adenosine diphosphate has been researched along with Disease Models, Animal in 260 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 42 (16.15) | 18.7374 |
1990's | 37 (14.23) | 18.2507 |
2000's | 72 (27.69) | 29.6817 |
2010's | 98 (37.69) | 24.3611 |
2020's | 11 (4.23) | 2.80 |
Authors | Studies |
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Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Furukawa, Y; Kobayashi, M; Kumagawa, T; Maeda, T; Moro, N; Shijo, K; Yoshino, A | 1 |
Gao, F; Ji, M; Qu, Y; Tan, B; Wang, J; Wang, X; Xie, P; Yang, S; Zhu, A; Zhu, G | 1 |
Baucom, MR; England, L; Goodman, MD; Pritts, TA; Schuster, R; Turner, K; Wallen, TE; Youngs, J | 1 |
Bian, Z; Chang, Y; Chen, W; Huan, Q; Jiang, D; Peng, J; Shen, X; Xiao, H; Xing, T; Zhang, Q | 1 |
Chen, C; Li, J; Liu, H; Song, J; Sun, S; Tu, Y; Wang, C; Wang, Y; Wei, W; Xu, Z; Zhu, S | 1 |
Amorim, JA; Castela, AC; Machado, IF; Palmeira, CM; Rolo, AP; Sinclair, DA; Steegborn, C; Teodoro, JS | 1 |
Bai, X; Liu, P; Zhou, L; Zhu, L | 1 |
Da Silva, RS; Lutte, AH; Majolo, JH | 1 |
Barsunova, K; Birkedal, R; Branovets, J; Karro, N; Laasmaa, M; Lygate, CA; Vendelin, M | 1 |
Alasadi, A; Augeri, D; Cao, B; Collantes, J; Guo, J; Jin, S; Su, X; Tan, V; Tao, H | 1 |
Bradley, JL; Chen, Q; Ge, W; He, F; Hu, J; Ji, X; Lesnefsky, EJ; Ornato, JP; Peberdy, MA; Shabnam, R; Tang, W; Xu, J; Zheng, G | 1 |
Cui, Z; Lv, Y; Ma, X; Sun, B; Yuan, L; Zhang, J; Zhang, L; Zhang, W; Zhao, H; Zhou, D | 1 |
Asante, S; Breeden, J; Buehler, T; Cantilena, A; Chen, L; Dawn, B; Girgis, M; Mahmoudi, SM; Samanta, A; Vincent, RJ; Xuan, YT; Zhao, L | 1 |
Deppen, J; García, AJ; Levit, RD; Shin, EY; Strobel, F; Tirouvanziam, R; Wang, L; Xu, K; Zemskova, M | 1 |
Chauhan, G; Dash, D; Gautam, D; Krishnamurthy, S; Paliwal, P; Patne, SCU | 1 |
Li, L; Li, Y; Lu, N; Meng, F; Wei, Q; Xu, Y; Yuan, J; Zhang, S; Zheng, X | 1 |
Blank, N; Breithausen, B; Delekate, A; Fuhrmann, M; Halle, A; Hansen, JN; Henneberger, C; Keller, A; Keppler, K; Peter, J; Petzold, GC; Plescher, M; Poll, S; Reichenbach, N; Schulte, T | 1 |
Diachkova, N; Iatsyna, O; Kharkhota, M; Kostev, F | 1 |
Chataway, TK; Grantham, HJM; Majd, S; Power, JHT | 1 |
Babinska, A; Chen, XY; Deng, K; Han, JJ; He, KG; Jiang, H; Jiang, XC; Min, XD; Qin, SC; Song, GH; Wang, Y; Xue, J; Yang, CX; Yu, Y; Zhang, X; Zhao, XM | 1 |
Alves, M; Conte, G; D'Orsi, B; De Diego Garcia, L; Engel, T; Henshall, DC; Jimenez-Mateos, EM; Prehn, JHM; Sanz-Rodriguez, A | 1 |
Hagisawa, K; Kinoshita, M; Saitoh, D; Sakai, H; Seki, S; Takeoka, S; Takikawa, M | 1 |
Guo, HF; Hu, MY; Jin, S; Li, J; Liu, C; Liu, L; Liu, XD; Wang, XT; Yu, YL; Zhang, M | 1 |
Ding, Y; Du, H; Fredrickson, V; Fu, P; Geng, X; Guthikonda, M; Hüttemann, M; Ji, X; Ling, F; Meng, R; Peng, C; Sy, C; Tan, X | 1 |
Anderson, EJ; Blanton, HD; DeAntonio, JH; Ding, JM; Johnson, TL; Kent, SD; Lust, RM; Moukdar, F; Thayne, K; Virag, JA | 1 |
Aksentijevic, D; Birkedal, R; Branovets, J; Jepihhina, N; Kotlyarova, S; Lygate, CA; Neubauer, S; Sepp, M; Sokolova, N; Vendelin, M | 1 |
Kim, DS; Kim, HK; Lee, JJ; Myung, CS; Sung, YY; Yang, WK | 1 |
Fujii, T; Fukuda, N; Hashimoto, K; Hongo, K; Inoue, T; Kagemoto, T; Kobirumaki-Shimozawa, F; Kusakari, Y; Morimoto, S; Ohtsuki, I; Terui, T | 1 |
Castro, JF; Figueroa, VA; Hernández, DE; Jiang, JX; Klein, AD; Orellana, JA; Sáez, JC; Sáez, PJ; Vega-Riveros, N; Zanlungo, S | 1 |
Compton, P; Eastwood, JA; Gylys, K; Meyer, DM; Zivin, JA | 1 |
Ahn, YS; Bidot, C; Horstman, LL; Johansen, ME; Jy, W | 1 |
Gupta, N; Li, W; McIntyre, TM; Silverstein, RL; Willard, B | 1 |
Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Kwon, SG; Lee, JH; Moon, JY; Oh, SB; Roh, DH; Yoon, SY | 1 |
Amorini, AM; Belli, A; Di Pietro, V; Lazzarino, G; Logan, A; Signoretti, S; Tavazzi, B; Vagnozzi, R | 1 |
Giachini, FR; Inscho, EW; Leite, R; Lima, VV; Osmond, DA; Tostes, RC; Webb, RC | 1 |
Bao, Y; Chen, Y; Inoue, Y; Junger, WG; Li, X; Sumi, Y; Tanaka, H; Woehrle, T; Yao, Y | 1 |
Gross, PL; Kim, PY; Ni, R; Vaezzadeh, N; Weitz, JI | 1 |
Cui, J; He, W; Lu, K; Ma, D; Ruan, H; Yi, B; Zhao, H | 1 |
Bertone, V; Boncompagni, E; Bottiroli, G; Croce, AC; Ferrigno, A; Freitas, I; Milanesi, G; Piccolini, VM; Tarantola, E; Vairetti, M | 1 |
Boldron, C; Bonnet-Lignon, S; Bono, F; Delesque-Touchard, N; Herbert, JM; Lassalle, G; Millet, L; Pflieger, AM; Salel, V; Savi, P | 1 |
Chu, H; Huang, H; Yu, H; Zhang, SM; Zhu, KJ | 1 |
Kobayashi, K; Noguchi, K; Sakagami, M; Tatsumi, E; Yagi, H; Yamanaka, H | 1 |
Chang, YW; Cheng, JC; Cooper, JA; Huang, CL; Huang, DY; Lin, CC; Tsai, HJ; Tseng, CP | 1 |
Hall, ED; Miller, DM; Singh, IN; Wang, JA | 1 |
Amison, RT; Gresele, P; Keir, S; Manni, G; Momi, S; Morris, A; Page, CP; Pitchford, SC | 1 |
Abrams, CS; Brass, LF; Harper, DC; Kowalska, MA; Marks, MS; Meng, R; Poncz, M; Stalker, TJ; Wang, Y; Wu, J | 1 |
Alarcón, M; Carrasco, G; Fuentes, E; Fuentes, M; Palomo, I | 1 |
Divoky, V; Dolezal, D; Horvathova, M; Kapralova, K; Koralkova, P; Mojzikova, R; Zidova, Z | 1 |
Flaumenhaft, R; Furie, B; Furie, BC; Gopal, S; Jasuja, R; Kim, SH; Sharda, A | 1 |
Chen, M; Chen, Y; Kong, Y; Ming, X; Su, W; Su, X; Wang, Y; Ye, X | 1 |
Chong, CM; Chu, IK; Cui, G; Guo, L; Hoi, MP; Lee, SM; Li, G; Quan, Q; Shan, L; Sun, Y; Wang, Y; Yu, P; Zhang, Z; Zhao, Y | 1 |
Brustovetsky, N; Brustovetsky, T; Hamilton, J; Harris, RA; Pellman, JJ | 1 |
Jin, R; Li, G; Nanda, A; Wang, C; Yan, J | 1 |
Baek, AE; Goonewardena, SN; Hyman, MC; Jo, H; Kanthi, Y; Liao, H; Neral, MK; Pinsky, DJ; Sutton, NR; Visovatti, SH | 1 |
Li, JY; Liu, GR; Liu, XW; Ma, N; Mohamed, I; Yang, YJ; Zhang, JY | 1 |
Handa, M; Hashimoto, M; Ikeda, Y; Kinoshita, M; Maruyama, T; Nishikawa, K; Ogaki, S; Otagiri, M; Taguchi, K; Takeoka, S; Watanabe, H | 1 |
Cheng, X; Hu, H; Hu, M; Ji, J; Liu, Y; Luo, D; Niu, Y; Ouyang, H; Xu, C; Yue, M; Zhou, Q | 1 |
Fan, JY; Han, JY; Li, Q; Liu, YY; Lu, Y; Sun, K; Wang, CS | 1 |
Jakubowski, JA; Mizuno, M; Ohno, K; Sugidachi, A; Tomizawa, A | 1 |
Bandeira-Melo, C; Baptista-Dos-Reis, R; Benjamim, CF; Figueiredo, RT; Mata-Santos, HA; Melo, PA; Muniz, VS; Neves, JS; Pyrrho, AS; Silva-Paiva, J; Strauch, MA; Vicentino, AR; Weller, PF | 1 |
Ampofo, E; Eichler, H; Laschke, MW; Menger, MD; Müller, I; Später, T | 1 |
Frelinger, AL; Gremmel, T; Michelson, AD; Przyklenk, K; Undyala, VV; Wider, J; Wright, GE; Yanachkov, IB; Yanachkova, MI | 1 |
Coutinho-Silva, R; Ferreira, ZS; Meyer-Fernandes, JR; Oliveira, NF; Oliveira, SD; Ornelas, FG; Savio, LE; Silva, CL | 1 |
Hagisawa, K; Handa, M; Iwaya, K; Kinoshita, M; Miyawaki, H; Miyazaki, H; Nishida, Y; Saitoh, D; Sato, S; Seki, S; Shono, S; Suzuki, H; Takeoka, S | 1 |
Fernández-Moreira, D; García-Ruiz, I; Grau, M; Muñoz-Yagüe, T; Solís-Herruzo, JA; Solís-Muñoz, P | 1 |
Agu, RU; Kolathuru, SS; Yeung, PK | 1 |
Abushik, P; Fayuk, D; Giniatullin, R; Giniatullina, R; Guerrero-Toro, C; Ishchenko, Y; Kilinc, E; Koroleva, K; Yegutkin, GG | 1 |
Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG | 1 |
Du, J; Jia, LX; Li, TT; Liu, JL; Liu, O; Liu, Y; Piao, CM; Qi, YF; Zhang, WM | 1 |
Huo, Z; Li, C; Wang, R; Wang, Z; Zhao, Z | 1 |
Chen, A; Chen, M; Chen, X; Dai, W; Dong, Q; Li, W; Li, X; Ou, C; Shen, Y | 1 |
Corscadden, K; Kaur, H; Othman, M; Ware, J | 1 |
Atucha, NM; García-Estañ, J; Iyú, D; Navarro, EG; Ortiz, MC; Romecín, P; Rosado, JA | 1 |
Barbosa, RM; Laranjinha, J; Ledo, A; Lourenço, CF | 1 |
Bottari, NB; Da Silva, AS; de Sá, MF; do Carmo, GM; Doleski, PH; Grando, TH; Gressler, LT; Henker, LC; Leal, DB; Mendes, RE; Monteiro, SG | 1 |
