Page last updated: 2024-08-17

adenosine monophosphate and Blood Clot

adenosine monophosphate has been researched along with Blood Clot in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-19903 (4.92)18.7374
1990's1 (1.64)18.2507
2000's13 (21.31)29.6817
2010's31 (50.82)24.3611
2020's13 (21.31)2.80

Authors

AuthorsStudies
Bhatt, DL; Cavender, MA; Deliargyris, EN; Gibson, CM; Hamm, CW; Harrington, RA; Leonardi, S; Lopes, RD; Mahaffey, KW; Prats, J; Price, MJ; Steg, PG; Stone, GW; White, HD1
Cheng, XD; Li, YJ; Wang, JH; Wang, L; Yang, B; Yang, X; Yu, NW; Zhang, J; Zhang, Q; Zhang, X1
Ahmed, Y; Avery, M; Booth, Z; Calaminus, SDJ; Coupland, CA; Firth, G; Gil, HM; Naylor-Adamson, L; Price, TW; Stasiuk, GJ1
Berry, TP; Haines, MM; Hayes, CH; Kozinn, JB; Mohamed, AM; Pluenneke, JC; Thomas, EL; Welge, JA; Zhurav, L1
Boncler, M; Gapinska, M; Polak, D; Przygodzki, T; Rozalski, M; Watala, C; Wolska, N; Wzorek, J1
Bozzi, S; Cattaneo, M; Mencarini, T; Podda, G; Redaelli, A; Scavone, M1
Finniss, M; Helton, T; Khalid, M; Khan, AA; Murtaza, G1
Di Perri, G1
Alexander, J; Allada, V; Allen, B; Bacha, E; Diacovo, T; Diamond, S; Kreutzer, J; Krishnamurthy, G; Morell, V; Price, M; Schmidhofer, J; Vargas, D; Vincent, J; Yeh, J; Yu, X; Zhou, H1
Berkman, SA; Tapson, VF1
Bonda, TA; Karolczak, K; Kramkowski, K; Polak, D; Przygodzki, T; Talar, M; Watala, C; Wojkowska, DW; Wolska, N1
Anedda, L; Bianchini, L; Cuzzolin, L; Fanos, V; Finco, G; Marcialis, MA1
Fan, D; Li, Q; Ma, LJ; Mao, YH; Tian, Z; Wan, JB; Ya, F; Yang, Y; Zhao, M; Zhao, Y; Zuo, X1
Angiolillo, DJ; Bhatt, DL; Capodanno, D; De Luca, L; Steg, PG1
Chang, L; Ding, Z; Hu, L; Kunapuli, SP; Luo, X; Qi, Z; Wang, Y; Yan, H; Yan, Y; Ye, H; Zhai, L; Zhang, S; Zhang, Y1
Farag, M; Gorog, DA; Gue, YX; Spinthakis, N; Srinivasan, M; Wellsted, DM1
Abtan, J; Bhatt, DL; Deliargyris, EN; Ducrocq, G; Elkin, S; Gibson, CM; Hamm, C; Harrington, RA; Mahaffey, KW; Menozzi, A; Prats, J; Price, MJ; Steg, PG; Stone, GW; White, HD1
Bernardo, NL; Chen, Y; Waksman, R1
Chen, Y; Khalid, N; Rogers, T; Shlofmitz, E; Waksman, R1
Dash, D; Gautam, D; Nath Chaurasia, R; Tiwari, A1
Hillis, LD; Lange, RA1
Angiolillo, DJ; Bhatt, DL; Bramucci, E; Gallup, D; Généreux, P; Gibson, CM; Hamm, CW; Harrington, RA; Leonardi, S; Liu, T; Mahaffey, KW; McLaurin, BT; Prats, J; Price, MJ; Radke, PW; Skerjanec, S; Spriggs, D; Steg, PG; Stone, GW; Tauth, J; Todd, M; Tousek, F; White, HD; Widimský, P1
Riezebos, RK; Verheugt, FW1
Bhatt, DL; Harrington, RA1
Wong, BY1
