afdx 116 has been researched along with Muscle Contraction in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.52) | 18.7374 |
| 1990's | 30 (65.22) | 18.2507 |
| 2000's | 9 (19.57) | 29.6817 |
| 2010's | 4 (8.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buyukafsar, K; Cevik, OS; Koyuncu, DD; Sahin, L | 1 |
| Brenner, R; Herlihy, JT; Semenov, I; Wang, B | 1 |
| Kajioka, S; Naito, S; Seki, N; Shahab, N | 1 |
| Barnes, PJ; Brown, SM; Donnelly, LE; Koarai, A; Nicholson, AG; Sturton, RG | 1 |
| Althaus, H; Marti, M; Mevissen, M; Steiner, A | 1 |
| de Groat, WC; Ng, YK; Wu, HY | 1 |
| Cao, J; Hashiba, K; Kitazawa, T; Komori, S; Taneike, T; Unno, T; Wess, J; Yamada, M | 1 |
| Arreola, JL; Chávez, J; Flores-Soto, E; Montaño, LM; Segura, P; Vargas, MH | 1 |
| Mevissen, M; Meylan, M; Pfeiffer, JB; Portier, CJ; Steiner, A | 1 |
| Chiba, S; Nakane, T; Ren, LM | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Elzinga, CR; Meurs, H; Roffel, AF; Zaagsma, J | 2 |
| Dietrich, C; Kilbinger, H | 1 |
| Boselli, C; Grana, E | 1 |
| Gabelt, BT; Kaufman, PL; Poyer, JF | 1 |
| Imaizumi, Y; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Kotlikoff, MI; Kume, H; Mikawa, K; Takagi, K | 1 |
| Ehlert, FJ; Thomas, EA | 2 |
| Altiere, RJ; Roberts, J; Thompson, DC; Travis, DC | 1 |
| Greten, H; Mirau, S; Raedler, A; Sievers, J; von Schrenck, T | 1 |
| Baker, SA; Ehlert, FJ; Thomas, EA | 1 |
| Garssen, J; Gierveld, CM; Nijkamp, FP; Van der Vliet, H; Van Loveren, H | 1 |
| Garland, CJ; Hillier, K; Kerr, PM; Wallis, RM | 1 |
| Anderson, JW; Brundage, KL; Fisher, JT | 1 |
| Ehlert, FJ; Sawyer, GW | 2 |
| Mitchelson, F; Shen, A | 1 |
| Cohen, ML; Gomeza, J; Stengel, PW; Wess, J | 1 |
| Ehlert, FJ; Lambrecht, G; Sawyer, GW | 1 |
| Kwon, SC | 1 |
| Cohen, ML; Stengel, PW | 1 |
| Bloom, JW; Halonen, M; Mahesh, VK; Nunan, LM; Palmer, JD; Yamamura, HI | 1 |
| Daniel, EE; Janssen, LJ | 1 |
| Choo, LK; Mitchelson, F | 1 |
| Jaiswal, N; Lambrecht, G; Malik, KU; Mutschler, E; Tacke, R | 1 |
| Aikawa, T; Itabashi, S; Ohrui, T; Sasaki, H; Sekizawa, K; Takishima, T | 1 |
| Benedito, S; García-Sacristán, A; Hernández, M; Prieto, D; Rivera, L | 1 |
| Blaxall, HS; Cunningham, J; Gardier, RW; Killian, LN | 1 |
| Doods, H; Entzeroth, M; Mayer, N | 1 |
| Elzinga, CR; Roffel, AF; Zaagsma, J | 1 |
| Jackson, KN; Kachur, JF; Lowe, VC; Noronha-Blob, L; Sturm, BL | 1 |
| Duckles, SP | 1 |
| Brown, DA; Marrion, NV; Marsh, SJ; Smart, TG | 1 |
| Giachetti, A; Micheletti, R; Montagna, E | 1 |
46 other study(ies) available for afdx 116 and Muscle Contraction
| Article | Year |
|---|---|
Role of rho-kinase (ROCK) in tonic but not phasic contraction in the frog stomach smooth muscle.
Topics: Amides; Animals; Atropine; Carbachol; Gastric Mucosa; Muscle Contraction; Muscle, Smooth; Nifedipine; Organ Culture Techniques; Pirenzepine; Pyridines; Ranidae; rho-Associated Kinases | 2018 |
BK channel β1 subunits regulate airway contraction secondary to M2 muscarinic acetylcholine receptor mediated depolarization.
Topics: Animals; Calcium Channels, L-Type; Excitation Contraction Coupling; In Vitro Techniques; Indoles; Large-Conductance Calcium-Activated Potassium Channel beta Subunits; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pirenzepine; Potassium Channel Blockers; Receptor, Muscarinic M2; Respiratory Mechanics; Signal Transduction; Trachea | 2011 |
Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle.
Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Pyridines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; rho-Associated Kinases; Signal Transduction; Urinary Bladder | 2012 |
A role for M(2) and M(3) muscarinic receptors in the contraction of rat and human small airways.
