adenosine diphosphate has been researched along with Thrombosis in 477 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 182 (38.16) | 18.7374 |
| 1990's | 51 (10.69) | 18.2507 |
| 2000's | 111 (23.27) | 29.6817 |
| 2010's | 106 (22.22) | 24.3611 |
| 2020's | 27 (5.66) | 2.80 |
| Authors | Studies |
|---|---|
| Alber, M; Burns, JC; Grande Gutiérrez, N; Kahn, AM; Marsden, AL; Mathew, M; McCrindle, BW | 1 |
| Hoylaerts, MF; Nemmar, A | 1 |
| Böhm, A; Grammbauer, S; Greinacher, A; Hafkemeyer, A; Hasan, M; Jedlitschky, G; Moritz, E; Palankar, R; Rauch, BH; Tolksdorf, C; Tzvetkov, MV; Wolf, R | 1 |
| Cui, L; Fu, L; Li, B; Liu, H; Liu, Y; Yang, Y | 1 |
| Baltz, A; Chuprun, JK; Cooper, M; Koch, WJ; Ma, P; McKenzie, SE; Michael, JV; Stalker, TJ; Tomaiuolo, M; Yarman, Y; Zhao, X; Zhu, L | 1 |
| Bayhan, T; Eker, İ; Kaçar, D; Kurt, ZDÇ; Özbek, NY; Sönmez, Ç; Yarali, N | 1 |
| Hanumegowda, S; Kengaiah, J; Laxmaiah, RK; Manjappa, B; Martin, SS; Nandish, SKM; Ramachandraiah, C; Sannaningaiah, D; Shinde, M; Shivaiah, A; Srinivasa, C | 1 |
| Fang, Q; Peng, S; Wang, Y; Wu, J; Yang, Y; Zhang, X; Zhao, M | 1 |
| Alasadi, Y; Asgar, JA; Bliden, KP; Chaudhary, R; Duhan, S; Gill, H; Gurbel, PA; Kundan, P; Sharma, T; Singh, A; Tantry, US | 1 |
| Han, K; Huang, X; Ma, M; Sun, T; Yang, S; Zhao, Z; Zhou, Y | 1 |
| Cheung, SS; Hellsten, Y; Lundberg Slingsby, MH; Nørregaard, LB; Wickham, KA | 1 |
| de Groot, PG; de Laat, B; Heemskerk, JWM; Roest, M; Swieringa, F; Zou, J | 1 |
| Cheng, XD; Li, YJ; Wang, JH; Wang, L; Yang, B; Yang, X; Yu, NW; Zhang, J; Zhang, Q; Zhang, X | 1 |
| Chen, P; Chu, Q; Feng, X; Gong, S; Pan, Y; Qiu, P; Yang, S; Zhou, S | 1 |
| Baaten, CCFMJ; De Simone, I; Gibbins, JM; Heemskerk, JWM; Jones, CI; Ten Cate, H; van der Meijden, PEJ | 1 |
| Bergmeier, W; Blatt, TN; Clark, EG; Harden, TK; Kawano, T; Mackman, N; Murcia, S; Mwiza, JMN; Nicholas, RA; Paul, DS; Poe, KO; Schug, WJ | 1 |
| Coxon, FP; Jalal, MM; Mutch, NJ; Whyte, CS | 1 |
| Albadawi, DAI; Chaggar, V; Dash, PR; Patel, K; Patra, PH; Ravishankar, D; Salamah, M; Vaiyapuri, R; Vaiyapuri, S; Watson, KA; Williams, HF | 1 |
| Bryant, SC; Jaffe, AS; Karon, BS; Katzman, BM; Scott, RJ; Wockenfus, AM | 1 |
| Kanthi, Y; Knight, JS; Pinsky, DJ; Zuo, Y | 1 |
| Bennewitz, MF; Brzoska, T; Gladwin, MT; Neal, MD; Ragni, MV; Sundd, P; Tutuncuoglu, E; Vats, R; Watkins, SC | 1 |
| Bokemeyer, C; Fiehler, J; Frölich, AM; Haddad, M; Holst, B; Holstein, K; Janjetovic, S; Langer, F; Renné, T; Rolling, CC; Rolling, T; Tomada, J; Voigtländer, M | 1 |
| Groß, K; Jäckel, S; Jurk, K; Karwot, C; Kiouptsi, K; Pontarollo, G; Reinhardt, C; Wilms, E; Winterstein, J | 1 |
| Chen, Q; Huang, M; Wu, H; Wu, J; Xu, D; Zou, D | 1 |
| Abe, H; Endo, K; Miyata, S; Nogawa, M; Satake, M; Shiba, M | 1 |
| Alexander, RV; Askanase, AD; Conklin, J; Dervieux, T; Gartshteyn, Y; Geraldino-Pardilla, L; Kapoor, T; Khalili, L; Mor, A; Shimbo, D | 1 |
| Fan, D; Li, Q; Ma, LJ; Mao, YH; Tian, Z; Wan, JB; Ya, F; Yang, Y; Zhao, M; Zhao, Y; Zuo, X | 1 |
| Altié, A; Brouilly, N; Carminita, E; Crescence, L; Dubois, C; Panicot-Dubois, L | 1 |
| Duan, JA; Liu, L; Liu, P; Qian, DW; Su, SL; Tang, YP | 1 |
| Chauhan, G; Dash, D; Gautam, D; Krishnamurthy, S; Paliwal, P; Patne, SCU | 1 |
| Brunner, S; Hamm, W; Lackermair, K; Mehr, M; Rizas, K | 1 |
| Bhagirath, VC; Chan, NC; Dale, B; de Vries, TAC; Eikelboom, JW; Ginsberg, JS; Hirsh, J; Kruger, PC; Xu, K | 1 |
| Chernousova, LA; Denisova, TP; Dolotovskaya, PV; Furman, NV; Malinova, LI | 1 |
| Abe, H; Endo, K; Satake, M; Shiba, M | 1 |
| Chen, X; Li, D; Liu, J; Luo, X; Wang, K; Wang, Y; Wu, Y; Yang, Z; Zhang, L; Zhang, Y | 1 |
| Chou, DS; Chung, CL; Huang, SY; Kuo, JR; Lee, HC; Lin, KH; Lu, WJ; Sheu, JR | 1 |
| Canobbio, I; Catricalà, S; Consonni, A; Di Pasqua, LG; Guidetti, G; Manganaro, D; Torti, M | 1 |
| Kim, DS; Kim, HK; Lee, JJ; Myung, CS; Sung, YY; Yang, WK | 1 |
| Bhavanasi, D; Dangelmaier, C; Goldfinger, LE; Kim, S; Kunapuli, SP; Meng, S; Wang, H | 1 |
| Bass, M; Goggs, R; Harper, MT; Heesom, KJ; Mellor, H; Mundell, SJ; Poole, AW; Pope, RJ; Savage, JS; Williams, CM | 1 |
| Neubauer, M; Robier, C; Stettin, M | 1 |
| Gupta, N; Li, W; McIntyre, TM; Silverstein, RL; Willard, B | 1 |
| Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Kwon, SG; Lee, JH; Moon, JY; Oh, SB; Roh, DH; Yoon, SY | 1 |
| Grybauskas, P; Gustiene, O; Jankauskiene, L; Kupstyte, N; Lesauskaite, V; Skipskis, V; Tatarunas, V | 1 |
| Hers, I; Hunter, RW; Moore, SF | 1 |
| Dalén, M; Holm, M; Tornvall, P; van der Linden, J | 1 |
| Basić-Jukić, N; Kes, P; Martinović, Z; Pavlović, DB | 1 |
| Boldron, C; Bonnet-Lignon, S; Bono, F; Delesque-Touchard, N; Herbert, JM; Lassalle, G; Millet, L; Pflieger, AM; Salel, V; Savi, P | 1 |
| Badorc, A; Barré, G; Besse, A; Boldron, C; Bonnet-Lignon, S; Bono, F; Bordes, MF; Briot, C; Delesque, N; Dol, F; Fossey, V; Gau, B; Hérault, JP; Herbert, JM; Lassalle, G; Meneyrol, J; Millet, L; Nazare, M; Pflieger, AM; Rousseaux, T; Savi, P; Tissandié, S; Yvon, X; Zech, G | 1 |
| Abendschein, D; Broekman, MJ; Chen, R; Drosopoulos, JH; Jeong, SS; Marcus, AJ; Moeckel, D; Nguyen, A; Robson, SC; Sun, X | 1 |
| Balekar, N; Jain, DK; Rajput, MS | 1 |
| Akin, I; Yildiz, BS; Yildiz, M | 1 |
| Chang, YW; Cheng, JC; Cooper, JA; Huang, CL; Huang, DY; Lin, CC; Tsai, HJ; Tseng, CP | 1 |
| Harper, MT; Poole, AW; Walsh, TG | 1 |
| Hara, S; Kuwata, H; Murakami, M; Nakatani, Y; Ogawa, M; Rai, K; Suzuki, H; Takakura, Y; Yoda, E | 1 |
| Fischer von Mollard, G; Goggs, R; Golebiewska, EM; Harper, MT; Poole, AW; Savage, JS; Williams, CM | 1 |
| Abrams, CS; Brass, LF; Harper, DC; Kowalska, MA; Marks, MS; Meng, R; Poncz, M; Stalker, TJ; Wang, Y; Wu, J | 1 |
| Alarcón, M; Carrasco, G; Fuentes, E; Fuentes, M; Palomo, I | 1 |
| Flaumenhaft, R; Furie, B; Furie, BC; Gopal, S; Jasuja, R; Kim, SH; Sharda, A | 1 |
| Chen, M; Chen, Y; Kong, Y; Ming, X; Su, W; Su, X; Wang, Y; Ye, X | 1 |
| Chong, CM; Chu, IK; Cui, G; Guo, L; Hoi, MP; Lee, SM; Li, G; Quan, Q; Shan, L; Sun, Y; Wang, Y; Yu, P; Zhang, Z; Zhao, Y | 1 |
| Jandrot-Perrus, M; Jiang, P; Jondeau, G; Loyau, S; Ropers, J; Tchitchinadze, M | 1 |
| Li, JY; Liu, GR; Liu, XW; Ma, N; Mohamed, I; Yang, YJ; Zhang, JY | 1 |
| Goggs, R; Harper, MT; Offermanns, S; Poole, AW; Walsh, TG; Williams, CM | 1 |
| Fan, JY; Han, JY; Li, Q; Liu, YY; Lu, Y; Sun, K; Wang, CS | 1 |
| Gierlotka, M; Kaczmarski, J; Kim, MH; Kuliczkowski, W; Serebruany, V; Sliwka, J; Steter, D; Zembala, M; Zysko, D | 1 |
| Jakubowski, JA; Mizuno, M; Ohno, K; Sugidachi, A; Tomizawa, A | 2 |
| Barbieri, L; Bellomo, G; De Luca, G; Marino, P; Nardin, M; Pergolini, P; Rolla, R; Schaffer, A; Suryapranata, H; Verdoia, M | 1 |
| Chen, X; Chu, S; Fang, W; Fei, Y; He, G; Li, Y; Wang, D; Wang, S; Wu, Q; Yang, L | 1 |
| Ampofo, E; Eichler, H; Laschke, MW; Menger, MD; Müller, I; Später, T | 1 |
| Hu, H; Hu, M; Huang, Q; Liu, P; Liu, Y; Lu, L; Luo, D; Niu, Y; Wang, S; Yu, S; Yue, M; Zhou, Q | 1 |
| Feng, Q; Jiang, X; Liu, J; Ma, H; Peng, S; Tang, J; Wang, Y; Wu, J; Xu, W; Zhao, M; Zhu, H | 1 |
| Brass, LF; Diamond, SL; Muthard, RW; Stalker, TJ; Taliaferro, JP; Welsh, JD | 1 |
| Che, J; Guo, MM; Shen, S; Shi, XL; Wang, B; Zhang, GJ; Zhou, J | 1 |
| Choe, SY; Kim, JK; Kwon, G; Lee, J; Lim, YH; Park, J; Seo, Y | 1 |
| Adam, F; Berrou, E; Bobe, R; Bordet, JC; Bryckaert, M; Elaïb, Z; Prévost, N; Rosa, JP | 1 |
| Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG | 1 |
| Harris, SP; Ho, V; Li, RH; Stern, JA; Tablin, F | 1 |
| Huo, Z; Li, C; Wang, R; Wang, Z; Zhao, Z | 1 |
| Druey, KM; Hensch, NR; Karim, ZA; Khasawneh, FT; Tansey, MG | 1 |
| Brass, LF; Diamond, SL; Poventud-Fuentes, I; Sampietro, S; Stalker, TJ; Welsh, JD | 1 |
| Corscadden, K; Kaur, H; Othman, M; Ware, J | 1 |
| Chen, M; Cui, Q; Dai, K; He, S; Hu, R; Jiang, M; Li, Z; Ruan, C; Tian, J; Yan, R; Zhang, J; Zhang, Y; Zhao, L | 1 |
| Brakebusch, C; Chrostek-Grashoff, A; Elvers, M; May, F; Nieswandt, B; Pleines, I; Pozgajova, M; Strehl, A; Varga-Szabo, D | 1 |
| Bhattacharya, G; Bhattacharya, R; Bhattacharyya, M; Karmohapatra, SK; Sinha, AK | 1 |
| Dai, J; Houard, X; Louedec, L; Michel, JB; Philippe, M | 1 |
| Bai, L; Fang, W; Huo, J; Kong, Y; Xiong, J; Yunman, L | 1 |
| Crain, EJ; Hua, J; Rehfuss, R; Schumacher, WA; Watson, CA; Wong, PC | 1 |
| Lip, GY; Shantsila, E | 1 |
| Dellas, C; Ellrott, T; Faustin, V; Hasenfuss, G; Konstantinides, S; Lankeit, M; Riggert, J; Rohm, I; Schäfer, K | 1 |
| Abbate, R; Antoniucci, D; Antonucci, E; Buonamici, P; Fedi, S; Gensini, GF; Giusti, B; Gori, AM; Marcucci, R; Paniccia, R | 1 |
| Cosemans, JM; Gilio, K; Harper, MT; Heemskerk, JW; Karim, ZA; Konopatskaya, O; Molkentin, JD; Poole, AW; Verkade, P; Watson, SP; Whiteheart, SW; Zhao, Y | 1 |
| Ten Berg, JM; van Werkum, JW | 1 |
| Antonijevic, NM; Antovic, JP; Gligic, BLj; Marinkovic, JM; Obradovic, DV; Obradovic, SD; Ratkovic, NG; Subota, VS; Vojvodic, DV; Wallen, HN | 1 |
| Cheng, H; Dai, K; Fan, Y; Li, S; Shi, Q; Wang, Y; Wang, Z; Yan, R; Yuan, Y; Zhuang, F | 1 |
| Elghoroury, EA; Elshamaa, MF; Helmy, A | 1 |
| Chen, YS; Du, JR; He, Y; Wang, CY; Wang, J; Yu, DK; Zhang, L | 1 |
| Beaulieu, LM; Blair, PS; Costello, CE; Freedman, JE; McComb, ME; Perlman, DH; Rex, S; Vitseva, O | 1 |
| Chang, X; Fan, J; Jiang, D; Li, Z; Saito, M; Zhang, B; Zhang, Y | 1 |
| Berg, JM; Bouman, HJ; Elsenberg, EH; Hackeng, CM; van de Wal, RM; van Werkum, JW; Verheugt, FW; Zomer, AC | 1 |
| Braun, S; Kastrati, A; Mehilli, J; Morath, T; Schömig, A; Schulz, S; Sibbing, D; Stegherr, J; von Beckerath, N | 1 |
| Cattaneo, M | 1 |
| Braun, S; Kastrati, A; Mehilli, J; Morath, T; Schömig, A; Sibbing, D; Stegherr, J; Vogt, W; von Beckerath, N | 1 |
| Fukushima, K; Iwata, Y; Kitahara, H; Kobayashi, Y; Komuro, I; Kuroda, N; Kuwabara, Y; Nomura, F; Ooyama, M | 1 |
| Dai, K; Li, S; Liu, G; Shi, Q; Wang, Y; Wang, Z; Zhang, W | 1 |
| Hu, H; Huang, ZS; Jiang, L; Li, N; Zeng, CL; Zhu, LJ | 1 |
| Fan, HY; Fu, FH; Liu, K; Xu, H; Yang, MY; Zhang, AH | 1 |
| Abbate, R; Antonucci, E; Balzi, D; Giusti, B; Gori, AM; Maggini, N; Marcucci, R; Miranda, M; Paniccia, R; Prisco, D | 1 |
| Ashraf, MZ; Ma, Y; Podrez, EA | 1 |
| Neubauer, M; Neumeister, P; Quehenberger, F; Rainer, F; Robier, C; Sternad, H | 1 |
| Azumi, Y; Inatomi, S; Iwashita, M; Kikuchi, H; Kinugasa, S; Mori, K; Nakahata, N; Obara, Y; Oshima, Y | 1 |
| Concengco, C; Conley, P; Cornelissen, I; Coughlin, SR; David, T; Palmer, D; Pandey, A; Wilsbacher, L | 1 |
| Dicker, P; Foley, DP; Kenny, D; Mangiacapra, F; Mylotte, D; Peace, AJ; Tedesco, AT | 1 |
| Brandl, R; Dwivedi, S; Khandoga, AL; Pandey, D; Siess, W | 1 |
| Englezopoulos, CV; Katsouras, CS; Michalis, LK; Moussis, V; Papamichael, ND; Rousouli, KI; Roussa, VD; Stathopoulou, EM; Tellis, CC; Trypou, P; Tselepis, AD; Tsikaris, V | 1 |
| Grass, EH; Holstein, DM; Keller, C; Lechleiter, JD; Prajapati, SI; Walter, CA; Watts, LT; Zheng, W | 1 |
| Kim, S; Kunapuli, SP | 1 |
| Bartko, J; Firbas, C; Jilma, B; Schuetz, M; Schwameis, M; Siller-Matula, J; Spiel, AO; Weigl, M | 1 |
| Folts, JD; Karpen, CW; Morrison, DC; Papasian, CJ; Qureshi, AA; Qureshi, N | 1 |
| Hwang, JY; Hwang, SJ; Jeong, YH; Kim, IS; Kim, S; Koh, EH; Kwak, CH; Park, JR; Park, KS; Park, Y; Yun, SE | 1 |
| Bassler, N; Dezfouli, S; Hickey, MJ; Hohmann, JD; Jackson, S; Jia, F; Krajewski, S; Kurz, J; Nandurkar, H; Peter, K; Selan, C; Straub, A; Wendel, HP; Westein, E; Yuan, Y | 1 |
| Chen, WS; Li, TJ; Lu, WQ; Qiu, Y; Sun, LN; Tao, X | 1 |
| Coleman Anderson, L; Croce, K; Handy, DE; Jin, RC; Leopold, JA; Loscalzo, J; Mahoney, CE; Ottaviano, F; Tang, SS; Zhang, YY | 1 |
| Behr, T; Behr, W; Kuch, B; von Scheidt, W | 1 |
| Bliden, KP; Gurbel, PA; Jeong, YH; Tantry, US | 1 |
| Barrett, F; Gibson, KR; MacRury, SM; Megson, IL; Sharma, S; Winterburn, TJ | 1 |
| Bhatia, S; Medhi, B; Parmar, VS; Prasad, AK; Priya, N; Raj, HG; Singh, P | 1 |
| Abbate, R; Antoniucci, D; Buonamici, P; Gensini, GF; Giusti, B; Gori, AM; Marcucci, R; Migliorini, A; Parodi, G; Valenti, R | 1 |
| Babin, J; Bonnefoy, A; Bryckaert, M; Labarthe, B; Théroux, P | 1 |
| De Mey, JG; Feijge, MA; Heemskerk, JW; Kuijpers, MJ; Megens, RT; Nikookhesal, E; oude Egbrink, MG; van Giezen, JJ | 1 |
| Espinosa, EV; Khasawneh, FT; Murad, JP; Ting, HJ | 1 |
| Braun, A; Dietrich, A; Gupta, S; Mannhalter, C; May, F; Nieswandt, B; Pleines, I; Ramanathan, G; Thielmann, I; Varga-Szabo, D | 1 |
| Bai, L; Cen, J; Fang, W; Fu, J; Kong, Y; Li, Y; Xiong, J | 1 |
| Grgurevich, S; Jacoski, MV; Jennings, LK; Li, JS; Michelson, AD; Tyagi, A | 1 |
| Bhavaraju, K; Bynagari-Settipalli, YS; Jin, J; Kim, S; Kunapuli, SP; Lakhani, P; Rico, MC; Woulfe, D | 1 |
| Song, Q; Wang, S; Zhao, W | 1 |
| Brass, LF; Chatterjee, MS; Colace, TV; Diamond, SL; Flamm, MH; Jaeger, D; Jing, H; Sinno, T; Zhou, S | 1 |
| Bampalis, VG; Brantl, SA; Siess, W | 1 |
| Bruno, V; Freynhofer, MK; Huber, K; Wojta, J | 1 |
| Ding, Z; Du, H; Liu, G; Pan, C; Wei, X; Ye, J; Zhang, S; Zhang, Y | 1 |
| Araki, M; Ichihara, K; Mimura, Y; Nogaki, H; Okano, K | 1 |
| Xie, ML; Xue, J; Zhang, HQ; Zhang, KP; Zhu, LJ | 1 |
| Jackson, DE; Moheimani, F | 1 |
| Diamond, SL; Muthard, RW | 1 |
| Baeriswyl, G; Cook, S; Goy, JJ; Lehmann, S; Lehner, C; Oberhänsli, M; Puricel, S; Stauffer, JC; Togni, M | 1 |
| Barinov, ÈF; Sulaeva, ON | 1 |
| Harper, MT; Hers, I; Konopatskaya, O; Poole, AW; Savage, JS; Williams, CM | 1 |
| Gremmel, T; Kopp, CW; Koppensteiner, R; Panzer, S; Seidinger, D; Steiner, S | 1 |
| Chaikof, EL; Hagemeyer, CE; Haller, CA; Hohmann, JD; Krajewski, S; Nandurkar, HH; Peter, K; Selan, C; Straub, A; Wang, X | 1 |
| Becker, BF; Gloe, T; Klauss, V; Krötz, F; Pohl, U; Riexinger, T; Schiele, TM; Sohn, HY; Theisen, K; Zahler, S | 1 |
| Dinsdale, D; Hoet, PH; Hoylaerts, MF; Nemery, B; Nemmar, A; Smith, T; Vermylen, J; Xu, H | 1 |
| Arnout, J; Boon, D; Hoylaerts, MF; Jankowski, M; Vermylen, J; Vreys, I; Wittevrongel, C | 1 |
| Ginsberg, MH; Riederer, MA; Steiner, B | 1 |
| Falk, E; Fuglsang, J; Møller, J; Ravn, HB; Stender, M; Zhou, J | 1 |
| Chudina, NA; Fesenko, OD; Murina, MA; Roshchupkin, DI; Sergienko, VI | 1 |
| Bonnefoy, A; Danloy, S; De Vos, R; Feijge, MA; Heemskerk, JW; Hoylaerts, MF; Kuijpers, MJ; Oury, C; Toth-Zsamboki, E; Vermylen, J; Vreys, I | 1 |
| Xu, D; Xu, S | 1 |
| Bergmeier, W; Brakebusch, C; Fässler, R; Heemskerk, JW; Kuijpers, MJ; Lindhout, T; Nieswandt, B; Offermanns, S; Schulte, V | 1 |
| Nurden, AT; Nurden, P | 2 |
| Baurand, A; Gachet, C | 1 |
| Nieswandt, B; Watson, SP | 1 |
| Dopheide, SM; Giuliano, S; Harper, IS; Jackson, SP; Kulkarni, S; Nesbitt, WS | 1 |
| Besta, F; Gawaz, M; Massberg, S; Müller, I; Schönig, A; Schulz, C | 1 |
| Hsiao, G; Lee, YM; Shen, MY; Sheu, JR; Yen, MH | 1 |
| Kunapuli, SP | 1 |
| Cazenave, JP; Freund, M; Gachet, C; Lenain, N; Léon, C | 1 |
| Peng, S; Tang, Z; Wang, Y; Xiao, Y; Zhao, M | 1 |
| Begaud, B; Boisseau, M; Garreau, C; Guerin, V; Molimard, M; Moore, N; Renard, M; Umar, A | 1 |
| Evans, RJ; Mahaut-Smith, MP; Pitt, SJ; Roberts, J; Rolf, MG; Vial, C | 1 |
| Cazenave, JP; Freund, M; Gachet, C; Leon, C; Ravanat, C | 1 |
| HOVIG, T | 1 |
| CHANDLER, AB; NORDOEY, A | 4 |
| CHAMBERS, DA; SALZMAN, EW | 1 |
| SILVER, MD; SILVER, MM; STEHBENS, WE | 1 |
| NORDOEY, A | 1 |
| Cazenave, JP; Gachet, C; Lanza, F; Wiesel, ML | 1 |
| Broekman, MJ; Drosopoulos, JH; Islam, N; Levi, R; Marcus, AJ; Pinsky, DJ; Sesti, C | 1 |
| Chen, G; Chen, S; Wang, WY; Wang, XM; Wei, Q; Xiong, YL | 1 |
| Arderiu, G; Escolar, G; Hernandez, MR; Pino, M; Serradell, M; Tonda, R | 1 |
| Bliden, KP; Gurbel, PA; Samara, WM | 1 |
| Alfonso, F; Angiolillo, DJ; Bañuelos, C; Bernardo, E; Escaned, J; Fernandez-Ortiz, A; Hernández-Antolín, R; Macaya, C; Moreno, R; Ramírez, C; Sabaté, M | 1 |
| Coppola, A; Coppola, L; Gombos, G; Grassia, A; Mordente, S; Peluso, G; Tondi, G | 1 |
| Angiolillo, DJ; Bernardo, E; Escaned, J; Fernandez-Ortiz, A; Hernández-Antolin, R; Macaya, C; Moreno, R; Pignatti, PF; Ramírez, C; Sabaté, M; Trabetti, E | 1 |
| Bergmeier, W; Cheng, G; Dole, VS; Piffath, CL; von Andrian, UH; Wagner, DD; Zhang, Y | 1 |
| Chen, CL; Chou, JD; Chou, KJ; Chung, HM; Fang, HC; Hwang, YY; Jan, CR; Lee, PT | 1 |
| Badimon, L; Salas, E; Segalés, E; Vilahur, G | 1 |
| Beythien, C; Gutensohn, K; Kühnl, P; Meinertz, T; Merten, M; Thiagarajan, P | 1 |
| Bliden, KP; Gurbel, PA; Samara, WM; Tantry, US | 1 |
| Aznar, J; Gabriel, F; Guiral, V; Labiós, M; Martínez, E; Martínez, M | 1 |
| Allen, D; Chen, P; Freedman, J; Gross, P; Leytin, V; Ni, H; Reheman, A; Yang, H | 1 |
| Baxi, SM; Gould, WR; Leadley, RJ; Peng, YW; Perrin, LA; Peterson, JT; Schroeder, R | 1 |
| Cattaneo, M; Cazenave, JP; Evans, R; Gachet, C; Hechler, B; Kassack, MU; Magnenat, S; Ullmann, H; Zighetti, ML | 1 |
| Haramaki, N; Ikeda, H; Imaizumi, T; Murohara, T; Yasukawa, H; Yokoyama, S | 1 |
| Mustard, JF; Packham, MA | 1 |
| Cattaneo, M; Gachet, C; Hechler, B | 1 |
| Gachet, C; Hechler, B | 1 |
| Herbert, JM; Savi, P | 1 |
| Asai, F; Jakubowski, JA; Niitsu, Y; Sugidachi, A | 1 |
| Humphries, RG; van Giezen, JJ | 1 |
| Broekman, MJ; Drosopoulos, JH; Islam, N; Levi, R; Marcus, AJ; Olson, KE; Pinsky, DJ | 1 |
| Czekay, RP; Dellas, C; Giandomenico, G; Koschnick, S; Loskutoff, DJ | 1 |
| Feijge, MA; Giesen, PL; Heemskerk, JW; Huijberts, M; van der Meijden, PE; van Raak, LP | 1 |
| Moliterno, DJ; Steinhubl, SR | 1 |
| Hornstra, G; Mensink, RP; Thijssen, MA | 1 |
| Hayashi, K; Kawasaki, T; Miyata, K; Moritani, Y; Saito, T; Takasaki, J; Taniguchi, M; Uchida, W; Uemura, T | 1 |
| Atar, D; Defranco, A; Mahmud, E; Malinin, A; Pokov, A; Schwartz, D; Schwartz, K; Serebruany, V; Spergling, M | 1 |
| Isobe, M; Kasuya, N; Kishi, Y; Numano, F; Yoshida, M | 1 |
| Akkerman, JW; Cauwenberghs, S; Curvers, J; Feijge, MA; Hageman, G; Heemskerk, JW; Hoylaerts, M | 1 |
| Barnard, MR; Fox, ML; Frelinger, AL; Furman, MI; Li, Y; Linden, MD; Michelson, AD | 1 |
| Bi, L; Bi, W; Cai, J; Fischer, NO; Liu, S; Peng, S; Tok, JB; Wang, G | 1 |
| Kastrati, A; Schömig, A; Sibbing, D; von Beckerath, N; von Beckerath, O | 1 |
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| Adam, F; Berrou, E; Bryckaert, M; Jandrot-Perrus, M; Kauskot, A; Mazharian, A; Nurden, P; Roger, S | 1 |
| González-Alonso, J; Jalkanen, S; Mortensen, SP; Samburski, SS; Yegutkin, GG | 1 |
