adenosine monophosphate has been researched along with Disease Models, Animal in 143 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 26 (18.18) | 18.7374 |
1990's | 12 (8.39) | 18.2507 |
2000's | 24 (16.78) | 29.6817 |
2010's | 51 (35.66) | 24.3611 |
2020's | 30 (20.98) | 2.80 |
Authors | Studies |
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Benardeau, A; Benz, J; Gubler, M; Haap, W; Hebeisen, P; Huber, W; Joseph, C; Kitas, E; Kuhn, B; Mohr, P; Paehler, A; Ruf, A; Sanchez, RA; Schott, B; Tozzo, E; Wessel, HP | 1 |
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Bannister, R; Bavari, S; Cihlar, T; Donnelly, G; Garza, NL; Gomba, L; Iversen, PL; Kane, CD; Norris, S; Porter, DP; Steffens, J; Stuthman, KS; Van Tongeren, SA; Warren, TK; Weidner, JM; Wells, J; Zeng, X | 1 |
Allerton, C; Anderson, AS; Anson, BJ; Arenson, D; Aschenbrenner, L; Bakowski, MA; Beutler, N; Binder, J; Boras, B; Chatterjee, AK; Chen, E; Eng, H; Frieman, MB; García-Sastre, A; Hammond, H; Hammond, J; Haupt, RE; Hoffman, R; Jones, RM; Kadar, EP; Kania, R; Kimoto, E; Kirkpatrick, MG; Lanyon, L; Lendy, EK; Lillis, JR; Logue, J; Luthra, SA; Ma, C; Mason, SW; McGrath, ME; Mesecar, AD; Noell, S; O' Brien, MN; O'Connor, R; Obach, RS; Ogilvie, K; Owen, D; Pettersson, M; Reese, MR; Rogers, TF; Rosales, R; Rossulek, MI; Sathish, JG; Shirai, N; Steppan, C; Ticehurst, M; Updyke, LW; Wang, J; Weston, S; White, KM; Zhu, Y | 1 |
Bai, H; Gao, L; Jiao, G; Li, T; Liu, L; Ma, T; Song, X; Wang, X; Zhang, Z | 1 |
Babusis, D; Bosio, CM; Cihlar, T; de Wit, E; Feldmann, F; Haddock, E; Hanley, PW; Holbrook, MG; Lovaglio, J; Lye, DS; Mackman, RL; Okumura, A; Pérez-Pérez, L; Porter, DP; Saturday, G; Schwarz, B; Singh, M; Subramanian, R; Williamson, BN | 1 |
Sha, B; Shu, Q; Yan, X; Zhang, Y; Zhao, L | 1 |
Basovich, MB; Buvanendran, A; Das, V; Kroin, JS; McCarthy, RJ | 1 |
Mei, X; Wang, G; Yang, H; Zuo, W | 1 |
Guo, D; Huang, L; Ji, S; Jiang, Y; Ma, X; Wu, Y; Yu, L; Zhu, R | 1 |
Arbab, M; Aytan, D; Bezler, AK; Fakhari, M; Junger, WG; Kondo, Y; Ledderose, C; Slubowski, CJ; Sueyoshi, K; Sumi, Y | 1 |
Charles, CJ; Espiner, EA; Rademaker, MT; Richards, AM; Scott, NJA | 1 |
Gao, Y; Ge, W; Liu, J; Sun, Q; Xu, X; Yang, X; Yang, Y; Zhang, J; Zhao, Y | 1 |
Cho, JY; Kim, B; Kim, H; Kim, HS | 1 |
Cihlar, T; Cronin, J; de Wit, E; Feldmann, F; Feldmann, H; Jordan, R; Okumura, A; Scott, D; Thomas, T | 1 |
Maxmen, A | 1 |
Dong, L; Lu, Y; Wang, Q; Wei, T; Wu, M; Wu, Z; Yan, Q; Zhan, T; Zhang, W | 1 |
Agostini, ML; Baric, RS; Bluemling, GR; Brown, AJ; Chappell, JD; Denison, MR; Dinnon, KH; George, AS; Graham, RL; Harcourt, J; Hill, CS; Hughes, TM; Kolykhalov, AA; Leist, SR; Lu, X; Montgomery, SA; Natchus, MG; Painter, G; Pruijssers, AJ; Saindane, M; Schäfer, A; Sheahan, TP; Sims, AC; Stevens, LJ; Swanstrom, R; Tamin, A; Thornburg, NJ; Zhou, S | 1 |
Bannister, R; Bavari, S; Bearss, J; Blair, C; Cihlar, T; Donnelly, G; Garza, N; Gomba, L; Jordan, R; Lee, E; Moreau, A; Porter, DP; Steffens, J; Van Tongeren, S; Warren, TK; Weidner, JM; Wells, J; Wetzel, K | 1 |
Anzick, S; Barbian, K; Bosio, CM; Cihlar, T; de Wit, E; Feldmann, F; Hanley, PW; Leighton, I; Lovaglio, J; Martens, C; Meade-White, K; Munster, VJ; Okumura, A; Pérez-Pérez, L; Porter, DP; Saturday, G; Schulz, J; Schwarz, B; Scott, DP; van Doremalen, N; Williamson, BN; Yinda, CK | 1 |
Hua, Y; Liu, D; Qin, W; Wang, X; Wei, Q; Zhang, D | 1 |
Bu, Z; Ge, J; He, X; Hua, R; Liu, R; Shan, D; Shuai, L; Sun, Z; Wang, C; Wang, J; Wang, X; Wen, Z; Zhang, X; Zhong, G | 1 |
Christensen, MG; Hamilton, ADM; Hvas, AM; Johnsen, N; Praetorius, H; Rubak, P; Skals, M | 1 |
Dobrovolny, HM | 1 |
Campelj, DG; Goodman, CA; Hayes, A; Rybalka, E; Timpani, CA | 1 |
Kaplan, HJ; Ko, MK; Shao, H; Sun, D | 1 |
Cicka, D; Sukhatme, VP | 1 |
Cai, JP; Cao, J; Chan, CC; Chan, JF; Chu, H; Jin, DY; Ong, CP; Poon, VK; Tang, K; Yang, D; Ye, ZW; Yu, CY; Yuan, S; Yuen, KY; Zhang, AJ | 1 |
Goudarzi, I; Jafari, A; Rashtiani, S; Rohampour, K | 1 |
Alasadi, A; Augeri, D; Cao, B; Collantes, J; Guo, J; Jin, S; Su, X; Tan, V; Tao, H | 1 |
Abelson, DM; Agans, KN; Borisevich, V; Bornholdt, ZA; Bunyan, E; Campbell, LA; Cross, RW; Deer, DJ; Fenton, KA; Geisbert, JB; Geisbert, TW; Kim, DH; Porter, DP; Prasad, AN; Shestowsky, WS; Zeitlin, L | 1 |
Dong, Y; Ju, H; Kong, F; Li, Y; Yin, L; Zhang, H; Zhao, H; Zhao, S | 1 |
Chen, G; Guo, D; Hang, M; Jin, Q; Kang, Q; Liu, G; Liu, R; Luo, Q; Qu, K; Xu, L | 1 |
Chang, L; Ding, Z; Hu, L; Kunapuli, SP; Luo, X; Qi, Z; Wang, Y; Yan, H; Yan, Y; Ye, H; Zhai, L; Zhang, S; Zhang, Y | 1 |
Deppen, J; García, AJ; Levit, RD; Shin, EY; Strobel, F; Tirouvanziam, R; Wang, L; Xu, K; Zemskova, M | 1 |
Forbes, B; Keir, S; Lexmond, AJ; Page, CP; Terakosolphan, W | 1 |
Diachkova, N; Iatsyna, O; Kharkhota, M; Kostev, F | 1 |
Abshagen, K; Berg, CP; Courth, L; Dayoub, R; Ehmann, D; Klag, T; Mailänder-Sanchez, D; Malek, NP; Stange, EF; Thasler, WE; Thomas, M; Vollmar, B; Wehkamp, J; Weiss, TS; Zanger, UM | 1 |
Hughey, CC; Hunter, RW; Jessen, N; Lantier, L; Peggie, M; Sakamoto, K; Sicheri, F; Sundelin, EI; Wasserman, DH; Zeqiraj, E | 1 |
Ando, F; Arai, Y; Furusho, T; Isobe, K; Kikuchi, H; Maejima, Y; Mandai, S; Minamishima, YA; Mori, T; Nomura, N; Okado, T; Rai, T; Sasaki, E; Sohara, E; Takahashi, N; Uchida, S; Yamashita, T; Yoshizaki, Y | 1 |
Gao, J; Jiang, G; Xiong, D; Xiong, R; Yin, T; Yin, Z; Zhang, S; Zhang, X; Zhao, W | 1 |
Joolharzadeh, P; St Hilaire, C | 1 |
Coley, W; Duba, AS; Nagaraju, K; Rayavarapu, S; van der Meulen, JH | 1 |
Ding, B; Hou, Y; Li, J; Liu, Y; Long, M; Wang, L; Wu, G; Yang, Z; Yi, D | 1 |
Corder, G; Donahue, RR; Doolen, S; He, Y; Hu, X; Jutras, BL; McCarson, KE; Mogil, JS; Storm, DR; Taylor, BK; Wang, ZJ; Wieskopf, JS; Winter, MK | 1 |
Chiarugi, A; Coppi, E; Muzzi, M; Pugliese, AM | 1 |
Cui, L; Guo, W; Li, C; Li, Y; Liu, B; Lv, W; Pan, X; Wang, Y; Yan, S; Zhang, J | 1 |
Alarcón, M; Badimon, L; Caballero, J; Fuentes, E; Padró, T; Palomo, I; Pérez, P; Vilahur, G | 1 |
Chang, YS; Cho, YR; Hong, BY; Kim, HW; Kim, MY; Kim, TW; Kim, YS; Lim, JH; Park, CW | 1 |
Bao, Y; Chen, Y; Inoue, Y; Junger, WG; Li, X; Sumi, Y; Tanaka, H; Woehrle, T; Yao, Y | 1 |
Hou, L; Jia, D; Jiang, Y; Li, X; Lu, S; Pan, X; Sun, Y; Wang, X; Wang, Y; Yu, W; Zhang, A; Zhang, J | 1 |
El Ghalbzouri, A; Haisma, EM; Nibbering, PH; Out-Luiting, JJ; van Drongelen, V | 1 |
Aksentijević, D; Brookes, PS; Chouchani, ET; Costa, ASH; Dare, AJ; Davidson, SM; Duchen, MR; Eaton, S; Eyassu, F; Frezza, C; Gaude, E; Hartley, RC; Hu, CH; James, AM; Krieg, T; Logan, A; Murphy, MP; Nadtochiy, SM; Ord, ENJ; Pell, VR; Robb, EL; Robinson, AJ; Rogatti, S; Saeb-Parsy, K; Shattock, MJ; Shirley, R; Smith, AC; Sundier, SY; Work, LM | 1 |