Chen, M; Cui, Q; Dai, K; He, S; Hu, R; Jiang, M; Li, Z; Ruan, C; Tian, J; Yan, R; Zhang, J; Zhang, Y; Zhao, L | 1 |
Audinat, E; Avignone, E; Levavasseur, F; Rassendren, F; Ulmann, L | 1 |
Caldwell, CC; Lentsch, AB | 1 |
Dörner, A; Ebermann, L; Schultheiss, HP; Sterner-Kock, A; Walther, T; Wang, Y; Wika, S | 1 |
Farhan, S; Glogar, D; Gyöngyösi, M; Hemetsberger, H; Hemetsberger, R; Huber, K; Pavo, I; Petrasi, Z; Posa, A; Sperker, W; Strehblow, C | 1 |
Dai, J; Houard, X; Louedec, L; Michel, JB; Philippe, M | 1 |
Barajas-Espinosa, AR; Chisholm, SP; deVries, M; Lomax, AE; Neshat, S; Skeith, L | 1 |
Franke, H; Hengstler, JG; Illes, P; Krügel, U; Rudolph, C; Sauer, C | 1 |
Crain, EJ; Hua, J; Rehfuss, R; Schumacher, WA; Watson, CA; Wong, PC | 1 |
Belair, MF; Berdeaux, A; Bize, A; Bruneval, P; Chenoune, M; Cohen, MV; Couvreur, N; Douheret, M; Downey, JM; Dubois-Rande, JL; Ghaleh, B; Lidouren, F; Mandet, C; Morin, D; Parker, JC; Tissier, R; Zini, R | 1 |
Berger, I; Bertha, B; Folts, J; Sill, JC; Southorn, V | 1 |
Blair, P; Dilks, JR; Flaumenhaft, R; Graham, GJ; Ren, Q; Whiteheart, SW | 1 |
Logue, ES; Menegazzi, JJ; Salcido, DD; Sherman, LD; Suffoletto, BP | 1 |
Bjelobaba, I; Lavrnja, I; Mostarica-Stojkovic, M; Nedeljkovic, N; Pekovic, S; Stojiljkovic, M; Stosic-Grujicic, S | 1 |
Chen, YS; Du, JR; He, Y; Wang, CY; Wang, J; Yu, DK; Zhang, L | 1 |
Cassiman, D; de Vos, R; Freson, K; Hoylaerts, M; Nevens, F; van Geet, C; van Pelt, J; Witters, P | 1 |
Allister, EM; Gyulkhandanyan, AV; Koshkin, V; Lu, H; Wheeler, MB | 1 |
Anantharamaiah, GM; Buga, GM; Chanslor, S; Fogelman, AM; Hough, G; Imaizumi, S; Navab, M; Reddy, ST; Yekta, B | 1 |
Carroll, SH; Chen, H; Eliades, A; Freedman, JE; Koupenova, M; Ravid, K; Toselli, P; Yang, D | 1 |
Antunes, E; Baldissera, L; de Mello, GC; Monteiro, PF; Morganti, RP | 1 |
Battastini, AM; Bonan, CD; da Silveira, VG; de Paula Cognato, G; Figueiró, F; Müller, AP; Perry, ML | 1 |
Brainard, BM; Budsberg, SC; Kleine, SA; Papich, MG | 1 |
Arbel, N; Cleveland, DW; Da Cruz, S; Ilieva, H; Israelson, A; Shoshan-Barmatz, V; Yamanaka, K | 1 |
Fu, LW; Longhurst, JC | 1 |
Boengler, K; Heusch, G; Hilfiker-Kleiner, D; Schulz, R | 1 |
Binker, MG; Binker-Cosen, AA; Cosen-Binker, LI; de Cosen, RH; Gaisano, HY; Richards, D | 1 |
Englezopoulos, CV; Katsouras, CS; Michalis, LK; Moussis, V; Papamichael, ND; Rousouli, KI; Roussa, VD; Stathopoulou, EM; Tellis, CC; Trypou, P; Tselepis, AD; Tsikaris, V | 1 |
Massry, SG | 1 |
Chen, ZY; Inoue, Y; Iwai, T; Terasaki, H; Umeda, M; Yu, KM | 1 |
Bordel, V; Bruckner, B; Ghodsizad, A; Gregoric, I; Kallenbach, K; Karck, M; Kögler, G; Niehaus, M; Ruhparwar, A; Ungerer, MN | 1 |
Coleman Anderson, L; Croce, K; Handy, DE; Jin, RC; Leopold, JA; Loscalzo, J; Mahoney, CE; Ottaviano, F; Tang, SS; Zhang, YY | 1 |
Gopcevic, K; Kojic, Z; Marinkovic, D; Tasic, G | 1 |
Drummond, HA; George, EM; Gilbert, EL; Glover, PH; Granger, JP; LaMarca, B; Masterson, CW; McLemore, GR; Ryan, MJ | 1 |
Braun, A; Dietrich, A; Gupta, S; Mannhalter, C; May, F; Nieswandt, B; Pleines, I; Ramanathan, G; Thielmann, I; Varga-Szabo, D | 1 |
Chen, J; Wang, L; Yang, J; Zhang, Y | 1 |
Bhavaraju, K; Bynagari-Settipalli, YS; Jin, J; Kim, S; Kunapuli, SP; Lakhani, P; Rico, MC; Woulfe, D | 1 |
Song, Q; Wang, S; Zhao, W | 1 |
Groves, JT; Karck, M; Loganathan, S; Merkely, B; Radovits, T; Szabó, C; Szabó, G | 1 |
Bertoncheli, Cde M; Jaques, JA; Leal, CA; Leal, DB; Luz, SC; Pinheiro, Kde V; Rocha, BC; Ruchel, JB; Schetinger, MR; Souza, Vdo C; Stainki, DR; Zimmermann, CE | 1 |
Bouderba, S; Detaille, D; El-Mir, MY; Koceïr, EA; Sánchez-Martín, C; Sanz, MN; Villanueva, GR | 1 |
Cha, KC; Choi, HJ; Hwang, SO; Kim, H; Lee, KH; Nguyen, T; Park, KS | 1 |
Ishida, K; Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K | 1 |
Deelchand, DK; Dubinsky, JM; Gong, W; Henry, PG; Li, T; Tkac, I; Wedel, M; Zacharoff, L | 1 |
Adcock, IM; Arra, C; Cicala, C; Forte, G; Luciano, A; Maiolino, P; Montinaro, A; Morello, S; Pinto, A; Sorrentino, R | 1 |
Bogo, MR; Bonan, CD; Casali, EA; Ferreira, AG; Savio, LE; Scherer, EB; Schmitz, F; Tasca, RA; Vuaden, FC; Wyse, AT | 1 |
Wang, Y; Yang, C; Zhang, Y; Zong, H | 1 |
Doi, M; Hagisawa, K; Handa, M; Iwaya, K; Katsuno, S; Kinoshita, M; Nishikawa, K; Saitoh, D; Sakamoto, T; Seki, S; Shono, S; Suzuki, H; Takeoka, S; Yanagawa, R | 1 |
Miyahara, Y; Okatani, Y; Reiter, RJ; Wakatsuki, A | 1 |
Chen, Y; Davis-Gorman, G; McDonagh, PF; Watson, RR | 1 |
Dinsdale, D; Hoet, PH; Hoylaerts, MF; Nemery, B; Nemmar, A; Smith, T; Vermylen, J; Xu, H | 1 |
Arnout, J; Boon, D; Hoylaerts, MF; Jankowski, M; Vermylen, J; Vreys, I; Wittevrongel, C | 1 |
Chudina, NA; Fesenko, OD; Murina, MA; Roshchupkin, DI; Sergienko, VI | 1 |
Arcucci, O; Bilancio, A; Chiariello, M; Coppola, C; Curcio, A; Falco, M; Indolfi, C; Leccia, A; Leosco, D; Rodriguez, F; Torella, D | 1 |
Discigil, B; Evora, PR; Oeltjen, MR; Pearson, PJ; Schaff, HV | 1 |
Bollaert, PE; Franck, P; Levy, B; Mallie, JP; Mansart, A | 1 |
Day, SM; Duquaine, D; Fay, WP; Khan, BV; Menon, RG; Mundada, LV; Rajagopalan, S | 1 |
Dhar, A; Longorio, MA; Maxfield, DM; Morrison, DC; Van Way, CW | 1 |
Yousif, MH | 1 |
Cazenave, JP; Freund, M; Gachet, C; Lenain, N; Léon, C | 1 |
Cazenave, JP; Freund, M; Gachet, C; Leon, C; Ravanat, C | 1 |
Berkowitz, BA; Luan, H; Roberts, RL | 1 |
Cosi, C; Fluit, P; Gallo-Hendrikx, E; Marien, MR; Martel, JC; Mount, HT; Wu, Y | 1 |
Bartges, JW; Carroll, RC; Cowan, SM; Craft, RM; Gerard, DA; Gompf, RE; Hayes, JR; Moyers, TD; Muenchen, RA; Snider, CC | 1 |
Brockerhoff, SE; Hurley, JB; Taylor, MR; Van Epps, HA | 1 |
Aikawa, K; Maehara, K; Maruyama, Y; Matsumoto, K; Muto, M; Onogi, F; Osugi, T; Saitoh, S; Yaoita, H | 1 |
Casali, EA; Lara, DR; Leke, R; Oses, JP; Portela, LV; Sarkis, JJ; Schmidt, AP; Souza, DO; Wofchuk, S | 1 |
Huang, C; Javadov, S; Karmazyn, M; Kirshenbaum, L | 1 |
Barreto-Chaves, ML; Bonan, CD; Bruno, AN; Freitas Sarkis, JJ; Pochmann, D; Ricachenevsky, FK | 1 |
Haramaki, N; Ikeda, H; Imaizumi, T; Murohara, T; Yasukawa, H; Yokoyama, S | 1 |
Baysan, O; Beyan, C; Coskun, T; Erinç, K; Işik, E; Kaptan, K; Kayir, H; Oztas, Y; Uzbay, T; Uzun, M | 1 |
Alam, HB; Britten-Webb, J; Chen, H; Jaskille, A; Kirkpatrick, JR; Koustova, E; Rhee, P; Valeri, CR | 1 |
Hayashi, K; Kawasaki, T; Miyata, K; Moritani, Y; Saito, T; Takasaki, J; Taniguchi, M; Uchida, W; Uemura, T | 1 |
Helps, SC; Nilsson, M; Sims, NR; Thoren, AE | 1 |
Chaikof, EL; Cui, W; Haller, CA; Robson, SC; Wen, J | 1 |
Akopova, I; Borejdo, J; Dumka, D; Guzman, G; Szczesna-Cordary, D; Talent, J | 1 |
Bardenheuer, HJ; Heller, AR; Koch, T; Plaschke, K; Rothermel, J; Schmeck, J; Weigand, MA; Wendel, M | 1 |
Costa, AD; Dos Santos, P; Garlid, KD; Pasdois, P; Pierre, SV; Quinlan, CL; Rissa, A; Tariosse, L; Vinassa, B | 1 |
Chen, C; El Sayed, HF; Kougias, P; Lin, PH; Okada, T; Rawat, A; Steinberg, JL; Yao, Q; Zhou, W | 1 |
Hayashi, H; Ito, H; Nagamura, Y; Sudo, T; Toga, K; Yamada, Y | 1 |
Kahn, NN; Karmohapatra, SK; Sinha, AK | 1 |
Chan, TO; Feldman, AM; Funakoshi, H; Good, JC; Herrmann, DE; Higuchi, Y; Jackson, EK; Koch, WJ; Lee, LL; Tang, Z; Zacharia, LC; Zhang, J | 1 |
Bostwick, JS; Crain, EJ; Hua, J; Jiang, X; Ogletree, ML; Rehfuss, R; Schumacher, WA; Watson, CA; Wong, PC | 1 |
Bielicki, G; Boirie, Y; Chanseaume, E; Freyssenet, D; Morio, B; Renou, JP; Tardy, AL | 1 |
Emerson, M; Jones, S; Moore, C; Page, CP; Pitchford, SC; Tymvios, C | 1 |