| Brandl, R; Deckmyn, H; Penz, SM; Reininger, AJ; Siess, W; Toth, O | 1 |
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| Hayashi, H; Ito, H; Nagamura, Y; Sudo, T; Toga, K; Yamada, Y | 1 |
| Kahn, NN; Karmohapatra, SK; Sinha, AK | 1 |
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| Barnard, MR; Fox, ML; Frelinger, AL; Furman, MI; Jakubowski, JA; Li, Y; Linden, MD; Michelson, AD; Sugidachi, A; Winters, KJ | 1 |
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| Born, GV | 11 |
| Cazenave, JP; Hemmendinger, S; Wiesel, ML | 1 |
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| Hornstra, G | 3 |
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| Kelton, JG | 1 |
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| Andries, R; Boichot-Lagente, E; Bourgain, RH; Decuyper, K; Paubert-Braquet, M; Shen, S | 1 |
| Badimon, JJ; Badimon, L; Chesebro, JH; Fuster, V; Weng, D | 1 |
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| Asai, F; Inoue, T; Koike, H; Ogawa, T; Sugidachi, A | 1 |
| Arruzazabala, ML; Carbajal, D; Más, R; Molina, V; Valdés, S | 1 |
| Badimon, JJ; Chesebro, JH; Fuster, V; Rauch, U; Reis, ED; Roqué, M | 1 |
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| Bernat, A; Herbert, JM; Lalé, A; Roque, C; Savi, P; Zamboni, G | 1 |
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| de Nully Brown, P; Hasselbalch, HC; Jensen, MK; Lund, BV; Nielsen, OJ | 1 |
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| Birk, AV; Broekman, MJ; Bubman, D; Drosopoulos, JH; Marcus, AJ; Robertson, HD; Szeto, HH | 1 |
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56 review(s) available for adenosine diphosphate and Thrombosis
| Article | Year |
|---|---|
Reversible Platelet Integrin αIIbβ3 Activation and Thrombus Instability.
Topics: Actomyosin; Adenosine Diphosphate; Animals; Blood Platelets; Fibrin; Fibrinogen; Mice; Phosphatidylinositols; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Proto-Oncogene Proteins c-akt; Thrombosis; von Willebrand Factor | 2022 |
Purinergic signaling: a potential therapeutic target for ischemic stroke.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Antigens, CD; Apyrase; Humans; Ischemic Stroke; Signal Transduction; Thrombosis | 2023 |
Importance of platelet aggregation in patients with end-stage renal disease.
Topics: Adenosine Diphosphate; Blood Platelet Disorders; Humans; Kidney Failure, Chronic; Kidney Transplantation; Platelet Aggregation; Renal Dialysis; Renal Replacement Therapy; Risk Factors; Thromboembolism; Thrombosis; Thromboxane A2 | 2013 |
Interaction between thienopyridines and proton pump inhibitors.
Topics: Adenosine Diphosphate; Drug Interactions; Humans; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Thienopyridines; Thrombosis | 2014 |
New P2Y(12) inhibitors.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thrombosis | 2010 |
P2Y12 receptor in platelet activation.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Fibrinolytic Agents; Humans; Membrane Proteins; Mice; Platelet Activation; Platelet Aggregation; Purinergic Agents; Receptors, Purinergic P2; Signal Transduction; Thrombosis | 2011 |
The role of platelets in athero-thrombotic events.
Topics: Adenosine Diphosphate; Animals; Atherosclerosis; Blood Platelets; Coronary Artery Disease; Coronary Thrombosis; Fibrinolytic Agents; Hemostasis; Humans; Plaque, Atherosclerotic; Platelet Activation; Platelet Aggregation Inhibitors; Thrombin; Thrombosis; Thromboxane A2 | 2012 |
P2Y12 receptor: platelet thrombus formation and medical interventions.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Gene Expression Regulation; Humans; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Signal Transduction; Thrombosis | 2012 |
[The role of purine receptors of thrombocytes in regulation of hemostasis].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Hemostasis; Humans; Receptors, Purinergic P2X1; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis | 2012 |
Advantages of fast-acting ADP receptor blockade in ischemic heart disease.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Drug Combinations; Humans; Myocardial Ischemia; Platelet Activation; Platelet Aggregation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Thrombosis; Tissue Plasminogen Activator | 2003 |
The P2Y(1) receptor as a target for new antithrombotic drugs: a review of the P2Y(1) antagonist MRS-2179.
Topics: Adenosine Diphosphate; Animals; Fibrinolytic Agents; Humans; Platelet Aggregation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y1; Thrombosis | 2003 |
Platelet-collagen interaction: is GPVI the central receptor?
Topics: Adenosine Diphosphate; Animals; Cloning, Molecular; Collagen; Hemostasis; Humans; Integrin alpha2beta1; Mice; Mice, Knockout; Models, Biological; Peptide Fragments; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein Isoforms; Receptors, Collagen; Signal Transduction; Thrombosis; Thromboxane A2 | 2003 |
P2 receptors and platelet activation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Hemostasis; Humans; Phospholipases A; Phospholipases A2; Platelet Activation; Platelet Aggregation; Receptors, Purinergic P2; Thrombosis | 2002 |
Heterologous cell-cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase-1).
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Aspirin; Cell Communication; Endothelial Cells; Hemostasis; Humans; Thrombosis | 2003 |
GPIIb/IIIa antagonists and other anti-integrins.
Topics: Abciximab; Adenosine Diphosphate; Administration, Oral; Animals; Antibodies, Monoclonal; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Integrins; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombasthenia; Thrombosis | 2003 |
Platelet aggregation and adenosine diphosphate/adenosine triphosphate receptors: a historical perspective.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Calcium Signaling; Clopidogrel; Cyclic AMP; Drug Resistance; Hemorrhagic Disorders; Hemostasis; Humans; Mice; Mice, Knockout; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Second Messenger Systems; Thrombosis; Ticlopidine | 2005 |
The P2 receptors in platelet function.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Blood Vessels; Cell Shape; Clopidogrel; Cytoplasmic Granules; Fibrinolytic Agents; Humans; Ion Transport; Membrane Proteins; Models, Biological; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor Cross-Talk; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Signal Transduction; Stress, Mechanical; Thrombosis; Ticlopidine | 2005 |
The platelet P2 receptors in thrombosis.
Topics: Adenosine Diphosphate; Animals; Blood Vessels; Clinical Trials as Topic; Clopidogrel; Fibrinolytic Agents; Hemorrhagic Disorders; Humans; Membrane Proteins; Mice; Mice, Knockout; Platelet Aggregation Inhibitors; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis; Ticlopidine | 2005 |
Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis.
Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Aspirin; Clinical Trials as Topic; Clopidogrel; Cohort Studies; Double-Blind Method; Drug Resistance; Fibrinolytic Agents; Forecasting; Humans; Membrane Proteins; Meta-Analysis as Topic; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Randomized Controlled Trials as Topic; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombophilia; Thrombosis; Ticlopidine | 2005 |
Pharmacology of CS-747 (prasugrel, LY640315), a novel, potent antiplatelet agent with in vivo P2Y12 receptor antagonist activity.
Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Biotransformation; Clinical Trials, Phase I as Topic; Clopidogrel; Collagen; Drug Evaluation, Preclinical; Drug Synergism; Fibrinolytic Agents; Hemostasis; Humans; Male; Membrane Proteins; Molecular Structure; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prodrugs; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thiophenes; Thrombin; Thrombosis; Ticlopidine | 2005 |
Preclinical and clinical studies with selective reversible direct P2Y12 antagonists.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Administration, Oral; Animals; Arterial Occlusive Diseases; Clinical Trials as Topic; Dogs; Double-Blind Method; Drug Evaluation, Preclinical; Female; Fibrinolytic Agents; Humans; Injections, Intravenous; Male; Membrane Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Rabbits; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Thrombosis; Ticagrelor | 2005 |
Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection.
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Aspirin; Blood Vessels; Cardiotonic Agents; Cells, Cultured; Cerebral Infarction; Coronary Disease; Drug Evaluation, Preclinical; Endothelial Cells; Endothelium, Vascular; Fibrinolytic Agents; Humans; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Neuroprotective Agents; Platelet Aggregation; Platelet Aggregation Inhibitors; Recombinant Proteins; Structure-Activity Relationship; Synaptosomes; Thrombosis | 2005 |
The role of the platelet in the pathogenesis of atherothrombosis.
Topics: Adenosine Diphosphate; Animals; Atherosclerosis; Blood Coagulation; Blood Platelets; CD40 Ligand; Collagen; Humans; Myocardial Ischemia; P-Selectin; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thrombosis | 2005 |
Variable platelet response to aspirin and clopidogrel in atherothrombotic disease.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Biomarkers; Biotransformation; Blood Coagulation Tests; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Interactions; Drug Resistance; Hemorrhage; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis; Thromboxane A2; Thromboxane B2; Ticlopidine; Treatment Failure | 2007 |
Platelet receptor redox regulation.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Blood Platelets; CD36 Antigens; Collagen; Cytoplasm; Dimerization; Heart Diseases; Hemostasis; Humans; NADPH Oxidases; Oxidation-Reduction; Platelet Aggregation; Protein Structure, Tertiary; Quercetin; Signal Transduction; Stroke; Superoxides; Thrombosis | 2008 |
P2 receptors, platelet function and pharmacological implications.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atherosclerosis; Blood Coagulation; Blood Platelets; Fibrinolytic Agents; Humans; Inflammation; Membrane Proteins; Mice; Mice, Knockout; Neovascularization, Physiologic; Platelet Activation; Polymorphism, Genetic; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Signal Transduction; Thrombosis | 2008 |
Current treatment for thrombotic diseases.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Clinical Trials as Topic; Cyclic AMP; Epinephrine; Fibrinolytic Agents; Heparin; Humans; Thrombin; Thrombosis; Vitamin K | 1984 |
Antiplatelet agents: rationale and results.
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Animals; Arachidonic Acids; Aspirin; Blood Platelets; Blood Vessel Prosthesis; Cerebrovascular Disorders; Collagen; Coronary Disease; Dipyridamole; Female; Heart Valve Prosthesis; Hemostasis; Humans; Intracranial Embolism and Thrombosis; Male; Myocardial Infarction; Platelet Adhesiveness; Platelet Aggregation; Sex Factors; Sulfinpyrazone; Thrombosis | 1983 |
Dextran and haemostasis. A review.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation Disorders; Blood Coagulation Factors; Dextrans; Fibrinolysis; Hemostasis; Heparin; Humans; Microcirculation; Platelet Adhesiveness; Platelet Aggregation; Thrombosis; Viscosity | 1982 |
Hemorheological influences on platelet thrombogenesis.
Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Carotid Artery Thrombosis; Coronary Disease; Hemodynamics; Humans; Intracranial Arteriosclerosis; Mice; Organ Specificity; Platelet Aggregation; Rheology; Thrombosis | 1983 |
Electrochemical properties of platelets: clinical and pharmacological applications.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Cell Membrane; Collagen; Electrochemistry; Electrophoresis; Humans; Hydrogen-Ion Concentration; Myocardial Infarction; Norepinephrine; Osmolar Concentration; Phosphates; Platelet Aggregation; Polymers; Risk; Serotonin; Sialic Acids; Sulfhydryl Compounds; Surface Properties; Thrombin; Thrombosis | 1983 |
Haemorheological aspects of thrombosis.
Topics: Adenosine Diphosphate; Arteries; Blood Flow Velocity; Blood Viscosity; Erythrocytes; Fibrinogen; Hematocrit; Humans; Myocardial Infarction; Platelet Aggregation; Thrombosis | 1980 |
Platelet behaviour and vascular disease.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; Humans; Imidazoles; Myocardial Infarction; Platelet Adhesiveness; Platelet Aggregation; Prognosis; Thrombosis; Vascular Diseases | 1980 |
[Recent studies on the mechanism and prevention of arterial thrombosis].
Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Blood Platelets; Erythrocytes; Hemodynamics; Humans; Hyperlipidemias; Lipoproteins; Lipoproteins, LDL; Platelet Adhesiveness; Thrombosis | 1982 |
Antiplatelet drugs. A comparative review.
Topics: Adenosine Diphosphate; Animals; Aspirin; Base Sequence; Blood Platelets; Consensus Sequence; Humans; Molecular Sequence Data; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thrombin; Thrombosis; Thromboxanes | 1995 |
A novel series of P2T purinoceptor antagonists: definition of the role of ADP in arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Fibrinolytic Agents; Humans; Purinergic P2 Receptor Antagonists; Thrombosis | 1995 |
Thrombosis and inflammation as multicellular processes: significance of cell-cell interactions.
Topics: Adenosine Diphosphate; Apyrase; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Eicosanoids; Endothelium, Vascular; HSP70 Heat-Shock Proteins; Humans; Inflammation; Nitric Oxide; Platelet Activation; Thrombosis | 1995 |
Clinical pharmacology of the adenosine diphosphate (ADP) receptor antagonist, clopidogrel.
Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Aspirin; Clopidogrel; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Signal Transduction; Thrombosis; Ticlopidine | 1998 |
Platelet surface physiology and its importance in pharmacotherapy design and development: the adenosine diphosphate receptor antagonists.
Topics: Adenosine Diphosphate; Blood Platelets; Drug Design; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Cell Surface; Receptors, Purinergic P2; Thrombosis | 2000 |
A new approach to antiplatelet therapy: inhibitor of GPIb/V/IX-vWF interaction.
Topics: Acetates; Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Arterial Occlusive Diseases; Collagen; Drug Evaluation, Preclinical; Epinephrine; Epitopes; Genetic Predisposition to Disease; Guinea Pigs; Hemorheology; Humans; Integrins; Liposomes; Macromolecular Substances; Myocardial Infarction; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Polymorphism, Genetic; Receptors, Collagen; Recombinant Fusion Proteins; Stress, Mechanical; Thrombosis; Tyrosine; von Willebrand Factor | 2000 |
Prostaglandins and thromboxanes: "middlemen" modulating platelet function in hemostasis and thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Arteriosclerosis; Blood Coagulation; Blood Platelets; Calcium; Cyclic AMP; Hemostasis; Humans; Prostaglandins; Prostaglandins G; Prostaglandins H; Rats; Thrombosis; Thromboxane A2; Thromboxanes | 1978 |
The hemostatic plug.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Blood Coagulation; Blood Coagulation Disorders; Blood Platelets; Collagen; Embolism; Hemostasis; Humans; Myeloproliferative Disorders; Platelet Adhesiveness; Platelet Aggregation; Skin; Thrombin; Thrombosis; Uremia; von Willebrand Diseases; Wiskott-Aldrich Syndrome | 1977 |
Contribution of platelets to thrombus formation.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Calcium; Collagen; Disease Models, Animal; Endothelium; Epinephrine; Humans; Platelet Aggregation; Serotonin; Thrombin; Thrombosis | 1978 |
[Longitudinal study of platelet function in infantile cortical hyperostosis].
Topics: Adenosine Diphosphate; Adrenal Cortex Hormones; Blood Cell Count; Blood Platelet Disorders; Blood Platelets; Epinephrine; Humans; Hyperostosis, Cortical, Congenital; Longitudinal Studies; Platelet Adhesiveness; Platelet Aggregation; Thrombosis | 1978 |
Platelet physiology and abnormalities of platelet function (second of two parts).
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Collagen; Factor VIII; Hemorrhagic Disorders; Humans; Molecular Weight; Platelet Adhesiveness; Platelet Aggregation; Platelet Factor 3; Purpura, Thrombocytopenic; Sialic Acids; Terminology as Topic; Thrombosis; von Willebrand Diseases | 1975 |
ADP induced blood platelet activation: a review.
Topics: Adenosine Diphosphate; Humans; Platelet Activation; Platelet Aggregation; Receptors, Purinergic; Species Specificity; Thrombosis | 1991 |
[The role of erythrocytes in the pathogenesis of functional disorders of blood platelets in patients with ischemic heart disease and the possibilities of their pharmacological correction].
Topics: Adenosine Diphosphate; Coronary Disease; Erythrocytes; Humans; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis | 1990 |
Physiological and pathological involvements of platelets.
Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Blood Flow Velocity; Blood Platelets; Cell Adhesion; Creatine Kinase; Hemostasis; Humans; Phosphocreatine; Phosphoenolpyruvate; Platelet Aggregation; Platelet Count; Thrombosis | 1985 |
Adenosine diphosphate as a mediator of platelet aggregation in vivo.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arterioles; Arteriosclerosis; Blood Platelets; Creatine Kinase; Hemorrhage; Hemostasis; Humans; Phosphocreatine; Platelet Adhesiveness; Platelet Aggregation; Thrombosis; Venules | 1985 |
Cyclic AMP and platelet function.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Biogenic Amines; Blood Coagulation; Blood Platelets; Cyclic AMP; Hemostasis; Humans; Platelet Adhesiveness; Prostaglandins; Serotonin; Thrombosis | 1972 |
Platelets and thrombogenesis--current concepts.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Coagulation; Blood Platelets; Clot Retraction; Cyclic AMP; Dipyridamole; Hemostasis; Humans; Platelet Adhesiveness; Thromboembolism; Thrombosis | 1972 |
[Aggregation inhibitors. The inhibition of platelet function by means of chemical substances].