Topics: Animals; Carbachol; Cholinergic Agonists; Humans; In Vitro Techniques; Lung; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Scopolamine Derivatives; Tiotropium Bromide | 2013 |
In vitro effects of bethanechol on equine gastrointestinal contractility and functional characterization of involved muscarinic receptor subtypes.
Topics: Animals; Area Under Curve; Bethanechol; Cecum; Dose-Response Relationship, Drug; Duodenum; Female; Gastrointestinal Motility; Horses; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pelvic Floor; Pirenzepine; Receptors, Muscarinic | 2005 |
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Diamines; Electric Stimulation; Muscle Contraction; Muscle Hypertonia; Muscle, Smooth; Parasympatholytics; Peptides; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2006 |
Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Emptying; Gastric Fundus; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Physostigmine; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Stomach | 2007 |
Paradoxical effect of salbutamol in a model of acute organophosphates intoxication in guinea pigs: role of substance P release.
Topics: Albuterol; Animals; Calcium; Cholinesterase Inhibitors; Colforsin; Diamines; Guinea Pigs; Lung; Male; Muscle Contraction; omega-Conotoxins; Parathion; Physostigmine; Pirenzepine; Plethysmography, Whole Body; Substance P; Tetrodotoxin; Tryptophan | 2007 |
In vitro effects of bethanechol on specimens of intestinal smooth muscle obtained from the duodenum and jejunum of healthy dairy cows.
Topics: Animals; Bethanechol; Cattle; Dairying; Dose-Response Relationship, Drug; Duodenum; Female; In Vitro Techniques; Jejunum; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Tropicamide | 2007 |
Muscarinic receptor subtypes mediating vasodilation and vasoconstriction in isolated, perfused simian coronary arteries.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Coronary Vessels; Endothelium, Vascular; Female; In Vitro Techniques; Macaca; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth, Vascular; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasoconstriction; Vasodilation | 1993 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
No evidence for a role of muscarinic M2 receptors in functional antagonism in bovine trachea.
Topics: Animals; Bronchoconstrictor Agents; Cattle; Dose-Response Relationship, Drug; Gallamine Triethiodide; Histamine; In Vitro Techniques; Isoproterenol; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1995 |
Prejunctional M1 and postjunctional M3 muscarinic receptors in the circular muscle of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Choline; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1995 |
Mode of antagonism of methoctramine, AF-DX 116 and hexahydrosiladifenidol in guinea-pig left atrium and ileum: comparison of Schild and resultant analysis.
Topics: Animals; Diamines; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Piperidines; Pirenzepine | 1995 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mulatta; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Quinuclidines | 1994 |
Pertussis toxin-sensitive muscarinic relaxation in the rat iris dilator muscle.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Diamines; Dose-Response Relationship, Drug; Furans; GTP-Binding Proteins; In Vitro Techniques; Iris; Male; Microinjections; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pertussis Toxin; Phentolamine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Virulence Factors, Bordetella | 1995 |
Role of G proteins and KCa channels in the muscarinic and beta-adrenergic regulation of airway smooth muscle.
Topics: Adenylate Cyclase Toxin; Animals; Calcium; Cholera Toxin; GTP-Binding Proteins; Guinea Pigs; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pertussis Toxin; Pirenzepine; Potassium Channel Blockers; Potassium Channels; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea; Virulence Factors, Bordetella | 1995 |
Pertussis toxin blocks M2 muscarinic receptor-mediated effects on contraction and cyclic AMP in the guinea pig ileum, but not M3-mediated contractions and phosphoinositide hydrolysis.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cyclic AMP; Guanosine Triphosphate; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction; Virulence Factors, Bordetella | 1994 |
Pharmacological characterization of muscarinic receptors mediating acetylcholine-induced contraction and relaxation in rabbit intrapulmonary arteries.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Heart Atria; Ileum; Lung; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Pirenzepine; Pulmonary Artery; Rabbits; Receptors, Muscarinic | 1994 |
Characterization of muscarinic receptors on guinea pig gallbladder smooth muscle.
Topics: Animals; Autoradiography; Carbachol; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tetrodotoxin | 1993 |
Functional role for the M2 muscarinic receptor in smooth muscle of guinea pig ileum.
Topics: Animals; Cyclic AMP; Diphenylacetic Acids; Guinea Pigs; Hydrolysis; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Second Messenger Systems | 1993 |
Functional characterization of muscarinic receptors in murine airways.
Topics: Administration, Inhalation; Airway Resistance; Animals; Atropine; Bronchi; Electric Stimulation; In Vitro Techniques; Isometric Contraction; Lung Compliance; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1993 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Furans; Humans; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Pirenzepine | 1995 |
Involvement of the M2 muscarinic receptor in contractions of the guinea pig trachea, guinea pig esophagus, and rat fundus.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Esophagus; Gastric Fundus; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pertussis Toxin; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serotonin; Trachea; Virulence Factors, Bordetella | 1996 |
Cardiopulmonary actions of muscarinic receptor subtypes in the newborn dog.
Topics: Airway Resistance; Analysis of Variance; Animals; Animals, Newborn; Bronchoconstriction; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pirenzepine; Respiratory Mechanics; Vagus Nerve | 1996 |
Contractile roles of the M2 and M3 muscarinic receptors in the guinea pig colon.
