; Rats; Rats, Sprague-Dawley

2022
Presence of aflatoxins in hazelnut paste in Turkey and a risk assessment study.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2022, Volume: 39, Issue:8

    Topics: Adult; Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Corylus; Food Contamination; Humans; Liver Neoplasms; Risk Assessment; Turkey

2022
Whole exome and transcript profiling of liver following aflatoxin B1 exposure in rats.
    Journal of applied toxicology : JAT, 2023, Volume: 43, Issue:9

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Exome; Liver; Liver Neoplasms; Rats; Rats, Inbred F344

2023
An
    Toxicology mechanisms and methods, 2023, Volume: 33, Issue:7

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Toxicogenetics

2023
Berberine-loaded albumin nanoparticles reverse aflatoxin B1-induced liver hyperplasia.
    BMC pharmacology & toxicology, 2023, 08-10, Volume: 24, Issue:1

    Topics: Aflatoxin B1; Albumins; Animals; Berberine; Carcinoma, Hepatocellular; Hyperplasia; Liver Neoplasms; Nanoparticles; Rats

2023
Low Frequency of Aflatoxin Induced TP53 Gene Codon 249 Mutation in Hepatocellular Carcinoma from Egyptian Patients Living in the Nile Delta Region.
    Asian Pacific journal of cancer prevention : APJCP, 2023, Sep-01, Volume: 24, Issue:9

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Hepatocellular; Codon; Egypt; Genes, p53; Humans; Liver Neoplasms; Mutation; Rabbits; Tumor Suppressor Protein p53

2023
Comprehensive analysis of aflatoxin B
    Journal of hazardous materials, 2024, 01-05, Volume: 461

    Topics: Aflatoxin B1; Aflatoxins; Aspergillus flavus; Cycloleucine; Epigenome; Humans; Liver Neoplasms; Transcriptome

2024
Analysis of miRNA-mRNA regulatory network revealed key genes induced by aflatoxin B1 exposure in primary human hepatocytes.
    Molecular genetics & genomic medicine, 2019, Volume: 7, Issue:11

    Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cells, Cultured; Computational Biology; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Hepatocytes; Humans; Liver Neoplasms; MicroRNAs; Poisons; Protein Interaction Maps; RNA, Messenger; Transcriptome

2019
HepG2-1A2 C2 and C7: Lentivirus vector-mediated stable and functional overexpression of cytochrome P450 1A2 in human hepatoblastoma cells.
    Toxicology letters, 2020, Feb-01, Volume: 319

    Topics: Aflatoxin B1; Cell Line, Tumor; Cytochrome P-450 CYP1A2; DNA Fingerprinting; Genetic Vectors; Hepatoblastoma; Humans; Lentivirus; Liver; Liver Neoplasms; Mycoplasma; Phenacetin; Plasmids

2020
Low-dose microcystin-LR antagonizes aflatoxin B1 induced hepatocarcinogenesis through decreasing cytochrome P450 1A2 expression and aflatoxin B1-DNA adduct generation.
    Chemosphere, 2020, Volume: 248

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A2; DNA Adducts; Hepatocytes; Humans; Liver; Liver Neoplasms; Male; Marine Toxins; Microcystins; Oxidative Stress; Rats

2020
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 09-01, Volume: 117, Issue:35

    Topics: Aflatoxin B1; Animals; Apoptosis; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cyclooxygenase 2; Cytokines; Disease Progression; Eicosanoids; Epoxide Hydrolases; Hep G2 Cells; Humans; Inflammation; Liver Neoplasms; Macrophages; Mice; Neoplastic Processes

2020
Unravelling the pathways of air plasma induced aflatoxin B
    Journal of hazardous materials, 2021, 02-05, Volume: 403

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Mass Spectrometry

2021
Comprehensive Metabolomic Analysis Reveals Dynamic Metabolic Reprogramming in Hep3B Cells with Aflatoxin B1 Exposure.
    Toxins, 2021, 05-27, Volume: 13, Issue:6

    Topics: Aflatoxin B1; Amino Acids; Apoptosis; Carcinoma, Hepatocellular; Humans; Lipid Metabolism; Liver Neoplasms; Metabolic Networks and Pathways; Metabolomics; Oxidative Stress; Purines; Pyrimidines; Tandem Mass Spectrometry; Tumor Cells, Cultured

2021
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma.
    Signal transduction and targeted therapy, 2021, 08-09, Volume: 6, Issue:1

    Topics: Active Transport, Cell Nucleus; Aflatoxin B1; Animals; B7-H1 Antigen; Carcinoma, Hepatocellular; Cell Line, Tumor; CRISPR-Cas Systems; Genome, Human; Hepatitis Viruses; Hepatocytes; Humans; Liver Neoplasms; Mice; Receptors, Aryl Hydrocarbon; Xenograft Model Antitumor Assays

2021
Prevalence of metabolic syndrome among adults with liver function injury in rural area of Southwest China: A cross-sectional study.
    Scientific reports, 2017, 07-17, Volume: 7, Issue:1

    Topics: Adult; Aflatoxin B1; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; China; Cross-Sectional Studies; DNA, Viral; Female; Hepatitis B; Humans; Liver; Liver Neoplasms; Logistic Models; Male; Metabolic Syndrome; Middle Aged; Prevalence; Risk Factors; Rural Population

2017
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors.
    Genome research, 2017, Volume: 27, Issue:9

    Topics: Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Line, Tumor; China; DNA Mutational Analysis; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Mice; Mutation

2017
Expression of P62 in hepatocellular carcinoma involving hepatitis B virus infection and aflatoxin B1 exposure.
    Cancer medicine, 2017, Volume: 6, Issue:10

    Topics: Adult; Aflatoxin B1; Biomarkers; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Follow-Up Studies; Gene Expression; Hepatitis B; Hepatitis B virus; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; NF-E2-Related Factor 2; Prognosis; RNA-Binding Proteins; RNA, Messenger; Signal Transduction; Survival Analysis; Tumor Burden

2017
Microcystin-LR increases genotoxicity induced by aflatoxin B1 through oxidative stress and DNA base excision repair genes in human hepatic cell lines.
    Environmental pollution (Barking, Essex : 1987), 2018, Volume: 233

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Catalase; Comet Assay; DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Glutathione; Guanine; Hepatocytes; Humans; Liver Neoplasms; Marine Toxins; Microcystins; Oxidative Stress; Superoxide Dismutase; Toxicity Tests

2018
Risks and Benefits of Increased Nut Consumption: Cardiovascular Health Benefits Outweigh the Burden of Carcinogenic Effects Attributed to Aflatoxin B₁ Exposure.
    Nutrients, 2017, Dec-13, Volume: 9, Issue:12

    Topics: Aflatoxin B1; Carcinogens; Cardiovascular Diseases; Cardiovascular System; Diet Surveys; Female; Food Contamination; Food Microbiology; Humans; Incidence; Liver Neoplasms; Male; Micronutrients; Middle Aged; Nuts; Risk Assessment; Sweden

2017
Aflatoxin and viral hepatitis exposures in Guatemala: Molecular biomarkers reveal a unique profile of risk factors in a region of high liver cancer incidence.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Adult; Aflatoxin B1; Aflatoxins; Aged; Aged, 80 and over; Albumins; Cross-Sectional Studies; Environmental Exposure; Female; Guatemala; Hepatitis B; Hepatitis C; Humans; Incidence; Liver Neoplasms; Male; Middle Aged; Risk Factors

2017
Fisetin Attenuates AKT Associated Growth Promoting Events in AflatoxinB1 Induced Hepatocellular Carcinoma.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:13

    Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; Drug Screening Assays, Antitumor; Flavonoids; Flavonols; Liver Neoplasms; Male; Proto-Oncogene Proteins c-akt; Rats; Structure-Activity Relationship

2018
Risk assessment of aflatoxin B1 exposure from maize and peanut consumption in Indonesia using the margin of exposure and liver cancer risk estimation approaches.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 113

    Topics: Aflatoxin B1; Arachis; Dietary Exposure; Humans; Indonesia; Liver Neoplasms; No-Observed-Adverse-Effect Level; Risk Assessment; Zea mays

2018
Droplet digital PCR detects high rate of TP53 R249S mutants in cell-free DNA of middle African patients with hepatocellular carcinoma.
    Clinical and experimental medicine, 2018, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Aflatoxin B1; Aged; Aged, 80 and over; alpha-Fetoproteins; Cameroon; Carcinoma, Hepatocellular; Case-Control Studies; Cell-Free Nucleic Acids; Central African Republic; DNA, Viral; Female; Gene Expression; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Middle Aged; Mutation Rate; Polymerase Chain Reaction; Tumor Suppressor Protein p53; Viral Load

2018
1α,25-Dihydroxyvitamin D
    The Journal of steroid biochemistry and molecular biology, 2018, Volume: 183

    Topics: Acyltransferases; Adaptor Proteins, Signal Transducing; Aflatoxin B1; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Dedifferentiation; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Hepatocytes; Humans; Liver Neoplasms; Mice; Mice, Inbred ICR; Phosphatidylinositol 3-Kinases; Phosphoproteins; Poisons; Proto-Oncogene Proteins c-akt; Stem Cells; Transcription Factors; Tumor Cells, Cultured; Vitamin D; Xenograft Model Antitumor Assays; YAP-Signaling Proteins

2018
Clinical features of aflatoxin B1-exposed patients with liver cancer and the molecular mechanism of aflatoxin B1 on liver cancer cells.
    Environmental toxicology and pharmacology, 2019, Volume: 71

    Topics: Aflatoxin B1; Aldo-Keto Reductases; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Cell Culture Techniques; Cell Proliferation; Environmental Pollutants; Female; Hep G2 Cells; Humans; Lipid Metabolism; Lipids; Liver; Liver Neoplasms; Male; Middle Aged

2019
Genetic polymorphisms in DNA repair genes XRCC4 and XRCC5 and aflatoxin B1-related hepatocellular carcinoma.
    Epidemiology (Cambridge, Mass.), 2013, Volume: 24, Issue:5

    Topics: Adult; Aflatoxin B1; Aged; Carcinoma, Hepatocellular; Case-Control Studies; Codon; DNA Helicases; DNA-Binding Proteins; Environmental Exposure; Female; Follow-Up Studies; Gene-Environment Interaction; Genetic Predisposition to Disease; Humans; Ku Autoantigen; Liver Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Risk Assessment; Time Factors

2013
Somatic changes in primary liver cancer in Russia: a pilot study.
    Mutation research, 2013, Aug-15, Volume: 755, Issue:2

    Topics: Adult; Aflatoxin B1; Aged; Aged, 80 and over; Axin Protein; beta Catenin; Carcinoma, Hepatocellular; Cholangiocarcinoma; Chromosomal Instability; Chromosomes, Human, Pair 18; Cohort Studies; Comorbidity; Female; Genes, p53; Genes, ras; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Liver Neoplasms; Loss of Heterozygosity; Male; Middle Aged; Monosomy; NF-E2-Related Factor 2; Pilot Projects; Point Mutation; Proto-Oncogene Proteins B-raf; PTEN Phosphohydrolase; Risk Factors; Russia; Young Adult

2013
Evaluation of hydro-alcoholic extract of Eclipta alba for its multidrug resistance reversal potential: an in vitro study.
    Nutrition and cancer, 2013, Volume: 65, Issue:5

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Proliferation; Chromatography, High Pressure Liquid; Doxorubicin; Drug Resistance, Neoplasm; Eclipta; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liquid-Liquid Extraction; Liver Neoplasms; Neoplasms; Plant Extracts; Transfection; Xenobiotics

2013
Protective effects of coffee against induction of DNA damage and pre-neoplastic foci by aflatoxin B₁.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:2

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Coffee; Comet Assay; DNA Damage; Glucuronosyltransferase; Glutathione; Glutathione S-Transferase pi; Liver; Liver Neoplasms; Male; Rats

2014
Transcriptome profiling of malignant transformed rat hepatic stem-like cells by aflatoxin B1.
    Neoplasma, 2014, Volume: 61, Issue:2

    Topics: Aflatoxin B1; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Neoplastic Stem Cells; Rats; Signal Transduction

2014
Genome-wide and differential proteomic analysis of hepatitis B virus and aflatoxin B1 related hepatocellular carcinoma in Guangxi, China.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Adult; Aflatoxin B1; Aged; Aldehyde Reductase; Aldo-Keto Reductases; Carcinoma, Hepatocellular; China; Chromosome Aberrations; Comparative Genomic Hybridization; Disease-Free Survival; Female; Gene Dosage; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Proteins; Proteomics; Risk; RNA, Messenger; RNA, Neoplasm; Young Adult

2013
Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct.
    Carcinogenesis, 2014, Volume: 35, Issue:7

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Chlorocebus aethiops; COS Cells; DNA Adducts; DNA Replication; DNA, Single-Stranded; Humans; Liver Neoplasms; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; Pyrimidines

2014
The p53 mutation spectrum in hepatocellular carcinoma from Guangxi, China : role of chronic hepatitis B virus infection and aflatoxin B1 exposure.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:3

    Topics: Adult; Aflatoxin B1; Carcinogenesis; Carcinoma, Hepatocellular; Case-Control Studies; Female; Genes, p53; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Prospective Studies; Tumor Suppressor Protein p53

2015
Genome-wide miRNA-profiling of aflatoxin B1-induced hepatic injury using deep sequencing.
    Toxicology letters, 2014, Apr-21, Volume: 226, Issue:2

    Topics: Aflatoxin B1; Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Computational Biology; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Markers; High-Throughput Nucleotide Sequencing; Liver; Liver Neoplasms; Male; MicroRNAs; Molecular Sequence Data; Rats; Rats, Inbred F344; Reproducibility of Results; RNA Precursors

2014
Aflatoxin B1 promotes cell growth and invasion in hepatocellular carcinoma HepG2 cells through H19 and E2F1.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:6

    Topics: Aflatoxin B1; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Chromatin Immunoprecipitation; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Poisons; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Long Noncoding; RNA, Messenger; RNA, Small Interfering

2014
Dietary intake of aflatoxins in the adult Malaysian population - an assessment of risk.
    Food additives & contaminants. Part B, Surveillance, 2012, Volume: 5, Issue:4

    Topics: Adult; Aflatoxin B1; Arachis; Diet; Environmental Exposure; Food Contamination; Fungi; Humans; Liver Neoplasms; Malaysia; Nuts; Risk Assessment; Risk Factors

2012
MicroRNA-24 modulates aflatoxin B1-related hepatocellular carcinoma prognosis and tumorigenesis.
    BioMed research international, 2014, Volume: 2014

    Topics: Adolescent; Adult; Aflatoxin B1; Aged; Carcinogenesis; Carcinoma, Hepatocellular; Gene Expression Regulation; Humans; Liver Neoplasms; MicroRNAs; Mycotoxins; Tumor Cells, Cultured; Young Adult

