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adenosine diphosphate and Obesity

adenosine diphosphate has been researched along with Obesity in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.00)18.7374
1990's8 (20.00)18.2507
2000's17 (42.50)29.6817
2010's11 (27.50)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Friebel, J; Hassanein, A; Jakobs, K; Landmesser, U; Puccini, M; Rauch, C; Rauch, U1
Cao, X; Han, X; Huang, WY; Jia, W; Li, J; Peng, S; Peng, Y; Wang, L; Xu, Y; Ye, J; Ye, X; Zhang, S; Zhang, X; Zhou, Y1
Carroll, CC; Hoffman, N; Katsanos, CS; Kras, KA; Patel, SH; Roust, LR1
Bordner, AJ; Cordova, JM; Langlais, PR; Lefort, N; Mandarino, LJ; McLean, CG; Mielke, C; Ozkan, SB; Te, JA; Willis, WT1
Antoun, G; Dent, R; Harper, ME; McMurray, F; McPherson, R; Patten, DA; Peixoto, AC; Slack, RS; Thrush, AB1
Herma Renkema, G; Ritschel, T; Russel, FG; Schirris, TJ; Smeitink, JA; Willems, PH1
Chouchani, ET; Cohen, P; Erickson, BK; Gygi, SP; Hasenfuss, SC; Jedrychowski, MP; Kajimura, S; Kazak, L; Laznik-Bogoslavski, D; Lu, GZ; Shinoda, K; Spiegelman, BM; Vetrivelan, R1
Ha, E; Ha, TK; Hwang, GS; Jung, J; le Roux, CW; Lee, D; Lee, J; Lho, Y; Nam, M; Ryu, DH1
Brunmeir, R; Garcia-Miralles, M; Ge, X; Han, W; Julien, SG; Kim, SY; Kn, BP; Li, H; Ma, W; McFarlane, C; Pouladi, MA; Röder, PV; Sim, CK; Sinnakannu, JR; Velan, SS; Wu, J; Xie, W; Xu, F; Yaligar, J; Zhang, Q1
Chan, WP; Heresztyn, T; Horowitz, JD; Liberts, EA; Marber, MS; Norman, RJ; Rajendran, S; Saha, M; Willoughby, SR1
Dubouchaud, H; Favier, R; Goglia, F; Guigas, B; Leverve, XM; Moreno, M; Taleux, N; Weitzel, JM1
Anderson, EJ; Boyle, KE; Cortright, RN; Houmard, JA; Kane, DA; Kang, L; Lin, CT; Lustig, ME; Neufer, PD; Price, JW; Rabinovitch, PS; Szeto, HH; Wasserman, DH; Woodlief, TL1
Böhmer, AE; Knorr, L; Lesczinski, DN; Lhullier, F; Moreira, JD; Müller, AP; Oses, JP; Perry, ML; Souza, CG; Souza, DG; Souza, DO; Viola, GG1
Bergmann, S; Knöfler, R; Kuhlisch, E; Lee-Kirsch, MA; Lohse, J; Naeke, A; Schweigel, J; Siegert, G; Suttorp, M1
Cao, W; Hong, T; Liu, HY; Liu, Z; Mei, S; Ning, J; Yang, X1
Gremmel, T; Kopp, CW; Koppensteiner, R; Panzer, S; Seidinger, D; Steiner, S1
Buemi, M; Corica, F; Corsonello, A; De Domenico, D; Ientile, R; Loddo, S; Malara, A; Perticone, F1
Lassila, R; Tamminen, M; Vehkavaara, S; Westerbacka, J; Yki-Järvinen, H1
Anfossi, G; Massucco, P; Mattiello, L; Russo, I; Trovati, M1
Mayhan, WG; Schwaninger, RM; Sun, H1
Chan, CB; Joseph, JW; Koshkin, V; Lowell, BB; Saleh, MC; Sivitz, WI; Wheeler, MB; Zhang, CY1
Czekay, RP; Dellas, C; Giandomenico, G; Koschnick, S; Loskutoff, DJ1
Bakker, SJ; Ciapaite, J; Diamant, M; Heine, RJ; Krab, K; van Eikenhorst, G; Westerhoff, HV1
Ikeda, T; Ishizawa, M; Ishizuka, T; Kajita, K; Matsubara, K; Matsumoto, M; Morita, H; Sugiyama, C; Uno, Y1
Bielicki, G; Boirie, Y; Chanseaume, E; Freyssenet, D; Morio, B; Renou, JP; Tardy, AL1
Christea, C; Herberg, LL; Landgraf, R; Landgraf-Leurs, MM; Loy, A; Siess, W; Weber, PC1
Anfossi, G; Burzacca, S; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, EM; Piretto, V; Ponziani, MC; Trovati, M1
Bohlen, HG; Lash, JM1
Barbe, F; Burlet, C; Duc, M; Kaminsky, P; Klein, M; Straczek, J; Walker, PM1
Polonsky, KS; Pugh, W; Tang, J; Zhang, H1
Anfossi, G; Burzacca, S; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, EM; Ponziani, MC; Trovati, M1
Bode, C; Kohler, B; Kübler, W; Moser, M; Nordt, TK; Peter, K; Ruef, J1
Maruyama, I; Nakata, M; Yamaji, K1
Bakker, SJ; Gans, RO; Heine, RJ; Teerlink, T; ter Maaten, JC; Westerhoff, HV1
Avcu, F; Durmus, O; Ozata, M; Ozdemir, IC; Yalcin, A; Yilmaz, I1
Konstantinides, S; Koschnick, S; Loskutoff, DJ; Schäfer, K1
Lassila, R; Rissanen, A; Syrjälä, M; Turpeinen, A; Vehkavaara, S; Westerbacka, J; Yki-Järvinen, H1
Howland, JL; Katyare, SS1
Bégin-Heick, N; Fournier, L; Schwartz, JL; Whitfield, JF1
Bégin-Heick, N; McFarlane-Anderson, N1

