Compounds > aflatoxin b1
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aflatoxin b1 and Acute Liver Injury, Drug-Induced

aflatoxin b1 has been researched along with Acute Liver Injury, Drug-Induced in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-19907 (8.14)18.7374
1990's10 (11.63)18.2507
2000's23 (26.74)29.6817
2010's31 (36.05)24.3611
2020's15 (17.44)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Ji, J; Ma, X; Sun, J; Sun, X; Ye, Y1
Cheng, Y; Cui, Y; Guo, Y; Hu, B; Hua, H; Qian, H; Sheng, J; Zhang, W1
Cao, K; Feng, X; Jin, S; Liu, F; Liu, M; Shan, A; Wang, M; Wang, Y; Zhou, X1
Elgorashi, E; Foubert, K; Hermans, N; Makhuvele, R; Pieters, L; Verschaeve, L1
Deng, D; Feng, T; Iqbal, M; Kulyar, MF; Lin, H; Shen, Y; Wang, P; Wang, Y; Yan, Z; Zhu, D1
Gao, X; He, Y; Hu, L; Liu, H; Qiao, B; Rao, G; Ruan, Z; Su, Q; Tang, Z1
Cimbalo, A; Font, G; Frangiamone, M; Manyes, L; Thines, E; Yemelin, A1
Bai, H; Chang, X; Dong, W; Feng, C; Ma, Q; Wu, Z; Yang, J1
Abu Hafsa, SH; Elghandour, MMMY; Hassan, AA; Kanth Reddy, PR; Monroy, JC; Salem, AZM1
Chen, YY; He, CY; Lin, Y; Lin, YC; Lin, ZN; Wang, WH; Zhan, DL; Zhang, LY1
Alagawany, M; Farag, MR; Ismail, IE; Mahmoud, HK; Reda, FM1
Gilbert-Sandoval, I; Rietjens, IMCM; Wesseling, S1
Ahmed, AE; Al-Doaiss, AA; Al-Kahtani, MA; Alshehri, MA; El-Mekkawy, HI; Elmansi, AA; Shati, AA1
Bulgaru, C; Ciceu, A; Grosu, IA; Hermenean, A; Marin, DE; Pistol, GC; Taranu, I1
Hafez, SF; Ibrahim, KS; Mahdy-Abdallah, H; Saad-Hussein, A; Shaheen, W; Shahy, EM; Taha, MM1
Gong, B; Li, D; Ning, B; Tong, W; Xu, J1
Fan, T; Ma, W; Xie, Y1
Comakli, S; Kaya, E; Yılmaz, S1
Chen, JA; Feng, X; He, L; Huang, Y; Lin, H; Liu, W; Luo, J; Luo, Y; Pu, C; Qiu, Z; Shu, W; Tan, Y; Tian, Y; Wang, J; Wang, L; Wu, L; Xiao, G; Yang, X; Zeng, H; Zhang, R; Zheng, C1
Hamid, S; Han, M; Muhammad, I; Sun, X; Wang, X; Zhang, X1
Cui, XX; Han, MY; Li, W; Muhammad, I; Sun, XQ; Wang, XH; Zhang, XY1
Auerbach, SS; Bushel, PR; DeVito, MJ; Dunlap, PE; Ferguson, SS; Merrick, BA; Paules, RS; Ramaiahgari, SC; Rice, JR; Saddler, TO; Shah, RR; Sipes, NS1
Aya, HM; Mohgah, SA; Moubarz, G; Saad-Hussein, A; Wafaa, GS1
Fan, J; Fang, Y; Wang, S; Yang, C; Zhang, Y; Zhuang, Z1
Feng, Y; Guo, Z; Lian, J; Srinivas, S; Wang, S; Yang, W; Zhong, H; Zhuang, Z1
He, L; Ji, X; Li, R; Wang, X; Wei, W; Zhou, Y1
Coulombe, RA; El-Nezami, HS; McMahon, KW; Mendoza, KM; Monson, MS; Rawal, S; Reed, KM; Settlage, RE1
Krumm, CS; Lei, MY; Qi, DS; Sun, LH; Zhang, NY; Zhao, L1
Gao, X; Gu, CQ; Krumm, CS; Liu, J; Qi, DS; Qi, M; Song, WJ; Sun, LH; Zhang, NY; Zhao, L1
Ademuyiwa, O; Balogun, EA; Oluwafemi, F; Rotimi, OA; Rotimi, SO1
Ajiboye, TO; Oladiji, AT; Yakubu, MT1
Egner, PA; Kaneko, T; Kensler, TW; Mashimo, T; Morita, M; Taguchi, K; Takaku, M; Yamamoto, M1
Chishti, GA; Khan, JA; Khan, MS; Naseer, O; Omer, MO; Saleem, MU; Sohail, ML1
Gu, CQ; Guo, J; Krumm, CS; Liu, J; Qi, DS; Qi, M; Rajput, SA; Sun, LH; Zhang, NY; Zhao, L; Zhu, MK1
Jing, F; Mughal, MJ; Xi, P; Yi, Z1
Chang, SY; Chapron, B; Eaton, DL; Kavanagh, TJ; Kelly, EJ; Neumann, T; Shaffer, RM; Van Ness, KP; Voellinger, JL; White, CC1
Beam, JD; Daniel, GB; Gerhardt, LE; Grizzle, J; Hadley, TL; Jones, MP; Perrin, SL; Rotstein, DS; Saxton, AM1
Nayak, S; Sashidhar, RB1
Choi, KC; Chung, WT; Jang, YS; Kwon, JK; Lee, JC; Lee, SY; Park, SM; Yu, JY1
Choi, KC; Chung, WT; Jang, YS; Kwon, JK; Lee, JC; Park, SM; Yu, JY1
Castell, JV; Donato, MT; Gómez-Lechón, MJ; Pérez-Cataldo, G; Tolosa, L1
Bagnis, G; Cavaglieri, LR; Dalcero, AM; Magnoli, AP; Magnoli, CE; Marin, RH; Monge, MP; Nazar, FN1
Bai, F; Bai, S; Ding, X; Li, Y; Peng, X; Yang, J; Zhang, J; Zhang, K; Zhao, L1
Fan, Y; Gao, X; Ji, C; Lei, YP; Li, XY; Ma, QG; Zhang, JY; Zhao, LH; Zhou, T1
Coulombe, RA; Hall, JO; Klein, PJ; Van Vleet, TR1
Li, Y; Lu, H2
Kwon, SK; Shin, HS1
Abdel-Ghaffar, SK; El-Gibaly, I; Meki, AM1
BUTLER, WH1
Arslan, O; Karakilcik, AZ; Nazligul, Y; Vural, H; Zerin, M1
Galletti, S; Ravarotto, L; Sonzogni, O; Steidler, S; Tameni, M; Tedesco, D1
Carvalho, EC; Chiacchiera, SM; Dalcero, A; Ferrero, S; Magnoli, C; Miazzo, R; Peralta, MF; Rosa, CA; Salvano, M1
Farkas, D; Tannenbaum, SR1
Kanniappan, M; Nagaraj, M; Preetha, SP; Selvakumar, E; Varalakshmi, P1
Abdin, MZ; Javed, S; Naaz, F1
Changchien, CS; Chen, CH; Chen, PF; Hsu, MC; Hu, TH; Hung, CH; Lee, CM; Lee, SC; Lu, SN; Tung, HD; Wang, JH; Wang, MH1
Aller, WW; Asquith, RL; Bortell, R; Edds, GT; Simpson, CF1
Ademoyero, AA; Dalvi, RR1
Brünger, A; Greuel, E1
Edds, GT; Osuna, O1
Chopra, P; Duttagupta, S; Mathur, M; Mughal, S; Nayak, NC; Sathar, SA1
Ip, SP; Ko, KM; Li, PC; Mak, DH; Poon, MK1
Hong, SW; Park, C1
Aniya, Y; Gyamfi, MA1
Ha, TG; Kim, ND1
Chen, G; Harada, T; Sekijima, M; Tashiro, F; Tsutsumi, T; Ueno, Y; Yoshida, T; Yu, SZ1
Rao, VS; Souza, MF; Tomé, AR1
Campbell, TC; King, JM; Levitsky, DA; Lin, X1
Basaldella, E; Chiacchiera, SM; Dalcero, A; De Queiroz Carvalho, EC; Kikot, A; Magnoli, C; Miazzo, R; Palacio, G; Rosa, CA; Saenz, M1
Barton, CC; Barton, EX; Ganey, PE; Hill, DA; Roth, RA; Yee, SB1
Hashimoto, H; Summers, PM; Towner, RA1
Barton, CC; Ganey, PE; Roth, RA1
Rastogi, AK; Rastogi, R; Srivastava, AK1
Rastogi, AK; Rastogi, R; Srivastava, AK; Srivastava, M1
Odunola, OA; Uwalfo, AO1
Fouad, FM; Mamer, OA; Ruhenstroth-Bauer, G; Sauriol, F1
Damián, FJ; Jaramillo, F; Llamas, J; Loarca-Piña, MG; Martínez, A; Martínez, C; Ortíz, R; Quezada, T; Reyes, JL; Rodríguez, ML; Valdivia, AG; Yamamoto, L1
Ganey, PE; Luyendyk, JP; Roth, RA; Shores, KC1
Huff, JE1
Klaassen, CD; Liu, J; Madhu, C; Maziasz, TJ1
Brunden, MN; Nichols, NM; Ochoa, R; Rush, BD; Ruwart, MJ; Wilkinson, KF1
Glinsukon, T; Toskulkao, C1

