aflatoxin b1 has been researched along with Experimental Hepatoma in 244 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 84 (34.43) | 18.7374 |
| 1990's | 101 (41.39) | 18.2507 |
| 2000's | 37 (15.16) | 29.6817 |
| 2010's | 19 (7.79) | 24.3611 |
| 2020's | 3 (1.23) | 2.80 |
| Authors | Studies |
|---|---|
| Chhonker, SK; Koiri, RK; Naik, RA; Rawat, D; Shrivastava, S | 1 |
| Chhonker, SK; Koiri, RK; Naik, RA; Rawat, D | 1 |
| Chhonker, SK; Koiri, RK; Rawat, D | 1 |
| Auerbach, SS; Mav, D; Merrick, BA; Phadke, DP; Shah, RR; Stiegelmeyer, SM; Tice, RR | 1 |
| Chen, Z; Ji, J; Li, J; Wang, H; Yang, L | 1 |
| Andrews, LS; Bachman, AN; Boogaard, PJ; Cadet, J; Embry, MR; Farmer, PB; Himmelstein, MW; Jarabek, AM; Kim, JH; Martin, EA; Mauthe, RJ; Persaud, R; Pottenger, LH; Preston, RJ; Schoeny, R; Skare, J; Swenberg, JA; Williams, GM; Zeiger, E; Zhang, F | 1 |
| Baxter, VK; Egner, PA; Groopman, JD; Johnson, NM; Kensler, TW; Roebuck, BD; Sporn, MB; Sutter, TR; Wible, RS | 1 |
| Olden, K; Vulimiri, SV | 1 |
| Eaton, DL; Schaupp, CM | 1 |
| Maurya, BK; Singh, KB; Trigun, SK | 1 |
| Jarukamjorn, K; Punvittayagul, C; Suwannakul, N; Wongpoomchai, R | 1 |
| Goh, LK; Sabapathy, K; Teoh, WW; Tong, WM; Vijayaraghavan, A; Xie, M; Yaligar, J | 1 |
| Maurya, BK; Trigun, SK | 1 |
| Gelderblom, WC; Lin, S; Mitchell, NJ; Phillips, TD; Qian, G; Riley, RT; Su, J; Tang, L; Wang, JS; Xue, KS | 1 |
| Chao, PY; Chen, CM; Chen, YH; Hsieh, LL; Hsu, CY; Hu, SP | 1 |
| Chen, SY; Chen, YM; Chou, TY; Darbha, R; Hsieh, LL; Hung, JH; Liu, HH; Liu, SP; Tsai, TF; Ueng, YF; Yen, CH | 1 |
| Brown, DL; Cullen, JM; Foley, JF; French, JE; Kissling, GE; Marion, PL; Parron, VI; Rizzo, J | 1 |
| Luka, Z; Mato, JM; Wagner, C | 1 |
| Cao, J; Duan, XX; Hao, YR; Li, Y; Ou, C; Su, JJ; Yang, C; Yang, F; Zhang, JJ | 1 |
| Knudsen, ES; Mayhew, CN; McClendon, AK; Reed, CA; Witkiewicz, A; Yang, X | 1 |
| Dedon, PC; Doernte, AL; Essigmann, JM; Feng, Y; Fiala, JL; Fox, JG; Fry, RC; Lemon, SM; McFaline, JL; Raczynski, AR; Rogers, AB; Schauer, DB; Tannenbaum, SR; Theve, EJ; Weinman, SA; Williams, M | 1 |
| Fukusato, T; Kikuchi, T; Ono, Y; Ubagai, T | 1 |
| David, E; Favaloro, FG; Gribble, GW; Honda, T; Honda, Y; Janosik, T; Lajoie, MJ; Roebuck, BD; Su, X; Sundararajan, C; Yoshizawa, H | 1 |
| Boorman, GA; Bradford, BU; Jeannot, E; Kosyk, O; Melnyk, SB; Pogribny, IP; Rusyn, I; Shymoniak, S; Tryndyak, V; Tumurbaatar, B; Weinman, SA | 1 |
| Williams, DE | 1 |
| Aggarwal, PK; Behare, PV; Kumar, A; Kumar, M; Nagpal, R; Singh, B; Verma, V | 1 |
| Chen, L; Chen, XP; Dong, HH; Dong, W; Li, CH; Liang, HF; Wang, HY; Wang, YJ; Xiang, S | 1 |
| Benninghoff, AD; Buchner, CH; Duffy, AM; Hendricks, JD; Orner, GA; Williams, DE | 1 |
| Belloir, C; Guyonnet, D; Le Bon, AM; Siess, MH; Suschetet, M | 1 |
| Ban, KC; Cao, JI; Li, Y; Ou, C; Qin, LL; Qiu, XK; Su, JJ; Yang, C | 1 |
| Ban, KC; Duan, XX; Li, Y; Li, YY; Ou, C; Qin, LL; Su, JJ; Wang, HY; Yan, RQ; Yang, C | 1 |
| Angsubhakorn, S; Nguansangiam, S; Phanwichien, K; Pradermwong, A | 1 |
| Buetow, KH; Evans, AA; Hunter, K; LeVoyer, T; London, WT; McGlynn, KA; Michielli, RA; Roush, J; Shen, FM; Wise, P | 1 |
| Bell, RC; Campbell, TC; Dietert, RR; Golemboski, KA | 1 |
| Ban, KC; Cao, J; Gu, JR; Li, Y; Ou, C; Ou, SJ; Qiu, XK; Su, JJ; Wan, DF; Wei, W; Yang, C; Yue, HF; Zhang, LS | 1 |
| Roebuck, BD | 1 |
| Arnault, I; Auger, J; Bergès, R; Kahane, R; le Bon, AM; Pinnert, MF; Siess, MH; Vernevaut, MF | 1 |
| Emerole, GO; Farombi, EO; Nwankwo, JO | 1 |
| Ban, KC; Duan, XX; Li, Y; Ou, C; Ou, JS; Su, JJ; Yang, C; Yue, HF | 1 |
| Piegorsch, WW; West, RW | 1 |
| Baumgartner, KJ; Bodreddigari, S; Egner, PA; Gribble, GW; Groopman, JD; Honda, T; Kensler, TW; Kwak, MK; Liby, KT; Roebuck, BD; Sporn, MB; Sutter, TR; Yates, MS; Yore, MM | 1 |
| Gallagher, EP | 1 |
| Belloir, C; Le Bon, AM; Siess, MH; Singh, V | 1 |
| Bezençon, C; Cavin, C; Cornaz, R; Guignard, G; Holzhäuser, D; Langouët, S; Marin-Kuan, M; Piguet, D; Schilter, B; Verguet, C | 1 |
| Cao, J; Chen, G; Feng, ZB; Su, JJ | 1 |
| Cao, J; Cui, J; Dai, Z; Duan, X; Kang, X; Li, Y; Liu, Y; Ou, C; Qin, X; Su, J; Yang, C; Yue, H; Zhang, Y | 1 |
| Clark, I; Lewis, RJ; Lin, W; Mackenzie, JW; Rogers, J; Sisler, GE | 1 |
| Bednarz, W; Zawirska, B | 1 |
| Appleton, BS; Campbell, TC | 1 |
| Zawirska, B | 1 |
| Manson, MM | 1 |
| Manson, MM; Smith, AG | 1 |
| Green, JA; Manson, MM; Neal, GE | 1 |
| Avadhani, NG; Bhat, NK; Emeh, JK; Niranjan, BG | 1 |
| Miller, EC; Miller, JA; Moore, MR; Pitot, HC | 1 |
| Loquet, C; Wiebel, FJ | 1 |
| Clark, I; Lin, W; MacKenzie, JW; McCoy, JR | 2 |
| Croy, RG; Essigmann, JM; Wogan, GN | 1 |
| Büchi, GH; Croy, RG; Essigmann, JM; Fowler, KW; Green, CL; Wogan, GN | 1 |
| Han, IW; Yun, TK; Yun, YS | 1 |
| Dix, KM | 1 |
| Bailey, GS; Hendricks, JD; Nixon, JE; Pawlowski, NE; Pereira, CB; Sinnhuber, RO | 1 |
| Metcalfe, CD; Sonstegard, RA | 2 |
| Hall, SD; Lee, AM; Murison, GL | 1 |
| Cullen, JM; Hsieh, DP; Ruebner, BH | 1 |
| Connor, M; Newberne, PM | 1 |
| Novi, AM | 1 |
| Carr, BI; Laishes, BA | 1 |
| Hendricks, JD; Putnam, TP; Sinnhuber, RO | 1 |
| Hendricks, JD; Loveland, PM; Nixon, JE; Pawloswki, NE; Sinnhuber, RO | 1 |
| Gasiorowski, K; Zawirska, B | 1 |
| Angsubhakorn, S; Bhamarapravati, N; Romruen, K; Sahaphong, S | 1 |
| Arora, RG | 1 |
| Imaida, K; Ito, N; Shirai, T; Takano, T; Tatematsu, M | 1 |
| Nixon, JE; Sinnhuber, RO; Whitham, M | 1 |
| Billings, PC; Heidelberger, C; Uwaifo, AO | 1 |
| Bailey, G; Breinholt, V; Dashwood, R; Schimerlik, M | 1 |
| Arbogast, DN; Buhler, DR; Carpenter, HM; Curtis, LR; el-Zahr, C; Hendricks, JD; Miranda, CL; Selivonchick, DP; Zhang, Q | 1 |
| Bannasch, P; Elgas, M; Haberkorn, U; Hacker, HJ; Khoshkhou, NI; Kopp-Schneider, A; Mrozek, M; Radaeva, S; Tolle, T; Zillmann, U | 1 |
| Egner, PA; Kelloff, GJ; Kensler, TW; Primiano, T; Roebuck, BD; Sutter, TR | 1 |
| Arbogast, D; Bailey, G; Breinholt, V; Hendricks, J; Pereira, C | 1 |
| Chemin, I; Chisari, FV; Kirby, GM; Lang, MA; Montesano, R; Wild, CP | 1 |
| Reen, RK; Singh, J; Wiebel, FJ | 1 |
| Arbogast, DN; Bailey, GS; Bjeldanes, LF; Dashwood, RH; Fong, AT; Hendricks, JD | 1 |
| Chen, ZY; Eaton, DL | 1 |
| Cova, L; Duflot, A; Hollstein, M; Mehrotra, R; Montesano, R; Trepo, C | 1 |
| Bailey, GS; Hendricks, JD; Park, DL; Price, RL | 1 |
| Murakami, Y | 1 |
| Kupradinun, P; Rojanapo, W; Tanyakaset, M; Tepsuwan, A | 1 |
| Blanck, A; Gustafsson, JA; Liao, D; Porsch-Hällström, I | 1 |
| Grasl-Kraupp, B; Huber, W; Schulte-Hermann, R; Waldhör, T | 1 |
| Kensler, TW; MacMillan, DL; Maxuitenko, YY; Roebuck, BD | 1 |
| Nyandieka, HS; Wakhisi, J | 1 |
| Groopman, JD; Hasler, J; Junshi, C; Kensler, TW; Wild, CP; Wogan, GN | 1 |
| Bolton, MG; Groopman, JD; Jacobson, LP; Kensler, TW; Maxuitenko, YY; Muñoz, A; Roebuck, BD | 1 |
| Chen, ZY; Eaton, DL; Hulla, JE | 1 |
| Cova, L; Jansen, LA; Montesano, R; Wild, CP | 1 |
| Soman, NR; Wogan, GN | 1 |
| Farmer, PB; Hayes, JD; Judah, DJ; Lamb, JH; Lian, LY; Neal, GE; Roberts, GC; Yang, JC | 1 |
| Larson, PS; McMahon, G; Wogan, GN | 1 |
| Bailey, GS; Carpenter, HM; Hendricks, JD; Mathews, C; Orner, GA; Williams, DE | 1 |
| Gan, YC; Huang, DR; Huang, GH; Su, JJ; Yan, RQ; Yang, C | 1 |
| Iatropoulos, MJ; Williams, GM | 1 |
| Groopman, JD; Kensler, TW; Musser, SM; Scholl, P | 1 |
| Curphey, TJ; Kensler, TW; Maxuitenko, YY; Roebuck, BD | 1 |
| Ellis, EM; Hayes, JD; Ireland, LS; Judah, DJ; Manson, MM; McLellan, LI; McLeod, R; Neal, GE; Pulford, DJ | 1 |
| Curtis, LR; Donohoe, RM; Hendricks, JD; Orner, GA; Williams, DE | 1 |
| Gopalan-Kriczky, P; Hiruma, S; Lotlikar, PD; Qin, GZ; Sato, K; Shinozuka, H | 1 |
| Gopalan-Kriczky, P; Lotlikar, PD; Ning, Y; Qin, G; Su, J | 1 |
| Chisari, FV; Kaplanski, C; Wild, CP | 1 |