Chatterjee, S; Mushiyev, S; Nairooz, R; Pekler, G; Sardar, P; Visco, F1
Aryal Pandit, A; Aryal, MR; Hakim, FA; Jalota, L; Lee, HR; Mookadam, F; Pandit, A; Tleyjeh, IM1
Angiolillo, DJ; Bhatt, DL; Brener, SJ; Généreux, P; Gibson, CM; Hamm, CW; Harrington, RA; LaSalle, L; Liu, T; Mahaffey, KW; Prats, J; Price, MJ; Skerjanec, S; Steg, PG; Stone, GW; Todd, M; White, HD1
DiNicolantonio, JJ; Fortmann, SD; Pokov, AN; Serebruany, VL1
Alarcón, M; Badimon, L; Caballero, J; Fuentes, E; Padró, T; Palomo, I; Pérez, P; Vilahur, G1
Guasti, L; Riva, N; Squizzato, A; Tamborini Permunian, E1
Sinha, A; Storey, RF1
Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG1
Adamska, U; Adamski, P; Koziński, M; Kubica, J; Ostrowska, M1
Bhatt, DL; Qamar, A1
Abu-Fadel, M; Norgard, NB1
Faxon, DP1
Ruparelia, N; Spyrou, N1
Caicedo, J; Dong, A; Gairola, CG; Han, SG; Mueller, P; Saha, S; Smyth, SS1
Chintala, M; Kurowski, S; Li, Q; Strony, J; Yang, B1
Storey, RF1
Ding, Z; Du, H; Fan, Z; Gross, PL; Hu, L; Kunapuli, SP; Ni, R; Wei, X; Ye, J; Yin, K; Zhang, S; Zhang, X; Zhang, Y1
Angiolillo, DJ; Brtko, M; Cannon, L; Chandna, H; Dyke, C; Firstenberg, MS; Hutyra, M; Liu, T; Manoukian, SV; Montalescot, G; Prats, J; Price, MJ; Ramaiah, C; Topol, EJ; Tummala, PE; Voeltz, MD; Welsby, IJ1
Barn, K; Steinhubl, SR1
Ding, Z; Hu, L; Kunapuli, SP; Li, Y; Ye, J; Zhang, S; Zhang, SH; Zhang, Y1
Nurden, AT; Nurden, P1
Carneiro, M; Humphries, RG; Klein, A; Lincoff, AM; Murray, D; Penn, MS; Tarakji, K; Thomas, JD; Topol, EJ; Turner, J; Wang, K; Zhou, X; Zhou, Z1
Cazenave, JP; Freund, M; Gachet, C; Leon, C; Ravanat, C1
BRUNELLE, AR; O'BRIEN, FL; TOSI, GA1
Campbell, DJ; Cowan, PJ; d'Apice, AJ; Dwyer, KM; Fisicaro, N; Gock, H; Kaczmarek, E; Murray-Segal, LJ; Mysore, TB; Nandurkar, HH; Robson, SC1
Boeynaems, JM; Herbert, JM; Savi, P; van Giezen, H1
Humphries, RG; van Giezen, JJ1
Goto, S; Ishida, H; Ruggeri, ZM; Tamura, N1
Brandl, R; Deckmyn, H; Penz, SM; Reininger, AJ; Siess, W; Toth, O1
Bauchspiess, K; da Silva, JE; Leal, CA; Leal, DB; Maldonado, PA; Morsch, VM; Schetinger, MR; Schrekker, CM1
Angiolillo, DJ1
Bailey, A; Clegg, JA; Coombs, ME; Cox, D; Dixon, J; Humphries, RG; Hunt, SF; Ingall, AH; Kindon, ND; Leff, P; McInally, JI; Smith, JA; Teobald, BJ; Tomlinson, W; Willis, PA1
Kirichuk, VF; Pozin, PIa; Rebrov, AP; Voskoboĭ, IV1
de Groot, PG; IJsseldijk, MJ; Jeninga, EH; Nurden, AT; Nurden, P; Remijn, JA; Sixma, JJ; van Willigen, G; Wu, YP1
Lewis, GP; Lieberman, GE; Peters, TJ1
König, J; Mlejnková, M; Rysánek, K; Spánková, H1

