aflatoxin-b and Poultry-Diseases

aflatoxin-b has been researched along with Poultry-Diseases* in 2 studies

Trials

1 trial(s) available for aflatoxin-b and Poultry-Diseases

ArticleYear
Effects of feeding corn naturally contaminated with aflatoxin B1 and B2 on hepatic functions of broilers.
    Poultry science, 2012, Volume: 91, Issue:11

    The purpose of this study was to evaluate the effects of feeding corn naturally contaminated with aflatoxin B(1) (AFB(1)) and aflatoxin B(2) (AFB(2)) on serum biochemical parameters, hepatic antioxidant enzyme activities, and pathological lesions of broilers. In total, 1,200 Cobb male broilers were randomly allocated into 5 treatments, with 8 replicates per treatment and 30 birds per replicate, in a 42-d experiment. The dietary treatments were as follows: control, 25, 50, 75, and 100% contaminated corn groups. Results showed that serum aspartate aminotransferase activity in the 75 and 100% contaminated groups were higher than that in the control group on d 21 (P < 0.05). Decreased content of hepatic total protein and increased activities of hepatic glutathione reductase and glutathione-S-transferase were observed as the percentage of contaminated corn increased (P < 0.05). The activity of superoxide dismutase and the content of hepatic malondialdehyde increased when the broilers were fed with more than 50% contaminated corn (P < 0.05). A reduction in glutathione peroxidase level was observed in the AFB(1)- and AFB(2)-contaminated groups on d 21 (P < 0.05). The average pathological lesion scores and apoptosis rate of liver cells increased as the concentration of dietary AFB(1) and AFB(2) increased. Ultrastructural changes were found in the livers of broilers fed 100% contaminated corn. In conclusion, diets containing AFB(1) and AFB(2) could induce pathological lesions in the livers, slightly change the serum biochemical parameters, and damage the hepatic antioxidant functions when the inclusion of AFB(1)- and AFB(2)-contaminated corn reached or exceeded 50%.

    Topics: Aflatoxin B1; Aflatoxins; Animal Feed; Animals; Apoptosis; Body Weight; Chemical and Drug Induced Liver Injury; Chickens; Diet; Dose-Response Relationship, Drug; Food Contamination; Hepatocytes; Liver; Male; Poultry Diseases; Zea mays

2012

Other Studies

1 other study(ies) available for aflatoxin-b and Poultry-Diseases

ArticleYear
Broiler aflatoxicosis with recovery after replacement of the contaminated diet.
    British poultry science, 1985, Volume: 26, Issue:1

    Broiler chickens were fed a diet containing 2057 and 1323 micrograms/kg feed of aflatoxins B1 and B2, respectively, for 35 d. Effects of aflatoxins on growth, food consumption, efficiency of food utilisation and manifestations of aflatoxicosis were compared with control birds at the end of the feeding trial and at 1, 2, 4, 8 and 16 d after replacing the contaminated feed. No difference in food consumption was observed between the controls and the aflatoxin-fed chickens, but efficiency of food utilisation was decreased from 2.2 for the controls to 2.4 g food/g gain for the group fed aflatoxins. Aflatoxins caused depressed growth and enlargement of the kidney, liver, heart and gall bladder. Haemorrhagic spots were present on the surface of the muscles and some of the livers. Most livers from aflatoxin-fed birds were pale and infiltrated with lipid. After withdrawal of the food containing aflatoxins, all apparent gross lesions of aflatoxicosis disappeared, with no evidence of any lesions 8 d after removal of the contaminated diet.

    Topics: Aflatoxin B1; Aflatoxins; Animal Feed; Animals; Chickens; Foodborne Diseases; Male; Organ Size; Organ Specificity; Poultry Diseases

1985