| Netke, SP; Niedzwiecki, A; Roomi, MW; Tsao, C | 1 |
| Bhide, SV; Chackradeo, P; Kuttan, R; Lahiri, M; Soni, KB | 1 |
| London, NL; London, WT | 1 |
| Sengstag, C | 1 |
| Dolan, PM; Egner, PA; Gange, SJ; Groopman, JD; Kensler, TW; Muñoz, A; Roebuck, BD; Rogers, AE | 1 |
| Arthur, JR; Ellis, EM; Hayes, JD; Judah, DJ; Manson, MM; McLeod, R; Neal, GE | 1 |
| Arbogast, D; Hendricks, JD; Orner, GA; Williams, DE | 1 |
| Astorg, P; Bergès, R; Gradelet, S; Le Bon, AM; Suschetet, M | 1 |
| Ghebranious, N; Sell, S | 1 |
| Chu, JS; Lee, CC; Lin, JK; Liu, JY; Shew, JY | 1 |
| Bailey, G; Breinholt, V; Dashwood, R; Hayatsu, H; Hendricks, J; Negishi, T | 1 |
| Ellis, EM; Hayes, JD; James, RF; Jernström, B; McLeod, R; Mosialou, E; Neal, GE; Pulford, DJ; Seidegård, J | 1 |
| Ihara, T; Iida, N; Inoue, K; Myoubudani, H; Sugamata, M; Sugiyama, A; Tashiro, F; Ueno, Y | 1 |
| Curphey, TJ; Joyner, HH; Kensler, TW; Libby, AH; MacMillan, DL; Maxuitenko, YY; Roebuck, BD | 1 |
| Ball, HW; Barrett, MC; Clark, HL; Hudson, EA; Judah, DJ; Manson, MM; Neal, GE; Verschoyle, RD | 1 |
| Lotlikar, PD; Ning, Y; Qin, G; Shinozuka, H; Su, J | 1 |
| Bailey, GS; Hendricks, JD; Oganesian, A; Orner, GA; Pereira, CB; Williams, DE | 1 |
| Muthulakshmi, V; Premalatha, B; Sachdanandam, P | 1 |
| Huang, DR; Lotlikar, PD; Qin, GZ; Su, JJ; Yan, RQ; Yang, C | 1 |
| Ban, KC; Li, Y; Qin, LL; Su, JJ; Yan, RQ; Yang, C | 1 |
| Chou, M; Hinton, DM; Sahu, S; Sotomayor, RE; Washington, M | 1 |
| Arbogast, D; Bailey, G; Breinholt, V; Dashwood, R; Hendricks, J; Loveland, P; Pereira, C | 1 |
| Ha, TG; Jang, JJ; Kim, ND; Kim, SG | 1 |
| Premalatha, B; Sachdanandam, P | 2 |
| Campbell, TC; King, JM; Levitsky, DA; Lin, X | 1 |
| Nagy, P; Schaff, Z; Schnur, J; Sebestyén, A; Thorgeirsson, SS | 1 |
| Chanas, SA; Ellis, EM; Hayes, JD; Judah, DJ; Kelly, VP; Manson, MM; McLeod, R; Moffat, GJ; Neal, GE | 1 |
| Beland, FA; Chou, MW; Mikhailova, MV; Nichols, J; Poirier, LA; Warbritton, A | 1 |
| Wogan, GN | 1 |
| Ball, HW; Manson, MM; McLellan, LI; Shepherd, AG | 1 |
| Chou, FP; Hsu, JD; Lee, MJ; Lin, YL; Shiow, SJ; Wang, CJ | 1 |
| Bannasch, P; Burger, V; Hacker, HJ; Kopp-Schneider, A; Li, Y; Radaeva, S | 1 |
| Canivenc-Lavier, MC; Le Bon, AM; Siess, MH; Suschetet, M | 1 |
| Alvarez, ML; Carnovale, CE; Carrillo, MC; Favre, C; Lugano, MC; Monti, JA; Pisani, GB; Scapini, C | 1 |
| Bacon, CW; Carlson, DB; Meredith, FI; Riley, RT; Ross, PF; Spitsbergen, JM; Williams, DE | 1 |
| Liu, J; Ong, CN; Shen, HM; Tan, CE; Wasser, S; Yang, CF | 1 |
| Lotlikar, PD; Ning, Y; Qin, G | 1 |
| Okita, K | 1 |
| Yu, S; Zhao, N; Zi, X | 1 |
| Lin, S; Wang, J; Wang, L | 1 |
| Fujimoto, Y; Hampton, LL; Luo, LD; Thorgeirsson, SS; Wirth, PJ | 1 |
| Akao, M; Gonoi, T; Kishikawa, S; Kuroda, K | 1 |
| Curphey, TJ; Eaton, DL; Groopman, JD; Kensler, TW; Roebuck, BD | 1 |
| Blanck, A; Gustafsson, JA; Lindeskog, P; Lindhe, B; Porsch Hällström, I | 1 |
| Albrecht, R; Boisset, M; Frayssinet, C; Pélissier, MA | 1 |
| Cabonce, MA; Kier, LD; Lilleberg, SL; Raju, NR; Wagner, LM | 2 |
| Campbell, TC; Youngman, LD | 1 |
| Judah, DJ; Mandel, HG; Neal, GE | 1 |
| Mathur, M; Nayak, NC; Rizvi, TA | 4 |
| Davie, JR; Delcuve, GP; Sun, JM | 1 |
| Bailey, G; Chang, YJ; Hendricks, J; Mangold, K; Marien, K; Mathews, C | 1 |
| Duimstra, JR; Hendricks, JD; Nunez, O | 1 |
| Duan, XX; Li, Y; Qin, GZ; Qin, LL; Yan, RQ | 1 |
| Groopman, JD; Kensler, TW; Liu, YL; Roebuck, BD; Rogers, AE | 1 |
| Bell, RC; Campbell, TC; Horio, F; Youngman, LD | 1 |
| Carthew, P; Green, JA; Heuillet, E; Manson, MM; Simpson, JL | 1 |
| DeMatos, P; Egner, PA; Groopman, JD; Kensler, TW; Love-Hunt, A | 1 |
| Qin, GZ | 1 |
| Huff, JE | 1 |
| Judah, DJ; Neal, GE; Olubuyide, IO; Riley, J | 1 |
| Bailey, GS; Dashwood, RH; Fong, AT; Hendricks, JD; Williams, DE | 1 |
| Dominguez, JM; Guénette, A; Paiement, J; Roy, L | 1 |
| Bailey, GS; Dashwood, RH; Fong, AT; Hendricks, JD; Scanlan, RA; Williams, DE | 1 |
| Kato, T; Kobayashi, T; Nakamura, K; Ohtsubo, K; Tashiro, F; Ueno, Y; Yamamura, H | 1 |
| Raisuddin, S; Ray, PK; Singh, KP; Zaidi, SI | 1 |
| Hsu, JD; Lin, JK; Wang, CJ | 1 |
| Gerbracht, U; Huber, W; Kraupp-Grasl, B; Putz, B; Schulte-Hermann, R | 1 |
| Yu, SZ; Zhou, TL | 1 |
| Davis, EF; Huber, LJ; Kim, Y; McMahon, G; Wogan, GN | 1 |
| Cova, L; Jacquet, C; Lambert, V; Mehrotra, R; Montesano, R; Shirai, T; Tomatis, L; Trépo, C; Turusov, V; Wild, CP | 1 |
| Du, MJ; Hsieh, DP; Lei, DN; Ruebner, BH; Wang, LQ; Wu, BF; Zhu, CR | 1 |
| Morimura, S; Tashiro, F; Ueno, Y | 1 |
| Wang, LQ | 2 |
| Corcos, L; Kiefer, F; Rousset, JP; Weiss, MC; Wiebel, FJ | 1 |
| de Camargo, JL; Locniskar, M; Newberne, PM; Suphiphat, V | 1 |
| Angrand, PO; Kallenbach, S; Rousset, JP; Weiss, MC | 1 |
| Best, SJ; Cameron, RG; Crane, TL; Farber, E; Hayes, MA; Kocal, TE; Quinn, BA; Rushmore, TH | 1 |
| Newberne, PM; Sondergaard, D; Taylor, F | 1 |
| Castelli, D; Krebs, B; Lafaurie, M; Seralini, GE; Stora, C | 1 |
| Chen, ZY; Qin, GZ; Qin, LL; Yan, RQ | 1 |
| Angsubhakorn, S; Bhamarapravati, N; Im-Emgamol, N; Pradermwong, A; Sahaphong, S | 1 |
| Hara, A; Hirono, I; Iwata, H; Mori, H; Mori, Y; Nishikawa, A; Tanaka, T | 1 |
| Yan, RQ | 1 |
| Bednarz, W | 1 |
| Campbell, TC; Root, MM; Schulsinger, DA | 1 |
| Gebhardt, R; Tanaka, T; Williams, GM | 1 |
| Fukushima, S; Imaida, K; Ito, N; King, CM; Lee, MS; Ohshima, M; Shirai, T | 1 |
| Ali, II; Couri, D; Milks, MM; Wilt, SR | 1 |
| Chang, LW; Klaunig, JE; Pereira, MA | 1 |
| Bannasch, P; Benner, U; Enzmann, H; Hacker, HJ | 1 |
| Maeura, Y; Tanaka, T; Williams, GM | 1 |
| Davidson, NE; Egner, PA; Groopman, JD; Kensler, TW; Pikul, A; Roebuck, BD | 1 |
| Driver, HE; Green, JA; Manson, MM | 1 |
| Dolan, PM; Egner, PA; Groopman, JD; Kensler, TW; Roebuck, BD | 1 |
| Campbell, TC; Dunaif, GE | 1 |
| Forrester, LM; Green, JA; Judah, DJ; Mandel, HG; Manson, MM; Neal, GE; Simpson, JL; Wolf, CR | 1 |
| Boix, J; Callaghan, R; Gil, R; Llombart-Bosch, A; Pellin, A | 1 |
| Horikoshi, N; Tanaka, N; Tashiro, F; Ueno, Y | 1 |
| Hayashi, K; Horikoshi, N; Kawamura, H; Makino, R; Morimura, S; Nemoto, K; Ohtsubo, K; Sugimura, T; Tashiro, F; Ueno, Y | 1 |
| Pironcheva, GL; Russev, GH | 1 |
| Akao, M; Kuroda, K; Terao, K | 1 |
| Angsubhakorn, S; Bhamarapravati, N; Sathiropas, P | 1 |
| Campbell, J; Clayson, D; Hayward, S; Hierlihy, S; Iverson, F; Labossiere, E | 1 |
| Cullen, JM; Hsieh, DP; Hsieh, LS; Hyde, DM; Ruebner, BH | 1 |
| Bailey, GS; Hendricks, JD; Nixon, JE; Pawlowski, NE; Shelton, DW | 1 |
| Fennell, TR; Swenberg, JA | 1 |
| Neumann, HG | 1 |
| de Camargo, J; Newberne, PM; Punyarit, P; Suphakarn, V | 1 |
| Kärenlampi, SO | 1 |
| Davis, E; McMahon, G; Wogan, GN | 1 |
| Manson, MM; Neal, GE; Power, C; Sinha, S; Webber, C | 1 |
| Elashoff, RM; Fears, TR; Schneiderman, MA | 1 |
| Bailey, G; Davie, JR; Delcuve, GP; Moirier, R; Nickel, BE | 1 |
| Angsubhakorn, S; Bhamarapravati, N; Sahaphong, S; Sathiropas, P | 1 |
| Arii, M; Esumi, M; Shikata, T; Suzuki, K; Uchida, T | 1 |
| Butler, WH; Pritchard, DJ | 2 |
| el-Mofty, MM; Sakr, SA | 1 |
| Ishikawa, T; Moore, MA; Nakagawa, K | 1 |
| McConnell, EE; Soffritti, M | 1 |
| Maier, P; Schawalder, HP | 1 |
| Corcos, L; Weiss, MC | 1 |
| Lin, C | 1 |
| Zhu, CR | 1 |
| Bansal, SK; Fox, HW; Gurtoo, HL; Koser, PL; Mulhern, AI; Pavelic, ZP; Sharma, SD | 1 |
| Brooks, L; Clark, I; Gallo, MA; McCoy, JR | 1 |
14 review(s) available for aflatoxin b1 and Experimental Hepatoma
| Article | Year |
|---|---|
An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.
Topics: Aflatoxin B1; Animals; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Humans; Liver Neoplasms, Experimental; Mutagens; Mutation; Rats; Risk Assessment; Tamoxifen; Tissue Distribution; Vinyl Chloride | 2014 |
The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.