Reviews

17 review(s) available for adenosine monophosphate and Blood Clot

ArticleYear
Purinergic signaling: a potential therapeutic target for ischemic stroke.
    Purinergic signalling, 2023, Volume: 19, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Antigens, CD; Apyrase; Humans; Ischemic Stroke; Signal Transduction; Thrombosis

2023
COVID-19 and Its Implications for Thrombosis and Anticoagulation.
    Seminars in respiratory and critical care medicine, 2021, Volume: 42, Issue:2

    Topics: Adenosine Monophosphate; Alanine; Ambulatory Care; Antibodies, Antiphospholipid; Antibodies, Monoclonal, Humanized; Anticoagulants; Antirheumatic Agents; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Dose-Response Relationship, Drug; Drug Combinations; Duration of Therapy; Glucocorticoids; Hospitalization; Humans; Hydroxychloroquine; Immunization, Passive; Lopinavir; Ritonavir; SARS-CoV-2; Thrombolytic Therapy; Thrombophilia; Thrombosis; Venous Thromboembolism

2021
What if COVID-19 affects the child: which weapons and how to use them.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:8

    Topics: Adenosine Monophosphate; Adolescent; Age Factors; Alanine; Antibodies, Monoclonal, Humanized; Anticoagulants; Antiviral Agents; Carrier State; Child; Child, Preschool; Chloroquine; Continuous Renal Replacement Therapy; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Drug Combinations; Extracorporeal Membrane Oxygenation; Glucocorticoids; Humans; Hydroxychloroquine; Immunization, Passive; Immunoglobulins, Intravenous; Immunologic Factors; Infant; Infant, Newborn; Interferon-alpha; Lopinavir; Oseltamivir; Receptors, Cell Surface; Respiration, Artificial; Ribavirin; Ritonavir; SARS-CoV-2; Severity of Illness Index; Thrombosis

2021
Cangrelor: Clinical Data, Contemporary Use, and Future Perspectives.
    Journal of the American Heart Association, 2021, 07-06, Volume: 10, Issue:13

    Topics: Acute Coronary Syndrome; Adenosine Monophosphate; Animals; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Risk Assessment; Risk Factors; Thrombosis; Treatment Outcome

2021
Cangrelor for patients undergoing percutaneous coronary intervention: evidence from a meta-analysis of randomized trials.
    Journal of thrombosis and thrombolysis, 2014, Volume: 38, Issue:1

    Topics: Adenosine Monophosphate; Female; Hemorrhage; Humans; Male; Models, Biological; Myocardial Infarction; Percutaneous Coronary Intervention; Postoperative Complications; PubMed; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Thrombosis

2014
Cangrelor versus clopidogrel in percutaneous coronary intervention: a systematic review and meta-analysis.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2014, Mar-20, Volume: 9, Issue:11

    Topics: Adenosine Monophosphate; Clopidogrel; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stents; Thrombosis; Ticlopidine

2014
Cangrelor for the treatment of arterial thrombosis: pharmacokinetics/pharmacodynamics and clinical data.
    Expert opinion on drug metabolism & toxicology, 2015, Volume: 11, Issue:4

    Topics: Adenosine Monophosphate; Coronary Artery Disease; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thrombosis

2015
Cangrelor for the management and prevention of arterial thrombosis.
    Expert review of cardiovascular therapy, 2016, Volume: 14, Issue:9

    Topics: Adenosine Monophosphate; Administration, Intravenous; Clopidogrel; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis; Ticlopidine

2016
New directions for pharmacotherapy in the treatment of acute coronary syndrome.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:17

    Topics: Acute Coronary Syndrome; Adenosine Monophosphate; Antibodies, Monoclonal; Anticholesteremic Agents; Clinical Trials as Topic; Drug Discovery; Ezetimibe; Humans; PCSK9 Inhibitors; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis; Treatment Outcome