2014
Error-prone replication bypass of the primary aflatoxin B1 DNA adduct, AFB1-N7-Gua.
    The Journal of biological chemistry, 2014, Jun-27, Volume: 289, Issue:26

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Chlorocebus aethiops; COS Cells; DNA Adducts; DNA Damage; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Humans; Liver Neoplasms; Point Mutation

2014
Phenolic extract of Dialium guineense pulp enhances reactive oxygen species detoxification in aflatoxin B₁ hepatocarcinogenesis.
    Journal of medicinal food, 2014, Volume: 17, Issue:8

    Topics: Aflatoxin B1; Animals; Antioxidants; DNA Fragmentation; Fabaceae; Humans; Lipid Peroxidation; Liver; Liver Neoplasms; Male; Malondialdehyde; Oxidative Stress; Phenols; Plant Extracts; Rats; Rats, Wistar; Reactive Oxygen Species

2014
Association between aflatoxin B1 occupational airway exposure and risk of hepatocellular carcinoma: a case-control study.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:10

    Topics: Adult; Aflatoxin B1; Aflatoxins; Albumins; Carcinoma, Hepatocellular; Case-Control Studies; Dust; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inhalation Exposure; Liver Neoplasms; Male; Manufacturing Industry; Occupational Exposure; Paper; Risk Factors; Saccharum

2014
Lophirones B and C extenuate AFB1-mediated oxidative onslaught on cellular proteins, lipids, and DNA through Nrf-2 expression.
    Journal of biochemical and molecular toxicology, 2014, Volume: 28, Issue:12

    Topics: Aflatoxin B1; Animals; Antioxidants; Biflavonoids; DNA, Neoplasm; Lipid Metabolism; Liver Neoplasms; Male; Neoplasm Proteins; NF-E2-Related Factor 2; Oxidative Stress; Oxidoreductases; Poisons; Rats; Rats, Wistar

2014
Interaction of DNA repair gene polymorphisms and aflatoxin B1 in the risk of hepatocellular carcinoma.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:9

    Topics: Adult; Aflatoxin B1; Aged; Carcinoma, Hepatocellular; Case-Control Studies; Chi-Square Distribution; China; DNA Damage; DNA Repair; DNA Repair Enzymes; Female; Gene-Environment Interaction; Humans; Liver Neoplasms; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Polymorphism, Genetic; Risk Factors

2014
Public health risk associated with the co-occurrence of mycotoxins in spices consumed in Sri Lanka.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 74

    Topics: Aflatoxin B1; Capsicum; Carcinogens; Carcinoma, Hepatocellular; Diet; Food Contamination; Humans; Liver Neoplasms; Mycotoxins; Piper; Public Health; Risk Assessment; Spices; Sri Lanka

2014
Effect of 8-oxoguanine glycosylase deficiency on aflatoxin B1 tumourigenicity in mice.
    Mutagenesis, 2015, Volume: 30, Issue:3

    Topics: Adenoma; Aflatoxin B1; Animals; Carcinogenesis; Carcinogens; DNA Damage; DNA Glycosylases; Female; Liver Neoplasms; Lung Neoplasms; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout

2015
Inhibition effects of Chinese cabbage powder on aflatoxin B1-induced liver cancer.
    Food chemistry, 2015, Nov-01, Volume: 186

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Brassica; Diet; DNA Adducts; Female; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Temperature; Water

2015
Molecular characterization of hepatocarcinogenesis using mouse models.
    Disease models & mechanisms, 2015, Jul-01, Volume: 8, Issue:7

    Topics: Aflatoxin B1; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Profiling; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic

2015
Polymorphisms in the precursor microRNAs and aflatoxin B1-related hepatocellular carcinoma.
    Molecular carcinogenesis, 2016, Volume: 55, Issue:6

    Topics: ADAMTS4 Protein; Aflatoxin B1; Carcinoma, Hepatocellular; Case-Control Studies; Cell Line, Tumor; China; Female; Genetic Predisposition to Disease; Hep G2 Cells; Humans; Liver Neoplasms; Male; MicroRNAs; Mutation; Polymorphism, Single Nucleotide; Prognosis; Survival Analysis; Tumor Suppressor Protein p53

2016
Longitudinal evaluation of aflatoxin exposure in two cohorts in south-western Uganda.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2015, Volume: 32, Issue:8

    Topics: Adult; Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Cohort Studies; Environmental Exposure; Female; Food Contamination; Humans; Liver Neoplasms; Longitudinal Studies; Lysine; Male; Middle Aged; Rural Population; Serum Albumin; Uganda

2015
miR-34a screened by miRNA profiling negatively regulates Wnt/β-catenin signaling pathway in Aflatoxin B1 induced hepatotoxicity.
    Scientific reports, 2015, Nov-16, Volume: 5

    Topics: Aflatoxin B1; beta Catenin; Carcinoma, Hepatocellular; Cluster Analysis; Cyclin D1; DEAD-box RNA Helicases; Down-Regulation; Hep G2 Cells; Humans; Liver Neoplasms; MicroRNAs; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-myc; Real-Time Polymerase Chain Reaction; Ribonuclease III; RNA-Binding Proteins; RNA, Messenger; S Phase Cell Cycle Checkpoints; Sequence Analysis, RNA; Up-Regulation; Wnt Signaling Pathway

2015
MicroRNA Responses to the Genotoxic Carcinogens Aflatoxin B1 and Benzo[a]pyrene in Human HepaRG Cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 149, Issue:2

    Topics: Aflatoxin B1; Benzo(a)pyrene; Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Hepatocyte Nuclear Factor 4; Humans; Liver Neoplasms; MicroRNAs

2016
Polymorphisms of a Disintegrin and Metalloproteinase with Thrombospondin Motifs 5 and Aflatoxin B1-Related Hepatocellular Carcinoma.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016, Volume: 25, Issue:2

    Topics: ADAMTS5 Protein; Aflatoxin B1; Carcinoma, Hepatocellular; Case-Control Studies; Disintegrins; Female; Humans; Liver Neoplasms; Male; Metalloproteases; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Prognosis; Thrombospondins

2016
Crosstalk-eliminated quantitative determination of aflatoxin B1-induced hepatocellular cancer stem cells based on concurrent monitoring of CD133, CD44, and aldehyde dehydrogenase1.
    Toxicology letters, 2016, Jan-22, Volume: 243

    Topics: AC133 Antigen; Aflatoxin B1; Aldehyde Dehydrogenase; Antigens, CD; Carcinoma, Hepatocellular; DNA Adducts; Glycoproteins; Hep G2 Cells; Humans; Hyaluronan Receptors; Liver Neoplasms; Mutation; Neoplastic Stem Cells; Peptides

2016
Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma.
    Toxicology, 2016, 03-28, Volume: 350-352

    Topics: Aflatoxin B1; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; DNA Methylation; Epigenesis, Genetic; Epigenomics; Gene Expression Profiling; Hepatocytes; Humans; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Time Factors

2016
Studies on the biological functions of CPS1 in AFB1 induced hepatocarcinogenesis.
    Gene, 2016, Oct-10, Volume: 591, Issue:1

    Topics: Aflatoxin B1; Albumins; Carbamoyl-Phosphate Synthase (Ammonia); Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Immunoprecipitation; Keratin-1; Liver Neoplasms; Mass Spectrometry; Protein Binding

2016
[Docosahexaenoic acid inhibits aflatoxin B1-induced migration and invasion in hepatocellular carcinoma cells in vitro].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2016, Jun-20, Volume: 36, Issue:7

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Cell Cycle; Cell Movement; Docosahexaenoic Acids; Golgi Apparatus; Hep G2 Cells; Humans; Liver Neoplasms; Mitochondria; Neoplasm Invasiveness

2016
Distinct response of the hepatic transcriptome to Aflatoxin B1 induced hepatocellular carcinogenesis and resistance in rats.
    Scientific reports, 2016, 08-22, Volume: 6

    Topics: Aflatoxin B1; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Adhesion; Cell Proliferation; Drug Resistance; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; High-Throughput Nucleotide Sequencing; Liver; Liver Neoplasms; Male; Rats; RNA, Long Noncoding; Sequence Analysis, RNA

2016
Dietary exposure to aflatoxin B
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 98, Issue:Pt B

    Topics: Adult; Aflatoxin B1; Animals; Diet; Food Contamination; Fumonisins; Humans; Liver Neoplasms; Mycotoxins; Ochratoxins; Poisons; Risk Assessment; Vietnam

2016
AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249.
    Oncotarget, 2017, Mar-14, Volume: 8, Issue:11

    Topics: Aflatoxin B1; Aldehydes; Carcinoma, Hepatocellular; Codon; DNA Adducts; DNA Repair; Genes, p53; Hep G2 Cells; Humans; Lipid Peroxidation; Liver Neoplasms; Mutation

2017
Human aflatoxin albumin adducts quantitatively compared by ELISA, HPLC with fluorescence detection, and HPLC with isotope dilution mass spectrometry.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:7

    Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Humans; Incidence; Kenya; Liver Neoplasms; Lysine; Mass Spectrometry; Reproducibility of Results

2008
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.
    Cancer research, 2008, Aug-15, Volume: 68, Issue:16

    Topics: Administration, Oral; Aflatoxin B1; Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; DNA Adducts; Heme Oxygenase-1; Humans; Imidazoles; Leukemia; Liver Neoplasms; Macrophages; Male; Mice; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Phenanthrenes; Rats; Rats, Inbred F344; Reactive Oxygen Species

2008
Genomic profiling reveals an alternate mechanism for hepatic tumor promotion by perfluorooctanoic acid in rainbow trout.
    Environmental health perspectives, 2008, Volume: 116, Issue:8

    Topics: Aflatoxin B1; Animals; Caprylates; Carcinogenicity Tests; Clofibrate; Cluster Analysis; Dehydroepiandrosterone; Disease Models, Animal; Estradiol; Fluorocarbons; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomics; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Oncorhynchus mykiss; Peroxisomes; Signal Transduction

2008
Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 109, Issue:1

    Topics: Aflatoxin B1; Alcohols; Aldehyde Reductase; Aldehydes; Analysis of Variance; Animals; Animals, Genetically Modified; Carcinogens; DNA Adducts; Inactivation, Metabolic; Liver; Liver Neoplasms; Protein Glutamine gamma Glutamyltransferase 2; Proteins; Rats; Rats, Sprague-Dawley; Rats, Transgenic

2009
Aflatoxin B1 exposure, hepatitis B virus infection, and hepatocellular carcinoma in Taiwan.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:3

    Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Chi-Square Distribution; Female; Hepatitis B; Humans; Liver Neoplasms; Logistic Models; Male; Middle Aged; Risk Factors; Taiwan

2009
Protection against aflatoxin B1 in rat--a new look at the link between toxicity, carcinogenicity, and metabolism.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 109, Issue:1

    Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Animals, Genetically Modified; Aspergillus flavus; Carcinogens; Disease Models, Animal; DNA Adducts; Inactivation, Metabolic; Liver Neoplasms; Rats

2009
Natural occurrence of aflatoxins in Chinese peanut butter and sesame paste.
    Journal of agricultural and food chemistry, 2009, May-13, Volume: 57, Issue:9

    Topics: Aflatoxin B1; Aflatoxins; Arachis; Carcinogens; Carcinoma, Hepatocellular; China; European Union; Food Contamination; Liver Neoplasms; Seeds; Sesamum

2009
Establishment of cancer cell lines from rat hepatocholangiocarcinoma and assessment of the role of granulocyte-colony stimulating factor and hepatocyte growth factor in their growth, motility and survival.
    Journal of hepatology, 2009, Volume: 51, Issue:1

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cholangiocarcinoma; Granulocyte Colony-Stimulating Factor; Hepatectomy; Hepatocyte Growth Factor; Liver Neoplasms; Male; Neoplasm Metastasis; Proto-Oncogene Proteins c-met; Rats; Rats, Inbred F344; Receptors, Granulocyte Colony-Stimulating Factor

2009
In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; Cells, Cultured; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Genes, p53; Liver Neoplasms; Mice; Mice, Transgenic; Mutagenicity Tests; Mutation

2009
Differential mutagenicity of aflatoxin B1 in the liver of neonatal and adult mice.
    Environmental and molecular mutagenesis, 2010, Volume: 51, Issue:2

    Topics: Aflatoxin B1; Aging; Animals; DNA Damage; Dose-Response Relationship, Drug; Genes, Reporter; Genome; Humans; Liver; Liver Neoplasms; Male; Mice; Mutagenicity Tests; Point Mutation; Poisons; Transcription Factors; Viral Proteins

2010
The reduction of cell death and proliferation by p27(Kip1) minimizes DNA damage in an experimental model of genotoxicity.
    International journal of cancer, 2009, Nov-15, Volume: 125, Issue:10

    Topics: Aflatoxin B1; Animals; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Disease Models, Animal; DNA Damage; Hepatocytes; Humans; Immunoenzyme Techniques; Intracellular Signaling Peptides and Proteins; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2009
Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1.
    Toxicology and applied pharmacology, 2010, 02-01, Volume: 242, Issue:3

    Topics: Aflatoxin B1; Animals; Blotting, Southern; Blotting, Western; Carcinoma, Hepatocellular; Female; Glutathione Transferase; Humans; Liver Neoplasms; Male; Mice; Mice, Knockout; Models, Animal; Mutagenicity Tests; Mutagens; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Species Specificity

2010
XPD codon 312 and 751 polymorphisms, and AFB1 exposure, and hepatocellular carcinoma risk.
    BMC cancer, 2009, Nov-17, Volume: 9

    Topics: Adult; Aflatoxin B1; Aged; Asian People; Carcinoma, Hepatocellular; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Hepatitis B; Hepatitis C; Humans; Liver Neoplasms; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Factors; Sex Factors; Xeroderma Pigmentosum Group D Protein

2009
Red ginseng extract protects against aflatoxin B1 and fumonisins-induced hepatic pre-cancerous lesions in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:2

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Blood Chemical Analysis; Body Weight; Chemoprevention; Female; Fumonisins; Ginsenosides; Liver; Liver Neoplasms; Panax; Plant Extracts; Precancerous Conditions; Rats; Rats, Sprague-Dawley

2010
Evaluation of the genotoxic and anti-genotoxic activities of silybin in human hepatoma cells (HepG2).
    Mutagenesis, 2010, Volume: 25, Issue:3

    Topics: Aflatoxin B1; Benzo(a)pyrene; Bleomycin; Carcinoma, Hepatocellular; Cell Death; Cell Division; Cell Line, Tumor; DNA; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Endonucleases; Escherichia coli Proteins; Humans; Intracellular Space; Liver Neoplasms; Micronuclei, Chromosome-Defective; Mutagens; Reactive Oxygen Species; Silybin; Silymarin