Topics: Aflatoxin B1; Animals; Benzopyrenes; Caprylates; Chemoprevention; Chlorophyllides; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Environmental Exposure; Fluorocarbons; Indoles; Liver; Liver Neoplasms, Experimental; Oncorhynchus mykiss; Promoter Regions, Genetic; Risk Assessment | 2012 |
Hyperplasia, partial hepatectomy, and the carcinogenicity of aflatoxin B1.
Topics: Aflatoxin B1; Animals; Body Weight; Carcinogens; Hepatectomy; Hyperplasia; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Rats | 2004 |
[Co-inactivation of the p53 and RB genes in human hepato cellular carcinoma].
Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Chromosome Aberrations; Gene Deletion; Genes, p53; Genes, Retinoblastoma; Heterozygote; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mutation; Polymorphism, Restriction Fragment Length; Risk Factors | 1993 |
Molecular dosimetry of aflatoxin exposure: contribution to understanding the multifactorial etiopathogenesis of primary hepatocellular carcinoma with particular reference to hepatitis B virus.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; DNA; DNA Adducts; Epidemiologic Methods; Hepatitis B; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Serum Albumin | 1993 |
Regulation of glutathione S-transferases and aldehyde reductase by chemoprotectors: studies of mechanisms responsible for inducible resistance to aflatoxin B1.
Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Anticarcinogenic Agents; Biotransformation; Carcinogens; Drug Resistance; Ethoxyquin; Glutathione Transferase; Humans; Liver Neoplasms, Experimental; Rats | 1996 |
The molecular mechanism of aflatoxin B1-induced liver cancer: is mitotic recombination involved?
Topics: Aflatoxin B1; Animals; Carcinogens; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mitosis; Recombination, Genetic | 1997 |
Chemopreventive properties of chlorophylls towards aflatoxin B1: a review of the antimutagenicity and anticarcinogenicity data in rainbow trout.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Chlorophyllides; DNA Adducts; Liver Neoplasms, Experimental; Models, Molecular; Oncorhynchus mykiss | 1998 |
Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1.
Topics: Aflatoxin B1; Aldehyde Reductase; Amino Acid Sequence; Animals; Antioxidants; Base Sequence; Biotransformation; Cloning, Molecular; DNA; Drug Resistance; Enzyme Induction; Ethoxyquin; Glutathione Transferase; Inactivation, Metabolic; Liver Neoplasms, Experimental; Molecular Sequence Data; Oxidative Stress; Protein Conformation; Rats | 1998 |
Impacts of chemicals on liver cancer risk.
Topics: Aflatoxin B1; Animals; Carcinogens; DNA, Neoplasm; Genes, p53; Haplorhini; Hepatitis B; Hepatitis C; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Rats; Risk Factors | 2000 |
[Hepatocarcinogenesis with chemicals including mycotoxins].
Topics: Acetamides; Aflatoxin B1; Animals; Azo Compounds; Contraceptives, Oral; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mycotoxins | 2001 |
Carcinogenicity of ochratoxin A in experimental animals.
Topics: Adenofibroma; Adenoma; Adult; Aflatoxin B1; Animals; Balkan Nephropathy; Bulgaria; Carcinogenicity Tests; Carcinoma; Carcinoma, Transitional Cell; Chemical and Drug Induced Liver Injury; Cocarcinogenesis; Comorbidity; Female; Hepatectomy; Humans; Hyperplasia; Incidence; Kidney; Kidney Neoplasms; Liver Diseases; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Middle Aged; Mycotoxins; Ochratoxins; Precancerous Conditions; Rats; Rats, Inbred F344; Romania; Species Specificity; Urologic Neoplasms; Yugoslavia | 1991 |
DNA damage and repair in mouse liver.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Alkylating Agents; Animals; Benzene Derivatives; Carcinogens; DNA; DNA Repair; Liver; Liver Neoplasms, Experimental; Mice; p-Aminoazobenzene; Polycyclic Compounds | 1987 |
Variables influencing DNA-binding in mouse liver.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzene Derivatives; Carcinogens; DNA; DNA Repair; Fluorenes; Liver; Liver Neoplasms, Experimental; Mice; Mutagenicity Tests; Rats; Species Specificity | 1987 |
230 other study(ies) available for aflatoxin b1 and Experimental Hepatoma
| Article | Year |
|---|---|
SIRT1-mediated amelioration of oxidative stress in kidney of alcohol-aflatoxin-B1-induced hepatocellular carcinoma by resveratrol is catalase dependent and GPx independent.
Topics: Aflatoxin B1; Animals; Catalase; Ethanol; Glutathione Peroxidase; Kidney; Liver Neoplasms, Experimental; Male; Oxidative Stress; Rats, Wistar; Resveratrol; Sirtuin 1 | 2020 |
Modulation of antioxidant enzymes, SIRT1 and NF-κB by resveratrol and nicotinamide in alcohol-aflatoxin B1-induced hepatocellular carcinoma.
Topics: Aflatoxin B1; Animals; Antioxidants; Carcinoma, Hepatocellular; Ethanol; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; NF-kappa B; Niacinamide; Rats; Resveratrol; Sirtuin 1 | 2021 |
Protective and therapeutic effects of sildenafil and tadalafil on aflatoxin B1-induced hepatocellular carcinoma.
Topics: Aflatoxin B1; Animals; Antioxidants; Carcinoma, Hepatocellular; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Phosphodiesterase 5 Inhibitors; Poisons; Rats; Sildenafil Citrate; Tadalafil; Vasodilator Agents | 2021 |
RNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated rats.
Topics: Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; E2F1 Transcription Factor; Exons; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glucuronosyltransferase; High-Throughput Nucleotide Sequencing; Liver; Liver Neoplasms, Experimental; Male; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Principal Component Analysis; Rats; RNA, Messenger; Sequence Analysis, RNA; Transcriptome | 2013 |
Transcriptome profiling of malignant transformed rat hepatic stem-like cells by aflatoxin B1.
Topics: Aflatoxin B1; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Neoplastic Stem Cells; Rats; Signal Transduction | 2014 |
Complete protection against aflatoxin B(1)-induced liver cancer with a triterpenoid: DNA adduct dosimetry, molecular signature, and genotoxicity threshold.
Topics: Aflatoxin B1; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Imidazoles; Liver Neoplasms, Experimental; Male; Oleanolic Acid; Oligonucleotide Array Sequence Analysis; Poisons; Precancerous Conditions; Rats; Rats, Inbred F344 | 2014 |
Laboratory to community: chemoprevention is the answer.
Topics: Aflatoxin B1; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; DNA Adducts; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Imidazoles; Liver Neoplasms, Experimental; Male; Oleanolic Acid | 2014 |
Of mice, rats, and men: could Nrf2 activation protect against aflatoxin heptocarcinogenesis in humans?
Topics: Aflatoxin B1; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; DNA Adducts; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Imidazoles; Liver Neoplasms, Experimental; Male; Oleanolic Acid | 2014 |
Activation of oxidative stress and inflammatory factors could account for histopathological progression of aflatoxin-B1 induced hepatocarcinogenesis in rat.
Topics: Aflatoxin B1; Animals; Cytokines; Glutathione S-Transferase pi; Liver; Liver Neoplasms, Experimental; Male; Oxidative Stress; Proliferating Cell Nuclear Antigen; Rats; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Up-Regulation | 2015 |
Purple rice bran extract attenuates the aflatoxin B1-induced initiation stage of hepatocarcinogenesis by alteration of xenobiotic metabolizing enzymes.
Topics: Aflatoxin B1; Animals; Carcinogenesis; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochromes; Glucuronosyltransferase; Glutathione Transferase; Hepatocytes; Liver; Liver Neoplasms, Experimental; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; NADPH-Ferrihemoprotein Reductase; Oryza; Plant Extracts; Poisons; Rats | 2015 |
Molecular characterization of hepatocarcinogenesis using mouse models.
Topics: Aflatoxin B1; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Profiling; Hepatitis B; Hepatitis B Surface Antigens; Humans; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2015 |
Fisetin Modulates Antioxidant Enzymes and Inflammatory Factors to Inhibit Aflatoxin-B1 Induced Hepatocellular Carcinoma in Rats.
Topics: Aflatoxin B1; Animals; Antioxidants; Carcinoma, Hepatocellular; Flavonoids; Flavonols; Interleukin-1alpha; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Oxidative Stress; Oxidoreductases; Rats; Tumor Necrosis Factor-alpha | 2016 |
Sequential dietary exposure to aflatoxin B1 and fumonisin B1 in F344 rats increases liver preneoplastic changes indicative of a synergistic interaction.
Topics: Aflatoxin B1; Animals; Carcinogens, Environmental; Diet; Drug Interactions; Drug Synergism; Fumonisins; Glutathione S-Transferase pi; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Poisons; Precancerous Conditions; Rats; Rats, Inbred F344 | 2016 |
Naturally occurring chlorophyll derivatives inhibit aflatoxin B1-DNA adduct formation in hepatoma cells.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Cell Line, Tumor; Chlorophyll; Chlorophyllides; DNA Adducts; Glutathione Transferase; Liver Neoplasms, Experimental; Mice | 2008 |
Glycine N-methyltransferase affects the metabolism of aflatoxin B1 and blocks its carcinogenic effect.
Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Adducts; Female; Glycine N-Methyltransferase; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Transgenic | 2009 |
Aflatoxin B1 and/or hepatitis B virus induced tumor spectrum in a genetically engineered hepatitis B virus expression and Trp53 haploinsufficient mouse model system for hepatocarcinogenesis.
Topics: Aflatoxin B1; Animals; Disease Models, Animal; Female; Genetic Engineering; Hepatitis B Surface Antigens; Hepatitis B virus; Immunohistochemistry; Kaplan-Meier Estimate; Ki-67 Antigen; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Sex Factors; Survival Analysis; Tumor Suppressor Protein p53 | 2009 |
Hepatocellular carcinoma in GNMT-/- mice.
Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Female; Glycine N-Methyltransferase; Liver Neoplasms, Experimental; Male; Mice; Mice, Transgenic; Publications | 2009 |
[Ginkgo biloba extracts (EGb761) inhibits aflatoxin B1-induced hepatocarcinogenesis in Wistar rats].
Topics: Aflatoxin B1; Animals; Antioxidants; Ginkgo biloba; Glutathione Peroxidase; Liver; Liver Neoplasms, Experimental; Male; Malondialdehyde; Plant Extracts; Plant Leaves; Plants, Medicinal; Precancerous Conditions; Random Allocation; Rats; Rats, Wistar | 2009 |
RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1.
Topics: Aflatoxin B1; Animals; Animals, Newborn; Cell Cycle; Cyclin D1; DNA Damage; E2F1 Transcription Factor; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Mice; Mitosis; Retinoblastoma Protein | 2009 |
Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens.
Topics: Adaptive Immunity; Aflatoxin B1; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Chemokines; Cocarcinogenesis; Female; Helicobacter hepaticus; Helicobacter Infections; Hepatitis B; Immunity, Innate; Interleukin-12 Subunit p40; Intestines; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Sex Factors; Signal Transduction; Th1 Cells | 2010 |
Aflatoxin B1 modulates the insulin-like growth factor-2 dependent signaling axis.
Topics: Aflatoxin B1; Animals; Blotting, Western; Carcinogens; Cell Line, Tumor; Cell Proliferation; DNA Primers; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Insulin-Like Growth Factor II; Liver Neoplasms, Experimental; Neoplasm Metastasis; Phosphorylation; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Signal Transduction | 2010 |
Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents.
Topics: Aflatoxin B1; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cells, Cultured; Cytoprotection; Enzyme Induction; Heme Oxygenase-1; Interferon-gamma; Liver; Liver Neoplasms, Experimental; Macrophages; Male; Mice; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide Synthase Type II; Nitriles; Pentacyclic Triterpenes; Phenanthrenes; Precancerous Conditions; Rats; Stereoisomerism; Stomach; Structure-Activity Relationship | 2011 |
Increased incidence of aflatoxin B1-induced liver tumors in hepatitis virus C transgenic mice.
Topics: Aflatoxin B1; Animals; Fatty Liver; Follow-Up Studies; Hepacivirus; Hepatitis C; Inflammation; Lipid Metabolism; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress | 2012 |
Anticarcinogenic effect of probiotic fermented milk and chlorophyllin on aflatoxin-B₁-induced liver carcinogenesis in rats.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Chlorophyllides; Cultured Milk Products; Glutathione; Lacticaseibacillus casei; Lacticaseibacillus rhamnosus; Liver Neoplasms, Experimental; Male; Probiotics; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2012 |
Hepatic oval cell lines generate hepatocellular carcinoma following transfection with HBx gene and treatment with aflatoxin B1 in vivo.