2016
Optimizing the Use of Cangrelor in the Real World.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2017, Volume: 17, Issue:1

    Topics: Adenosine Monophosphate; Animals; Clinical Trials as Topic; Coronary Artery Disease; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis

2017
Future prospects in anti-platelet therapy: a review of potential P2Y12 and thrombin receptor antagonists.
    Recent patents on cardiovascular drug discovery, 2008, Volume: 3, Issue:3

    Topics: Adenosine Monophosphate; Animals; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Receptors, Thrombin; Thiophenes; Thrombosis

2008
Pharmacology and clinical trials of reversibly-binding P2Y12 inhibitors.
    Thrombosis and haemostasis, 2011, Volume: 105 Suppl 1

    Topics: Adenosine; Adenosine Monophosphate; Animals; Clinical Trials, Phase III as Topic; Clopidogrel; Humans; Piperazines; Platelet Activation; Prasugrel Hydrochloride; Protein Binding; Purinergic P2Y Receptor Antagonists; Quinazolinones; Sulfonamides; Thiophenes; Thrombosis; Ticagrelor; Ticlopidine

2011
A brief review of the past and future of platelet P2Y12 antagonist.
    Coronary artery disease, 2012, Volume: 23, Issue:6

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Piperazines; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Quinazolinones; Stents; Sulfonamides; Thiophenes; Thrombosis; Ticagrelor; Ticlopidine

2012
Advantages of fast-acting ADP receptor blockade in ischemic heart disease.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Feb-01, Volume: 23, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Drug Combinations; Humans; Myocardial Ischemia; Platelet Activation; Platelet Aggregation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Thrombosis; Tissue Plasminogen Activator

2003
P2Y receptor antagonists in thrombosis.
    Current opinion in investigational drugs (London, England : 2000), 2005, Volume: 6, Issue:3

    Topics: Adenosine Monophosphate; Animals; Clopidogrel; Humans; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Thrombosis; Ticlopidine

2005
Preclinical and clinical studies with selective reversible direct P2Y12 antagonists.
    Seminars in thrombosis and hemostasis, 2005, Volume: 31, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Administration, Oral; Animals; Arterial Occlusive Diseases; Clinical Trials as Topic; Dogs; Double-Blind Method; Drug Evaluation, Preclinical; Female; Fibrinolytic Agents; Humans; Injections, Intravenous; Male; Membrane Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Rabbits; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Thrombosis; Ticagrelor

2005
ADP receptor antagonism: what's in the pipeline?
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2007, Volume: 7, Issue:6

    Topics: Adenosine; Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Blood Platelets; Clopidogrel; Coronary Disease; Humans; Membrane Proteins; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Thrombosis; Ticagrelor; Ticlopidine

2007

Trials

6 trial(s) available for adenosine monophosphate and Blood Clot

ArticleYear
Ischemic Events Occur Early in Patients Undergoing Percutaneous Coronary Intervention and Are Reduced With Cangrelor: Findings From CHAMPION PHOENIX.
    Circulation. Cardiovascular interventions, 2022, Volume: 15, Issue:1

    Topics: Adenosine Monophosphate; Clopidogrel; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis; Treatment Outcome

2022
Characteristics and outcomes of patients requiring bailout use of glycoprotein IIb/IIIa inhibitors for thrombotic complications of percutaneous coronary intervention: An analysis from the CHAMPION PHOENIX trial.
    International journal of cardiology, 2019, Mar-01, Volume: 278

    Topics: Adenosine Monophosphate; Aged; Double-Blind Method; Female; Heart Diseases; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; ST Elevation Myocardial Infarction; Thrombosis; Treatment Outcome

2019
Effect of platelet inhibition with cangrelor during PCI on ischemic events.
    The New England journal of medicine, 2013, Apr-04, Volume: 368, Issue:14