Alexeyev, M; Cohen, MV; Cui, L; Downey, JM; Gillespie, MN; Kuck, J; Ruchko, MV; White, J; Wilson, GL; Yang, XM | 1 |
Deng, X; Gan, N; He, F; Kong, H; Peng, J; Wu, L; Yang, P; Yin, F | 1 |
Chen, JF; Hou, X; Liang, X; Zheng, J | 1 |
Dai, J; Miao, YF; Qiu, YM; Tao, ZY; Wu, H; Yang, SF; Zhang, XH | 1 |
Basilico, P; Benarafa, C; Collins, P; Cremona, TP; Dai, C; Moser, B; Wolf, M | 1 |
Cambon, K; Déglon, N; Dolores Sequedo, M; Farina, F; Millán, JM; Neri, C; Parker, AJ; Vázquez-Manrique, RP; Weiss, A | 1 |
Frelinger, AL; Gremmel, T; Michelson, AD; Przyklenk, K; Undyala, VV; Wider, J; Wright, GE; Yanachkov, IB; Yanachkova, MI | 1 |
Battastini, AM; Bergamin, LS; de Oliveira, CP; Figueiró, F; Guterres, SS; Jandrey, EH; Mendes, FB; Moritz, CE; Pettenuzzo, LF; Pohlmann, AR; Rockenbach, L; Sévigny, J | 1 |
Leech, JM; McLoughlin, RM; Mills, KH; Mulcahy, ME; Renauld, JC | 1 |
Agu, RU; Kolathuru, SS; Yeung, PK | 1 |
Abushik, P; Fayuk, D; Giniatullin, R; Giniatullina, R; Guerrero-Toro, C; Ishchenko, Y; Kilinc, E; Koroleva, K; Yegutkin, GG | 1 |
Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG | 1 |
Bang, E; Jang, HJ; Kim, KH; Kim, Y; Lee, IS; Lee, JH; Na, YC; Park, J | 1 |
Kong, Y; Sun, Q; Xu, X; Yang, X; Zhan, Y; Zhang, J | 1 |
Araldi, D; Ferrari, LF; Levine, JD | 1 |
Bottari, NB; Da Silva, AS; de Sá, MF; do Carmo, GM; Doleski, PH; Grando, TH; Gressler, LT; Henker, LC; Leal, DB; Mendes, RE; Monteiro, SG | 1 |
Hofbauer, KG; Lecourt, AC; Peter, JC | 1 |
Chen, J; Ji, X; Luo, Y; Nemoto, EM; Wang, S; Zhang, F | 1 |
Bjelobaba, I; Lavrnja, I; Mostarica-Stojkovic, M; Nedeljkovic, N; Pekovic, S; Stojiljkovic, M; Stosic-Grujicic, S | 1 |
Dang, Q; Dare, J; Erion, MD; Gibson, T; Kasibhatla, SR; Liu, Y; Potter, SC; Reddy, KR; Scarlato, GR; Taplin, F; van Poelje, PD; Xiao, W | 1 |
Higaki, S; Shimomura, Y; Watanabe, K | 1 |
Inoue, K; Kiyama, H; Maeda, M; Tozaki-Saitoh, H; Tsuda, M | 1 |
Chintala, M; Kurowski, S; Li, Q; Strony, J; Yang, B | 1 |
Cowan, PJ; Crikis, S; d'Apice, AJ; Dwyer, KM; Lu, B; Rajakumar, SV; Robson, SC | 1 |
Bordel, V; Bruckner, B; Ghodsizad, A; Gregoric, I; Kallenbach, K; Karck, M; Kögler, G; Niehaus, M; Ruhparwar, A; Ungerer, MN | 1 |
Ding, Z; Du, H; Fan, Z; Gross, PL; Hu, L; Kunapuli, SP; Ni, R; Wei, X; Ye, J; Yin, K; Zhang, S; Zhang, X; Zhang, Y | 1 |
Cho, WJ; Hong, S; Kang, HJ; Kim, EJ; Kim, SG; Koo, SH; Lee, MH; Lee, MO; Na, TY; Park, HG; Park, J; Son, HY; Yoon, YS | 1 |
Bansal, R; Jackson, EK; Jackson, TC; Kochanek, PM; Okonkwo, DO; Puccio, AM; Verrier, JD | 1 |
Groves, JT; Karck, M; Loganathan, S; Merkely, B; Radovits, T; Szabó, C; Szabó, G | 1 |
Ding, Z; Hu, L; Kunapuli, SP; Li, Y; Ye, J; Zhang, S; Zhang, SH; Zhang, Y | 1 |
Akhtar, S; Choudhry, MA; Li, X; Rendon, JL | 1 |
Carneiro, M; Humphries, RG; Klein, A; Lincoff, AM; Murray, D; Penn, MS; Tarakji, K; Thomas, JD; Topol, EJ; Turner, J; Wang, K; Zhou, X; Zhou, Z | 1 |
Cazenave, JP; Freund, M; Gachet, C; Leon, C; Ravanat, C | 1 |
Axmann, S; Biberthaler, P; Enders, G; Khandoga, A; Krombach, F; Luchting, B; Minor, T; Nilsson, U | 1 |
Cosi, C; Fluit, P; Gallo-Hendrikx, E; Marien, MR; Martel, JC; Mount, HT; Wu, Y | 1 |
Jing, BW; Lou, YH; Yang, XY; Zhu, YY | 1 |
Carrier, M; DeMaria, RG; Denault, A; Desjardins, F; Fortier, S; Lamarche, Y; Malo, O; Perrault, LP | 1 |
Carling, D; Davies, JK; DeMayo, FJ; Gollob, MH; Khoury, DS; Marian, AJ; Rajawat, YS; Rami, TG; Roberts, R; Sidhu, JS; Taffet, GE; Wang, Z; Weilbacher, D; Yuan, R | 1 |
Feijge, MA; Giesen, PL; Heemskerk, JW; Jerling, JC; Kloots, W; Kuijpers, MJ; Nieuwenhuys, CM; oude Egbrink, MG | 1 |
Asai, T; Belov, D; Naka, Y; Okada, M; Pinsky, DJ; Sakaguchi, T; Schmidt, AM | 1 |
Barreto-Chaves, ML; Bonan, CD; Bruno, AN; Freitas Sarkis, JJ; Pochmann, D; Ricachenevsky, FK | 1 |
Barman, SA; Meadows, ML; White, RE; Zhu, S | 1 |
Bagchi, D; Bagchi, M; Juhasz, B; Maulik, N; Penumathsa, S; Shara, MA; Thatte, HS; Thirunavukkarasu, M; Yasmin, T; Zhan, L | 1 |
Cronin, C; Gongora Nieto, M; Harrison, D; Jacobson, KA; Joshi, BV; Liang, BT; Shen, JB; Sonin, D | 1 |
Belardinelli, L; Fan, M; Mustafa, SJ; Nadeem, A; Zeng, D; Zhong, H | 1 |
Chan, TO; Feldman, AM; Funakoshi, H; Good, JC; Herrmann, DE; Higuchi, Y; Jackson, EK; Koch, WJ; Lee, LL; Tang, Z; Zacharia, LC; Zhang, J | 1 |
Gu, YT; Xue, YX; Zhang, H | 1 |
Eckle, T; Eltzschig, HK; Faigle, M; Grenz, A; Hart, ML; Köhler, D; Laucher, S; Mittelbronn, M; Müller, CE; Robson, SC | 1 |
Denborough, MA; Marjanen, LA | 1 |
Bresler, VM; Chusova, GG; Ostapenko, IA; Rebane, EN | 1 |
Cowley, RA; Kahng, MW; Trifillis, AL; Trump, BF | 1 |
Hirano, T; Manabe, T | 1 |
He, YY; Hsu, CY; Lin, TA; Lin, TN; Sun, GY; Zhang, JP | 1 |
Abiko, Y; Ichihara, K; Kamigaki, M | 1 |
Corsi, M; Ferrero, ME; Gaja, G; Parise, M | 1 |
Brown, CG; Cody, RJ; Griffith, R; Hoekstra, JW; Kelley, R; Lewis, D; Scheatzle, M | 1 |
Pancza, D; Ravingerová, T; Seboková, J; Slezák, J; Styk, J; Tribulová, N; Volkovová, K; Ziegelhoffer, A | 1 |
Bernocchi, P; Ceconi, C; Curello, S; Ferrari, R; Pasini, E; Pedersini, P | 1 |
Alvarez, J; Arias-Diaz, J; Balibrea, JL; del Barrio, R; Garcia-Carreras, C; Gomez, M; Gonzalez, P | 1 |
Araki, J; Hirakawa, M; Hosogi, S; Matsubara, H; Mikane, T; Mohri, S; Ohe, T; Suga, H; Suzuki, S; Syuu, Y | 1 |
Mies, G; Oláh, L; Paschen, W | 1 |
Driscoll, EM; Gonzales, ML; Huang, J; Lucchesi, BR; Park, AM | 1 |
Al-Awadi, FM; Khan, I | 1 |
Cherchenko, AP; Todor, IM | 1 |
Tygstrup, N | 1 |
Becker, B; Kass, MA; Palmberg, P | 1 |
Glasgow, LA; Kern, ER; Overall, JC; Richards, JT | 1 |
Dean, BM; Perrett, D; Sensi, M | 1 |
Falcon, MG; Jones, BR | 1 |
Cunningham, SK; Keaveny, TV | 1 |
Kamiyama, Y; Nambu, H; Ohshita, M; Takeda, H; Yamaoka, Y | 1 |
De Jong, JW; Stam, H | 1 |
Brachfeld, N; Horner, H; Kligfield, P | 1 |
Hughes, HC; Liedtke, AJ; Neely, JR | 1 |
Hossmann, KA; Kleihues, P; Kobayashi, K; Pegg, AE; Zimmermann, V | 1 |
De Jong, JW; Goldstein, S | 1 |
Geppert, E; Heugel, E; Isselhard, W; Lauterjung, KL; Menge, M; Vogel, W; Witte, J | 1 |
Liedtke, AJ | 1 |
Andiné, P; Hagberg, H; Lehmann, A; Thordstein, M | 1 |
Canada, AT; Martel, D; Stein, K; Watkins, WD | 1 |
Chumakov, VN; Starchik, TG | 1 |
Bianco, R; Einzig, S; Foker, J; Noren, G; St Cyr, J; Staley, N; Wang, TC | 1 |
Holmin, T; Siesjö, BK; Vang, J | 1 |
Havivi, E; Tal, R | 1 |
Morgan, HE; Neely, JR; Rovetto, MJ; Whitmer, JT | 1 |
Plum, F; Salford, LG; Siesjö, BK | 1 |
Kloppick, E; Krause, EG; Schneider, M; Vogel, I; Wollenberger, A | 1 |
