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aflatoxin b1 and Cell Transformation, Neoplastic

aflatoxin b1 has been researched along with Cell Transformation, Neoplastic in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199023 (41.07)18.7374
1990's13 (23.21)18.2507
2000's11 (19.64)29.6817
2010's8 (14.29)24.3611
2020's1 (1.79)2.80

Authors

AuthorsStudies
Clausen, N; Elgart, B; Foley, JF; Gerrish, K; Gladwell, W; Mav, D; Merrick, BA; Phadke, D; Shah, R; Tripodi, I; Weick, M1
Auerbach, SS; Mav, D; Merrick, BA; Phadke, DP; Shah, RR; Stiegelmeyer, SM; Tice, RR1
Huan, F; Lu, H; Meghan, C; Wang, SL; Wang, X; Wang, Y; Yang, X; Zhang, Z1
Chen, Z; Ji, J; Li, J; Wang, H; Yang, L1
Feng, Y; Guo, Z; Lian, J; Srinivas, S; Wang, S; Yang, W; Zhong, H; Zhuang, Z1
Gao, W; Ji, M; Sun, Z; Wang, C; Wang, H; Wang, SL; Wang, Y; Xu, H; Zhang, Y; Zhang, Z1
Accardi, R; Cosset, FL; Fusil, F; Gheit, T; Gruffat, H; Hernandez-Vargas, H; Le Calvez-Kelm, F; Manet, E; Sirand, C; Tommasino, M; Traverse-Glehen, A; Wild, CP1
Baumgartner, KJ; Dinkova-Kostova, AT; Egner, PA; Gribble, GW; Groopman, JD; Honda, T; Kensler, TW; Liby, K; Risingsong, R; Roebuck, BD; Royce, DB; Sporn, MB; Stephenson, KK; Sundararajan, C; Williams, CR; Yates, MS; Yore, MM; Yoshizawa, H1
Chen, L; Chen, W; Ji, W; Lai, Y; Li, D; Li, W; Lin, Y; Ma, R; Pang, Y; Tang, S; Wang, Q; Wei, Q; Xiao, Y; Yang, P; Zheng, Y; Zhuang, Z1
Dedon, PC; Doernte, AL; Essigmann, JM; Feng, Y; Fiala, JL; Fox, JG; Fry, RC; Lemon, SM; McFaline, JL; Raczynski, AR; Rogers, AB; Schauer, DB; Tannenbaum, SR; Theve, EJ; Weinman, SA; Williams, M1
Drouin, R; Lacoste, S; Rochette, PJ1
Anpo, M; Barrett, JC; Kanai, H; Kato, T; Kumakura, S; Tahara, H; Tamura, Y; Tsutsui, T; Yamamoto, A1
Farmer, PB; Sharma, RA1
Gopalan-Kriczky, P; Kimura, M; Lehmann, K; Lotlikar, PD1
Galendo, D; Lee, MK; Sabapathy, K; Tong, WM; Wang, ZQ1
Dixon, KR; Lian, M; Liu, Y; Qian, GS; Wan, SG; Yu, SZ1
Bailey, GS; Hendricks, JD; Orner, GA; Pereira, CB; Tilton, SC; Williams, DE1
Ban, KC; Cao, J; Chen, MW; Jiao, Y; Su, JJ; Yue, HY1
Cortesi, E; Donovan, PJ; Kakunaga, T; Rice, JM; Saffiotti, U1
Enwonwu, CO1
Boynton, AL; Kleine, LP; Whitfield, JF1
Curtis, G; Garland, H; Nesnow, S1
Amstad, PA; Cerutti, PA; Wang, TV1
Billings, PC; Heidelberger, C; Uwaifo, AO2
Frayssinet, C; Lafarge-Frayssinet, C; Morel-Chany, E; Trincal, G1
Schaeffer, WI1
Balwierz, PS; Oshiro, Y1
Abernethy, DJ; Boreiko, CJ; Frazelle, JH; Ragan, DL1
Blum, HE1
Aguilar, F; Cerutti, P; Hussain, P; Pourzand, C1
Casto, BC; Chen, J; Li, D; Milo, GE; Noyes, I; Shuler, C; Theil, K1
Yap, I1
Guengerich, FP; Kim, MS; Lowe, LG; Müller, M1
Benjamin, T; Hoang, T; Luo, LD; Wirth, PJ1
Dolan, PM; Egner, PA; Gange, SJ; Groopman, JD; Kensler, TW; Muñoz, A; Roebuck, BD; Rogers, AE1
Higginson, FM; Judah, DJ; Mandel, HG; Neal, GE; Riley, J; Sinha, S; Stanley, LA1
Sun, Z; Yuan, B1
Guengerich, FP1
Lotlikar, PD; Ning, Y; Qin, G1
Carthew, P; Green, JA; Heuillet, E; Manson, MM; Simpson, JL1
Dunn, JA; Faletto, MB; Gurtoo, HL; Kasper, SJ1
Ramesh, HP; Rati, ER; Shantha, T1
Ersing, N; Faletto, MB; Gurtoo, HL; Kouli, F; Maccubbin, AE; Vangalio, JA1
Faletto, MB; Gurtoo, HL; Koser, PL; Maccubbin, AE; Vangalio, JA1
Maeura, Y; Tanaka, T; Williams, GM1
Hockin, LJ; Neal, GE; Sinha, S1
Boix, J; Callaghan, R; Gil, R; Llombart-Bosch, A; Pellin, A1
Modali, R; Taub, JV; Vieira, W; Yang, GC; Yang, SS; Yasei, P1
Hayashi, K; Horikoshi, N; Kawamura, H; Makino, R; Morimura, S; Nemoto, K; Ohtsubo, K; Sugimura, T; Tashiro, F; Ueno, Y1
Lubet, RA; McCarvill, JT; Putman, DL; Schechtman, LM; Schwartz, JL1
del Campo, AA; McMahon, JB; Richards, WL; Song, MK; Thorgeirsson, SS1
Hanson, L; Lee, JJ; McMahon, G; Wogan, GN1
Davis, E; McMahon, G; Wogan, GN1
Manson, MM; Neal, GE; Power, C; Sinha, S; Webber, C1
Kiss, E; Kouri, RE; Lubet, RA; McCarvill, J; Nims, R; Schechtman, LM1