    Topics: Adenosine Monophosphate; Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Double-Blind Method; Female; Hemorrhage; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2013
Impact of intraprocedural stent thrombosis during percutaneous coronary intervention: insights from the CHAMPION PHOENIX Trial (Clinical Trial Comparing Cangrelor to Clopidogrel Standard of Care Therapy in Subjects Who Require Percutaneous Coronary Interv
    Journal of the American College of Cardiology, 2014, Feb-25, Volume: 63, Issue:7

    Topics: Adenosine Monophosphate; Aged; Clopidogrel; Double-Blind Method; Female; Humans; Intraoperative Complications; Male; Middle Aged; Percutaneous Coronary Intervention; Prospective Studies; Standard of Care; Stents; Thrombosis; Ticlopidine; Treatment Outcome

2014
Bridging antiplatelet therapy with cangrelor in patients undergoing cardiac surgery: a randomized controlled trial.
    JAMA, 2012, Jan-18, Volume: 307, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine Monophosphate; Adult; Aged; Aged, 80 and over; Blood Loss, Surgical; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Purinergic P2Y Receptor Antagonists; Stents; Thienopyridines; Thrombosis

2012
[Lectin-induced platelet aggregation inpatients with unstable angina pectoris treated with anti-aggregation agents].
    Klinicheskaia meditsina, 2001, Volume: 79, Issue:4

    Topics: Adenosine Monophosphate; Angina, Unstable; Blood Platelets; Female; Humans; Lectins; Male; Middle Aged; Phytohemagglutinins; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine

2001

Other Studies

38 other study(ies) available for adenosine monophosphate and Blood Clot

ArticleYear
Platelet zinc status regulates prostaglandin-induced signaling, altering thrombus formation.
    Journal of thrombosis and haemostasis : JTH, 2023, Volume: 21, Issue:9

    Topics: Adenosine Monophosphate; Adenylyl Cyclases; Blood Platelets; Chelating Agents; Cyclic AMP; Epoprostenol; Humans; Platelet Aggregation; Prostaglandins; Thrombosis; Zinc

2023
Evaluation of Cangrelor Use After Percutaneous Coronary Intervention in Patients With Mechanical Circulatory Support.
    Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:12

    Topics: Adenosine Monophosphate; Adolescent; Cohort Studies; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Thrombosis; Treatment Outcome

2023
Adenosine Receptor Agonists Exhibit Anti-Platelet Effects and the Potential to Overcome Resistance to P2Y
    Molecules (Basel, Switzerland), 2019, Dec-28, Volume: 25, Issue:1

    Topics: Adenosine Monophosphate; Drug Resistance; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P1 Receptor Agonists; Receptors, Purinergic P2Y12; Thrombosis

2019
Platelet Adhesion and Thrombus Formation in Microchannels: The Effect of Assay-Dependent Variables.
    International journal of molecular sciences, 2020, Jan-23, Volume: 21, Issue:3

    Topics: Adenosine Monophosphate; Aspirin; Blood Platelets; Collagen; Cyclooxygenase Inhibitors; Humans; Male; Microfluidics; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis; Young Adult

2020
Efficacy of Cangrelor as Bridging Therapy Post PCI.
    Cardiovascular & hematological disorders drug targets, 2020, Volume: 20, Issue:3

    Topics: Adenosine Monophosphate; Aged; Aspirin; Colectomy; Colonic Neoplasms; Drug-Eluting Stents; Factor Xa Inhibitors; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Pyrazoles; Pyridones; Thrombosis; Ticagrelor

2020
The rationale for Low-Molecular Weight Heparin (LMWH) use in SARS-CoV-2 infection
    Le infezioni in medicina, 2020, 06-01, Volume: 28, Issue:suppl 1

    Topics: Adenosine Monophosphate; Alanine; Anticoagulants; Antiviral Agents; Biomarkers; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Critical Care; Disease Management; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Embolism; Endothelium, Vascular; Heparin, Low-Molecular-Weight; Humans; Hydroxychloroquine; Interferon beta-1b; Lopinavir; Macrophage Activation; Pandemics; Pneumonia, Viral; Pulmonary Fibrosis; Randomized Controlled Trials as Topic; Ritonavir; Thromboembolism; Thrombophilia; Thrombosis