2010
Epidemiology of chronic hepatitis B virus infection, hepatocellular carcinoma, and hepatitis B virus-induced hepatocellular carcinoma.
    Pathologie-biologie, 2010, Volume: 58, Issue:4

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Endemic Diseases; Female; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Risk; Sex Factors

2010
Effects of the TP53 p.R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: interaction with hepatitis B virus X protein.
    Carcinogenesis, 2010, Volume: 31, Issue:8

    Topics: Aflatoxin B1; Africa, Western; Asia, Southeastern; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; DNA Primers; Gene Silencing; Humans; Liver Neoplasms; Mutation; Polymorphism, Single Nucleotide; Risk Factors; RNA Interference; Trans-Activators; Tumor Suppressor Protein p53; Viral Regulatory and Accessory Proteins

2010
Proteomic analysis of the transitional endoplasmic reticulum in hepatocellular carcinoma: an organelle perspective on cancer.
    Biochimica et biophysica acta, 2010, Volume: 1804, Issue:9

    Topics: Aflatoxin B1; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Endoplasmic Reticulum; Humans; Liver Neoplasms; Male; Organelles; Poisons; Proteome; Rats; Rats, Inbred F344; Tandem Mass Spectrometry

2010
Genetic variations of hepatitis B virus and serum aflatoxin-lysine adduct on high risk of hepatocellular carcinoma in Southern Guangxi, China.
    Journal of hepatology, 2010, Volume: 53, Issue:4

    Topics: Adult; Aflatoxin B1; Carcinoma, Hepatocellular; Case-Control Studies; China; Environmental Exposure; Female; Genotype; Hepatitis B virus; Humans; Liver Neoplasms; Lysine; Male; Middle Aged; Risk Factors

2010
Polymorphism in xeroderma pigmentosum complementation group C codon 939 and aflatoxin B1-related hepatocellular carcinoma in the Guangxi population.
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:4

    Topics: Aflatoxin B1; Asian People; Carcinoma, Hepatocellular; Case-Control Studies; China; Codon; DNA-Binding Proteins; Humans; Liver Neoplasms; Polymorphism, Genetic

2010
Hepatocellular carcinoma and the underlying mechanisms.
    African health sciences, 2010, Volume: 10, Issue:1

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; DNA Repair; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Incidence; Liver Neoplasms; Mutation; Risk Factors; Trans-Activators; Tumor Suppressor Protein p53; Viral Regulatory and Accessory Proteins

2010
Aflatoxin and PAH exposure biomarkers in a U.S. population with a high incidence of hepatocellular carcinoma.
    The Science of the total environment, 2010, Nov-01, Volume: 408, Issue:23

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Aged; Biomarkers; Carcinoma, Hepatocellular; Creatinine; Diet; Environmental Exposure; Environmental Pollutants; Female; Hepatitis, Viral, Human; Humans; Liver Neoplasms; Lysine; Male; Middle Aged; Polycyclic Aromatic Hydrocarbons; Pyrenes; Texas; Young Adult

2010
Aetiological differences in demographical, clinical and pathological characteristics of hepatocellular carcinoma in The Gambia.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31, Issue:2

    Topics: Adult; Aflatoxin B1; Aged; Carcinoma, Hepatocellular; Demography; Female; Gambia; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis C; Hepatitis C Antigens; Humans; Liver Neoplasms; Male; Middle Aged; Mutation, Missense; Prevalence; Sex Factors; Tumor Suppressor Protein p53

2011
Co-contamination of aflatoxin B1 and fumonisin B1 in food and human dietary exposure in three areas of China.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2011, Volume: 28, Issue:4

    Topics: Adult; Aflatoxin B1; Aged; Carcinogens, Environmental; China; Diet; Esophageal Neoplasms; Female; Flour; Food Contamination; Fumonisins; Humans; Liver Neoplasms; Male; Middle Aged; Oryza; Plant Extracts; Risk Factors; Seeds; Surveys and Questionnaires; Zea mays

2011
Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31, Issue:4

    Topics: Aflatoxin B1; beta-Galactosidase; Blotting, Western; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Line, Tumor; Comet Assay; DNA Damage; Doxorubicin; Fluorescent Antibody Technique, Indirect; Humans; Immunoenzyme Techniques; Liver Neoplasms; Mutagenicity Tests; Mutation; Phosphorylation; Tumor Suppressor Protein p53

2011
Aflatoxin B1-DNA adduct formation and mutagenicity in livers of neonatal male and female B6C3F1 mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 122, Issue:1

    Topics: Aflatoxin B1; Age Factors; Animals; Animals, Newborn; Base Sequence; Carcinogenicity Tests; Carcinoma, Hepatocellular; DNA Adducts; Female; Guanine; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Mutagens; Mutation Rate; Sequence Analysis, DNA; Sex Factors

2011
Hepatic aflatoxin B1-DNA adducts and TP53 mutations in patients with hepatocellular carcinoma despite low exposure to aflatoxin B1 in southern Japan.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31, Issue:9

    Topics: Adolescent; Adult; Aflatoxin B1; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Chi-Square Distribution; DNA Adducts; DNA Mutational Analysis; Female; Hepatitis B Surface Antigens; Hepatitis C Antibodies; Humans; Immunohistochemistry; Japan; Liver Neoplasms; Male; Middle Aged; Mutation; Risk Assessment; Risk Factors; Tumor Suppressor Protein p53; Young Adult

2011
Role of aflatoxin B1 as a risk for primary liver cancer in north Indian population.
    Clinical biochemistry, 2011, Volume: 44, Issue:14-15

    Topics: Adult; Aflatoxin B1; Alcohol Drinking; Carcinoma, Hepatocellular; Case-Control Studies; Chronic Disease; Female; Food Analysis; Food Microbiology; Guanine; Hepatitis B; Hepatitis C; Humans; India; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Risk Factors

2011
Effect of probiotic fermented milk and chlorophyllin on gene expressions and genotoxicity during AFB₁-induced hepatocellular carcinoma.
    Gene, 2011, Dec-15, Volume: 490, Issue:1-2

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Chlorophyllides; Comet Assay; Cultured Milk Products; DNA Damage; Gene Expression; Liver Neoplasms; Male; Mutagens; Probiotics; Rats; Rats, Wistar

2011
RASSF1A hypermethylation is associated with aflatoxin B1 and polycyclic aromatic hydrocarbon exposure in hepatocellular carcinoma.
    Hepato-gastroenterology, 2012, Volume: 59, Issue:118

    Topics: Aflatoxin B1; Carcinogens, Environmental; Carcinoma, Hepatocellular; Chi-Square Distribution; China; DNA Adducts; DNA Methylation; Environmental Exposure; Female; Gene Expression Regulation, Neoplastic; Gene-Environment Interaction; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Polycyclic Aromatic Hydrocarbons; Prognosis; Risk Assessment; Risk Factors; RNA, Messenger; Time Factors; Tumor Suppressor Proteins

2012
TP53 R249S mutation, genetic variations in HBX and risk of hepatocellular carcinoma in The Gambia.
    Carcinogenesis, 2012, Volume: 33, Issue:6

    Topics: Adult; Aflatoxin B1; Carcinoma, Hepatocellular; Case-Control Studies; Female; Gambia; Genes, p53; Genetic Variation; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Trans-Activators; Tumor Suppressor Protein p53; Viral Regulatory and Accessory Proteins

2012
Aflatoxin B1 up-regulates insulin receptor substrate 2 and stimulates hepatoma cell migration.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Aflatoxin B1; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cell Movement; Hep G2 Cells; Humans; Insulin Receptor Substrate Proteins; Liver; Liver Neoplasms; Receptor, IGF Type 1; Signal Transduction

2012
Etiological and molecular profile of hepatocellular cancer from India.
    International journal of cancer, 2013, Jul-15, Volume: 133, Issue:2

    Topics: Adult; Aflatoxin B1; Aged; Carcinoma, Hepatocellular; DNA, Viral; Female; Fibrosis; Genotype; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; India; Liver Neoplasms; Male; Middle Aged; Odds Ratio; Phylogeny; Prognosis; Retrospective Studies; Risk Factors; RNA, Viral; Viral Load

2013
Dramatic reduction of liver cancer incidence in young adults: 28 year follow-up of etiological interventions in an endemic area of China.
    Carcinogenesis, 2013, Volume: 34, Issue:8

    Topics: Adult; Aflatoxin B1; Carcinoma, Hepatocellular; China; Endemic Diseases; Follow-Up Studies; Hepatitis B; Hepatitis B Vaccines; Humans; Incidence; Liver Neoplasms; Male; Middle Aged; Vaccination; Young Adult

2013
Polymorphisms in the coding region of X-ray repair complementing group 4 and aflatoxin B1-related hepatocellular carcinoma.
    Hepatology (Baltimore, Md.), 2013, Volume: 58, Issue:1

    Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; DNA Adducts; DNA-Binding Proteins; Humans; Liver Neoplasms; Neoplasm Metastasis; Prognosis

2013
High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma.
    Molecular carcinogenesis, 2002, Volume: 35, Issue:2

    Topics: Aflatoxin B1; Alternative Splicing; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 3; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; DNA Adducts; DNA Methylation; Female; Genes, Tumor Suppressor; HeLa Cells; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Proteins; Promoter Regions, Genetic; Protein Isoforms; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2002
Sensitivity of electrospray ionization mass spectrometry detection of codon 249 mutations in the p53 gene compared with RFLP.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:10 Pt 1

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Codon; DNA Mutational Analysis; Genes, p53; Humans; Liver Neoplasms; Mutation, Missense; Polymorphism, Restriction Fragment Length; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2002
Distribution of aflatoxins in product and by-products during glucose production from contaminated corn.
    Die Nahrung, 2002, Volume: 46, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Chromatography, High Pressure Liquid; Food Contamination; Food Handling; Food Microbiology; Glucose; Humans; Hydrochloric Acid; Hydrolysis; Liver Neoplasms; Starch; Zea mays

2002
Determinants of formation of aflatoxin-albumin adducts: a seven-township study in Taiwan.
    British journal of cancer, 2002, Oct-21, Volume: 87, Issue:9

    Topics: Adult; Aflatoxin B1; Aflatoxins; Albumins; Carcinoma, Hepatocellular; Case-Control Studies; Cross-Sectional Studies; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Female; Glutathione Transferase; Hepatitis B Surface Antigens; Hepatitis C Antibodies; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Taiwan

2002
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relationship to aflatoxin B1-DNA adducts and p53 mutation in hepatocellular carcinoma.
    International journal of cancer, 2003, Feb-10, Volume: 103, Issue:4

    Topics: Aflatoxin B1; Carcinogens; Carcinoma, Hepatocellular; CpG Islands; DNA; DNA Adducts; DNA Methylation; Gene Silencing; Genes, p53; Humans; Immunohistochemistry; Liver Neoplasms; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Odds Ratio; Promoter Regions, Genetic; Risk Factors; Tumor Cells, Cultured

2003
Hepatitis B and C viruses infection, lifestyle and genetic polymorphisms as risk factors for hepatocellular carcinoma in Haimen, China.
    Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:12

    Topics: Adult; Aflatoxin B1; Aged; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Carcinoma, Hepatocellular; Cytochrome P-450 CYP2E1; Female; Food Contamination; Hepatitis B; Hepatitis C; Humans; Life Style; Liver Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Smoking

2002
Protective effect of soybean saponins and major antioxidants against aflatoxin B1-induced mutagenicity and DNA-adduct formation.
    Journal of medicinal food, 2002,Winter, Volume: 5, Issue:4

    Topics: Aflatoxin B1; alpha-Tocopherol; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Carcinoma, Hepatocellular; DNA Adducts; Dose-Response Relationship, Drug; Glycine max; Humans; Liver Neoplasms; Mutagenicity Tests; Mutagens; Mutation; Saponins; Treatment Outcome; Tumor Cells, Cultured

2002
Susceptibility to aflatoxin B1-related primary hepatocellular carcinoma in mice and humans.
    Cancer research, 2003, Aug-01, Volume: 63, Issue:15

    Topics: Aflatoxin B1; Amino Acid Sequence; Animals; Carcinoma, Hepatocellular; Case-Control Studies; Cocarcinogenesis; Conserved Sequence; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mice, Transgenic; Middle Aged; Molecular Sequence Data

2003
Differential expression of genes during aflatoxin B(1)-induced hepatocarcinogenesis in tree shrews.
    World journal of gastroenterology, 2004, Feb-15, Volume: 10, Issue:4

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Tupaiidae

2004
Low hepatic glutathione S-transferase and increased hepatic DNA adduction contribute to increased tumorigenicity of aflatoxin B1 in newborn and partially hepatectomized mice.
    Toxicology letters, 2004, Mar-14, Volume: 148, Issue:1-2

    Topics: Aflatoxin B1; Animals; Animals, Newborn; Carcinoma, Hepatocellular; DNA Adducts; Glutathione Transferase; Hepatectomy; Hepatocytes; Liver Neoplasms; Mice

2004
Comparison of the expression of beta-catenin in hepatocellular carcinoma in areas with high and low levels of exposure to aflatoxin B1.
    Journal of surgical oncology, 2004, Jun-01, Volume: 86, Issue:3

    Topics: Adult; Aflatoxin B1; Aged; beta Catenin; Carcinoma, Hepatocellular; China; Cytoskeletal Proteins; Environmental Exposure; Female; Hepatitis B; Humans; Immunohistochemistry; Liver Neoplasms; Malaysia; Male; Middle Aged; Mutation; Sequence Analysis, DNA; Trans-Activators; Tumor Suppressor Protein p53

2004
Effect of diet on aflatoxin B1-DNA binding and aflatoxin B1-induced glutathione S-transferase placental form positive hepatic foci in the rat.
    Experimental & molecular medicine, 2004, Aug-31, Volume: 36, Issue:4

    Topics: Aflatoxin B1; Animals; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Diet; DNA; Glutathione Transferase; Hepatocytes; Liver Neoplasms; Microsomes, Liver; Rats

2004
Increased levels of aflatoxin-albumin adducts are associated with CYP3A5 polymorphisms in The Gambia, West Africa.
    Pharmacogenetics, 2004, Volume: 14, Issue:10

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Aged; Albumins; Base Sequence; Carcinoma, Hepatocellular; Child; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA; Female; Gambia; Gene Expression; Gene Frequency; Genetic Variation; Haplotypes; Humans; Liver Neoplasms; Male; Middle Aged; Mutagens; Polymorphism, Genetic; Risk Factors

2004
Susceptibility to aflatoxin B1-induced carcinogenesis correlates with tissue-specific differences in DNA repair activity in mouse and in rat.
    Cancer research, 2005, Feb-15, Volume: 65, Issue:4

    Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; DNA; DNA Repair; Female; Genetic Predisposition to Disease; Guanine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Mice; Pyrimidines; Rats; Rats, Sprague-Dawley; Species Specificity