Reviews

2 review(s) available for aflatoxin b1 and Acute Liver Injury, Drug-Induced

ArticleYear
Research progress on the protection and detoxification of phytochemicals against aflatoxin B
    Toxicon : official journal of the International Society on Toxinology, 2021, Volume: 195

    Topics: Aflatoxin B1; Chemical and Drug Induced Liver Injury; Hepatitis; Humans; Liver; Liver Neoplasms; Phytochemicals; Protective Agents

2021
Carcinogenicity of ochratoxin A in experimental animals.
    IARC scientific publications, 1991, Issue:115

    Topics: Adenofibroma; Adenoma; Adult; Aflatoxin B1; Animals; Balkan Nephropathy; Bulgaria; Carcinogenicity Tests; Carcinoma; Carcinoma, Transitional Cell; Chemical and Drug Induced Liver Injury; Cocarcinogenesis; Comorbidity; Female; Hepatectomy; Humans; Hyperplasia; Incidence; Kidney; Kidney Neoplasms; Liver Diseases; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Middle Aged; Mycotoxins; Ochratoxins; Precancerous Conditions; Rats; Rats, Inbred F344; Romania; Species Specificity; Urologic Neoplasms; Yugoslavia

1991

Trials

7 trial(s) available for aflatoxin b1 and Acute Liver Injury, Drug-Induced

ArticleYear
Efficacy of some feed additives to attenuate the hepato-renal damage induced by aflatoxin B1 in rabbits.
    Journal of animal physiology and animal nutrition, 2020, Volume: 104, Issue:5

    Topics: Aflatoxin B1; Aluminum Silicates; Animal Feed; Animals; Chemical and Drug Induced Liver Injury; Diet; Dietary Supplements; Food Preservatives; Kidney Diseases; Methionine; Rabbits; Sorbic Acid