Reviews

6 review(s) available for aflatoxin b1 and Cell Transformation, Neoplastic

ArticleYear
[Mapping DNA damage to understand somatic mutagenesis].
    Medecine sciences : M/S, 2010, Volume: 26, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Codon; DNA; DNA Damage; DNA Methylation; DNA Repair; Genes, p53; Humans; Liver Neoplasms; Lung Neoplasms; Mutagenesis; Neoplasms, Radiation-Induced; Polymerase Chain Reaction; Skin Neoplasms; Sunlight; Ultraviolet Rays

2010
Biological relevance of adduct detection to the chemoprevention of cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aflatoxin B1; Anticarcinogenic Agents; Antioxidants; Biomarkers, Tumor; Carcinogens; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Clinical Trials as Topic; Deoxyguanosine; Diet; DNA; DNA Adducts; DNA Damage; DNA Repair; Humans; Immunochemistry; Male; Mass Spectrometry; Models, Chemical; Neoplasms; Oxidative Stress; Oxygen; Prostatic Neoplasms; Proteins; Risk; Sensitivity and Specificity

2004
[Hepatocellular carcinoma: molecular biology aspects].
    Zentralblatt fur Chirurgie, 1994, Volume: 119, Issue:11

    Topics: Aflatoxin B1; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Hepatitis B; Hepatitis C; Humans; Liver Cirrhosis, Alcoholic; Liver Neoplasms

1994
Mutagenesis of the H-ras protooncogene and the p53 tumor suppressor gene.
    Cancer research, 1994, Apr-01, Volume: 54, Issue:7 Suppl