2005
Silencing of glutathione S-transferase P1 by promoter hypermethylation and its relationship to environmental chemical carcinogens in hepatocellular carcinoma.
    Cancer letters, 2005, Apr-28, Volume: 221, Issue:2

    Topics: Aflatoxin B1; Carcinogens, Environmental; Carcinoma, Hepatocellular; DNA Adducts; DNA Methylation; DNA, Neoplasm; Environmental Exposure; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Liver Neoplasms; Male; Middle Aged; Polycyclic Aromatic Hydrocarbons; Promoter Regions, Genetic; Risk Factors; Taiwan

2005
Associated factors in modulating aflatoxin B1-albumin adduct level in three Chinese populations.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Age Distribution; Albumins; Analysis of Variance; Biomarkers; Carcinoma, Hepatocellular; Chi-Square Distribution; China; Cohort Studies; Endemic Diseases; Female; Hepatitis, Viral, Human; Humans; Incidence; Linear Models; Liver Neoplasms; Male; Probability; Registries; Severity of Illness Index; Sex Distribution

2005
Alleviation of aflatoxin B1-induced oxidative stress in HepG2 cells by volatile extract from Allii Fistulosi Bulbus.
    Life sciences, 2005, Oct-21, Volume: 77, Issue:23

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aflatoxin B1; Allium; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Deoxyguanosine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glutathione; Glutathione Transferase; Hepatocytes; Humans; Lipid Peroxidation; Liver Neoplasms; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Volatilization

2005
249ser p53 mutation in the serum of black southern African patients with hepatocellular carcinoma.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:8

    Topics: Adolescent; Adult; Aflatoxin B1; Age Factors; Aged; Biomarkers, Tumor; Diet; DNA, Neoplasm; Environmental Exposure; Female; Humans; Liver Neoplasms; Male; Middle Aged; Mutation; Population Groups; Prevalence; Serine; Sex Factors; South Africa; Tumor Suppressor Protein p53

2005
Use of a rainbow trout oligonucleotide microarray to determine transcriptional patterns in aflatoxin B1-induced hepatocellular carcinoma compared to adjacent liver.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 88, Issue:2

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Liver; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Oncorhynchus mykiss; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic

2005
[A study about the association of detoxication gene GSTM1 polymorphism and the susceptibility to aflatoxin B1-related hepatocellular carcinoma].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2005, Volume: 13, Issue:9

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Glutathione Transferase; Humans; Liver Neoplasms; Polymorphism, Genetic

2005
Skin tumorigenic potential of aflatoxin B1 in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:5

    Topics: Administration, Topical; Aflatoxin B1; Animals; Carcinogens; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Glutathione Transferase; Lipid Peroxidation; Liver; Liver Neoplasms; Mice; Poisons; Skin Neoplasms; Tetradecanoylphorbol Acetate

2006
Comparative acute and combinative toxicity of aflatoxin B1 and fumonisin B1 in animals and human cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:6

    Topics: Aflatoxin B1; Animals; Bronchi; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Survival; Cyprinodontiformes; Drug Interactions; Epithelial Cells; Food Contamination; Fumonisins; Humans; Liver Neoplasms; Male; Mycotoxins; Rats; Rats, Inbred F344

2006
[Study on the detoxication gene gstM1-gstT1-null and susceptibility to aflatoxin B1 related hepatocellular carcinoma in Guangxi].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2005, Volume: 26, Issue:10

    Topics: Adult; Aflatoxin B1; Aged; Alleles; Asian People; Carcinoma, Hepatocellular; Case-Control Studies; China; Environmental Exposure; Female; Genetic Predisposition to Disease; Genotype; Glutathione Transferase; Hepatitis B; Humans; Liver Neoplasms; Male; Middle Aged; Polymorphism, Genetic

2005
Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice.
    International journal of cancer, 2006, Aug-15, Volume: 119, Issue:4

    Topics: Aflatoxin B1; Animals; Base Sequence; Cell Transformation, Neoplastic; DNA, Complementary; Humans; Liver Neoplasms; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Survival Rate; Tumor Suppressor Protein p53

2006
Aflatoxin B1 and polycyclic aromatic hydrocarbon adducts, p53 mutations and p16 methylation in liver tissue and plasma of hepatocellular carcinoma patients.
    International journal of cancer, 2006, Sep-01, Volume: 119, Issue:5

    Topics: Adult; Aflatoxin B1; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cyclin-Dependent Kinase Inhibitor p16; DNA Adducts; DNA Methylation; Female; Genes, p16; Genes, p53; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Male; Middle Aged; Mutation; Polycyclic Aromatic Hydrocarbons; Tumor Suppressor Protein p53

2006
Protective effects of garlic sulfur compounds against DNA damage induced by direct- and indirect-acting genotoxic agents in HepG2 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:6

    Topics: Aflatoxin B1; Allyl Compounds; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cysteine; Disulfides; DNA Damage; Garlic; Humans; Liver Neoplasms; Mutagens; Sulfhydryl Compounds; Sulfides; Sulfinic Acids; Sulfur Compounds

2006
Clinical significance of aflatoxin, mutant P53 gene and sIL-2 receptor in liver cirrhosis and hepatocellular carcinoma.
    Journal of the Egyptian Society of Parasitology, 2006, Volume: 36, Issue:1

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; DNA Mutational Analysis; Female; Genes, p53; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Mutation; Receptors, Interleukin-2; Risk Factors

2006
Quantitative comparison of aflatoxin B1 serum albumin adducts in humans by isotope dilution mass spectrometry and ELISA.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:4

    Topics: Aflatoxin B1; Biomarkers; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Female; Guinea; Humans; Indicator Dilution Techniques; Isotopes; Liver Neoplasms; Male; Mass Spectrometry; Serum Albumin

2006
Molecular epidemiology of human liver cancer: insights into etiology, pathogenesis and prevention from The Gambia, West Africa.
    Carcinogenesis, 2006, Volume: 27, Issue:10

    Topics: Adult; Aflatoxin B1; Aged; Female; Gambia; Genes, p53; Hepatitis B; Hepatitis B Vaccines; Hepatitis C; Humans; Liver Neoplasms; Male; Middle Aged; Mutation; Public Health

2006
Hepatitis B virus x gene and cyanobacterial toxins promote aflatoxin B1-induced hepatotumorigenesis in mice.
    World journal of gastroenterology, 2006, May-21, Volume: 12, Issue:19

    Topics: Aflatoxin B1; Animals; Bacterial Toxins; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cyanobacteria Toxins; Dose-Response Relationship, Drug; Drug Synergism; Liver Neoplasms; Male; Marine Toxins; Mice; Mice, Transgenic; Microcystins; Peptides, Cyclic; Poisons; Polymerase Chain Reaction; Time Factors; Trans-Activators; Viral Regulatory and Accessory Proteins

2006
Potent protective effect of isoimperatorin against aflatoxin B1-inducible cytotoxicity in H4IIE cells: bifunctional effects on glutathione S-transferase and CYP1A.
    Carcinogenesis, 2006, Volume: 27, Issue:12

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Drugs, Chinese Herbal; Furocoumarins; Glutathione Transferase; Liver Neoplasms; Rats

2006
Novel adenine adducts, N7-guanine-AFB1 adducts, and p53 mutations in patients with schistosomiasis and aflatoxin exposure.
    Cancer detection and prevention, 2006, Volume: 30, Issue:6

    Topics: Adult; Aflatoxin B1; Animals; Carcinoma, Hepatocellular; DNA Adducts; Female; Genes, p53; Humans; Liver Neoplasms; Male; Mass Spectrometry; Middle Aged; Mutation; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis

2006
Urinary 8-oxodeoxyguanosine, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan.
    Carcinogenesis, 2007, Volume: 28, Issue:5

    Topics: Adult; Aflatoxin B1; Carcinoma, Hepatocellular; Case-Control Studies; Cohort Studies; Deoxyadenine Nucleotides; DNA Damage; Female; Hepatitis B; Humans; Liver Neoplasms; Male; Middle Aged; Oxidative Stress; Risk; Sex Factors; Taiwan

2007
Gene expression analysis during tumor enhancement by the dietary phytochemical, 3,3'-diindolylmethane, in rainbow trout.
    Carcinogenesis, 2007, Volume: 28, Issue:7

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Dietary Supplements; Estradiol; Gene Expression Profiling; Indoles; Liver; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Oncorhynchus mykiss; Plant Preparations

2007
Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.
    Carcinogenesis, 2007, Volume: 28, Issue:6

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Chlorophyll; Colonic Neoplasms; Liver Neoplasms; Male; Random Allocation; Rats; Rats, Inbred F344

2007
Evaluation of oxidative stress in a group of adolescents exposed to a high level of aflatoxin B1--a multi-center and multi-biomarker study.
    Carcinogenesis, 2007, Volume: 28, Issue:11

    Topics: Adolescent; Aflatoxin B1; Biomarkers; Child; Environmental Exposure; Female; Humans; Liver Neoplasms; Male; Oxidative Stress; Pilot Projects; Risk Assessment

2007
Hepatitis B virus infection contributes to oxidative stress in a population exposed to aflatoxin B1 and high-risk for hepatocellular carcinoma.
    Cancer letters, 2008, May-18, Volume: 263, Issue:2

    Topics: Adult; Aflatoxin B1; Biomarkers; Carcinoma, Hepatocellular; Female; Hepatitis B; Humans; Liver Neoplasms; Male; Middle Aged; Oxidative Stress; Risk

2008
Urinary 15-F2t-isoprostane, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan.
    Carcinogenesis, 2008, Volume: 29, Issue:5

    Topics: Aflatoxin B1; Biomarkers; Carcinoma, Hepatocellular; Death Certificates; Dinoprost; Hepatitis B; Humans; Interviews as Topic; Lipid Peroxidation; Liver Neoplasms; Mass Screening; Odds Ratio; Reference Values; Registries; Taiwan

2008
Proteome analysis of aflatoxin B1-induced hepatocarcinogenesis in tree shrew (Tupaia belangeri chinensis) and functional identification of candidate protein peroxiredoxin II.
    Proteomics, 2008, Volume: 8, Issue:7

    Topics: Adult; Aflatoxin B1; Aged; Animals; Carcinoma, Hepatocellular; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mass Spectrometry; Middle Aged; Peroxiredoxins; Reverse Transcriptase Polymerase Chain Reaction; Tupaia

2008
Modulatory effect of Gynandropsis gynandra L. on glucose metabolizing enzymes in aflatoxin B1-induced hepatocellular carcinoma in rats.
    Indian journal of biochemistry & biophysics, 2007, Volume: 44, Issue:6

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Glucose-6-Phosphate Isomerase; Glycolysis; Hexokinase; Liver Neoplasms; Male; Plant Extracts; Rats; Rats, Wistar

2007
Large-scale analysis of the genetic and epigenetic alterations in hepatocellular carcinoma from Southeast China.
    Mutation research, 2008, May-10, Volume: 641, Issue:1-2

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; China; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Hepatitis B; Hepatitis B virus; Hepatocytes; Humans; Liver; Liver Neoplasms; Male; Membrane Glycoproteins; Middle Aged; Mutation; Neoplasm Recurrence, Local; Survival Rate; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2008
The polymorphism of XRCC3 codon 241 and AFB1-related hepatocellular carcinoma in Guangxi population, China.
    Annals of epidemiology, 2008, Volume: 18, Issue:7

    Topics: Adult; Aflatoxin B1; Aged; Carcinoma, Hepatocellular; Case-Control Studies; China; Codon; DNA Damage; DNA Repair; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic

2008
[Pathogenesis of human cancer development due to environmental factors].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:12 Suppl

    Topics: Adult; Aflatoxin B1; Aflatoxins; Animals; Bronchi; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Metaproterenol; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Ochratoxins; p-Dimethylaminoazobenzene; Rats

1984
[Epidemiological analysis of the etiological relationship between primary hepatocarcinoma and hepatitis B virus].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 1984, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Age Factors; Aged; Carcinoma, Hepatocellular; Child; Child, Preschool; China; Female; Food Contamination; Hepatitis B; Hepatitis B Surface Antigens; Humans; Infant; Infant, Newborn; Liver Neoplasms; Male; Middle Aged; Sex Factors

1984
An enzyme-linked immunosorbent procedure for assaying aflatoxin B1.
    IARC scientific publications, 1984, Issue:59

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Enzyme-Linked Immunosorbent Assay; Gambia; Humans; Liver Neoplasms; Radioimmunoassay

1984
The particular traits of carcinogenesis induced in Wistar rats by aflatoxin B1. III. Porphyrins and the activity of gamma-glutamyltranspeptidase in primary hepatomas and in their tissue of origin.
    Neoplasma, 1981, Volume: 28, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Porphyrins; Rats; Rats, Inbred Strains; Sex Factors

1981
Effect of high and low dietary protein on the dosing and postdosing periods of aflatoxin B1-induced hepatic preneoplastic lesion development in the rat.
    Cancer research, 1983, Volume: 43, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Dietary Proteins; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Histocytochemistry; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Time Factors

1983
Dietary protein intervention during the postdosing phase of aflatoxin B1-induced hepatic preneoplastic lesion development.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Carcinogens; Dietary Proteins; Drug Administration Schedule; gamma-Glutamyltransferase; Histocytochemistry; Liver; Liver Neoplasms; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344

1983
The role of dietary aflatoxin in the genesis of hepatocellular cancer in developing countries.
    Lancet (London, England), 1984, Oct-27, Volume: 2, Issue:8409

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Child; Cocarcinogenesis; Developing Countries; Dietary Proteins; DNA Replication; Food Contamination; Hepatitis B; Humans; Kwashiorkor; Liver; Liver Neoplasms; Microsomes, Liver; Mixed Function Oxygenases

1984
Effect of ethanol consumed in combination with high or low fat diets on the postinitiation phase of hepatocarcinogenesis in the rat.
    The Journal of nutrition, 1984, Volume: 114, Issue:12

    Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Dietary Fats; Drug Synergism; Ethanol; gamma-Glutamyltransferase; Liver Diseases; Liver Neoplasms; Male; Rats; Rats, Inbred Strains; Vitamin A

1984
Further study of alpha benzene hexachloride inhibition of aflatoxin B1 hepatocarcinogenesis in rats.
    British journal of cancer, 1981, Volume: 43, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Hexachlorocyclohexane; Liver Neoplasms; Male; Rats; Rats, Inbred BUF; Time Factors

1981
Enhancement of Aflatoxin B1 induced liver carcinogenesis by portal diversion in the rat.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1981, Volume: 35, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Body Weight; Liver Neoplasms; Male; Organ Size; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Spleen

1981
Modification of beet and cabbage diets of aflatoxin B1-induced rat plasma alpha-foetoprotein elevation, hepatic tumorigenesis, and mutagenicity of urine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1982, Volume: 20, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Biotransformation; Diet; Dietary Fiber; Liver Neoplasms; Male; Mutagens; Rats; Rats, Inbred F344; Vegetables