2020
Cangrelor PK/PD analysis in post-operative neonatal cardiac patients at risk for thrombosis.
    Journal of thrombosis and haemostasis : JTH, 2021, Volume: 19, Issue:1

    Topics: Adenosine Monophosphate; Anticoagulants; Humans; Infant, Newborn; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Thrombosis; Venous Thromboembolism

2021
Adenosine Receptor Agonist HE-NECA Enhances Antithrombotic Activities of Cangrelor and Prasugrel in vivo by Decreasing of Fibrinogen Density in Thrombus.
    International journal of molecular sciences, 2021, Mar-17, Volume: 22, Issue:6

    Topics: Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Adult; Animals; Antithrombins; Blood Pressure; Blood-Brain Barrier; Chlorides; Diastole; Female; Ferric Compounds; Fibrinogen; Humans; Laser-Doppler Flowmetry; Male; Mice, Inbred C57BL; Permeability; Platelet Activation; Platelet Aggregation; Prasugrel Hydrochloride; Purinergic P1 Receptor Agonists; Purinergic P2Y Receptor Antagonists; Systole; Thrombosis

2021
Ginsenosides Rb2 and Rd2 isolated from
    Food & function, 2021, Jul-05, Volume: 12, Issue:13

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Flowers; Ginsenosides; Humans; Mice; Mice, Inbred C57BL; Panax notoginseng; Phosphatidylinositol 3-Kinases; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; Thrombosis

2021
Platelets Express Activated P2Y
    Circulation, 2017, Aug-29, Volume: 136, Issue:9

    Topics: Adenosine Monophosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Cell Line; Chlorides; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Inverse Agonism; Ferric Compounds; Fibrinolytic Agents; Humans; Male; Microfilament Proteins; NF-kappa B; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Purinergic P2Y12; Thrombosis

2017
Effect of P2Y
    Thrombosis research, 2019, Volume: 173

    Topics: Adenosine Monophosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Fibrin Clot Lysis Time; Fibrinolysis; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis; Ticagrelor

2019
Cangrelor for the Rescue of Intra-Procedural Stent Thrombosis in Percutaneous Coronary Intervention.
    Cardiovascular revascularization medicine : including molecular interventions, 2019, Volume: 20, Issue:7

    Topics: Adenosine Monophosphate; Aged; Angioplasty, Balloon, Coronary; Coronary Artery Disease; Female; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Stents; Thrombosis; Treatment Outcome

2019
Expanding the Treatment of Calcified Lesions.
    Cardiovascular revascularization medicine : including molecular interventions, 2019, Volume: 20, Issue:7

    Topics: Adenosine Monophosphate; Atherectomy, Coronary; Humans; Percutaneous Coronary Intervention; Stents; Thrombosis

2019
Glutamate induces synthesis of thrombogenic peptides and extracellular vesicle release from human platelets.
    Scientific reports, 2019, 06-06, Volume: 9, Issue:1

    Topics: Adenosine Monophosphate; Blood Platelets; Calcium; Cell Adhesion; Cytoskeleton; Cytosol; Extracellular Vesicles; Glutamic Acid; Humans; Ion Channels; Mitochondria; Nervous System; Oxygen Consumption; Peptide Biosynthesis; Phenotype; Phosphorylation; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Protein Binding; Reactive Oxygen Species; Signal Transduction; Thrombosis

2019
The duel between dual antiplatelet therapies.
    The New England journal of medicine, 2013, Apr-04, Volume: 368, Issue:14

    Topics: Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Clopidogrel; Female; Humans; Male; Myocardial Ischemia; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2013
ACP Journal Club. Cangrelor reduced ischemic PCI complications more than clopidogrel without increasing severe bleeding.
    Annals of internal medicine, 2013, Jun-18, Volume: 158, Issue:12

    Topics: Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Female; Humans; Male; Myocardial Ischemia; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2013
Platelet inhibition with cangrelor during PCI.
    The New England journal of medicine, 2013, 07-25, Volume: 369, Issue:4