Keiding, N; Keiding, S; Tystrup, N | 1 |
Ljunggren, B; Schutz, H; Siesjö, BK | 1 |
Ljunggren, B; Ratcheson, RA; Siesjö, BK | 1 |
3 review(s) available for adenosine monophosphate and Disease Models, Animal
Article | Year |
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CD73 (Cluster of Differentiation 73) and the Differences Between Mice and Humans.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Clinical Trials as Topic; Disease Models, Animal; GPI-Linked Proteins; Humans; Inflammation; Joint Diseases; Mice, Knockout; Molecular Targeted Therapy; Neoplasms; Phenotype; Species Specificity; Thrombophilia; Tunica Media; Vascular Calcification; Vascular Diseases; Vascular Remodeling | 2019 |
Suppression of herpes simplex virus 1 reactivation in a mouse eye model by cyclooxygenase inhibitor, heat shock protein inhibitor, and adenosine monophosphate.
Topics: Adenosine Monophosphate; Animals; Antiviral Agents; Benzoquinones; Cyclooxygenase Inhibitors; Disease Models, Animal; Herpesvirus 1, Human; HSP90 Heat-Shock Proteins; Keratitis, Herpetic; Lactams, Macrocyclic; Mice; Virus Activation | 2010 |
Aspects of hepatic hypoxia: observations on the isolated, perfused pig liver.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Galactose; Hypoxia; Liver; Liver Diseases; Oxygen Consumption; Perfusion; Phosphotransferases; Swine | 1975 |
1 trial(s) available for adenosine monophosphate and Disease Models, Animal
Article | Year |
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Analgesic Effectiveness and Dorsal Root Ganglia Protein Modulation of a Peripheral Adenosine Monophosphate Kinase Alpha Activator (O304) Following Lumbar Disk Puncture in the Mouse.
Topics: Adenosine Monophosphate; AMP-Activated Protein Kinases; Analgesics; Animals; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Male; Mammals; Mice; Mice, Inbred C57BL; Rats; Spinal Puncture | 2022 |
139 other study(ies) available for adenosine monophosphate and Disease Models, Animal
Article | Year |
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Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of type-2 diabetes.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructose-Bisphosphatase; High-Throughput Screening Assays; Humans; Hypoglycemic Agents; Mice; Structure-Activity Relationship; Sulfonylurea Compounds; Thiazoles | 2010 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus.
Topics: Adenosine Monophosphate; Administration, Intravenous; Aerosols; Alanine; Animals; Antiviral Agents; Disease Models, Animal; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Kaplan-Meier Estimate; Liver; Lung; Lymph Nodes; Macaca mulatta; Male; Random Allocation; Systemic Inflammatory Response Syndrome; Viral Load; Viremia | 2021 |
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19.
Topics: Adenosine Monophosphate; Alanine; Animals; Chlorocebus aethiops; Coronavirus 229E, Human; Coronavirus 3C Proteases; Coronavirus Protease Inhibitors; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Drug Design; Drug Synergism; Drug Therapy, Combination; HeLa Cells; Humans; Indoles; Infusions, Intravenous; Leucine; Mice; Pyrrolidinones; SARS-CoV-2; Severe acute respiratory syndrome-related coronavirus; Vero Cells | 2021 |
CF101 alleviates OA progression and inhibits the inflammatory process via the AMP/ATP/AMPK/mTOR axis.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Cartilage, Articular; Chondrocytes; Collagen Type II; Disease Models, Animal; Inflammation; Osteoarthritis; Rats; TOR Serine-Threonine Kinases | 2022 |
Subcutaneous remdesivir administration prevents interstitial pneumonia in rhesus macaques inoculated with SARS-CoV-2.
Topics: Adenosine Monophosphate; Administration, Cutaneous; Alanine; Animals; Antiviral Agents; COVID-19 Drug Treatment; Disease Models, Animal; Female; Lung; Lung Diseases, Interstitial; Macaca mulatta; Male; SARS-CoV-2; Viral Load; Virus Replication | 2022 |
The Pivotal Mediating Role of Adenosine Monophosphate-Activated Protein Kinase (AMPK) in Liver Tight Junctions and Liver Regeneration of a Partial-Hepatectomy Mouse Model.
Topics: Adenosine Monophosphate; AMP-Activated Protein Kinases; Animals; Bilirubin; Claudin-3; Disease Models, Animal; Focal Nodular Hyperplasia; Hepatectomy; Liver Regeneration; Mice; Occludin; Tight Junction Proteins; Tight Junctions; Zonula Occludens-1 Protein | 2022 |
Antidepressant-like effect of acute dose of Naringin involves suppression of NR1 and activation of protein kinase A/cyclic adenosine monophosphate response element-binding protein/brain-derived neurotrophic factor signaling in hippocampus.
Topics: Adenosine Monophosphate; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclic AMP-Dependent Protein Kinases; Depression; Disease Models, Animal; Hippocampus; Mice; Receptors, N-Methyl-D-Aspartate; Response Elements; Swimming | 2023 |
Novel Phenylethanoid Glycosides Improve Hippocampal Synaptic Plasticity via the Cyclic Adenosine Monophosphate-CREB-Brain-Derived Neurotrophic Growth Factor Pathway in APP/PS1 Transgenic Mice.
Topics: Adenosine Monophosphate; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Hippocampus; Maze Learning; Mice; Mice, Transgenic; Nerve Growth Factor; Neuronal Plasticity | 2023 |
Frontline Science: Escherichia coli use LPS as decoy to impair neutrophil chemotaxis and defeat antimicrobial host defense.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Biomarkers; Chemotaxis, Leukocyte; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Host-Pathogen Interactions; Humans; Intracellular Space; Lipopolysaccharides; Mice; Mitochondria; Neutrophil Activation; Neutrophils; Peritonitis | 2019 |
Hemodynamic, Hormonal, and Renal Actions of Phosphodiesterase-9 Inhibition in Experimental Heart Failure.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Monophosphate; Aldosterone; Animals; Atrial Natriuretic Factor; Atrial Pressure; Blood Pressure; Cardiac Output; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Guanosine Monophosphate; Heart Failure; Phosphodiesterase Inhibitors; Renin; Sheep; Sodium; Urine; Vascular Resistance; Vasopressins | 2019 |
Adenosine accumulation causes metabolic disorders in testes and associates with lower testosterone level in obese mice.
Topics: Adenosine; Adenosine Monophosphate; Animals; Disease Models, Animal; Down-Regulation; Gene Expression; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Testis; Testosterone; TOR Serine-Threonine Kinases; Up-Regulation | 2020 |
Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer's disease animal model.