Bergmeier, W; Bernimoulin, M; Dole, VS; Krieger, M; Matuskova, J; Vasile, E; Wagner, DD; Yesilaltay, A | 1 |
Amâncio, RT; Bozza, FA; d'Avila, JC; Galina, A; Oliveira, MF; Santiago, AP | 1 |
Andries, R; Blockeel, E; Bourgain, RH; Jacqueloot, J; Rennies, J; Six, F; Vereecke, F; Vermariën, H | 1 |
Cowley, RA; Kahng, MW; Trifillis, AL; Trump, BF | 1 |
Nordøy, A | 1 |
Hui, SW; Novak, EK; Swank, RT | 1 |
Hirano, T; Manabe, T | 1 |
He, YY; Hsu, CY; Lin, TA; Lin, TN; Sun, GY; Zhang, JP | 1 |
Behm, CA; Bygrave, FL; Somerville, AC | 1 |
Marks, SC; Shalhoub, V; Wisner-Lynch, LA | 1 |
Corsi, M; Ferrero, ME; Gaja, G; Parise, M | 1 |
Frelinger, AL; Lucchesi, BR; Mu, DX; Roncinske, RA; Rote, WE | 1 |
Ledingham, JG; Radda, GK; Raine, AE; Roberts, AF; Seymour, AM | 1 |
Brown, CG; Cody, RJ; Griffith, R; Hoekstra, JW; Kelley, R; Lewis, D; Scheatzle, M | 1 |
Anversa, P; Bianchi, G; Ceppi, E; Cinato, E; Conti, F; Ferrari, P; Torielli, L | 1 |
Kanazawa, T; Onodera, K; Takanashi, S; Yasugahira, H | 1 |
Boss, GR; Hammond, HK; Helmer, GA; McKirnan, MD; Ross, J; Shabetai, R | 1 |
Adams, HR; Gupta, M; Mattox, ML; Myers, PR; Parker, JL; Rogers, S | 1 |
Bernocchi, P; Ceconi, C; Curello, S; Ferrari, R; Pasini, E; Pedersini, P | 1 |
Ko, FN; Kuo, SC; Lee, FY; Teng, CM; Wu, CC | 1 |
Accominotti, M; Borson-Chazot, F; Bost, M; Ciavatti, M; Douillet, C | 1 |
Askew, BC; Baldwin, JJ; Claremon, DA; Cook, JJ; Glass, JD; Gould, RJ; Hartman, GD; Holahan, MA; Lynch, JJ; McIntyre, CJ; Sitko, GR; Stranieri, MT | 1 |
Hughes, WT; Oz, HS | 1 |
Fujiyoshi, T; Katada, J; Muramatsu, M; Takiguchi, Y; Uno, I | 1 |
Alvarez, J; Arias-Diaz, J; Balibrea, JL; del Barrio, R; Garcia-Carreras, C; Gomez, M; Gonzalez, P | 1 |
Bonten, E; d'Azzo, A; Rottier, RJ | 1 |
Brass, LF; Funk, CD; Johnson, EN | 1 |
Aguejouf, O; Belougne-Malfatti, E; Doutremepuich, C; Doutremepuich, F | 1 |
Beyer, ME; Hoffmeister, HM; Kappelmann, A; Seipel, L | 1 |
Blair, PS; Katz, ML; Savill, JD; Siakotos, AN | 1 |
Hoyer, S; Lannert, H | 1 |
Fujimori, H; Narama, I; Nishikawa, T; Nishimura, M; Nomura, S; Ozaki, K; PanHou, H | 1 |
Gready, JE; Harvey, PJ; Hickey, HM; Le Couteur, DG; McLean, AJ | 1 |
Dave, KR; Katyare, SS; Swegert, CV | 1 |
Frese, A; Künnecke, M; Lorenz, W; Opper, C; Rinke, D; Stinner, B; Wesemann, W | 1 |
Bardenheuer, HJ; Martin, E; Michel, A; Plaschke, K; Weigand, MA | 1 |
Asai, F; Naganuma, H; Ogawa, T; Sugidachi, A | 1 |
Asai, F; Inoue, T; Koike, H; Ogawa, T; Sugidachi, A | 1 |
Badimon, JJ; Chesebro, JH; Fuster, V; Rauch, U; Reis, ED; Roqué, M | 1 |
Boczkowska-Radziwon, B; Breddin, HK; Giedrojc, J; Kloczko, J; Radziwon, P; Schenk, J; Wojtukiewicz, MZ | 1 |
Bernat, A; Herbert, JM; Lalé, A; Roque, C; Savi, P; Zamboni, G | 1 |
Aguejouf, O; Belon, P; Doutremepuich, C; Malfatti, E | 1 |
Driscoll, EM; Gonzales, ML; Huang, J; Lucchesi, BR; Park, AM | 1 |
Andersen, SG; Bonifacino, JS; Ciciotte, SL; Dell'Angelica, EC; Eicher, EM; Gwynn, B; Hunter, SJ; Peters, LL; Smith, RS; Swank, RT; Washburn, LL | 1 |
Baurand, A; Cazenave, JP; Freund, M; Gachet, C; Léon, C; Ravanat, C | 1 |
Al-Awadi, FM; Khan, I | 1 |
Ballabeni, V; Barocelli, E; Bondavalli, F; Brullo, C; Bruno, O; Chiavarini, M; Impicciatore, M; Ranise, A; Schenone, S; Tognolini, M | 1 |
Bache, RJ; Godinot, C; Gong, G; Ishibashi, Y; Liu, J; Murakami, Y; Ochiai, K; Prody, C; Wang, C; Zhang, J | 1 |
Borg, J; Lampert, E; Leclerc, N; Poindron, P; Ribera, F; Warter, JM; Zoll, J | 1 |
Feldbaum, VM; Huang, J; Lucchesi, BR; Werns, SW | 1 |
Ballarin, R; Carlucci, F; Gerunda, G; Marinello, E; Merenda, R; Neri, D; Rosi, F; Tabucchi, A | 1 |
Collinson, LM; Copeland, NG; Gautam, R; Jenkins, NA; McGarry, MP; Novak, EK; Reddington, M; Swank, RT | 1 |
Mózsik, G; Vizi, F | 1 |
Sordahl, LA | 1 |
Tygstrup, N | 1 |
Heptinstall, S; White, AM | 1 |
Iglewski, BH; Pavlovskis, OR; Pollack, M | 1 |
Fong, JS; O'Regan, S | 1 |
Dean, BM; Perrett, D; Sensi, M | 1 |
Cunningham, SK; Keaveny, TV | 1 |
Kamiyama, Y; Nambu, H; Ohshita, M; Takeda, H; Yamaoka, Y | 1 |
De Jong, JW; Stam, H | 1 |
Brachfeld, N; Horner, H; Kligfield, P | 1 |
Hughes, HC; Liedtke, AJ; Neely, JR | 1 |
Hossmann, KA; Kleihues, P; Kobayashi, K; Pegg, AE; Zimmermann, V | 1 |
Aubert, D; Ferrand, JC; Lacaze, B; Pepin, O; Thebault, JJ | 1 |
De Jong, JW; Goldstein, S | 1 |
Liedtke, AJ | 1 |
Brooks, RM; Heistad, DD; Kaul, S; Padgett, RC; Waack, BJ | 1 |
Mayhan, WG | 1 |
Behrens-Baumann, W; Scheurer, G; Schroer, H | 1 |
Maruyama, S; Uchiyama, S; Yamazaki, M | 1 |
Chi, LG; Kitzen, JM; Lucchesi, BR; Uprichard, AC | 1 |
Harvey, C; Kitzen, JM; McCallum, JD; Morin, ME | 1 |
Antonaccio, MJ; Buchanan, JO; Fleming, JS; Iben, LG; Yocca, FD | 1 |
Bourgain, RH | 1 |
Ankerst, J; Fäldt, R; Thörne, J; Zoucas, E | 1 |
Corkey, BE; Douglas, SD; Kilpatrick, LE; Polin, RA | 1 |
Bowie, EJ; Daniels, TM; Fass, DN; White, JG | 1 |
Bernat, A; Cazenave, JP; Defreyn, G; Delebassée, D; Gordon, JL; Maffrand, JP | 1 |
Dewar, HA; Griffin, SG; Jones, MR; Marriner, J; Oxley, A | 1 |
Ingerman-Wojenski, CM; Silver, MJ; Smith, M | 1 |
Bianco, R; Einzig, S; Foker, J; Noren, G; St Cyr, J; Staley, N; Wang, TC | 1 |
de Gaetano, G; Dejana, E; Finesso, M; Gorio, A; Languino, LR; Prosdocimi, M; Tessari, F | 1 |
Benedict, CR; Cartwright, J; Mathew, B; Rex, KA; Sordahl, LA | 1 |
Anwer, K | 1 |
Holmin, T; Siesjö, BK; Vang, J | 1 |
Boksay, I; Ganser, V | 1 |
Hohage, R | 1 |
Guckian, JC | 1 |
Kirby, RE; Lassman, HB; Novick, WJ | 1 |
Cepelák, V; Cepeláková, H; Nĕmecek, O; Roubal, Z | 1 |
Gudbjarnason, S; Mathes, P; Ravens, KG | 1 |
Morgan, HE; Neely, JR; Rovetto, MJ; Whitmer, JT | 1 |
Plum, F; Salford, LG; Siesjö, BK | 1 |
Keiding, N; Keiding, S; Tystrup, N | 1 |
Ljunggren, B; Schutz, H; Siesjö, BK | 1 |
Ljunggren, B; Ratcheson, RA; Siesjö, BK | 1 |
Gudbjarnason, S; Mathes, P; Puri, PS | 1 |
Chen, CJ; Chen, SY; Chen, WY; Chiang, AN; Kao, TK; Liao, SL; Ou, YC; Wang, CC | 1 |
3 review(s) available for adenosine diphosphate and Disease Models, Animal
Article | Year |
---|---|
Some biochemical lesions in myocardial disease.
Topics: Actins; Adenosine Diphosphate; Animals; Cardiomegaly; Cardiomyopathies; Coronary Disease; Disease Models, Animal; Dogs; Heart; Heart Failure; Humans; Mitochondria, Heart; Myocardial Contraction; Myocardium; Myosins; Oxygen Consumption; Sarcolemma; Sarcoplasmic Reticulum | 1979 |
Aspects of hepatic hypoxia: observations on the isolated, perfused pig liver.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Galactose; Hypoxia; Liver; Liver Diseases; Oxygen Consumption; Perfusion; Phosphotransferases; Swine | 1975 |
Contribution of platelets to thrombus formation.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Calcium; Collagen; Disease Models, Animal; Endothelium; Epinephrine; Humans; Platelet Aggregation; Serotonin; Thrombin; Thrombosis | 1978 |
257 other study(ies) available for adenosine diphosphate and Disease Models, Animal
Article | Year |
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Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Anti-inflammatory effect of P2Y1 receptor blocker MRS2179 in a rat model of traumatic brain injury.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Behavior, Animal; Brain Injuries, Traumatic; Cerebral Cortex; Disease Models, Animal; Galectin 3; Microglia; Neuroinflammatory Diseases; Purinergic P2Y Receptor Antagonists; Rats | 2022 |
Anshen Dingzhi prescription in the treatment of PTSD in mice: Investigation of the underlying mechanism from the perspective of hippocampal synaptic function.