Topics: Animals; Colforsin; Colon; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Virulence Factors, Bordetella | 1998 |
Muscarinic M2 receptor-mediated contraction in the guinea pig Taenia caeci: possible involvement of protein kinase C.
Topics: Animals; Cecum; Colforsin; Diphenylacetic Acids; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Protein Kinase C; Receptor, Muscarinic M2; Receptors, Muscarinic; Second Messenger Systems | 1998 |
Muscarinic M3 receptor inactivation reveals a pertussis toxin-sensitive contractile response in the guinea pig colon: evidence for M2/M3 receptor interactions.
Topics: Animals; Colon; Diphenylacetic Acids; Guinea Pigs; Hydrolysis; In Vitro Techniques; Male; Models, Biological; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Virulence Factors, Bordetella | 1999 |
M(2) and M(4) receptor knockout mice: muscarinic receptor function in cardiac and smooth muscle in vitro.
Topics: Adenosine; Animals; Carbachol; Heart Rate; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic | 2000 |
Functional role of muscarinic M(2) receptors in alpha,beta-methylene ATP induced, neurogenic contractions in guinea-pig ileum.
Topics: Adenosine Triphosphate; Animals; Diphenylacetic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Tetrodotoxin; Virulence Factors, Bordetella | 2000 |
Mechanisms of acetylcholine-induced vasorelaxation in high K+-stimulated rabbit renal arteries.
Topics: Acetylcholine; Animals; Atropine; Calcium; Calcium Channel Blockers; Cations, Monovalent; Endothelium, Vascular; Gadolinium; Imidazoles; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Rabbits; Renal Artery; Tropicamide; Vasoconstriction; Vasodilation | 2001 |
Muscarinic receptor knockout mice: role of muscarinic acetylcholine receptors M(2), M(3), and M(4) in carbamylcholine-induced gallbladder contractility.
Topics: Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Cardiovascular Agents; Cholinesterase Inhibitors; Drug Interactions; Gallbladder; Indomethacin; Mice; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Neostigmine; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Muscarinic | 2002 |
A minority of muscarinic receptors mediate rabbit tracheal smooth muscle contraction.
Topics: Animals; Atropine; Female; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myocardium; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Radioligand Assay; Receptors, Muscarinic; Trachea | 1992 |
Pre- and postjunctional muscarinic receptors in canine bronchi.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds; Bronchi; Carbachol; Dogs; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
Selective inhibition of responses to carbachol and McN-A-343 in the rabbit vas deferens.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bis-Trimethylammonium Compounds; Carbachol; Cocaine; Electric Stimulation; In Vitro Techniques; Isoindoles; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pancuronium; Pirenzepine; Rabbits; Vas Deferens | 1990 |
Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Antihypertensive Agents; Aorta, Abdominal; Arecoline; Atropine; Diamines; Endothelium, Vascular; Hexamethonium; Hexamethonium Compounds; Indomethacin; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Norepinephrine; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic | 1991 |
Pre- and postjunctional muscarinic receptor subtypes in dog airways.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1991 |
Distribution and function of cholinergic receptors in the sheep detrusor muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Ganglia, Parasympathetic; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Piperidines; Pirenzepine; Receptors, Muscarinic; Sheep; Tetraisopropylpyrophosphamide; Urinary Bladder | 1991 |
Reserpine-induced post-receptor reduction in muscarinic-mediated airway smooth muscle contraction.
Topics: Animals; Binding, Competitive; Bronchi; Humans; Lung; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Organ Specificity; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Reserpine; Trachea | 1991 |
Cardioselectivity of AQ-RA 741, a novel tricyclic antimuscarinic drug.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Cats; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Muscarinic M3 receptors mediate contraction of human central and peripheral airway smooth muscle.
Topics: Bronchi; Humans; In Vitro Techniques; Ipratropium; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1990 |
Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle.
Topics: Animals; Cattle; In Vitro Techniques; Inositol Phosphates; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1990 |
In vitro and in vivo antimuscarinic effects of (-)cis 2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5 benzothiazepin-4-(5H)one HCl (BTM-1086) in guinea pig peripheral tissues.
Topics: Animals; Atropine; Calcium; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Structure-Activity Relationship; Thiazepines; Tumor Cells, Cultured; Urinary Bladder; Vas Deferens | 1990 |
Vascular muscarinic receptors: pharmacological characterization in the bovine coronary artery.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Calcimycin; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle Contraction; Muscle, Smooth, Vascular; Pirenzepine; Rabbits; Receptors, Muscarinic | 1988 |
Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype.
Topics: Animals; Calcium; Gallamine Triethiodide; Ganglia, Spinal; Ganglia, Sympathetic; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Piperidines; Pirenzepine; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1989 |
AF-DX 116, a cardioselective muscarinic antagonist.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Cats; Dimethylphenylpiperazinium Iodide; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastric Acid; Gastric Emptying; Guinea Pigs; Heart; Heart Rate; Male; Muscarine; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Pirenzepine; Rats; Receptors, Muscarinic | 1987 |