    Topics: Aflatoxin B1; Base Sequence; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Codon; DNA Primers; Ethylnitrosourea; Genes, p53; Genes, ras; Humans; Liver Neoplasms; Molecular Sequence Data; Mutagenesis; Neoplasms; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proto-Oncogenes; Urinary Bladder Neoplasms

1994
Hepatocellular carcinoma--carcinogenesis updated.
    Singapore medical journal, 1995, Volume: 36, Issue:6

    Topics: Aflatoxin B1; Carcinogens, Environmental; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Hepatitis B; Humans; Liver; Liver Neoplasms; Risk Factors

1995
Chemical mechanisms of formation of DNA-carcinogen adducts, elucidation of potential of adducts for mutagenicity, and mechanisms of polymerase fidelity and mutation in the presence of adducts.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1997, Volume: 143

    Topics: Aflatoxin B1; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; DNA Adducts; DNA Polymerase II; DNA-Directed DNA Polymerase; Escherichia coli; Humans; Kinetics; Models, Biological; Mutagenesis; Substrate Specificity

1997

Other Studies

50 other study(ies) available for aflatoxin b1 and Cell Transformation, Neoplastic

ArticleYear
Whole exome and transcript profiling of liver following aflatoxin B1 exposure in rats.
    Journal of applied toxicology : JAT, 2023, Volume: 43, Issue:9

    Topics: Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Exome; Liver; Liver Neoplasms; Rats; Rats, Inbred F344

2023
RNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated rats.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; E2F1 Transcription Factor; Exons; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glucuronosyltransferase; High-Throughput Nucleotide Sequencing; Liver; Liver Neoplasms, Experimental; Male; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Principal Component Analysis; Rats; RNA, Messenger; Sequence Analysis, RNA; Transcriptome

2013
Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1.
    International journal of cancer, 2014, Apr-01, Volume: 134, Issue:7

    Topics: Aflatoxin B1; Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Ataxia Telangiectasia Mutated Proteins; bcl-2-Associated X Protein; Bronchi; Caspase 3; Cell Line; Cell Movement; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; DNA Adducts; DNA Repair; Epithelial Cells; Humans; Mice; Mice, Nude; Poly(ADP-ribose) Polymerases; Up-Regulation

2014
Transcriptome profiling of malignant transformed rat hepatic stem-like cells by aflatoxin B1.
    Neoplasma, 2014, Volume: 61, Issue:2

    Topics: Aflatoxin B1; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Neoplastic Stem Cells; Rats; Signal Transduction

2014
Genome-wide miRNA-profiling of aflatoxin B1-induced hepatic injury using deep sequencing.
    Toxicology letters, 2014, Apr-21, Volume: 226, Issue:2

    Topics: Aflatoxin B1; Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Computational Biology; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Markers; High-Throughput Nucleotide Sequencing; Liver; Liver Neoplasms; Male; MicroRNAs; Molecular Sequence Data; Rats; Rats, Inbred F344; Reproducibility of Results; RNA Precursors

2014
miR-138-1* regulates aflatoxin B1-induced malignant transformation of BEAS-2B cells by targeting PDK1.
    Archives of toxicology, 2016, Volume: 90, Issue:5

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; 3' Untranslated Regions; Aflatoxin B1; Aryl Hydrocarbon Hydroxylases; Binding Sites; Bronchi; Cell Line; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; RNA Interference; Signal Transduction; Time Factors; Transfection

2016
The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models.
    Carcinogenesis, 2015, Volume: 36, Issue:11

    Topics: Aflatoxin B1; Animals; B-Lymphocytes; Burkitt Lymphoma; Carcinogenesis; Cell Transformation, Neoplastic; Cells, Cultured; Environmental Exposure; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Male; Mice, Inbred NOD; Mice, SCID; Signal Transduction; Virus Activation; Virus Replication

2015
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.
    Cancer research, 2008, Aug-15, Volume: 68, Issue:16