Topics: Adenosine Diphosphate; Animals; Disease Models, Animal; Hippocampus; Mice; Stress Disorders, Post-Traumatic; TOR Serine-Threonine Kinases | 2022 |
Aspirin Administration Mitigates Platelet Hyperaggregability After Splenectomy in a Murine Model.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Disease Models, Animal; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Splenectomy | 2022 |
Activation of P2Y1R impedes intestinal mucosa repair during colitis.
Topics: Adenosine Diphosphate; Animals; Caco-2 Cells; Colitis; Dextran Sulfate; Disease Models, Animal; Humans; Inflammation; Inflammatory Bowel Diseases; Intestinal Mucosa; Mice; Mice, Inbred C57BL | 2023 |
Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Heart Diseases; Mice; Mice, Knockout; Myocytes, Cardiac; Protein Serine-Threonine Kinases; Signal Transduction; Thyroxine; TOR Serine-Threonine Kinases | 2019 |
The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function.
Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Constriction; Disease Models, Animal; Gene Expression Regulation; Hepatic Artery; Hormesis; Liver Failure; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; Oxygen Consumption; Phosphorylation; Portal Vein; Premedication; Pyrimidines; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Solubility; Thiophenes | 2020 |
e5NT inhibitor protects acute restraint stress-induced depression by regulating nucleoside release in mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Elevated Plus Maze Test; Enzyme Inhibitors; Exploratory Behavior; GPI-Linked Proteins; Hippocampus; Male; Mice; Open Field Test; Restraint, Physical; Stress, Psychological; Uridine | 2020 |
Inhibition of ecto-5'-nucleotidase and adenosine deaminase is able to reverse long-term behavioural effects of early ethanol exposure in zebrafish (Danio rerio).
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Animals; Antisocial Personality Disorder; Behavior, Animal; Disease Models, Animal; Ethanol; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Social Interaction; Zebrafish | 2020 |
Cardiac expression and location of hexokinase changes in a mouse model of pure creatine deficiency.
Topics: Adenosine Diphosphate; Adenylate Kinase; Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Cell Respiration; Creatine; Creatine Kinase; Developmental Disabilities; Disease Models, Animal; Energy Metabolism; Female; Guanidinoacetate N-Methyltransferase; Hexokinase; Intellectual Disability; Language Development Disorders; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Movement Disorders; Myocytes, Cardiac; Speech Disorders | 2021 |
Mitochondrial uncoupler MB1-47 is efficacious in treating hepatic metastasis of pancreatic cancer in murine tumor transplantation models.
Topics: Adenocarcinoma; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Disease Models, Animal; Glucose; Glycolysis; Heterografts; Humans; Liver Neoplasms; Mice; Mitochondria; Pyruvic Acid | 2021 |
Cerebral and myocardial mitochondrial injury differ in a rat model of cardiac arrest and cardiopulmonary resuscitation.
Topics: Adenosine Diphosphate; Animals; Brain; Calcium; Cardiopulmonary Resuscitation; Disease Models, Animal; Electron Transport Chain Complex Proteins; Heart Arrest; Male; Mitochondria; Mitochondrial Permeability Transition Pore; Myocardium; Oxygen Consumption; Rats, Sprague-Dawley | 2021 |
A peptide derived from apoptin inhibits glioma growth.
Topics: Adenosine Diphosphate; Animals; Antineoplastic Agents; Apoptosis; Capsid Proteins; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Gene Expression; Glioma; HSP70 Heat-Shock Proteins; Humans; Mice; Models, Molecular; Peptides; Protein Conformation; Xenograft Model Antitumor Assays | 2017 |
STAT3 balances myocyte hypertrophy vis-à-vis autophagy in response to Angiotensin II by modulating the AMPKα/mTOR axis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Angiotensin II; Animals; Autophagy; Disease Models, Animal; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Hypertrophy; Myocytes, Cardiac; Pyridines; Rats; Signal Transduction; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Tyrphostins | 2017 |
Adenosine Production by Biomaterial-Supported Mesenchymal Stromal Cells Reduces the Innate Inflammatory Response in Myocardial Ischemia/Reperfusion Injury.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Enzyme Inhibitors; GPI-Linked Proteins; Humans; Hydrogen Peroxide; Immunity, Innate; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Rats, Sprague-Dawley; Recovery of Function; Stem Cell Niche; Tissue Scaffolds | 2018 |
Indole-3-carbinol improves neurobehavioral symptoms in a cerebral ischemic stroke model.
Topics: Adenosine Diphosphate; Animals; Behavior, Animal; Carrageenan; Cerebrovascular Circulation; Disease Models, Animal; Fibrinolytic Agents; Humans; Indoles; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Platelet Aggregation; Rats, Wistar; Thrombosis | 2018 |
Synthesis of a Novel Series of Amino Acid Prodrugs Based on Thienopyridine Scaffolds and Evaluation of Their Antiplatelet Activity.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Clopidogrel; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Molecular Structure; Platelet Aggregation; Prasugrel Hydrochloride; Prodrugs; Rats; Thienopyridines; Ticlopidine | 2018 |
P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model.
Topics: Adenosine Diphosphate; Alzheimer Disease; Animals; Astrocytes; Cognition; Disease Models, Animal; Hippocampus; Humans; Memory; Mice, Transgenic; Nerve Net; Neurons; Plaque, Amyloid; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Signal Transduction; Synapses | 2018 |
ENERGY PROFILE OF RATS WITH OVERACTIVE BLADDER SYNDROME PHARMACOLOGICALLY CORRECTED WITH QUERCETIN.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Administration, Oral; Animals; Antioxidants; Chromatography, High Pressure Liquid; Disease Models, Animal; Erythrocytes; Female; Male; Quercetin; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder, Overactive | 2018 |
A comparison of LKB1/AMPK/mTOR metabolic axis response to global ischaemia in brain, heart, liver and kidney in a rat model of cardiac arrest.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Brain; Disease Models, Animal; Electrocardiography; Heart Arrest; Ischemia; Kidney; Liver; Myocardium; Organ Specificity; Phosphorylation; Protein Serine-Threonine Kinases; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases | 2018 |
Plasma Phospholipid Transfer Protein Promotes Platelet Aggregation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Membrane; Cells, Cultured; Cerebral Infarction; Collagen; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Phosphatidylserines; Phospholipid Transfer Proteins; Platelet Aggregation; Thrombin; Thrombophilia | 2018 |
Context-Specific Switch from Anti- to Pro-epileptogenic Function of the P2Y
Topics: Adenosine Diphosphate; Animals; Brain; Deoxyadenine Nucleotides; Disease Models, Animal; Electroencephalography; Epilepsy; Male; Mice, Inbred C57BL; Mice, Knockout; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Status Epilepticus | 2019 |
Combination therapy using fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes and hemoglobin vesicles for trauma-induced massive hemorrhage in thrombocytopenic rabbits.
Topics: Adenosine Diphosphate; Animals; Blood Substitutes; Disease Models, Animal; Drug Therapy, Combination; Fibrinogen; Hemoglobins; Hemorrhage; Liposomes; Oligopeptides; Rabbits; Wounds and Injuries | 2019 |
Increased glucagon-like peptide-1 secretion may be involved in antidiabetic effects of ginsenosides.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Line; Cells, Cultured; Diabetes Mellitus, Experimental; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Tract; Ginsenosides; Glucagon-Like Peptide 1; Glucose; Homeostasis; Humans; Hypoglycemic Agents; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Saponins; Streptozocin | 2013 |
Synergetic neuroprotection of normobaric oxygenation and ethanol in ischemic stroke through improved oxidative mechanism.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Combined Modality Therapy; Disease Models, Animal; Ethanol; Neuroprotective Agents; Oxygen Inhalation Therapy; Rats; Reactive Oxygen Species; Stroke; Treatment Outcome | 2013 |
Cardioprotection via preserved mitochondrial structure and function in the mPer2-mutant mouse myocardium.
Topics: Adenosine Diphosphate; Animals; Apoptosis; Biomarkers; Blotting, Western; Disease Models, Animal; Female; Immunohistochemistry; Macrophages; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondria, Heart; Mitochondrial Membranes; Mutation; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Neutrophil Infiltration; Oxidative Stress; Oxygen Consumption; Period Circadian Proteins; Reactive Oxygen Species | 2013 |
Unchanged mitochondrial organization and compartmentation of high-energy phosphates in creatine-deficient GAMT-/- mouse hearts.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Creatine; Creatine Kinase; Disease Models, Animal; Energy Metabolism; Female; Genotype; Guanidinoacetate N-Methyltransferase; Homeostasis; Kinetics; Language Development Disorders; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Microscopy, Fluorescence; Mitochondria, Heart; Models, Cardiovascular; Movement Disorders; Myocytes, Cardiac; Phenotype; Pyruvate Kinase | 2013 |
Extract of Ulmus macrocarpa Hance prevents thrombus formation through antiplatelet activity.
Topics: Adenosine Diphosphate; Animals; Catechin; Chromatography, High Pressure Liquid; Collagen; Disease Models, Animal; Fibrinolytic Agents; Male; Plant Extracts; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thrombosis; Ulmus | 2013 |
Depressed Frank-Starling mechanism in the left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T deletion mutation ΔK210.
Topics: Adenosine Diphosphate; Animals; Calcium; Cardiomyopathy, Dilated; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Heart Ventricles; In Vitro Techniques; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Sequence Deletion; Troponin T | 2013 |
Disruption in connexin-based communication is associated with intracellular Ca²⁺ signal alterations in astrocytes from Niemann-Pick type C mice.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Antibodies; Astrocytes; Calcium; Calcium Signaling; Cell Communication; Cells, Cultured; Connexin 43; Connexins; Disease Models, Animal; Gap Junctions; Gene Deletion; Gene Expression Regulation; Hippocampus; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Proteins; Receptors, Purinergic P2Y1; Tissue Culture Techniques | 2013 |
Antiplatelet loading improves behavioral outcome in a rabbit model of stroke.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Brain Ischemia; Collagen; Disease Models, Animal; Embolization, Therapeutic; Fibrinolytic Agents; Male; Platelet Aggregation Inhibitors; Rabbits; Random Allocation; Treatment Outcome | 2013 |
Red cell-derived microparticles (RMP) as haemostatic agent.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation Disorders; Busulfan; Cell Separation; Cell-Derived Microparticles; Clopidogrel; Disease Models, Animal; Erythrocytes; Flow Cytometry; Hemostasis; Humans; Male; Platelet Aggregation; Rabbits; Rats; Rats, Sprague-Dawley; Thrombelastography; Thrombin; Thrombocytopenia; Thromboplastin; Ticlopidine | 2013 |
Proteasome proteolysis supports stimulated platelet function and thrombosis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell-Derived Microparticles; Chlorides; Cytoskeletal Proteins; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Filamins; Humans; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Transfusion; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Talin; Thrombin; Thrombosis; Time Factors; Ubiquitination | 2014 |
Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain.
Topics: Acids; Acrylamides; Adenosine Diphosphate; Animals; Benzophenanthridines; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Diterpenes; Hindlimb; Hot Temperature; Hyperalgesia; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Injections; Ion Channels; Ischemia; Pain; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Sodium Chloride; Thrombosis; Tissue Extracts; TRPV Cation Channels | 2014 |
The molecular mechanisms affecting N-acetylaspartate homeostasis following experimental graded traumatic brain injury.
Topics: Acetyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Amidohydrolases; Animals; Aspartic Acid; Brain; Brain Injuries; Disease Models, Animal; Male; Mitochondria; Phosphorylation; Rats; Rats, Wistar | 2014 |
Anti-platelet therapy with clopidogrel prevents endothelial dysfunction and vascular remodeling in aortas from hypertensive rats.