1982
Changes in preneoplastic response to aflatoxin B1 in rats fed green beans, beets or squash.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1983, Volume: 21, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Diet; gamma-Glutamyltransferase; Liver Neoplasms; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred F344; Vegetables

1983
Ca2+/phospholipid-dependent protein kinase activity correlates to the ability of transformed liver cells to proliferate in Ca2+-deficient medium.
    Biochemical and biophysical research communications, 1983, Aug-30, Volume: 115, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Calcium Chloride; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Replication; Kinetics; Liver; Liver Neoplasms; Precancerous Conditions; Protein Kinase C; Protein Kinases; Rats

1983
Glucocorticoid enhancement of aflatoxin B1 cytotoxicity in differentiated rat hepatoma cultures.
    Annals of the New York Academy of Sciences, 1980, Volume: 349

    Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; Cell Line; Dexamethasone; Hybrid Cells; Liver Neoplasms; Methylcholanthrene; Rats

1980
Analysis of aflatoxin B1 in human tissues with high-pressure liquid chromatography.
    Toxicology and applied pharmacology, 1981, Volume: 58, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Humans; Liver; Liver Neoplasms; Mice; Reye Syndrome

1981
[Is aflatoxin B1 a hepatic carcinogen in man?].
    Gastroenterologie clinique et biologique, 1982, Volume: 6, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Rats

1982
Aflatoxins, B1, B2, G1, G2 in primary liver cell carcinoma.
    Toxicology letters, 1982, Volume: 10, Issue:2-3

    Topics: Adult; Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Female; Hepatitis B virus; Humans; Liver Neoplasms; Male

1982
Metabolic activation of benzo[a]pyrene, aflatoxin B1, and dimethylnitrosamine by a human hepatoma cell line.
    Mutation research, 1982, Volume: 94, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Dimethylnitrosamine; Humans; Liver Neoplasms; Middle Aged; Sister Chromatid Exchange

1982
Some aspects of the human carcinogenicity of aflatoxin B1 and 3, 4 benz [a] pyrene.
    International journal of epidemiology, 1982, Volume: 11, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Humans; Liver Neoplasms; Mice; Rats

1982
Sister-chromatid exchange induction by indirect mutagens/carcinogens, aryl hydrocarbon hydroxylase activity and benzo[alpha]pyrene metabolism in cultured human hepatoma cells.
    Mutation research, 1983, Volume: 109, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzopyrenes; Carcinoma, Hepatocellular; Cell Line; Crossing Over, Genetic; Cyclophosphamide; Enzyme Induction; Humans; Liver Neoplasms; Mutagenicity Tests; Sister Chromatid Exchange

1983
The effect of substituents in the aromatic ring on carcinogenicity of N-nitrosomethylaniline in F344 rats.
    Carcinogenesis, 1983, Volume: 4, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Aniline Compounds; Animals; Carcinogens; Esophageal Neoplasms; Leukemia, Experimental; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Pituitary Neoplasms; Rats; Rats, Inbred F344; Sister Chromatid Exchange; Stomach Neoplasms; Structure-Activity Relationship; Testicular Neoplasms

1983
The inhibitory effects of ethoxyquin on the carcinogenic action of aflatoxin B1 in rats.
    Cancer letters, 1983, Volume: 19, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ethoxyquin; Liver; Liver Neoplasms; Male; Microsomes, Liver; Organ Size; Quinolines; Rats; Rats, Inbred F344

1983
The requirement for glutathione S-transferase in the conjugation of activated aflatoxin B1 during aflatoxin hepatocarcinogenesis in the rat.
    Chemico-biological interactions, 1983, Jul-15, Volume: 45, Issue:2

    Topics: Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Chromatography, High Pressure Liquid; Glutathione Transferase; Liver Neoplasms; Male; Rats; Rats, Inbred F344

1983
Vitamin A and aflatoxin: effect on liver and colon cancer.
    Nutrition and cancer, 1983, Volume: 5, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzopyrene Hydroxylase; Cocarcinogenesis; Colonic Neoplasms; Glucuronidase; Glutathione; Liver Neoplasms; Male; Oxidoreductases, O-Demethylating; Rats; Rats, Inbred Strains; Vitamin A

1983
Relation between geographical distribution of liver cancer and climate-aflatoxin B1 in China.
    Scientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences, 1983, Volume: 26, Issue:11

    Topics: Aflatoxin B1; Aflatoxins; China; Climate; Factor Analysis, Statistical; Food Contamination; Humans; Humidity; Liver Neoplasms; Temperature

1983
The development of hepatocellular tumours following aflatoxin B1 exposure of the partially hepatectomised mouse.
    Carcinogenesis, 1984, Volume: 5, Issue:3

    Topics: Adenoma; Aflatoxin B1; Aflatoxins; Animals; Body Weight; Carcinogens; Hepatectomy; Liver Neoplasms; Liver Neoplasms, Experimental; Liver Regeneration; Male; Mice; Mice, Inbred Strains; Organ Size

1984
Establishment of fish hepatocyte cultures for use in in vitro carcinogenicity studies.
    National Cancer Institute monograph, 1984, Volume: 65

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Separation; Cell Survival; Cells, Cultured; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; DNA; DNA Repair; Fishes; Liver; Liver Neoplasms; Male; Methylnitronitrosoguanidine; Toxicology; Trout

1984
Effects of sequential exposure to aflatoxin B1 and diethylnitrosamine on vascular and stomach tissue and additional target organs in rats.
    Cancer research, 1980, Volume: 40, Issue:11

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Diethylnitrosamine; Hemangiosarcoma; Liver Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Stomach Neoplasms; Time Factors

1980
Characterization of aflatoxin BI (AFB) in human liver cancer.
    Research communications in chemical pathology and pharmacology, 1981, Volume: 31, Issue:1

    Topics: Adult; Aflatoxin B1; Aflatoxins; Aged; Female; Humans; Liver; Liver Neoplasms; Male; Microscopy, Fluorescence; Middle Aged

1981
Mechanism of the resistance to cytotoxicity which precedes aflatoxin B1 hepatocarcinogenesis.
    Carcinogenesis, 1981, Volume: 2, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Survival; Cricetinae; DNA-Directed RNA Polymerases; Drug Resistance; Glutathione; Glutathione Transferase; Liver Neoplasms; Mice; Neoplasms, Experimental; Orotic Acid; Rats

1981
Preferential attack of mitochondrial DNA by aflatoxin B1 during hepatocarcinogenesis.
    Science (New York, N.Y.), 1982, Jan-01, Volume: 215, Issue:4528

    Topics: Aflatoxin B1; Aflatoxins; Animals; DNA, Mitochondrial; Kinetics; Liver Neoplasms; Male; Mitochondria, Liver; Neoplasms, Experimental; Protein Biosynthesis; Rats; Transcription, Genetic

1982
Effects of dietary aroclor 1254 and cyclopropene fatty acids on hepatic enzymes in rainbow trout.
    Archives of environmental contamination and toxicology, 1982, Volume: 11, Issue:1

    Topics: 7-Alkoxycoumarin O-Dealkylase; Aflatoxin B1; Aflatoxins; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Diet; Fatty Acids, Unsaturated; Liver; Liver Neoplasms; Mixed Function Oxygenases; Oxygenases; Polychlorinated Biphenyls; Salmonidae; Trout

1982
Some practical problems arising from use of the gamma multihit model for risk estimation.
    Journal of toxicology and environmental health, 1981, Volume: 8, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Maximum Allowable Concentration; Models, Theoretical; Nitrilotriacetic Acid; Probability; Risk; Vinyl Chloride

1981
Chemicals, evolution, and cancer development: Rous-Whipple Award Lecture.
    The American journal of pathology, 1982, Volume: 108, Issue:3

    Topics: Adult; Aflatoxin B1; Aflatoxins; Animals; Biological Evolution; Carcinogens; Carcinogens, Environmental; Cell Differentiation; Cytoplasm; Diethylnitrosamine; Dimethylnitrosamine; Humans; Liver; Liver Neoplasms; Methylazoxymethanol Acetate; Mice; Models, Biological; Neoplasms; Neoplasms, Experimental; Precancerous Conditions; Rats; Time Factors

1982
Glutathione and aflatoxin-B1-induced liver tumors: requirement for an intact glutathione molecule for regression of malignancy in neoplastic tissue.
    Annals of the New York Academy of Sciences, 1982, Dec-10, Volume: 397

    Topics: Aflatoxin B1; Aflatoxins; Animals; Autoradiography; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Female; Glutathione; Intestinal Absorption; Liver; Liver Neoplasms; Rats; Rats, Inbred Strains; Tissue Distribution

1982
[Antigenic relationships between hepatitis type B and primary carcinoma of the liver].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 1982, Volume: 3, Issue:1

    Topics: Adult; Aflatoxin B1; Aflatoxins; Female; Food Contamination; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Middle Aged

1982
Quantitative carcinogenesis and dosimetry in rainbow trout for aflatoxin B1 and aflatoxicol, two aflatoxins that form the same DNA adduct.
    Mutation research, 1994, Volume: 313, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogenicity Tests; Carcinogens; DNA; DNA Adducts; Liver Neoplasms; Models, Biological; Oncorhynchus mykiss; Ovum

1994
Codon 249 mutation of the p53 gene is a rare event in hepatocellular carcinomas from ethnic Chinese in Singapore.
    British journal of cancer, 1995, Volume: 72, Issue:1

    Topics: Adult; Aflatoxin B1; Aged; Base Sequence; Carcinoma, Hepatocellular; China; Codon; Female; Genes, p53; Humans; Liver Neoplasms; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Singapore

1995
Characterization of a murine p53ser246 mutant equivalent to the human p53ser249 associated with hepatocellular carcinoma and aflatoxin exposure.
    Molecular carcinogenesis, 1995, Volume: 13, Issue:2

    Topics: Aflatoxin B1; Amino Acid Sequence; Animals; Arginine; Base Sequence; Carcinoma, Hepatocellular; Codon; Creatine Kinase; Genes, p53; Hepatitis B; Humans; Liver Neoplasms; Mice; Molecular Sequence Data; Mutation; Neoplastic Stem Cells; Osteosarcoma; Promoter Regions, Genetic; Protein Conformation; Sequence Homology, Amino Acid; Serine; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1995
Aflatoxin exposure in Singapore: blood aflatoxin levels in normal subjects, hepatitis B virus carriers and primary hepatocellular carcinoma patients.
    Medicine, science, and the law, 1994, Volume: 34, Issue:4

    Topics: Adult; Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Environmental Exposure; Female; Food Contamination; Hepatitis B; Humans; Liver Neoplasms; Male; Middle Aged; Singapore

1994
p53 mutations in nonmalignant human liver: fingerprints of aflatoxins?
    Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:2

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Genes, p53; Humans; Liver Neoplasms; Mutation

1995
[Risk analysis of combination effects of risk factors for primary liver cancer].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1994, Volume: 28, Issue:6

    Topics: Aflatoxin B1; Case-Control Studies; China; Hepatitis B; Humans; Liver Neoplasms; Models, Statistical; Risk Factors; Water Pollution

1994
Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Mar-14, Volume: 92, Issue:6

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Case-Control Studies; China; Codon; DNA; Epoxide Hydrolases; Genes, p53; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutathione Transferase; Hepatitis B Surface Antigens; Humans; Inactivation, Metabolic; Liver Neoplasms; Point Mutation; Polymerase Chain Reaction; Reference Values; Risk Factors; Serum Albumin

1995
Metabolism and cytotoxicity of aflatoxin B1 in cultured rat hepatocytes and nonparenchymal cells: implications for tumorigenesis.
    Toxicology and applied pharmacology, 1994, Volume: 129, Issue:1

    Topics: Aflatoxin B1; Animals; Binding Sites; Carcinogenicity Tests; Carcinoma, Hepatocellular; Cell Count; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Dose-Response Relationship, Drug; Drug Storage; Glutathione Transferase; Kupffer Cells; L-Lactate Dehydrogenase; Liver; Liver Neoplasms; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Solubility; Water

1994
Biochemical and histochemical properties of hepatic tumors of rainbow trout, Oncorhynchus mykiss.
    Carcinogenesis, 1993, Volume: 14, Issue:2

    Topics: Aflatoxin B1; Aldehyde Dehydrogenase; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Disease Models, Animal; gamma-Glutamyltransferase; Glucuronosyltransferase; Glutathione Transferase; Immunohistochemistry; Liver; Liver Neoplasms; NAD(P)H Dehydrogenase (Quinone); Oxidoreductases; Trout; Uridine Diphosphate Glucose Dehydrogenase

1993
The effects of D-fenfluramine on the development of aflatoxin-B1 induced GGT+ hepatic foci in F344 rats.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1993, Volume: 17, Issue:4

    Topics: Adipose Tissue; Aflatoxin B1; Animals; Blood Chemical Analysis; Body Weight; Carrier Proteins; Diet; Eating; Fenfluramine; gamma-Glutamyltransferase; Ion Channels; Liver Neoplasms; Male; Membrane Proteins; Mitochondrial Proteins; Organ Size; Rats; Rats, Inbred F344; Uncoupling Protein 1

1993
[Study on the relationship between dietary aflatoxin B1 levels in foods and aflatoxin M1 excretion levels in children's urine in Guangxi].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1993, Volume: 27, Issue:4

    Topics: Adolescent; Aflatoxin B1; Aflatoxin M1; Child; Child, Preschool; Edible Grain; Female; Food Microbiology; Fungi; Humans; Infant; Liver Neoplasms; Male

1993
Preventive action of garlic on aflatoxin B1-induced carcinogenesis in the toad Bufo regularis.
    Nutrition and cancer, 1994, Volume: 21, Issue:1

    Topics: Aflatoxin B1; Animals; Bufonidae; Female; Garlic; Kidney Neoplasms; Liver Neoplasms; Male; Plant Extracts; Plant Oils; Plants, Medicinal

1994
Geographic variation of p53 mutational profile in nonmalignant human liver.
    Science (New York, N.Y.), 1994, May-27, Volume: 264, Issue:5163

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; China; Codon; Genes, p53; Humans; Liver; Liver Neoplasms; Point Mutation; Thailand; United States

1994
In vitro metabolism of aflatoxin B1 by normal and tumorous liver tissue from Thailand.
    Carcinogenesis, 1993, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Aflatoxin B1; Aged; Cytochrome P-450 Enzyme System; Female; Glutathione Transferase; Humans; Isoenzymes; Liver Neoplasms; Male; Microsomes, Liver; Middle Aged; Thailand

1993
Duck hepatitis B virus infection, aflatoxin B1 and liver cancer in domestic Chinese ducks.
    British journal of cancer, 1994, Volume: 69, Issue:1

