Page last updated: 2024-08-17

adenosine diphosphate and Hyperinsulinism

adenosine diphosphate has been researched along with Hyperinsulinism in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (27.78)18.2507
2000's12 (66.67)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brioudes, E; Grimaldi, M; Karaca, M; Latini, L; Maechler, P; Schalch, T1
Akrouh, A; Halcomb, SE; Nichols, CG; Sala-Rabanal, M1
Grynberg, A; Ovide-Bordeaux, S1
Bescond-Jacquet, A; Grynberg, A; Ovide-Bordeaux, S1
Collins, HW; Daikhin, Y; Hsu, BY; Kelly, A; Kwagh, J; Lazarow, A; Li, C; MacMullen, C; Matschinsky, FM; Matter, A; Najafi, H; Nissim, I; Petty, TJ; Stanley, CA; Yudkoff, M1
Boden, G; Rao, AK; Vaidyula, VR1
Aguilar-Bryan, L; Bryan, J; Clement, JP; Glaser, B; Gonzalez, G; Nestorowicz, A; Nichols, CG; Permutt, MA; Shyng, SL1
Ferrigni, T; Glaser, B; Nestorowicz, A; Nichols, CG; Permutt, MA; Shepard, JB; Shyng, SL1
Peterson, PE; Smith, TJ1
Hiramatsu, H; Momoi, T; Muroi, J; Uematsu, A; Yorifuji, T1
Aynsley-Green, A; Barnes, PD; Chapman, JC; Cosgrove, KE; Docherty, HM; Docherty, K; Dunne, MJ; Hart, AW; Hashmi, MN; James, RF; Kamimura, N; Lindley, KJ; MacFarlane, WM; O'Brien, RE; Shepherd, RM1
Fang, J; Glaser, B; Hsu, BY; Kutyna, K; Ming, JE; Poncz, M; Stanley, CA1
Amachi, T; Ashcroft, FM; Kioka, N; Matsuo, M; Oka, Y; Tanizawa, Y; Trapp, S; Ueda, K1
Ashcroft, F; Ashfield, R; Huopio, H; Kere, J; Komulainen, J; Laakso, M; Lenko, HL; Otonkoski, T; Rahier, J; Reimann, F; Vauhkonen, I1
Bakker, SJ; Gans, RO; Heine, RJ; Teerlink, T; ter Maaten, JC; Westerhoff, HV1
Ammälä, C; Aynsley-Green, A; Barnes, PD; Chapman, JC; Cosgrove, KE; Dunne, MJ; Glaser, B; Kuchinski, N; Lindley, KJ; O'Brien, RE; Schaeppi, M; Sharp, GW; Shepherd, RM; Straub, SG1
Anno, T; Furukawa, S; Inoue, H; Koga, M; Matsuo, K; Nakai, K; Ohta, Y; Oka, Y; Sasaki, T; Tanizawa, Y1
Fang, J; Schmidt, T; Siuzdak, G; Smith, TJ; Stanley, CA; Wu, J1

Reviews

1 review(s) available for adenosine diphosphate and Hyperinsulinism

ArticleYear
Molecular biology of K(ATP) channels and implications for health and disease.
    IUBMB life, 2009, Volume: 61, Issue:10

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Diabetes Mellitus; Disease; Health; Humans; Hyperinsulinism; KATP Channels; Molecular Biology; Mutation; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors

2009

Trials

1 trial(s) available for adenosine diphosphate and Hyperinsulinism

ArticleYear
Platelet and monocyte activation by hyperglycemia and hyperinsulinemia in healthy subjects.
    Platelets, 2006, Volume: 17, Issue:8

    Topics: Adenosine Diphosphate; Adult; Atherosclerosis; Blood Platelets; Blood Proteins; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; Hyperinsulinism; Inflammation; Macrophage Activation; Male; Monocytes; Peptide Fragments; Platelet Aggregation

2006

Other Studies

16 other study(ies) available for adenosine diphosphate and Hyperinsulinism

ArticleYear
Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.
    Human molecular genetics, 2017, 09-15, Volume: 26, Issue:18