Topics: Adenosine Diphosphate; Animals; Aorta; Blood Pressure; Clopidogrel; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Hypertension; Male; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Rats; Receptors, Purinergic P2Y; Thionucleotides; Ticlopidine; Vascular Remodeling; Vasoconstriction; Vasodilation | 2014 |
Plasma ATP is required for neutrophil activation in a mouse sepsis model.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Male; Mice, Inbred C57BL; Neutrophil Activation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Sepsis; Suramin | 2014 |
Comparison of the effect of coagulation and platelet function impairments on various mouse bleeding models.
Topics: Adenosine Diphosphate; Animals; Antibodies; Anticoagulants; Arteries; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Disease Models, Animal; Dose-Response Relationship, Drug; Hemorrhage; Heparin; Male; Mice, Inbred C57BL; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Saphenous Vein; Tail | 2014 |
mTOR pathway is involved in ADP-evoked astrocyte activation and ATP release in the spinal dorsal horn in a rat neuropathic pain model.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Disease Models, Animal; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; Neuralgia; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Dorsal Horn; TOR Serine-Threonine Kinases | 2014 |
Integrated autofluorescence characterization of a modified-diet liver model with accumulation of lipids and oxidative stress.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diet; Disease Models, Animal; Glutathione; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Spectrometry, Fluorescence; Thiobarbituric Acid Reactive Substances; Vitamin A | 2014 |
SAR216471, an alternative to the use of currently available P2Y₁₂ receptor inhibitors?
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Binding, Competitive; Biological Availability; Blood Platelets; CHO Cells; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hemorrhage; Humans; Indoles; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding; Purinergic P2Y Receptor Antagonists; Pyridazines; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction; Thionucleotides; Thrombosis; Transfection | 2014 |
Alterations in enterocyte mitochondrial respiratory function and enzyme activities in gastrointestinal dysfunction following brain injury.
Topics: Adenosine Diphosphate; Animals; Brain Injuries; Cell Respiration; Disease Models, Animal; Down-Regulation; Electron Transport Chain Complex Proteins; Energy Metabolism; Enterocytes; Gastrointestinal Diseases; Intestine, Small; Male; Mitochondria; Oxygen; Rats, Sprague-Dawley; Time Factors | 2014 |
RhoA/ROCK pathway mediates p38 MAPK activation and morphological changes downstream of P2Y12/13 receptors in spinal microglia in neuropathic pain.
Topics: Adenosine Diphosphate; Animals; Calcium-Binding Proteins; Disease Models, Animal; Enzyme Inhibitors; Hyperalgesia; Male; Microfilament Proteins; Microglia; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain Threshold; Phosphorylation; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y; rhoA GTP-Binding Protein; Signal Transduction; Spinal Cord; Spinal Cord Injuries; Thionucleotides | 2015 |
Disabled-2 is required for efficient hemostasis and platelet activation by thrombin in mice.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Diphosphate; Animals; Disease Models, Animal; DNA-Binding Proteins; Hemostasis; Mice; Mice, Knockout; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Thrombin; Thrombosis; TOR Serine-Threonine Kinases | 2014 |
Nrf2-ARE activator carnosic acid decreases mitochondrial dysfunction, oxidative damage and neuronal cytoskeletal degradation following traumatic brain injury in mice.
Topics: Abietanes; Adenosine Diphosphate; Aldehydes; Analysis of Variance; Animals; Antioxidants; Brain; Brain Injuries; Cytoskeleton; Disease Models, Animal; Dose-Response Relationship, Drug; Lipid Peroxidation; Male; Mice; Mitochondrial Diseases; Oxidative Stress; Plant Extracts; Succinic Acid | 2015 |
RhoA signaling through platelet P2Y₁ receptor controls leukocyte recruitment in allergic mice.
Topics: Adenosine Diphosphate; Allergens; Animals; Blood Platelets; Chemokines; Chemotaxis, Leukocyte; Disease Models, Animal; Female; Hypersensitivity; Leukocytes; Lung; Macrophages; Mice; Models, Biological; Ovalbumin; P-Selectin; Platelet Aggregation; Purinergic P2Y Receptor Agonists; Receptors, Purinergic P2Y1; rhoA GTP-Binding Protein; Signal Transduction | 2015 |
Defective release of α granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models.
Topics: Adaptor Protein Complex 3; Adenosine Diphosphate; Animals; Blood Platelets; Carrier Proteins; Cell Degranulation; Disease Models, Animal; Guanine Nucleotide Exchange Factors; Hermanski-Pudlak Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Lectins; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Secretory Vesicles; SNARE Proteins; Thrombin; Thrombosis; Vesicular Transport Proteins | 2015 |
A novel role of Eruca sativa Mill. (rocket) extract: antiplatelet (NF-κB inhibition) and antithrombotic activities.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Brassicaceae; Chemokine CCL5; Disease Models, Animal; Fibrinolytic Agents; Humans; Interleukin-1beta; Mice; Mice, Inbred C57BL; NF-kappa B; P-Selectin; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Thromboxane B2; Transforming Growth Factor beta1 | 2014 |
DMT1-mutant erythrocytes have shortened life span, accelerated glycolysis and increased oxidative stress.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anemia, Hypochromic; Animals; Apoptosis; Cation Transport Proteins; Disease Models, Animal; Erythrocytes; Erythropoiesis; Glycolysis; Humans; Mice; Mutation; Oxidative Stress; Reactive Oxygen Species | 2014 |
Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome.
Topics: Adenosine Diphosphate; Animals; Apyrase; Blood Platelets; Cell Degranulation; Disease Models, Animal; Endothelial Cells; Exocytosis; Female; Fibrin; Hermanski-Pudlak Syndrome; Human Umbilical Vein Endothelial Cells; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Aggregation; Protein Disulfide-Isomerases; RNA, Small Interfering; Thrombin; Thrombosis; Vesicular Transport Proteins | 2015 |
A Novel Direct Factor Xa Inhibitory Peptide with Anti-Platelet Aggregation Activity from Agkistrodon acutus Venom Hydrolysates.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Agkistrodon; Amino Acid Sequence; Animals; Anticoagulants; Blood Coagulation Tests; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Female; Hydrolysis; Male; Mice; Molecular Weight; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Snake Venoms; Thrombosis | 2015 |
Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Chlorides; Disease Models, Animal; Enzyme Activation; Ferric Compounds; Fibrinolytic Agents; Gene Expression Regulation; Heme Oxygenase-1; Humans; Lactates; Microfilament Proteins; Models, Biological; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Disulfide-Isomerases; Proteomics; Rats; Thrombosis; Venous Thrombosis | 2015 |
Oxidative metabolism in YAC128 mouse model of Huntington's disease.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Brain; Disease Models, Animal; Energy Metabolism; Gene Expression; Humans; Huntingtin Protein; Huntington Disease; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Mitochondria; Mutation; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Phenotype; Synapses | 2015 |
Platelet PI3Kγ Contributes to Carotid Intima-Media Thickening under Severely Reduced Flow Conditions.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Carotid Artery Diseases; Cell Adhesion; Cell Communication; Chemotaxis, Leukocyte; Class Ib Phosphatidylinositol 3-Kinase; Cytokines; Disease Models, Animal; Endothelial Cells; Gene Expression; Hemodynamics; Inflammation Mediators; Leukocytes; Male; Mice; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Proto-Oncogene Proteins c-akt; Tunica Intima | 2015 |
Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apolipoproteins E; Apyrase; Atherosclerosis; Blood Flow Velocity; Blood Platelets; Dietary Fats; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Human Umbilical Vein Endothelial Cells; Humans; Kruppel-Like Transcription Factors; Mice; Mice, Knockout; Plaque, Atherosclerotic; Platelet Activation; Response Elements; Shear Strength | 2015 |
Preventive Effect of Aspirin Eugenol Ester on Thrombosis in κ-Carrageenan-Induced Rat Tail Thrombosis Model.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Carrageenan; Disease Models, Animal; Erythrocyte Count; Erythrocytes; Eugenol; Fibrinogen; Hemoglobins; Male; Platelet Aggregation Inhibitors; Platelet Count; Prothrombin Time; Rats; Rats, Wistar; Thrombosis | 2015 |
Pharmacokinetic Properties of Single and Repeated Injection of Liposomal Platelet Substitute in a Rat Model of Red Blood Cell Transfusion-Induced Dilutional Thrombocytopenia.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Blood Platelets; Blood Substitutes; Disease Models, Animal; Erythrocyte Transfusion; Liposomes; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Thrombocytopenia | 2015 |
Platelets promote cartilage repair and chondrocyte proliferation via ADP in a rodent model of osteoarthritis.
Topics: Adenosine Diphosphate; Animals; Biocatalysis; Blood Platelets; Bone Morphogenetic Protein 7; Cartilage, Articular; Cell Proliferation; Cells, Cultured; Chondrocytes; Cluster Analysis; Coculture Techniques; Cyclin B1; Cyclin-Dependent Kinases; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Male; Osteoarthritis; Platelet-Rich Plasma; Rats; Signal Transduction; Wound Healing | 2016 |
Inhibitory effect of caffeic acid on ADP-induced thrombus formation and platelet activation involves mitogen-activated protein kinases.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Platelets; Caffeic Acids; Cell-Derived Microparticles; Cyclic AMP; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis | 2015 |
Prasugrel reduces ischaemic infarct volume and ameliorates neurological deficits in a non-human primate model of middle cerebral artery thrombosis.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Haplorhini; Hemorrhage; Infarction, Middle Cerebral Artery; Macaca fascicularis; Male; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Stroke; Thrombosis; Time Factors | 2015 |
Purinergic P2Y12 Receptor Activation in Eosinophils and the Schistosomal Host Response.
Topics: Adenosine Diphosphate; Animals; Bone Marrow Cells; Cell Survival; Collagen; Disease Models, Animal; Eosinophil Peroxidase; Eosinophils; Humans; Inflammation; Interleukin-13; Interleukin-4; Liver; Mice; Mice, Inbred C57BL; Receptors, Purinergic P2Y12; Schistosoma mansoni; Schistosomiasis mansoni; Th2 Cells | 2015 |
The Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic Activity.
Topics: Adenosine Diphosphate; Animals; Disease Models, Animal; Flow Cytometry; Indoles; Leukocytes; Mice; Mice, Inbred BALB C; Oligopeptides; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Tetradecanoylphorbol Acetate; Thrombosis | 2015 |
Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adult; Animals; Aspirin; Blood Coagulation; Blood Platelets; Coronary Thrombosis; Dinucleoside Phosphates; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Female; Fibrinolytic Agents; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Time Factors; Young Adult | 2016 |
Increased expression of NTPDases 2 and 3 in mesenteric endothelial cells during schistosomiasis favors leukocyte adhesion through P2Y1 receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Cell Adhesion; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Endothelial Cells; Host-Pathogen Interactions; Humans; Hydrolysis; Leukocytes; Male; Mesentery; Mice; Phenotype; Purinergic P2Y Receptor Agonists; Receptors, Purinergic P2Y1; Schistosoma mansoni; Schistosomiasis; Signal Transduction; Up-Regulation | 2016 |
Fibrinogen γ-Chain Peptide-Coated Adenosine 5' Diphosphate-Encapsulated Liposomes Rescue Mice From Lethal Blast Lung Injury via Adenosine Signaling.
Topics: Adenosine; Adenosine Diphosphate; Animals; Blast Injuries; Disease Models, Animal; Fibrinogen; Liposomes; Lung Injury; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Platelet Aggregation Inhibitors; Signal Transduction | 2016 |
NADPH oxidase is implicated in the pathogenesis of oxidative phosphorylation dysfunction in mice fed a high-fat diet.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Deoxyguanosine; Diet, High-Fat; Disease Models, Animal; DNA Damage; ERRalpha Estrogen-Related Receptor; Gene Expression; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NADPH Oxidase 2; Non-alcoholic Fatty Liver Disease; Oxidative Phosphorylation; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptors, Estrogen | 2016 |
Effect of Cardiovascular Injury on Catabolism of Adenosine and Adenosine 5-'Triphosphate in Systemic Blood in a Freely Moving Rat Model In Vivo.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiovascular Diseases; Disease Models, Animal; Hypoxanthine; Isoproterenol; Rats; Rats, Sprague-Dawley; Uric Acid | 2016 |
Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Cell Separation; Disease Models, Animal; Homeostasis; Immunohistochemistry; Male; Meninges; Migraine Disorders; Nucleotides; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Purinergic; Trigeminal Ganglion | 2016 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Arterial Occlusive Diseases; Blood Coagulation; Bone Marrow Transplantation; Chlorides; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hydrolysis; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Monocytes; Phenotype; Platelet Activation; Thrombosis; Time Factors; Transfection | 2016 |
Sustained activation of ADP/P2ry12 signaling induces SMC senescence contributing to thoracic aortic aneurysm/dissection.