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Aspirin; Blood Proteins; Calcium; Collagen; Dipyridamole; Epinephrine; Humans; Molecular Conformation; Phenothiazines; Phosphoric Diester Hydrolases; Platelet Adhesiveness; Platelet Aggregation; Sympatholytics; Thrombin; Thrombosis | 1973 |
The role of platelets in arterial and venous thrombosis.
Topics: Adenosine Diphosphate; Arteriosclerosis; Basement Membrane; Blood Coagulation; Blood Coagulation Factors; Blood Flow Velocity; Blood Platelets; Collagen; Fibrin; Fibrinolysis; Humans; Platelet Adhesiveness; Thrombophlebitis; Thrombosis | 1972 |
Fibrinogen: requirement for platelet aggregation and adhesion.
Topics: Adenosine Diphosphate; Adsorption; Afibrinogenemia; Animals; Blood Platelets; Blood Proteins; Calcium; Fibrinogen; Glass; Hemostasis; Humans; In Vitro Techniques; Magnesium; Microscopy, Electron; Platelet Adhesiveness; Snakes; Species Specificity; Swine; Thrombin; Thrombosis; Venoms | 1972 |
Mechanism of platelet aggregation and release: their possible role in vascular injury.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Arteriosclerosis; Blood Coagulation; Blood Platelets; Blood Proteins; Blood Vessels; Collagen; Disseminated Intravascular Coagulation; Fibrin; Fibrinogen; Glass; Graft Rejection; Hemostasis; Humans; Ischemia; Kidney Transplantation; Platelet Adhesiveness; Platelet Aggregation; Thrombosis; Transplantation, Homologous | 1973 |
Mechanisms of thrombosis.
Topics: Adenosine Diphosphate; Animals; Antigen-Antibody Complex; Arteriosclerosis; Blood Coagulation; Blood Coagulation Disorders; Blood Flow Velocity; Blood Platelets; Cell Membrane; Collagen; Coronary Disease; Cytoplasmic Granules; Factor VII; Factor XII; Fibrin; Fibrinolysis; Humans; Microscopy, Electron; Microtubules; Platelet Adhesiveness; Rabbits; Serotonin; Thrombosis | 1971 |
27 trial(s) available for adenosine diphosphate and Thrombosis
| Article | Year |
|---|---|
In Vitro Reversal of the Anti-Aggregant Effect of Ticagrelor Using Untreated Platelets.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Blood Platelets; Cells, Cultured; Female; Healthy Volunteers; Hemorrhage; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Transfusion; Platelet-Rich Plasma; Risk; Thrombosis; Ticagrelor; Young Adult | 2018 |
Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Horses; Humans; Immobilized Proteins; Integrin alpha2beta1; Losartan; Marfan Syndrome; Peptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Protein Multimerization; Receptors, Thrombin; Rheology; Thrombosis | 2015 |
Thrombotic events in high risk patients are predicted by evaluating different pathways of platelet function.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Likelihood Functions; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Risk Assessment; Risk Factors; ROC Curve; Thrombosis; Ticlopidine | 2008 |
Intradialytic and postdialytic platelet activation, increased platelet phosphatidylserine exposure and ultrastructural changes in platelets in children with chronic uremia.
Topics: Adenosine Diphosphate; Adolescent; Annexin A5; beta-Thromboglobulin; Blood Platelets; Child; Child, Preschool; Chronic Disease; Female; Humans; Male; Phosphatidylserines; Platelet Aggregation; Platelet Factor 4; Renal Dialysis; Thrombosis; Time Factors; Uremia | 2009 |
Clopidogrel response status assessed with Multiplate point-of-care analysis and the incidence and timing of stent thrombosis over six months following coronary stenting.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Blood Coagulation Tests; Clopidogrel; Drug Monitoring; Drug Resistance; Drug-Eluting Stents; Female; Germany; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Point-of-Care Systems; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; ROC Curve; Thrombosis; Ticlopidine; Time Factors; Treatment Failure | 2010 |
Increased platelet aggregation and in vivo platelet activation after granulocyte colony-stimulating factor administration. A randomised controlled trial.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Blood Platelets; Cardiovascular Diseases; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Neoplasms; P-Selectin; Peptide Fragments; Platelet Aggregation; Recombinant Proteins; Ristocetin; Sex Factors; Thrombosis | 2011 |
Platelet inhibition by adjunctive cilostazol versus high maintenance-dose clopidogrel in patients with acute myocardial infarction according to cytochrome P450 2C19 genotype.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Chi-Square Distribution; Cilostazol; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Genotype; Humans; Korea; Liver; Male; Middle Aged; Myocardial Infarction; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Regression Analysis; Risk Assessment; Risk Factors; Tetrazoles; Thrombosis; Ticlopidine; Treatment Outcome | 2011 |
Immunity to thrombotic events is achievable if we stop the guessing game: is this the major hidden message from GRAVITAS?
Topics: Adenosine Diphosphate; Drug-Eluting Stents; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Receptors, Purinergic P2Y12; Thrombosis | 2011 |
Pharmacodynamic effects of clopidogrel in pediatric cardiac patients: a comparative study of platelet aggregation response.
Topics: Adenosine Diphosphate; Adult; Arteries; Blood Platelets; Child, Preschool; Clopidogrel; Double-Blind Method; Female; Fetal Blood; Heart; Heart Diseases; Humans; Infant; Infant, Newborn; Male; Peptide Fragments; Placebos; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2012 |
A randomized comparison of platelet reactivity in patients after treatment with various commercial clopidogrel preparations: the CLO-CLO trial.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Clopidogrel; Cross-Over Studies; Drugs, Generic; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Patient Selection; Percutaneous Coronary Intervention; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Single-Blind Method; Stents; Therapeutic Equivalency; Thiophenes; Thrombosis; Ticlopidine; Treatment Outcome | 2012 |
Failure of clopidogrel to reduce platelet reactivity and activation following standard dosing in elective stenting: implications for thrombotic events and restenosis.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Clopidogrel; Coronary Restenosis; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Failure | 2004 |
Is a 300 mg clopidogrel loading dose sufficient to inhibit platelet function early after coronary stenting? A platelet function profile study.
Topics: Adenosine Diphosphate; Clopidogrel; Coronary Vessels; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Premedication; Stents; Thrombosis; Ticlopidine; von Willebrand Factor | 2004 |
The difference between clopidogrel responsiveness and posttreatment platelet reactivity.
Topics: Adenosine Diphosphate; Aged; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Predictive Value of Tests; Prognosis; Risk; Stents; Thrombosis; Ticlopidine | 2005 |
Stearic, oleic, and linoleic acids have comparable effects on markers of thrombotic tendency in healthy human subjects.
Topics: Adenosine Diphosphate; Adult; Aged; alpha-Linolenic Acid; Biomarkers; Collagen; Cross-Over Studies; Disease Susceptibility; Fatty Acids; Female; Humans; Male; Middle Aged; Oleic Acid; Phospholipids; Platelet Aggregation; Reference Values; Sex Characteristics; Stearic Acids; Thrombosis | 2005 |
Monitoring platelet inhibition after clopidogrel with the VerifyNow-P2Y12(R) rapid analyzer: the VERIfy Thrombosis risk ASsessment (VERITAS) study.
Topics: Adenosine Diphosphate; Adult; Aged; Alprostadil; Blood Platelets; Clopidogrel; Coronary Disease; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y1; Stents; Thrombosis; Ticlopidine | 2007 |
Diabetes mellitus and platelet function after administration of aspirin and a single 600 mg dose of clopidogrel.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Diabetes Complications; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Thrombin; Thrombosis; Ticlopidine | 2006 |
Platelet expression of CD40/CD40 ligand and its relation to inflammatory markers and adhesion molecules in patients with atrial fibrillation.
Topics: Adenosine Diphosphate; Atrial Fibrillation; Biomarkers; Blood Platelets; CD40 Antigens; CD40 Ligand; Cell Adhesion Molecules; Female; Follow-Up Studies; Gene Expression Regulation; Humans; Inflammation Mediators; Male; Middle Aged; Risk Factors; Thrombosis; Time Factors | 2007 |
Effects of selective cyclooxygenase isoform inhibition on systemic prostacyclin synthesis and on platelet function at rest and after exercise in healthy volunteers.
Topics: Adenosine Diphosphate; Adult; Aspirin; Atherosclerosis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Endothelium; Epoprostenol; Exercise; Humans; Isoenzymes; Lactones; Male; Platelet Activation; Rest; Risk Factors; Sulfones; Thrombosis; Thromboxane B2 | 2007 |
Therapeutic benefit of low-dose clopidogrel in patients undergoing carotid surgery is linked to variability in the platelet adenosine diphosphate response and patients' weight.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Body Weight; Clopidogrel; Endarterectomy, Carotid; Humans; Placebos; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Complications; Statistics as Topic; Thrombosis; Ticlopidine | 2007 |
The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Cell Adhesion Molecules; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Research Design; Risk Assessment; Risk Factors; ROC Curve; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2007 |
Functional impact of high clopidogrel maintenance dosing in patients undergoing elective percutaneous coronary interventions. Results of a randomized study.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Florida; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Research Design; Spain; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Residual prothrombotic status in low responder patients to clopidogrel identified by Vasodilator-Stimulated Phosphoprotein Phosphorylation (VASP) analysis?
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Aged, 80 and over; Biomarkers; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Drug Resistance; Female; Humans; Male; Microfilament Proteins; Middle Aged; Myocardial Ischemia; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Recurrence; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Current treatment for thrombotic diseases.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Clinical Trials as Topic; Cyclic AMP; Epinephrine; Fibrinolytic Agents; Heparin; Humans; Thrombin; Thrombosis; Vitamin K | 1984 |
Platelet activation during coronary angioplasty in humans.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Collagen; Contrast Media; Coronary Disease; Epinephrine; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Serotonin; Thrombosis | 1993 |
[Disorders of haemostasis in patients undergoing maintenance haemodialysis, with special reference to recurrent arteriovenous fistula thrombosis. Effects of dipyridamole (author's transl)].
Topics: Adenosine Diphosphate; Adult; Arteriovenous Shunt, Surgical; Blood Coagulation Disorders; Blood Platelet Disorders; Clinical Trials as Topic; Collagen; Dipyridamole; Factor V; Factor VIII; Female; Humans; Long-Term Care; Male; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Recurrence; Renal Dialysis; Thrombosis | 1976 |
Drugs affecting platelet behaviour.
Topics: Adenosine Diphosphate; Anticoagulants; Blood Coagulation; Blood Platelets; Clinical Trials as Topic; Humans; Platelet Adhesiveness; Platelet Aggregation; Thrombosis | 1976 |
Platelet function studies before and after operation and the effect of postoperative thrombosis.
Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Blood Cell Count; Blood Platelets; Chromatography; Collagen; Epinephrine; Female; Fibrinogen; Humans; Iodine Radioisotopes; Leg; Male; Middle Aged; Neoplasms; Placebos; Platelet Adhesiveness; Postoperative Complications; Radionuclide Imaging; Surgical Procedures, Operative; Thrombin; Thrombosis | 1974 |
395 other study(ies) available for adenosine diphosphate and Thrombosis
| Article | Year |
|---|---|
Computational modeling of blood component transport related to coronary artery thrombosis in Kawasaki disease.
Topics: Adenosine Diphosphate; Anticoagulants; Blood Coagulation; Blood Platelets; Computational Biology; Computer Simulation; Coronary Vessels; Humans; Mucocutaneous Lymph Node Syndrome; Platelet Activation; Platelet Aggregation; Thrombosis | 2021 |
Neutrophil Cathepsin G Enhances Thrombogenicity of Mildly Injured Arteries via ADP-Mediated Platelet Sensitization.
Topics: Adenosine Diphosphate; Animals; Arteries; Biomarkers; Blood Platelets; Cathepsin G; Disease Susceptibility; Humans; Mice; Mice, Knockout; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Platelet Activation; Platelet Aggregation; Protein Serine-Threonine Kinases; Thrombosis | 2022 |
Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets.
Topics: Adenosine Diphosphate; ATP-Binding Cassette Transporters; Blood Platelets; Calcium; Fluorescein-5-isothiocyanate; Humans; Integrins; Multidrug Resistance-Associated Proteins; Nucleotides, Cyclic; Signal Transduction; Thrombosis; Thromboxanes | 2022 |
A Collagen-Derived Oligopeptide from Salmo salar Collagen Hydrolysates Restrains Atherogenesis in ApoE
Topics: Adenosine Diphosphate; Animals; Atherosclerosis; Collagen; Endothelial Cells; Mice; Mice, Knockout, ApoE; Molecular Docking Simulation; Oligopeptides; Phosphatidylinositol 3-Kinases; Salmo salar; Thrombosis | 2022 |
GRK2 regulates ADP signaling in platelets via P2Y1 and P2Y12.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Hemostatics; Humans; Mice; Platelet Aggregation; Thrombosis | 2022 |
Evaluation of coagulation parameters and impact of transfusion on coagulation in patients with beta thalassemia major.
Topics: Adenosine Diphosphate; beta-Thalassemia; Blood Coagulation; Humans; Thrombophilia; Thrombosis | 2022 |
Sorghum Protein Extract Protects RBC from Sodium Nitrite-Induced Oxidative Stress and Exhibits Anticoagulant and Antiplatelet Activity.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Antioxidants; Blood Coagulation; Epinephrine; Hemorrhage; Mice; Oxidative Stress; Platelet Aggregation Inhibitors; Protein Carbonylation; Sodium Nitrite; Sorghum; Superoxide Dismutase; Thrombosis | 2021 |
(1R,3S)-THCCA-Asn: To show the discovery of selective inhibitor of thrombin by successfully combining virtual screening and biological assay.
Topics: Adenosine Diphosphate; Amino Acids; Animals; Arachidonic Acids; Biological Assay; Blood Platelets; Carboxylic Acids; Cattle; Mammals; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Thrombin; Thrombosis | 2022 |
Serial assessment of thrombogenicity and hemodynamics in patients with type II diabetes in a clinical research unit: Evidence for circadian variations in clot formation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 2; Humans; Thrombosis | 2022 |
Elevated serum C1q is an independent predictor of high residual platelet reactivity in CAD patients receiving clopidogrel therapy.
Topics: Adenosine; Adenosine Diphosphate; Clopidogrel; Complement C1q; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thrombosis; Ticagrelor; Ticlopidine | 2022 |
High-Intensity Exercise Training Improves Basal Platelet Prostacyclin Sensitivity and Potentiates the Response to Dual Anti-Platelet Therapy in Postmenopausal Women.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Cyclooxygenase 1; Diphosphates; Dual Anti-Platelet Therapy; Epoprostenol; Estrogens; Exercise; Female; Humans; Nitric Oxide; Peptides; Platelet Aggregation Inhibitors; Postmenopause; Receptors, Epoprostenol; Receptors, Thromboxane; Thrombin; Thrombosis; Thromboxanes | 2022 |
Hydroxyls on the B ring and gallic acyl are essential for catechins to restrain ADP-induced thrombosis.
Topics: Adenosine Diphosphate; Catechin; Humans; Platelet Aggregation; Tea; Thrombosis | 2023 |
Repeated platelet activation and the potential of previously activated platelets to contribute to thrombus formation.
Topics: Adenosine Diphosphate; Blood Platelets; Humans; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Receptors, Thrombin; Thrombin; Thrombosis | 2023 |
Loss of P2Y
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Hemostasis; Integrins; Mice; Platelet Aggregation; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis; Vascular System Injuries | 2023 |
Atorvastatin-mediated inhibition of prenylation of Rab27b and Rap1a in platelets attenuates their prothrombotic capacity and modulates clot structure.
Topics: Adenosine Diphosphate; Atorvastatin; Blood Platelets; Fibrinogen; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Prenylation; rab GTP-Binding Proteins; rap1 GTP-Binding Proteins; Thrombosis | 2023 |
Isorhapontigenin, a resveratrol analogue selectively inhibits ADP-stimulated platelet activation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Drug Evaluation, Preclinical; Female; Healthy Volunteers; Humans; Inhibitory Concentration 50; Male; Mice; Models, Animal; Molecular Docking Simulation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2Y12; Resveratrol; Signal Transduction; Stilbenes; Thrombosis | 2019 |
Estimating short- and long-term reference change values and index of individuality for tests of platelet function.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Biological Variation, Population; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Normal Distribution; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reference Values; Thrombosis | 2019 |
New (re)purpose for an old drug: purinergic modulation may extinguish the COVID-19 thromboinflammatory firestorm.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cytokine Release Syndrome; Dipyridamole; Drug Repositioning; Extracellular Traps; Humans; Pandemics; Phosphodiesterase Inhibitors; Pneumonia, Viral; Purinergic Agents; SARS-CoV-2; Thrombosis | 2020 |
Intravascular hemolysis triggers ADP-mediated generation of platelet-rich thrombi in precapillary pulmonary arterioles.
Topics: Adenosine Diphosphate; Anemia, Hemolytic; Animals; Arterioles; Blood Coagulation; Blood Platelets; Hemolysis; Humans; Lung; Mice; Pulmonary Artery; Receptors, Purinergic P2Y12; Thrombin; Thrombosis | 2020 |
Comparison of acetylsalicylic acid and clopidogrel non-responsiveness assessed by light transmittance aggregometry and PFA-100® in patients undergoing neuroendovascular procedures.
Topics: Adenosine Diphosphate; Aged; Alprostadil; Aspirin; Blood Coagulation Tests; Blood Platelets; Clopidogrel; Collagen; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Reproducibility of Results; Stents; Technology Assessment, Biomedical; Thrombosis; Time Factors | 2020 |
The Commensal Microbiota Enhances ADP-Triggered Integrin α
Topics: Adenosine Diphosphate; Animals; Arteries; Blood Platelets; Cell Adhesion; Collagen Type I; Female; Gastrointestinal Microbiome; Gene Expression; Germ-Free Life; Humans; Immunity, Innate; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Primary Cell Culture; Symbiosis; Thrombosis; Toll-Like Receptor 2; von Willebrand Factor | 2020 |
Prevention of platelet aggregation and arterial thrombosis using a modified Shenzhu Guanxin Formula.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Drugs, Chinese Herbal; Phosphatidylinositol 3-Kinases; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Thrombosis | 2020 |
In vitro thrombus formation and in vivo hemostasis mediated by platelets irradiated with bactericidal ultraviolet C from xenon flash under flow conditions.
Topics: Adenosine Diphosphate; Animals; Bacteria; Blood Platelets; Collagen; Fibrinogen; Hemostasis; Humans; Male; Mean Platelet Volume; Microscopy, Fluorescence; Models, Animal; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Plateletpheresis; Rabbits; Thrombosis; Ultraviolet Rays; Xenon | 2021 |
Platelet bound complement split product (PC4d) is a marker of platelet activation and arterial vascular events in Systemic Lupus Erythematosus.
Topics: Adenosine Diphosphate; Autoantibodies; Autoimmunity; Biomarkers; Blood Platelets; Complement Activation; Complement C4; Disease Susceptibility; Humans; Lupus Erythematosus, Systemic; Platelet Activation; Platelet Aggregation; Platelet Count; Thrombosis; Vascular Diseases | 2021 |
Ginsenosides Rb2 and Rd2 isolated from
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Flowers; Ginsenosides; Humans; Mice; Mice, Inbred C57BL; Panax notoginseng; Phosphatidylinositol 3-Kinases; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; Thrombosis | 2021 |
DNAse-dependent, NET-independent pathway of thrombus formation in vivo.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Deoxyribonuclease I; Extracellular Traps; Fibrin; Humans; Hydrolysis; Lasers; Leukocyte Elastase; Mice, Inbred C57BL; Models, Biological; Neutrophil Activation; Neutrophils; Platelet Activation; Protein-Arginine Deiminase Type 4; Thrombosis | 2021 |
[Effect of different fractions of Taohong Siwu decoction on ADP-induced platelet aggregation and thrombin activity].
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fibrinolytic Agents; Humans; Male; Mass Spectrometry; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thrombosis | 2016 |
Indole-3-carbinol improves neurobehavioral symptoms in a cerebral ischemic stroke model.
Topics: Adenosine Diphosphate; Animals; Behavior, Animal; Carrageenan; Cerebrovascular Circulation; Disease Models, Animal; Fibrinolytic Agents; Humans; Indoles; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Platelet Aggregation; Rats, Wistar; Thrombosis | 2018 |
Effect of Physical Exercise on Platelet Reactivity in Patients with Dual Antiplatelet Therapy.
Topics: Adenosine Diphosphate; Aspirin; Chromogranin A; Clopidogrel; Coronary Artery Disease; Electrocardiography; Exercise; Exercise Tolerance; Humans; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Thrombosis; Ticlopidine | 2018 |
[ADP-Induced Recalcified Blood Clotting Time as a Marker of Rethrombosis Risk and Effectiveness of Antiplatelet Therapy in Acute Coronary Syndrome].
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aspirin; Biomarkers; Humans; Male; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Thrombosis; Whole Blood Coagulation Time | 2018 |
Correlation between platelet thrombus formation on collagen-coated beads and platelet aggregation induced by ADP.
Topics: Adenosine Diphosphate; Collagen; Humans; Platelet Aggregation; Thrombosis | 2020 |
PDK1 regulates platelet activation and arterial thrombosis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arteries; Blood Platelets; Clot Retraction; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Thrombin; Thrombosis; Vasoconstrictor Agents | 2013 |
Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Gene Expression Regulation; Humans; Hydroxyl Radical; Mice; Mitogen-Activated Protein Kinases; Monoterpenes; Phospholipase C gamma; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Proto-Oncogene Proteins c-akt; Signal Transduction; Thrombin; Thrombosis; Tropolone | 2013 |
Immobilized amyloid Aβ peptides support platelet adhesion and activation.
Topics: Adenosine Diphosphate; Alzheimer Disease; Amyloid beta-Peptides; Blood Vessels; Cell Adhesion; Cell Membrane; Cerebrovascular Disorders; Collagen; Humans; Immobilized Proteins; Metalloproteases; Phosphatidylinositol 3-Kinases; Platelet Activation; Platelet Adhesiveness; Protein Kinase C; Thrombosis | 2013 |
Extract of Ulmus macrocarpa Hance prevents thrombus formation through antiplatelet activity.
Topics: Adenosine Diphosphate; Animals; Catechin; Chromatography, High Pressure Liquid; Collagen; Disease Models, Animal; Fibrinolytic Agents; Male; Plant Extracts; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thrombosis; Ulmus | 2013 |
RhoG protein regulates glycoprotein VI-Fc receptor γ-chain complex-mediated platelet activation and thrombus formation.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Carrier Proteins; Crotalid Venoms; Female; GTP Phosphohydrolases; Humans; Lectins, C-Type; Male; Membrane Glycoproteins; Mice; Mice, Knockout; Oligopeptides; Peptides; Phosphorylation; Platelet Aggregation; Platelet Membrane Glycoproteins; Polysaccharides; Protein Kinases; Receptors, Fc; rho GTP-Binding Proteins; Thionucleotides; Thrombosis | 2013 |
RhoG protein regulates platelet granule secretion and thrombus formation in mice.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Carrier Proteins; Female; GTP Phosphohydrolases; Hemostatics; Humans; Male; Mice; Mice, Knockout; Peptides; Platelet Activation; rho GTP-Binding Proteins; Secretory Vesicles; Thrombin; Thrombosis | 2013 |
Changes in response to antiaggregatory treatment in patients with myeloproliferative neoplasms: a sequential study using multiple electrode aggregometry.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Electrodes; Female; Hematologic Neoplasms; Humans; Male; Middle Aged; Myeloproliferative Disorders; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Thrombosis; Ticlopidine; Treatment Outcome | 2013 |
Proteasome proteolysis supports stimulated platelet function and thrombosis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell-Derived Microparticles; Chlorides; Cytoskeletal Proteins; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Filamins; Humans; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Transfusion; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Talin; Thrombin; Thrombosis; Time Factors; Ubiquitination | 2014 |
Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain.