Trials

1 trial(s) available for adenosine diphosphate and Obesity

ArticleYear
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.
    The Journal of clinical investigation, 2009, Volume: 119, Issue:3

    Topics: Adenosine Diphosphate; Adolescent; Adult; Animals; Antioxidants; Blood Glucose; Body Mass Index; Catalase; Dietary Fats; Electron Transport; Glucose Clamp Technique; Glucose Tolerance Test; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Muscle Fibers, Skeletal; Obesity; Oligopeptides; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Rodentia; Young Adult

2009

Other Studies

39 other study(ies) available for adenosine diphosphate and Obesity

ArticleYear
Being Overweight or Obese Is Associated with an Increased Platelet Reactivity Despite Dual Antiplatelet Therapy with Aspirin and Clopidogrel.
    Cardiovascular drugs and therapy, 2023, Volume: 37, Issue:4

    Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Humans; Obesity; Overweight; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine

2023
ADP Induces Blood Glucose Through Direct and Indirect Mechanisms in Promotion of Hepatic Gluconeogenesis by Elevation of NADH.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adenosine Diphosphate; Animals; Diet; Glucagon; Gluconeogenesis; Glucose; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Obesity; Signal Transduction; Thinness

2021
Plasma Amino Acids Stimulate Uncoupled Respiration of Muscle Subsarcolemmal Mitochondria in Lean but Not Obese Humans.
    The Journal of clinical endocrinology and metabolism, 2017, 12-01, Volume: 102, Issue:12

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Amino Acids; Blood Glucose; Body Mass Index; Female; Hormones; Humans; Male; Mitochondria, Muscle; Muscle, Skeletal; Myofibrils; Obesity; Oxygen Consumption; Sarcolemma; Young Adult

2017
Adenine nucleotide translocase is acetylated in vivo in human muscle: Modeling predicts a decreased ADP affinity and altered control of oxidative phosphorylation.
    Biochemistry, 2014, Jun-17, Volume: 53, Issue:23