Topics: Adenosine Diphosphate; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Biopsy; Cellular Senescence; Cytokines; Disease Models, Animal; Inflammation; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Receptors, Purinergic P2Y12; Signal Transduction; Stress, Mechanical; Ultrasonography | 2016 |
Characterization of the Anticoagulant and Antithrombotic Properties of the Sphingosine 1-Phosphate Mimetic FTY720.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arteriovenous Shunt, Surgical; Biomimetic Materials; Blood Platelets; Carotid Artery, Common; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Fingolimod Hydrochloride; Humans; Lysophospholipids; Male; Platelet Aggregation; Platelet Function Tests; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Thrombosis; Vena Cava, Inferior | 2017 |
Trimetazidine attenuates pressure overload-induced early cardiac energy dysfunction via regulation of neuropeptide Y system in a rat model of abdominal aortic constriction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta, Abdominal; Arterial Pressure; Cardiovascular Agents; Constriction; Disease Models, Animal; Energy Metabolism; Gene Expression Regulation; Hypertrophy, Left Ventricular; Male; Myocardium; Neuropeptide Y; Oxidative Stress; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Receptors, Neuropeptide Y; Signal Transduction; Trimetazidine; Ventricular Function, Left; Ventricular Remodeling | 2016 |
Thrombocytopathy leading to impaired in vivo haemostasis and thrombosis in platelet type von Willebrand disease.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Collagen; Disease Models, Animal; Genetic Predisposition to Disease; Hemostasis; Humans; Kinetics; Mice, Transgenic; Mutation; Phenotype; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Signal Transduction; Thrombin; Thrombosis; von Willebrand Diseases | 2017 |
Role of homocysteine and folic acid on the altered calcium homeostasis of platelets from rats with biliary cirrhosis.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Bile Ducts; Blood Platelets; Calcium; Calcium Signaling; Cholestasis; Disease Models, Animal; Folic Acid; Homocysteine; Ligation; Liver Cirrhosis, Biliary; Male; Platelet Aggregation; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thrombin | 2017 |
Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling.
Topics: Adenosine Diphosphate; Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Body Weight; Cerebrovascular Circulation; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurovascular Coupling; Nitric Oxide; Nitric Oxide Synthase Type I; Presenilin-1; Signal Transduction; tau Proteins | 2017 |
Purinergic enzymatic activities in lymphocytes and cardiomyocytes of mice acutely infected by Trypanosoma cruzi modulating the inflammatory responses.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Chagas Disease; Disease Models, Animal; Female; Heart; Hematologic Tests; Hydrolysis; Lymphocytes; Mice; Myocardium; Myocytes, Cardiac; Parasitemia; Purines; Trypanosoma cruzi | 2017 |
Receptor-interacting protein kinase 3 promotes platelet activation and thrombosis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Disease Models, Animal; Gene Expression; Hemostasis; Humans; Mice; Mice, Knockout; Phosphatidylserines; Phosphorylation; Platelet Activation; Platelet Aggregation; Proto-Oncogene Proteins c-akt; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Thrombin; Thrombosis; Thromboxane A2 | 2017 |
Status epilepticus induces a particular microglial activation state characterized by enhanced purinergic signaling.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Movement; Cell Proliferation; CX3C Chemokine Receptor 1; Cytokines; Disease Models, Animal; Electroencephalography; Fluoresceins; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Organic Chemicals; Patch-Clamp Techniques; Purines; Receptors, Chemokine; Receptors, Purinergic; RNA, Messenger; Signal Transduction; Status Epilepticus; Thionucleotides; Time Factors; Up-Regulation | 2008 |
Ischemia-driven expression of CD73 confers tissue protection during liver ischemia/reperfusion.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Disease Models, Animal; Extracellular Fluid; Liver; Mice; Mice, Knockout; Reperfusion Injury | 2008 |
Myocardial overexpression of adenine nucleotide translocase 1 ameliorates diabetic cardiomyopathy in mice.
Topics: Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomyopathies; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Hyperglycemia; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; RNA, Messenger; Streptozocin | 2009 |
Association between the efficacy of dual antiplatelet therapy and the development of in-stent neointimal hyperplasia in porcine coronary arteries.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Animals; Aspirin; Cell Proliferation; Clopidogrel; Collagen; Coronary Angiography; Coronary Stenosis; Coronary Vessels; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Fibrin; Hyperplasia; Inflammation Mediators; Metals; P-Selectin; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prosthesis Design; Stents; Swine; Ticlopidine; Time Factors; Tunica Intima | 2008 |
Effect of blocking platelet activation with AZD6140 on development of abdominal aortic aneurysm in a rat aneurysmal model.
Topics: Adenosine; Adenosine Diphosphate; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Platelets; Disease Models, Animal; Disease Progression; Elastic Tissue; Guinea Pigs; Inflammation; Male; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Rats; Rats, Inbred Lew; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Ticagrelor; Time Factors; Transplantation, Heterologous | 2009 |
Loss of purinergic vascular regulation in the colon during colitis is associated with upregulation of CD39.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Antigens, Differentiation; Apyrase; Arterioles; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Macrophages; Male; Mice; RNA, Messenger; Splanchnic Circulation; Submucous Plexus; Sympathetic Nervous System; Up-Regulation; Vasoconstriction | 2009 |
P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo.
Topics: Adenosine Diphosphate; Androstadienes; Animals; Apoptosis; Astrocytes; Brain Injuries; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gliosis; Male; MAP Kinase Signaling System; Nucleus Accumbens; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thionucleotides; Up-Regulation; Wortmannin | 2009 |
Clopidogrel versus prasugrel in rabbits. Effects on thrombosis, haemostasis, platelet function and response variability.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Binding, Competitive; Bleeding Time; Clopidogrel; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hemorrhage; Hemostasis; Male; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides; Thiophenes; Thrombosis; Ticlopidine | 2009 |
Rapid cooling preserves the ischaemic myocardium against mitochondrial damage and left ventricular dysfunction.
Topics: Adenosine Diphosphate; Animals; Bedding and Linens; Calcium; Disease Models, Animal; Hemodynamics; Hypothermia, Induced; Liquid Ventilation; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Contraction; Myocardial Ischemia; Myocardium; Rabbits; Reperfusion Injury; Time Factors; Ventricular Dysfunction, Left | 2009 |
Clinically relevant concentrations of dopamine do not amplify agonist-induced human platelet Ca2+ mobilization or GP IIb IIIa activation and do not accelerate acute coronary thrombosis in dogs.
Topics: Acute Disease; Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cardiotonic Agents; Cells, Cultured; Coronary Thrombosis; Disease Models, Animal; Dogs; Dopamine; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin | 2009 |
Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo.
Topics: Adenosine Diphosphate; Animals; Arterioles; Blood Coagulation; Blood Coagulation Disorders; Blood Platelets; Cytoplasmic Granules; Disease Models, Animal; Hermanski-Pudlak Syndrome; Humans; Lasers; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Platelet Aggregation; R-SNARE Proteins; SNARE Proteins | 2009 |
Association of intramyocardial high energy phosphate concentrations with quantitative measures of the ventricular fibrillation electrocardiogram waveform.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biopsy; Disease Models, Animal; Electrocardiography; Energy Metabolism; Myocardium; Severity of Illness Index; Swine; Ventricular Fibrillation | 2009 |
Time-course changes in ectonucleotidase activities during experimental autoimmune encephalomyelitis.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Cell Membrane; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Multiple Sclerosis; Rats; Rats, Inbred Strains; Spinal Cord; Time Factors | 2009 |
Z-ligustilide extracted from Radix Angelica Sinensis decreased platelet aggregation induced by ADP ex vivo and arterio-venous shunt thrombosis in vivo in rats.
Topics: 4-Butyrolactone; Adenosine Diphosphate; Angelica sinensis; Animals; Blood Coagulation; Depression, Chemical; Disease Models, Animal; Drugs, Chinese Herbal; Male; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Thrombosis | 2009 |
ADP-degrading enzymes inhibit platelet activation in bile duct-ligated rats.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Alkaline Phosphatase; Animals; Bile Ducts; Blood Platelets; Cholestasis; Collagen; Disease Models, Animal; Humans; Ligation; Platelet Aggregation; Platelet Count; Rats; Rats, Wistar; Time Factors | 2010 |
Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Calcium; Diabetes Mellitus, Type 2; Disease Models, Animal; DNA, Mitochondrial; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Membrane Potentials; Mice; Mice, Inbred Strains; Mice, Transgenic; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Ribosomal | 2010 |
L-4F alters hyperlipidemic (but not healthy) mouse plasma to reduce platelet aggregation.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Animals; Apolipoprotein A-I; Apolipoproteins E; Arachidonic Acid; Blood Coagulation; Collagen; Dinoprostone; Disease Models, Animal; Hyperlipidemias; Injections, Subcutaneous; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin D2; Receptors, LDL; Thromboxane A2 | 2010 |
A new role for the A2b adenosine receptor in regulating platelet function.
Topics: Adenosine A2 Receptor Agonists; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Platelets; Cells, Cultured; Cyclic AMP; Disease Models, Animal; Femoral Artery; Genotype; Inflammation; Lipopolysaccharides; Megakaryocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Platelet Aggregation; Receptor, Adenosine A2B; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA, Messenger; Time Factors; Up-Regulation | 2010 |
Platelet adhesion and intracellular calcium levels in antigen-challenged rats.
Topics: Adenosine Diphosphate; Animals; Bronchoalveolar Lavage Fluid; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinogen; Immunoglobulin E; Inflammation; Lung; Male; Ovalbumin; Platelet Adhesiveness; Rats; Rats, Wistar; Thrombin; Thrombocytopenia; Time Factors | 2010 |
Effect of ketogenic diet on nucleotide hydrolysis and hepatic enzymes in blood serum of rats in a lithium-pilocarpine-induced status epilepticus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Convulsants; Diet, Ketogenic; Disease Models, Animal; Enzymes; Female; Hydrolysis; Lithium; Liver; Nucleotides; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2010 |
Pharmacodynamic and pharmacokinetic evaluation of clopidogrel and the carboxylic acid metabolite SR 26334 in healthy dogs.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Blood Platelets; Carboxylic Acids; Clopidogrel; Cytochrome P-450 Enzyme System; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Ticlopidine | 2010 |
Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS.
Topics: Adenosine Diphosphate; Amyotrophic Lateral Sclerosis; Animals; Calcium; Disease Models, Animal; Electric Conductivity; Humans; Lipid Bilayers; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membranes; Mutation, Missense; Paralysis; Protein Folding; Rats; Rats, Transgenic; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Voltage-Dependent Anion Channel 1 | 2010 |
A new function for ATP: activating cardiac sympathetic afferents during myocardial ischemia.
Topics: Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic Fibers; Animals; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart; Male; Myocardial Ischemia; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Sensory Receptor Cells; Signal Transduction; Spinal Nerves; Time Factors | 2010 |
Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion.