    Topics: Aflatoxin B1; Animals; Base Sequence; Carcinoma, Hepatocellular; China; DNA Damage; DNA, Neoplasm; DNA, Viral; Ducks; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Liver; Liver Neoplasms; Molecular Sequence Data; Polymerase Chain Reaction; Poultry Diseases; Risk Factors

1994
Molecular epidemiology of aflatoxin exposures: validation of aflatoxin-N7-guanine levels in urine as a biomarker in experimental rat models and humans.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Animals; Biomarkers; China; DNA; DNA Adducts; DNA Damage; Female; Gambia; Guanine; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Rats; Rats, Inbred F344

1993
Exposure to aflatoxin B1 in animal-feed production plant workers.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Adult; Aflatoxin B1; Animal Feed; Enzyme-Linked Immunosorbent Assay; Food Handling; Humans; Liver Neoplasms; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Protein Binding; Sensitivity and Specificity; Serum Albumin

1993
p53 mutations and aflatoxin B1 exposure in hepatocellular carcinoma patients from Thailand.
    International journal of cancer, 1993, Jan-02, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Aflatoxin B1; Aged; Amino Acid Sequence; Carcinoma, Hepatocellular; DNA, Neoplasm; Female; Genes, p53; Genotype; Glutathione Transferase; Humans; Liver Neoplasms; Male; Middle Aged; Molecular Sequence Data; Mutation; Prevalence

1993
Aberrations of p53 gene in human hepatocellular carcinoma from China.
    Carcinogenesis, 1993, Volume: 14, Issue:2

    Topics: Aflatoxin B1; Base Sequence; Blotting, Southern; Carcinoma, Hepatocellular; China; Chromosome Aberrations; DNA, Neoplasm; DNA, Single-Stranded; Environmental Exposure; Genes, p53; Hepatitis B; Humans; Liver Neoplasms; Methylation; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Risk Factors

1993
Detection of aflatoxin B1-DNA adducts in human placenta and cord blood.
    Cancer research, 1993, Mar-15, Volume: 53, Issue:6

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; DNA; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Humans; Liver Neoplasms; Placenta; Pregnancy

1993
Immunohistochemical detection of aflatoxin B1-DNA adducts and hepatitis B virus antigens in hepatocellular carcinoma and nontumorous liver tissue.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; DNA; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hepatitis B Antigens; Hepatitis B Surface Antigens; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Rats; Trans-Activators; Viral Regulatory and Accessory Proteins

1993
Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Sep-15, Volume: 90, Issue:18

    Topics: Aflatoxin B1; Animals; Base Composition; Base Sequence; Biotransformation; Carcinoma, Hepatocellular; Codon; DNA Mutational Analysis; Genes, p53; Humans; Liver; Liver Neoplasms; Microsomes, Liver; Molecular Sequence Data; Mutagens; Point Mutation; Rats; Tumor Cells, Cultured

1993
Identification of a new P450 subfamily, CYP4F1, expressed in rat hepatic tumors.
    Archives of biochemistry and biophysics, 1993, Volume: 300, Issue:1

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Amino Acid Sequence; Animals; Antisense Elements (Genetics); Base Sequence; Blotting, Northern; Blotting, Western; Clofibrate; Cytochrome P-450 Enzyme System; Humans; Liver Neoplasms; Male; Microsomes; Molecular Sequence Data; Multigene Family; Rats; Sequence Homology, Amino Acid

1993
Activation of the c-Ki-ras oncogene in aflatoxin B1-induced hepatocellular carcinoma and adenoma in the rat: detection by denaturing gradient gel electrophoresis.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Mar-01, Volume: 90, Issue:5

    Topics: Adenoma; Aflatoxin B1; Animals; Base Sequence; Electrophoresis, Agar Gel; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); Rats

1993
Changes in GTP-dependent fusion and ras-related proteins in membranes from rat hepatocellular carcinomas.
    Cancer letters, 1995, Nov-27, Volume: 98, Issue:1

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum, Rough; Golgi Apparatus; Guanosine Triphosphate; Intracellular Membranes; Liver Neoplasms; Male; Membrane Fusion; Microsomes, Liver; Protein Binding; ras Proteins; Rats; Rats, Inbred F344; Subcellular Fractions

1995
Effect of eugenol on the genotoxicity of established mutagens in the liver.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1996, Volume: 34, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Antimutagenic Agents; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; DNA; Electrophoresis, Agar Gel; Eugenol; Glutathione Transferase; Humans; Liver; Liver Neoplasms; Male; Micronucleus Tests; Mutagenicity Tests; Mutagens; Rats; Rats, Wistar; Salmonella typhimurium; Tumor Cells, Cultured

1996
An aflatoxin-associated mutational hotspot at codon 249 in the p53 tumor suppressor gene occurs in hepatocellular carcinomas from Mexico.
    Carcinogenesis, 1996, Volume: 17, Issue:5

    Topics: Adult; Aflatoxin B1; Aged; Animals; Base Sequence; Carcinogens; Carcinoma, Hepatocellular; Codon; Female; Genes, p53; Hepatitis B; Hepatitis C; Humans; Liver Neoplasms; Male; Middle Aged; Molecular Sequence Data; Mutation; Rabbits; Serum Albumin

1996
Mutational properties of the primary aflatoxin B1-DNA adduct.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Feb-20, Volume: 93, Issue:4

    Topics: Aflatoxin B1; Bacteriophage M13; Base Sequence; Carcinoma, Hepatocellular; DNA Adducts; DNA, Viral; Escherichia coli; Guanine; Humans; Liver Neoplasms; Models, Molecular; Molecular Sequence Data; Mutagenesis; SOS Response, Genetics; Structure-Activity Relationship

1996
Chronic hepatitis B carriers with null genotypes of glutathione S-transferase M1 and T1 polymorphisms who are exposed to aflatoxin are at increased risk of hepatocellular carcinoma.
    American journal of human genetics, 1996, Volume: 59, Issue:1

    Topics: Adult; Aflatoxin B1; Aflatoxins; Aged; Albumins; Carcinoma, Hepatocellular; Carrier State; Cohort Studies; Genotype; Glutathione Transferase; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Taiwan

1996
Involvement of cytochrome P450, glutathione S-transferase, and epoxide hydrolase in the metabolism of aflatoxin B1 and relevance to risk of human liver cancer.
    Environmental health perspectives, 1996, Volume: 104 Suppl 3

    Topics: Aflatoxin B1; Animals; Carcinogens; Cytochrome P-450 Enzyme System; DNA Adducts; Epoxide Hydrolases; Escherichia coli; Glutathione Transferase; Humans; Hydrolysis; Liver Neoplasms; Oxidation-Reduction; Rats; Recombinant Proteins

1996
Effects of multiple risk factors for hepatocellular carcinoma on formation of aflatoxin B1-DNA adducts.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1996, Volume: 5, Issue:8

    Topics: Aflatoxin B1; Age Factors; Alcohol Drinking; Biomarkers; Carcinogens; Carcinoma, Hepatocellular; Carrier State; DNA Adducts; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Logistic Models; Male; Multivariate Analysis; Prospective Studies; Risk Factors; Smoking; Taiwan

1996
Inhibition of aflatoxin B1- and N-nitrosodiethylamine-induced liver preneoplastic foci in rats fed naturally occurring allyl sulfides.
    Nutrition and cancer, 1996, Volume: 25, Issue:1

    Topics: Aflatoxin B1; Allyl Compounds; Animals; Anticarcinogenic Agents; Diet; Diethylnitrosamine; Disulfides; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Wistar; Sulfides

1996
Allele-specific PCR analysis of p53 codon 249 AGT transversion in liver tissues from patients with viral hepatitis.
    International journal of cancer, 1996, Sep-27, Volume: 68, Issue:1

    Topics: Adult; Aflatoxin B1; Aged; Alleles; Base Sequence; Codon; Female; Genes, p53; Hepatitis B; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Molecular Sequence Data; Mozambique; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length

1996
Epidemiology of human aflatoxin exposures and their relationship to liver cancer.
    Progress in clinical and biological research, 1996, Volume: 395

    Topics: Adult; Aflatoxin B1; Arachis; Biomarkers; Carcinogens, Environmental; Carcinoma, Hepatocellular; Case-Control Studies; Diet; DNA Damage; Edible Grain; Environmental Exposure; Food Contamination; Food Microbiology; Genes, p53; Humans; Liver Neoplasms

1996
Lack of tumor-promoting effects of flavonoids: studies on rat liver preneoplastic foci and on in vivo and in vitro gap junctional intercellular communication.
    Nutrition and cancer, 1996, Volume: 26, Issue:3

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinogens; Cell Line; Cricetinae; Flavanones; Flavones; Flavonoids; Gap Junctions; Glutathione Transferase; Hepatectomy; Liver Neoplasms; Male; Phenobarbital; Precancerous Conditions; Quercetin; Rats; Rats, Wistar

1996
Absence of mutations in the p53 tumor suppressor gene in woodchuck hepatocellular carcinomas associated with hepadnavirus infection and intake of aflatoxin B1.
    Carcinogenesis, 1996, Volume: 17, Issue:12

    Topics: Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; DNA, Viral; Exons; Genes, p53; Hepatitis B; Hepatitis B Virus, Woodchuck; Liver Neoplasms; Marmota; Mutation

1996
Potentiation of aflatoxin B1-induced hepatocarcinogenesis in the rat by pretreatment with buthionine sulfoximine.
    Cancer letters, 1997, Feb-26, Volume: 113, Issue:1-2

    Topics: Aflatoxin B1; Animals; Buthionine Sulfoximine; Carcinogens; Drug Synergism; Enzyme Inhibitors; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms; Male; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred F344; Time Factors

1997
Effects of carotenoid-rich food extracts on the development of preneoplastic lesions in rat liver and on in vivo and in vitro antioxidant status.
    Nutrition and cancer, 1997, Volume: 27, Issue:3

    Topics: Aflatoxin B1; Animals; Carcinogens; Carotenoids; Catalase; Daucus carota; Food; Fruit; gamma-Glutamyltransferase; Glutathione; Hemolysis; Liver; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Solanum lycopersicum; Superoxide Dismutase

1997
Plasma antioxidant vitamins, chronic hepatitis B virus infection and urinary aflatoxin B1-DNA adducts in healthy males.
    Carcinogenesis, 1997, Volume: 18, Issue:6

    Topics: Adult; Aflatoxin B1; Aged; Antioxidants; beta Carotene; Carotenoids; Chronic Disease; DNA; DNA Adducts; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Testosterone; Vitamin E; Vitamins

1997
p53 mutations, chronic hepatitis B virus infection, and aflatoxin exposure in hepatocellular carcinoma in Taiwan.
    Cancer research, 1997, Aug-15, Volume: 57, Issue:16

    Topics: Aflatoxin B1; Biomarkers, Tumor; Carcinoma, Hepatocellular; DNA Adducts; DNA, Neoplasm; Female; Genes, p53; Genetic Markers; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Point Mutation

1997
An intercalation inhibitor altering the target selectivity of DNA damaging agents: synthesis of site-specific aflatoxin B1 adducts in a p53 mutational hotspot.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Sep-02, Volume: 94, Issue:18

    Topics: Aflatoxin B1; Binding Sites; Carcinogens; Carcinoma, Hepatocellular; DNA Damage; Humans; Liver Neoplasms; Mutagenesis, Site-Directed; Mutation; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1997
[Synergism of three risk factors in hepatocellular carcinogenicity].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1996, Volume: 30, Issue:5

    Topics: Adult; Aflatoxin B1; Carcinoma, Hepatocellular; DNA, Viral; Female; Hepacivirus; Hepatitis B virus; Humans; Liver Neoplasms; Male; Middle Aged; Risk Factors; RNA, Viral

1996
Dissimilarity in aflatoxin dose-response relationships between DNA adduct formation and development of preneoplastic foci in rat liver.
    Chemico-biological interactions, 1997, Oct-24, Volume: 106, Issue:3

    Topics: Administration, Oral; Aflatoxin B1; Animals; Body Weight; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Guanine; Liver; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344

1997
Monitoring of aflatoxin exposure by biomarkers.
    The Journal of toxicological sciences, 1998, Volume: 23 Suppl 2

    Topics: Aflatoxin B1; Biomarkers; Carcinogens; Environmental Monitoring; Genes, p53; Humans; Liver Neoplasms; Serum Albumin; Thailand

1998
Different frequencies of p53 codon-249 hot-spot mutations in hepatocellular carcinomas in Jiang-su province of China.
    International journal of cancer, 1999, Jul-19, Volume: 82, Issue:2

    Topics: Adult; Aflatoxin B1; Aged; Carcinoma, Hepatocellular; China; Cluster Analysis; DNA Mutational Analysis; DNA, Neoplasm; Female; Food Contamination; Genes, p53; Humans; Liver Neoplasms; Male; Middle Aged; Mutation; Retrospective Studies

1999
Evidence that mutational activation of the ras genes may not be involved in aflatoxin B(1)-induced human hepatocarcinogenesis, based on sequence analysis of the ras and p53 genes.
    Molecular carcinogenesis, 1999, Volume: 26, Issue:2

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Codon; Gene Expression Regulation, Neoplastic; Genes, p53; Genes, ras; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Mutation; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Sequence Analysis, DNA

1999
Does aflatoxin B1 play a role in the etiology of hepatocellular carcinoma in the United States?
    Nutrition and cancer, 1999, Volume: 35, Issue:1

    Topics: Adult; Aflatoxin B1; Aged; Carcinogens; Carcinoma, Hepatocellular; DNA Primers; Female; Hepacivirus; Hepatitis B virus; Humans; Immunohistochemistry; Liver Neoplasms; Male; Middle Aged; Polymerase Chain Reaction; Tumor Suppressor Protein p53; United States

1999
[Sequence alterations in p53 gene of hepatocellular carcinoma from high aflatoxin risk area in Guangxi].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1997, Volume: 19, Issue:1

    Topics: Adult; Aflatoxin B1; Carcinoma, Hepatocellular; Female; Food Microbiology; Genes, p53; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Middle Aged; Point Mutation; Tumor Suppressor Protein p53; Zea mays

1997
A comparison of apoptosis and necrosis induced by hepatotoxins in HepG2 cells.
    Toxicology and applied pharmacology, 2000, May-01, Volume: 164, Issue:3

    Topics: Adenosine Triphosphate; Aflatoxin B1; Apoptosis; Carbazoles; Carcinogens; DNA Damage; DNA Fragmentation; Hepatoblastoma; Humans; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Liver Neoplasms; Microscopy, Electron; Necrosis; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2000
Reduction of aflatoxin B(1) adduct biomarkers by oltipraz in the tree shrew (Tupaia belangeri chinensis).
    Cancer letters, 2000, Jun-01, Volume: 154, Issue:1

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antiviral Agents; Biomarkers; Chromatography, High Pressure Liquid; DNA Adducts; Female; Hepatitis B virus; Humans; Liver Neoplasms; Male; Pyrazines; Radioimmunoassay; Thiones; Thiophenes; Time Factors; Tupaiidae