Topics: Acids; Acrylamides; Adenosine Diphosphate; Animals; Benzophenanthridines; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Diterpenes; Hindlimb; Hot Temperature; Hyperalgesia; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Injections; Ion Channels; Ischemia; Pain; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Sodium Chloride; Thrombosis; Tissue Extracts; TRPV Cation Channels | 2014 |
The role of clinical parameters and of CYP2C19 G681 and CYP4F2 G1347A polymorphisms on platelet reactivity during dual antiplatelet therapy.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Thrombosis; Ticlopidine | 2014 |
Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Humans; Insulin-Like Growth Factor I; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Activation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Receptors, Purinergic P2Y12; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Thrombin; Thrombosis; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2014 |
Point-of-care testing of clopidogrel-mediated platelet inhibition and risk for cardiovascular events after coronary angiography with or without percutaneous coronary intervention.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Angiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Patient Readmission; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Point-of-Care Systems; Predictive Value of Tests; Prospective Studies; ROC Curve; Stents; Survival Analysis; Thrombosis; Ticlopidine | 2014 |
SAR216471, an alternative to the use of currently available P2Y₁₂ receptor inhibitors?
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Binding, Competitive; Biological Availability; Blood Platelets; CHO Cells; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hemorrhage; Humans; Indoles; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding; Purinergic P2Y Receptor Antagonists; Pyridazines; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction; Thionucleotides; Thrombosis; Transfection | 2014 |
N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Administration, Oral; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Indoles; Injections, Intravenous; Male; Models, Chemical; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y12; Thrombosis | 2014 |
Optimizing human apyrase to treat arterial thrombosis and limit reperfusion injury without increasing bleeding risk.
Topics: Adenosine Diphosphate; Animals; Apyrase; Clopidogrel; Coronary Circulation; Dogs; Fibrinolysis; Hemorrhage; Humans; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Piperazines; Platelet Aggregation; Prasugrel Hydrochloride; Risk Factors; Thiophenes; Thrombosis; Ticlopidine; Time Factors; Tissue Plasminogen Activator; Treatment Outcome; Vascular Patency | 2014 |
Inhibition of ADP-induced platelet aggregation and involvement of non-cellular blood chemical mediators are responsible for the antithrombotic potential of the fruits of Lagenaria siceraria.
Topics: Adenosine Diphosphate; Animals; Calcium; Cucurbitaceae; Female; Fibrinolytic Agents; Fruit; Goats; Kaempferols; Male; Mice; Phytotherapy; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Polyphenols; Pulmonary Embolism; Rats, Wistar; Thrombosis | 2014 |
Disabled-2 is required for efficient hemostasis and platelet activation by thrombin in mice.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Diphosphate; Animals; Disease Models, Animal; DNA-Binding Proteins; Hemostasis; Mice; Mice, Knockout; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Thrombin; Thrombosis; TOR Serine-Threonine Kinases | 2014 |
SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4.
Topics: Adenosine Diphosphate; Animals; Autocrine Communication; Blood Platelets; Calcium Signaling; Chemokine CXCL12; Collagen; Cyclic AMP; Horses; Humans; Platelet Activation; Platelet Aggregation; Receptors, CXCR4; Thrombosis; Thromboxane A2 | 2015 |
Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Collagen; Disease Susceptibility; Group VI Phospholipases A2; Mice; Mice, Inbred C57BL; Mice, Knockout; Phospholipids; Platelet Activation; Platelet Aggregation; Receptors, Purinergic P2Y; Serotonin; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Thrombosis; Thromboxane A2 | 2014 |
Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Digitonin; Exocytosis; Flow Cytometry; Hemostasis; Humans; Lysosomes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Platelet Activation; Qa-SNARE Proteins; Secretory Vesicles; SNARE Proteins; Thrombosis | 2015 |
Defective release of α granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models.
Topics: Adaptor Protein Complex 3; Adenosine Diphosphate; Animals; Blood Platelets; Carrier Proteins; Cell Degranulation; Disease Models, Animal; Guanine Nucleotide Exchange Factors; Hermanski-Pudlak Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Lectins; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Secretory Vesicles; SNARE Proteins; Thrombin; Thrombosis; Vesicular Transport Proteins | 2015 |
A novel role of Eruca sativa Mill. (rocket) extract: antiplatelet (NF-κB inhibition) and antithrombotic activities.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Brassicaceae; Chemokine CCL5; Disease Models, Animal; Fibrinolytic Agents; Humans; Interleukin-1beta; Mice; Mice, Inbred C57BL; NF-kappa B; P-Selectin; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Thromboxane B2; Transforming Growth Factor beta1 | 2014 |
Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Cell Degranulation; Disease Models, Animal; Endothelial Cells; Exocytosis; Female; Fibrin; Hermanski-Pudlak Syndrome; Human Umbilical Vein Endothelial Cells; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Aggregation; Protein Disulfide-Isomerases; RNA, Small Interfering; Thrombin; Thrombosis; Vesicular Transport Proteins | 2015 |
A Novel Direct Factor Xa Inhibitory Peptide with Anti-Platelet Aggregation Activity from Agkistrodon acutus Venom Hydrolysates.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Agkistrodon; Amino Acid Sequence; Animals; Anticoagulants; Blood Coagulation Tests; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Female; Hydrolysis; Male; Mice; Molecular Weight; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Snake Venoms; Thrombosis | 2015 |
Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Chlorides; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Fibrinolytic Agents; Gene Expression Regulation; Heme Oxygenase-1; Humans; Lactates; Microfilament Proteins; Models, Biological; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Disulfide-Isomerases; Proteomics; Rats; Thrombosis; Venous Thrombosis | 2015 |
Preventive Effect of Aspirin Eugenol Ester on Thrombosis in κ-Carrageenan-Induced Rat Tail Thrombosis Model.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Carrageenan; Disease Models, Animal; Erythrocyte Count; Erythrocytes; Eugenol; Fibrinogen; Hemoglobins; Male; Platelet Aggregation Inhibitors; Platelet Count; Prothrombin Time; Rats; Rats, Wistar; Thrombosis | 2015 |
Leukemia-associated Rho guanine-nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Cell Degranulation; Chlorides; Crosses, Genetic; Ferric Compounds; Gene Knockout Techniques; Mice; Mice, Knockout; Oligopeptides; Organ Specificity; Platelet Activation; Platelet Aggregation; rho GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors; rhoA GTP-Binding Protein; Thrombosis | 2015 |
Inhibitory effect of caffeic acid on ADP-induced thrombus formation and platelet activation involves mitogen-activated protein kinases.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Platelets; Caffeic Acids; Cell-Derived Microparticles; Cyclic AMP; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis | 2015 |
Low platelet activity predicts 30 days mortality in patients undergoing heart surgery.
Topics: Adenosine Diphosphate; Aged; Aortic Valve; Arachidonic Acid; Area Under Curve; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Erythrocyte Transfusion; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis; Thrombosis; Ticlopidine; Treatment Outcome | 2016 |
Prasugrel reduces ischaemic infarct volume and ameliorates neurological deficits in a non-human primate model of middle cerebral artery thrombosis.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Haplorhini; Hemorrhage; Infarction, Middle Cerebral Artery; Macaca fascicularis; Male; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Stroke; Thrombosis; Time Factors | 2015 |
Prevention of occlusive arterial thrombus formation by a single loading dose of prasugrel suppresses neointimal hyperplasia in mice.
Topics: Adenosine Diphosphate; Animals; Aorta; Arterial Occlusive Diseases; Arteries; Carotid Arteries; Chemokine CCL2; Chlorides; Ferric Compounds; Hyperplasia; Inflammation; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred C57BL; Neointima; Platelet Aggregation; Prasugrel Hydrochloride; Pyridines; RNA, Messenger; Thrombosis; Time Factors; Transforming Growth Factor beta1 | 2015 |
Advanced age and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Age Factors; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Female; Humans; Male; Middle Aged; Odds Ratio; Patient Discharge; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prevalence; Thrombosis; Ticagrelor; Ticlopidine; Time Factors | 2016 |
N2 extenuates experimental ischemic stroke through platelet aggregation inhibition.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arteriovenous Shunt, Surgical; Blood Coagulation; Brain; Brain Ischemia; Edema; Enzyme-Linked Immunosorbent Assay; Epoprostenol; Female; Imidazoles; Male; Maze Learning; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Stroke; Thrombosis; Thromboxane A2; Vanillic Acid | 2015 |
The Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic Activity.
Topics: Adenosine Diphosphate; Animals; Disease Models, Animal; Flow Cytometry; Indoles; Leukocytes; Mice; Mice, Inbred BALB C; Oligopeptides; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Tetradecanoylphorbol Acetate; Thrombosis | 2015 |
Misshapen/NIK-related kinase (MINK1) is involved in platelet function, hemostasis, and thrombus formation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chlorides; Ferric Compounds; MAP Kinase Signaling System; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Thrombosis | 2016 |
Aqueous extract of Rabdosia rubescens leaves: forming nanoparticles, targeting P-selectin, and inhibiting thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Coagulation; Blood Platelets; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Flow Cytometry; Hydroxybenzoates; Isodon; Magnetic Resonance Spectroscopy; Male; Nanoparticles; P-Selectin; Plant Extracts; Plant Leaves; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Rosmarinic Acid; Spectrometry, Mass, Electrospray Ionization; Thrombin; Thrombosis | 2015 |
A systems approach to hemostasis: 4. How hemostatic thrombi limit the loss of plasma-borne molecules from the microvasculature.
Topics: Adenosine Diphosphate; Animals; Blood Proteins; Fibrin; Hemostasis; Male; Mice; Mice, Inbred C57BL; Microvessels; Platelet Activation; Platelet Count; Thrombosis | 2016 |
Anti-platelet and anti-thrombosis characteristics of Z4A5, a novel selective platelet glycoprotein IIb/IIIa inhibitor, compared with eptifibatide under long-term infusion.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Dogs; Eptifibatide; Fibrinolytic Agents; In Vitro Techniques; Infusions, Intravenous; Male; Oligopeptides; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis | 2015 |
An ethanol extract of Ramulus mori improves blood circulation by inhibiting platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Carotid Arteries; Collagen; Ethanol; Fibrinolytic Agents; Male; Morus; Plant Extracts; Plant Stems; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Stilbenes; Thrombosis | 2016 |
Full activation of mouse platelets requires ADP secretion regulated by SERCA3 ATPase-dependent calcium stores.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Platelets; Calcium; Calcium Signaling; Gene Deletion; Hemorheology; Hemostasis; Horses; Mice, Inbred C57BL; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serotonin; Thrombosis | 2016 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arterial Occlusive Diseases; Blood Coagulation; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hydrolysis; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monocytes; Phenotype; Platelet Activation; Thrombosis; Time Factors; Transfection | 2016 |
Platelet Activation and Clopidogrel Effects on ADP-Induced Platelet Activation in Cats with or without the A31P Mutation in MYBPC3.
Topics: Adenosine Diphosphate; Animals; Carrier Proteins; Cat Diseases; Cats; Clopidogrel; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Mutation; Platelet Activation; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine | 2016 |
Characterization of the Anticoagulant and Antithrombotic Properties of the Sphingosine 1-Phosphate Mimetic FTY720.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arteriovenous Shunt, Surgical; Biomimetic Materials; Blood Platelets; Carotid Artery, Common; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Fingolimod Hydrochloride; Humans; Lysophospholipids; Male; Platelet Aggregation; Platelet Function Tests; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Thrombosis; Vena Cava, Inferior | 2017 |
RGS10 Negatively Regulates Platelet Activation and Thrombogenesis.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Platelets; Blotting, Western; Flow Cytometry; Hemostasis; Mice, Knockout; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, G-Protein-Coupled; RGS Proteins; Signal Transduction; Thrombosis | 2016 |
Hierarchical organization of the hemostatic response to penetrating injuries in the mouse macrovasculature.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arterioles; Blood Coagulation; Blood Platelets; Femoral Artery; Fibrin; Hemodynamics; Hemostasis; Intravital Microscopy; Mice; Mice, Inbred C57BL; Microcirculation; Platelet Activation; Platelet Aggregation Inhibitors; Signal Transduction; Thrombin; Thromboplastin; Thrombosis; Wounds, Penetrating | 2017 |
Thrombocytopathy leading to impaired in vivo haemostasis and thrombosis in platelet type von Willebrand disease.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Collagen; Disease Models, Animal; Genetic Predisposition to Disease; Hemostasis; Humans; Kinetics; Mice, Transgenic; Mutation; Phenotype; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Signal Transduction; Thrombin; Thrombosis; von Willebrand Diseases | 2017 |
Receptor-interacting protein kinase 3 promotes platelet activation and thrombosis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Disease Models, Animal; Gene Expression; Hemostasis; Humans; Mice; Mice, Knockout; Phosphatidylserines; Phosphorylation; Platelet Activation; Platelet Aggregation; Proto-Oncogene Proteins c-akt; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Thrombin; Thrombosis; Thromboxane A2 | 2017 |
Rac1 is essential for phospholipase C-gamma2 activation in platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Lectins, C-Type; Mice; Mice, Knockout; Phospholipase C gamma; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Poly I-C; rac1 GTP-Binding Protein; Thrombosis | 2009 |
The role of leucocytes in the acetyl salicylic acid (aspirin) induced nitric oxide synthesis in the production of interferon-alpha, a potent inhibitor of platelet aggregation and a thrombolytic agent.
Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Blood Platelets; Cyclic AMP; Cyclic GMP; Female; Fibrin; Fibrinolysis; Humans; Interferon-alpha; Leukocytes; Male; Mice; Middle Aged; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet-Rich Plasma; Thrombosis | 2009 |
Effect of blocking platelet activation with AZD6140 on development of abdominal aortic aneurysm in a rat aneurysmal model.
Topics: Adenosine; Adenosine Diphosphate; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Platelets; Disease Models, Animal; Disease Progression; Elastic Tissue; Guinea Pigs; Inflammation; Male; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Rats; Rats, Inbred Lew; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Ticagrelor; Time Factors; Transplantation, Heterologous | 2009 |
Anticoagulant and antithrombotic activity of a new peptide pENW (pGlu-Asn-Trp).
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Fibrinolysis; Fibrinolytic Agents; Hemorrhage; Injections, Intravenous; Mice; Mice, Inbred ICR; Microscopy, Electron, Transmission; Molecular Structure; Molecular Weight; Oligopeptides; Platelet Aggregation; Pyrrolidonecarboxylic Acid; Rabbits; Rats; Rats, Sprague-Dawley; Thrombosis; Whole Blood Coagulation Time | 2009 |
Clopidogrel versus prasugrel in rabbits. Effects on thrombosis, haemostasis, platelet function and response variability.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Binding, Competitive; Bleeding Time; Clopidogrel; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hemorrhage; Hemostasis; Male; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides; Thiophenes; Thrombosis; Ticlopidine | 2009 |
Predicting thrombotic events: creating a complex approach for a complex condition.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Reproducibility of Results; Risk Assessment; Risk Factors; ROC Curve; Thrombosis; Ticlopidine | 2008 |
Absence of leptin resistance in platelets from morbidly obese individuals may contribute to the increased thrombosis risk in obesity.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Body Mass Index; Case-Control Studies; Female; Humans; Janus Kinase 2; Leptin; Male; Obesity, Morbid; Phosphorylation; Platelet Aggregation; Platelet Function Tests; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Risk Assessment; Risk Factors; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Thrombosis; Up-Regulation | 2008 |
PKCalpha regulates platelet granule secretion and thrombus formation in mice.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cytoplasmic Granules; Integrins; Mice; Platelet Aggregation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Signal Transduction; Thrombosis | 2009 |
Platelet reactivity as a risk-factor for stent thrombosis: can this be one of the currently available appropriate methods to determine platelet reactivity?
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Flow Cytometry; Humans; Light; Platelet Aggregation; Stents; Thrombosis | 2008 |
Elevations in soluble CD40 ligand in patients with high platelet aggregability undergoing percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Cardiac Catheterization; CD40 Ligand; Female; Humans; Immunologic Factors; Male; Middle Aged; P-Selectin; Platelet Aggregation; Risk Factors; Thrombosis | 2009 |
Effects of microgravity and hypergravity on platelet functions.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Cytoskeleton; Hemorrhage; Hemostasis; Hindlimb Suspension; Humans; Hypergravity; Membrane Glycoproteins; Membrane Proteins; Mice; Models, Animal; P-Selectin; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Ristocetin; Space Flight; Thrombosis; Time Factors; von Willebrand Factor; Weightlessness Simulation | 2009 |
Z-ligustilide extracted from Radix Angelica Sinensis decreased platelet aggregation induced by ADP ex vivo and arterio-venous shunt thrombosis in vivo in rats.
Topics: 4-Butyrolactone; Adenosine Diphosphate; Angelica sinensis; Animals; Blood Coagulation; Depression, Chemical; Disease Models, Animal; Drugs, Chinese Herbal; Male; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thrombosis | 2009 |
Immune versus thrombotic stimulation of platelets differentially regulates signalling pathways, intracellular protein-protein interactions, and alpha-granule release.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Communication; Cytoplasmic Granules; Extracellular Signal-Regulated MAP Kinases; Factor XIIIa; Humans; Lipopeptides; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Activation; Proteomics; Proto-Oncogene Proteins c-akt; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thrombin; Thrombosis; Toll-Like Receptor 2 | 2009 |
Antithrombotic and fibrinolytic activities of methanolic extract of aged sorghum vinegar.
Topics: Acetic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Epinephrine; Fibrinolytic Agents; Male; Methanol; Phenols; Platelet Aggregation Inhibitors; Rabbits; Rats; Sorghum; Thrombosis | 2009 |
The influence of clinical characteristics, laboratory and inflammatory markers on 'high on-treatment platelet reactivity' as measured with different platelet function tests.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Platelets; Cells, Cultured; Clopidogrel; Drug Combinations; Female; Humans; Interleukin-6; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Sensitivity and Specificity; Thrombosis; Ticlopidine | 2009 |
Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Risk Assessment; Risk Factors; ROC Curve; Severity of Illness Index; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Antiplatelet effect of 50-mg maintenance dose of clopidogrel compared to 200 mg ticlopidine: a preliminary study.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Asian People; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Japan; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Mechanism of platelet functional changes and effects of anti-platelet agents on in vivo hemostasis under different gravity conditions.
Topics: Actin Cytoskeleton; Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Calcium; Chelating Agents; Contractile Proteins; Egtazic Acid; Filamins; Hemostasis; Humans; Hypergravity; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microfilament Proteins; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Protein Binding; Ristocetin; Thrombosis; Time Factors; Tirofiban; Tyrosine; Weightlessness Simulation | 2010 |
Salvianolic acid A inhibits platelet activation and arterial thrombosis via inhibition of phosphoinositide 3-kinase.
Topics: Adenosine Diphosphate; Adult; Animals; Arteries; Caffeic Acids; Collagen; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Lactates; Male; Mice; Phosphoinositide-3 Kinase Inhibitors; Platelet Activation; Platelet Aggregation; Signal Transduction; Thrombin; Thrombosis; Thromboxanes | 2010 |
Antiplatelet and antithrombotic activities of salvianolic acid A.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Caffeic Acids; Humans; Lactates; Male; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thrombin; Thrombosis | 2010 |
Comparison of methods for monitoring residual platelet reactivity after clopidogrel by point-of-care tests on whole blood in high-risk patients.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Blood Platelets; Coronary Artery Disease; Drug Monitoring; Female; Humans; Italy; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Receptors, Purinergic P2Y12; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Stents; Thrombosis; Treatment Outcome | 2010 |
Scavenger receptor BI modulates platelet reactivity and thrombosis in dyslipidemia.
Topics: Adenosine Diphosphate; Animals; Apolipoproteins E; Blood Platelets; Blotting, Western; Cholesterol; Crotalid Venoms; Dyslipidemias; Female; Flow Cytometry; Lectins, C-Type; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Microscopy, Electron; Oligopeptides; P-Selectin; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Scavenger Receptors, Class B; Thrombosis | 2010 |
Evaluation of platelet function and pharmacological platelet inhibition in patients with myeloproliferative disorders using multiple electrode aggregometry.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Aspirin; Austria; Case-Control Studies; Clopidogrel; Electrodes; Female; Humans; Linear Models; Male; Middle Aged; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polycythemia Vera; Predictive Value of Tests; Reproducibility of Results; Thrombocythemia, Essential; Thrombosis; Ticlopidine; Treatment Outcome; Young Adult | 2010 |
Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Basidiomycota; Biological Products; Blood Platelets; Collagen; Crotalid Venoms; Epinephrine; Humans; Indoles; Lectins, C-Type; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Signal Transduction; Thrombin; Thrombosis | 2010 |
Roles and interactions among protease-activated receptors and P2ry12 in hemostasis and thrombosis.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Diphosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Cell Cycle Proteins; Female; Hemostasis; Humans; In Vitro Techniques; Male; Mice; Mice, Knockout; Models, Biological; Receptors, Proteinase-Activated; Receptors, Purinergic P2Y12; Receptors, Thrombin; Signal Transduction; Thrombin; Thrombosis | 2010 |
Clopidogrel discontinuation and platelet reactivity following coronary stenting.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Epinephrine; Female; Humans; Ireland; Male; Middle Aged; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque.
Topics: Acid Phosphatase; Adenosine Diphosphate; Adenosine Triphosphate; Aminoquinolines; Blood Platelets; Collagen; Humans; Isoenzymes; P-Selectin; Plaque, Atherosclerotic; Platelet Aggregation; Platelet-Rich Plasma; Prostaglandin-Endoperoxide Synthases; Pyrimidines; rac1 GTP-Binding Protein; Signal Transduction; Tartrate-Resistant Acid Phosphatase; Thrombosis | 2010 |
A highly constrained cyclic (S,S)-CDC- peptide is a potent inhibitor of carotid artery thrombosis in rabbits.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Arachidonic Acid; Bleeding Time; Blood Coagulation; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Collagen; Disease Models, Animal; Electric Stimulation; Eptifibatide; Humans; Male; Molecular Sequence Data; Peptides; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombosis | 2011 |
Purinergic receptor stimulation reduces cytotoxic edema and brain infarcts in mouse induced by photothrombosis by energizing glial mitochondria.
Topics: Adenosine Diphosphate; Animals; Astrocytes; Brain Infarction; Cerebral Infarction; Edema; Inositol 1,4,5-Trisphosphate; Light; Male; Mice; Mitochondria; Neuroglia; Receptors, Purinergic; Receptors, Purinergic P2Y1; Thionucleotides; Thrombosis | 2010 |
Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries.
