af-219 has been researched along with Neuralgia* in 1 studies
1 other study(ies) available for af-219 and Neuralgia
| Article | Year |
|---|---|
Electroacupuncture Reduces Ocular Surface Neuralgia in Dry-Eyed Guinea Pigs by Inhibiting the Trigeminal Ganglion and Spinal Trigeminal Nucleus Caudalis P2X
To observe the effects of electroacupuncture on ocular surface neuralgia and the P2X. A dry eye guinea pig model was established by subcutaneous injection of scopolamine hydrobromide. Guinea pigs were monitored for body weight, palpebral fissure height, number of blinks, corneal fluorescein staining score, phenol red thread test, and corneal mechanical perception threshold. Histopathological changes and mRNA expression of P2X. Dry-eyed guinea pigs showed pain-related manifestations and the expression of P2X. Electroacupuncture reduced ocular surface sensory neuralgia in dry-eyed guinea pigs, and the mechanism of action may be associated with the inhibition of the P2X Topics: Adenosine Triphosphate; Animals; Cornea; Dry Eye Syndromes; Electroacupuncture; Guinea Pigs; Neuralgia; Protein Kinase C; Signal Transduction; Trigeminal Ganglion; Trigeminal Nucleus, Spinal | 2023 |