Topics: Adenosine Monophosphate; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cells, Cultured; Dendritic Spines; Disease Models, Animal; Disease Progression; Female; Hippocampus; Lysophosphatidylcholines; Lysophospholipids; Male; Metabolomics; Mice, Transgenic; Mutation, Missense; Neurons; Niacinamide; Peptide Fragments; Point Mutation; Presenilin-1 | 2020 |
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Disease Models, Animal; Lung; Macaca mulatta; Male; Middle East Respiratory Syndrome Coronavirus; Pandemics; Pneumonia, Viral; Post-Exposure Prophylaxis; SARS-CoV-2; Viral Load; Virus Replication | 2020 |
More than 80 clinical trials launch to test coronavirus treatments.
Topics: Adenosine Monophosphate; Alanine; Animals; Anti-HIV Agents; Betacoronavirus; China; Chloroquine; Clinical Trials as Topic; Coronavirus Infections; COVID-19; COVID-19 Serotherapy; Dioxanes; Disease Models, Animal; Drug Combinations; Humans; Immunization, Passive; Lopinavir; Medicine, Chinese Traditional; Monosaccharides; Pandemics; Pneumonia, Viral; Registries; Ritonavir; SARS-CoV-2; Severe Acute Respiratory Syndrome; Stem Cell Transplantation; Steroids; Time Factors; Treatment Outcome; World Health Organization | 2020 |
Cangrelor alleviates bleomycin-induced pulmonary fibrosis by inhibiting platelet activation in mice.
Topics: Adenosine Monophosphate; Animals; Bleomycin; CD40 Antigens; Cytokines; Disease Models, Animal; Inflammation Mediators; Lung; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Neutrophils; Platelet Activation; Platelet Aggregation Inhibitors; Pulmonary Fibrosis | 2020 |
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Topics: Adenosine Monophosphate; Alanine; Animals; Antibiotic Prophylaxis; Antiviral Agents; Betacoronavirus; Cell Line; Coronavirus Infections; COVID-19; Cytidine; Disease Models, Animal; Drug Resistance, Viral; Humans; Hydroxylamines; Lung; Mice; Mice, Inbred C57BL; Middle East Respiratory Syndrome Coronavirus; Models, Molecular; Mutation; Pandemics; Pneumonia, Viral; Primary Cell Culture; Random Allocation; Respiratory System; Ribonucleosides; RNA-Dependent RNA Polymerase; RNA, Viral; SARS-CoV-2; Virus Replication | 2020 |
Remdesivir (GS-5734) Is Efficacious in Cynomolgus Macaques Infected With Marburg Virus.
Topics: Adenosine Monophosphate; Alanine; Animals; Antimetabolites; Antiviral Agents; Disease Models, Animal; Female; Kaplan-Meier Estimate; Macaca fascicularis; Male; Marburg Virus Disease; Marburgvirus; Monkey Diseases; RNA, Viral | 2020 |
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2.
Topics: Adenosine Monophosphate; Alanine; Animals; Betacoronavirus; Bronchoalveolar Lavage Fluid; Coronavirus Infections; COVID-19; Disease Models, Animal; Disease Progression; DNA Mutational Analysis; Drug Resistance, Viral; Female; Lung; Macaca mulatta; Male; Pandemics; Pneumonia, Viral; SARS-CoV-2; Secondary Prevention; Time Factors; Viral Load; Virus Replication; Virus Shedding | 2020 |
Extracellular AMP Suppresses Endotoxemia-Induced Inflammation by Alleviating Neutrophil Activation.
Topics: Adenosine Monophosphate; Animals; Apoptosis; Cell Adhesion; Disease Models, Animal; Endotoxemia; Extracellular Space; Humans; Immunophenotyping; Lipopolysaccharides; Male; Mice; Neutrophil Activation; Neutrophil Infiltration; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Proteomics; Reactive Oxygen Species; Receptors, Purinergic P1; Severity of Illness Index; Signal Transduction | 2020 |
Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice.
Topics: Adaptation, Physiological; Adenosine Monophosphate; Administration, Intranasal; Alanine; Animals; Betacoronavirus; Chlorocebus aethiops; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Female; Host Specificity; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mutation, Missense; Nasal Mucosa; Pandemics; Pneumonia, Viral; RNA, Viral; SARS-CoV-2; Turbinates; Vero Cells; Viral Load; Virus Replication | 2020 |
Prevention of P2 Receptor-Dependent Thrombocyte Activation by Pore-Forming Bacterial Toxins Improves Outcome in A Murine Model of Urosepsis.
Topics: Adenosine Monophosphate; Animals; Bacterial Toxins; Blood Platelets; Deoxyadenine Nucleotides; Disease Models, Animal; Escherichia coli Proteins; Hemolysin Proteins; Humans; Male; Mice, Inbred BALB C; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Sepsis; Treatment Outcome; Urinary Tract Infections; Uropathogenic Escherichia coli | 2020 |
Quantifying the effect of remdesivir in rhesus macaques infected with SARS-CoV-2.
Topics: Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Disease Models, Animal; Drug Administration Schedule; Humans; Inflammation; Macaca mulatta; Models, Statistical; Pandemics; Pneumonia, Viral; SARS-CoV-2; Viral Load; Virus Replication | 2020 |
Adenylosuccinic acid: a novel inducer of the cytoprotectant Nrf2 with efficacy in Duchenne muscular dystrophy.
Topics: Adenosine Monophosphate; Animals; Disease Models, Animal; Humans; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NF-E2-Related Factor 2 | 2021 |
CD73
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Autoimmune Diseases; Cell Communication; Cells, Cultured; Coculture Techniques; Cytokines; Dendritic Cells; Disease Models, Animal; Female; Genes, T-Cell Receptor delta; GPI-Linked Proteins; Lipopolysaccharides; Lymphocyte Activation; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; Th17 Cells; Uvea; Uveitis | 2020 |
Available drugs and supplements for rapid deployment for treatment of COVID-19.
Topics: Adenosine Monophosphate; Alanine; Animals; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Drug Repositioning; Flavonoids; Humans; Mice; Nitro Compounds; Pharmaceutical Preparations; SARS-CoV-2; Small Molecule Libraries; Teicoplanin; Thiazoles | 2021 |
Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection.
Topics: Adenosine Monophosphate; Alanine; Animals; Antibodies, Viral; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Macrophages; Male; Mesocricetus; Methylprednisolone; Respiratory System; RNA, Viral; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Viral Load; Virus Replication | 2021 |
Adenosine monophosphate activated protein kinase (AMPK) is essential for the memory improving effect of adiponectin.
Topics: Adenosine Monophosphate; Adiponectin; Alzheimer Disease; AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Male; Memory; Memory Disorders; Rats, Wistar; Signal Transduction | 2021 |
Mitochondrial uncoupler MB1-47 is efficacious in treating hepatic metastasis of pancreatic cancer in murine tumor transplantation models.
Topics: Adenocarcinoma; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Disease Models, Animal; Glucose; Glycolysis; Heterografts; Humans; Liver Neoplasms; Mice; Mitochondria; Pyruvic Acid | 2021 |
Combination therapy protects macaques against advanced Marburg virus disease.
Topics: Adenosine Monophosphate; Alanine; Animals; Antibodies, Monoclonal; Antibodies, Viral; Disease Models, Animal; Drug Therapy, Combination; Macaca mulatta; Marburg Virus Disease; Marburgvirus; Viral Load | 2021 |
Remdesivir Alleviates Acute Kidney Injury by Inhibiting the Activation of NLRP3 Inflammasome.
Topics: Acute Kidney Injury; Adenosine Monophosphate; Alanine; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Disease Models, Animal; Humans; Immunomodulation; Inflammasomes; Inflammation Mediators; Macrophages, Peritoneal; Male; Mice; Mitogen-Activated Protein Kinases; Models, Biological; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction | 2021 |
Cangrelor ameliorates CLP-induced pulmonary injury in sepsis by inhibiting GPR17.
Topics: Acute Lung Injury; Adenosine Monophosphate; Animals; Cecum; Disease Models, Animal; Ligation; Mice; Mice, Inbred C57BL; Punctures; Purinergic P2Y Receptor Antagonists; Sepsis | 2021 |
Platelets Express Activated P2Y
Topics: Adenosine Monophosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Cell Line; Chlorides; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Inverse Agonism; Ferric Compounds; Fibrinolytic Agents; Humans; Male; Microfilament Proteins; NF-kappa B; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Purinergic P2Y12; Thrombosis | 2017 |
Adenosine Production by Biomaterial-Supported Mesenchymal Stromal Cells Reduces the Innate Inflammatory Response in Myocardial Ischemia/Reperfusion Injury.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Enzyme Inhibitors; GPI-Linked Proteins; Humans; Hydrogen Peroxide; Immunity, Innate; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Rats, Sprague-Dawley; Recovery of Function; Stem Cell Niche; Tissue Scaffolds | 2018 |
A novel method for studying airway hyperresponsiveness in allergic guinea pigs in vivo using the PreciseInhale system for delivery of dry powder aerosols.
Topics: Adenosine; Adenosine Monophosphate; Aerosols; Animals; Bronchoconstriction; Disease Models, Animal; Guinea Pigs; Lung; Male; Nebulizers and Vaporizers; Particle Size; Powders; Purinergic P1 Receptor Agonists; Respiratory Hypersensitivity | 2018 |
ENERGY PROFILE OF RATS WITH OVERACTIVE BLADDER SYNDROME PHARMACOLOGICALLY CORRECTED WITH QUERCETIN.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Administration, Oral; Animals; Antioxidants; Chromatography, High Pressure Liquid; Disease Models, Animal; Erythrocytes; Female; Male; Quercetin; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder, Overactive | 2018 |
β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids
Topics: Adenosine Monophosphate; Animals; beta-Defensins; Bile Acids and Salts; Bilirubin; Cholestasis; Constitutive Androstane Receptor; Disease Models, Animal; Gene Expression; Hepatocytes; Humans; Liver; Mice; Receptors, Cytoplasmic and Nuclear | 2018 |
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase.
Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; Animals; Base Sequence; Chickens; Disease Models, Animal; Fructose-Bisphosphatase; Glucose; Glucose Intolerance; Homeostasis; Humans; Hypoglycemia; Liver; Metformin; Mice, Inbred C57BL; Mutation; Obesity; Prodrugs; Ribonucleotides | 2018 |
Failure to sense energy depletion may be a novel therapeutic target in chronic kidney disease.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Diet, Protein-Restricted; Disease Models, Animal; Energy Metabolism; Fibrosis; Humans; Kidney; Male; Metabolomics; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Myocardium; Pyrones; Renal Insufficiency, Chronic; Signal Transduction; Thiophenes | 2019 |
The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN).
Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Diet, High-Fat; Diethylnitrosamine; Disease Models, Animal; Fatty Liver; Interleukin-6; Lipid Metabolism; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Ribonucleotides; STAT3 Transcription Factor; Triglycerides | 2018 |
Daily supplementation of D-ribose shows no therapeutic benefits in the MHC-I transgenic mouse model of inflammatory myositis.
Topics: Adenosine Monophosphate; AMP Deaminase; Animals; Behavior, Animal; Body Weight; Dietary Supplements; Disease Models, Animal; Female; Histocompatibility Antigens Class I; Male; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Muscle Contraction; Muscle, Skeletal; Myositis; Ribose | 2013 |
Dietary N-acetylcysteine supplementation alleviates liver injury in lipopolysaccharide-challenged piglets.
Topics: Acetylcysteine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cytokines; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Female; HSP70 Heat-Shock Proteins; Inflammation Mediators; Lipopolysaccharides; Liver; NF-kappa B; Random Allocation; Swine | 2014 |
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Animal; Freund's Adjuvant; Hyperalgesia; Isoflurane; Male; Mice; Naltrexone; Nociceptive Pain; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome | 2013 |
Anticonvulsant effect of AMP by direct activation of adenosine A1 receptor.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Monophosphate; Animals; Anticonvulsants; CA1 Region, Hippocampal; Disease Models, Animal; Epilepsy; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Organ Culture Techniques; Receptor, Adenosine A1; Xanthines | 2013 |
Hypothermia induced by adenosine 5'-monophosphate attenuates injury in an L-arginine-induced acute pancreatitis rat model.
Topics: Acute Disease; Adenosine Monophosphate; Amylases; Animals; Arginine; Disease Models, Animal; Hypothermia, Induced; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; NF-kappa B; Pancreatitis; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2014 |
Protective mechanisms of adenosine 5'-monophosphate in platelet activation and thrombus formation.
Topics: Adenosine A2 Receptor Agonists; Adenosine Monophosphate; Animals; Blood Platelets; CD40 Ligand; Cells, Cultured; Crotalid Venoms; Cyclic Nucleotide Phosphodiesterases, Type 3; Disease Models, Animal; Humans; Lasers; Lectins, C-Type; Mesenteric Veins; Mice; Molecular Targeted Therapy; P-Selectin; Peptide Fragments; Photochemical Processes; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptor, Adenosine A2A; Rose Bengal; Stereoisomerism; Thrombosis; Triazines; Triazoles | 2014 |
Therapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Monophosphate; AMP-Activated Protein Kinases; Animals; Blood Glucose; Body Weight; Cell Survival; Deoxyguanosine; Diabetic Neuropathies; Disease Models, Animal; Endothelial Cells; Fenofibrate; Fibrosis; Glycated Hemoglobin; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lipids; Mice; Neural Conduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Platelet Endothelial Cell Adhesion Molecule-1; PPAR alpha; Receptors, Vascular Endothelial Growth Factor; Schwann Cells; Sciatic Nerve; Sciatic Neuropathy; Transcription Factors; Transforming Growth Factor beta1 | 2014 |
Plasma ATP is required for neutrophil activation in a mouse sepsis model.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Male; Mice, Inbred C57BL; Neutrophil Activation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Sepsis; Suramin | 2014 |
Adenosine 5'-monophosphate-induced hypothermia inhibits the activation of ERK1/2, JNK, p38 and NF-κB in endotoxemic rats.
Topics: Adenosine Monophosphate; Animals; C-Reactive Protein; Chemokine CCL2; Disease Models, Animal; Endotoxemia; Enzyme Activation; Humans; Hypothermia, Induced; Lipopolysaccharide Receptors; Lipopolysaccharides; MAP Kinase Signaling System; NF-kappa B; Rats; Rats, Wistar; Toll-Like Receptor 4 | 2014 |
Reduced filaggrin expression is accompanied by increased Staphylococcus aureus colonization of epidermal skin models.
Topics: Adenosine Monophosphate; Animals; Cell Line; Dermatitis, Atopic; Disease Models, Animal; Epidermis; Filaggrin Proteins; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Humans; Interleukin-8; Interleukins; Intermediate Filament Proteins; Lipids; Staphylococcal Infections; Staphylococcus aureus | 2014 |
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Topics: Adenosine Monophosphate; Animals; Aspartic Acid; Citric Acid Cycle; Disease Models, Animal; Electron Transport; Electron Transport Complex I; Fumarates; Ischemia; Malates; Male; Metabolomics; Mice; Mitochondria; Myocardial Infarction; Myocardium; Myocytes, Cardiac; NAD; Reactive Oxygen Species; Reperfusion Injury; Stroke; Succinate Dehydrogenase; Succinic Acid | 2014 |
Mitochondrially targeted Endonuclease III has a powerful anti-infarct effect in an in vivo rat model of myocardial ischemia/reperfusion.
Topics: Adenosine Monophosphate; Animals; Deoxyribonuclease I; Disease Models, Animal; Endodeoxyribonucleases; Hemodynamics; Male; Mitochondria; Myocardial Infarction; Myocardial Reperfusion Injury; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins | 2015 |
The role of ubiquitin/Nedd4-2 in the pathogenesis of mesial temporal lobe epilepsy.
Topics: Adenosine Monophosphate; Analysis of Variance; Animals; Animals, Newborn; Antimanic Agents; Cells, Cultured; Cysteine Proteinase Inhibitors; Disease Models, Animal; Endosomal Sorting Complexes Required for Transport; Epilepsy, Temporal Lobe; Female; Gene Expression Regulation; Hippocampus; Immunoprecipitation; Leupeptins; Lithium Chloride; Male; Muscarinic Agonists; Nedd4 Ubiquitin Protein Ligases; Neurons; Pilocarpine; Rats, Sprague-Dawley; RNA, Small Interfering; Time Factors; Transfection; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitins | 2015 |
Ecto-5'-nucleotidase (CD73) is involved in chronic cerebral hypoperfusion-induced white matter lesions and cognitive impairment by regulating glial cell activation and pro-inflammatory cytokines.
Topics: 5'-Nucleotidase; Adenosine Monophosphate; Analysis of Variance; Animals; Carotid Stenosis; Cognition Disorders; Corpus Callosum; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Leukoencephalopathies; Memory, Short-Term; Mice; Mice, Knockout; Neuroglia | 2015 |
5'-adenosine monophosphate-induced hypothermia attenuates brain ischemia/reperfusion injury in a rat model by inhibiting the inflammatory response.
Topics: Adenosine Monophosphate; Animals; Apoptosis; Cerebrovascular Circulation; Disease Models, Animal; Heart Rate; Hypothermia, Induced; Inflammation; Leukocyte Elastase; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Toll-Like Receptors | 2015 |
CXCL14 displays antimicrobial activity against respiratory tract bacteria and contributes to clearance of Streptococcus pneumoniae pulmonary infection.
Topics: Adenosine Monophosphate; Amino Acid Sequence; Animals; Anti-Infective Agents; Cell Membrane; Chemokines, CXC; Chemotaxis; Disease Models, Animal; DNA, Bacterial; Interleukin-8; Lung; Mice; Mice, Knockout; Microbial Sensitivity Tests; Models, Molecular; Myeloblastin; Peptide Fragments; Permeability; Pneumococcal Infections; Protein Binding; Protein Conformation; Protein Interaction Domains and Motifs; Proteolysis; Respiratory Tract Infections; Streptococcus pneumoniae | 2015 |
AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease.
Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Caenorhabditis elegans; Cell Death; Corpus Striatum; Disease Models, Animal; Humans; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neostriatum; Neurons; Phosphorylation; Ribonucleosides | 2016 |
Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adult; Animals; Aspirin; Blood Coagulation; Blood Platelets; Coronary Thrombosis; Dinucleoside Phosphates; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Female; Fibrinolytic Agents; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Time Factors; Young Adult | 2016 |
Methotrexate up-regulates ecto-5'-nucleotidase/CD73 and reduces the frequency of T lymphocytes in the glioblastoma microenvironment.
Topics: 5'-Nucleotidase; Adenosine Monophosphate; Animals; Brain Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Disease Models, Animal; Glioblastoma; Immunohistochemistry; Immunosuppressive Agents; Methotrexate; Rats; T-Lymphocytes; Tumor Escape; Tumor Microenvironment; Up-Regulation | 2016 |
Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa.