Topics: Adenosine Diphosphate; alpha-Tocopherol; Animals; Blood Platelets; Collagen; Coronary Stenosis; Dogs; Hematocrit; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Thrombosis; Tocotrienols | 2011 |
Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Antigens, CD; Apyrase; Blood Platelets; Fibrinogen; Fibrinolytic Agents; Humans; Hydrolysis; Hypothermia, Induced; Leukopenia; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; P-Selectin; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Recombinant Proteins; Thrombocytopenia; Thrombosis; von Willebrand Factor | 2011 |
Antiplatelet and antithrombotic activities of timosaponin B-II, an extract of Anemarrhena asphodeloides.
Topics: Adenosine Diphosphate; Anemarrhena; Animals; Anticoagulants; Blood Coagulation; Fibrin Fibrinogen Degradation Products; Fibrinolytic Agents; Partial Thromboplastin Time; Plasminogen; Platelet Aggregation; Platelet Aggregation Inhibitors; Prothrombin; Prothrombin Time; Rabbits; Saponins; Serum Globulins; Steroids; Thrombosis | 2011 |
Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Bleeding Time; Blood Platelets; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Genotype; Glutathione; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Mice; Mice, Knockout; P-Selectin; Platelet Aggregation; Reactive Oxygen Species; Risk Factors; Thrombosis | 2011 |
Optimizing of thienopyridine therapy by multiple electrode platelet aggregometry in clopidogrel low responders undergoing PCI.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Cerebrovascular Disorders; Cilostazol; Clopidogrel; Drug Monitoring; Drug Resistance; Drug Substitution; Electrodes; Female; Germany; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Predictive Value of Tests; Prospective Studies; Risk Assessment; Risk Factors; Stents; Tetrazoles; Thiophenes; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Therapeutic potential of N-acetylcysteine as an antiplatelet agent in patients with type-2 diabetes.
Topics: Acetylcysteine; Adenosine Diphosphate; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glutathione; Humans; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reactive Oxygen Species; Thrombin; Thrombosis | 2011 |
Characterization of a unique dihydropyrimidinone, ethyl 4-(4'-heptanoyloxyphenyl)-6-methyl-3,4-dihydropyrimidin-2-one-5-carboxylate, as an effective antithrombotic agent in a rat experimental model.
Topics: Adenosine Diphosphate; Animals; Aorta; Aspirin; Blood Platelets; Collagen; Cyclic GMP; Drug Synergism; Inflammation Mediators; Inhibitory Concentration 50; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Platelet Aggregation Inhibitors; Pyrimidinones; Rats; Rats, Sprague-Dawley; Thrombin; Thromboplastin; Thrombosis | 2011 |
High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angioplasty; Aspirin; Clopidogrel; Death; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Risk; Stents; Stroke; Thrombosis; Ticlopidine | 2011 |
Effects of P2Y(1) receptor antagonism on the reactivity of platelets from patients with stable coronary artery disease using aspirin and clopidogrel.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Thrombin; Thrombosis; Ticlopidine | 2012 |
Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y₁₂ antagonist ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blood Platelets; Clopidogrel; Cytoprotection; Platelet Activation; Protein Binding; Purinergic P2Y Receptor Antagonists; Rats; Rats, Inbred WKY; Thrombosis; Ticagrelor; Ticlopidine | 2011 |
Characterization of the in vivo antiplatelet activity of the antihypertensive agent losartan.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Antihypertensive Agents; Arachidonic Acid; Blood Coagulation; Carotid Artery Injuries; Losartan; Mice; Mice, Inbred C57BL; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Receptors, Thromboxane A2, Prostaglandin H2; Thrombosis | 2012 |
Defective diacylglycerol-induced Ca2+ entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; C-Reactive Protein; Calcium Channels; Calcium Signaling; Chlorides; Diglycerides; Disease Models, Animal; Ferric Compounds; Gene Expression Regulation; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; ORAI1 Protein; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; RNA, Messenger; Secretory Vesicles; Stromal Interaction Molecule 1; Thrombin; Thrombosis; Time Factors; TRPC Cation Channels; TRPC6 Cation Channel | 2012 |
New peptide pENW (pGlu-Asn-Trp) inhibits platelet activation by attenuating Akt phosphorylation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Fibrinolytic Agents; Male; Oligopeptides; P-Selectin; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Pyrrolidonecarboxylic Acid; Rabbits; Rats; Rats, Sprague-Dawley; Thrombosis | 2012 |
Protein kinase C isoform ε negatively regulates ADP-induced calcium mobilization and thromboxane generation in platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Disease Models, Animal; Humans; Intracellular Fluid; Mice; Platelet Aggregation; Platelet Count; Protein Kinase C-epsilon; Signal Transduction; Thrombosis; Thromboxanes | 2012 |
Total steroidal alkaloids from Veratrum patulum L. Inhibit platelet aggregation, thrombi formation and decrease bleeding time in rats.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Bleeding Time; Blood Coagulation; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Fibrinolytic Agents; Male; Phytotherapy; Plant Roots; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Rats; Rats, Sprague-Dawley; Rhizome; Thrombin; Thrombosis; Time Factors; Veratrum; Veratrum Alkaloids | 2012 |
Multiscale prediction of patient-specific platelet function under flow.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Calcium; Crotalid Venoms; HEK293 Cells; Humans; Lectins, C-Type; Male; Microfluidic Analytical Techniques; Models, Biological; Platelet Activating Factor; Platelet Function Tests; Predictive Value of Tests; Receptors, Thromboxane; Reference Values; Signal Transduction; Thrombosis; Vasoconstrictor Agents | 2012 |
Why and how to eliminate spontaneous platelet aggregation in blood measured by multiple electrode aggregometry.
Topics: Adenosine Diphosphate; Electrodes; Erythrocytes; Humans; Platelet Aggregation; Platelet Function Tests; Predictive Value of Tests; Reproducibility of Results; Specimen Handling; Thrombosis | 2012 |
BF066, a novel dual target antiplatelet agent without significant bleeding.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arterioles; Chlorides; Collagen; Ferric Compounds; Fibrinogen; Hemorrhage; Humans; Immobilized Proteins; Mice; Mice, Inbred C57BL; Oligopeptides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, Adenosine A2A; Thrombin; Thrombosis | 2012 |
Simultaneous assay of activated platelet count and platelet-activating capacity by P-selectin detection using K2-EDTA-treated whole blood for antiplatelet agents.
Topics: Adenosine Diphosphate; Anticoagulants; Aspirin; Blood Platelets; Citrates; Collagen; Drug Monitoring; Edetic Acid; Female; Flow Cytometry; Heparin; Humans; Male; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Reproducibility of Results; Sodium Citrate; Thrombosis; Time Factors; Young Adult | 2012 |
Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Aorta; Cerebral Infarction; Drugs, Chinese Herbal; Male; Middle Cerebral Artery; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thrombosis; Thromboxane B2; Venous Thrombosis | 2013 |
Blood clots are rapidly assembled hemodynamic sensors: flow arrest triggers intraluminal thrombus contraction.
Topics: Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Calcium; Cardiovascular Physiological Phenomena; Collagen; Equipment Design; Hemodynamics; Heterocyclic Compounds, 4 or More Rings; Humans; In Vitro Techniques; Microfluidic Analytical Techniques; Nonmuscle Myosin Type IIA; Regional Blood Flow; Signal Transduction; Thrombosis; Thromboxane A2 | 2012 |
Munc13-4 is critical for thrombosis through regulating release of ADP from platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Humans; Membrane Proteins; Thrombosis | 2013 |
Obesity is associated with poor response to clopidogrel and an increased susceptibility to protease activated receptor-1 mediated platelet activation.
Topics: Adenosine Diphosphate; Aged; Angioplasty; Blood Platelets; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Female; Humans; Male; Microfilament Proteins; Middle Aged; Obesity; P-Selectin; Phosphoproteins; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptor, PAR-1; Stents; Thrombosis; Ticlopidine; Translational Research, Biomedical | 2013 |
Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Blood Platelets; Drug Delivery Systems; Fibrinolytic Agents; Humans; Male; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Fusion Proteins; Single-Chain Antibodies; Thrombosis | 2013 |
NAD(P)H oxidase-dependent platelet superoxide anion release increases platelet recruitment.
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Drug Interactions; Humans; Kinetics; Models, Biological; NADPH Oxidases; Platelet Aggregation; Superoxide Dismutase; Superoxides; Thrombin; Thrombosis | 2002 |
Ultrafine particles affect experimental thrombosis in an in vivo hamster model.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Colloids; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Femoral Vein; Heart Diseases; Injections, Intravenous; Microscopy, Confocal; Microscopy, Electron; Particle Size; Particulate Matter; Platelet Aggregation; Polystyrenes; Silicones; Thrombosis | 2002 |
Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster.
Topics: Adenosine Diphosphate; Animals; Antibodies, Antiphospholipid; Antibodies, Monoclonal; beta 2-Glycoprotein I; Blood Platelets; Carotid Arteries; Cricetinae; Cross Reactions; Disease Models, Animal; Glycoproteins; Humans; Immunoglobulin Fab Fragments; Lupus Coagulation Inhibitor; Phospholipids; Photochemistry; Platelet Aggregation; Protein Binding; Thrombosis | 2003 |
Blockade of platelet GPIIB-IIIA (Integrin alphaII(b)beta(3)) in flowing human blood leads to passivation of prothrombotic surfaces.
Topics: Adenosine Diphosphate; Collagen; Fibrinogen; Hemorheology; Humans; Integrin alpha2beta1; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Thrombosis | 2002 |
Platelet activity and in vivo arterial thrombus formation in rats with mild hyperhomocysteinaemia.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Collagen; Homocysteine; Hyperhomocysteinemia; Male; Platelet Activation; Platelet Count; Rats; Rats, Wistar; Thrombosis | 2002 |
Antithrombotic activity of N,N-dichlorotaurine on mouse model of thrombosis in vivo.
Topics: Adenosine Diphosphate; Amino Acids; Animals; Chloramines; Disease Models, Animal; Fibrinolytic Agents; Kinetics; Male; Mice; Mice, Inbred CBA; Platelet Aggregation; Taurine; Thrombosis; Time Factors | 2002 |
Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype.
Topics: Adenosine Diphosphate; Animals; Blood Cell Count; Blood Platelets; Cell Size; Erythrocyte Count; Humans; Ion Channels; Kinetics; Megakaryocytes; Mice; Mice, Transgenic; Phenotype; Platelet Count; Receptors, Purinergic P2; Receptors, Purinergic P2X; Thrombin; Thrombosis | 2003 |
[The effects of starfish sterol on platelet aggregation].
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Male; Materia Medica; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Starfish; Sterols; Thrombosis | 2000 |
Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Collagen; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Integrin alpha2beta1; Mice; Mice, Knockout; Platelet Adhesiveness; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, IgG; Thrombosis; Thromboxane A2 | 2003 |
Intercellular calcium communication regulates platelet aggregation and thrombus growth.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Cell Communication; Chelating Agents; Cytosol; Egtazic Acid; Humans; Kinetics; Models, Biological; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Thrombosis; von Willebrand Factor | 2003 |
Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement.
Topics: Adenosine Diphosphate; Aged; Angina Pectoris; Clopidogrel; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prevalence; Prosthesis Implantation; Stents; Thrombosis; Ticlopidine | 2003 |
Antithrombotic effects of magnesium sulfate in in vivo experiments.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Pressure; Dose-Response Relationship, Drug; Fibrinolytic Agents; Fluorescein; Injections, Intravenous; Magnesium Sulfate; Mesenteric Arteries; Rats; Thrombosis | 2003 |
Inhibition of localized thrombosis in P2Y1-deficient mice and rodents treated with MRS2179, a P2Y1 receptor antagonist.
Topics: Adenosine Diphosphate; Animals; Clopidogrel; Disease Models, Animal; Drug Interactions; Mesenteric Arteries; Mice; Mice, Mutant Strains; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thromboplastin; Thrombosis; Ticlopidine; Vena Cava, Inferior | 2003 |
Anti-thrombotic activity of PDR, a newly synthesized L-Arg derivative, on three thrombosis models in rats.
Topics: Adenosine Diphosphate; Animals; Arginine; Arteriovenous Shunt, Surgical; Autacoids; Chlorides; Collagen; Electric Stimulation; Ferric Compounds; Fibrinolytic Agents; Male; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombin; Thrombosis | 2003 |
Effects of armagnac extracts on human platelet function in vitro and on rat arteriovenous shunt thrombosis in vivo.
Topics: Adenosine Diphosphate; Alcoholic Beverages; Animals; Arteriovenous Shunt, Surgical; Blood Platelets; Cell Adhesion; Collagen; Dose-Response Relationship, Drug; Freeze Drying; Humans; Hypoxanthine; Osmolar Concentration; Platelet Aggregation; Rats; Rats, Wistar; Thrombosis; Xanthine Oxidase | 2003 |
Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alternative Splicing; Blood Platelets; Calcium Signaling; Cell Line; Electrophysiology; Hemostasis; Humans; Membrane Proteins; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y12; Thrombosis; Transfection | 2003 |
Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Disease Models, Animal; Humans; Leukocytes; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; P-Selectin; Peptide Fragments; Phosphatidylserines; Plasma; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombin; Thrombosis | 2003 |
RELEASE OF A PLATELET-AGGREGATING SUBSTANCE (ADENOSINE DIPHOSPHATE) FROM RABBIT BLOOD PLATELETS INDUCED BY SALINE "EXTRACT" OF TENDONS.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Hemostasis; Heparin; Rabbits; Research; Tendons; Thrombosis; Tissue Extracts | 1963 |
PLATELET THROMBOSIS INDUCED BY ADENOSINE DIPHOSPHATE IN THE RAT.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Capillaries; Cardiovascular System; Injections, Intravenous; Pathology; Pulmonary Artery; Pulmonary Valve Insufficiency; Rats; Research; Respiratory Insufficiency; Thrombosis | 1964 |
ADENOSINE DIPHOSPHATE INDUCED THROMBOSIS IN HYPOTHYROID RATS.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Hypothyroidism; Pharmacology; Propylthiouracil; Pulmonary Embolism; Rats; Research; Thrombosis | 1964 |
THE INFLUENCE OF DIETARY FATS ON THE ADENOSINE DIPHOSPHATE INDUCED PLATELET THROMBOSIS IN THE RAT.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Dietary Fats; Leadership; Pharmacology; Rats; Research; Thrombosis | 1964 |
INHIBITION OF ADP-INDUCED PLATELET AGGREGATION BY SUBSTITUTED AMINO-ACIDS.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Alanine; Alkylation; Amino Acids; Aminocaproates; Aminocaproic Acid; Arginine; Blood Platelets; Butyrates; Glutamine; Glycine; Guanidines; Leucine; Pharmacology; Phenylalanine; Platelet Aggregation; Proline; Research; Thrombosis; Tyrosine | 1964 |
PLATELET REACTION TO ADENOSINE DIPHOSPHATE IN VIVO.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Blood Platelets; Leukocytes; Leukopenia; Pharmacology; Physiology; Rabbits; Research; Thrombosis | 1965 |
THE INFLUENCE OF HYPERCEPHALINAEMIA ON THE ADENOSINE DIPHOSPHATE INDUCED THROMBOSIS IN THE RAT.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Lagomorpha; Phosphatidylethanolamines; Pulmonary Embolism; Rabbits; Research; Thrombosis | 1965 |
THE INFLUENCE OF SATURATED FAT, CHOLESTEROL, CORN OIL AND LINSEED OIL ON THE ADP-INDUCED PLATELET ADHESIVENESS IN THE RAT.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Cholesterol; Corn Oil; Dietary Fats; Fatty Acids; Flax; Linseed Oil; Oils; Pharmacology; Platelet Adhesiveness; Rats; Research; Thrombosis; Zea mays | 1965 |
[Platelets and arterial thrombosis].
Topics: Adenosine Diphosphate; Angioplasty, Balloon; Anti-Bacterial Agents; Arterial Occlusive Diseases; Arteriosclerosis; Aspirin; Blood Platelets; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Thrombin; Thrombosis | 2003 |
TMVA, a novel GPIb-binding protein, significantly prevents platelet microthrombi formation and prolongs discordant cardiac xenograft survival.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Graft Survival; Guinea Pigs; Heart Transplantation; Lectins, C-Type; Male; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Rats; Rats, Wistar; Thrombosis; Transplantation, Heterologous; Viper Venoms; von Willebrand Factor | 2004 |
Evaluation of effects of rofecoxib on platelet function in an in vitro model of thrombosis with circulating human blood.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Cell Adhesion; Collagen; Cyclooxygenase Inhibitors; Endothelium; Humans; Lactones; Platelet Aggregation; Sulfones; Thrombosis | 2004 |
Effects of a moderate-intensity aerobic program on blood viscosity, platelet aggregation and fibrinolytic balance in young and middle-aged sedentary subjects.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Viscosity; Exercise; Female; Fibrinolysis; Hematocrit; Humans; Male; Middle Aged; Oxygen Consumption; Platelet Aggregation; Risk Factors; Thrombosis | 2004 |
807 C/T Polymorphism of the glycoprotein Ia gene and pharmacogenetic modulation of platelet response to dual antiplatelet treatment.
Topics: Adenosine Diphosphate; Aged; Clopidogrel; Collagen; Coronary Disease; Female; Humans; Integrin alpha2; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Stents; Thrombosis; Ticlopidine | 2004 |
Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo.
Topics: ADAM Proteins; ADAM17 Protein; Adenosine Diphosphate; Animals; Blood Platelets; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dipeptides; Hepatocytes; Humans; Hydroxamic Acids; L-Selectin; Male; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Platelet Transfusion; Radiation Chimera; Thrombin; Thrombosis | 2004 |
Platelet hyperreactivity in hemodialysis patients with frequently occluded vascular access.
Topics: Adenosine Diphosphate; Arachidonic Acid; Calcium; Catheters, Indwelling; Diabetes Mellitus; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Activation; Renal Dialysis; Thrombin; Thrombosis | 2004 |
Effects of a novel platelet nitric oxide donor (LA816), aspirin, clopidogrel, and combined therapy in inhibiting flow- and lesion-dependent thrombosis in the porcine ex vivo model.
Topics: Adenosine Diphosphate; Amino Acids; Animals; Aspirin; Benzoates; Blood Pressure; Clopidogrel; Collagen; Cyclooxygenase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; Guanylate Cyclase; Heart Rate; Hemorheology; Imidazoles; Membrane Proteins; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Quinoxalines; Random Allocation; Receptors, Purinergic P2Y12; rhoA GTP-Binding Protein; Sus scrofa; Thrombosis; Ticlopidine | 2004 |
Sulfatides activate platelets through P-selectin and enhance platelet and platelet-leukocyte aggregation.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Aggregation; Gene Expression Regulation; Humans; Leukocytes; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Sulfoglycosphingolipids; Thrombosis | 2005 |
Effect of atorvastatin upon platelet activation in hypercholesterolemia, evaluated by flow cytometry.
Topics: Adenosine Diphosphate; Adult; Aged; Atorvastatin; Blood Platelets; Case-Control Studies; Cholesterol; Cholesterol, LDL; Female; Flow Cytometry; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; In Vitro Techniques; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrroles; Risk Factors; Thrombin; Thrombosis | 2005 |
Vitronectin stabilizes thrombi and vessel occlusion but plays a dual role in platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chromatography, Gel; Lasers; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy; Muscles; Nitrogen; Plasma; Platelet Adhesiveness; Platelet Aggregation; Platelet Function Tests; Thrombin; Thrombosis; Vitronectin | 2005 |
Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.
Topics: Adenosine Diphosphate; Animals; Axl Receptor Tyrosine Kinase; Blood Platelets; c-Mer Tyrosine Kinase; Clopidogrel; Flow Cytometry; Humans; Intercellular Signaling Peptides and Proteins; Mice; Oligopeptides; Oncogene Proteins; Peptides; Platelet Activation; Platelet Aggregation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Saccharomyces cerevisiae Proteins; Signal Transduction; Thrombosis; Ticlopidine | 2005 |
Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfon
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Benzenesulfonates; Bleeding Time; Blood Platelets; Calcium; Collagen; Dose-Response Relationship, Drug; Epinephrine; Fibrinolytic Agents; Humans; In Vitro Techniques; Injections, Intravenous; Mice; Microscopy, Electron, Scanning; Oocytes; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Purinergic P2; Receptors, Purinergic P2X; Thromboembolism; Thrombosis; Xenopus laevis | 2005 |
Platelet P-selectin plays an important role in arterial thrombogenesis by forming large stable platelet-leukocyte aggregates.
Topics: Adenosine Diphosphate; Animals; Arteries; Cell Aggregation; Coronary Disease; Disease Models, Animal; Flow Cytometry; In Vitro Techniques; Leukocytes; Mice; Mice, Inbred C57BL; P-Selectin; Platelet Aggregation; Thrombosis | 2005 |
The leptin receptor system of human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Blotting, Western; Body Mass Index; Cell Line, Tumor; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Kinetics; Leptin; Ligands; Male; Microscopy, Electron, Transmission; Obesity; Platelet Activation; Platelet Aggregation; Protein Binding; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Thrombosis; Time Factors | 2005 |
Platelet P2Y12 receptors enhance signalling towards procoagulant activity and thrombin generation. A study with healthy subjects and patients at thrombotic risk.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Platelets; Calcium Signaling; Case-Control Studies; Clopidogrel; Diabetes Mellitus, Type 2; Humans; In Vitro Techniques; Membrane Proteins; Middle Aged; Phosphatidylserines; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stroke; Thrombin; Thrombosis; Ticlopidine | 2005 |
Biological properties of a specific Galpha q/11 inhibitor, YM-254890, on platelet functions and thrombus formation under high-shear stress.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cell Shape; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Femoral Artery; Fibrinogen; Fibrinolytic Agents; GTP-Binding Protein alpha Subunits, Gq-G11; Ligation; Macaca fascicularis; P-Selectin; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Regional Blood Flow; Stress, Mechanical; Thrombosis | 2006 |
P-selectin expression, but not GPIIb/IIIa activation, is enhanced in the inflammatory stage of Takayasu's arteritis.
Topics: Adenosine Diphosphate; Adult; Aged; Case-Control Studies; Female; Flow Cytometry; Humans; Inflammation; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Takayasu Arteritis; Thrombosis | 2006 |
Plasma ectonucleotidases prevent desensitization of purinergic receptors in stored platelets: importance for platelet activity during thrombus formation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Blood Preservation; Calcium Signaling; Humans; Plasma; Platelet Activation; Pyrophosphatases; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2X; Thrombosis | 2006 |
Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Clopidogrel; Coronary Artery Disease; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Resistance; Female; Flow Cytometry; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Signal Transduction; Thrombosis; Thromboxane B2; Ticlopidine; Time Factors; Treatment Refusal | 2006 |
Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates.
Topics: Adenosine Diphosphate; Animals; Carbolines; Drug Design; Fibrinolytic Agents; Free Radical Scavengers; Hydrogen; Molecular Structure; Oligopeptides; PC12 Cells; Phenol; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Thrombosis | 2006 |
Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Count; Cell Membrane; Hemorheology; Humans; Male; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Rats, Wistar; Stress, Mechanical; Surface Properties; Thrombosis | 2007 |
Protease-activating receptor-4 induces full platelet spreading on a fibrinogen matrix: involvement of ERK2 and p38 and Ca2+ mobilization.