Topics: Adenosine Diphosphate; Animals; Calcium; Cell Respiration; Cyclic S-Oxides; Cyclophilins; Cyclosporine; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Peptidyl-Prolyl Isomerase F; Phosphorylation; Rats; Rats, Inbred Lew; STAT3 Transcription Factor | 2010 |
Chronic stress sensitizes rats to pancreatitis induced by cerulein: role of TNF-α.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Amylases; Animals; Antibodies; Calcium Signaling; Caspases; Ceruletide; Cholecystokinin; Chronic Disease; Cytoskeleton; Disease Models, Animal; Enzyme Activation; Lung Injury; Male; Necrosis; NF-kappa B; Pancreas, Exocrine; Pancreatitis; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Restraint, Physical; Severity of Illness Index; Stress, Psychological; Tissue Culture Techniques; Trypsin; Tumor Necrosis Factor-alpha | 2010 |
A highly constrained cyclic (S,S)-CDC- peptide is a potent inhibitor of carotid artery thrombosis in rabbits.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Arachidonic Acid; Bleeding Time; Blood Coagulation; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Collagen; Disease Models, Animal; Electric Stimulation; Eptifibatide; Humans; Male; Molecular Sequence Data; Peptides; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombosis | 2011 |
Sequence of cellular events in pancreatic islets leading to impaired insulin secretion in chronic kidney disease.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Body Weight; Calcium-Transporting ATPases; Creatinine; Disease Models, Animal; Insulin; Insulin Secretion; Islets of Langerhans; Kidney Failure, Chronic; Male; Parathyroid Hormone; Potassium Channels; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase | 2011 |
The periodontal anaerobe Porphyromonas gingivalis induced platelet activation and increased aggregation in whole blood by rat model.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Disease Models, Animal; Fibrinogen; Flow Cytometry; Humans; Male; P-Selectin; Periodontitis; Platelet Activation; Platelet Aggregation; Porphyromonas gingivalis; Rats; Rats, Wistar | 2011 |
Transplanted human cord blood-derived unrestricted somatic stem cells preserve high-energy reserves at the site of acute myocardial infarction.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biopsy; Cord Blood Stem Cell Transplantation; Disease Models, Animal; Energy Metabolism; Humans; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Paracrine Communication; Swine; Ventricular Function, Left | 2011 |
Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Bleeding Time; Blood Platelets; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Genotype; Glutathione; Glutathione Peroxidase; Infarction, Middle Cerebral Artery; Mice; Mice, Knockout; P-Selectin; Platelet Aggregation; Reactive Oxygen Species; Risk Factors; Thrombosis | 2011 |
Effect of captopril on serum lipid levels and cardiac mitochondrial oxygen consumption in experimentally-induced hypercholesterolemia in rabbits.
Topics: Adenosine Diphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Captopril; Cell Respiration; Disease Models, Animal; Hypercholesterolemia; Lipids; Male; Mitochondria, Heart; Oxygen; Oxygen Consumption; Rabbits; Spectrophotometry; Time Factors | 2011 |
Placental ischemia impairs middle cerebral artery myogenic responses in the pregnant rat.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Blood Pressure; Brain Edema; Disease Models, Animal; Endothelium, Vascular; Female; Ischemia; Middle Cerebral Artery; Muscle Development; Muscle Tonus; Muscle, Smooth, Vascular; Placenta; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Vasodilation | 2011 |
Defective diacylglycerol-induced Ca2+ entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; C-Reactive Protein; Calcium Channels; Calcium Signaling; Chlorides; Diglycerides; Disease Models, Animal; Ferric Compounds; Gene Expression Regulation; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; ORAI1 Protein; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; RNA, Messenger; Secretory Vesicles; Stromal Interaction Molecule 1; Thrombin; Thrombosis; Time Factors; TRPC Cation Channels; TRPC6 Cation Channel | 2012 |
P2Y1 purinoceptor inhibition reduces extracellular signal-regulated protein kinase 1/2 phosphorylation in spinal cord and dorsal root ganglia: implications for cancer-induced bone pain.
Topics: Adenosine Diphosphate; Animals; Bone Neoplasms; Carcinoma 256, Walker; Cell Line, Tumor; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Immunoblotting; Injections, Spinal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pain; Pain Measurement; Phosphorylation; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord | 2012 |
Protein kinase C isoform ε negatively regulates ADP-induced calcium mobilization and thromboxane generation in platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Disease Models, Animal; Humans; Intracellular Fluid; Mice; Platelet Aggregation; Platelet Count; Protein Kinase C-epsilon; Signal Transduction; Thrombosis; Thromboxanes | 2012 |
Total steroidal alkaloids from Veratrum patulum L. Inhibit platelet aggregation, thrombi formation and decrease bleeding time in rats.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Bleeding Time; Blood Coagulation; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Fibrinolytic Agents; Male; Phytotherapy; Plant Roots; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Rats; Rats, Sprague-Dawley; Rhizome; Thrombin; Thrombosis; Time Factors; Veratrum; Veratrum Alkaloids | 2012 |
Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomarkers; Coronary Circulation; Disease Models, Animal; Endothelium, Vascular; Energy Metabolism; Heart Transplantation; Immunohistochemistry; Male; Metalloporphyrins; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Rats; Rats, Inbred Lew; Time Factors; Tyrosine; Vasodilation; Ventricular Function, Left; Ventricular Pressure | 2012 |
Increased NTPDase activity in lymphocytes during experimental sepsis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Cell Death; Cell Proliferation; Disease Models, Animal; Female; Hydrolysis; Immune System; Leukocytes, Mononuclear; Lymphocytes; Male; Nucleotides; Rats; Rats, Wistar; Sepsis; Tissue Distribution | 2012 |
Hepatic mitochondrial alterations and increased oxidative stress in nutritional diabetes-prone Psammomys obesus model.
Topics: Adenosine Diphosphate; Animals; Diabetes Mellitus; Disease Models, Animal; Electron Transport Complex IV; Electrons; Gerbillinae; Glutathione; Liver; Malondialdehyde; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Oxidative Stress; Oxygen Consumption; Phosphorylation; Rats; Temperature | 2012 |
Effect of cardiopulmonary resuscitation on restoration of myocardial ATP in prolonged ventricular fibrillation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiopulmonary Resuscitation; Disease Models, Animal; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Time Factors; Ventricular Fibrillation | 2013 |
Mechanisms underlying reduced P2Y(1) -receptor-mediated relaxation in superior mesenteric arteries from long-term streptozotocin-induced diabetic rats.
Topics: Adenosine Diphosphate; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Male; Mesenteric Artery, Superior; Nitric Oxide; Nitric Oxide Synthase Type III; Purinergic P2Y Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2Y1; Signal Transduction; Thionucleotides; Time; Vasodilation | 2013 |
Homeostatic adaptations in brain energy metabolism in mouse models of Huntington disease.
Topics: Adenosine Diphosphate; Algorithms; Animals; ATP Synthetase Complexes; Brain Chemistry; Creatine Kinase; Disease Models, Animal; Energy Metabolism; Genotype; Homeostasis; Humans; Huntington Disease; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mice; Neostriatum; Phosphorylation | 2012 |
Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Animals; Antineoplastic Agents; B-Lymphocytes; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Female; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Th1 Cells; Th17 Cells | 2012 |
Mild hyperhomocysteinemia alters extracellular adenine metabolism in rat brain.
Topics: 5'-Nucleotidase; Adenine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Brain; Disease Models, Animal; Extracellular Fluid; Gene Expression Regulation, Enzymologic; GPI-Linked Proteins; Hyperhomocysteinemia; Purines; Rats; Rats, Wistar; RNA, Messenger; Subcellular Fractions; Synaptosomes | 2012 |
A study of the imbalance in B cell-expressed nucleoside triphosphate diphosphohydrolase 1-induced ADP degradation in graft injury during acute antibody-mediated rejection.
Topics: Acute Disease; Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; B-Lymphocytes; Disease Models, Animal; Graft Rejection; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Platelet Activation; RNA, Messenger; Skin Transplantation | 2012 |
Fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage.
Topics: Acute Disease; Adenosine Diphosphate; Animals; Blood Coagulation Tests; Blood Platelets; Disease Models, Animal; Feasibility Studies; Fibrinogen; Hemorrhage; Hemostasis; Hemostatics; Liposomes; Liver Diseases; Male; Microscopy, Immunoelectron; Oligopeptides; Platelet Aggregation; Platelet Count; Rabbits; Thrombocytopenia; Time Factors; Wounds, Penetrating | 2012 |
Hepatic mitochondrial dysfunction in senescence-accelerated mice: correction by long-term, orally administered physiological levels of melatonin.
Topics: Adenosine Diphosphate; Administration, Oral; Aging, Premature; Animals; Antioxidants; Dinitrophenols; Disease Models, Animal; Electron Transport; Female; Free Radical Scavengers; Free Radicals; Male; Melatonin; Mice; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption | 2002 |
Vitamin E attenuates myocardial ischemia-reperfusion injury in murine AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adenosine Diphosphate; Animals; Antioxidants; CD11b Antigen; Disease Models, Animal; Female; Heart Ventricles; Mice; Mice, Inbred C57BL; Models, Cardiovascular; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; P-Selectin; Platelet Aggregation; Reactive Oxygen Species; Risk Factors; Vitamin E | 2002 |
Ultrafine particles affect experimental thrombosis in an in vivo hamster model.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Colloids; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Femoral Vein; Heart Diseases; Injections, Intravenous; Microscopy, Confocal; Microscopy, Electron; Particle Size; Particulate Matter; Platelet Aggregation; Polystyrenes; Silicones; Thrombosis | 2002 |
Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster.
Topics: Adenosine Diphosphate; Animals; Antibodies, Antiphospholipid; Antibodies, Monoclonal; beta 2-Glycoprotein I; Blood Platelets; Carotid Arteries; Cricetinae; Cross Reactions; Disease Models, Animal; Glycoproteins; Humans; Immunoglobulin Fab Fragments; Lupus Coagulation Inhibitor; Phospholipids; Photochemistry; Platelet Aggregation; Protein Binding; Thrombosis | 2003 |
Antithrombotic activity of N,N-dichlorotaurine on mouse model of thrombosis in vivo.
Topics: Adenosine Diphosphate; Amino Acids; Animals; Chloramines; Disease Models, Animal; Fibrinolytic Agents; Kinetics; Male; Mice; Mice, Inbred CBA; Platelet Aggregation; Taurine; Thrombosis; Time Factors | 2002 |
Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in rats.
Topics: Adenosine Diphosphate; Angioplasty, Balloon; Animals; Carotid Stenosis; Cell Division; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Graft Occlusion, Vascular; Hyperplasia; Immunoblotting; Immunohistochemistry; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Physical Conditioning, Animal; Physical Exertion; Platelet Aggregation; Rats; Rats, Wistar; Stents; Swimming; Tunica Intima | 2002 |
Pharmacological studies on internal mammary artery bypass grafts. Action of endogenous and exogenous vasodilators and vasoconstrictors.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Coronary Artery Bypass; Culture Techniques; Disease Models, Animal; Dogs; Endothelium, Vascular; Female; Male; Mammary Arteries; Nitric Oxide; Sensitivity and Specificity; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2002 |
Effects of epinephrine and norepinephrine on hemodynamics, oxidative metabolism, and organ energetics in endotoxemic rats.
Topics: Acidosis, Lactic; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Gas Analysis; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxemia; Energy Metabolism; Epinephrine; Escherichia coli Infections; Glycolysis; Hemodynamics; Humans; Kidney; Lactic Acid; Liver; Myocardium; Nitrates; Norepinephrine; Phosphocreatine; Pyruvates; Rats; Rats, Wistar; Tissue Distribution | 2003 |
Chronic iron administration increases vascular oxidative stress and accelerates arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation; Carotid Arteries; Carotid Artery Thrombosis; Cysteine; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Free Radical Scavengers; Iron; Iron Overload; Iron-Dextran Complex; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Platelet Aggregation; Reactive Oxygen Species; Thromboplastin; Time; Vascular Patency; Vasodilation; Vasodilator Agents | 2003 |
Cellular energetics in hemorrhagic shock: restoring adenosine triphosphate to the cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Antioxidants; Apoptosis; Carotenoids; Disease Models, Animal; Energy Metabolism; Fluid Therapy; Glutamine; Intestine, Small; Liver; Male; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Vitamin A | 2003 |
Diabetes differentially modulated receptor- and non-receptor-mediated relaxation in rat renal artery.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Body Weight; Calcimycin; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar; Renal Artery; Vasodilation; Vasodilator Agents | 2003 |
Inhibition of localized thrombosis in P2Y1-deficient mice and rodents treated with MRS2179, a P2Y1 receptor antagonist.