Topics: Adenosine Monophosphate; Animals; Antimicrobial Cationic Peptides; Cell Differentiation; Disease Models, Animal; Gene Expression; Interleukin-22; Interleukins; Keratinocytes; Mice; Mice, Knockout; Nasal Mucosa; Staphylococcal Infections; Staphylococcus aureus; T-Lymphocyte Subsets | 2016 |
Effect of Cardiovascular Injury on Catabolism of Adenosine and Adenosine 5-'Triphosphate in Systemic Blood in a Freely Moving Rat Model In Vivo.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiovascular Diseases; Disease Models, Animal; Hypoxanthine; Isoproterenol; Rats; Rats, Sprague-Dawley; Uric Acid | 2016 |
Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Cell Separation; Disease Models, Animal; Homeostasis; Immunohistochemistry; Male; Meninges; Migraine Disorders; Nucleotides; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Purinergic; Trigeminal Ganglion | 2016 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arterial Occlusive Diseases; Blood Coagulation; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hydrolysis; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monocytes; Phenotype; Platelet Activation; Thrombosis; Time Factors; Transfection | 2016 |
Metabolic Profiling of Liver Tissue in Diabetic Mice Treated with Artemisia Capillaris and Alisma Rhizome Using LC-MS and CE-MS.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alisma; Animals; Artemisia; Chromatography, High Pressure Liquid; Chromatography, Liquid; Diabetes Complications; Disease Models, Animal; Electrophoresis, Capillary; Fatty Liver; Lipid Metabolism; Liver; Male; Mass Spectrometry; Mice, Inbred C57BL; Plant Extracts; Purines | 2016 |
Adenosine 5'-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation.
Topics: Acetaminophen; Adenosine Monophosphate; Animals; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Liver; Male; MAP Kinase Kinase Kinase 5; Methylation; Mice, Inbred C57BL; Protective Agents; Proteolysis; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Time Factors; Ubiquitination | 2017 |
Regulation of Expression of Hyperalgesic Priming by Estrogen Receptor α in the Rat.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Monophosphate; Animals; Chronic Pain; Dinoprostone; Disease Models, Animal; DNA, Antisense; Estrogen Receptor alpha; Female; Gene Expression Regulation; Hyperalgesia; Male; Pain Threshold; Rats; Rats, Sprague-Dawley; Ryanodine; Sex Factors; Time Factors; Xanthines | 2017 |
Purinergic enzymatic activities in lymphocytes and cardiomyocytes of mice acutely infected by Trypanosoma cruzi modulating the inflammatory responses.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Chagas Disease; Disease Models, Animal; Female; Heart; Hematologic Tests; Hydrolysis; Lymphocytes; Mice; Myocardium; Myocytes, Cardiac; Parasitemia; Purines; Trypanosoma cruzi | 2017 |
Antibodies as pharmacologic tools for studies on the regulation of energy balance.
Topics: Adenosine Monophosphate; Adipose Tissue; Animals; Anorexia; Antibodies; Body Weight; Diet; Dietary Fats; Disease Models, Animal; Energy Metabolism; Fatty Liver; Feeding Behavior; Humans; Insulin; Lipopolysaccharides; Liver; Male; Organ Size; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Sodium Chloride; Triglycerides | 2008 |
When hypothermia meets hypotension and hyperglycemia: the diverse effects of adenosine 5'-monophosphate on cerebral ischemia in rats.
Topics: Adenosine Monophosphate; Animals; Blood Glucose; Blood Pressure; Body Temperature; Brain Ischemia; Disease Models, Animal; Heart Rate; Hyperglycemia; Hypotension; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Insulin; Male; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2009 |
Time-course changes in ectonucleotidase activities during experimental autoimmune encephalomyelitis.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Cell Membrane; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Multiple Sclerosis; Rats; Rats, Inbred Strains; Spinal Cord; Time Factors | 2009 |
Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics.
Topics: Adenosine Monophosphate; Animals; Benzimidazoles; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Fructose-Bisphosphatase; Humans; Liver; Molecular Structure; Organophosphonates; Rats; Rats, Zucker; Stereoisomerism; Structure-Activity Relationship | 2010 |
Nerve injury-activated microglia engulf myelinated axons in a P2Y12 signaling-dependent manner in the dorsal horn.
Topics: Adenosine Monophosphate; Animals; Calcium-Binding Proteins; Cell Proliferation; Disease Models, Animal; Functional Laterality; Gene Expression Regulation; Hyperalgesia; Male; Microfilament Proteins; Microglia; Microscopy, Immunoelectron; Nerve Fibers, Myelinated; Neuralgia; Posterior Horn Cells; Purinergic P2Y Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2Y12; Signal Transduction; Spinal Cord; Spinal Nerves | 2010 |
SCH 602539, a protease-activated receptor-1 antagonist, inhibits thrombosis alone and in combination with cangrelor in a Folts model of arterial thrombosis in cynomolgus monkeys.
Topics: Adenosine Monophosphate; Animals; Disease Models, Animal; Drug Therapy, Combination; Fibrinolytic Agents; Macaca fascicularis; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptor, PAR-1; Thrombosis | 2010 |
Deficiency or inhibition of CD73 protects in mild kidney ischemia-reperfusion injury.
Topics: 5'-Nucleotidase; Adenosine Monophosphate; Animals; Antigens, CD; Apyrase; Creatinine; Disease Models, Animal; Kidney Diseases; Kidney Function Tests; Mice; Mice, Knockout; Mice, Transgenic; Reperfusion Injury | 2010 |
Transplanted human cord blood-derived unrestricted somatic stem cells preserve high-energy reserves at the site of acute myocardial infarction.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biopsy; Cord Blood Stem Cell Transplantation; Disease Models, Animal; Energy Metabolism; Humans; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Paracrine Communication; Swine; Ventricular Function, Left | 2011 |
BF061, a novel antiplatelet and antithrombotic agent targeting P2Y₁₂ receptor and phosphodiesterase.
Topics: Adenosine; Adenosine Monophosphate; Animals; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Fibrinolytic Agents; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phosphoric Diester Hydrolases; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis | 2011 |
Retinoic acid receptor-related orphan receptor α-induced activation of adenosine monophosphate-activated protein kinase results in attenuation of hepatic steatosis.
Topics: Adenosine Monophosphate; AMP-Activated Protein Kinase Kinases; Animals; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Enzyme Activation; Fatty Liver; Hepatocytes; Lipid Metabolism; Liver X Receptors; Mice; Mice, Inbred Strains; Orphan Nuclear Receptors; Protein Kinases; Random Allocation; Receptors, Retinoic Acid; Reference Values; Retinoic Acid Receptor alpha | 2012 |
The brain in vivo expresses the 2',3'-cAMP-adenosine pathway.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adult; Animals; Brain; Brain Injuries; Cyclic AMP; Disease Models, Animal; Extracellular Fluid; Female; Gene Expression Regulation; Glasgow Coma Scale; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Signal Transduction; Young Adult | 2012 |
Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomarkers; Coronary Circulation; Disease Models, Animal; Endothelium, Vascular; Energy Metabolism; Heart Transplantation; Immunohistochemistry; Male; Metalloporphyrins; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Rats; Rats, Inbred Lew; Time Factors; Tyrosine; Vasodilation; Ventricular Function, Left; Ventricular Pressure | 2012 |
Increased platelet activation and thrombosis in transgenic mice expressing constitutively active P2Y12.
Topics: Adenosine Monophosphate; Animals; Bleeding Time; Blood Platelets; Chlorides; Cyclic AMP; Disease Models, Animal; Drug Inverse Agonism; Ferric Compounds; Fibrinolytic Agents; Genotype; Mice; Mice, Transgenic; Phenotype; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thrombosis | 2012 |
Interleukin-22 modulates gut epithelial and immune barrier functions following acute alcohol exposure and burn injury.
Topics: Adenosine Monophosphate; Alcoholic Intoxication; Animals; Antigens, Neoplasm; Bacterial Load; Biomarkers, Tumor; Burns; Disease Models, Animal; Drug Evaluation, Preclinical; Gene Expression Regulation; Immunity, Mucosal; Interleukin-22; Interleukins; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Lectins, C-Type; Male; Mice; Mice, Inbred C57BL; Pancreatitis-Associated Proteins; Permeability; Proteins; Recombinant Proteins | 2013 |
Blockade of the platelet P2Y12 receptor by AR-C69931MX sustains coronary artery recanalization and improves the myocardial tissue perfusion in a canine thrombosis model.
Topics: Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Animals; Bleeding Time; Blood Coagulation; Coronary Circulation; Coronary Restenosis; Coronary Stenosis; Disease Models, Animal; Dogs; Drug Combinations; Echocardiography; Female; Heparin; Infusions, Intravenous; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Tissue Plasminogen Activator | 2003 |
Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Disease Models, Animal; Humans; Leukocytes; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; P-Selectin; Peptide Fragments; Phosphatidylserines; Plasma; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombin; Thrombosis | 2003 |
Impact of intraischemic temperature on oxidative stress during hepatic reperfusion.
Topics: Adenosine Monophosphate; Animals; Ascorbic Acid; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Female; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxyl Radical; Hypothermia, Induced; Lipid Peroxidation; Liver; Membrane Proteins; Mice; Mice, Inbred C57BL; Microcirculation; Oxidative Stress; Reperfusion; Reperfusion Injury; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1; Temperature | 2003 |
Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Catecholamines; Cell Cycle Proteins; Cerebellum; Corpus Striatum; Disease Models, Animal; Disease Progression; DNA-Binding Proteins; Dopamine; Mesencephalon; Mice; Mice, Knockout; NAD; NADP; Protein Serine-Threonine Kinases; Psychomotor Performance; Sex Factors; Tumor Suppressor Proteins | 2004 |
[Diagnostic effect of bronchoalveolar lavage in early lung injury caused by enterogenic infection in rat].