2000
Mutations in the p53 tumor suppressor gene in tree shrew hepatocellular carcinoma associated with hepatitis B virus infection and intake of aflatoxin B1.
    Gene, 2000, Jun-13, Volume: 251, Issue:1

    Topics: Aflatoxin B1; Amino Acid Sequence; Animals; Base Sequence; Carcinoma, Hepatocellular; Cloning, Molecular; Disease Models, Animal; DNA Mutational Analysis; DNA, Complementary; Genes, Tumor Suppressor; Hepatitis B; Hepatitis B virus; Liver; Liver Neoplasms; Molecular Sequence Data; Mutation; Point Mutation; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Tumor Suppressor Protein p53; Tupaiidae

2000
[Hepatitis B virus infection and aflatoxin exposure in the development of primary liver cancer].
    Zhonghua yi xue za zhi, 1998, Volume: 78, Issue:5

    Topics: Adult; Aflatoxin B1; Case-Control Studies; China; Hepatitis B; Humans; Liver Neoplasms; Male; Middle Aged; Prevalence; Prospective Studies; Random Allocation

1998
Activation of the insulin-like growth factor II transcription by aflatoxin B1 induced p53 mutant 249 is caused by activation of transcription complexes; implications for a gain-of-function during the formation of hepatocellular carcinoma.
    Oncogene, 2000, Aug-03, Volume: 19, Issue:33

    Topics: Aflatoxin B1; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cell Line, Transformed; DNA-Binding Proteins; Drosophila; Electrophoresis, Polyacrylamide Gel; Gene Expression; Hepatitis B Antigens; Humans; Insulin-Like Growth Factor II; Liver Neoplasms; Mutagenesis; Mutagens; Promoter Regions, Genetic; Sp1 Transcription Factor; TATA-Box Binding Protein; Trans-Activators; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Viral Regulatory and Accessory Proteins

2000
[Molecular aspects of hepatocellular carcinoma].
    Zentralblatt fur Chirurgie, 2000, Volume: 125, Issue:7

    Topics: Adult; Aflatoxin B1; Age Factors; Alcoholism; Animals; Carcinoma, Hepatocellular; Child; Cohort Studies; DNA; DNA Repair; Enzyme Activation; Genes, p53; Growth Substances; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Marmota; Mice; Mice, Transgenic; Middle Aged; Mutation; Risk Factors; Telomerase

2000
p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology, and human risk assessment.
    Annals of the New York Academy of Sciences, 2000, Volume: 919

    Topics: Aflatoxin B1; Carcinogens; DNA Mutational Analysis; Genes, p53; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Mutagens; Neoplasms; Oncogenes; Risk Assessment; Skin Neoplasms; Sunlight

2000
Inhibition of ebselen on aflatoxin B(1)-induced hepatocarcinogenesis in Fischer 344 rats.
    Carcinogenesis, 2000, Volume: 21, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aflatoxin B1; alpha-Fetoproteins; Animals; Anticarcinogenic Agents; Antioxidants; Azoles; Deoxyguanosine; DNA Adducts; gamma-Glutamyltransferase; Glutathione Transferase; Isoenzymes; Isoindoles; Liver; Liver Neoplasms; Male; Organoselenium Compounds; Rats; Rats, Inbred F344; Reactive Oxygen Species; RNA, Messenger; Transcription, Genetic

2000
Profile of hepatocellular carcinoma in India: an insight into the possible etiologic associations.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:6

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; DNA, Viral; Female; Genes, p53; Hepacivirus; Hepatitis Antibodies; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis C; Humans; India; Liver Neoplasms; Male; Middle Aged; Risk Factors; RNA, Viral

2001
CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1.
    Molecular carcinogenesis, 2001, Volume: 31, Issue:2

    Topics: Adult; Aflatoxin B1; Aged; beta Catenin; Carcinoma, Hepatocellular; Codon; Cytoskeletal Proteins; DNA Mutational Analysis; Exons; Female; Genes, p53; Humans; Immunohistochemistry; Infant; Liver Neoplasms; Male; Middle Aged; Mutation; Polymorphism, Single-Stranded Conformational; Signal Transduction; Trans-Activators

2001
Differential effects of acetaminophen pretreatment on hepatic aflatoxin B(1)-DNA binding, cellular proliferation, and aflatoxin B1-induced hepatic foci in rats and hamsters.
    Cancer letters, 2001, Sep-20, Volume: 170, Issue:2

    Topics: Acetaminophen; Aflatoxin B1; Analgesics, Non-Narcotic; Animals; Cell Division; Cricetinae; DNA; Glutathione; Glutathione Transferase; Liver Neoplasms; Male; Rats; Rats, Inbred F344

2001
Genetic polymorphisms of glutathione S-transferases M1 and T1 associated with susceptibility to aflatoxin-related hepatocarcinogenesis among chronic hepatitis B carriers: a nested case-control study in Taiwan.
    Carcinogenesis, 2001, Volume: 22, Issue:8

    Topics: Adult; Aflatoxin B1; Carrier State; Case-Control Studies; Female; Genetic Predisposition to Disease; Glutathione Transferase; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Taiwan

2001
Aflatoxins and fumonisins in corn from the high-incidence area for human hepatocellular carcinoma in Guangxi, China.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:8

    Topics: Aflatoxin B1; Aflatoxins; Carboxylic Acids; Carcinoma, Hepatocellular; China; Food Contamination; Fumonisins; Fusarium; Humans; Incidence; Liver Neoplasms; Mycotoxins; Safety; Zea mays

2001
Associations of plasma aflatoxin B1-albumin adduct level with plasma selenium level and genetic polymorphisms of glutathione S-transferase M1 and T1.
    Nutrition and cancer, 2000, Volume: 38, Issue:2

    Topics: Adult; Aflatoxin B1; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Diet; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Female; Genetic Predisposition to Disease; Genotype; Glutathione Transferase; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Selenium; Serum Albumin; Sex Factors; Spectrophotometry, Atomic; Taiwan

2000
Identification of homozygous deletions at chromosome 16q23 in aflatoxin B1 exposed hepatocellular carcinoma.
    Oncogene, 2001, Aug-23, Volume: 20, Issue:37

    Topics: Aflatoxin B1; Alleles; Carcinogens; Carcinoma, Hepatocellular; Chromosome Deletion; Chromosome Mapping; Chromosomes, Human, Pair 16; Exons; Flow Cytometry; Genes, p53; Genotype; Homozygote; Humans; Liver Neoplasms; Loss of Heterozygosity; Microsatellite Repeats; Models, Genetic; Mutation; RNA, Messenger; Tumor Cells, Cultured

2001
International trends and patterns of primary liver cancer.
    International journal of cancer, 2001, Oct-15, Volume: 94, Issue:2

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Cholangiocarcinoma; Female; Hepatitis C, Chronic; Humans; Incidence; Liver Neoplasms; Male; Registries; Time Factors

2001
[The relationship between cyanotoxin (microcystin, MC) in pond-ditch water and primary liver cancer in China].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2001, Volume: 23, Issue:2

    Topics: Aflatoxin B1; Animals; Animals, Genetically Modified; Carcinoma, Hepatocellular; Child; China; Fresh Water; Glutathione Transferase; Hepatectomy; Humans; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Microcystins; Peptides, Cyclic; Rats; Rats, Inbred F344; Trans-Activators; Viral Regulatory and Accessory Proteins

2001
[p53 gene mutation in hepatocellular carcinoma].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1998, Volume: 36, Issue:9

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; DNA Mutational Analysis; DNA, Neoplasm; Environmental Exposure; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Mutation; Polymorphism, Single-Stranded Conformational; Tumor Suppressor Protein p53

1998
Role of the multidrug resistance protein 1 gene in the carcinogenicity of aflatoxin B1: investigations using mrp1-null mice.
    Toxicology, 2002, Feb-28, Volume: 171, Issue:2-3

    Topics: Aflatoxin B1; Animals; Carcinogens; DNA-Binding Proteins; Genes, MDR; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein

2002
Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol.
    Carcinogenesis, 2002, Volume: 23, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Disease Models, Animal; Female; Indoles; Liver; Liver Neoplasms; Mammary Neoplasms, Experimental; Mutagens; Neoplasms; Rats; Rats, Sprague-Dawley; Time Factors

2002
Enhanced spontaneous and aflatoxin-induced liver tumorigenesis in xeroderma pigmentosum group A gene-deficient mice.
    Carcinogenesis, 2002, Volume: 23, Issue:4

    Topics: Aflatoxin B1; Animals; Apoptosis; Carcinogens; DNA-Binding Proteins; Female; Hepatocytes; Heterozygote; Homozygote; Liver Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Transgenic; S Phase; Skin Neoplasms; Time Factors; Xeroderma Pigmentosum Group A Protein

2002
The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, May-14, Volume: 99, Issue:10

    Topics: Aflatoxin B1; Bacteriophage M13; Carcinoma, Hepatocellular; DNA Adducts; DNA, Neoplasm; DNA, Viral; Guanine; Humans; Liver Neoplasms; Molecular Structure; Mutagenesis; Mutagens; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2002
Epidemiology, risk factors, and natural history of hepatocellular carcinoma.
    Annals of the New York Academy of Sciences, 2002, Volume: 963

    Topics: Aflatoxin B1; Alcohols; Carcinoma, Hepatocellular; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Liver Neoplasms; Risk Factors; Viral Hepatitis Vaccines

2002
[Aflatoxins and primary liver cancer--a population based case-control study].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1992, Volume: 26, Issue:6

    Topics: Aflatoxin B1; Aflatoxin M1; Case-Control Studies; China; Female; Food Contamination; Hepatitis B; Humans; Liver Neoplasms; Logistic Models; Male; Oryza; Plant Oils; Risk Factors

1992
Low frequency of p53 gene mutation in tumors induced by aflatoxin B1 in nonhuman primates.
    Cancer research, 1992, Feb-15, Volume: 52, Issue:4

    Topics: Adenoma, Bile Duct; Aflatoxin B1; Animals; Base Sequence; Bile Duct Neoplasms; Bone Neoplasms; Carcinoma; DNA, Neoplasm; Exons; Genes, p53; Hemangioendothelioma; Introns; Liver Neoplasms; Liver Neoplasms, Experimental; Macaca fascicularis; Macaca mulatta; Molecular Sequence Data; Mutagenesis; Neoplasms, Experimental; Oligodeoxyribonucleotides; Osteosarcoma; Polymerase Chain Reaction

1992
Aflatoxin and hepatocellular carcinoma: a useful paradigm for environmentally induced carcinogenesis.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:3

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Confounding Factors, Epidemiologic; Cytochrome P-450 Enzyme System; Genes, p53; Humans; Liver Neoplasms; Mutation; Smoking

1992
Risk assessment for aflatoxin B1: a modeling approach.
    Risk analysis : an official publication of the Society for Risk Analysis, 1992, Volume: 12, Issue:4

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; China; Dose-Response Relationship, Drug; Female; Hepatitis B virus; Humans; Liver Neoplasms; Male; Models, Biological; Models, Statistical; Risk Factors

1992
Antimutagenic effect of eight natural foods on moldy foods in a high liver cancer incidence area.
    Mutation research, 1992, May-01, Volume: 279, Issue:1

    Topics: Aflatoxin B1; Antimutagenic Agents; China; Food; Liver Neoplasms; Mutagenicity Tests; Mycotoxins; Salmonella typhimurium

1992
Aflatoxin B1 DNA adducts in smeared tumor tissue from patients with hepatocellular carcinoma.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:5

    Topics: Adult; Aflatoxin B1; Aged; Aged, 80 and over; alpha-Fetoproteins; Carcinoma, Hepatocellular; DNA; DNA Adducts; Female; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Middle Aged; Phenylenediamines

1992
[The aflatoxins and liver cancer in Guangxi, China].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1992, Volume: 26, Issue:3

    Topics: Aflatoxin B1; Aflatoxin M1; Arachis; China; Female; Humans; Liver Neoplasms; Male; Plant Oils; Regression Analysis; Zea mays

1992
Liver DNA adducts in methyl-deficient rats administered a single dose of aflatoxin B1.
    Carcinogenesis, 1992, Volume: 13, Issue:7

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Biotransformation; Choline Deficiency; Diet; DNA; DNA Repair; Liver; Liver Neoplasms; Liver Regeneration; Male; Methionine; Precancerous Conditions; Rats; Rats, Inbred F344

1992
Analysis of ras gene mutations in rainbow trout liver tumors initiated by aflatoxin B1.
    Molecular carcinogenesis, 1991, Volume: 4, Issue:2

    Topics: Adenoma, Bile Duct; Aflatoxin B1; Aflatoxins; Alleles; Animals; Base Sequence; Cloning, Molecular; Exons; Gene Expression Regulation; Genes, ras; Liver Neoplasms; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutagenesis; Nucleic Acid Hybridization; Oligonucleotide Probes; Plasmids; Polymerase Chain Reaction; Species Specificity; Trout

1991
Expression of immunoreactive glutathione S-transferases in hepatic neoplasms induced by aflatoxin B1 or 1,2-dimethylbenzanthracene in rainbow trout (Oncorhynchus mykiss).
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Blotting, Western; Carcinogens; Electrophoresis, Polyacrylamide Gel; Eosine Yellowish-(YS); Gene Expression; Glutathione Transferase; Liver; Liver Neoplasms; Trout

1990
Aflatoxin B1-DNA adducts and hepatitis B virus antigens in hepatocellular carcinoma and non-tumorous liver tissue.
    Carcinogenesis, 1991, Volume: 12, Issue:12

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; DNA; Female; Fluorescent Antibody Technique; Hepatitis B Antigens; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Staining and Labeling; Trans-Activators; Viral Regulatory and Accessory Proteins

1991
Glutathione S-transferase mu in human lymphocyte and liver: role in modulating formation of carcinogen-derived DNA adducts.
    Carcinogenesis, 1991, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aflatoxin B1; Aged; Aged, 80 and over; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chromatography, High Pressure Liquid; Cytosol; Dinitrochlorobenzene; DNA; Female; Glutathione Transferase; Humans; Liver; Liver Neoplasms; Lymphocytes; Male; Middle Aged; Polymorphism, Genetic; Pyrimidines; Stilbenes

1991
[The co-mutagenic effect of metabolic extracts of fungi grown on the main grain in high incidence liver cancer areas--Fusui County].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1991, Volume: 25, Issue:5

    Topics: Aflatoxin B1; Aspergillus; Aspergillus flavus; Edible Grain; Food Microbiology; Humans; Liver Neoplasms; Mutagenicity Tests; Mycotoxins