Topics: Actins; Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Signaling; Cytoskeleton; Extracellular Matrix; Fibrinogen; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Myosin Light Chains; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Receptor, PAR-1; Receptors, Thrombin; Thrombin; Thrombosis | 2007 |
Intravascular ADP and soluble nucleotidases contribute to acute prothrombotic state during vigorous exercise in humans.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Exercise; Humans; Hydrolases; Male; Nucleotidases; P-Selectin; Pyrophosphatases; Risk Factors; Thrombosis; Vasodilation | 2007 |
Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Antibodies, Monoclonal; Aspirin; Atherosclerosis; Blood Coagulation Tests; Blood Platelets; Carotid Stenosis; Dose-Response Relationship, Drug; Hemorheology; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis; Time Factors; von Willebrand Factor | 2007 |
Genetic strain differences in platelet aggregation and thrombus formation of laboratory rats.
Topics: Adenosine Diphosphate; Animals; Arteriovenous Shunt, Surgical; Bleeding Time; Blood Platelets; Chlorides; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Genetic Variation; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Thrombin; Species Specificity; Thrombosis | 2007 |
The thrombolytic effect of aspirin in animal model.
Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Disease Models, Animal; Female; Fibrinolysis; Humans; Male; Middle Aged; Platelet-Rich Plasma; Thrombolytic Therapy; Thrombosis | 2007 |
NTPDase and 5'-nucleotidase activities in platelets of human pregnants with a normal or high risk for thrombosis.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens, CD; Apyrase; Blood Platelets; Capillary Permeability; Cell Membrane Permeability; Female; Humans; L-Lactate Dehydrogenase; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Thrombosis | 2007 |
The active metabolite of prasugrel inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: Influence of other blood cells, calcium, and aspirin.
Topics: Adenosine Diphosphate; Adult; Aspirin; Biomarkers; Blood Cells; Calcium; Cells, Cultured; Female; Humans; Inflammation; Kinetics; Male; Middle Aged; Piperazines; Platelet Activation; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Thiophenes; Thrombosis; Up-Regulation | 2007 |
[Modified platelet aggregation test in patients on ASA and/or clopidogrel].
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Clopidogrel; Collagen; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epinephrine; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Thrombosis; Ticlopidine | 2007 |
Platelet CD36 mediates interactions with endothelial cell-derived microparticles and contributes to thrombosis in mice.
Topics: Adenosine Diphosphate; Animals; Biomarkers; Blood Platelets; CD36 Antigens; Cell Membrane; Endothelial Cells; Humans; Immunoglobulin G; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylserines; Platelet Activation; Platelet Aggregation; Thrombosis | 2008 |
Platelets and blood vessels.
Topics: Adenosine Diphosphate; Arteriosclerosis; Blood Platelets; Blood Vessels; Hemostasis; Humans; Platelet Adhesiveness; Thrombosis | 1984 |
Aggregation of platelets in damaged vessels.
Topics: Adenosine Diphosphate; Animals; Arteries; Arteriosclerosis; Blood Platelets; Chlorpromazine; Collagen; Hemodynamics; Hemolysis; Hemostasis; Humans; Platelet Aggregation; Prostaglandins; Thrombosis | 1981 |
Platelet - vessel wall interaction: role of blood clotting.
Topics: Adenosine Diphosphate; Animals; Aorta; Blood Coagulation; Blood Platelets; Cod Liver Oil; Collagen; Endothelium; Epoprostenol; Factor VII; In Vitro Techniques; Rats; Thrombin; Thromboplastin; Thrombosis; Thromboxane A2 | 1981 |
[Behavior of platelet aggregation in the postoperative period after ditazol treatment].
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Blood Viscosity; Collagen; Epinephrine; Female; Humans; Male; Middle Aged; Oxazoles; Platelet Aggregation; Postoperative Complications; Pulmonary Embolism; Thromboembolism; Thrombosis | 1982 |
Experimental model of thrombus adherence to the vessel wall.
Topics: Adenosine Diphosphate; Animals; Aprotinin; Aspirin; Female; Hematocrit; Platelet Adhesiveness; Rats; Thrombosis | 1982 |
[Thrombosis and diabetic angiopathy].
Topics: Adenosine Diphosphate; beta-Thromboglobulin; Blood Coagulation Factors; Blood Platelets; Diabetic Angiopathies; Fibrinogen; Fibrinolysis; Humans; Platelet Aggregation; Thrombosis | 1982 |
[Prevention of thrombosis by thrombocyte inhibitors. 1. Cell regulation mechanisms and pharmacological modification].
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Cyclic AMP; Dextrans; Dipyridamole; Humans; Hydroxychloroquine; Indomethacin; Platelet Aggregation; Prostaglandins; Sulfinpyrazone; Thrombosis; Thromboxane A2 | 1980 |
Studies on aspirin derivatives with very little side effect. IV. Inhibitory effect of aspirin-isopropylantipyrine (AIA) on several experimental thromboses.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Antipyrine; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclic AMP; Epoprostenol; Malondialdehyde; Muscle Contraction; Rats; Thrombosis | 1983 |
[Blood flow and thrombogenesis. Correlation of blood platelets, blood coagulation factors and the vascular wall].
Topics: Adenosine Diphosphate; Arteriosclerosis; Blood Coagulation Factors; Blood Flow Velocity; Blood Platelets; Connective Tissue; Cyclic AMP; Endothelium; Fibrin; Humans; Ischemia; Platelet Adhesiveness; Platelet Aggregation; Rheology; Thrombosis | 1984 |
Inhibition of platelet aggregation by a new agent, 2,2'-dithiobis-(N-2-hydroxypropyl benzamide) (KF4939).
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Benzamides; Collagen; Dose-Response Relationship, Drug; Fibrinolytic Agents; Humans; In Vitro Techniques; Male; Mice; Papaverine; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Thrombin; Thrombocytopenia; Thrombosis; Thromboxane A2 | 1983 |
Inhibition of prostanoid-mediated platelet aggregation in vivo and in vitro by 3-hydroxymethyl-dibenzo(b,f)thiepin 5,5-dioxide (L-640,035).
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Dibenzothiepins; Electric Stimulation; Female; Guinea Pigs; Humans; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thrombosis; Thromboxane A2; Thromboxane B2; Thromboxanes | 1984 |
Platelets in atherogenesis and thrombogenesis.
Topics: Adenosine Diphosphate; Animals; Arteries; Blood Flow Velocity; Blood Platelets; Cricetinae; Humans; Platelet Aggregation; Thrombosis | 1984 |
The effect of cicletanide, a diuretic, on the platelet vessel wall interaction; its involvement in the arachidonic acid cascade.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Diuretics; Muscle, Smooth, Vascular; Pyridines; Rabbits; Thrombosis; Tranylcypromine | 1984 |
Vasoactive agents and production of thrombosis during intravascular coagulation 1--comparative effects of norepinephrine in thrombin and adenosine diphosphate (ADP) treated rabbits.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aminocaproic Acid; Animals; Aspirin; Blood Coagulation; Blood Coagulation Tests; Disseminated Intravascular Coagulation; Norepinephrine; Rabbits; Shwartzman Phenomenon; Thrombin; Thrombosis | 1984 |
The role of the platelets.
Topics: Adenosine Diphosphate; Angina Pectoris; Animals; Aspirin; Blood Platelets; Coronary Disease; Hemodynamics; Humans; Muscle, Smooth, Vascular; Platelet Aggregation; Thrombosis | 1984 |
A standardized 'in vivo' model for the study of experimental arterial thrombosis: description of a method.
Topics: Adenosine Diphosphate; Animals; Computers; Disease Models, Animal; Electric Injuries; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Rats; Rats, Inbred Strains; Thrombosis | 1984 |
In vivo study of platelet aggregation in rats.
Topics: Adenosine Diphosphate; Animals; Aspirin; Collagen; Diet; Dose-Response Relationship, Drug; Male; Methods; Platelet Aggregation; Platelet Count; Rats; Rats, Inbred Strains; Thiophenes; Thrombosis; Ticlopidine | 1984 |
Platelet and red cell involvement in mural thrombogenesis.
Topics: Adenosine Diphosphate; Blood Platelets; Erythrocytes; Glass; Hematocrit; Hemostasis; Humans; Platelet Adhesiveness; Rheology; Thrombosis | 1983 |
Antiplatelet drugs and thrombosis prevention: ticlopidine in perspective.
Topics: Adenosine Diphosphate; Aspirin; Bleeding Time; Blood Platelets; Fibrinolytic Agents; Humans; Thiophenes; Thrombosis; Ticlopidine | 1984 |
In vitro vs. ex vivo platelet deposition on polymer surfaces.
Topics: Adenosine Diphosphate; Animals; Arteriovenous Shunt, Surgical; Blood Platelets; Dogs; Macaca mulatta; Microscopy, Electron, Scanning; Plastics; Platelet Adhesiveness; Platelet Aggregation; Polyethylenes; Polyvinyl Chloride; Silicones; Thrombosis | 1984 |
A prospective method for thrombotic diseases using prostaglandin I2.
Topics: Adenosine Diphosphate; Aged; Epoprostenol; Humans; Intracranial Embolism and Thrombosis; Middle Aged; Platelet Aggregation; Prostaglandins; Thrombosis | 1982 |
Inhibition of arterial thrombosis and platelet function by nafazatrom.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Epoprostenol; Fibrinolytic Agents; In Vitro Techniques; Platelet Aggregation; Platelet Count; Prostaglandins F; Pyrazoles; Pyrazolones; Rabbits; Thrombosis | 1982 |
Effect of aspirin and aspirin lysinate on platelet function in smokers and non-smokers.
Topics: Adenosine Diphosphate; Adult; Aspirin; Bleeding Time; Blood Platelets; Humans; Lysine; Male; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Smoking; Thrombosis | 1980 |
Enhancement of arterial thromboformation by uric acid, a free radical scavenger.
Topics: Adenosine Diphosphate; Animals; Arterial Occlusive Diseases; Epoprostenol; Free Radicals; Photometry; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane A2; Tranylcypromine; Uric Acid | 1982 |
Influence of plasma fibronectin on the response to infusion of thrombin and adenosine diphosphate.
Topics: Adenosine Diphosphate; Animals; Antibodies; Blood Pressure; Fibrin Fibrinogen Degradation Products; Fibronectins; Infusions, Intra-Arterial; Male; Platelet Count; Rabbits; Rats; Rats, Inbred Strains; Sodium Chloride; Thrombin; Thrombosis | 1983 |
The interactions of lipids, platelets and endothelial cells in thrombogenesis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Blood Vessels; Coronary Disease; Diet; Disease Models, Animal; Endothelium; Fatty Acids; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Thrombosis; Thromboxane A2 | 1980 |
The functioning of blood platelets.
Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Blood Platelet Disorders; Blood Platelets; Hemostasis; Humans; Platelet Aggregation; Thrombin; Thrombosis; von Willebrand Diseases | 1980 |
Antithrombotic activity of a polydeoxyribonucleotidic substance extracted from mammalian organs: a possible link with prostacyclin.
Topics: Adenosine Diphosphate; Animals; Aorta; Arteries; Collagen; Colon; Coronary Vessels; Cricetinae; Electric Stimulation; Epoprostenol; Female; Fibrinolytic Agents; Gastric Mucosa; Iontophoresis; Male; Platelet Aggregation; Polydeoxyribonucleotides; Rabbits; Rats; Thrombophlebitis; Thrombosis | 1981 |
A quantitative method using continuous recording of platelet thrombus size in hamster cheek pouch.
Topics: Adenosine Diphosphate; Animals; Cheek; Cricetinae; Dose-Response Relationship, Drug; Electric Stimulation; Epoprostenol; Light; Male; Mesocricetus; Platelet Aggregation; Prostaglandins E; Thrombosis | 1981 |
Endogenous agents in platelet thrombosis.
Topics: Adenosine Diphosphate; Arteriosclerosis; Blood Vessels; Chlorpromazine; Collagen; Epoprostenol; Humans; Platelet Adhesiveness; Platelet Aggregation; Thrombosis | 1981 |
Dosage frequency for suppression of platelet function by low dose aspirin therapy.
Topics: Adenosine Diphosphate; Aspirin; Cell Survival; Collagen; Depression, Chemical; Dose-Response Relationship, Drug; Epinephrine; Humans; Malondialdehyde; Platelet Aggregation; Platelet Function Tests; Thrombosis; Thromboxane B2 | 1982 |
Platelet aggregation and multiple sclerosis.
Topics: Adenosine Diphosphate; Adolescent; Adult; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Platelet Aggregation; Serotonin; Thrombosis | 1982 |
[Induction of pulmonary thrombosis in the rat by i.v. injections of ADP and the antithrombotic activity of triflusal].
Topics: Adenosine Diphosphate; Animals; Female; Fibrinolytic Agents; Injections, Intravenous; Lung Diseases; Male; Rats; Rats, Inbred Strains; Salicylates; Thrombosis | 1982 |
The influence of blood flow on the behaviour of blood cells with particular reference to thrombosis.
Topics: Adenosine Diphosphate; Arteriosclerosis; Blood Cells; Collagen; Erythrocytes; Humans; Platelet Aggregation; Regional Blood Flow; Thrombosis | 1981 |
[Action of tioxaprofen on platelet function (author's transl)].
Topics: Adenosine Diphosphate; Alkaline Phosphatase; Anti-Inflammatory Agents; Blood Platelets; Blood Urea Nitrogen; Creatinine; Humans; In Vitro Techniques; Malondialdehyde; Platelet Aggregation; Propionates; Thrombosis; Thromboxanes | 1982 |
[New techniques in the study of the interaction between blood platelets and the arterial wall (author's transl)].
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Electric Stimulation; Mesenteric Arteries; Mesenteric Vascular Occlusion; Microscopy, Electron; Platelet Aggregation; Rats; Thrombosis | 1981 |
Thrombosis in arteries: mechanisms and prevention.
Topics: Adenosine Diphosphate; Chlorpromazine; Hemodynamics; Humans; Platelet Adhesiveness; Platelet Aggregation; Thrombosis | 1980 |
Abnormalities of platelet aggregation in sickle cell disease.
Topics: Adenosine Diphosphate; Adolescent; Anemia, Sickle Cell; Child; Epinephrine; Humans; Platelet Aggregation; Thrombosis | 1980 |
[Limits of platelet aggregation tests for investigating thromboses (author's transl)].
Topics: Adenosine Diphosphate; Adult; Aged; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Thrombosis | 1980 |
Platelet adhesion and release: interfacial concentration of released materials.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Collagen; Erythrocytes; Platelet Adhesiveness; Platelet Aggregation; Swine; Thrombosis | 1981 |
Antithrombotic effect of a humanized anti-GPIIb/IIIa monoclonal antibody, YM207, in a photochemically induced thrombosis model in monkeys.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Binding Sites, Antibody; Blood Coagulation; Enzyme-Linked Immunosorbent Assay; Fibrinolytic Agents; Humans; In Vitro Techniques; Photochemistry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Saimiri; Thrombosis | 1995 |
Comparison of antiplatelet effects of FK409, a spontaneous nitric oxide releaser, with those of TRK-100, a prostacyclin analogue.
Topics: Adenosine Diphosphate; Administration, Oral; Analysis of Variance; Animals; Blood Platelets; Blood Pressure; Blood Pressure Determination; Dose-Response Relationship, Drug; Epoprostenol; Male; Nitro Compounds; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombosis | 1995 |
Thrombolytic and antithrombotic efficacy of the platelet GPIIb-IIIa antagonist DMP728.
Topics: Adenosine Diphosphate; Animals; Arterial Occlusive Diseases; Clinical Protocols; Dogs; Drug Therapy, Combination; Female; Femoral Artery; Fibrinolysis; Hemodynamics; Humans; Male; Mesylates; Models, Cardiovascular; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding; Recurrence; Streptokinase; Thrombosis | 1994 |
Nonpeptide glycoprotein IIb/IIIa inhibitors. 5. Antithrombotic effects of MK-0383.
Topics: Adenosine Diphosphate; Animals; Coronary Circulation; Dogs; Female; Hemostasis; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Streptokinase; Thrombosis; Tirofiban; Tissue Plasminogen Activator; Tyrosine | 1995 |
In vivo antithrombotic effect of triflavin, an Arg-Gly-Asp containing peptide on platelet plug formation in mesenteric microvessels of mice.
Topics: Acute Disease; Adenosine Diphosphate; Alprostadil; Amino Acid Sequence; Animals; Blood Pressure; Endothelium, Vascular; Fluorescein; Fluoresceins; Heparin; Indomethacin; Male; Mesentery; Mice; Mice, Inbred ICR; Molecular Sequence Data; Oligopeptides; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pulmonary Embolism; Thrombosis; Venules | 1994 |
Enhancement of thrombotic arterial occlusion following cholesterol feeding in the guinea-pig: a role for thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arterial Occlusive Diseases; Cholesterol, Dietary; Collagen; Femoral Artery; Guinea Pigs; Male; Photochemistry; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thrombosis; Thromboxane A2; Time Factors | 1994 |
Inhibitory effect of tetrahydroberberine on platelet aggregation and thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Berberine; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Thrombosis; Thromboxane B2 | 1994 |
An optoelectronic registration method as applied to PAF-mediated hydrogen peroxide induced arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Animals, Laboratory; Arterial Occlusive Diseases; Arterioles; Electroshock; Endothelium, Vascular; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Male; Mesenteric Arteries; Platelet Activating Factor; Rats; Rats, Wistar; Thrombosis | 1994 |
Platelet deposition induced by severely damaged vessel wall is inhibited by a boroarginine synthetic peptide with antithrombin activity.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Blood Coagulation; Blood Platelets; Boron Compounds; Collagen; Endothelium, Vascular; Fibrinolytic Agents; Heparin; Male; Molecular Sequence Data; Oligopeptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Swine; Thrombin; Thrombosis | 1994 |
Effect of aspirin and clopidogrel on platelet-dependent tissue factor expression in endothelial cells.
Topics: Adenosine Diphosphate; Animals; Aorta; Aspirin; Blood Platelets; Cattle; Clopidogrel; Endothelium, Vascular; Female; Ligation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Thionucleotides; Thrombin; Thromboplastin; Thrombosis; Ticlopidine; Vena Cava, Inferior | 1994 |
Platelet, antithrombin, and fibrinolytic activities in taurine-deficient and taurine-replete cats.
Topics: Adenosine Diphosphate; Animals; Antithrombins; Blood Platelets; Cat Diseases; Cats; Collagen; Fibrinolysis; Male; Plasminogen; Platelet Aggregation; Taurine; Thrombosis | 1993 |
Primary polycythaemia: diagnosis by non-conventional positive criteria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Biomarkers; Blood Platelets; Cells, Cultured; Colony-Forming Units Assay; Diagnosis, Differential; Erythrocytes; Erythropoietin; Female; Humans; Interferon Type I; Interleukin-3; Ischemia; Male; Polycythemia; Polycythemia Vera; Recombinant Proteins; Reference Values; Thrombosis | 1993 |
Thrombus formation and platelet-vessel wall interaction in the nephrotic syndrome under flow conditions.
Topics: Adenosine Diphosphate; Adolescent; Adult; Angiotensin III; Arachidonic Acid; Biopsy; Blood Coagulation Factors; Blood Platelets; Collagen; Endothelium, Vascular; Erythrocyte Deformability; Extracellular Matrix; Female; Fibrin; Fibrinogen; Humans; In Vitro Techniques; Kidney; Male; Microscopy, Electron, Scanning; Middle Aged; Muscle, Smooth, Vascular; Nephrotic Syndrome; Platelet Adhesiveness; Platelet Aggregation; Thrombosis; Umbilical Arteries | 1994 |
Platelet activation and thrombosis: studies in a patient with essential thrombocythemia.
Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Aspirin; Blood Platelets; Disease Susceptibility; Female; Fibrinogen; Flow Cytometry; Humans; Mesenteric Arteries; Mesenteric Vascular Occlusion; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Portal Vein; Receptors, Purinergic P2; Splenic Vein; Thrombocythemia, Essential; Thrombosis; Ticlopidine | 1996 |
Interleukin-2 induces increased platelet-endothelium interactions: a potential mechanism of toxicity.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Collagen; Ear; Endothelium, Vascular; Fluorescein-5-isothiocyanate; Interleukin-2; Light; Lymphocyte Function-Associated Antigen-1; Male; Mice; Mice, Inbred C57BL; Microcirculation; Platelet Aggregation; Serum Albumin, Bovine; Thrombosis | 1996 |
Effects of granulocyte colony-stimulating factor on the hemostatic system in healthy volunteers.
Topics: Adenosine Diphosphate; Adult; Antithrombin III; Collagen; Filgrastim; Granulocyte Colony-Stimulating Factor; Hemostasis; Humans; Male; Middle Aged; Peptide Hydrolases; Platelet Aggregation; Recombinant Proteins; Thrombosis; Thromboxane B2 | 1996 |
Platelet function and platelet-leukocyte adhesion in symptomatic coronary heart disease. Effects of intravenous magnesium.
Topics: Adenosine Diphosphate; Adult; Aged; Angina Pectoris; Aspirin; Cell Adhesion; Coronary Disease; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Leukocytes; Magnesium; Male; Middle Aged; Neutrophils; P-Selectin; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Thrombosis | 1996 |
Effects of cocaine on human platelet aggregation in vitro.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cocaine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Middle Aged; Narcotics; Platelet Aggregation; Thrombosis | 1996 |
Antithrombotic effect in vivo of thrombotic substances adsorbed on a platinum surface.
Topics: Adenosine Diphosphate; Adsorption; Albumins; Animals; Arachidonic Acid; Biocompatible Materials; Catheterization; Collagen; Female; Fibrinogen; Male; Platelet Activation; Platinum; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Surface Properties; Thrombin; Thrombosis; Venae Cavae | 1996 |
YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits platelet-rich thrombosis in mice.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation; Blood Platelets; Disease Models, Animal; Enzyme Activation; Fibrinolytic Agents; Fluorescein; Fluoresceins; Guanylate Cyclase; Indazoles; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Embolism; Serum Globulins; Solubility; Thrombosis | 1997 |
Nonpeptide glycoprotein IIb/IIIa inhibitors. 15. Antithrombotic efficacy of L-738,167, a long-acting GPIIb/IIIa antagonist, correlates with inhibition of adenosine diphosphate-induced platelet aggregation but not with bleeding time prolongation.
Topics: Adenosine Diphosphate; Animals; Azepines; Bleeding Time; Disease Models, Animal; Dogs; Drug Administration Routes; Fibrinolytic Agents; Macaca mulatta; Pan troglodytes; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Sulfonamides; Thrombosis | 1997 |
Hyperactivity and increased hydrogen peroxide formation in platelets of NIDDM patients.
Topics: Adenosine Diphosphate; Aged; beta-Thromboglobulin; Blood Platelets; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniques; Male; Middle Aged; Platelet Activating Factor; Risk Factors; Thrombin; Thrombosis | 1997 |
Nitric oxide released from activated platelets inhibits platelet recruitment.
Topics: Adenosine Diphosphate; Adult; Biotin; Blood Platelets; Cyclic GMP; Cytoplasmic Granules; Flow Cytometry; Humans; Microelectrodes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; P-Selectin; Platelet Activation; Platelet Aggregation; Serotonin; Thrombosis | 1997 |
The in vitro and in vivo pharmacological profiles of a platelet glycoprotein IIb/IIIa antagonist, NSL-9403.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Femoral Artery; Fibrinogen; Humans; Male; Mice; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pulmonary Embolism; Thrombosis | 1997 |
A baboon model for hematologic studies of cardiopulmonary bypass.