Topics: Aflatoxin B1; Animals; Cell Line, Tumor; Hepatocytes; Liver; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Rats; Trans-Activators; Transfection; Viral Regulatory and Accessory Proteins | 2011 |
Promotion of hepatocarcinogenesis by perfluoroalkyl acids in rainbow trout.
Topics: Aflatoxin B1; Alkanesulfonic Acids; Animals; Caprylates; Carcinogenicity Tests; Cocarcinogenesis; Decanoic Acids; Endocrine Disruptors; Fluorocarbons; Gene Expression; Gene Expression Profiling; Hydrocarbons, Fluorinated; Liver Neoplasms, Experimental; Methylnitronitrosoguanidine; Oligonucleotide Array Sequence Analysis; Oncorhynchus mykiss; Real-Time Polymerase Chain Reaction | 2012 |
Mechanisms of protection against aflatoxin B(1) genotoxicity in rats treated by organosulfur compounds from garlic.
Topics: Aflatoxin B1; Aldehyde Reductase; Allyl Compounds; Animals; Antimutagenic Agents; Disulfides; Garlic; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Mutagens; Rats; Rats, Wistar; Sulfides | 2002 |
[Different gene expression during hepatocarcinogenesis in tree shrew induced by aflatoxin B1].
Topics: Aflatoxin B1; Animals; Gene Expression Profiling; Liver Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Tupaiidae | 2003 |
[Alteration of p53 gene during tree shrews' hepatocarcinogenesis].
Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; Gene Expression Regulation, Neoplastic; Genetic Variation; Hepatitis B; Hepatitis B virus; Liver Neoplasms, Experimental; Point Mutation; RNA, Neoplasm; Tumor Suppressor Protein p53; Tupaiidae | 2003 |
Promotion of aflatoxin B1-induced hepatocarcinogenesis by dichlorodiphenyl trichloroethane (DDT).
Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; DDT; Liver; Liver Neoplasms, Experimental; Male; Random Allocation; Rats; Rats, Inbred BUF; Rats, Wistar; Survival Analysis | 2002 |
Susceptibility to aflatoxin B1-related primary hepatocellular carcinoma in mice and humans.
Topics: Aflatoxin B1; Amino Acid Sequence; Animals; Carcinoma, Hepatocellular; Case-Control Studies; Cocarcinogenesis; Conserved Sequence; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mice, Transgenic; Middle Aged; Molecular Sequence Data | 2003 |
Long-term intake of a low-casein diet is associated with higher relative NK cell cytotoxic activity in F344 rats.
Topics: Aflatoxin B1; Animals; Body Weight; Caseins; Cytotoxicity, Immunologic; Dietary Proteins; Eating; Killer Cells, Natural; Liver Neoplasms, Experimental; Lymphocyte Activation; Male; Random Allocation; Rats; Rats, Inbred F344; Time Factors | 1994 |
[Differentially expressed genes in hepatocellular carcinoma of tree shrew induced by different factors].
Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Female; Gene Expression Profiling; Hepatitis B; Humans; Liver Neoplasms, Experimental; Male; Tupaiidae | 2003 |
Comparison of the chemopreventive efficacies of garlic powders with different alliin contents against aflatoxin B1 carcinogenicity in rats.
Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Chemoprevention; Cysteine; Cytochrome P-450 CYP1A1; Diet; Garlic; Glucuronosyltransferase; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Powders; Precancerous Conditions; Rats; Rats, Wistar | 2004 |
The effect of modulation of glutathione levels on markers for aflatoxin B1-induced cell damage.
Topics: Acetaminophen; Aflatoxin B1; Animals; Biomarkers; Glutathione; Glutathione Transferase; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Mice; Rats | 2005 |
Dynamic expression of apoptosis-related genes during development of laboratory hepatocellular carcinoma and its relation to apoptosis.
Topics: Aflatoxin B1; Animals; Apoptosis; bcl-2-Associated X Protein; Gene Expression; Genes, bcl-2; Genes, p53; Liver Neoplasms, Experimental; Microtubule-Associated Proteins; Proto-Oncogene Proteins c-bcl-2; Tupaiidae | 2005 |
Benchmark analysis: shopping with proper confidence.
Topics: Aflatoxin B1; Animals; Benchmarking; Carcinogens; Confidence Intervals; Environmental Exposure; Environmental Pollutants; Humans; Liver Neoplasms, Experimental; Models, Statistical; Risk Assessment | 2005 |
Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; DNA Adducts; Gene Expression Regulation, Neoplastic; Imidazoles; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; NF-E2-Related Factor 2; Oleanolic Acid; Rats; Rats, Inbred F344 | 2006 |
Using salmonid microarrays to understand the dietary modulation of carcinogenesis in rainbow trout.
Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Indoles; Liver Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Oncorhynchus mykiss; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Vitellogenins | 2006 |
Inhibition of carcinogen-induced DNA damage in rat liver and colon by garlic powders with varying alliin content.
Topics: 1,2-Dimethylhydrazine; Aflatoxin B1; Animals; Antineoplastic Agents; Chemoprevention; Colon; Colonic Neoplasms; Comet Assay; Cysteine; Dimethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Fertilizers; Garlic; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Wistar; Specific Pathogen-Free Organisms | 2006 |
Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Blotting, Western; Carcinogens; Coffee; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Genes, Reporter; Glutathione; Glutathione Transferase; Hepatocytes; Humans; Liver Neoplasms, Experimental; Luciferases; Male; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Regulatory Elements, Transcriptional; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
[Dynamic expression of survivin during hepatocarcinogenesis in rats].
Topics: Aflatoxin B1; Animals; Apoptosis Regulatory Proteins; Gene Expression Regulation, Neoplastic; Liver; Liver Neoplasms, Experimental; Male; Microtubule-Associated Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Survivin | 2007 |
Proteome analysis of aflatoxin B1-induced hepatocarcinogenesis in tree shrew (Tupaia belangeri chinensis) and functional identification of candidate protein peroxiredoxin II.
Topics: Adult; Aflatoxin B1; Aged; Animals; Carcinoma, Hepatocellular; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mass Spectrometry; Middle Aged; Peroxiredoxins; Reverse Transcriptase Polymerase Chain Reaction; Tupaia | 2008 |
Urinary catabolites of ribonucleic acid as cancer markers: a preliminary report of their use in patients with lung cancer.
Topics: Aflatoxin B1; Aflatoxins; Animals; Dimethylnitrosamine; Female; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Neoplasm Transplantation; Nucleosides; Osteosarcoma; Rats; Rats, Inbred ACI; Rats, Inbred Strains; RNA, Neoplasm; Wilms Tumor | 1984 |
The particular traits of carcinogenesis induced in Wistar rats by aflatoxin B1. III. Porphyrins and the activity of gamma-glutamyltranspeptidase in primary hepatomas and in their tissue of origin.
Topics: Aflatoxin B1; Aflatoxins; Animals; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Porphyrins; Rats; Rats, Inbred Strains; Sex Factors | 1981 |
Inhibition of aflatoxin-initiated preneoplastic liver lesions by low dietary protein.
Topics: Aflatoxin B1; Aflatoxins; Animals; Caseins; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats | 1982 |
The particular traits of carcinogenesis induced in Wistar rats by aflatoxin B1. IV. Porphyrins and the activity of gamma-glutamyltranspeptidase in Wistar rats bearing transplantable hepatoma.
Topics: Aflatoxin B1; Aflatoxins; Animals; Castration; Female; gamma-Glutamyltransferase; Kidney; Liver; Liver Neoplasms, Experimental; Male; Neoplasm Transplantation; Porphyrins; Rats; Rats, Inbred Strains; Sex Factors | 1982 |
Biphasic early changes in rat liver gamma-glutamyl transpeptidase in response to aflatoxin B1.
Topics: Acyltransferases; Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Transglutaminases | 1983 |
Effect of hexachlorobenzene on male and female rat hepatic gamma-glutamyl transpeptidase levels.
Topics: Aflatoxin B1; Aflatoxins; Animals; Chlorobenzenes; Female; gamma-Glutamyltransferase; Hexachlorobenzene; Histocytochemistry; Liver; Liver Neoplasms, Experimental; Male; Porphyrins; Precancerous Conditions; Rats; Rats, Inbred Strains; Sex Factors; Time Factors | 1984 |
Monoclonal antibody against tumour-derived cell line shows heterogeneity of altered hepatocytes during AFB1-induced carcinogenesis.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Line; gamma-Glutamyltransferase; Histocytochemistry; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344 | 1984 |
Inhibition of mitochondrial protein synthesis during early stages of aflatoxin B1-induced hepatocarcinogenesis.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Nucleus; DNA; Liver Neoplasms, Experimental; Male; Mitochondria, Liver; Precancerous Conditions; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA; Transcription, Genetic | 1982 |
Cholangiocellular carcinomas induced in Syrian golden hamsters administered aflatoxin B1 in large doses.
Topics: Adenoma, Bile Duct; Aflatoxin B1; Aflatoxins; Animals; Cricetinae; Dose-Response Relationship, Drug; Liver Neoplasms, Experimental; Male; Mesocricetus; Rats; Rats, Inbred F344; Time Factors | 1982 |
Geno- and cytotoxicity of nitrosamines, aflatoxin B1, and benzo[a]-pyrene in continuous cultures of rat hepatoma cells.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Cell Survival; Clone Cells; Dexamethasone; Diethylnitrosamine; Dimethylnitrosamine; Ethylnitrosourea; Kinetics; Liver Neoplasms, Experimental; Methylnitronitrosoguanidine; Mutation; Nitrosamines; Rats | 1982 |
Comparison of urinary modified nucleosides and bases in rats with hepatomas and nephroblastomas.
Topics: Aflatoxin B1; Aflatoxins; Animals; Deoxyribonucleosides; Dimethylnitrosamine; Kidney Neoplasms; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Nucleosides; Purines; Pyrimidines; Rats; Rats, Inbred Strains; Ribonucleosides; Wilms Tumor | 1983 |
Aflatoxin B1: correlations of patterns of metabolism and DNA modification with biological effects.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; DNA; Kinetics; Liver; Liver Neoplasms, Experimental; Rats | 1983 |
Interactions of aflatoxin B1 and alkylating agents with DNA: structural and functional studies.
Topics: Aflatoxin B1; Aflatoxins; Alkylating Agents; Animals; Carcinogens; Chemical Phenomena; Chemistry; DNA; Kinetics; Liver; Liver Neoplasms, Experimental; Nucleic Acid Conformation; Plasmids; Rats; Rats, Inbred F344 | 1983 |
Anticarcinogenic effect of long-term oral administration of red ginseng on newborn mice exposed to various chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Aflatoxin B1; Aflatoxins; Animals; Animals, Newborn; Carcinogens; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Neoplasms, Experimental; Panax; Plants, Medicinal; Time Factors; Urethane | 1983 |
Metabolism of tRNA in rats with aflatoxin B1-induced hepatomas.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Liver; Liver Neoplasms, Experimental; Male; Nucleosides; Rats; Rats, Inbred Strains; RNA, Transfer | 1983 |
The development of hepatocellular tumours following aflatoxin B1 exposure of the partially hepatectomised mouse.
Topics: Adenoma; Aflatoxin B1; Aflatoxins; Animals; Body Weight; Carcinogens; Hepatectomy; Liver Neoplasms; Liver Neoplasms, Experimental; Liver Regeneration; Male; Mice; Mice, Inbred Strains; Organ Size | 1984 |
Inhibition of aflatoxin B1 carcinogenesis in rainbow trout by flavone and indole compounds.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Indoles; Liver Neoplasms, Experimental; Microsomes, Liver; Mixed Function Oxygenases; Trout | 1984 |
Microinjection of carcinogens into rainbow trout embryos: an in vivo carcinogenesis assay.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Anthracenes; Carcinogens; Drug Evaluation, Preclinical; Embryo, Nonmammalian; Female; Liver; Liver Neoplasms, Experimental; Salmonidae; Trout | 1984 |
Metabolic activation of procarcinogens to genotoxic products in cultured rat liver cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Biotransformation; Carcinogens; Cell Survival; Cyclophosphamide; Liver; Liver Neoplasms, Experimental; Rats; Sister Chromatid Exchange | 1984 |
Comparative hepatocarcinogenicity of aflatoxins B1 and M1 in the rat.
Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Liver Neoplasms, Experimental; Male; Rats | 1984 |
Effects of sequential exposure to aflatoxin B1 and diethylnitrosamine on vascular and stomach tissue and additional target organs in rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Diethylnitrosamine; Hemangiosarcoma; Liver Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Stomach Neoplasms; Time Factors | 1980 |
Regression of aflatoxin B1-induced hepatocellular carcinomas by reduced glutathione.