    Topics: Administration, Oral; Aflatoxin B1; Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; DNA Adducts; Heme Oxygenase-1; Humans; Imidazoles; Leukemia; Liver Neoplasms; Macrophages; Male; Mice; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Phenanthrenes; Rats; Rats, Inbred F344; Reactive Oxygen Species

2008
Development of human cell models for assessing the carcinogenic potential of chemicals.
    Toxicology and applied pharmacology, 2008, Nov-01, Volume: 232, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aflatoxin B1; Animals; Benzo(a)pyrene; Bronchi; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cytochrome P-450 CYP1A1; Genes, myc; Genes, ras; Humans; Mice; Mice, Inbred BALB C; Nickel

2008
Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens.
    Gut, 2010, Volume: 59, Issue:1

    Topics: Adaptive Immunity; Aflatoxin B1; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Chemokines; Cocarcinogenesis; Female; Helicobacter hepaticus; Helicobacter Infections; Hepatitis B; Immunity, Innate; Interleukin-12 Subunit p40; Intestines; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Sex Factors; Signal Transduction; Th1 Cells

2010
Association of p16(INK4a) and pRb inactivation with immortalization of human cells.
    Carcinogenesis, 2002, Volume: 23, Issue:12

    Topics: 4-Nitroquinoline-1-oxide; Aflatoxin B1; Carcinogens; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cobalt Radioisotopes; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; DNA, Complementary; Fibroblasts; Humans; Keratinocytes; Oncogene Proteins, Viral; Phosphorylation; Repressor Proteins; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Telomerase; Telomere; Time Factors; Tumor Cells, Cultured; X-Rays

2002
Effect of diet on aflatoxin B1-DNA binding and aflatoxin B1-induced glutathione S-transferase placental form positive hepatic foci in the rat.
    Experimental & molecular medicine, 2004, Aug-31, Volume: 36, Issue:4

    Topics: Aflatoxin B1; Animals; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Diet; DNA; Glutathione Transferase; Hepatocytes; Liver Neoplasms; Microsomes, Liver; Rats

2004
Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice.
    International journal of cancer, 2006, Aug-15, Volume: 119, Issue:4

    Topics: Aflatoxin B1; Animals; Base Sequence; Cell Transformation, Neoplastic; DNA, Complementary; Humans; Liver Neoplasms; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Survival Rate; Tumor Suppressor Protein p53

2006
Hepatitis B virus x gene and cyanobacterial toxins promote aflatoxin B1-induced hepatotumorigenesis in mice.
    World journal of gastroenterology, 2006, May-21, Volume: 12, Issue:19

    Topics: Aflatoxin B1; Animals; Bacterial Toxins; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cyanobacteria Toxins; Dose-Response Relationship, Drug; Drug Synergism; Liver Neoplasms; Male; Marine Toxins; Mice; Mice, Transgenic; Microcystins; Peptides, Cyclic; Poisons; Polymerase Chain Reaction; Time Factors; Trans-Activators; Viral Regulatory and Accessory Proteins

2006
Gene expression analysis during tumor enhancement by the dietary phytochemical, 3,3'-diindolylmethane, in rainbow trout.
    Carcinogenesis, 2007, Volume: 28, Issue:7

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Dietary Supplements; Estradiol; Gene Expression Profiling; Indoles; Liver; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Oncorhynchus mykiss; Plant Preparations

2007
[Changes of beta catenin in carcinogenesis in rat livers induced by aflatoxin B1].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2007, Volume: 15, Issue:10

    Topics: Aflatoxin B1; Animals; beta Catenin; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Liver; Male; Rats; Rats, Sprague-Dawley

2007
Dose-response studies on neoplastic transformation of BALB/3T3 clone A31-1-1 cells by aflatoxin B1, benzidine, benzo[a]pyrene, 3-methylcholanthrene, and N-methyl-N'-nitro-N-nitrosoguanidine.
    Teratogenesis, carcinogenesis, and mutagenesis, 1983, Volume: 3, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzidines; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C

1983
The role of dietary aflatoxin in the genesis of hepatocellular cancer in developing countries.
    Lancet (London, England), 1984, Oct-27, Volume: 2, Issue:8409