Topics: Adenosine Diphosphate; Animals; Biomarkers; Blood Physiological Phenomena; Blood Platelets; Blood Pressure; Blood Proteins; Cardiac Output; Cardiopulmonary Bypass; Complement Activation; Female; Heart Rate; Leukocytes; Models, Cardiovascular; Neutrophil Activation; Oxygenators; Papio; Platelet Activation; Thrombosis | 1997 |
Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease.
Topics: Adenosine Diphosphate; Adult; Angina Pectoris; Cell Adhesion; Cell Adhesion Molecules; Cell Count; Cell Degranulation; Cell Movement; Coronary Artery Disease; Coronary Disease; Coronary Vessels; Epinephrine; Female; Flow Cytometry; Humans; Leukocytes; Male; Middle Aged; Monocytes; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation; Receptors, Thrombin; Thrombosis | 1998 |
Increased potency and decreased elimination of lamifiban, a GPIIb-IIIa antagonist, in patients with severe renal dysfunction.
Topics: Acetates; Adenosine Diphosphate; Adult; Aged; Bleeding Time; Creatinine; Female; Half-Life; Hematoma; Humans; Kidney Diseases; Kidney Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Oligopeptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis; Tyrosine | 1998 |
Fibrinogen as a factor of thrombosis: experimental study.
Topics: Adenosine Diphosphate; Animals; Disease Models, Animal; Fibrinogen; Humans; In Vitro Techniques; Male; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Rats; Rats, Wistar; Risk Factors; Thromboembolism; Thrombophlebitis; Thrombosis | 1998 |
Increased platelet responsiveness following coronary stenting. Heparin as a possible aetiological factor in stent thrombosis.
Topics: Adenosine Diphosphate; Aged; Angina Pectoris; Anticoagulants; Female; Flow Cytometry; Heparin; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Platelet Activation; Platelet Count; Stents; Thrombosis; Warfarin | 1998 |
Changes in platelet membrane glycoproteins before bone marrow transplantation and after engraftment--a pilot study.
Topics: Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Bone Marrow Transplantation; Case-Control Studies; Female; Fibrinogen; Flow Cytometry; Fluorescent Dyes; Graft Survival; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Quinacrine; Thrombosis; Transplantation Conditioning | 1998 |
Oxygen-free radicals and nitric oxide are involved in the thrombus growth produced by iontophoresis of ADP.
Topics: Adenosine Diphosphate; Animals; Catalase; Enzyme Inhibitors; In Vitro Techniques; Iontophoresis; Male; Mesenteric Veins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Platelet Aggregation; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thrombosis | 1998 |
Antithrombotic effect of SM-20302, a nonpeptide GPIIb/IIIa antagonist, in a photochemically induced thrombosis model in guinea pigs.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Benzene Derivatives; Guinea Pigs; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis | 1999 |
Nucleotides and cd39: principal modulatory players in hemostasis and thrombosis.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Blood Coagulation; Blood Flow Velocity; Hemostasis; Mice; Mice, Knockout; Platelet Activation; Signal Transduction; Thrombosis | 1999 |
More pieces of the platelet activation puzzle slide into place.
Topics: Adenosine Diphosphate; Animals; GTP-Binding Proteins; Mice; Platelet Activation; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thrombosis | 1999 |
Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Female; Male; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Aggregation; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombination, Genetic; Thrombosis | 1999 |
Stimulation of nitric oxide synthesis and protective role of insulin in acute thrombosis in vivo.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Blood Glucose; Coronary Disease; Enzyme Inhibitors; Epoprostenol; Female; Insulin; Kinetics; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Thrombosis | 1999 |
Antiplatelet and antithrombotic effects of orbofiban, a new orally active GPIIb/IIIa antagonist, in guinea pigs.
Topics: Adenosine Diphosphate; Administration, Oral; Alanine; Animals; Arteriovenous Shunt, Surgical; Aspirin; beta-Alanine; Bleeding Time; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Guinea Pigs; Hemostasis; Hypercholesterolemia; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Thrombosis; Urea | 2000 |
In vivo dynamic real-time monitoring and quantification of platelet-thrombus formation: use of a local isotope detector.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anticoagulants; Aspirin; Blood Platelets; Carotid Arteries; Carotid Artery Injuries; Computer Systems; Fibrinolytic Agents; Gene Expression; Heparin; Indium Radioisotopes; Partial Thromboplastin Time; Plasminogen Activator Inhibitor 1; Radionuclide Imaging; RNA, Messenger; Swine; Thrombosis; Ultrasonography, Doppler; Uridine Diphosphate; Uridine Triphosphate | 2000 |
The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arteriovenous Shunt, Surgical; Binding, Competitive; Bleeding Time; Blood Platelets; Clopidogrel; Collagen; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Male; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thionucleotides; Thiophenes; Thrombin; Thrombosis; Ticlopidine; Time Factors; Tritium | 2000 |
Antiplatelet and antithrombotic effect of D-003.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Collagen; Dose-Response Relationship, Drug; Fatty Acids; Fibrinolytic Agents; Guinea Pigs; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombosis | 2000 |
Comparative study of antithrombotic effect of a low molecular weight heparin and unfractionated heparin in an ex vivo model of deep arterial injury.
Topics: Adenosine Diphosphate; Animals; Arteries; Blood Coagulation Tests; Blood Flow Velocity; Collagen; Disease Models, Animal; Fibrin; Fibrinogen; Fibrinolytic Agents; Hematologic Tests; Heparin; Heparin, Low-Molecular-Weight; Perfusion; Platelet Aggregation; Platelet Function Tests; Swine; Thrombosis | 2000 |
The effects of polysulfonate derivative (GL 2021) on coagulation in vitro and thrombosis in vivo.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Anticoagulants; Arterioles; Blood Coagulation; Collagen; Disease Models, Animal; Fibrinolytic Agents; Humans; Injections, Intravenous; Lasers; Male; Mesenteric Arteries; Partial Thromboplastin Time; Platelet Adhesiveness; Platelet Aggregation; Platelet Count; Polymers; Prothrombin Time; Rats; Rats, Wistar; Sulfonic Acids; Thrombin Time; Thrombosis | 2000 |
Effect of aspirin on platelet desaggregation induced by SR121566, a potent GP-IIb/IIIa antagonist.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Benzylamines; Blood Flow Velocity; Blood Platelets; Carotid Arteries; Disease Models, Animal; Electric Stimulation; Female; Fibrinolytic Agents; Humans; Male; Oligopeptides; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Recombinant Proteins; Thiazoles; Thrombosis; Thrombospondins; Tissue Plasminogen Activator | 2000 |
Effects of acetyl salicylic acid therapy on an experimental thrombosis induced by laser beam.
Topics: Adenosine Diphosphate; Animals; Aspirin; Bleeding Time; Disease Models, Animal; Fibrinogen; Lasers; Male; Partial Thromboplastin Time; Platelet Aggregation; Rats; Rats, Wistar; Thrombosis | 2000 |
A pharmacodynamic study of clopidogrel in chronic hemodialysis patients.
Topics: Adenosine Diphosphate; Arterial Occlusive Diseases; Chronic Disease; Clopidogrel; Dose-Response Relationship, Drug; Hemostasis; Humans; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Renal Dialysis; Renal Insufficiency; Thrombosis; Ticlopidine | 2000 |
Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Bleeding Time; Blood Platelets; C-Reactive Protein; Coagulants; Collagen; Crotalid Venoms; Dose-Response Relationship, Drug; Flow Cytometry; Integrin beta1; Integrins; Lectins, C-Type; Mice; Mice, Knockout; Platelet Adhesiveness; Platelet Aggregation; Platelet Count; Platelet Membrane Glycoproteins; Receptors, Collagen; Signal Transduction; Stress, Mechanical; Thrombin; Thrombosis | 2001 |
Increased circulating platelet-leukocyte aggregates in myeloproliferative disorders is correlated to previous thrombosis, platelet activation and platelet count.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Blood Platelets; Cell Adhesion; Cell Adhesion Molecules; Cell Aggregation; Female; Flow Cytometry; Humans; Leukocyte Count; Leukocytes; Male; Middle Aged; Myeloproliferative Disorders; Platelet Activation; Platelet Aggregation; Platelet Count; Proteins; Receptors, Thrombin; Thrombophilia; Thrombosis | 2001 |
Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity.
Topics: Adenosine Diphosphate; Animals; Arteries; Blood Platelets; Leptin; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Phenotype; Platelet Aggregation; Thrombosis | 2001 |
Role of a novel soluble nucleotide phospho-hydrolase from sheep plasma in inhibition of platelet reactivity: hemostasis, thrombosis, and vascular biology.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Dinucleoside Phosphates; Egtazic Acid; Enzyme Inhibitors; Fibrinolytic Agents; Hemostasis; Hydrolysis; Kinetics; Nitrophenols; Nucleotidases; Platelet Aggregation; Platelet Aggregation Inhibitors; Sheep; Thrombosis; Thymidine Monophosphate | 2002 |
Role of ADP receptor P2Y(12) in platelet adhesion and thrombus formation in flowing blood.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aged; Analysis of Variance; Blood Platelets; Humans; Male; Membrane Proteins; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis | 2002 |
Antithrombotic effect of PMC, a potent alpha-tocopherol analogue on platelet plug formation in vivo.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Aspirin; Bleeding Time; Blood Pressure; Chromans; Fluorescein; Mesenteric Arteries; Mice; Mice, Inbred ICR; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Embolism; Rats; Rats, Sprague-Dawley; Thrombosis | 2002 |
A membrane-bound enzyme in rabbit aorta capable of inhibiting adenosine-diphosphate-induced platelet aggregation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aorta; Apyrase; Cell Extracts; Cell Membrane; Phosphoric Monoester Hydrolases; Platelet Aggregation; Rabbits; Thrombosis | 1977 |
Antithrombotic properties of vascular endothelium.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Blood Vessels; Endothelium; Epoprostenol; Humans; Platelet Aggregation; Prostaglandins; Rabbits; Thrombosis | 1977 |
A potent new inhibitor of platelet aggregation and experimental thrombosis, anagrelide (BL-4162A).
Topics: Adenosine Diphosphate; Animals; Carotid Arteries; Collagen; Dogs; Electricity; Fibrinolytic Agents; Haplorhini; Hemorrhage; Humans; Imidazoles; Lasers; Macaca mulatta; Platelet Aggregation; Quinazolines; Rabbits; Rats; Thrombosis | 1979 |
The effect of 15-hydroperoxyarachidonic acid on the arterial wall during ADP-induced local platelet thrombosis.
Topics: Adenosine Diphosphate; Arachidonic Acids; Arteries; Blood Platelets; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Leukotrienes; Lipid Peroxides; Peroxidases; Thrombosis | 1979 |
[Effect of an enzyme, thrombic type, defibrase, on the formation of the white intra-arterial thrombus].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Batroxobin; Electric Stimulation; Mesenteric Arteries; Peptide Hydrolases; Platelet Aggregation; Rats; Thrombosis | 1975 |
The inhibitory effect of PGI2 (prostacyclin) on white platelet arterial thrombus formation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Dose-Response Relationship, Drug; Epoprostenol; Prostaglandins; Rats; Thrombosis | 1979 |
ADP-induced platelet aggregation in retinal venous occlusions.
Topics: Adenosine Diphosphate; Adult; Female; Humans; Male; Middle Aged; Platelet Aggregation; Retinal Vein; Thrombosis | 1978 |
The effects of treatment with aspirin and an antithrombotic agent SH1117 upon platelet thrombus formation in living blood vessels.
Topics: Adenosine Diphosphate; Animals; Aspirin; Biphenyl Compounds; Drug Synergism; Fibrinolytic Agents; Male; Platelet Aggregation; Rabbits; Sulfones; Thrombosis | 1977 |
The role of stagnation point flow in the formation of platelet thrombi on glass surfaces in tubes with various geometry.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Glass; Lasers; Microscopy, Electron, Scanning; Rheology; Thrombosis | 1978 |
[The initial stage of thrombus formation in early stages of arteriosclerosis].
Topics: Adenosine Diphosphate; Antigen-Antibody Complex; Arteries; Arteriosclerosis; Basement Membrane; Blood Coagulation; Blood Viscosity; Humans; Platelet Aggregation; Prostaglandins; Smoking; Thrombosis | 1978 |
Antiplatelet and antithrombogenic effects of suloctidil.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Pressure; Dogs; Female; Fibrinolytic Agents; Haplorhini; Male; Mice; Mice, Inbred Strains; Platelet Aggregation; Propanolamines; Rats; Thrombophlebitis; Thrombosis | 1976 |
Platelet function, blood coagulation and fibrinolysis in Behcet's syndrome.
Topics: Adenosine Diphosphate; Adult; Behcet Syndrome; Blood Coagulation; Blood Platelets; Factor VIII; Fibrinogen; Fibrinolysis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4; Thrombosis | 1977 |
The synergistic effect of aspirin and dipyridamole upon platelet thrombi in living blood vessels.
Topics: Adenosine Diphosphate; Alloxan; Animals; Aspirin; Dipyridamole; Drug Synergism; Male; Platelet Aggregation; Rabbits; Thrombosis | 1977 |
Growth kinetics of platelet thrombi.
Topics: Adenosine Diphosphate; Blood Flow Velocity; Blood Platelets; Models, Biological; Platelet Adhesiveness; Platelet Aggregation; Thrombosis | 1977 |
ADP-induced platelet aggregation in vitro in patients with ischemic heart disease and peripheral thromboatherosclerosis.
Topics: Adenosine Diphosphate; Adult; Aged; Arteriosclerosis; Coronary Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Thrombosis | 1977 |
Dietary fatty acids and arterial thrombosis: effects and mechanism of action with special reference to linoleic acid.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Coagulation; Blood Platelets; Cholesterol; Collagen; Dietary Fats; Fatty Acids; Fibrinogen; Humans; Linoleic Acids; Platelet Aggregation; Prostaglandin Endoperoxides; Rats; Thrombin; Thrombosis | 1977 |
Editorial: Much hope but little proof.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Coronary Disease; Humans; Physical Exertion; Platelet Aggregation; Thrombosis | 1976 |
Thrombosis induced in vivo in the mesenteric artery of rats. An electron microscopic study of the initial phases.
Topics: Adenosine Diphosphate; Animals; Electric Stimulation; Fibrin; Male; Mesenteric Arteries; Microscopy, Electron; Platelet Aggregation; Rats; Thrombosis | 1976 |
Physico-chemical explanation of blood cell adhesion in thrombus formation.
Topics: Adenosine Diphosphate; Cell Adhesion; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Erythrocytes; Models, Biological; Platelet Adhesiveness; Platelet Aggregation; Thrombosis | 1976 |
Endothelial injury induced by thrombin or thrombi.
Topics: Adenosine Diphosphate; Animals; Aorta; Arteriosclerosis; Elastic Tissue; Endothelium; Fibrin; Fibrinogen; Male; Microscopy, Electron; Microscopy, Phase-Contrast; Platelet Aggregation; Rabbits; Sonication; Thrombin; Thrombosis; Tissue Extracts | 1975 |
Packed cells, platelet-rich plasma, and adenosine diphosphate in the production of occlusive vascular changes in lungs of rabbits.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Erythrocytes; Hyperplasia; Hypertension, Pulmonary; Hypertrophy; Plasma; Pulmonary Artery; Rabbits; Spasm; Thrombosis | 1975 |
[Anticoagulants in therapy of patients with heart valve prostheses].
Topics: Adenosine Diphosphate; Anticoagulants; Blood Coagulation Factors; Coumarins; Heart Valve Prosthesis; Humans; Platelet Adhesiveness; Platelet Aggregation; Postoperative Complications; Serotonin; Thrombosis | 1975 |
The effects on platelet aggregation of oral prostaglandin E2 used for the induction of labour.
Topics: Adenosine Diphosphate; Administration, Oral; Blood Cell Count; Depression, Chemical; Female; Humans; Labor, Induced; Platelet Adhesiveness; Platelet Aggregation; Pregnancy; Prostaglandins E; Thrombosis | 1975 |
[Thrombocythemia in infants. Apropos of a casel].
Topics: Adenosine Diphosphate; Anemia; Epinephrine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Platelet Adhesiveness; Platelet Aggregation; Splenomegaly; Thrombocythemia, Essential; Thrombosis | 1975 |
Proceedings: Early endothelial injury.
Topics: Adenosine Diphosphate; Animals; Arteries; Arteriosclerosis; Blood Platelets; Endothelium; Plasminogen Activators; Rabbits; Thrombin; Thrombosis; Time Factors | 1975 |
Proceedings: In vivo activity of tieclopidine, a new drug with platelet aggregation inhibiting, antisludge and antithrombotic properties.
Topics: Adenosine Diphosphate; Animals; Collagen; Disease Models, Animal; Platelet Aggregation; Rats; Thrombosis | 1975 |
Platelet hypersensitivity and intravascular coagulation in paroxysmal nocturnal hemoglobinuria.
Topics: Adenosine Diphosphate; Blood Platelets; Collagen; Complement System Proteins; Disseminated Intravascular Coagulation; Epinephrine; Female; Hemoglobinuria, Paroxysmal; Humans; Middle Aged; Nucleotides; Platelet Aggregation; Thrombophlebitis; Thrombosis; Time Factors | 1975 |
Effect of ajoene, the major antiplatelet compound from garlic, on platelet thrombus formation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Disulfides; Endothelium, Vascular; Garlic; Indium Radioisotopes; Plant Extracts; Plants, Medicinal; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Binding; Rheology; Stress, Mechanical; Sulfoxides; Swine; Thrombosis; von Willebrand Factor | 1992 |
[Antiplatelet effect of clopidogrel].
Topics: Adenosine Diphosphate; Adolescent; Adult; Animals; Bleeding Time; Clopidogrel; Disease Models, Animal; Dogs; Drug Evaluation; Female; Humans; Intracranial Embolism and Thrombosis; Male; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Rabbits; Rats; Thrombosis; Ticlopidine | 1992 |
Reduction in the ADP release from shear-stressed red blood cells by fish oil administration.
Topics: Adenosine Diphosphate; Adult; Age Factors; Blood Viscosity; Erythrocyte Deformability; Erythrocyte Membrane; Erythrocytes; Fish Oils; Humans; Male; Membrane Lipids; Middle Aged; Thrombosis | 1992 |
Platelet serotonin content and microcirculation haemostasis in spontaneous arterial hypertension in rats.
Topics: Adenosine Diphosphate; Animals; Arterioles; Blood Platelets; Hemostasis; Humans; Hypertension; Lasers; Microcirculation; Rats; Rats, Inbred SHR; Serotonin; Thrombosis; Venules | 1992 |
Inhibition of platelet function in a baboon thrombosis model.
Topics: Adenosine Diphosphate; Animals; Antibodies, Monoclonal; Bleeding Time; Blood Vessel Prosthesis; Dose-Response Relationship, Immunologic; Male; Papio; Platelet Aggregation; Platelet Function Tests; Platelet Membrane Glycoproteins; Predictive Value of Tests; Thrombosis | 1991 |
Rapid and reversible inhibition by low density lipoprotein of the endothelium-dependent relaxation to hemostatic substances in porcine coronary arteries. Heat and acid labile factors in low density lipoprotein mediate the inhibition.
Topics: Acids; Adenosine Diphosphate; Animals; Calcimycin; Coronary Vasospasm; Coronary Vessels; Endothelium, Vascular; Female; Hot Temperature; In Vitro Techniques; Lipoproteins, LDL; Male; Muscle Relaxation; Nitric Oxide; Platelet Activating Factor; Swine; Thrombin; Thrombosis | 1990 |
Computerized optoelectronic induction and registration of arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Computers; Disease Models, Animal; Electric Stimulation; Endothelium, Vascular; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombosis | 1990 |
Neutrophils inhibit platelet reactivity by multiple mechanisms: relevance to thromboregulation.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Communication; Humans; Neutrophils; Platelet Activation; Thrombosis | 1990 |
High susceptibility to ADP-induced thrombus formation in mast cell-deficient W/Wv mice.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Epitopes; Fibrinogen; Humans; Male; Mast Cells; Mesenteric Veins; Mice; Mice, Mutant Strains; Platelet Aggregation; Platelet Count; Thrombosis | 1985 |
Evidence for chronic platelet hyperaggregability and in vivo activation in cyclosporin-treated renal allograft recipients.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adult; Blood Platelets; Cyclosporins; Epoprostenol; Female; Humans; Iloprost; In Vitro Techniques; Kidney Transplantation; Male; Middle Aged; Platelet Aggregation; Thrombosis; Time Factors | 1988 |
Thrombectomy, lysis, or heparin treatment: concurrent therapies of deep vein thrombosis: therapy and experimental studies.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Animals; Child; Combined Modality Therapy; Endothelium, Vascular; Heparin; Humans; Microscopy, Electron, Scanning; Middle Aged; Rabbits; Streptokinase; Thrombophlebitis; Thrombosis; Venae Cavae | 1989 |
Mathematical analysis of mural thrombogenesis. Concentration profiles of platelet-activating agents and effects of viscous shear flow.
Topics: Adenosine Diphosphate; Antithrombin III; Blood Platelets; Collagen; Computer Simulation; Heparin; Humans; Kinetics; Mathematics; Microscopy, Fluorescence; Models, Biological; Platelet Activation; Regional Blood Flow; Thrombin; Thrombosis; Thromboxane A2; Video Recording; Viscosity; von Willebrand Factor | 1989 |
Reduced thrombus formation in vivo after administration of pentoxifylline (Trental).
Topics: Adenosine Diphosphate; Animals; Cheek; Cricetinae; Fibrinolytic Agents; Injections, Intraperitoneal; Male; Mesocricetus; Microcirculation; Pentoxifylline; Theobromine; Thrombosis | 1989 |
A new index for collagen induced platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Arterial Occlusive Diseases; Blood Platelets; Collagen; Disease Susceptibility; Ellagic Acid; Factor XII; Humans; Platelet Aggregation; Platelet Count; Platelet Function Tests; Rabbits; Thrombosis | 1989 |
[Arterial thrombosis--an experimental approach].
Topics: Adenosine Diphosphate; Animals; Arteries; Arterioles; Electric Injuries; Endothelium, Vascular; Microscopy, Electron; Platelet Aggregation; Rats; Rats, Inbred Strains; Thrombosis | 1989 |
Platelet aggregation, haematocrit, and fibrinogen.
Topics: Adenosine Diphosphate; Erythrocytes; Fibrinogen; Hematocrit; Humans; Platelet Aggregation; Thrombosis | 1985 |
[Some recent biochemical and physiologic aspects of the vascular endothelium].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Capillary Permeability; Carbon Dioxide; Endothelium; Energy Metabolism; Enzymes; Humans; Muscle, Smooth, Vascular; Platelet Aggregation; Pulmonary Gas Exchange; Receptors, Cell Surface; Thrombosis; Vascular Resistance | 1985 |
Antithrombotic activity of glomerular adenosine diphosphatase in the glomerular basement membrane of the rat kidney.
Topics: Adenosine Diphosphate; Animals; Apyrase; Basement Membrane; Histocytochemistry; Kidney Glomerulus; Microscopy, Electron; Phosphoric Monoester Hydrolases; Platelet Aggregation; Rats; Thrombosis | 1987 |
Roles of arachidonate metabolites in thrombus formation and leukocyte migration: analyses at microcirculatory level.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Cell Adhesion; Cell Movement; Cheek; Cricetinae; Epoprostenol; Indomethacin; Leukotriene B4; Mesocricetus; Microcirculation; Mouth Mucosa; Neutrophils; Platelet Aggregation; Rats; Rats, Inbred Strains; Thrombosis | 1987 |
Anti-thrombotic effect of KC-404, a novel cerebral vasodilator.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Cerebrovascular Disorders; Electroencephalography; Heart Block; Lauric Acids; Male; Mice; Mice, Inbred ICR; Pyridines; Rats; Rats, Inbred Strains; Thrombosis; Vasodilator Agents | 1986 |
Abnormal aggregation accompanies abnormal platelet Ca2+ handling in arterial thrombosis.