Topics: Adenosine Monophosphate; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Endotoxins; Female; Male; Oligopeptides; Phospholipases A; Phospholipases A2; Random Allocation; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha | 2004 |
Inhaled prostacyclin reduces cardiopulmonary bypass-induced pulmonary endothelial dysfunction via increased cyclic adenosine monophosphate levels.
Topics: Acetylcholine; Adenosine Monophosphate; Administration, Inhalation; Animals; Antihypertensive Agents; Antioxidants; Biomarkers; Cardiopulmonary Bypass; Cardiovascular Agents; Cyclic AMP; Disease Models, Animal; Endothelium, Vascular; Epoprostenol; Female; Indoles; Lung; Lung Diseases; Male; Models, Cardiovascular; Phenylephrine; Pulmonary Artery; Pulmonary Wedge Pressure; Swine; Vascular Resistance; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2004 |
Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome.
Topics: Adenosine Monophosphate; Amino Acid Substitution; AMP-Activated Protein Kinases; Animals; Binding Sites; Cardiac Pacing, Artificial; Cardiomegaly; Disease Models, Animal; Heart Conduction System; Heart Ventricles; Humans; Mice; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation, Missense; Myocardium; Myosin Heavy Chains; Organ Specificity; Phenotype; Point Mutation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Tachycardia, Atrioventricular Nodal Reentry; Wolff-Parkinson-White Syndrome | 2005 |
Regulation of tissue factor-induced coagulation and platelet aggregation in flowing whole blood.
Topics: Adenosine Monophosphate; Alprostadil; Animals; Blood Coagulation; Disease Models, Animal; Drug Interactions; Fibrin; Fibrinogen; Fibrinolytic Agents; Male; Perfusion; Phosphatidylserines; Platelet Activation; Platelet Aggregation; Rats; Rats, Wistar; Thrombin; Thromboplastin | 2005 |
Influence of ischemic injury on vein graft remodeling: role of cyclic adenosine monophosphate second messenger pathway in enhanced vein graft preservation.
Topics: Adenosine Monophosphate; Animals; Aorta, Abdominal; Blood Vessel Prosthesis; Disease Models, Animal; Graft Rejection; Graft Survival; Jugular Veins; Male; Mice; Mice, Inbred C57BL; Preservation, Biological; Reference Values; Reperfusion Injury; Risk Factors; Sensitivity and Specificity; Tissue and Organ Harvesting; Tissue Transplantation; Tunica Intima; Veins | 2005 |
5'-nucleotidase activity is altered by hypo- and hyperthyroidism in platelets from adult rats.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Platelets; Disease Models, Animal; Hyperthyroidism; Hypothyroidism; Male; Rats; Rats, Wistar; Thyroxine | 2005 |
Protein kinase C inhibits cyclic adenosine monophosphate-induced calcium-activated and voltage-activated potassium channel activity in fawn-hooded rat pulmonary arterial smooth muscle via phosphodiesterases.
Topics: Adenosine Monophosphate; Animals; Calcium; Disease Models, Animal; Hypertension, Pulmonary; Muscle, Smooth, Vascular; Phosphoric Diester Hydrolases; Potassium Channels; Protein Kinase C; Pulmonary Artery; Rats; Signal Transduction | 2005 |
Enhanced cardiovascular function and energy level by a novel chromium (III)-supplement.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apoptosis; Aspartate Aminotransferases; Blotting, Western; Body Weight; Chromium Compounds; Coronary Circulation; Dietary Supplements; Disease Models, Animal; Female; Heart Rate; Lipid Peroxidation; Male; Models, Biological; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphocreatine; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley | 2006 |
P2X purinergic receptor-mediated ionic current in cardiac myocytes of calsequestrin model of cardiomyopathy: implications for the treatment of heart failure.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzenesulfonates; Calsequestrin; Cardiac Output, Low; Cardiomyopathies; Disease Models, Animal; Disease Progression; Membrane Potentials; Mice; Mice, Transgenic; Myocytes, Cardiac; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Thionucleotides | 2007 |
Effect of a specific and selective A(2B) adenosine receptor antagonist on adenosine agonist AMP and allergen-induced airway responsiveness and cellular influx in a mouse model of asthma.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Administration, Inhalation; Aerosols; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Plethysmography; Purines; Pyrazoles | 2007 |
A1 adenosine receptor upregulation accompanies decreasing myocardial adenosine levels in mice with left ventricular dysfunction.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Female; Heart Failure; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Myocardium; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation; Ventricular Dysfunction, Left | 2007 |
Dexamethasone enhances adenosine 5'-triphosphate-sensitive potassium channel expression in the blood-brain tumor barrier in a rat brain tumor model.
Topics: Adenosine Monophosphate; Analysis of Variance; Animals; Antineoplastic Agents, Hormonal; Blood-Brain Barrier; Bradykinin; Brain Neoplasms; Cell Line, Tumor; Dexamethasone; Disease Models, Animal; Drug Interactions; Female; Glioma; Membrane Potentials; Patch-Clamp Techniques; Permeability; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Thionucleotides; Xenograft Model Antitumor Assays | 2007 |
CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury.
Topics: Adenosine; Adenosine Monophosphate; Animals; Antigens, CD; Apyrase; Disease Models, Animal; Enzyme Induction; Ischemic Preconditioning, Myocardial; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium | 2007 |
Effect of halothane on adenylate kinase in porcine malignant hyperpyrexia.
Topics: Adenosine Monophosphate; Adenylate Kinase; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Phosphotransferases; Swine | 1982 |
[The system of active transport of organic acids in the proximal tubules of rats with hereditary retinal degeneration (Campbell strain)].
Topics: Adenosine; Adenosine Monophosphate; Animals; Bile Acids and Salts; Biological Transport, Active; Disease Models, Animal; Fluoresceins; Hippurates; Kidney Tubules, Proximal; Male; Nephrectomy; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Retinitis Pigmentosa; Uric Acid | 1983 |
Metabolic studies of postischemic acute renal failure in the rat.
Topics: Acute Kidney Injury; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Ischemia; Kidney; Lactates; Lactic Acid; Male; Phosphates; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Human urinary trypsin inhibitor, urinastatin, prevents pancreatic injuries induced by pancreaticobiliary duct obstruction with cerulein stimulation and systemic hypotension in the rat.
Topics: Acute Disease; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amylases; Animals; Cathepsin B; Ceruletide; Cholestasis; Disease Models, Animal; Drug Evaluation, Preclinical; Glycoproteins; Hypotension; Infusions, Intravenous; Malate Dehydrogenase; Male; Pancreatitis; Rats; Rats, Wistar; Trypsin; Trypsin Inhibitors | 1993 |
Inositol trisphosphate, polyphosphoinositide turnover, and high-energy metabolites in focal cerebral ischemia and reperfusion.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Calcium; Carotid Artery, Common; Cerebral Arteries; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Homeostasis; Hydrolysis; Inositol 1,4,5-Trisphosphate; Ischemic Attack, Transient; Neurons; Phosphatidylinositol Phosphates; Rats; Reperfusion; Signal Transduction; Tritium | 1995 |
Enhancement of ischemic myocardial metabolic derangement by glibenclamide.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Dogs; Energy Metabolism; Female; Fructosephosphates; Glucose-6-Phosphate; Glucosephosphates; Glyburide; Heart; Heart Rate; Insulin; Male; Myocardial Ischemia; Myocardium; Phosphocreatine; Potassium Channels | 1994 |
Antiischaemic effect of defibrotide treatment in rat kidney.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Fibrinolytic Agents; Ischemia; Kidney; Male; Polydeoxyribonucleotides; Rats; Rats, Wistar; Reperfusion Injury | 1993 |
Effect of standard-dose versus high-dose epinephrine on myocardial high-energy phosphates during ventricular fibrillation and closed-chest CPR.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biopsy; Blood Gas Analysis; Cardiopulmonary Resuscitation; Chromatography, High Pressure Liquid; Clinical Protocols; Disease Models, Animal; Drug Evaluation, Preclinical; Epinephrine; Guanosine Triphosphate; Heart Arrest; Hemodynamics; Injections, Intravenous; Inosine; Inosine Monophosphate; Myocardium; Phosphocreatine; Swine; Ventricular Fibrillation | 1993 |
Diabetic cardiomyopathy in rats: alleviation of myocardial dysfunction caused by Ca2+ overload.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Calcium; Cardiomyopathies; Diabetes Mellitus, Experimental; Disease Models, Animal; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Rats; Rats, Wistar | 1996 |
Skeletal muscle metabolism in experimental heart failure.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Disease Models, Animal; Female; Heart Failure; Monocrotaline; Muscle, Skeletal; NAD; Organ Size; Oxidation-Reduction; Phosphocreatine; Rats; Rats, Sprague-Dawley | 1996 |
Changes in adenine nucleotides and lipid hydroperoxides during normothermic cardiopulmonary bypass in a porcine model of type II non-heart-beating donor.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiopulmonary Bypass; Disease Models, Animal; Glutathione; Heart Arrest; Lipid Peroxides; Liver; Resuscitation; Swine; Tissue Donors | 1997 |
Calcium equally increases the internal calcium recirculation fraction before and after beta-blockade in canine left ventricles.