    Topics: Acetylation; Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adult; Binding Sites; Body Mass Index; Down-Regulation; Female; Humans; Insulin Resistance; Lysine; Male; Middle Aged; Mitochondria, Muscle; Molecular Docking Simulation; Molecular Dynamics Simulation; Motor Activity; Muscle Proteins; Muscle, Skeletal; Obesity; Oxidative Phosphorylation; Protein Processing, Post-Translational

2014
Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals.
    Diabetologia, 2015, Volume: 58, Issue:12

    Topics: Adenosine Diphosphate; Adult; Diabetes Mellitus, Type 2; Electron Transport Chain Complex Proteins; Electron Transport Complex I; Electron Transport Complex IV; Fatty Acids; Female; Glycated Hemoglobin; Humans; Mitochondria; Muscle, Skeletal; Obesity; Oxidative Phosphorylation; Rectus Abdominis

2015
Mitochondrial ADP/ATP exchange inhibition: a novel off-target mechanism underlying ibipinabant-induced myotoxicity.
    Scientific reports, 2015, Sep-29, Volume: 5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amidines; Animals; Anti-Obesity Agents; Cannabinoid Receptor Antagonists; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Design; Electron Transport Chain Complex Proteins; Humans; Mice; Mitochondria; Mitochondrial ADP, ATP Translocases; Muscle, Skeletal; Myoblasts; Obesity; Oxygen Consumption; Pyrazoles; Reactive Oxygen Species; Receptor, Cannabinoid, CB1; Structure-Activity Relationship

2015
A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.
    Cell, 2015, Oct-22, Volume: 163, Issue:3

    Topics: Adenosine Diphosphate; Adipose Tissue; Adipose Tissue, Brown; Animals; Creatine; Energy Metabolism; Homeostasis; Humans; Ion Channels; Mice; Mitochondria; Mitochondrial Proteins; Obesity; Thermogenesis; Uncoupling Protein 1

2015
Changes in one-carbon metabolism after duodenal-jejunal bypass surgery.
    American journal of physiology. Endocrinology and metabolism, 2016, Apr-15, Volume: 310, Issue:8

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aldehyde Dehydrogenase; AMP-Activated Protein Kinases; Anastomosis, Surgical; Animals; Bariatric Surgery; Betaine-Homocysteine S-Methyltransferase; Blood Glucose; Cystathionine; Cystathionine beta-Synthase; Cysteine; Duodenum; Fatty Acids; Gastric Bypass; Glucose; Glutathione; Glutathione Transferase; Guanine Deaminase; Hypoxanthine; Inosine Monophosphate; Jejunum; Liver; Male; Metabolomics; Obesity; Oxidation-Reduction; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serine; Vitamin B 12

2016
Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle.
    PLoS biology, 2017, Volume: 15, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amaryllidaceae Alkaloids; AMP-Activated Protein Kinases; Animals; Biomarkers; Cell Respiration; Cells, Cultured; Cyclic AMP; Diet; Diet, High-Fat; Energy Metabolism; Enzyme Activation; Fatty Acids; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Muscle Fibers, Skeletal; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Obesity; Oxidation-Reduction; Phenanthridines; Physical Conditioning, Animal; Protective Agents; Reactive Oxygen Species; Signal Transduction

2017
Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects.
    Atherosclerosis, 2009, Volume: 204, Issue:2

    Topics: Adenosine Diphosphate; Adult; Albuterol; Arginine; Body Composition; C-Reactive Protein; Cohort Studies; Endothelial Cells; Endothelium, Vascular; Female; Humans; Inflammation Mediators; Malondialdehyde; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Obesity; Oxidative Stress; Platelet Aggregation; Platelet Function Tests; Polycystic Ovary Syndrome; Stem Cells; Time Factors; Vasodilator Agents