1991
The isolation and culture of DHBV-infected embryo and duckling hepatocytes and the effect of aflatoxin B1 or irradiation on these cells.
    British journal of cancer, 1991, Volume: 63, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Blood Proteins; Cells, Cultured; DNA, Viral; Ducks; Embryo, Nonmammalian; Hepatitis B Virus, Duck; Liver; Liver Neoplasms; Liver Neoplasms, Experimental

1991
Activation of the hepatocarcinogen aflatoxin B1 by forms of human hepatic cytochromes P-450: some do and some don't.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Humans; Liver Neoplasms

1991
Hepatic neoplasms in aflatoxin B1-treated, congenital duck hepatitis B virus-infected, and virus-free pekin ducks.
    Cancer research, 1990, Jul-01, Volume: 50, Issue:13

    Topics: Aflatoxin B1; Aflatoxins; Amyloidosis; Animals; Carcinoma, Hepatocellular; DNA, Neoplasm; DNA, Viral; Ducks; Female; gamma-Glutamyltransferase; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Liver Diseases; Liver Neoplasms; Ovarian Neoplasms; Splenic Diseases

1990
Contribution of aflatoxin B1 and hepatitis B virus infection in the induction of liver tumors in ducks.
    Cancer research, 1990, Apr-01, Volume: 50, Issue:7

    Topics: Aflatoxin B1; Aflatoxins; Animals; DNA; DNA Damage; DNA, Viral; Ducks; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms; Liver Neoplasms, Experimental; Restriction Mapping; Survival Analysis

1990
Glutathione S-transferase localization in aflatoxin B1-treated rat livers.
    Carcinogenesis, 1990, Volume: 11, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cells, Cultured; Gene Expression; Glutathione Transferase; Immunohistochemistry; Liver; Liver Neoplasms; Macromolecular Substances; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Reference Values

1990
Mutations in the Ha-ras proto-oncogene in spontaneous and chemically induced liver tumours of the CF1 mouse.
    Carcinogenesis, 1990, Volume: 11, Issue:10

    Topics: Aflatoxin B1; Aflatoxins; Animals; Base Sequence; Carcinogens; Dieldrin; DNA, Neoplasm; Genes, ras; Liver Neoplasms; Mice; Mice, Inbred Strains; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Phenobarbital; Polymerase Chain Reaction

1990
A single dose-response effect of aflatoxin B1 on rapid liver cancer induction in two strains of rats.
    International journal of cancer, 1990, Oct-15, Volume: 46, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Alanine Transaminase; Animals; Body Weight; Dose-Response Relationship, Drug; Liver Neoplasms; Male; Organ Size; Rats; Rats, Inbred Strains

1990
Association of reduction of AFB1-induced liver tumours by antioxidants with increased activity of microsomal enzymes.
    The Indian journal of medical research, 1990, Volume: 92

    Topics: Aflatoxin B1; Aflatoxins; Animals; Antioxidants; Carcinogens; Liver Neoplasms; Male; Microsomes; Rats; Rats, Inbred Strains

1990
A new method for the quantitation of aflatoxin M1 in urine by high performance liquid chromatography and its application to the etiologic study of hepatoma.
    Biomedical chromatography : BMC, 1990, Volume: 4, Issue:2

    Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Carcinoma, Hepatocellular; China; Chromatography, High Pressure Liquid; Humans; Liver Neoplasms; Microchemistry; Quality Control; Tupaia

1990
Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:12

    Topics: Aflatoxin B1; Aflatoxins; Biotransformation; Carcinoma, Hepatocellular; Cell Line; Cytochrome P-450 Enzyme System; DNA, Neoplasm; Gene Expression; Genetic Vectors; Humans; Kinetics; Liver; Liver Neoplasms; Microsomes, Liver; Protein Binding; Tumor Cells, Cultured; Vaccinia virus

1990
Protective activity of different hepatic cytosolic glutathione S-transferases against DNA-binding metabolites of aflatoxin B1.
    Toxicology and applied pharmacology, 1990, Sep-15, Volume: 105, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Carcinoma, Hepatocellular; Cytosol; DNA; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Isoenzymes; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Microsomes, Liver; Polychlorinated Biphenyls; Rats; Sodium Dodecyl Sulfate; Trout

1990
Ovarian function during aflatoxin B1-induced hepatocarcinogenesis in the rat.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 53, Issue:2

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Body Weight; Dietary Proteins; Estradiol; Female; Genitalia, Female; Gonads; Liver Neoplasms; Liver Neoplasms, Experimental; Ovary; Progesterone; Rats; Rats, Inbred Strains

1986
Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Adipates; Aflatoxin B1; Aflatoxins; Aldrin; Animals; Benzidines; Biological Availability; Carbon Tetrachloride; Carcinogens; Cell Division; Circadian Rhythm; DDT; Diethylhexyl Phthalate; DNA; DNA Replication; Female; Hexachlorocyclohexane; Isomerism; Liver; Liver Neoplasms; Male; Mice; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Thioacetamide

1987
Hepatitis B virus, aflatoxins, and hepatocellular carcinoma in southern Guangxi, China.
    Cancer research, 1989, May-01, Volume: 49, Issue:9

    Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Aged; Carcinoma, Hepatocellular; China; Female; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Middle Aged

1989
Aflatoxin B1 formamidopyrimidine adducts in human hepatocarcinogenesis: a preliminary report.
    Gastroenterology, 1989, Volume: 97, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Antibodies, Monoclonal; Carcinogens; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Humans; Immunoblotting; Liver Neoplasms; Pyrimidines

1989
Glutamine synthetase heterogeneous expression as a marker for the cellular lineage of preneoplastic and neoplastic liver populations.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: 2-Acetylaminofluorene; Adenoma; Aflatoxin B1; Aflatoxins; Animals; Biomarkers, Tumor; Diethylnitrosamine; Glutamate-Ammonia Ligase; Immunoenzyme Techniques; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Reference Values

1989
Immunoassay procedures to detect exposure to aflatoxin B1 and benzo(a)pyrene in animals and man at the DNA level.
    International archives of occupational and environmental health, 1988, Volume: 60, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Hepatocellular; DNA; Enzyme-Linked Immunosorbent Assay; Humans; Liver; Liver Neoplasms; Lung; Male; Rats; Rats, Inbred Strains

1988
Cytotoxicity of halogenated alkanes in primary cultures of rat hepatocytes from normal, partial hepatectomized, and preneoplastic/neoplastic liver.
    Toxicology and applied pharmacology, 1985, Sep-15, Volume: 80, Issue:2

    Topics: Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Cell Survival; Cells, Cultured; gamma-Glutamyltransferase; Hepatectomy; Hydrocarbons, Halogenated; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Maleates; Proadifen; Rats; Rats, Inbred F344

1985
Dose-related inhibition of aflatoxin B1 induced hepatocarcinogenesis by the phenolic antioxidants, butylated hydroxyanisole and butylated hydroxytoluene.
    Carcinogenesis, 1986, Volume: 7, Issue:7

    Topics: Aflatoxin B1; Aflatoxins; Animals; Anisoles; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; gamma-Glutamyltransferase; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344

1986
Increased UDP-glucuronyltransferase and gamma-glutamyltranspeptidase in enzyme-altered rat liver lesions produced by low doses of aflatoxin B1.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1986, Volume: 51, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Animals; gamma-Glutamyltransferase; Glucuronosyltransferase; Liver; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred Strains

1986
The effects of dietary fat and selenium on the development of preneoplastic lesions in rat liver.
    Nutrition and cancer, 1986, Volume: 8, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Dietary Fats, Unsaturated; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Lipid Metabolism; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; Selenium

1986
Influence of dietary fat and selenium in initiation and promotion of aflatoxin B1-induced preneoplastic foci in rat liver.
    Carcinogenesis, 1987, Volume: 8, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Dietary Fats; Eating; Enzyme Induction; gamma-Glutamyltransferase; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; Selenium

1987
Risk factors for hepatocellular carcinoma in Guangxi, People's Republic of China.
    National Cancer Institute monograph, 1985, Volume: 69

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; China; Food Contamination; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Cirrhosis; Liver Neoplasms; Risk

1985
Interaction of aflatoxin and hepatitis B virus in the pathogenesis of hepatocellular carcinoma.
    Life sciences, 1986, Oct-06, Volume: 39, Issue:14

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; DNA, Neoplasm; DNA, Viral; Hepatitis B; Hepatitis B virus; Humans; Liver Neoplasms; Models, Biological

1986
[Respective roles of aflatoxin and hepatitis B in the etiology of primary cancer of the liver in man].
    Bulletin de l'Academie nationale de medecine, 1986, Volume: 170, Issue:6

    Topics: Adenoma, Bile Duct; Adolescent; Adult; Aflatoxin B1; Aflatoxins; Age Factors; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Child; Child, Preschool; Female; Hepatitis B; Humans; Liver Neoplasms; Male; Middle Aged; Sex Factors

1986
Aflatoxin exposure measured by urinary excretion of aflatoxin B1-guanine adduct and hepatitis B virus infection in areas with different liver cancer incidence in Kenya.
    Cancer research, 1987, Jul-01, Volume: 47, Issue:13

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; DNA Damage; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Kenya; Liver Neoplasms; Male; Sex Factors

1987
Aflatoxin, viral hepatitis and primary liver cancer.
    Journal of medicine, 1987, Volume: 18, Issue:1

    Topics: Adenoma, Bile Duct; Aflatoxin B1; Aflatoxins; Carcinogens; Carcinoma, Hepatocellular; Female; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Middle Aged

1987
Interindividual differences in the activation of two hepatic carcinogens to mutagens by human liver.
    Human toxicology, 1986, Volume: 5, Issue:1

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Alkaline Phosphatase; Aryl Hydrocarbon Hydroxylases; Aspartate Aminotransferases; Bilirubin; Biotransformation; Carcinogens; Humans; In Vitro Techniques; Liver; Liver Neoplasms; Mutagenicity Tests; Subcellular Fractions

1986
Aflatoxin B1 binding to plasma albumin and liver DNA upon chronic administration to rats.
    Carcinogenesis, 1986, Volume: 7, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; DNA; Dose-Response Relationship, Drug; Feces; Half-Life; Liver; Liver Neoplasms; Male; Protein Binding; Rats; Rats, Inbred Strains; Serum Albumin; Time Factors; Tritium

1986
Differential effects of transforming growth factor-beta on proliferation of normal and malignant rat liver epithelial cells in culture.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Growth Inhibitors; Liver; Liver Neoplasms; Microscopy, Electron; Peptides; Rats; Transforming Growth Factors

1986
Identification of an activated c-Ki-ras oncogene in rat liver tumors induced by aflatoxin B1.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:24

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Gene Expression Regulation; GTP-Binding Proteins; Liver Neoplasms; Mice; Proto-Oncogene Proteins; Proto-Oncogenes; Rats; Transfection

1986
Relative contribution of dietary protein level and aflatoxin B1 dose in generation of presumptive preneoplastic foci in rat liver.
    Journal of the National Cancer Institute, 1987, Volume: 78, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Caseins; Dietary Proteins; Dose-Response Relationship, Drug; Liver Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344

1987
[Experimental study on selenic blockage of primary hepatocarcinoma induced by aflatoxin B1 in rats].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1987, Volume: 21, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Female; Liver Neoplasms; Male; Rats; Rats, Inbred Strains; Selenium

1987
Effect of (+)-catechin, dimethyl sulfoxide and ethanol on the microsome-mediated metabolism of two hepatocarcinogens, N-nitrosodimethylamine and aflatoxin B1.
    IARC scientific publications, 1987, Issue:84

    Topics: Aflatoxin B1; Aflatoxins; Animals; Catechin; Cricetinae; Dimethyl Sulfoxide; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Ethanol; Liver Neoplasms; Microsomes, Liver

1987
Conjugation of model substrates or microsomally-activated aflatoxin B1 with reduced glutathione, catalysed by cytosolic glutathione-S-transferases in livers of rats, mice and guinea pigs.
    Biochemical pharmacology, 1987, Dec-15, Volume: 36, Issue:24

    Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Bridged Bicyclo Compounds; Cytosol; Dinitrochlorobenzene; Glutathione; Glutathione Transferase; Guinea Pigs; Isoenzymes; Liver; Liver Neoplasms; Mice; Microsomes, Liver; Nitrobenzenes; Precancerous Conditions; Rats

1987
In vitro binding of aflatoxin B1 and 2-acetylaminofluorene to rat, mouse and human hepatocyte DNA: the relationship of DNA binding to carcinogenicity.
    Carcinogenesis, 1988, Volume: 9, Issue:5

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Cells, Cultured; DNA; Female; Humans; Liver; Liver Neoplasms; Male; Mice; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity

1988
Liver foci formation during aflatoxin B1 carcinogenesis in the rat.
    Annals of the New York Academy of Sciences, 1988, Volume: 534

    Topics: Aflatoxin B1; Aflatoxins; Algorithms; Animals; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Time Factors

1988
Comparative effect of dietary butylated hydroxyanisole and beta-naphthoflavone on aflatoxin B1 metabolism, DNA adduct formation, and carcinogenesis in rainbow trout.
    Carcinogenesis, 1988, Volume: 9, Issue:10

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; beta-Naphthoflavone; Butylated Hydroxyanisole; Carcinogens; Cell Nucleus; Diet; DNA; Flavonoids; Liver; Liver Neoplasms; Salmonidae; Trout

1988
Do aflatoxin-DNA adduct measurements in humans provide accurate data for cancer risk assessment?
    IARC scientific publications, 1988, Issue:89

    Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies, Monoclonal; Chromatography, Affinity; DNA; Environmental Monitoring; Ethoxyquin; Humans; Liver Neoplasms; Male; Rats; Rats, Inbred F344

1988
Detection of exposure to aflatoxin in an African population.
    IARC scientific publications, 1988, Issue:89

    Topics: Aflatoxin B1; Aflatoxins; Africa; DNA; Environmental Monitoring; Humans; Liver Neoplasms

1988
Aflatoxin B1 induced hepatic neoplasia in Great Lakes coho salmon.
    Bulletin of environmental contamination and toxicology, 1988, Volume: 41, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Animals; Embryo, Nonmammalian; Environmental Monitoring; Liver Neoplasms; Microinjections; Salmon

1988
Covalent binding of aflatoxin B1 to liver DNA in rats pretreated with ethanol.
    Experientia, 1985, Oct-15, Volume: 41, Issue:10

    Topics: Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Cocarcinogenesis; DNA; Ethanol; Liver; Liver Neoplasms; Rats; Rats, Inbred F344

1985
Oil refinery effluents: evidence of cocarcinogenic activity in the trout embryo microinjection assay.
    Journal of the National Cancer Institute, 1985, Volume: 75, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Bone and Bones; Carcinogens, Environmental; Cocarcinogenesis; Fuel Oils; Industrial Waste; Liver Neoplasms; Methylnitronitrosoguanidine; Microinjections; Mutagenicity Tests; Mutagens; Petroleum; Rats; Trout; Water Pollutants; Water Pollutants, Chemical

1985