2020
Role of antioxidant supplementation in oxidant/antioxidant status and hepatotoxic effects due to aflatoxin B1 in wheat miller workers.
    Journal of complementary & integrative medicine, 2019, Jun-13, Volume: 16, Issue:4

    Topics: Adult; Aflatoxin B1; Antioxidants; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Dietary Supplements; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Oxidative Stress; Particulate Matter; Prospective Studies; Triticum; Zinc

2019
Response of the hepatic transcriptome to aflatoxin B1 in ducklings.
    Toxicon : official journal of the International Society on Toxinology, 2016, Mar-01, Volume: 111

    Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Ducks; Gene Expression Regulation; Liver; Male; Transcriptome

2016
Comparative Efficacy of Silymarin and Choline Chloride (Liver Tonics) in Preventing the Effects of Aflatoxin B1 in Bovine Calves.
    Polish journal of veterinary sciences, 2016, Sep-01, Volume: 19, Issue:3

    Topics: Aflatoxin B1; Animals; Cattle; Cattle Diseases; Chemical and Drug Induced Liver Injury; Choline; Food Contamination; Silymarin

2016
Effects of feeding corn naturally contaminated with aflatoxin B1 and B2 on hepatic functions of broilers.
    Poultry science, 2012, Volume: 91, Issue:11

    Topics: Aflatoxin B1; Aflatoxins; Animal Feed; Animals; Apoptosis; Body Weight; Chemical and Drug Induced Liver Injury; Chickens; Diet; Dose-Response Relationship, Drug; Food Contamination; Hepatocytes; Liver; Male; Poultry Diseases; Zea mays

2012
Protective effect of Bacillus subtilis ANSB060 on egg quality, biochemical and histopathological changes in layers exposed to aflatoxin B1.
    Poultry science, 2012, Volume: 91, Issue:11

    Topics: Aflatoxin B1; Animals; Bacillus subtilis; Chemical and Drug Induced Liver Injury; Chickens; Eggs; Female; Liver; Poultry Diseases; Probiotics; Tocopherols

2012
Efficacy of silymarin-phospholipid complex in reducing the toxicity of aflatoxin B1 in broiler chicks.
    Poultry science, 2004, Volume: 83, Issue:11

    Topics: Aflatoxin B1; Animal Feed; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chickens; Eating; Liver Diseases; Male; Phospholipids; Poultry Diseases; Silymarin

2004

Other Studies

77 other study(ies) available for aflatoxin b1 and Acute Liver Injury, Drug-Induced

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Application of triple co-cultured cell spheroid model for exploring hepatotoxicity and metabolic pathway of AFB1.
    The Science of the total environment, 2022, Feb-10, Volume: 807, Issue:Pt 1

    Topics: Aflatoxin B1; Chemical and Drug Induced Liver Injury; Coculture Techniques; Humans; Metabolic Networks and Pathways; Spheroids, Cellular

2022
The Intervention and Mechanism of Action for Aloin against Subchronic Aflatoxin B1 Induced Hepatic Injury in Rats.
    International journal of molecular sciences, 2021, Oct-27, Volume: 22, Issue:21

    Topics: Aflatoxin B1; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Disease Models, Animal; Down-Regulation; Emodin; Interleukin-1beta; Lipid Peroxidation; Liver; Male; Rats

2021
Curcumin mitigates aflatoxin B1-induced liver injury via regulating the NLRP3 inflammasome and Nrf2 signaling pathway.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 161

    Topics: Aflatoxin B1; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Chemical and Drug Induced Liver Injury; Curcumin; Gene Expression Regulation; Hepatocytes; Inflammasomes; Liver; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Organ Size; Poisons

2022
Protective effects of methanolic leaf extracts of Monanthotaxis caffra against aflatoxin B1-induced hepatotoxicity in rats.
    The Onderstepoort journal of veterinary research, 2022, Mar-23, Volume: 89, Issue:1

    Topics: Aflatoxin B1; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Creatinine; Lactate Dehydrogenases; Liver; Male; Methanol; Plant Extracts; Rats; Rats, Sprague-Dawley; Rodent Diseases

2022
Hedyotis diffusa alleviate aflatoxin B1-induced liver injury in ducks by mediating Nrf2 signaling pathway.
    Ecotoxicology and environmental safety, 2023, Jan-01, Volume: 249

    Topics: Aflatoxin B1; Animals; Antioxidants; Body Weight; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Ducks; Hedyotis; Humans; Liver; NF-E2-Related Factor 2; Signal Transduction

2023
Curcumin attenuates AFB1-induced duck liver injury by inhibiting oxidative stress and lysosomal damage.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 172

    Topics: Aflatoxin B1; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Curcumin; Ducks; Liver; Oxidative Stress

2023
Fermented whey modulated AFB1 and OTA-induced hepatotoxicity and nephrotoxicity
    Toxicology mechanisms and methods, 2023, Volume: 33, Issue:6

    Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Female; Kidney Diseases; Male; Mycotoxins; Ochratoxins; Rats; Rats, Wistar; Sex Characteristics; Whey

2023
Aflatoxin B1-induced early developmental hepatotoxicity in larvae zebrafish.
    Chemosphere, 2023, Volume: 340

    Topics: Acetylcysteine; Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Fatty Liver; Larva; Zebrafish

2023
Dietary Supplementation with sodium bentonite and coumarin alleviates the toxicity of aflatoxin B
    Toxicon : official journal of the International Society on Toxinology, 2019, Dec-05, Volume: 171

    Topics: Aflatoxin B1; Animal Feed; Animals; Bentonite; Cecum; Chemical and Drug Induced Liver Injury; Coumarins; Diet; Food Contamination; Male; Rabbits