    Topics: Aflatoxin B1; Aflatoxins; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Child; Cocarcinogenesis; Developing Countries; Dietary Proteins; DNA Replication; Food Contamination; Hepatitis B; Humans; Kwashiorkor; Liver; Liver Neoplasms; Microsomes, Liver; Mixed Function Oxygenases

1984
Ca2+/phospholipid-dependent protein kinase activity correlates to the ability of transformed liver cells to proliferate in Ca2+-deficient medium.
    Biochemical and biophysical research communications, 1983, Aug-30, Volume: 115, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Calcium Chloride; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Replication; Kinetics; Liver; Liver Neoplasms; Precancerous Conditions; Protein Kinase C; Protein Kinases; Rats

1983
Improved transformation of C3H10T1/2CL8 cells by direct- and indirect-acting carcinogens.
    Carcinogenesis, 1982, Volume: 3, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Methylnitronitrosoguanidine; Mice; Probability

1982
Removal of aflatoxin B1-DNA adducts and in vitro transformation in mouse embryo fibroblasts C3H/10T1 1/2.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carbon Radioisotopes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; DNA Replication; Embryo, Mammalian; Kinetics; Mice; Mice, Inbred C3H; Tritium

1983
Mutation of Chinese Hamster V79 cells and transformation and mutation of mouse fibroblast C3H/10T1/2 clone 8 cells by aflatoxin B1 and four other furocoumarins isolated from two Nigerian medicinal plants.
    Cancer research, 1983, Volume: 43, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Survival; Cell Transformation, Neoplastic; Coumarins; Cricetinae; Cricetulus; Fibroblasts; Furocoumarins; Lung; Methoxsalen; Mice; Mice, Inbred C3H; Nigeria; Plants, Medicinal

1983
Promoting effect of biliverdin for liver cells initiated by aflatoxin B1.
    Cancer letters, 1983, Volume: 18, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Bilirubin; Biliverdine; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Contact Inhibition; Liver; Rats; Rats, Inbred Strains

1983
Influence of benzoflavone on aflatoxin B1-induced cytotoxicity, mutation, and transformation of C3H/10T1/2 cells.
    Cancer research, 1983, Volume: 43, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Flavonoids; Mice; Mice, Inbred C3H; Mutagenicity Tests; Mutation

1983
The long-term culture of a diploid rat hepatocyte cell strain.
    Annals of the New York Academy of Sciences, 1980, Volume: 349

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzopyrenes; Carcinoma; Cell Division; Cell Line; Cell Transformation, Neoplastic; Diploidy; Karyotyping; Liver; Neoplasms, Experimental; Rats; Sarcoma; Time Factors

1980
Morphological transformation of C3H/10T1/2 CL8 cells by procarcinogens.
    Environmental mutagenesis, 1982, Volume: 4, Issue:2

    Topics: 2-Acetylaminofluorene; 2-Naphthylamine; 4-Nitroquinoline-1-oxide; Aflatoxin B1; Aflatoxins; Animals; Benz(a)Anthracenes; Biotransformation; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Drug Evaluation, Preclinical; Embryo, Mammalian; Mice; Time Factors

1982
Initiation of C3H/10T1/2 cell transformation by N-methyl-N'-nitro-N-nitrosoguanidine and aflatoxin B1.
    Carcinogenesis, 1982, Volume: 3, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Transformation, Neoplastic; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate

1982
Malignant conversion of chemically transformed normal human cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: Aflatoxin B1; Animals; Avian Sarcoma Viruses; Base Sequence; Blotting, Southern; Carcinogens; Carcinoma; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Mapping; Chromosomes, Human, Pair 7; DNA Primers; Epithelium; Gene Conversion; Humans; Infant, Newborn; Male; Methyl Methanesulfonate; Mice; Mice, Nude; Molecular Sequence Data; Polymerase Chain Reaction; Skin; Thiophenes; Transcription, Genetic; Transfection; Transplantation, Heterologous