Topics: Aflatoxin B1; Aflatoxins; Animals; Female; Glutathione; Liver Neoplasms, Experimental; Rats | 1981 |
Carcinogen-induced drug resistance in rat hepatocytes.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Cell Cycle; Cell Survival; Cells, Cultured; Cycloheximide; Doxorubicin; Drug Resistance; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methotrexate; Rats | 1981 |
Null effect of dietary Aroclor 1254 on hepatocellular carcinoma incidence in rainbow trout (Salmo gairdneri) exposed to aflatoxin B1 as embryos.
Topics: Aflatoxin B1; Aflatoxins; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Diet; Drug Interactions; Lipid Metabolism; Liver Neoplasms, Experimental; Polychlorinated Biphenyls; Salmonidae; Trout | 1980 |
Carcinogenicity of aflatoxicol in Fischer 344 rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Carcinogens; Diet; Inactivation, Metabolic; Isomerism; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344 | 1981 |
Cytophotometric and cytogenetic characteristics of primary hepatomas induced in Wistar rats by aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Chromosome Aberrations; DNA, Neoplasm; Liver Neoplasms, Experimental; Rats | 1981 |
Enhancing effects of dimethylnitrosamine on aflatoxin B hepatocarcinogenesis in rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Dimethylnitrosamine; Drug Synergism; Food, Formulated; Liver; Liver Neoplasms, Experimental; Male; Rats | 1981 |
Enhanced susceptibility to aflatoxin B1 toxicity in weanling mice pretreated with carbon tetrachloride.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carbon Tetrachloride Poisoning; Drug Synergism; Lethal Dose 50; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred CBA; Necrosis; Weaning | 1981 |
Dose responses of five hepatocarcinogens for the initiation of rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Hepatectomy; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; p-Dimethylaminoazobenzene; Rats | 1981 |
Liver DNA bound in vivo with aflatoxin B1 as a measure of hepatocarcinoma initiation in rainbow trout.
Topics: Aflatoxin B1; Aflatoxins; Animals; Dietary Proteins; DNA; Fishes; Liver; Liver Neoplasms, Experimental; Precancerous Conditions | 1982 |
Rat hepatoma cells show extreme sensitivity to aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Cell Line; DNA, Neoplasm; Liver Neoplasms, Experimental; Mutagens; Rats | 1982 |
Mechanisms of chlorophyllin anticarcinogenesis against aflatoxin B1: complex formation with the carcinogen.
Topics: Aflatoxin B1; Animals; Antimutagenic Agents; Chemical Phenomena; Chemistry, Physical; Chlorophyllides; Chromatography, High Pressure Liquid; DNA; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver Neoplasms, Experimental; Microsomes, Liver; Models, Molecular; Spectrometry, Fluorescence; Trout | 1995 |
Temperature-modulated incidence of aflatoxin B1-initiated liver cancer in rainbow trout.
Topics: Aflatoxin B1; Animals; Cholesterol; Fatty Acids; Liver; Liver Neoplasms, Experimental; Microsomes, Liver; Oncorhynchus mykiss; Phosphatidylcholines; Phospholipids; Temperature | 1995 |
Synergistic hepatocarcinogenic effect of hepadnaviral infection and dietary aflatoxin B1 in woodchucks.
Topics: Aflatoxin B1; Age Factors; Animals; Animals, Newborn; Base Sequence; Biopsy; Carrier State; Cocarcinogenesis; Dimethyl Sulfoxide; DNA, Viral; Female; Hepadnaviridae Infections; Hepatitis Antibodies; Hepatitis, Viral, Animal; Humans; Liver; Liver Neoplasms, Experimental; Male; Marmota; Microscopy, Electron; Molecular Sequence Data | 1995 |
Intermittent dosing with oltipraz: relationship between chemoprevention of aflatoxin-induced tumorigenesis and induction of glutathione S-transferases.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Enzyme Induction; Glutathione Transferase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1995 |
Dietary chlorophyllin is a potent inhibitor of aflatoxin B1 hepatocarcinogenesis in rainbow trout.
Topics: Aflatoxin B1; Animals; Antimutagenic Agents; Chlorophyllides; Diet; DNA; Dose-Response Relationship, Drug; Liver Neoplasms, Experimental; Oncorhynchus mykiss | 1995 |
Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice.
Topics: Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hepatitis B virus; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Mixed Function Oxygenases; Viral Envelope Proteins | 1994 |
Piperine, a major ingredient of black and long peppers, protects against AFB1-induced cytotoxicity and micronuclei formation in H4IIEC3 rat hepatoma cells.
Topics: Aflatoxin B1; Alkaloids; Animals; Benzodioxoles; Cell Death; Liver Neoplasms, Experimental; Micronucleus Tests; Piperidines; Polyunsaturated Alkamides; Rats; Tumor Cells, Cultured | 1994 |
Anticarcinogenic activity of indole-3-carbinol acid products: ultrasensitive bioassay by trout embryo microinjection.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; DNA; Drug Screening Assays, Antitumor; Embryo, Nonmammalian; Indoles; Liver Neoplasms, Experimental; Microinjections; Oncorhynchus mykiss | 1994 |
Association between responsiveness to phenobarbital induction of CYP2B1/2 and 3A1 in rat hepatic hyperplastic nodules and their zonal origin.
Topics: Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344 | 1993 |
Absence of p53 mutation at codon 249 in duck hepatocellular carcinomas from the high incidence area of Qidong (China).
Topics: Aflatoxin B1; Animals; Base Sequence; China; Codon; DNA; Ducks; Genes, p53; Hepatitis B Virus, Duck; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutation | 1994 |
Effect of ammoniation of aflatoxin B1-contaminated cottonseed feedstock on the aflatoxin M1 content of cows' milk and hepatocarcinogenicity in the trout bioassay.
Topics: Aflatoxin B1; Aflatoxin M1; Ammonia; Animal Feed; Animals; Cattle; Cottonseed Oil; Female; Food Contamination; Liver Neoplasms, Experimental; Milk; Oncorhynchus mykiss | 1994 |
Effect of varying the onset of exposure to DDT on its modulation of AFB1-induced hepatocarcinogenesis in the rat.
Topics: Aflatoxin B1; Animals; Cocarcinogenesis; DDT; Dimethyl Sulfoxide; Drug Administration Schedule; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Rats; Rats, Wistar | 1993 |
Sex differences at the initiation stage of rat liver carcinogenesis--influence of growth hormone.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Female; Growth Hormone; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Rats; RNA, Messenger; Sex Characteristics; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1993 |
Glutathione S-transferase isoenzyme patterns in different subtypes of enzyme-altered rat liver foci treated with the peroxisome proliferator nafenopin or with phenobarbital.
Topics: Adenoma; Aflatoxin B1; Animals; Carcinogens; Female; Glutathione Transferase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Macromolecular Substances; Male; Microbodies; Nafenopin; Phenobarbital; Rats; Rats, Wistar | 1993 |
Evaluation of the post-initiation effects of oltipraz on aflatoxin B1-induced preneoplastic foci in a rat model of hepatic tumorigenesis.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Body Weight; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes; Time Factors | 1993 |
The impact of vitamins A,C,E, and selenium compound on prevention of liver cancer in rats.
Topics: Aflatoxin B1; Aminopyrine N-Demethylase; Animals; Ascorbic Acid; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Disease Models, Animal; Drug Evaluation, Preclinical; Liver Neoplasms, Experimental; Male; Rats; Rats, Wistar; Selenium; Vitamin A; Vitamin E | 1993 |
Molecular epidemiology of aflatoxin exposures: validation of aflatoxin-N7-guanine levels in urine as a biomarker in experimental rat models and humans.
Topics: Adolescent; Adult; Aflatoxin B1; Aflatoxins; Animals; Biomarkers; China; DNA; DNA Adducts; DNA Damage; Female; Gambia; Guanine; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Rats; Rats, Inbred F344 | 1993 |
Transient intervention with oltipraz protects against aflatoxin-induced hepatic tumorigenesis.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; DNA; DNA Adducts; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1993 |
Aflatoxin B1-induced rat hepatic hyperplastic nodules do not exhibit a site-specific mutation within the p53 gene.
Topics: Aflatoxin B1; Animals; Base Sequence; Carcinoma, Hepatocellular; Codon; Disease Models, Animal; Genes, p53; Humans; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Molecular Sequence Data; Mutation; Rats; Rats, Inbred F344 | 1993 |
Activation of the c-Ki-ras oncogene in aflatoxin B1-induced hepatocellular carcinoma and adenoma in the rat: detection by denaturing gradient gel electrophoresis.
Topics: Adenoma; Aflatoxin B1; Animals; Base Sequence; Electrophoresis, Agar Gel; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); Rats | 1993 |
A novel aldehyde reductase with activity towards a metabolite of aflatoxin B1 is expressed in rat liver during carcinogenesis and following the administration of an anti-oxidant.
Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Ethoxyquin; Liver; Liver Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred F344; Substrate Specificity | 1993 |
Modulation of c-myc gene expression in rat livers by aflatoxin B1 exposure and age.
Topics: Aflatoxin B1; Aging; Animals; DNA, Neoplasm; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, myc; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Rats; Rats, Inbred F344; RNA, Messenger | 1993 |
Dehydroepiandrosterone is a complete hepatocarcinogen and potent tumor promoter in the absence of peroxisome proliferation in rainbow trout.
Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; Dehydroepiandrosterone; Genes, ras; Liver Neoplasms, Experimental; Microbodies; Mutation; Oncorhynchus mykiss | 1995 |
Human hepatitis B virus and hepatocellular carcinoma. II. Experimental induction of hepatocellular carcinoma in tree shrews exposed to hepatitis B virus and aflatoxin B1.
Topics: Aflatoxin B1; Animals; Carcinogens; DNA, Viral; gamma-Glutamyltransferase; Hepatitis B; Humans; Liver; Liver Neoplasms, Experimental; Precancerous Conditions; Tupaia | 1996 |
Inhibition of the hepatocarcinogenicity of aflatoxin B1 in rats by low levels of the phenolic antioxidants butylated hydroxyanisole and butylated hydroxytoluene.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinogens; Dose-Response Relationship, Drug; Food Contamination; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Rats; Rats, Inbred F344 | 1996 |
Inhibition of aflatoxin Ml excretion in rat urine during dietary intervention with oltipraz.
Topics: Aflatoxin B1; Aflatoxin M1; Animals; Anticarcinogenic Agents; Cytochrome P-450 Enzyme System; Diet; Dose-Response Relationship, Drug; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1996 |
Protection against aflatoxin B1-induced hepatic toxicity as short-term screen of cancer chemopreventive dithiolethiones.
Topics: Aflatoxin B1; Animals; Chemoprevention; Liver; Liver Diseases; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Structure-Activity Relationship | 1996 |
Comparison of the enhancing effects of dehydroepiandrosterone with the structural analog 16 alpha-fluoro-5-androsten-17-one on aflatoxin B1 hepatocarcinogenesis in rainbow trout.
Topics: Aflatoxin B1; Androstenes; Animals; Anticarcinogenic Agents; Carcinogens; Dehydroepiandrosterone; Drug Synergism; Liver Neoplasms, Experimental; Oncorhynchus mykiss | 1996 |
Effect of cell proliferation on initiation of aflatoxin B1-induced enzyme altered hepatic foci in rats and hamsters.
Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Carcinogens; Cell Division; Cricetinae; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Glutathione Transferase; Hepatectomy; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Rats; Rats, Inbred F344; Species Specificity | 1996 |
Inhibition of aflatoxin B1-induced initiation of hepatocarcinogenesis in the rat by green tea.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; DNA Adducts; DNA, Neoplasm; Enzyme Induction; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Tea | 1997 |
Minisatellite rearrangements are increased in liver tumours induced by transplacental aflatoxin B1 treatment of hepatitis B virus transgenic mice, but not in spontaneously arising tumours.
Topics: Aflatoxin B1; Animals; DNA, Satellite; Female; Gene Rearrangement; Hepatitis B virus; Humans; Liver Neoplasms, Experimental; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Mice, Transgenic; Placenta; Pregnancy | 1997 |
Ascorbic acid protects guinea pigs from acute aflatoxin toxicity.
Topics: Administration, Oral; Aflatoxin B1; Alanine Transaminase; Animals; Ascorbic Acid; Aspartate Aminotransferases; Carcinogens; Cytochrome P-450 Enzyme System; Drug Interactions; Glutathione; Glutathione Transferase; Guinea Pigs; Kidney; Lethal Dose 50; Liver; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Spleen; Survival Rate | 1997 |
Protective effect of food additives on aflatoxin-induced mutagenicity and hepatocarcinogenicity.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Carcinogens; Food Additives; Liver Neoplasms, Experimental; Male; Mutagens; Rats; Rats, Wistar | 1997 |
A case of self-experimentation.