    Topics: Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Female; Humans; Male; Myocardial Ischemia; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2013
Platelet inhibition with cangrelor during PCI.
    The New England journal of medicine, 2013, 07-25, Volume: 369, Issue:4

    Topics: Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Female; Humans; Male; Myocardial Ischemia; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2013
Disbalance between mortality and non-fatal vascular events in the CHAMPION-PHOENIX trial: the cangrelor efficacy challenge.
    Thrombosis and haemostasis, 2014, Volume: 111, Issue:1

    Topics: Adenosine Monophosphate; Blood Platelets; Clopidogrel; Data Interpretation, Statistical; Humans; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Randomized Controlled Trials as Topic; Research Design; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2014
Protective mechanisms of adenosine 5'-monophosphate in platelet activation and thrombus formation.
    Thrombosis and haemostasis, 2014, Mar-03, Volume: 111, Issue:3

    Topics: Adenosine A2 Receptor Agonists; Adenosine Monophosphate; Animals; Blood Platelets; CD40 Ligand; Cells, Cultured; Crotalid Venoms; Cyclic Nucleotide Phosphodiesterases, Type 3; Disease Models, Animal; Humans; Lasers; Lectins, C-Type; Mesenteric Veins; Mice; Molecular Targeted Therapy; P-Selectin; Peptide Fragments; Photochemical Processes; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptor, Adenosine A2A; Rose Bengal; Stereoisomerism; Thrombosis; Triazines; Triazoles

2014
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:9

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arterial Occlusive Diseases; Blood Coagulation; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hydrolysis; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monocytes; Phenotype; Platelet Activation; Thrombosis; Time Factors; Transfection

2016
Antiplatelet therapy: cangrelor for ACS-lessons from the CHAMPION trials.
    Nature reviews. Cardiology, 2010, Volume: 7, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Blood Platelets; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Ticlopidine; Treatment Outcome

2010
Platelet inhibition with cangrelor.
    The New England journal of medicine, 2010, Mar-18, Volume: 362, Issue:11

    Topics: Adenosine Monophosphate; Administration, Oral; Angioplasty, Balloon, Coronary; Clopidogrel; Humans; Infusions, Intravenous; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2010
Enhanced platelet reactivity and thrombosis in Apoe-/- mice exposed to cigarette smoke is attenuated by P2Y12 antagonism.
    Thrombosis research, 2010, Volume: 126, Issue:4

    Topics: Adenosine Monophosphate; Animals; Apolipoproteins E; Blood Platelets; Chlorides; Female; Ferric Compounds; Fibrinogen; Gene Deletion; Mice; Mice, Inbred C57BL; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thrombosis; Tobacco Smoke Pollution

2010
SCH 602539, a protease-activated receptor-1 antagonist, inhibits thrombosis alone and in combination with cangrelor in a Folts model of arterial thrombosis in cynomolgus monkeys.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:11

    Topics: Adenosine Monophosphate; Animals; Disease Models, Animal; Drug Therapy, Combination; Fibrinolytic Agents; Macaca fascicularis; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptor, PAR-1; Thrombosis

2010
BF061, a novel antiplatelet and antithrombotic agent targeting P2Y₁₂ receptor and phosphodiesterase.
    Thrombosis and haemostasis, 2011, Volume: 106, Issue:6

    Topics: Adenosine; Adenosine Monophosphate; Animals; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Fibrinolytic Agents; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phosphoric Diester Hydrolases; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis

2011
Increased platelet activation and thrombosis in transgenic mice expressing constitutively active P2Y12.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:10

    Topics: Adenosine Monophosphate; Animals; Bleeding Time; Blood Platelets; Chlorides; Cyclic AMP; Disease Models, Animal; Drug Inverse Agonism; Ferric Compounds; Fibrinolytic Agents; Genotype; Mice; Mice, Transgenic; Phenotype; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thrombosis

2012
Blockade of the platelet P2Y12 receptor by AR-C69931MX sustains coronary artery recanalization and improves the myocardial tissue perfusion in a canine thrombosis model.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Feb-01, Volume: 23, Issue:2