1996
Two-dimensional polyacrylamide gel electrophoresis of cancer-associated proteins.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1997, Volume: 143

    Topics: Aflatoxin B1; Amino Acid Sequence; Animals; Autoradiography; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Electrophoresis, Polyacrylamide Gel; Epithelium; Female; Isoelectric Focusing; Liver; Molecular Sequence Data; Neoplasm Proteins; Oncogenes; Phosphoproteins; Phosphorus Radioisotopes; Rats; Rats, Inbred F344; Sequence Homology, Amino Acid; Tropomyosin

1997
Predictive value of molecular dosimetry: individual versus group effects of oltipraz on aflatoxin-albumin adducts and risk of liver cancer.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:8

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Cell Transformation, Neoplastic; DNA Adducts; Dose-Response Relationship, Drug; Drug Administration Schedule; Liver Neoplasms, Experimental; Male; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes

1997
Mutations associated with in vivo aflatoxin B1-induced carcinogenesis need not be present in the in vitro transformations by this toxin.
    Cancer letters, 1999, Apr-01, Volume: 137, Issue:2

    Topics: 3T3 Cells; Aflatoxin B1; Animals; Blotting, Southern; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; DNA Mutational Analysis; Epithelial Cells; Genes, p53; Genes, ras; Liver; Male; Mice; Mice, Nude; Mutagens; Mutation; Rats; Rats, Inbred F344; Sequence Analysis, DNA; Transfection

1999
[Transformation of rat hepatocytes in an in vitro primary culture by aflatoxin B1].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1997, Volume: 19, Issue:1

    Topics: Aflatoxin B1; Animals; Animals, Newborn; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cytochrome P-450 CYP1A2; Epithelial Cells; Genes, myc; Humans; Liver; Rats; Rats, Wistar; Transfection

1997
Forging the links between metabolism and carcinogenesis.
    Mutation research, 2001, Volume: 488, Issue:3

    Topics: Aflatoxin B1; Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; DNA; DNA Adducts; DNA Damage; Genetic Predisposition to Disease; History, 20th Century; Humans; Isoenzymes; Microsomes, Liver; Molecular Biology; Mutagenesis; Neoplasms; Structure-Activity Relationship

2001
Chemoprevention of aflatoxin B1-initiated and carbon tetrachloride-promoted hepatocarcinogenesis in the rat by green tea.
    Nutrition and cancer, 2000, Volume: 38, Issue:2

    Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Cell Division; Cell Transformation, Neoplastic; Fibrosis; gamma-Glutamyltransferase; Glutathione Transferase; Immunohistochemistry; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Tea

2000
Cytokeratin expression during AFB1-induced carcinogenesis.
    Carcinogenesis, 1990, Volume: 11, Issue:7

    Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Cell Transformation, Neoplastic; Cross Reactions; Cytoskeleton; Intermediate Filaments; Keratins; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Tumor Cells, Cultured

1990
Aflatoxin-transformed C3H/10T1/2 cells overexpress protein kinase C and have an altered response to phorbol ester treatments.
    Cancer research, 1992, Feb-15, Volume: 52, Issue:4

    Topics: Aflatoxin B1; Animals; Arachidonic Acid; Blotting, Western; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Division; Cell Line; Cell Transformation, Neoplastic; Isoenzymes; Kinetics; Mice; Mice, Inbred C3H; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug

1992
Effect of long term feeding and withdrawal of aflatoxin B1 and ochratoxin A on kidney cell transformation in albino rats.
    Indian journal of experimental biology, 1991, Volume: 29, Issue:9

    Topics: Administration, Oral; Aflatoxin B1; Animals; Carcinogens; Cell Transformation, Neoplastic; Kidney; Male; Ochratoxins; Rats; Rats, Inbred Strains

1991
Altered benzo[a]pyrene metabolism in C3H/10T1/2 cells transformed by aflatoxin B1 or 3-methylcholanthrene.
    Toxicology and applied pharmacology, 1990, Jun-15, Volume: 104, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA; DNA Adducts; gamma-Glutamyltransferase; Glucuronosyltransferase; Glutathione Transferase; Inactivation, Metabolic; Methylcholanthrene