Topics: Aflatoxin B1; Aflatoxin M1; Animals; Autoexperimentation; Biomarkers, Tumor; Ethics Committees, Research; Ethics, Medical; Human Experimentation; Humans; Liver Neoplasms, Experimental; Patient Selection; Research Subjects; Risk Assessment | 1997 |
Predictive value of molecular dosimetry: individual versus group effects of oltipraz on aflatoxin-albumin adducts and risk of liver cancer.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Cell Transformation, Neoplastic; DNA Adducts; Dose-Response Relationship, Drug; Drug Administration Schedule; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1997 |
Protection conferred by selenium deficiency against aflatoxin B1 in the rat is associated with the hepatic expression of an aldo-keto reductase and a glutathione S-transferase subunit that metabolize the mycotoxin.
Topics: Acetylcysteine; Aflatoxin B1; Aldehyde Reductase; Animals; Antioxidants; Cytosol; DNA Adducts; DNA Damage; Glutathione Transferase; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; Oxidative Stress; Rats; Rats, Inbred F344; RNA, Messenger; Selenium | 1997 |
Modulation of aflatoxin-B1 hepatocarcinogenesis in trout by dehydroepiandrosterone: initiation/post-initiation and latency effects.
Topics: Aflatoxin B1; Animals; Carcinogens; CDC2 Protein Kinase; Cell Cycle; Dehydroepiandrosterone; Diet; Drug Administration Schedule; Drug Synergism; Liver; Liver Neoplasms, Experimental; Time Factors; Trout; Tumor Suppressor Protein p53 | 1998 |
Dietary carotenoids inhibit aflatoxin B1-induced liver preneoplastic foci and DNA damage in the rat: role of the modulation of aflatoxin B1 metabolism.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Carotenoids; Diet; DNA Damage; Liver Neoplasms, Experimental; Male; Methylcholanthrene; Microsomes, Liver; Precancerous Conditions; Rats; Rats, Wistar; Serum Albumin; Vitamin A | 1998 |
The mouse equivalent of the human p53ser249 mutation p53ser246 enhances aflatoxin hepatocarcinogenesis in hepatitis B surface antigen transgenic and p53 heterozygous null mice.
Topics: Aflatoxin B1; Animals; Carcinogens; Female; Genes, p53; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Tumor Suppressor Protein p53 | 1998 |
p53 point mutation enhanced by hepatic regeneration in aflatoxin B1-induced rat liver tumors and preneoplastic lesions.
Topics: Aflatoxin B1; Animals; Codon; Genes, p53; Liver Neoplasms, Experimental; Liver Regeneration; Male; Point Mutation; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1998 |
Suppression of arachidonic acid cascade-mediated apoptosis in aflatoxin B1-induced rat hepatoma cells by glucocorticoids.
Topics: Aflatoxin B1; Animals; Apoptosis; Arachidonic Acid; Carcinogens; Estradiol; Estrogen Antagonists; Gene Expression; Glucocorticoids; Lipoxygenase; Liver Neoplasms, Experimental; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Signal Transduction; Tamoxifen; Transforming Growth Factor beta | 1998 |
Identification of dithiolethiones with better chemopreventive properties than oltipraz.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Enzyme Induction; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1998 |
Chemoprevention of aflatoxin B1-induced carcinogenesis by indole-3-carbinol in rat liver--predicting the outcome using early biomarkers.
Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Cytochrome P-450 Enzyme System; gamma-Glutamyltransferase; Glutathione Transferase; Indoles; Keratins; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1998 |
Enhancement of aflatoxin B1-induced enzyme altered hepatic foci in rats by treatment with carbon tetrachloride.
Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Drug Synergism; Fibrosis; gamma-Glutamyltransferase; Glutathione Transferase; Immunohistochemistry; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Rats | 1998 |
Potency of dietary indole-3-carbinol as a promoter of aflatoxin B1-initiated hepatocarcinogenesis: results from a 9000 animal tumor study.
Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Indoles; Liver Neoplasms, Experimental; Oncorhynchus mykiss | 1999 |
Anticancer potency of the milk extract of Semecarpus anacardium Linn. nuts against aflatoxin B1 mediated hepatocellular carcinoma bearing Wistar rats with reference to tumour marker enzymes.
Topics: Aflatoxin B1; Alanine Transaminase; Alkaline Phosphatase; Animals; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; gamma-Glutamyltransferase; L-Lactate Dehydrogenase; Liver Neoplasms, Experimental; Male; Nuts; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar | 1999 |
The expression of insulin-like growth factor II, hepatitis B virus X antigen and p21 in experimental hepatocarcinogenesis in tree shrews.
Topics: Aflatoxin B1; Animals; Cocarcinogenesis; Hepatitis B; Hepatitis B Antigens; Immunohistochemistry; In Vitro Techniques; Insulin-Like Growth Factor II; Liver Neoplasms, Experimental; Oncogene Protein p21(ras); Trans-Activators; Tupaiidae; Viral Regulatory and Accessory Proteins | 1999 |
Synergistic effect of hepatitis B virus and aflatoxin B1 in hepatocarcinogenesis in tree shrews.
Topics: Aflatoxin B1; Animals; Cocarcinogenesis; Female; Hepatitis B; Liver; Liver Neoplasms, Experimental; Male; Tupaiidae | 1999 |
Temporal patterns of DNA adduct formation and glutathione S-transferase activity in the testes of rats fed aflatoxin B1: a comparison with patterns in the liver.
Topics: Aflatoxin B1; Animals; Body Weight; Chromatography, High Pressure Liquid; Diet; DNA Adducts; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Mutagens; Organ Size; Rats; Rats, Inbred F344; Testis | 1999 |
Chlorophyllin chemoprevention in trout initiated by aflatoxin B(1) bath treatment: An evaluation of reduced bioavailability vs. target organ protective mechanisms.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antimutagenic Agents; Biological Availability; Carcinogens; Chelating Agents; Chlorophyllides; DNA Adducts; Fishes; Liver; Liver Neoplasms, Experimental; Time Factors; Trout | 1999 |
2-(Allylthio)pyrazine inhibition of aflatoxin B1-induced hepatocarcinogenesis in rats.
Topics: Aflatoxin B1; Animals; Carcinogenicity Tests; DNA Adducts; DNA, Neoplasm; Enzyme Inhibitors; Glutathione Transferase; Hepatectomy; Immunoenzyme Techniques; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Pyrazines; Rats; Rats, Sprague-Dawley; RNA | 1999 |
Semecarpus anacardium L. nut extract administration induces the in vivo antioxidant defence system in aflatoxin B1 mediated hepatocellular carcinoma.
Topics: Aflatoxin B1; Animals; Antioxidants; Ascorbic Acid; Carcinogens; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; India; Liver Neoplasms, Experimental; Male; Nuts; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Uric Acid; Vitamin E | 1999 |
The promotion effect of anorectic drugs on aflatoxin B(1)-induced hepatic preneoplastic foci.
Topics: Adipose Tissue, Brown; Aflatoxin B1; Amphetamine; Animals; Appetite Depressants; Biomarkers; Body Temperature Regulation; Carcinogens; Chemical and Drug Induced Liver Injury; Cocarcinogenesis; Dopamine; Drug Synergism; Eating; Energy Metabolism; Fenfluramine; Fluoxetine; gamma-Glutamyltransferase; Growth Disorders; Hypothyroidism; Liver Diseases; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Serotonin; Weight Loss | 1999 |
Chemical hepatocarcinogenesis in transgenic mice overexpressing mature TGF beta-1 in liver.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinogens; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Transforming Growth Factor beta | 1999 |
Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver.
Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Coumarins; Enzyme Induction; Female; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Quinone Reductases; Rabbits; Rats; Rats, Inbred F344; Sex Factors | 2000 |
Interactive effects of methyl-deficiency and dietary restriction on liver cell proliferation and telomerase activity in Fischer 344 rats pretreated with aflatoxin B(1).
Topics: Aflatoxin B1; Animals; Carcinogens; Cell Division; Choline Deficiency; Food Deprivation; Liver; Liver Neoplasms, Experimental; Male; Nutritional Status; Precancerous Conditions; Rats; Rats, Inbred F344; Telomerase | 2000 |
Potency of Semecarpus anacardium Linn. nut milk extract against aflatoxin B(1)-induced hepatocarcinogenesis: reflection on microsomal biotransformation enzymes.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Inactivation, Metabolic; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Seeds | 2000 |
Regulation of rat glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) subunits by chemopreventive agents and in aflatoxin B(1)-induced preneoplasia.
Topics: 4-Butyrolactone; Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catalytic Domain; Coumarins; Diet; Ellagic Acid; Enzyme Induction; Ethoxyquin; Glutamate-Cysteine Ligase; Glutathione; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Wistar | 2000 |
Suppressive effect of penta-acetyl geniposide on the development of gamma-glutamyl transpeptidase foci-induced by aflatoxin B(1) in rats.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Drugs, Chinese Herbal; gamma-Glutamyltransferase; Glucosides; Iridoid Glucosides; Iridoids; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrans; Rats; Rats, Wistar | 2000 |
Hepadnaviral hepatocarcinogenesis: in situ visualization of viral antigens, cytoplasmic compartmentation, enzymic patterns, and cellular proliferation in preneoplastic hepatocellular lineages in woodchucks.
Topics: Aflatoxin B1; Animals; Animals, Newborn; Antigens, Viral; Apoptosis; Cell Division; Disease Models, Animal; Hepatitis B Virus, Woodchuck; Humans; Liver; Liver Neoplasms, Experimental; Marmota; Precancerous Conditions; Risk Factors | 2000 |
Mechanisms involved in the chemoprevention of flavonoids.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Cytosol; Diet; DNA; Flavanones; Flavones; Flavonoids; Glutathione; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Quercetin; Rats; Rats, Wistar | 2000 |
Involvement of mu class glutathione S-transferase subunit M2 (rGST M2) levels in the initiation and promotion of hepatocellular carcinogenesis in old rats.
Topics: Aflatoxin B1; Aging; Animals; Carcinogens; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Protein Subunits; Rats; Rats, Wistar | 2001 |
Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout.
Topics: Aflatoxin B1; Air Sacs; Animals; Carboxylic Acids; Carcinogenicity Tests; Carcinogens; Diet; Drug Synergism; Fumonisins; Kidney Neoplasms; Liver; Liver Neoplasms, Experimental; Methylnitronitrosoguanidine; Mycotoxins; Oncorhynchus mykiss; Sphingosine; Stomach Neoplasms | 2001 |
Protection of salvia miltiorrhiza against aflatoxin-B1-induced hepatocarcinogenesis in Fischer 344 rats dual mechanisms involved.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aflatoxin B1; Alanine Transaminase; Animals; Anticarcinogenic Agents; Antioxidants; Aspartate Aminotransferases; Body Weight; Carcinogens; Deoxyguanosine; DNA; DNA Adducts; DNA Primers; Drugs, Chinese Herbal; Fluorescent Antibody Technique, Indirect; Free Radical Scavengers; Glutathione Transferase; Image Processing, Computer-Assisted; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Medicine, Chinese Traditional; Plant Extracts; Rats; Rats, Inbred F344; RNA, Messenger; Salvia miltiorrhiza | 2001 |
Chemoprevention of aflatoxin B1-initiated and carbon tetrachloride-promoted hepatocarcinogenesis in the rat by green tea.
Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Cell Division; Cell Transformation, Neoplastic; Fibrosis; gamma-Glutamyltransferase; Glutathione Transferase; Immunohistochemistry; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Tea | 2000 |
[The relationship between cyanotoxin (microcystin, MC) in pond-ditch water and primary liver cancer in China].
Topics: Aflatoxin B1; Animals; Animals, Genetically Modified; Carcinoma, Hepatocellular; Child; China; Fresh Water; Glutathione Transferase; Hepatectomy; Humans; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Microcystins; Peptides, Cyclic; Rats; Rats, Inbred F344; Trans-Activators; Viral Regulatory and Accessory Proteins | 2001 |
[Protection against synergistic hepatocarcinogenesis of hepatitis B virus expression and aflatoxin B1 by antioxidant 2(3)-tert-4 -hydroxyanisole (BHA) in HBV large envelope transgenic mice].
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Biotransformation; Butylated Hydroxyanisole; Carcinogens; DNA, Viral; Free Radicals; Hepatitis B; Liver Neoplasms, Experimental; Male; Mice; Mice, Transgenic; Oxygen | 1999 |
Low frequency of p53 gene mutation in tumors induced by aflatoxin B1 in nonhuman primates.