Topics: Adenosine Diphosphate; Aminoquinolines; Blood Platelets; Calcimycin; Calcium; Chlortetracycline; Collagen; Cytoplasmic Granules; Humans; Kinetics; Platelet Aggregation; Thrombosis; Time Factors | 1987 |
ADP plays a key role in thrombogenesis in rats.
Topics: Adenosine Diphosphate; Animals; Clopidogrel; Cyclooxygenase Inhibitors; Disease Models, Animal; Female; In Vitro Techniques; Ketanserin; Platelet Aggregation; Rats; Rats, Inbred Strains; Serotonin; Thrombosis; Ticlopidine | 1988 |
Exchange of cyclooxygenase dependent metabolites between vessel wall and platelets in arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Imidazoles; Male; Mesenteric Arteries; Platelet Aggregation; Propionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane A2; Tranylcypromine | 1988 |
[Vasculo-thrombocyte hemostasis in arterial hypertension].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Aorta; Glycogen; Hemostasis; Lasers; Microcirculation; Platelet Aggregation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Thrombin; Thrombosis | 1988 |
Cardiovascular and antithrombotic effects of ZK 96 480, a novel metabolically stable carbacyclin derivative with oral activity.
Topics: Adenosine Diphosphate; Animals; Blood Pressure; Epoprostenol; Fibrinolysis; Heart Rate; Platelet Aggregation; Rats; Rats, Inbred SHR; Thrombosis | 1987 |
[Antiaggregating effect of indobufen. Preliminary results of a study of 20 patients].
Topics: Adenosine Diphosphate; Collagen; Epinephrine; Female; Humans; Isoindoles; Male; Phenylbutyrates; Platelet Aggregation; Thrombosis | 1986 |
Antithrombogenic endothelial cell defense. Basal characteristics in cultured endothelial cells and modulation by short-term and long-term exposure to isosorbide nitrates.
Topics: Adenosine Diphosphate; Animals; Cattle; Cells, Cultured; Endothelium; Female; Humans; Isosorbide; Kinetics; Male; Nitrates; Platelet Aggregation; Sorbitol; Thrombosis; Time Factors | 1987 |
Endothelial injury and platelet thrombosis in mesenteric arteries of rats: a scanning electron microscopy study.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Endothelium; Male; Mesenteric Arteries; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains; Thrombosis | 1986 |
Platelet activation induced by a human neuroblastoma tumor cell line is reduced by prior administration of ticlopidine.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cell Line; Female; Humans; In Vitro Techniques; Male; Middle Aged; Neuroblastoma; Perfusion; Platelet Aggregation; Thiophenes; Thrombosis; Ticlopidine | 1986 |
Visualization and analysis of mural thrombogenesis on collagen, polyurethane and nylon.
Topics: Adenosine Diphosphate; Biocompatible Materials; Blood Platelets; Collagen; Humans; In Vitro Techniques; Microscopy, Fluorescence; Nylons; Polyurethanes; Signal Processing, Computer-Assisted; Thrombin; Thrombosis; Thromboxane B2 | 1986 |
Platelet active concentration profiles near growing thrombi. A mathematical consideration.
Topics: Adenosine Diphosphate; Blood Platelets; Humans; Mathematics; Models, Biological; Platelet Aggregation; Thrombin; Thrombosis; Thromboxane A2 | 1986 |
In vivo arterial platelet-vessel wall interaction and thrombosis: induction, on-line registration and ultrastructural control.
Topics: Adenosine Diphosphate; Animals; Arteries; Blood Platelets; Glycoproteins; Guinea Pigs; Male; Microscopy, Electron, Scanning; Platelet Activating Factor; Polysaccharides; Quinacrine; Rats; Rats, Inbred Strains; Thrombosis | 1985 |
[Effect of bromhexine on microthrombosis in animal experiments].
Topics: Adenosine Diphosphate; Ambroxol; Animals; Arachidonic Acid; Arachidonic Acids; Bromhexine; Collagen; Disseminated Intravascular Coagulation; Humans; In Vitro Techniques; Lung; Platelet Aggregation; Pulmonary Embolism; Pulmonary Surfactants; Rabbits; Rats; Thrombosis | 1985 |
The tachyphylactic effect of arachidonic acid on in-vivo ADP induced arterial platelet thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Coagulation; Drug Synergism; Rats; Thrombosis | 1985 |
The effect of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (paf-acether) on the arterial wall.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arteries; Diterpenes; Edetic Acid; Epoprostenol; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Quinacrine; Thrombosis | 1985 |
The effect of inhibition of endothelial cell cyclooxygenase on arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Endothelium; Flurbiprofen; Indomethacin; Male; Mesenteric Arteries; Rats; Rats, Inbred Strains; Thrombosis | 1985 |
Platelet survival and function in rats with enhanced thrombotic tendency.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Survival; Collagen; Doxorubicin; Epoprostenol; In Vitro Techniques; Male; Platelet Aggregation; Rats; Thrombosis; Thromboxane B2 | 1985 |
Antihemostatic and antithrombotic effects of capsaicin in comparison with aspirin and indomethacin.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Capsaicin; Hemostasis; Indomethacin; Mice; Mice, Inbred ICR; Platelet Aggregation; Thromboembolism; Thrombosis | 1985 |
Adenosine diphosphate as a mediator of platelet aggregation in vivo: an editorial view.
Topics: Adenosine Diphosphate; Arteriosclerosis; Blood Platelets; Hemostasis; Humans; Platelet Aggregation; Thrombosis | 1985 |
Effect of cilostazol on platelet aggregation and experimental thrombosis.
Topics: Adenosine Diphosphate; Animals; Aspirin; Azoles; Cilostazol; Dogs; Fibrinolytic Agents; Humans; In Vitro Techniques; Mice; Platelet Aggregation; Rabbits; Tetrazoles; Thrombosis; Vasodilator Agents | 1985 |
The ratio MDA/MDAa as a new index of platelet hyperactivity.
Topics: Adenosine Diphosphate; Antithrombin III; Biometry; Blood Platelets; Diabetes Mellitus; Humans; In Vitro Techniques; Malonates; Malondialdehyde; Phospholipases A; Phospholipases A2; Platelet Aggregation; Thrombosis | 1985 |
Thrombus formation by the application of thrombin to the outer surface of mouse mesenteric vein: comparison with the application of ADP.
Topics: Adenosine Diphosphate; Animals; Male; Mesenteric Veins; Mice; Mice, Inbred C57BL; Thrombin; Thrombosis; Videotape Recording | 1985 |
[Thrombogenesis].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Epinephrine; Histamine Release; Humans; Platelet Adhesiveness; Serotonin; Thrombin; Thrombosis | 1970 |
In vivo effects of dicoumarol derivatives on platelet behaviour.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation Tests; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Coumarins; Densitometry; Dicumarol; Electric Conductivity; Erythrocytes; Guinea Pigs; Hemolysis; Injections, Intravenous; Osmotic Fragility; Platelet Adhesiveness; Premedication; Prothrombin Time; Rabbits; Rats; Thrombosis; Time Factors | 1972 |
The effect of anti-inflammatory drugs on the aggregation and adhesiveness of platelets, red cells and leukocytes.
Topics: Adenosine Diphosphate; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Cell Adhesion; Chloroquine; Collagen; Dextrans; Edetic Acid; Endotoxins; Erythrocytes; Fibrinogen; Flufenamic Acid; Gelatin; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Phenylbutazone; Phenylpropionates; Platelet Adhesiveness; Prednisolone; Rats; Thrombosis | 1972 |
Leucocytes and thrombosis. II. Relationship between leucocyte behaviour and divalent cations, sulphydryl groups, red cells and adenosine diphosphate.
Topics: Adenosine Diphosphate; Anticoagulants; Blood Platelets; Calcium; Cell Aggregation; Citrates; Cyanides; Edetic Acid; Erythrocytes; Humans; Leukocytes; Magnesium; Plasma Substitutes; Potassium; Thrombosis | 1973 |
Studies on the antithrombotic effect of dextran effect on platelet 5-hydroxytryptamine and adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Blood Cell Count; Blood Platelets; Centrifugation; Chromium Radioisotopes; Dextrans; Dose-Response Relationship, Drug; Edetic Acid; Fibrinolytic Agents; Humans; Male; Serotonin; Thrombosis | 1973 |
Blood and neoplastic diseases. Haemostasis, haemorrhage, and thrombosis.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Blood Vessels; Dextrans; Disseminated Intravascular Coagulation; Fibrinolysin; Fibrinolysis; Hemorrhage; Hemostasis; Humans; Platelet Adhesiveness; Snakes; Thrombosis; Venoms | 1974 |
Platelet function in hyperlipoproteinemia.
Topics: Adenosine Diphosphate; Adult; Arteriosclerosis; Blood Platelets; Carbon Radioisotopes; Cholesterol; Clot Retraction; Collagen; Epinephrine; Female; Heparin Antagonists; Humans; Hypercholesterolemia; Hyperlipidemias; Lipoproteins; Lipoproteins, LDL; Male; Middle Aged; Nucleotides; Platelet Adhesiveness; Serotonin; Thrombosis; Triglycerides | 1974 |
[Platelets, ADP, cAMP, and antiplatelet drugs].
Topics: Adenosine Diphosphate; Anticoagulants; Blood Platelets; Collagen; Cyclic AMP; Humans; Platelet Adhesiveness; Thrombin; Thrombosis | 1974 |
Clofibrate reversal of platelet hypersensitivity in hyperbetalipoproteinemia.
Topics: Adenosine Diphosphate; Arteriosclerosis; Blood Platelets; Carbon Radioisotopes; Clofibrate; Collagen; Epinephrine; Female; Humans; Hypercholesterolemia; Hyperlipidemias; Lipoproteins, LDL; Male; Nucleotides; Platelet Aggregation; Thrombosis | 1974 |
Proceedings: Effect of feeding with sucrose and other carbohydrates on platelet function in rats.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Dietary Carbohydrates; Glucose; Male; Platelet Adhesiveness; Rats; Starch; Sucrose; Thrombosis | 1974 |
Dihomo-gamma-linolenate suppresses platelet aggregation when administered in vitro or in vivo.
Topics: 8,11,14-Eicosatrienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Fatty Acids, Unsaturated; Humans; Linolenic Acids; Peroxides; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Prostaglandins E; Rats; Thrombosis | 1974 |
The effect of some platelet aggregating and potential thrombosis-promoting substances on the development of experimental arterial thrombosis.
Topics: Adenosine Diphosphate; Aminocaproates; Animals; Aprotinin; Benzopyrans; Carotid Artery Thrombosis; Epinephrine; Female; Ketones; Rats; Serotonin; Tannins; Thrombin; Thrombosis | 1973 |
[Platelet aggregates studied by the Swank method of microfiltration under pressure. Pharmacological and pathological applications].
Topics: Adenosine Diphosphate; Anticoagulants; Blood Coagulation Disorders; Citrates; Female; Filtration; Humans; Infections; Myocardial Infarction; Norepinephrine; Platelet Adhesiveness; Platelet Aggregation; Poisoning; Pre-Eclampsia; Pregnancy; Pulmonary Embolism; Sepsis; Thrombosis; Wounds and Injuries | 1974 |
[Mechanism of action of inhibitors of adhesiveness to collagen].
Topics: Adenosine Diphosphate; Blood Coagulation; Cell Membrane; Collagen; Glucosyltransferases; Platelet Adhesiveness; Surface Properties; Thrombosis | 1972 |
Effect of anaesthesia on platelet function in vitro and in vivo.
Topics: Acid-Base Equilibrium; Adenosine Diphosphate; Anesthesia, Intravenous; Animals; Blood Cell Count; Blood Flow Velocity; Blood Platelets; Carbon Dioxide; Densitometry; Depression, Chemical; Ear; Endothelium; Erythrocyte Count; In Vitro Techniques; Lasers; Microcirculation; Oxygen; Partial Pressure; Pentobarbital; Platelet Adhesiveness; Rabbits; Skin Window Technique; Thrombosis; Time Factors | 1972 |
A qualitative platelet defect in severe vitamin B 12 deficiency. Response, hyperresponse, and thrombosis after vitamin B 12 therapy.
Topics: Adenosine Diphosphate; Aged; Biological Assay; Blood Cell Count; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelet Disorders; Collagen; Colorimetry; Epinephrine; Female; Fibrinogen; Folic Acid; Humans; Lacticaseibacillus casei; Male; Middle Aged; Platelet Adhesiveness; Prothrombin Time; Radioisotope Dilution Technique; Schilling Test; Thromboplastin; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
Effect of detergents on platelet electrophoresis and aggregation, and the possible relation of plasma surface activity to thrombosis.
Topics: Adenosine Diphosphate; Arteries; Blood Platelets; Cell Movement; Cetylpyridinium; Detergents; Electrophoresis; Humans; Ions; Norepinephrine; Plasma; Platelet Adhesiveness; Surface Tension; Thrombosis; Vascular Diseases | 1972 |
Assessment of antithrombotic agents: effects of dipyridamole analogues on platelet behaviour.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Cerebral Arteries; Dipyridamole; Electrophoresis; Ethylamines; Morpholines; Norepinephrine; Piperazines; Platelet Adhesiveness; Pyrimidines; Rabbits; Structure-Activity Relationship; Thiophenes; Thrombosis | 1972 |
[Experimental arterial thrombosis. In vivo and in the vitro effects of aspirin and prostaglandin E1].
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Blood Platelets; Cerebral Arteries; Collagen; In Vitro Techniques; Prostaglandins; Rabbits; Thrombosis | 1972 |
Influence of some drugs on platelet aggregation: a study in hypertensive patients.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents; Aspirin; Benzyl Compounds; Blood Cell Count; Blood Coagulation; Blood Platelets; Dimethylamines; Dipyridamole; Humans; Hypertension; In Vitro Techniques; Indazoles; Indomethacin; Phenylbutazone; Platelet Adhesiveness; Reserpine; Thrombosis; Time Factors | 1972 |
The influence of dietary fats on experimental arterial thrombosis in vivo in rats.
Topics: Adenosine Diphosphate; Animals; Aorta, Abdominal; Blood Coagulation Factors; Blood Platelets; Butter; Cocos; Dietary Carbohydrates; Dietary Fats; Dose-Response Relationship, Drug; Endothelium; Fatty Acids; Fibrinolytic Agents; Linoleic Acids; Lipoproteins; Rats; Thrombosis; Time Factors | 1972 |
Inhibition of thrombosis on vascular catheters in cats.
Topics: Adenosine Diphosphate; Animals; Aspirin; Carbon Isotopes; Catheterization; Cats; Connective Tissue; Humans; In Vitro Techniques; Injections, Intraperitoneal; Injections, Intravenous; Platelet Adhesiveness; Serotonin; Thrombosis; Vena Cava, Inferior | 1973 |
[The pathogenesis of thrombosis].
Topics: Adenosine Diphosphate; Anticoagulants; Blood Coagulation; Blood Platelets; Humans; Platelet Adhesiveness; Thrombin; Thrombosis | 1973 |
Clinical application of platelet aggregation.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Dipyridamole; Epinephrine; Humans; Intracranial Embolism and Thrombosis; Platelet Adhesiveness; Thrombin; Thrombosis; Warfarin | 1973 |
[Experimental platelet aggregation and arterial thrombosis. Effect of aspirin].
Topics: Adenosine Diphosphate; Animals; Arterial Occlusive Diseases; Aspirin; Blood Platelets; Collagen; Epinephrine; Humans; In Vitro Techniques; Platelet Adhesiveness; Rabbits; Thrombosis | 1973 |
Inhibition of platelet thrombus formation by dextran.
Topics: Adenosine Diphosphate; Animals; Dextrans; Drug Synergism; Heparin; In Vitro Techniques; Platelet Adhesiveness; Postoperative Complications; Rabbits; Thrombosis | 1973 |
An acute effect of cigarette smoking on platelet function. A possible link between smoking and arterial thrombosis.
Topics: Adenosine Diphosphate; Blood Cell Count; Blood Coagulation Factors; Blood Platelets; Fatty Acids, Nonesterified; Female; Humans; Lipoproteins; Male; Platelet Adhesiveness; Smoking; Stress, Psychological; Thrombosis; Time Factors | 1973 |
Abnormalities of platelet function in patients with polycythemia vera.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Blood Cell Count; Blood Coagulation Tests; Blood Platelet Disorders; Child; Collagen; Epinephrine; Female; Hematocrit; Hemorrhage; Humans; Male; Middle Aged; Platelet Adhesiveness; Polycythemia Vera; Thrombin; Thrombosis | 1973 |
Inhibition of platelet aggregation and of experimental thrombosis by sudoxicam.
Topics: Adenosine Diphosphate; Administration, Oral; Amides; Animals; Anti-Inflammatory Agents; Blood Platelets; Dogs; Guinea Pigs; In Vitro Techniques; Injections, Intravenous; Models, Biological; Platelet Adhesiveness; Rabbits; Tendons; Thiazines; Thiazoles; Thrombosis; Time Factors; Tissue Extracts | 1973 |
[Thrombocytes, thrombin, thrombosis and heart infarct].
Topics: Adenosine Diphosphate; Blood Platelets; Humans; Myocardial Infarction; Platelet Adhesiveness; Thrombin; Thrombosis | 1973 |
Human platelet reactivity during stressful diagnostic procedures.
Topics: Adenosine Diphosphate; Adult; Angiography; Arteriosclerosis; Blood Cell Count; Cardiac Catheterization; Catecholamines; Fatty Acids, Nonesterified; Female; Glass; Humans; Male; Middle Aged; Platelet Adhesiveness; Stress, Psychological; Thrombosis; Time Factors; Urography | 1973 |
[Hyperaggregability of platelet in acute stage of thrombosis (author's transl)].
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Child; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Thrombosis | 1973 |
Inhibition of platelet-induced thrombus formation.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Brain Diseases; Dipyridamole; Epinephrine; Glomerulonephritis; Heart Valve Prosthesis; Humans; Hypertension, Malignant; Ischemia; Myocardial Infarction; Platelet Adhesiveness; Postoperative Complications; Prostaglandins; Pyrimidines; Thromboembolism; Thrombophlebitis; Thrombosis; Xanthines | 1974 |
Atherosclerosis and thrombosis.
Topics: Adenosine Diphosphate; Animals; Arteriosclerosis; Blood Platelets; Humans; Platelet Adhesiveness; Regional Blood Flow; Thrombosis | 1974 |
Prostaglandins, essential fatty acids, platelet function and thrombosis.
Topics: Adenosine Diphosphate; Animals; Collagen; Fatty Acids, Nonesterified; Platelet Adhesiveness; Prostaglandins; Rats; Serotonin; Thrombin; Thrombosis | 1974 |
Thrombosis, a review.
Topics: Adenosine Diphosphate; Arteriosclerosis; Blood Coagulation; Blood Platelets; Coronary Disease; Hemostasis; Platelet Adhesiveness; Thrombosis | 1972 |
Classification of thrombocytosis based on platelet function tests: correlation with hemorrhagic and thrombotic complications.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Cell Count; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelets; Collagen; Epinephrine; Female; Hemorrhage; Humans; Lipoproteins; Male; Middle Aged; Myeloproliferative Disorders; Platelet Adhesiveness; Prothrombin Time; Splenectomy; Thrombocytosis; Thrombosis | 1972 |
Effect of a new anti-inflammatory drug, fenoprofen, on platelet aggregation and thrombus formation.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Collagen; Depression, Chemical; Drug Antagonism; Ethers; Extracorporeal Circulation; Humans; In Vitro Techniques; Mesentery; Microcirculation; Phenylbutazone; Platelet Adhesiveness; Propionates; Rabbits; Thrombosis | 1972 |
Localization of ferritin-conjugated anti-fibrin-fibrinogen in platelet aggregates produced in vitro.
Topics: Adenosine Diphosphate; Antigen-Antibody Complex; Blood Platelets; Ferritins; Fibrinogen; Humans; Immunoelectrophoresis; In Vitro Techniques; Microscopy, Electron; Platelet Adhesiveness; Thrombosis | 1972 |
Electron microscopic observations of platelets in rats fed on different fat diets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Aggregation; Cell Membrane; Cottonseed Oil; Dietary Fats; Erythrocytes; Fats, Unsaturated; Leukocytes; Linseed Oil; Lung; Male; Microscopy, Electron; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Inbred Strains; Thrombosis | 1972 |
[Pharmacodynamic prevention of thrombosis].
Topics: Adenosine Diphosphate; Amitriptyline; Anticoagulants; Aspirin; Collagen; Dipyridamole; Guanethidine; Humans; Imipramine; Papaverine; Thrombin; Thrombosis | 1971 |
[Pathogenesis of thrombosis. Pathologic-anatomic views].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Coagulation Factors; Blood Flow Velocity; Blood Platelets; Calcium; Platelet Adhesiveness; Serotonin; Thrombin; Thrombophlebitis; Thrombosis | 1971 |
Platelet aggregation by rat liver. Evidence for ADP as major factor.
Topics: Absorption; Adenine Nucleotides; Adenosine Diphosphate; Animals; Charcoal; Dialysis; Hydrogen-Ion Concentration; Light; Liver; Platelet Adhesiveness; Rats; Temperature; Thrombosis | 1971 |
[Effect of drugs on blood platelet characteristics].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Blood Platelets; Epinephrine; Fatty Acids, Nonesterified; Humans; Phenylbutazone; Platelet Adhesiveness; Rabbits; Thrombin; Thromboembolism; Thrombosis | 1971 |
Involvement of platelets and microthrombi in experimental decompression sickness: similarities with disseminated intravascular coagulation.
Topics: Adenosine; Adenosine Diphosphate; Air; Animals; Blood Cell Count; Blood Platelets; Cerebral Cortex; Decompression Sickness; Disseminated Intravascular Coagulation; Erythrocyte Aggregation; Injections, Intra-Arterial; Injections, Intravenous; Lung; Male; Platelet Adhesiveness; Rabbits; Rats; Serotonin; Thrombosis | 1971 |
Anti-thrombotic activity of a benzo(c)(1,6)naphthyridine.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Epinephrine; Humans; Naphthyridines; Pentobarbital; Platelet Adhesiveness; Rabbits; Rats; Thrombosis | 1971 |
Antithrombotic and fibrinolytic effect of bencyclane.
Topics: Adenosine Diphosphate; Animals; Appendix; Benzyl Compounds; Cheek; Cricetinae; Cycloheptanes; Drug Synergism; Fibrinolysis; Fumarates; Humans; Microcirculation; Platelet Adhesiveness; Propylamines; Quaternary Ammonium Compounds; Rabbits; Rats; Streptokinase; Thrombosis; Vasodilator Agents | 1971 |
Platelets, coagulation and in vitro thrombus formation.
Topics: Adenosine Diphosphate; Animals; Benzopyrans; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Collagen; Dogs; In Vitro Techniques; Male; Platelet Adhesiveness; Silicones; Stimulation, Chemical; Thrombosis | 1971 |