    Topics: Adenosine Diphosphate; Amino Acids; Animals; Blood Glucose; Congenital Hyperinsulinism; Glucose; Glutamate Dehydrogenase; Glutamine; HEK293 Cells; Humans; Hyperammonemia; Hyperinsulinism; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mutation; Polymorphism, Single Nucleotide

2017
Docosahexaenoic acid affects insulin deficiency- and insulin resistance-induced alterations in cardiac mitochondria.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 286, Issue:3

    Topics: Adenosine Diphosphate; Animals; Body Weight; Cell Membrane; Creatine Kinase; Diabetes Mellitus, Experimental; Diet; Dietary Fats; Docosahexaenoic Acids; Fatty Acids; Hyperinsulinism; Insulin; Insulin Resistance; Kinetics; Male; Mitochondria, Heart; Oxygen Consumption; Rats; Rats, Wistar

2004
Cardiac mitochondrial alterations induced by insulin deficiency and hyperinsulinaemia in rats: targeting membrane homeostasis with trimetazidine.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:12

    Topics: Adenosine Diphosphate; Animals; Creatine Kinase; Diabetes Mellitus, Experimental; Diet; Fatty Acids; Fructose; Homeostasis; Hyperinsulinism; Insulin; Kinetics; Lipid Metabolism; Male; Membranes; Mitochondria, Heart; Oxygen Consumption; Phospholipids; Rats; Rats, Wistar; Trimetazidine; Vasodilator Agents

2005
Effects of a GTP-insensitive mutation of glutamate dehydrogenase on insulin secretion in transgenic mice.
    The Journal of biological chemistry, 2006, Jun-02, Volume: 281, Issue:22

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium Signaling; Glucose; Glutamate Dehydrogenase; Glutamine; Guanosine Triphosphate; Humans; Hyperinsulinism; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Leucine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Mutation; Recombinant Proteins

2006
Adenosine diphosphate as an intracellular regulator of insulin secretion.
    Science (New York, N.Y.), 1996, Jun-21, Volume: 272, Issue:5269

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Cell Line, Transformed; Chlorocebus aethiops; Cricetinae; Diazoxide; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Molecular Sequence Data; Patch-Clamp Techniques; Point Mutation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Rubidium; Sulfonylurea Receptors; Transfection

1996
Functional analyses of novel mutations in the sulfonylurea receptor 1 associated with persistent hyperinsulinemic hypoglycemia of infancy.
    Diabetes, 1998, Volume: 47, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alleles; Animals; ATP-Binding Cassette Transporters; COS Cells; Cricetinae; Diazoxide; Humans; Hyperinsulinism; Hypoglycemia; Infant; Infant, Newborn; Insulin; Insulin Secretion; Mice; Mutagenesis, Site-Directed; Pancreas; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Rubidium Radioisotopes; Sulfonylurea Receptors; Transfection

1998
The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery.
    Structure (London, England : 1993), 1999, Jul-15, Volume: 7, Issue:7

    Topics: Adenosine Diphosphate; Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Ammonia; Animals; Bacteria; Binding Sites; Cattle; Enzyme Activation; Glutamate Dehydrogenase; Guanosine Triphosphate; Hyperinsulinism; Molecular Sequence Data; NAD; Protein Conformation; Sequence Homology, Amino Acid

1999
Hyperinsulinism-hyperammonemia syndrome caused by mutant glutamate dehydrogenase accompanied by novel enzyme kinetics.
    Human genetics, 1999, Volume: 104, Issue:6

    Topics: Adenosine Diphosphate; Ammonia; Base Sequence; Dose-Response Relationship, Drug; Genetic Markers; Genotype; Glutamate Dehydrogenase; Guanosine Triphosphate; Humans; Hyperinsulinism; Kinetics; Male; Metabolism, Inborn Errors; Molecular Sequence Data; Point Mutation; Polymorphism, Genetic; Syndrome