1990
Induction of aryl hydrocarbon hydroxylase and DNA adduct formation in parental and carcinogen transformed C3H/10T1/2 clone 8 cells by benzo[a]pyrene.
    Cancer biochemistry biophysics, 1989, Volume: 10, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Clone Cells; Cytochrome P-450 Enzyme System; DNA; DNA Adducts; Enzyme Induction; Fibroblasts; Male; Mice; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains

1989
Dose-related inhibition of aflatoxin B1 induced hepatocarcinogenesis by the phenolic antioxidants, butylated hydroxyanisole and butylated hydroxytoluene.
    Carcinogenesis, 1986, Volume: 7, Issue:7

    Topics: Aflatoxin B1; Aflatoxins; Animals; Anisoles; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; gamma-Glutamyltransferase; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344

1986
A system for transformation of rat liver cells in vitro by acute treatment with aflatoxin.
    British journal of cancer, 1987, Volume: 55, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Liver; Methods; Mice; Mice, Nude; Rats

1987
Morphometric and cytophotometric nuclear analysis of altered hepatocyte foci induced by N-nitrosomorpholine (NNM) and aflatoxin B1 (AFB1) in liver of Wistar rats.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1988, Volume: 54, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Nucleus; Cell Transformation, Neoplastic; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1988
Dose dependency of aflatoxin B1 binding on human high molecular weight DNA in the activation of proto-oncogene.
    Environmental health perspectives, 1985, Volume: 62

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA; DNA Restriction Enzymes; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Humans; Kinetics; Liver; Mice; Mice, Inbred Strains; Molecular Weight; Nucleic Acid Hybridization; Protein Biosynthesis; Proto-Oncogene Mas; Proto-Oncogenes

1985
Expression of the c-Ha-ras and c-myc genes in aflatoxin B1-induced hepatocellular carcinomas.
    Biochemical and biophysical research communications, 1986, Jul-31, Volume: 138, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA Restriction Enzymes; Gene Amplification; Liver Neoplasms, Experimental; Male; Nucleic Acid Hybridization; Oncogenes; Plasmids; Protein Biosynthesis; Rats; Rats, Inbred F344; Transcription, Genetic

1986
Effects of 3-aminobenzamide on the induction of morphologic transformation by diverse compounds in Balb/3T3 cells in vitro.
    Carcinogenesis, 1986, Volume: 7, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzamides; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Ethyl Methanesulfonate; Kinetics; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C

1986
Differential effects of transforming growth factor-beta on proliferation of normal and malignant rat liver epithelial cells in culture.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Growth Inhibitors; Liver; Liver Neoplasms; Microscopy, Electron; Peptides; Rats; Transforming Growth Factors

1986
Identification of an activated c-Ki-ras oncogene in rat liver tumors induced by aflatoxin B1.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:24

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Gene Expression Regulation; GTP-Binding Proteins; Liver Neoplasms; Mice; Proto-Oncogene Proteins; Proto-Oncogenes; Rats; Transfection

1986
Characterization of c-Ki-ras oncogene alleles by direct sequencing of enzymatically amplified DNA from carcinogen-induced tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:14

    Topics: Aflatoxin B1; Aflatoxins; Alleles; Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Enzyme Induction; Fibroblasts; Liver Neoplasms, Experimental; Male; Mice; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Rats; Rats, Inbred F344

1987
Transformation related expression of glutathione-S-transferase P in rat liver cells.
    Carcinogenesis, 1987, Volume: 8, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Enzyme Induction; Glutathione Transferase; Histocytochemistry; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344

1987
A method for the amplification of chemically induced transformation in C3H/10T1/2 clone 8 cells: its use as a potential screening assay.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:3

    Topics: 2-Naphthylamine; Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Diethylnitrosamine; Dimethylnitrosamine; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344

1987