2009
High expression of thyroid hormone receptors and mitochondrial glycerol-3-phosphate dehydrogenase in the liver is linked to enhanced fatty acid oxidation in Lou/C, a rat strain resistant to obesity.
    The Journal of biological chemistry, 2009, Feb-13, Volume: 284, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fatty Acids; Gluconeogenesis; Glycerol; Glycerolphosphate Dehydrogenase; Glycerophosphates; Hepatocytes; Male; Mitochondria, Liver; Monocarboxylic Acid Transporters; NAD; Obesity; Oxidation-Reduction; Rats; Rats, Wistar; Receptors, Thyroid Hormone; Species Specificity

2009
Effects of a highly palatable diet on lipid and glucose parameters, nitric oxide, and ectonucleotidases activity.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2010, Volume: 35, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animal Feed; Animals; Blood Glucose; Dietary Fats; Dietary Sucrose; Enzyme Activation; Glucose Intolerance; Glycerol; Insulin; Lipids; Male; Nitric Oxide; Obesity; Rats; Rats, Wistar

2010
Platelet function in obese children and adolescents.
    Hamostaseologie, 2010, Volume: 30 Suppl 1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; Blood Chemical Analysis; Blood Platelets; Child; Child, Preschool; Female; Humans; Hypercholesterolemia; Male; Obesity; Overweight; Platelet Aggregation; Reference Values; Young Adult

2010
Insulin and insulin signaling play a critical role in fat induction of insulin resistance in mouse.
    American journal of physiology. Endocrinology and metabolism, 2011, Volume: 301, Issue:2

    Topics: Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromones; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fatty Acids; Hepatocytes; Insulin; Insulin Resistance; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mitochondria; Morpholines; Obesity; Receptor, Insulin; RNA, Small Interfering; Signal Transduction

2011
Obesity is associated with poor response to clopidogrel and an increased susceptibility to protease activated receptor-1 mediated platelet activation.
    Translational research : the journal of laboratory and clinical medicine, 2013, Volume: 161, Issue:5

    Topics: Adenosine Diphosphate; Aged; Angioplasty; Blood Platelets; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Female; Humans; Male; Microfilament Proteins; Middle Aged; Obesity; P-Selectin; Phosphoproteins; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptor, PAR-1; Stents; Thrombosis; Ticlopidine; Translational Research, Biomedical

2013
Leptin-dependent platelet aggregation in healthy, overweight and obese subjects.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2003, Volume: 27, Issue:5

    Topics: Adenosine Diphosphate; Adult; Blood Platelets; Body Mass Index; Calcium; Cross-Sectional Studies; Humans; Leptin; Male; Obesity; Platelet Aggregation; Receptors, Cell Surface; Receptors, Leptin; Type C Phospholipases

2003
Obesity is associated with impaired platelet-inhibitory effect of acetylsalicylic acid in nondiabetic subjects.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2003, Volume: 27, Issue:8

    Topics: Adenosine Diphosphate; Analysis of Variance; Arachidonic Acid; Arteriosclerosis; Aspirin; Blood Glucose; Body Mass Index; Body Weight; Dose-Response Relationship, Drug; Female; Humans; Insulin Resistance; Male; Middle Aged; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors

2003
Platelet resistance to the antiaggregating effect of N-acetyl-L-cysteine in obese, insulin-resistant subjects.
    Thrombosis research, 2003, Apr-15, Volume: 110, Issue:1

    Topics: Acetylcysteine; Adenosine Diphosphate; Adult; Amifostine; Antioxidants; Collagen; Cyclic GMP; Drug Resistance; Female; Free Radical Scavengers; Humans; Insulin Resistance; Male; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Superoxide Dismutase

2003
Impaired nitric oxide synthase-dependent dilatation of cerebral arterioles in type II diabetic rats.
    Life sciences, 2003, Nov-14, Volume: 73, Issue:26

    Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arterioles; Blotting, Western; Cerebrovascular Circulation; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Obesity; Rats; Rats, Zucker; Vasodilation; Vasodilator Agents

2003
Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.
    The Journal of biological chemistry, 2004, Dec-03, Volume: 279, Issue:49