Topics: Adenoma, Bile Duct; Aflatoxin B1; Animals; Base Sequence; Bile Duct Neoplasms; Bone Neoplasms; Carcinoma; DNA, Neoplasm; Exons; Genes, p53; Hemangioendothelioma; Introns; Liver Neoplasms; Liver Neoplasms, Experimental; Macaca fascicularis; Macaca mulatta; Molecular Sequence Data; Mutagenesis; Neoplasms, Experimental; Oligodeoxyribonucleotides; Osteosarcoma; Polymerase Chain Reaction | 1992 |
Isolation of a metastasizing cancer cell line from an aflatoxin B1-induced rat liver tumor.
Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Liver Neoplasms, Experimental; Male; Neoplasm Metastasis; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 1992 |
Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes | 1992 |
Influence of different levels of dietary casein on initiation of male rat liver carcinogenesis with a single dose of aflatoxin B1.
Topics: Aflatoxin B1; Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Caseins; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dietary Proteins; gamma-Glutamyltransferase; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Proto-Oncogenes; Rats; Rats, Inbred Strains; Steroid 16-alpha-Hydroxylase | 1992 |
Effect of phenoclor DP6 on enzyme-altered foci and lipid peroxidation in livers of aflatoxin B1-initiated rats.
Topics: Aflatoxin B1; Animals; gamma-Glutamyltransferase; Glutathione Peroxidase; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Polychlorinated Biphenyls; Precancerous Conditions; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1992 |
Alterations in the structural gene and the expression of p53 in rat liver tumors induced by aflatoxin B1.
Topics: Aflatoxin B1; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; DNA; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Gene Rearrangement; Genes, Neoplasm; Genes, p53; Histones; Liver; Liver Neoplasms, Experimental; Male; Molecular Sequence Data; Oligonucleotide Probes; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Rats; Rats, Inbred F344; Restriction Mapping; Retinoblastoma Protein; RNA, Messenger; Sequence Homology; Tumor Suppressor Protein p53 | 1992 |
Inhibition of aflatoxin B1-induced gamma-glutamyltranspeptidase positive (GGT+) hepatic preneoplastic foci and tumors by low protein diets: evidence that altered GGT+ foci indicate neoplastic potential.
Topics: Aflatoxin B1; Animals; Dietary Proteins; Feeding Behavior; gamma-Glutamyltransferase; Histocytochemistry; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred F344 | 1992 |
Effect of dietary protein level on aflatoxin B1 actions in the liver of weanling rats.
Topics: Aflatoxin B1; Animals; Biotransformation; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Cytosol; Dietary Proteins; DNA; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Protein Deficiency; Rats; Rats, Inbred F344; Weaning | 1992 |
Aflatoxin B1 induced hepatocarcinogenesis in neonatal rats.
Topics: Aflatoxin B1; Age Factors; Animals; Animals, Newborn; Cell Division; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Longitudinal Studies; Male; Rats; Rats, Inbred Strains | 1992 |
Alterations in the p53 tumor suppressor gene in rat liver tumors induced by aflatoxin B1.
Topics: Aflatoxin B1; Animals; Blotting, Northern; Blotting, Southern; DNA Probes; Genes, Tumor Suppressor; Genome; Immunoblotting; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Precipitin Tests; Rats; Rats, Inbred F344; RNA, Neoplasm | 1992 |
Expression of rainbow trout apolipoprotein A-I genes in liver and hepatocellular carcinoma.
Topics: Aflatoxin B1; Amino Acid Sequence; Animals; Apolipoprotein A-I; Base Sequence; Blotting, Southern; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Neoplastic; Genome; Humans; Liver; Liver Neoplasms, Experimental; Molecular Sequence Data; Salmon; Sequence Alignment; Transcription, Genetic | 1992 |
Analysis of ras gene mutations in rainbow trout liver tumors initiated by aflatoxin B1.
Topics: Adenoma, Bile Duct; Aflatoxin B1; Aflatoxins; Alleles; Animals; Base Sequence; Cloning, Molecular; Exons; Gene Expression Regulation; Genes, ras; Liver Neoplasms; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutagenesis; Nucleic Acid Hybridization; Oligonucleotide Probes; Plasmids; Polymerase Chain Reaction; Species Specificity; Trout | 1991 |
Ultrastructure of hepatocellular neoplasms in aflatoxin B1 (AFB1)-initiated rainbow trout (Oncorhynchus mykiss).
Topics: Adenoma; Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Hepatocellular; Fish Diseases; Liver; Liver Neoplasms, Experimental; Microscopy, Electron; Trout | 1991 |
Reliability of a short-term test for hepatocarcinogenesis induced by aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; gamma-Glutamyltransferase; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred Strains | 1991 |
Protection against aflatoxin B1-induced hepatocarcinogenesis in F344 rats by 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz): predictive role for short-term molecular dosimetry.
Topics: Adenoma; Aflatoxin B1; Animals; DNA; gamma-Glutamyltransferase; Growth; Liver; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Survival Analysis; Thiones; Thiophenes | 1991 |
Thermogenesis, low-protein diets, and decreased development of AFB1-induced preneoplastic foci in rat liver.
Topics: Aflatoxin B1; Animals; Body Temperature Regulation; Body Weight; Caseins; Dietary Proteins; Dopamine; Eating; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Norepinephrine; Organ Size; Oxygen Consumption; Precancerous Conditions; Rats; Rats, Inbred F344 | 1991 |
Cytokeratin expression during AFB1-induced carcinogenesis.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Cell Transformation, Neoplastic; Cross Reactions; Cytoskeleton; Intermediate Filaments; Keratins; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 1990 |
Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin-albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats.
Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Biomarkers; DNA; Guanine; Liver Neoplasms, Experimental; Male; Protein Binding; Pyrazines; Rats; Rats, Inbred F344; Serum Albumin; Thiones; Thiophenes | 1992 |
[Effects of green tea extract on the development of aflatoxin B1-induced precancerous enzyme-altered hepatocellular foci in rats].
Topics: Aflatoxin B1; Animals; Histocytochemistry; Liver Neoplasms, Experimental; Male; Plant Extracts; Precancerous Conditions; Rats; Rats, Inbred Strains; Tea | 1991 |
The isolation and culture of DHBV-infected embryo and duckling hepatocytes and the effect of aflatoxin B1 or irradiation on these cells.
Topics: Aflatoxin B1; Aflatoxins; Animals; Blood Proteins; Cells, Cultured; DNA, Viral; Ducks; Embryo, Nonmammalian; Hepatitis B Virus, Duck; Liver; Liver Neoplasms; Liver Neoplasms, Experimental | 1991 |
Promotion of aflatoxin B1 carcinogenesis by the natural tumor modulator indole-3-carbinol: influence of dose, duration, and intermittent exposure on indole-3-carbinol promotional potency.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogenicity Tests; Carcinogens; Diet; Dose-Response Relationship, Drug; Drug Synergism; Indoles; Liver Neoplasms, Experimental; Time Factors; Trout | 1991 |
GTP-dependent membrane fusion during hepatocarcinogenesis and liver regeneration.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Division; DNA Replication; Guanosine Triphosphate; Intracellular Membranes; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Membrane Fusion; Microscopy, Electron; Microsomes, Liver; Rats; Rats, Inbred F344 | 1991 |
Effect of low protein diet on chronic aflatoxin B1-induced liver injury in rhesus monkeys.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Dietary Proteins; Histocytochemistry; Liver; Liver Neoplasms, Experimental; Macaca mulatta; Necrosis; Precancerous Conditions | 1991 |
Modulation of mycotoxin and nitrosamine carcinogenesis by indole-3-carbinol: quantitative analysis of inhibition versus promotion.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antioxidants; Carcinogens; Diethylnitrosamine; DNA; Indoles; Liver Neoplasms, Experimental; Trout | 1991 |
Effect of long-term feeding of nivalenol on aflatoxin B1-initiated hepatocarcinogenesis in mice.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Diet; Female; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mycotoxins; Sex Factors; Trichothecenes | 1991 |
Effect of subchronic aflatoxin exposure on growth and progression of Ehrlich's ascites tumor in mice.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Carcinoma, Ehrlich Tumor; Immunity; Liver Neoplasms, Experimental; Lymphoid Tissue; Macrophages; Male; Mice; Organ Size; Weight Gain | 1991 |
Suppression of aflatoxin B1-induced hepatotoxic lesions by crocetin (a natural carotenoid).
Topics: Aflatoxin B1; Animals; Carotenoids; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Rats; Rats, Inbred Strains; Vitamin A | 1991 |
Tumor promotion by the peroxisome proliferator nafenopin involving a specific subtype of altered foci in rat liver.
Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Carcinoma; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Nafenopin; Phenobarbital; Propionates; Rats; Rats, Inbred Strains; Time Factors | 1990 |
[Laboratory study on the relationship between drinking water and hepatoma--quantitative evaluation using hepatic gamma-GT method].
Topics: Aflatoxin B1; Aflatoxins; Animals; DDT; gamma-Glutamyltransferase; Image Processing, Computer-Assisted; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Water Supply | 1990 |
Characterization of c-Ki-ras and N-ras oncogenes in aflatoxin B1-induced rat liver tumors.
Topics: Aflatoxin B1; Aflatoxins; Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Codon; DNA; DNA, Neoplasm; Exons; Genes, ras; Liver; Liver Neoplasms, Experimental; Male; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Reference Values; Transfection | 1990 |
Contribution of aflatoxin B1 and hepatitis B virus infection in the induction of liver tumors in ducks.
Topics: Aflatoxin B1; Aflatoxins; Animals; DNA; DNA Damage; DNA, Viral; Ducks; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms; Liver Neoplasms, Experimental; Restriction Mapping; Survival Analysis | 1990 |
Effect of selenium on aflatoxin hepatocarcinogenesis in the rat.
Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Carcinogens; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains; Selenium | 1990 |
Establishment and characterization of cell lines (Kagura-1 and Kagura-2) from aflatoxin B1-induced rat hepatoma.
Topics: Aflatoxin B1; Aflatoxins; Animals; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 1990 |
[The effect of selenium on hepatocarcinogenesis of rats induced by aflatoxin B1].
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains; Selenium | 1990 |
Genetic analysis of aflatoxin B1 activation in rat hepatoma cells.
Topics: Aflatoxin B1; Aflatoxins; Animals; Base Sequence; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Drug Resistance; Liver Neoplasms, Experimental; Mixed Function Oxygenases; Molecular Sequence Data; Oligonucleotide Probes; Rats; RNA, Messenger; Tumor Cells, Cultured | 1990 |
Inhibition of hepatocarcinogenesis in mice by dietary methyl donors methionine and choline.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Choline; Diet; Life Tables; Liver Neoplasms, Experimental; Male; Methionine; Mice; Mixed Function Oxygenases | 1990 |
An exogenous albumin promoter can become silent in dedifferentiated hepatoma variants as well as intertypic hybrids.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Differentiation; Gene Expression Regulation; Hybrid Cells; In Vitro Techniques; L Cells; Liver Neoplasms, Experimental; Mice; Promoter Regions, Genetic; Rats; Serum Albumin; Transfection; Tumor Cells, Cultured | 1990 |
Protective activity of different hepatic cytosolic glutathione S-transferases against DNA-binding metabolites of aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Carcinoma, Hepatocellular; Cytosol; DNA; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Isoenzymes; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Microsomes, Liver; Polychlorinated Biphenyls; Rats; Sodium Dodecyl Sulfate; Trout | 1990 |
Effects of the irreversible ornithine decarboxylase inhibitor, alpha-difluoromethylornithine, aflatoxin B1, and choline deficiency on hepatocarcinogenesis.
Topics: Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Choline Deficiency; DNA; Eflornithine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; Rats, Inbred F344; Thymidine | 1985 |
Ovarian function during aflatoxin B1-induced hepatocarcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Body Weight; Dietary Proteins; Estradiol; Female; Genitalia, Female; Gonads; Liver Neoplasms; Liver Neoplasms, Experimental; Ovary; Progesterone; Rats; Rats, Inbred Strains | 1986 |
[Effect of six edible plants on the development of AFB1-induced gamma-glutamyltranspeptidase-positive hepatocyte foci in rats].
Topics: Aflatoxin B1; Aflatoxins; Animals; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Plants, Edible; Precancerous Conditions; Rats; Rats, Inbred Strains; Staining and Labeling; Tea | 1987 |
Effect of protein calorie malnutrition and cell replication on aflatoxin B1-induced hepatocarcinogenesis in rats.
Topics: Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Cell Division; Liver; Liver Neoplasms, Experimental; Male; Microscopy, Electron; Protein-Energy Malnutrition; Rats | 1987 |
Minimal dose and time protection by lindane (gamma-isomer of 1,2,3,4,5,6 hexachlorocyclohexane) against liver tumors induced by aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Female; Hexachlorocyclohexane; Liver; Liver Neoplasms, Experimental; Organ Size; Rats; Rats, Inbred BUF; Time Factors | 1989 |
Enhancement of aflatoxin B1-induced hepatocarcinogenesis in rats by partial hepatectomy.