1999
Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy.
    The Journal of biological chemistry, 1999, Nov-26, Volume: 274, Issue:48

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Calcium; Cell Line; Dose-Response Relationship, Drug; Electrophysiology; Genetic Engineering; Glucose; Homeodomain Proteins; Humans; Hyperinsulinism; Hypoglycemia; Infant; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Mice; Potassium Channels; Potassium Channels, Inwardly Rectifying; Potassium Chloride; Receptors, Drug; Recombinant Fusion Proteins; Sulfonylurea Receptors; Tolbutamide; Trans-Activators; Transfection; Tumor Cells, Cultured

1999
Molecular basis and characterization of the hyperinsulinism/hyperammonemia syndrome: predominance of mutations in exons 11 and 12 of the glutamate dehydrogenase gene. HI/HA Contributing Investigators.
    Diabetes, 2000, Volume: 49, Issue:4

    Topics: Adenosine Diphosphate; Allosteric Site; Amino Acid Sequence; Ammonia; Enzyme Activation; Exons; Female; Glutamate Dehydrogenase; Guanosine Triphosphate; Humans; Hyperinsulinism; Infant; Infant, Newborn; Lymphocytes; Male; Models, Molecular; Molecular Sequence Data; Mutation; Syndrome

2000
Functional analysis of a mutant sulfonylurea receptor, SUR1-R1420C, that is responsible for persistent hyperinsulinemic hypoglycemia of infancy.
    The Journal of biological chemistry, 2000, Dec-29, Volume: 275, Issue:52

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Catalytic Domain; COS Cells; Humans; Hyperinsulinism; Hypoglycemia; Infant; Photoaffinity Labels; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Folding; Receptors, Drug; Sulfonylurea Receptors

2000
Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1.
    The Journal of clinical investigation, 2000, Volume: 106, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; ATP-Binding Cassette Transporters; Binding Sites; Blood Glucose; Child; Child, Preschool; Diazoxide; Female; Finland; Genes, Dominant; Humans; Hyperinsulinism; Male; Mutation, Missense; Pancreas; Pedigree; Polymorphism, Single-Stranded Conformational; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors; Tolbutamide

2000
The potential role of adenosine in the pathophysiology of the insulin resistance syndrome.
    Atherosclerosis, 2001, Volume: 155, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Coronary Disease; Diabetes Mellitus, Type 2; Erythropoiesis; Fatty Acids; Heart Rate; Hematocrit; Humans; Hyperinsulinism; Hypertrophy; Insulin Resistance; Islets of Langerhans; Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Biological; Natriuresis; Obesity; Oxidative Phosphorylation; Renal Circulation; Risk Factors; Sodium; Superoxides; Sympathetic Nervous System; Uric Acid; Vasodilation

2001
Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.
    Diabetes, 2001, Volume: 50, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Calcium; Calcium Signaling; Cytosol; Exocytosis; Genotype; Humans; Hyperinsulinism; In Vitro Techniques; Infant, Newborn; Insulin; Insulin Secretion; Islets of Langerhans; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors

2001
Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydr
    Diabetes, 2002, Volume: 51, Issue:3

    Topics: Adenosine Diphosphate; Animals; Blood Glucose; COS Cells; DNA Mutational Analysis; Female; Glucose; Glutamate Dehydrogenase; Glutamine; Guanosine Triphosphate; Humans; Hyperinsulinism; Hypoglycemia; Infant; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Mutation; Pancreatic Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Transfection; Tumor Cells, Cultured

2002
The structure of apo human glutamate dehydrogenase details subunit communication and allostery.
    Journal of molecular biology, 2002, May-03, Volume: 318, Issue:3

    Topics: Adenosine Diphosphate; Allosteric Regulation; Allosteric Site; Animals; Apoenzymes; Cattle; Crystallography, X-Ray; Glutamate Dehydrogenase; Guanosine Triphosphate; Humans; Hyperammonemia; Hyperinsulinism; Models, Molecular; Mutation; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Static Electricity

2002