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenoviridae; Animals; Blotting, Western; Calcium; Cytosol; Dose-Response Relationship, Drug; Fatty Acids; Fatty Acids, Nonesterified; Glucose; Insulin; Ion Channels; Islets of Langerhans; Lipid Metabolism; Male; Membrane Potentials; Membrane Transport Proteins; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria; Mitochondrial Proteins; Obesity; Oxygen; Palmitic Acid; Phenotype; Polymorphism, Genetic; Reactive Oxygen Species; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Transgenes; Triglycerides; Uncoupling Protein 2

2004
The leptin receptor system of human platelets.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:5

    Topics: Adenosine Diphosphate; Blood Platelets; Blotting, Western; Body Mass Index; Cell Line, Tumor; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Kinetics; Leptin; Ligands; Male; Microscopy, Electron, Transmission; Obesity; Platelet Activation; Platelet Aggregation; Protein Binding; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Thrombosis; Time Factors

2005
Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects. Implications for a mechanism linking obesity and type 2 diabetes.
    The FEBS journal, 2006, Volume: 273, Issue:23

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Diabetes Mellitus, Type 2; Hydrogen Peroxide; Male; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Models, Biological; Obesity; Oxidation-Reduction; Palmitoyl Coenzyme A; Rats; Reactive Oxygen Species

2006
Platelet aggregation in obese and diabetic subjects: association with leptin level.
    Platelets, 2007, Volume: 18, Issue:2

    Topics: Adenosine Diphosphate; Adult; Aged; Blood Platelets; Diabetes Mellitus, Type 2; Female; Humans; Leptin; Male; Middle Aged; Obesity; Platelet Aggregation; Thrombin

2007
Impaired resting muscle energetics studied by (31)P-NMR in diet-induced obese rats.
    Obesity (Silver Spring, Md.), 2008, Volume: 16, Issue:3

    Topics: Adaptation, Physiological; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dietary Fats; Dietary Sucrose; Disease Models, Animal; Energy Metabolism; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Male; Mitochondria, Muscle; Muscle, Skeletal; Obesity; Phosphocreatine; Phosphorus Isotopes; Rats; Rats, Wistar

2008
Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats.
    Prostaglandins, 1981, Volume: 22, Issue:4

    Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epoprostenol; Obesity; Platelet Aggregation; Prostaglandins; Rats; Rats, Zucker; Thromboxane B2; Thromboxanes

1981
Impaired insulin-induced platelet antiaggregating effect in obesity and in obese NIDDM patients.
    Diabetes, 1995, Volume: 44, Issue:11

    Topics: Adenosine Diphosphate; Adult; Blood Platelets; Blood Pressure; Case-Control Studies; Cholesterol; Cholesterol, HDL; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glycated Hemoglobin; Humans; In Vitro Techniques; Insulin; Male; Obesity; Platelet Aggregation Inhibitors; Recombinant Proteins; Reference Values; Triglycerides

1995
Endothelial-dependent vasodilation is preserved in non-insulin-dependent Zucker fatty diabetic rats.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Arterioles; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Intestines; Least-Squares Analysis; Male; Nitric Oxide; Nitroprusside; Obesity; omega-N-Methylarginine; Rats; Rats, Zucker; Thinness; Vasodilation

1995
Muscle bioenergetics in obese Zucker rats.
    The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Electric Stimulation; Energy Metabolism; Female; Magnetic Resonance Spectroscopy; Muscle Contraction; Muscles; Obesity; Phosphates; Phosphocreatine; Rats; Rats, Zucker

1994
Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Blood Glucose; Body Weight; Calcium; Diabetes Mellitus; Diabetes Mellitus, Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Obesity; Perfusion; Potassium Chloride; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Rats, Zucker; Reference Values; Thionucleotides; Time Factors

1996
Platelet resistance to nitrates in obesity and obese NIDDM, and normal platelet sensitivity to both insulin and nitrates in lean NIDDM.
    Diabetes care, 1998, Volume: 21, Issue:1

    Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Blood Glucose; Blood Platelets; Blood Pressure; Body Mass Index; Cholesterol; Cholesterol, HDL; Cyclic GMP; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Male; Nitroglycerin; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Thinness; Triglycerides