2019
Aflatoxin B1 enhances pyroptosis of hepatocytes and activation of Kupffer cells to promote liver inflammatory injury via dephosphorylation of cyclooxygenase-2: an in vitro, ex vivo and in vivo study.
    Archives of toxicology, 2019, Volume: 93, Issue:11

    Topics: Aflatoxin B1; Animals; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; HEK293 Cells; Hepatocytes; Humans; Inflammation; Interleukin-1beta; Kupffer Cells; Liver; Mice, Inbred C57BL; Phosphorylation; Primary Cell Culture; Pyroptosis

2019
Predicting the Acute Liver Toxicity of Aflatoxin B1 in Rats and Humans by an In Vitro-In Silico Testing Strategy.
    Molecular nutrition & food research, 2020, Volume: 64, Issue:13

    Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Hepatocytes; Humans; Liver; Models, Biological; Rats; Sensitivity and Specificity; Toxicity Tests, Acute

2020
Black tea and curcumin synergistically mitigate the hepatotoxicity and nephropathic changes induced by chronic exposure to aflatoxin-B1 in Sprague-Dawley rats.
    Journal of food biochemistry, 2020, Volume: 44, Issue:9

    Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Curcumin; Male; Rats; Rats, Sprague-Dawley; Tea

2020
Diet containing grape seed meal by-product counteracts AFB1 toxicity in liver of pig after weaning.
    Ecotoxicology and environmental safety, 2020, Oct-15, Volume: 203

    Topics: Aflatoxin B1; Animal Feed; Animals; Chemical and Drug Induced Liver Injury; Diet; Liver; Oxidative Stress; Seeds; Swine; Vitis; Weaning

2020
Hepatotoxicity of aflatoxin B1 and its oxidative effects in wood dust Egyptian exposed workers.
    Archives of environmental & occupational health, 2021, Volume: 76, Issue:8

    Topics: Adult; Aflatoxin B1; Antioxidants; Aspergillus; Chemical and Drug Induced Liver Injury; Cross-Sectional Studies; Dust; Egypt; Humans; Liver; Middle Aged; Occupational Diseases; Occupational Exposure; Oxidative Stress; Wood

2021
Impact of Sequencing Depth and Library Preparation on Toxicological Interpretation of RNA-Seq Data in a "Three-Sample" Scenario.
    Chemical research in toxicology, 2021, 02-15, Volume: 34, Issue:2

    Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Databases, Genetic; Gene Expression Profiling; Gene Library; Humans; RNA-Seq

2021
Vitamin E (α tocopherol) attenuates toxicity and oxidative stress induced by aflatoxin in rats.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2017, Volume: 26, Issue:6

    Topics: Aflatoxin B1; Animals; Antioxidants; Biomarkers; Cardiotoxicity; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Heart Diseases; Kidney; Kidney Diseases; Liver; Male; Myocytes, Cardiac; Oxidative Stress; Rats, Wistar; Vitamin E

2017
Interaction Effects of AFB1 and MC-LR Co-exposure with Polymorphism of Metabolic Genes on Liver Damage: focusing on SLCO1B1 and GSTP1.
    Scientific reports, 2017, 11-23, Volume: 7, Issue:1

    Topics: Aflatoxin B1; Aged; Chemical and Drug Induced Liver Injury; Female; Glutathione S-Transferase pi; Humans; Liver-Specific Organic Anion Transporter 1; Male; Marine Toxins; Microcystins; Middle Aged; Polymorphism, Genetic; Risk Factors

2017
Protective role of curcumin in ameliorating AFB
    Molecular biology reports, 2018, Volume: 45, Issue:5

    Topics: Aflatoxin B1; Animals; Apoptosis; Apoptosis Regulatory Proteins; Chemical and Drug Induced Liver Injury; Chickens; Curcumin; Dietary Supplements; Dose-Response Relationship, Drug; Gene Expression Regulation; Liver; Mitochondria; Oxidative Stress; Up-Regulation

2018
Water-soluble substances of wheat: a potential preventer of aflatoxin B1-induced liver damage in broilers.
    Poultry science, 2019, Jan-01, Volume: 98, Issue:1

    Topics: Aflatoxin B1; Animals; Apoptosis; Autophagy; Chemical and Drug Induced Liver Injury; Chickens; Hepatocytes; Inflammation; Liver; Pentosan Sulfuric Polyester; Protective Agents; Triticum

2019
The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling.
    Toxicological sciences : an official journal of the Society of Toxicology, 2019, Jun-01, Volume: 169, Issue:2

    Topics: Activation, Metabolic; Aflatoxin B1; Benchmarking; Benzo(a)pyrene; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Hepatocytes; High-Throughput Nucleotide Sequencing; Humans; Transcriptome

2019
The role of NAD(+)-dependent isocitrate dehydrogenase 3 subunit α in AFB1 induced liver lesion.
    Toxicology letters, 2014, Jan-30, Volume: 224, Issue:3

    Topics: Aflatoxin B1; Animals; Annexin A5; Base Sequence; Blotting, Western; Carcinogens; Cells, Cultured; Chemical and Drug Induced Liver Injury; Electrophoresis, Polyacrylamide Gel; Fluorescein-5-isothiocyanate; Humans; Hydrogen Peroxide; Isocitrate Dehydrogenase; Liver; Male; Mice; Molecular Sequence Data; Oncogene Protein v-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Species Specificity

2014
Genome-wide miRNA-profiling of aflatoxin B1-induced hepatic injury using deep sequencing.
    Toxicology letters, 2014, Apr-21, Volume: 226, Issue:2

    Topics: Aflatoxin B1; Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Computational Biology; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Markers; High-Throughput Nucleotide Sequencing; Liver; Liver Neoplasms; Male; MicroRNAs; Molecular Sequence Data; Rats; Rats, Inbred F344; Reproducibility of Results; RNA Precursors