Topics: Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Cocarcinogenesis; Hepatectomy; Liver Neoplasms, Experimental; Male; Microscopy, Electron; Rats; Rats, Inbred Strains | 1989 |
Enhancing effect of ethanol on aflatoxin B1-induced hepatocarcinogenesis in male ACI/N rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Ethanol; Iron; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred ACI; Staining and Labeling | 1989 |
[A study on primary liver cancer in tree shrews induced by human hepatitis B virus and aflatoxin B1].
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Female; Hepatitis B; Liver Neoplasms, Experimental; Male; Tupaiidae | 1989 |
[The study of aflatoxin B1-induced hepatocarcinogenesis of rats and mechanism of selenium's inhibitory effect on carcinogenesis].
Topics: Aflatoxin B1; Aflatoxins; Animals; Antineoplastic Agents; Carcinogens; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; Selenium | 1989 |
Primary and transplantable hepatomas induced by aflatoxin B1 in hypothyroid rats.
Topics: Adrenal Gland Neoplasms; Aflatoxin B1; Aflatoxins; Animals; Chronic Disease; gamma-Glutamyltransferase; Hyperplasia; Hypothyroidism; Kidney Neoplasms; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Neoplasm Transplantation; Organ Size; Precancerous Conditions; Rats; Rats, Inbred Strains; Thyroid Gland | 1989 |
Effect of dietary protein quality on development of aflatoxin B1-induced hepatic preneoplastic lesions.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Caseins; Dietary Proteins; Eating; gamma-Glutamyltransferase; Glutens; Liver Neoplasms, Experimental; Lysine; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Triticum; Weight Gain | 1989 |
Glutamine synthetase heterogeneous expression as a marker for the cellular lineage of preneoplastic and neoplastic liver populations.
Topics: 2-Acetylaminofluorene; Adenoma; Aflatoxin B1; Aflatoxins; Animals; Biomarkers, Tumor; Diethylnitrosamine; Glutamate-Ammonia Ligase; Immunoenzyme Techniques; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Reference Values | 1989 |
Different responses to phenobarbital promotion in the development of gamma-glutamyltranspeptidase-positive foci in the liver of rats initiated with diethylnitrosamine, N-hydroxy-2-acetyl-aminofluorene and aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; gamma-Glutamyltransferase; Hydroxyacetylaminofluorene; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats; Rats, Inbred F344 | 1985 |
The effects of selenium on the emergence of aflatoxin B1-induced enzyme-altered foci in rat liver.
Topics: Aflatoxin B1; Aflatoxins; Animals; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats; Rats, Inbred Strains; Selenium | 1985 |
Cytotoxicity of halogenated alkanes in primary cultures of rat hepatocytes from normal, partial hepatectomized, and preneoplastic/neoplastic liver.
Topics: Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Cell Survival; Cells, Cultured; gamma-Glutamyltransferase; Hepatectomy; Hydrocarbons, Halogenated; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Maleates; Proadifen; Rats; Rats, Inbred F344 | 1985 |
Tigroid cell foci and neoplastic nodules in the liver of rats treated with a single dose of aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Female; gamma-Glutamyltransferase; Histocytochemistry; Liver; Liver Neoplasms, Experimental; Microscopy, Electron; Precancerous Conditions; Rats; Rats, Inbred Strains | 1985 |
Dose-related inhibition of aflatoxin B1 induced hepatocarcinogenesis by the phenolic antioxidants, butylated hydroxyanisole and butylated hydroxytoluene.
Topics: Aflatoxin B1; Aflatoxins; Animals; Anisoles; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; gamma-Glutamyltransferase; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344 | 1986 |
Modulation of aflatoxin metabolism, aflatoxin-N7-guanine formation, and hepatic tumorigenesis in rats fed ethoxyquin: role of induction of glutathione S-transferases.
Topics: Aflatoxin B1; Aflatoxins; Animals; Bile; Butylated Hydroxyanisole; Butylated Hydroxytoluene; DNA; Enzyme Induction; Ethoxyquin; gamma-Glutamyltransferase; Glutathione Transferase; Guanine; Liver; Liver Neoplasms, Experimental; Male; Quinolines; Rats; Rats, Inbred F344 | 1986 |
Ethoxyquin alone induces preneoplastic changes in rat kidney whilst preventing induction of such lesions in liver by aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antigens, Neoplasm; Body Weight; Carboxylic Ester Hydrolases; Endopeptidases; Ethoxyquin; gamma-Glutamyltransferase; Glutathione Transferase; Histocytochemistry; Kidney; Kidney Neoplasms; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344 | 1987 |
Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antineoplastic Agents; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Heterocyclic Compounds; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Structure-Activity Relationship; Thiones; Thiophenes | 1987 |
Dietary protein level and aflatoxin B1-induced preneoplastic hepatic lesions in the rat.
Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Dietary Proteins; gamma-Glutamyltransferase; Histocytochemistry; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Time Factors | 1987 |
Metabolic basis for the protective effect of the antioxidant ethoxyquin on aflatoxin B1 hepatocarcinogenesis in the rat.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cytochrome P-450 Enzyme System; DNA; Ethoxyquin; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Quinolines; Rats; Rats, Inbred F344 | 1987 |
Morphometric and cytophotometric nuclear analysis of altered hepatocyte foci induced by N-nitrosomorpholine (NNM) and aflatoxin B1 (AFB1) in liver of Wistar rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Nucleus; Cell Transformation, Neoplastic; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1988 |
Modulation of hormonal induction of tyrosine aminotransferase and glucocorticoid receptors by aflatoxin B1 and sterigmatocystin in Reuber hepatoma cells.
Topics: Aflatoxin B1; Aflatoxins; Animals; Bucladesine; Cell Line; Centrifugation, Density Gradient; Cycloheximide; Enzyme Induction; Insulin; Liver Neoplasms, Experimental; Receptors, Glucocorticoid; Sterigmatocystin; Tyrosine Transaminase; Xanthenes | 1988 |
Expression of the c-Ha-ras and c-myc genes in aflatoxin B1-induced hepatocellular carcinomas.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA Restriction Enzymes; Gene Amplification; Liver Neoplasms, Experimental; Male; Nucleic Acid Hybridization; Oncogenes; Plasmids; Protein Biosynthesis; Rats; Rats, Inbred F344; Transcription, Genetic | 1986 |
New species of messenger RNA in aflatoxin B1 induced hepatocellular carcinoma.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; DNA; Liver; Liver Neoplasms, Experimental; Male; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; RNA, Heterogeneous Nuclear; RNA, Messenger | 1986 |
Fumaric acid enhances DNA synthesis of rat hepatocytes by counteracting the toxicities of mitomycin C and aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Nucleus; DNA; Fumarates; Liver; Liver Neoplasms, Experimental; Male; Mitomycin; Mitomycins; Rats | 1986 |
Enhancing effects of rodent malaria on aflatoxin B1-induced hepatic neoplasia.
Topics: Aflatoxin B1; Aflatoxins; Animals; Liver Neoplasms, Experimental; Malaria; Precancerous Conditions; Rats; Rats, Inbred BUF | 1986 |
Relationship between anaphase aberrations and carcinogenicity in the trout embryo microinjection assay.
Topics: Aflatoxin B1; Aflatoxins; Anaphase; Animals; Chromosome Aberrations; Embryo, Nonmammalian; Liver Neoplasms, Experimental; Mutagenicity Tests; Trout | 1986 |
Effects of antioxidants on aflatoxin-induced hepatic tumors in rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antioxidants; Ascorbic Acid; Female; Glutathione; Liver Neoplasms, Experimental; Methionine; Organ Size; Rats; Rats, Inbred Strains | 1987 |
Carcinogenicity of dietary aflatoxin M1 in male Fischer rats compared to aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Carcinogens; Diet; Intestinal Mucosa; Intestinal Neoplasms; Liver; Liver Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred F344 | 1987 |
Enhancement of carcinogenesis by the natural anticarcinogen indole-3-carbinol.
Topics: Aflatoxin B1; Aflatoxins; Animals; Brassica; Drug Synergism; Indoles; Liver Neoplasms, Experimental; Neoplasms, Experimental; Trout | 1987 |
The role of necrosis in hepatocellular proliferation and liver tumors.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzamides; Carcinoma; Choline Deficiency; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Necrosis; Rats; Rats, Inbred Strains; Selenium | 1987 |
Mechanism of cytotoxicity of aflatoxin B1: role of cytochrome P1-450.
Topics: Aflatoxin B1; Aflatoxins; Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Enzyme Induction; Lethal Dose 50; Liver Neoplasms, Experimental; Mice; Mutation | 1987 |
Characterization of c-Ki-ras oncogene alleles by direct sequencing of enzymatically amplified DNA from carcinogen-induced tumors.
Topics: Aflatoxin B1; Aflatoxins; Alleles; Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Enzyme Induction; Fibroblasts; Liver Neoplasms, Experimental; Male; Mice; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Rats; Rats, Inbred F344 | 1987 |
Transformation related expression of glutathione-S-transferase P in rat liver cells.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Enzyme Induction; Glutathione Transferase; Histocytochemistry; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344 | 1987 |
Statistical analysis of a carcinogen mixture experiment. I. Liver carcinogens.
Topics: Aflatoxin B1; Aflatoxins; Animals; Azo Compounds; Carcinogens; Cycasin; Drug Synergism; Female; Liver Neoplasms, Experimental; Male; Nitrosamines; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Statistics as Topic | 1987 |
Reduced levels of histones H1o and H1b, and unaltered content of methylated DNA in rainbow trout hepatocellular carcinoma chromatin.
Topics: 5-Methylcytosine; Aflatoxin B1; Aflatoxins; Animals; Chromatin; Cytosine; DNA; Histones; Liver; Liver Neoplasms, Experimental; Methylation; Transcription, Genetic; Trout; Vitellogenins | 1987 |
Reducing effects of rodent malaria on hepatic carcinogenesis induced by dietary aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Hematocrit; Liver; Liver Neoplasms, Experimental; Malaria; Male; Plasmodium berghei; Rats; Rats, Inbred BUF | 1988 |
Influence of aflatoxin B1 intoxication on duck livers with duck hepatitis B virus infection.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cocarcinogenesis; DNA, Viral; Ducks; Hepatitis B virus; Hepatitis, Viral, Animal; Liver; Liver Neoplasms, Experimental | 1988 |
The lectin-binding characteristics of aflatoxin B1 induced lesions in the rat liver.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Lectins; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344 | 1988 |
The induction of neoplastic lesions by aflatoxin-B1 in the Egyptian toad (Bufo regularis).
Topics: Aflatoxin B1; Aflatoxins; Animals; Bufonidae; Female; Kidney Neoplasms; Liver Neoplasms, Experimental; Male | 1988 |
Selection pressure and altered hepatocellular islands after a single injection of aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Butylated Hydroxyanisole; DNA; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Placenta; Precancerous Conditions; Rats; Rats, Inbred F344 | 1988 |
Liver foci formation during aflatoxin B1 carcinogenesis in the rat.
Topics: Aflatoxin B1; Aflatoxins; Algorithms; Animals; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Time Factors | 1988 |
Hepatocarcinogens induce gene mutations in rats in fibroblast-like cells from a subcutaneous granulation tissue.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Fibroblasts; Granulation Tissue; Liver Neoplasms, Experimental; Male; Mutation; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Vinyl Chloride | 1988 |
Efficient one-step selection of hepatoma cell variants of a variety of phenotypes by use of aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cytochrome P-450 Enzyme System; Liver Neoplasms, Experimental; Mixed Function Oxygenases; Phenotype; Rats; RNA, Messenger; Tumor Cells, Cultured | 1988 |
The ultrastructural features of aflatoxin B1-induced lesions in the rat liver.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Liver; Liver Neoplasms, Experimental; Male; Microscopy, Electron; Precancerous Conditions; Rats; Rats, Inbred F344 | 1988 |
[An observation on hepatocarcinogenesis in rat by longterm feeding with minimal doses of aflatoxin B1].
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Female; Hyperplasia; Liver Neoplasms, Experimental; Male; Rats | 1988 |
[Inhibition of aflatoxin B1-induced hepatocarcinogenesis by Rhizopus delemar].
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains; Rhizopus | 1988 |
Inhibition of aflatoxin B1-hepatocarcinogenesis in rats by beta-naphthoflavone.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Diet; Enzyme Induction; Flavonoids; Inactivation, Metabolic; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Vegetables | 1985 |
Iron exclusion from aflatoxin B1-induced hepatocellular carcinoma in rats.
Topics: Adenocarcinoma; Aflatoxin B1; Aflatoxins; Animals; Iron; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains | 1985 |