1998
Augmented platelet aggregation as predictor of reocclusion after thrombolysis in acute myocardial infarction.
    Thrombosis and haemostasis, 1998, Volume: 80, Issue:6

    Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Anticoagulants; Antithrombin III; Aspirin; Coronary Vessels; Diabetes Mellitus; Drug Therapy, Combination; Female; Fibrinolysis; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Obesity; Peptide Fragments; Peptide Hydrolases; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Platelet Aggregation; Predictive Value of Tests; Prothrombin; Recombinant Proteins; Recurrence; Risk Factors; Smoking; Thrombolytic Therapy; Tissue Plasminogen Activator; Vascular Patency

1998
Effect of leptin in platelet and endothelial cells. Obesity and arterial thrombosis.
    Annals of the New York Academy of Sciences, 2000, Volume: 902

    Topics: Adenosine Diphosphate; Arteriosclerosis; Blood Platelets; Blood Proteins; Carrier Proteins; Endothelium, Vascular; Humans; Leptin; Obesity; Phosphorylation; Platelet Aggregation; Receptors, Cell Surface; Receptors, Leptin; Thrombomodulin

2000
The potential role of adenosine in the pathophysiology of the insulin resistance syndrome.
    Atherosclerosis, 2001, Volume: 155, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Coronary Disease; Diabetes Mellitus, Type 2; Erythropoiesis; Fatty Acids; Heart Rate; Hematocrit; Humans; Hyperinsulinism; Hypertrophy; Insulin Resistance; Islets of Langerhans; Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Biological; Natriuresis; Obesity; Oxidative Phosphorylation; Renal Circulation; Risk Factors; Sodium; Superoxides; Sympathetic Nervous System; Uric Acid; Vasodilation

2001
Leptin does not play a major role in platelet aggregation in obesity and leptin deficiency.
    Obesity research, 2001, Volume: 9, Issue:10

    Topics: Adenosine Diphosphate; Adolescent; Adult; Blood Platelets; Collagen; Epinephrine; Heterozygote; Homozygote; Humans; Leptin; Male; Mutation; Obesity; Osmolar Concentration; Platelet Aggregation

2001
Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity.
    The Journal of clinical investigation, 2001, Volume: 108, Issue:10

    Topics: Adenosine Diphosphate; Animals; Arteries; Blood Platelets; Leptin; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Phenotype; Platelet Aggregation; Thrombosis

2001
Inhibition of platelet-collagen interaction: an in vivo action of insulin abolished by insulin resistance in obesity.
    Arteriosclerosis, thrombosis, and vascular biology, 2002, Volume: 22, Issue:1

    Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Blood Platelets; Body Mass Index; Collagen; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Epinephrine; Glucose; Glucose Clamp Technique; Hemostasis; Humans; Insulin; Insulin Resistance; Obesity; Peptide Fragments; Platelet Aggregation

2002
Enhanced oxidative metabolism in liver mitochondria from genetically obese mice.
    Archives of biochemistry and biophysics, 1978, Volume: 188, Issue:1

    Topics: Adenosine Diphosphate; Animals; Cytochromes; Glutamate Dehydrogenase; Hydroxybutyrate Dehydrogenase; Mice; Mice, Obese; Mitochondria, Liver; Obesity; Organ Size; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Succinate Dehydrogenase

1978
Comparison of the properties of the ATP-sensitive K+ channels of pancreatic beta-cells of lean and obese (ob/ob) C57BL/6J mice.
    The Journal of membrane biology, 1992, Volume: 129, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Fluorescent Antibody Technique; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Obesity; Potassium Channels

1992
mRNA and protein levels of the stimulatory guanine nucleotide regulatory protein Gs are lower in the testis of obese (ob/ob) mice.
    Cellular signalling, 1991, Volume: 3, Issue:3

    Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Blotting, Northern; Cholera Toxin; GTP-Binding Proteins; Immunoblotting; Male; Mice; Mice, Obese; Obesity; RNA, Messenger; Testis

1991