2014
Evaluation of toxicological impacts on Sprague-Dawley rat by successively low dose of aflatoxin B1.
    Journal of the science of food and agriculture, 2014, Volume: 94, Issue:14

    Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Food Contamination; Kidney Diseases; Rats; Rats, Sprague-Dawley

2014
Response of the hepatic transcriptome to aflatoxin B1 in domestic turkey (Meleagris gallopavo).
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Aflatoxin B1; Animals; Apoptosis; Aspergillus; Cell Cycle; Chemical and Drug Induced Liver Injury; Gene Expression Profiling; Glycoproteins; Lactobacillus; Lipid Metabolism; Lipoprotein Lipase; Liver; Male; Methionine Adenosyltransferase; Poultry Diseases; Probiotics; Proto-Oncogene Proteins c-mdm2; Transcriptome; Turkeys

2014
Hepatotoxic effects of mycotoxin combinations in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 74

    Topics: Aflatoxin B1; Alanine Transaminase; Animals; Antioxidants; Apoptosis Regulatory Proteins; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Interactions; Female; Growth; Liver Function Tests; Malondialdehyde; Mice; Mycotoxins; Organ Size; Serum Albumin; Trichothecenes; Zearalenone

2014
Coexistence of Aflatoxicosis with Protein Malnutrition Worsens Hepatic Oxidative Damage in Rats.
    Journal of biochemical and molecular toxicology, 2016, Volume: 30, Issue:6

    Topics: Aflatoxin B1; Animals; Body Weight; Caloric Restriction; Caspase 3; Catalase; Chemical and Drug Induced Liver Injury; Diet, Protein-Restricted; Female; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Liver; Male; Oxidative Stress; Peroxidase; Rats; Signal Transduction; Superoxide Dismutase; Tumor Suppressor Protein p53

2016
Lophirones B and C prevent aflatoxin B1-induced oxidative stress and DNA fragmentation in rat hepatocytes.
    Pharmaceutical biology, 2016, Volume: 54, Issue:10

    Topics: Administration, Oral; Aflatoxin B1; Animals; Antioxidants; Biomarkers; Chalcones; Chemical and Drug Induced Liver Injury; Cytoprotection; DNA Fragmentation; Drug Administration Schedule; Hepatocytes; Lipid Peroxidation; Liver Function Tests; Male; Oxidative Stress; Rats; Rats, Wistar; Silymarin; Time Factors

2016
Generation of a New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B1 Toxicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 152, Issue:1

    Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; DNA Adducts; Gene Editing; Gene Expression Profiling; Genetic Predisposition to Disease; Imidazoles; Inactivation, Metabolic; Liver; Male; Mice, Inbred C57BL; Mice, Knockout; Mutation; NF-E2-Related Factor 2; Oleanolic Acid; Oligonucleotide Array Sequence Analysis; Phenotype; Rats, Inbred F344; Rats, Transgenic

2016
Curcumin Prevents Aflatoxin B₁ Hepatoxicity by Inhibition of Cytochrome P450 Isozymes in Chick Liver.
    Toxins, 2016, 11-10, Volume: 8, Issue:11

    Topics: Aflatoxin B1; Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Chickens; Curcumin; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA Adducts; Isoenzymes; Liver; Male; Microsomes, Liver; RNA, Messenger

2016
Aflatoxin B1 invokes apoptosis via death receptor pathway in hepatocytes.
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: Aflatoxin B1; Animals; Apoptosis; Apoptosis Regulatory Proteins; Chemical and Drug Induced Liver Injury; Chickens; Gene Expression Regulation; Hepatocytes; Liver; Receptors, Death Domain; Signal Transduction; Time Factors

2017
Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 40

    Topics: Adult; Aflatoxin B1; Animals; Cell Culture Techniques; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Child; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Drug Evaluation, Preclinical; Female; Hepatocyte Nuclear Factor 4; Hepatocytes; Humans; Male; Middle Aged; Rats; Toxicity Tests; Young Adult

2017
Effects of dietary milk thistle on blood parameters, liver pathology, and hepatobiliary scintigraphy in white carneaux pigeons (Columba livia) challenged with B1 aflatoxin.
    Journal of avian medicine and surgery, 2009, Volume: 23, Issue:2

    Topics: Aflatoxin B1; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chemical and Drug Induced Liver Injury; Columbidae; Diet; Liver Diseases; Radionuclide Imaging; Silybum marianum

2009
Metabolic intervention of aflatoxin B1 toxicity by curcumin.
    Journal of ethnopharmacology, 2010, Feb-17, Volume: 127, Issue:3

    Topics: Aflatoxin B1; Albumins; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Curcuma; Curcumin; Dietary Supplements; DNA Adducts; Enzymes; Guanine; Inactivation, Metabolic; Liver; Male; Phytotherapy; Plant Extracts; Rats

2010
Inhibitory effects of quercetin on aflatoxin B1-induced hepatic damage in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:10

    Topics: Aflatoxin B1; Animals; Body Weight; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Flavonols; Glutathione; Humans; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Organ Size; Quercetin; Reactive Oxygen Species

2010
Chemoprevention of a flavonoid fraction from Rhus verniciflua Stokes on aflatoxin B1-induced hepatic damage in mice.
    Journal of applied toxicology : JAT, 2011, Volume: 31, Issue:2

    Topics: Aflatoxin B1; Animals; Antioxidants; Cell Survival; Chemical and Drug Induced Liver Injury; Flavonoids; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Immunoglobulin Isotypes; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Plant Extracts; Random Allocation; Reactive Oxygen Species; Rhus; Superoxide Dismutase

2011
Upgrading cytochrome P450 activity in HepG2 cells co-transfected with adenoviral vectors for drug hepatotoxicity assessment.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:8