Topics: Adenosine Monophosphate; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channels; Coronary Vessels; Disease Models, Animal; Dogs; Electrocardiography; Heart Ventricles; Injections, Intra-Arterial; Myocardial Contraction; Propranolol | 1997 |
Effect of transient focal ischemia of mouse brain on energy state and NAD levels: no evidence that NAD depletion plays a major role in secondary disturbances of energy metabolism.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Disease Models, Animal; Energy Metabolism; Fluorescence; Ischemic Attack, Transient; Luminescent Measurements; Male; Mice; Mice, Inbred C57BL; NAD; Organ Specificity; Poly(ADP-ribose) Polymerases | 2000 |
Prevention of arterial thrombosis by intravenously administered platelet P2T receptor antagonist AR-C69931MX in a canine model.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Arterial Occlusive Diseases; Bleeding Time; Blood Flow Velocity; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Disease Models, Animal; Dogs; Female; Hemodynamics; Injections, Intravenous; Male; Membrane Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Tunica Intima | 2000 |
Blood purine and energy status in rats with colitis.
Topics: Acetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomarkers; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Energy Metabolism; Hemoglobins; Inosine; Male; Peroxidase; Purines; Rats; Rats, Wistar; Time Factors; Uric Acid | 2001 |
[Changes in energy metabolism in the brain of bemegride-kindled rabbits].
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bemegride; Cerebral Cortex; Convulsants; Disease Models, Animal; Energy Metabolism; Epilepsy; Kindling, Neurologic; Male; Mitochondria; Oxygen; Rabbits | 2002 |
The ocular anti-inflammatory action of imidazole.
Topics: Adenosine Monophosphate; Animals; Anti-Inflammatory Agents; Aqueous Humor; Conjunctivitis; Disease Models, Animal; Endotoxins; Eye; Guanine Nucleotides; Imidazoles; Phosphoric Diester Hydrolases; Rabbits; Shigella; Uveitis; Vitreous Body | 1977 |
Genital Herpesvirus homonis infection in mice. II. Treatment with phosphonoacetic acid, adenine arabinoside, and adenine arabinoside 5'-monophosphate.
Topics: Adenosine Monophosphate; Animals; Disease Models, Animal; Female; Herpes Simplex; Mice; Organophosphorus Compounds; Simplexvirus; Vagina; Vaginal Diseases; Vidarabine; Virus Replication | 1977 |
Elevation of rat erythrocyte nucleotide levels following acute renal failure induced by glycerol or mercuric chloride.
Topics: Acute Kidney Injury; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chlorides; Creatinine; Disease Models, Animal; Erythrocytes; Female; Glycerol; Guanosine Diphosphate; Guanosine Triphosphate; Mercury; Nucleotides; Phosphates; Rats; Urea | 1978 |
Herpes simplex keratitis: animal models to guide the selection and optimal delivery of antiviral chemotherapy.
Topics: Adenosine Monophosphate; Animals; Antiviral Agents; Cornea; Disease Models, Animal; Drug Evaluation, Preclinical; Hypoxanthines; Keratitis, Dendritic; Rabbits; Vidarabine | 1977 |
Splanchnic organ adenine nucleotides and their netabolites in haemorrhagic shock.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Dogs; Duodenum; Liver; Pancreas; Shock, Hemorrhagic | 1977 |
Hepatic metabolic changes following energy deprivation by ammonia in patients and rabbits with jaundice.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonia; Ammonium Chloride; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Cholestasis; Disease Models, Animal; Humans; Liver; Male; Mitochondria, Liver; Ornithine Carbamoyltransferase; Rabbits | 1977 |
Sephadex-induced reduction of coronary flow in the isolated rat heart: a model for ischemic heart disease.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Coronary Disease; Disease Models, Animal; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Male; Microspheres; Myocardial Contraction; Myocardium; Perfusion; Phosphocreatine; Polysaccharides; Rats; Sepharose | 1977 |
A model of graded ischemia in the isolated perfused rat heart.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Glucose; Glycogen; Hemodynamics; In Vitro Techniques; Lactates; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphocreatine; Rats | 1976 |
Metabolic responses to varying restrictions of coronary blood flow in swine.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Energy Metabolism; Fatty Acids; Female; Glucose; Glycogen; Heart; Lactates; Male; Myocardium; Oxygen Consumption; Regional Blood Flow; Swine; Ventricular Fibrillation | 1975 |
Resuscitation of the monkey brain after one hour complete ischemia. III. Indications of metabolic recovery.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosylmethionine Decarboxylase; Animals; Brain; Cerebrovascular Circulation; Disease Models, Animal; Electroencephalography; Energy Metabolism; Female; Glucose; Ischemic Attack, Transient; Lactates; Macaca mulatta; Male; Nerve Tissue Proteins; Ornithine Decarboxylase; Phosphocreatine; Polyribosomes; Pyruvates; Time Factors | 1975 |
Correlation between coronary venous inosine concentration and myocardial wall thickening during regional ischemia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Membrane; Coronary Disease; Coronary Vessels; Disease Models, Animal; Heart; Inosine; Myocardium; Swine | 1975 |
Effect on myocardial metabolic pattern of local complete and incomplete ischemia.
Topics: Adenosine Monophosphate; Animals; Coronary Disease; Creatine; Disease Models, Animal; Dogs; Glycogen; Heart Ventricles; Lactates; Myocardial Infarction; Myocardium; Phosphocreatine; Time Factors | 1975 |
Effects of coronary perfusion during myocardial hypoxia. Comparison of metabolic and hemodynamic events with global ischemia and hypoxemia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Disease; Disease Models, Animal; Female; Glucose; Glycogen; Heart; Hemodynamics; Hypoxia; Lactates; Male; Myocardial Revascularization; Myocardium; Oxygen Consumption; Phosphocreatine; Swine | 1976 |
Cerebral amino acids and energy metabolites in the growth retarded rat fetus under normoxia and hypoxia.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Animals; Brain Chemistry; Disease Models, Animal; Energy Metabolism; Female; Fetal Growth Retardation; Fetus; gamma-Aminobutyric Acid; Hypoxia; Pregnancy; Rats; Rats, Sprague-Dawley | 1992 |
Biochemical appraisal of models for hepatic ischemia-reperfusion injury.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Disease Models, Animal; Ischemia; Liver; Male; Rats; Rats, Inbred Strains; Reperfusion Injury | 1992 |
[Effect of nucleotide anti-aggregants (NAD, AMP) and ischemia on the tissue blood coagulation factors].
Topics: Adenosine Monophosphate; Animals; Blood Coagulation; Disease Models, Animal; Ischemia; Kidney; Male; NAD; Platelet Aggregation Inhibitors; Rabbits; Rats; Thromboplastin | 1991 |
Myocardial high-energy phosphate levels in cardiomyopathic turkeys.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomyopathy, Dilated; Disease Models, Animal; Myocardium; Phosphocreatine; Turkeys | 1986 |
Relation between changes in the acid-base and the energy metabolism of the brain in hepatic coma.
Topics: Acid-Base Equilibrium; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bicarbonates; Brain; Carbon Dioxide; Disease Models, Animal; Hemoglobins; Hepatectomy; Hepatic Encephalopathy; Hydrogen-Ion Concentration; Lactates; Male; NAD; Oxygen; Partial Pressure; Phosphocreatine; Pyruvates; Rats | 1971 |
Vitamin A deficiency stimulated phosphatase activity in epiphyseal chick cartilage.
Topics: Acid Phosphatase; Adenosine Monophosphate; Alkaline Phosphatase; Animals; Bone Development; Cartilage; Chickens; Disease Models, Animal; Epiphyses; Osteogenesis; Phosphates; Phosphoric Monoester Hydrolases; Pyrophosphatases; Vitamin A Deficiency | 1974 |
Effects of ischemia on function and metabolism of the isolated working rat heart.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Heart; Heart Failure; Lactates; Male; Myocardium; Oxygen Consumption; Phosphocreatine; Rats; Regional Blood Flow; Time Factors | 1973 |
Graded hypoxia-oligemia in rat brain. I. Biochemical alterations and their implications.
Topics: Acidosis; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Carbon Dioxide; Cerebrovascular Circulation; Disease Models, Animal; Glucosephosphates; Hypoxia; Hypoxia, Brain; Ischemic Attack, Transient; Keto Acids; Lactates; Ligation; Malates; Nitrogen; Oxygen; Oxygen Consumption; Partial Pressure; Phosphocreatine; Rats | 1973 |
[Effect of intra-aortic balloon counterpulsation on the hemodynamics and the metabolism of the non-ischemic and ischemic left heart ventricle].
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Assisted Circulation; Blood Pressure; Disease Models, Animal; Dogs; Heart; Heart Ventricles; Hemodynamics; Lactates; Ligation; Myocardial Infarction; Myocardium; Shock, Cardiogenic | 1973 |
Effect of galactose-ethanol feeding on growth in rats.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Body Weight; Diet; Disease Models, Animal; Ethanol; Galactose; Galactosemias; Growth; Hexosediphosphates; Hexosephosphates; Liver; Rats; Uridine Diphosphate Sugars | 1974 |
Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia.
Topics: Acid-Base Equilibrium; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Carbohydrate Metabolism; Carbon Dioxide; Citrates; Disease Models, Animal; Glucose; Glutamates; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Nucleotidases; Oxidation-Reduction; Partial Pressure; Phosphocreatine; Pyruvates; Rats | 1974 |
Cerebral metabolic state following complete compression ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Blood Pressure; Carbohydrate Metabolism; Carbon Dioxide; Cerebral Cortex; Citric Acid Cycle; Disease Models, Animal; Electroencephalography; Glucose; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Mitochondria; Nucleotidases; Oxygen; Partial Pressure; Phosphocreatine; Pyruvates; Rats; Time Factors | 1974 |