    Topics: Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Animals; Bleeding Time; Blood Coagulation; Coronary Circulation; Coronary Restenosis; Coronary Stenosis; Disease Models, Animal; Dogs; Drug Combinations; Echocardiography; Female; Heparin; Infusions, Intravenous; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Tissue Plasminogen Activator

2003
Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Oct-01, Volume: 23, Issue:10

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Disease Models, Animal; Humans; Leukocytes; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; P-Selectin; Peptide Fragments; Phosphatidylserines; Plasma; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombin; Thrombosis

2003
Adenylic therapy and vascular disease; a preliminary report on the administration of muscle adenylic acid in vascular disease with special attention to the post-thrombotic and post-phlebitic syndromes of the lower extremities.
    Journal of the National Association of Chiropodists, 1956, Volume: 46, Issue:6

    Topics: Adenosine Monophosphate; Attention; Lower Extremity; Nucleotides; Peripheral Vascular Diseases; Thrombosis; Vascular Diseases

1956
Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation.
    The Journal of clinical investigation, 2004, Volume: 113, Issue:10

    Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Blood Platelets; Bone Marrow Transplantation; Gene Expression; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Phenotype; Thrombosis; Transplantation Immunology

2004
Dependence of platelet thrombus stability on sustained glycoprotein IIb/IIIa activation through adenosine 5'-diphosphate receptor stimulation and cyclic calcium signaling.
    Journal of the American College of Cardiology, 2006, Jan-03, Volume: 47, Issue:1

    Topics: Adenosine Monophosphate; Blood Platelets; Calcium Channel Blockers; Calcium Signaling; Collagen; Humans; In Vitro Techniques; Lanthanum; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Thrombosis; Tirofiban; Tyrosine

2006
Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Antibodies, Monoclonal; Aspirin; Atherosclerosis; Blood Coagulation Tests; Blood Platelets; Carotid Stenosis; Dose-Response Relationship, Drug; Hemorheology; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis; Time Factors; von Willebrand Factor

2007
NTPDase and 5'-nucleotidase activities in platelets of human pregnants with a normal or high risk for thrombosis.
    Molecular and cellular biochemistry, 2007, Volume: 304, Issue:1-2

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens, CD; Apyrase; Blood Platelets; Capillary Permeability; Cell Membrane Permeability; Female; Humans; L-Lactate Dehydrogenase; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Thrombosis

2007
Antagonists of the platelet P2T receptor: a novel approach to antithrombotic therapy.
    Journal of medicinal chemistry, 1999, Jan-28, Volume: 42, Issue:2

    Topics: Adenosine Monophosphate; Blood Platelets; Humans; Magnetic Resonance Spectroscopy; Membrane Proteins; Molecular Structure; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Spectrometry, Mass, Fast Atom Bombardment; Thrombosis

1999
Role of ADP receptor P2Y(12) in platelet adhesion and thrombus formation in flowing blood.
    Arteriosclerosis, thrombosis, and vascular biology, 2002, Apr-01, Volume: 22, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aged; Analysis of Variance; Blood Platelets; Humans; Male; Membrane Proteins; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis

2002
A membrane-bound enzyme in rabbit aorta capable of inhibiting adenosine-diphosphate-induced platelet aggregation.
    Lancet (London, England), 1977, Aug-13, Volume: 2, Issue:8033

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta; Apyrase; Cell Extracts; Cell Membrane; Phosphoric Monoester Hydrolases; Platelet Aggregation; Rabbits; Thrombosis

1977
The mechanism of thrombocytes aggregation by streptokinase and its influencing by drugs.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 52

    Topics: Adenosine Monophosphate; Aminobenzoates; Aminocaproates; Aniline Compounds; Antigen-Antibody Complex; Antistreptolysin; Benzyl Compounds; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Imidazoles; In Vitro Techniques; Phenylbutazone; Platelet Adhesiveness; Sodium Salicylate; Streptokinase; Thrombosis; Time Factors

1972