    Topics: Adenoviridae; Aflatoxin B1; Aryl Hydrocarbon Hydroxylases; Calcium; Cell Survival; Chemical and Drug Induced Liver Injury; Citric Acid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Genetic Vectors; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Models, Biological; Rotenone; Transfection

2012
Combined effects of aflatoxin B1 and corticosterone treatment on selected performance indices and liver histopathology in Japanese quail.
    Poultry science, 2012, Volume: 91, Issue:2

    Topics: Aflatoxin B1; Animal Feed; Animals; Chemical and Drug Induced Liver Injury; Corticosterone; Coturnix; Female; Food Contamination; Liver; Male; Poultry Diseases; Stress, Physiological

2012
Dietary butylated hydroxytoluene protects against aflatoxicosis in Turkeys.
    Toxicology and applied pharmacology, 2002, Jul-01, Volume: 182, Issue:1

    Topics: Aflatoxin B1; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Butylated Hydroxytoluene; Chemical and Drug Induced Liver Injury; Creatine Kinase; Histocytochemistry; L-Lactate Dehydrogenase; Liver Diseases; Male; Organ Size; Poultry Diseases; Random Allocation; Turkeys

2002
Effects of bicyclol on aflatoxin B1 metabolism and hepatotoxicity in rats.
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:10

    Topics: Aflatoxin B1; Animals; Biphenyl Compounds; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Drug Interactions; Inactivation, Metabolic; Male; Rats; Rats, Wistar

2002
Effects of dimethyl diphenyl bicarboxylate on the metabolism and hepatotoxicity of aflatoxin B1 in rats.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:10

    Topics: Aflatoxin B1; Aflatoxin M1; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dioxoles; Disease Models, Animal; Male; Microsomes, Liver; Protective Agents; Rats

2002
Synthesis of allylthiopyridazine derivatives and inhibition of aflatoxin B1-induced hepatotoxicity in rats.
    Archives of pharmacal research, 2003, Volume: 26, Issue:5

    Topics: Aflatoxin B1; Alanine Transaminase; Allyl Compounds; Animals; Aspartate Aminotransferases; Body Weight; Chemical and Drug Induced Liver Injury; Enzyme Activation; Glutathione Transferase; Liver; Male; Organ Size; Pyridazines; Rats; Rats, Sprague-Dawley

2003
Novel B melatonin-loaded chitosan microcapsules: in vitro characterization and antiapoptosis efficacy for aflatoxin B1-induced apoptosis in rat liver.
    International journal of pharmaceutics, 2003, Jul-09, Volume: 260, Issue:1

    Topics: Administration, Oral; Aflatoxin B1; Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Chitin; Chitosan; Delayed-Action Preparations; Dioctyl Sulfosuccinic Acid; Drug Carriers; Free Radical Scavengers; Kinetics; Liver; Male; Melatonin; Microspheres; Oxidative Stress; Pectins; Rats; Rats, Sprague-Dawley; Sodium Dodecyl Sulfate; Surface Properties; Surface-Active Agents; Water; Zinc

2003
ACUTE TOXICITY OF AFLATOXIN B-1 IN RATS.
    British journal of cancer, 1964, Volume: 18

    Topics: Adrenal Glands; Aflatoxin B1; Aflatoxins; Arachis; Carcinogens; Chemical and Drug Induced Liver Injury; Hepatitis; Kidney; Liver; Lung; Necrosis; Pathology; Rats; Research; Toxicology

1964
Effects of vitamin C and E on liver enzymes and biochemical parameters of rabbits exposed to aflatoxin B1.
    Veterinary and human toxicology, 2004, Volume: 46, Issue:4

    Topics: Aflatoxin B1; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Female; Rabbits; Vitamin E

2004
Efficacy of sodium bentonite as a detoxifier of broiler feed contaminated with aflatoxin and fumonisin.
    Poultry science, 2005, Volume: 84, Issue:1

    Topics: Aflatoxin B1; Animal Feed; Animals; Bentonite; Chemical and Drug Induced Liver Injury; Chickens; Diet; Food Contamination; Fumonisins; Intestinal Absorption; Liver; Liver Diseases; Organ Size; Poultry Diseases

2005
Characterization of chemically induced hepatotoxicity in collagen sandwiches of rat hepatocytes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 85, Issue:2

    Topics: Acetaminophen; Aflatoxin B1; Albumins; Animals; Benzoquinones; Blotting, Western; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Collagen; Cytochrome P-450 Enzyme System; Dimethylformamide; Glucuronides; Glutathione; Hepatocytes; Isoenzymes; L-Lactate Dehydrogenase; Mass Spectrometry; Oxazines; Rats; Sulfates; Urea; Vinyl Compounds; Xanthenes

2005
Lupeol ameliorates aflatoxin B1-induced peroxidative hepatic damage in rats.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2006, Volume: 143, Issue:3

    Topics: Aflatoxin B1; Animals; Antioxidants; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Transferase; Lipid Peroxidation; Liver; Liver Diseases; Male; Oxidoreductases; Pentacyclic Triterpenes; Rats; Rats, Wistar; Silymarin; Triterpenes; Vitamin E

2006
Hepatoprotective effect of ethanolic extract of Phyllanthus amarus Schum. et Thonn. on aflatoxin B1-induced liver damage in mice.
    Journal of ethnopharmacology, 2007, Sep-25, Volume: 113, Issue:3

    Topics: Aflatoxin B1; Animals; Catalase; Chemical and Drug Induced Liver Injury; Ethanol; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Liver Diseases; Male; Mice; Phyllanthus; Phytotherapy; Plant Extracts; Protective Agents; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2007
Aflatoxin exposure and hepatitis C virus in advanced liver disease in a hepatitis C virus endemic area in Taiwan.
    The American journal of tropical medicine and hygiene, 2007, Volume: 77, Issue:4

    Topics: Aflatoxin B1; Aflatoxins; Aged; Albumins; Chemical and Drug Induced Liver Injury; Data Collection; Disease Progression; Endemic Diseases; Environmental Exposure; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Liver Diseases; Male; Middle Aged; Risk Factors; Taiwan

2007
Acute experimentally induced aflatoxicosis in the weanling pony.
    American journal of veterinary research, 1983, Volume: 44, Issue:11

    Topics: Acute Disease; Aflatoxin B1; Aflatoxins; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Female; gamma-Glutamyltransferase; Horse Diseases; Horses; Liver; Liver Diseases; Male; Necrosis

1983
Efficacy of activated charcoal and other agents in the reduction of hepatotoxic effects of a single dose of aflatoxin B1 in chickens.
    Toxicology letters, 1983, Volume: 16, Issue:1-2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Aspartate Aminotransferases; Benzphetamine; Charcoal; Chemical and Drug Induced Liver Injury; Chickens; Cytochrome P-450 Enzyme System; Female; Liver Diseases; Male; Microsomes, Liver

1983
[Liver changes in salmon caused by aflatoxin B1].
    Tierarztliche Praxis, 1983, Volume: 11, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Fish Diseases; Liver; Liver Diseases; Salmon

1983
Toxicology of aflatoxin B1, warfarin, and cadmium in young pigs: clinical chemistry and blood coagulation.
    American journal of veterinary research, 1982, Volume: 43, Issue:8

    Topics: Aflatoxin B1; Aflatoxins; Animal Feed; Animals; Blood Proteins; Blood Urea Nitrogen; Cadmium; Cadmium Poisoning; Carcinogens; Chemical and Drug Induced Liver Injury; Liver Diseases; Male; Swine; Swine Diseases; Warfarin

1982
The nature and significance of liver cell vacuolation following hepatocellular injury--an analysis based on observations on rats rendered tolerant to hepatotoxic damage.
    Virchows Archiv : an international journal of pathology, 1996, Volume: 428, Issue:6

    Topics: Adaptation, Physiological; Aflatoxin B1; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Carcinogens; Chemical and Drug Induced Liver Injury; Cytoplasm; Drug Tolerance; Fasting; Formic Acid Esters; Glycogen; Liver; Liver Diseases; Male; Microscopy, Electron; Rats; Rats, Wistar; Vacuoles

1996
Effect of a lignan-enriched extract of Schisandra chinensis on aflatoxin B1 and cadmium chloride-induced hepatotoxicity in rats.
    Pharmacology & toxicology, 1996, Volume: 78, Issue:6

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Cadmium Chloride; Carcinogens; Chemical and Drug Induced Liver Injury; Cytosol; Female; Glutathione; Male; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Vitamin E

1996
The effect of aflatoxin B1 on the expression of early response genes and transforming growth factor-alpha in CCl4 induced rat liver injury.
    Yonsei medical journal, 1997, Volume: 38, Issue:3

    Topics: Aflatoxin B1; Animals; Carbon Tetrachloride; Carcinogens; Chemical and Drug Induced Liver Injury; Gene Expression; Genes, Immediate-Early; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor alpha

1997
Medicinal herb, Thonningia sanguinea protects against aflatoxin B1 acute hepatotoxicity in Fischer 344 rats.
    Human & experimental toxicology, 1998, Volume: 17, Issue:8

    Topics: Aflatoxin B1; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Injections, Intraperitoneal; Liver Function Tests; Male; Mixed Function Oxygenases; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred F344

1998
2-(allylthio)pyrazine inhibition of aflatoxin B1-induced hepatotoxicity in rats: inhibition of cytochrome P450 2B- and 3A2-mediated bioactivation.
    Research communications in molecular pathology and pharmacology, 1998, Volume: 102, Issue:1

    Topics: Aflatoxin B1; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; DNA Adducts; Enzyme Inhibitors; Lipid Peroxidation; Liver; Liver Function Tests; Male; Pyrazines; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Transaminases

1998
Enhancement of glutathione S-transferase placental-form positive liver cell foci development by microcystin-LR in aflatoxin B1-initiated rats.
    Carcinogenesis, 1999, Volume: 20, Issue:1

    Topics: Aflatoxin B1; Animals; Bacterial Toxins; Biomarkers; Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Drug Synergism; Glutathione Transferase; Hepatectomy; Isoenzymes; Liver; Liver Diseases; Male; Marine Toxins; Microcystins; Organ Specificity; Peptides, Cyclic; Placenta; Precancerous Conditions; Rats; Rats, Inbred F344

1999
Inhibition by the bioflavonoid ternatin of aflatoxin B1-induced lipid peroxidation in rat liver.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:2

    Topics: Aflatoxin B1; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Carcinogens; Chemical and Drug Induced Liver Injury; Flavonoids; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Plants, Medicinal; Rats; Rats, Wistar; Vitamin E

1999
The promotion effect of anorectic drugs on aflatoxin B(1)-induced hepatic preneoplastic foci.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Adipose Tissue, Brown; Aflatoxin B1; Amphetamine; Animals; Appetite Depressants; Biomarkers; Body Temperature Regulation; Carcinogens; Chemical and Drug Induced Liver Injury; Cocarcinogenesis; Dopamine; Drug Synergism; Eating; Energy Metabolism; Fenfluramine; Fluoxetine; gamma-Glutamyltransferase; Growth Disorders; Hypothyroidism; Liver Diseases; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Serotonin; Weight Loss

1999
Efficacy of synthetic zeolite to reduce the toxicity of aflatoxin in broiler chicks.
    Poultry science, 2000, Volume: 79, Issue:1

    Topics: Adsorption; Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Chickens; Liver; Liver Diseases; Male; Organ Size; Poultry Diseases; Vacuoles; Weight Gain; Zeolites

2000
Bacterial lipopolysaccharide exposure augments aflatoxin B(1)-induced liver injury.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 55, Issue:2

    Topics: 5'-Nucleotidase; Aflatoxin B1; Alanine Transaminase; Alkaline Phosphatase; Animals; Apoptosis; Aspartate Aminotransferases; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Synergism; Escherichia coli; gamma-Glutamyltransferase; In Situ Nick-End Labeling; Lipopolysaccharides; Liver; Male; Rats; Rats, Sprague-Dawley

2000
Non-invasive in vivo magnetic resonance imaging assessment of acute aflatoxin B1 hepatotoxicity in rats.
    Biochimica et biophysica acta, 2000, Jul-26, Volume: 1475, Issue:3

    Topics: Aflatoxin B1; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Liver; Magnetic Resonance Imaging; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Time Factors

2000
Lipopolysaccharide augments aflatoxin B(1)-induced liver injury through neutrophil-dependent and -independent mechanisms.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:1

    Topics: 5'-Nucleotidase; Aflatoxin B1; Alanine Transaminase; Alkaline Phosphatase; Animals; Apoptosis; Aspartate Aminotransferases; Bile Ducts, Intrahepatic; Cell Count; Chemical and Drug Induced Liver Injury; Drug Synergism; Escherichia coli; gamma-Glutamyltransferase; Hyperplasia; In Situ Nick-End Labeling; Injections, Intraperitoneal; Kupffer Cells; Lipopolysaccharides; Liver; Male; Neutrophils; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley

2000
Biochemical changes induced in liver and serum of aflatoxin B1-treated male wistar rats: preventive effect of picroliv.
    Pharmacology & toxicology, 2001, Volume: 88, Issue:2

    Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Cinnamates; Drug Interactions; Enzymes; Glutathione; Glycogen; Glycosides; Lipid Peroxidation; Liver; Male; Plant Extracts; Rats; Rats, Wistar; Vanillic Acid

2001
Hepatocurative effect of picroliv and silymarin against aflatoxin B1 induced hepatotoxicity in rats.
    Planta medica, 2000, Volume: 66, Issue:8

    Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Cinnamates; Glycosides; Male; Rats; Silymarin; Vanillic Acid

2000
Immune response to aflatoxin B1-histone H1 complex.
    African journal of medicine and medical sciences, 2000, Volume: 29, Issue:2

    Topics: Aflatoxin B1; Animals; Antibodies; Binding Sites, Antibody; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Evaluation, Preclinical; Histones; Immunotherapy; Immunotoxins; Liver Diseases; Male; Rats; Rats, Wistar; Vaccines, Synthetic

2000
Kinetics and mechanisms of hepatic acute phase response to subtotal partial hepatectomy and cultural impact on environmental hepatic end-stage liver injury in the homeless.
    Medical hypotheses, 2001, Volume: 56, Issue:6

    Topics: Acute-Phase Reaction; Aflatoxin B1; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Hepatectomy; Humans; Ill-Housed Persons; Liver Diseases; Rats

2001
Efficacy of N-acetylcysteine to reduce the effects of aflatoxin B1 intoxication in broiler chickens.
    Poultry science, 2001, Volume: 80, Issue:6

    Topics: Acetylcysteine; Aflatoxin B1; Alanine Transaminase; Animal Feed; Animals; Aspartate Aminotransferases; Blood Proteins; Body Weight; Chemical and Drug Induced Liver Injury; Chickens; Free Radical Scavengers; Glutathione; Glutathione Transferase; Kidney; Kidney Diseases; Liver; Liver Diseases; Male; Poultry Diseases; Random Allocation; Treatment Outcome

2001
Bacterial lipopolysaccharide exposure alters aflatoxin B(1) hepatotoxicity: benchmark dose analysis for markers of liver injury.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 68, Issue:1

    Topics: Aflatoxin B1; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Benchmarking; Bile Ducts, Intrahepatic; Chemical and Drug Induced Liver Injury; Cholestasis; Dose-Response Relationship, Drug; Drug Synergism; Escherichia coli; Injections, Intraperitoneal; Lipopolysaccharides; Liver; Male; No-Observed-Adverse-Effect Level; Rats; Rats, Sprague-Dawley

2002
The differential effects of hepatotoxicants on the sulfation pathway in rats.
    Toxicology and applied pharmacology, 1991, Sep-15, Volume: 110, Issue:3

    Topics: 1-Naphthylisothiocyanate; 1-Propanol; Aflatoxin B1; Alanine Transaminase; Animals; Arylsulfotransferase; Bromobenzenes; Cadmium; Cadmium Chloride; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytosol; Dichloroethylenes; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Phosphoadenosine Phosphosulfate; Propanols; Rats; Rats, Inbred Strains; Sulfates; Thioacetamide

1991
Hepatic protection by 16, 16-dimethyl prostaglandin E2 (DMPG) against acute aflatoxin B1-induced injury in the rat.
    Prostaglandins, 1989, Volume: 37, Issue:6

    Topics: 16,16-Dimethylprostaglandin E2; Aflatoxin B1; Aflatoxins; Animals; Chemical and Drug Induced Liver Injury; DNA; Dose-Response Relationship, Drug; Liver; Male; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains

1989
Hepatic lipid peroxidation and intracellular calcium accumulation in ethanol potentiated aflatoxin B1 toxicity.
    Journal of pharmacobio-dynamics, 1988, Volume: 11, Issue:3

    Topics: Aflatoxin B1; Aflatoxins; Animals; Calcium; Chemical and Drug Induced Liver Injury; Cytosol; Ethanol; Lipid Peroxides; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Inbred Strains; Time Factors

1988