Topics: Adenosine Diphosphate; Animals; Clopidogrel; Disease Models, Animal; Drug Interactions; Mesenteric Arteries; Mice; Mice, Mutant Strains; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thromboplastin; Thrombosis; Ticlopidine; Vena Cava, Inferior | 2003 |
Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Disease Models, Animal; Humans; Leukocytes; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; P-Selectin; Peptide Fragments; Phosphatidylserines; Plasma; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombin; Thrombosis | 2003 |
Effect of methylimidazole-induced hypothyroidism in a model of low retinal neovascular incidence.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Antithyroid Agents; Disease Models, Animal; Hyperoxia; Hypothyroidism; Incidence; Methimazole; Oxygen; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinal Vessels; Thyroid Gland | 2004 |
Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Catecholamines; Cell Cycle Proteins; Cerebellum; Corpus Striatum; Disease Models, Animal; Disease Progression; DNA-Binding Proteins; Dopamine; Mesencephalon; Mice; Mice, Knockout; NAD; NADP; Protein Serine-Threonine Kinases; Psychomotor Performance; Sex Factors; Tumor Suppressor Proteins | 2004 |
Giant platelet disorder in the Cavalier King Charles Spaniel.
Topics: Adenosine Diphosphate; Animals; Bernard-Soulier Syndrome; Bleeding Time; Blood Platelets; Cytoplasmic Granules; Disease Models, Animal; Dog Diseases; Dogs; Female; Hair Color; Heart Murmurs; Humans; Inbreeding; Male; Mitral Valve Insufficiency; Platelet Aggregation; Platelet Count; Prevalence; Species Specificity; Tricuspid Valve Insufficiency | 2004 |
A zebrafish model for pyruvate dehydrogenase deficiency: rescue of neurological dysfunction and embryonic lethality using a ketogenic diet.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Cloning, Molecular; Diet; Disease Models, Animal; Embryo, Nonmammalian; Fetal Death; Humans; Ketones; Lactates; Molecular Sequence Data; Nervous System; Nervous System Diseases; Pyruvate Dehydrogenase Complex; Pyruvates; Vision Disorders; Zebrafish | 2004 |
Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Blood Pressure; Coronary Circulation; Coronary Vasospasm; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Free Radical Scavengers; Free Radicals; Glutathione; Heart Rate; Models, Cardiovascular; Oxidative Stress; Pericardium; Platelet Aggregation; Swine; Thromboxane B2; Time Factors | 2004 |
Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.
Topics: Adenosine; Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Biomarkers; Brain; Convulsants; Disease Models, Animal; Female; Guanosine; Guanosine Diphosphate; Hydrolysis; Inosine; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Pentylenetetrazole; Phosphopyruvate Hydratase; Purines; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Seizures; Time Factors; Up-Regulation | 2004 |
NHE-1 inhibition improves impaired mitochondrial permeability transition and respiratory function during postinfarction remodelling in the rat.
Topics: Adenosine Diphosphate; Animals; Body Weight; Calcium; Cell Respiration; Citrate (si)-Synthase; Disease Models, Animal; Guanidines; Infarction; Intracellular Membranes; Male; Mitochondria, Heart; Myocardium; Organ Size; Permeability; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones | 2005 |
5'-nucleotidase activity is altered by hypo- and hyperthyroidism in platelets from adult rats.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Platelets; Disease Models, Animal; Hyperthyroidism; Hypothyroidism; Male; Rats; Rats, Wistar; Thyroxine | 2005 |
Platelet P-selectin plays an important role in arterial thrombogenesis by forming large stable platelet-leukocyte aggregates.
Topics: Adenosine Diphosphate; Animals; Arteries; Cell Aggregation; Coronary Disease; Disease Models, Animal; Flow Cytometry; In Vitro Techniques; Leukocytes; Mice; Mice, Inbred C57BL; P-Selectin; Platelet Aggregation; Thrombosis | 2005 |
Chronic heavy ethanol consumption is associated with decreased platelet aggregation in rats.
Topics: Adenosine Diphosphate; Alcoholism; Animal Feed; Animals; Collagen; Disease Models, Animal; Ethanol; Male; Platelet Aggregation; Rats; Rats, Wistar | 2005 |
Hepatic apoptosis after hemorrhagic shock in rats can be reduced through modifications of conventional Ringer's solution.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apoptosis; Apoptosis Regulatory Proteins; Disease Models, Animal; Isotonic Solutions; Liver; Male; Rats; Rats, Sprague-Dawley; Resuscitation; Ringer's Solution; Shock, Hemorrhagic; Stereoisomerism | 2006 |
Biological properties of a specific Galpha q/11 inhibitor, YM-254890, on platelet functions and thrombus formation under high-shear stress.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Cell Shape; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Femoral Artery; Fibrinogen; Fibrinolytic Agents; GTP-Binding Protein alpha Subunits, Gq-G11; Ligation; Macaca fascicularis; P-Selectin; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Regional Blood Flow; Stress, Mechanical; Thrombosis | 2006 |
The metabolism of C-glucose by neurons and astrocytes in brain subregions following focal cerebral ischemia in rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Brain; Brain Infarction; Brain Ischemia; Carbon Radioisotopes; Cell Communication; Cell Death; Disease Models, Animal; Down-Regulation; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Infarction, Middle Cerebral Artery; Male; Neurons; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2006 |
Reconstitution of CD39 in liposomes amplifies nucleoside triphosphate diphosphohydrolase activity and restores thromboregulatory properties.
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Apyrase; Biopsy, Needle; Blotting, Western; Disease Models, Animal; Humans; Immunohistochemistry; Injections, Intravenous; Liposomes; Mice; Mice, Inbred Strains; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Pulmonary Embolism; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Thromboplastin; Time Factors | 2006 |
E22K mutation of RLC that causes familial hypertrophic cardiomyopathy in heterozygous mouse myocardium: effect on cross-bridge kinetics.
Topics: Actins; Adenosine Diphosphate; Animals; Anisotropy; Binding Sites; Cardiomyopathy, Hypertrophic, Familial; Disease Models, Animal; Heterozygote; Humans; Hypertrophy, Left Ventricular; Kinetics; Mice; Mice, Transgenic; Microscopy, Confocal; Muscle Fibers, Skeletal; Mutation; Myocardium; Myocytes, Cardiac; Myosin Light Chains | 2006 |
Adenosine A1 and A2 receptor agonists reduce endotoxin-induced cellular energy depletion and oedema formation in the lung.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Endotoxemia; Endotoxins; Energy Metabolism; Female; Lipopolysaccharides; Lung; Pulmonary Artery; Pulmonary Edema; Rabbits; Receptors, Purinergic P1; Respiratory Distress Syndrome; Time Factors; Uric Acid; Vasoconstriction | 2007 |
Ouabain protects rat hearts against ischemia-reperfusion injury via pathway involving src kinase, mitoKATP, and ROS.
Topics: Adenosine Diphosphate; Animals; Cardiotonic Agents; Creatine; Disease Models, Animal; Heart Rate; Male; Mitochondria, Heart; Mitochondrial Membranes; Myocardial Reperfusion Injury; Ouabain; Oxygen Consumption; Permeability; Potassium Channels; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; src-Family Kinases | 2007 |
Rheolytic pharmacomechanical thrombectomy in experimental chronic deep vein thrombosis: effect of L-arginine on thrombogenicity and endothelial vasomotor function.
Topics: Adenosine Diphosphate; Angiography; Animals; Arginine; Bradykinin; Calcimycin; Disease Models, Animal; Endosonography; Endothelium, Vascular; Microscopy, Electron, Scanning; Nitroprusside; Serotonin; Swine; Thrombectomy; Venous Thrombosis | 2007 |
Genetic strain differences in platelet aggregation and thrombus formation of laboratory rats.
Topics: Adenosine Diphosphate; Animals; Arteriovenous Shunt, Surgical; Bleeding Time; Blood Platelets; Chlorides; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Genetic Variation; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Thrombin; Species Specificity; Thrombosis | 2007 |
The thrombolytic effect of aspirin in animal model.
Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Disease Models, Animal; Female; Fibrinolysis; Humans; Male; Middle Aged; Platelet-Rich Plasma; Thrombolytic Therapy; Thrombosis | 2007 |
A1 adenosine receptor upregulation accompanies decreasing myocardial adenosine levels in mice with left ventricular dysfunction.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Female; Heart Failure; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Myocardium; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation; Ventricular Dysfunction, Left | 2007 |
Platelet aggregometry and receptor binding to predict the magnitude of antithrombotic and bleeding time effects of clopidogrel in rabbits.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Aspirin; Biomarkers; Bleeding Time; Blood Platelets; Carotid Artery Thrombosis; Carotid Artery, Common; Clopidogrel; Disease Models, Animal; Dose-Response Relationship, Drug; Hemostasis; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Protein Binding; Rabbits; Receptors, Purinergic P2; Regional Blood Flow; Thromboxane B2; Ticlopidine | 2007 |
Impaired resting muscle energetics studied by (31)P-NMR in diet-induced obese rats.
Topics: Adaptation, Physiological; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dietary Fats; Dietary Sucrose; Disease Models, Animal; Energy Metabolism; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Male; Mitochondria, Muscle; Muscle, Skeletal; Obesity; Phosphocreatine; Phosphorus Isotopes; Rats; Rats, Wistar | 2008 |
Real-time measurement of non-lethal platelet thromboembolic responses in the anaesthetized mouse.
Topics: Adenosine Diphosphate; Anesthesia; Animals; Aspirin; Blood Platelets; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Erythrocytes; Hemodynamics; Indium Radioisotopes; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Organometallic Compounds; Oxyquinoline; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Transfusion; Pulmonary Embolism; Reproducibility of Results; Thrombin; Thromboembolism; Time Factors | 2008 |
Thrombocytopenia and platelet abnormalities in high-density lipoprotein receptor-deficient mice.
Topics: Adenosine Diphosphate; Animals; Atherosclerosis; Blood Platelets; Cell Aggregation; Cholesterol; Disease Models, Animal; Female; Lipoproteins, HDL; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Lipoprotein; Scavenger Receptors, Class B; Thrombocytopenia | 2008 |
Sepsis induces brain mitochondrial dysfunction.
Topics: Adenosine Diphosphate; Animals; Brain; Disease Models, Animal; Electron Transport; Electron Transport Complex IV; Energy Metabolism; Hydrogen Peroxide; Male; Mice; Mitochondria; Mitochondrial Diseases; Mitochondrial Membranes; Oxidative Phosphorylation; Oxygen Consumption; Sepsis | 2008 |
A standardized 'in vivo' model for the study of experimental arterial thrombosis: description of a method.
Topics: Adenosine Diphosphate; Animals; Computers; Disease Models, Animal; Electric Injuries; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Rats; Rats, Inbred Strains; Thrombosis | 1984 |
Metabolic studies of postischemic acute renal failure in the rat.
Topics: Acute Kidney Injury; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Ischemia; Kidney; Lactates; Lactic Acid; Male; Phosphates; Rats; Rats, Inbred Strains; Time Factors | 1984 |
The interactions of lipids, platelets and endothelial cells in thrombogenesis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Blood Vessels; Coronary Disease; Diet; Disease Models, Animal; Endothelium; Fatty Acids; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Thrombosis; Thromboxane A2 | 1980 |
The mouse pale ear pigment mutant as a possible animal model for human platelet storage pool deficiency.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelet Disorders; Cytoplasmic Granules; Disease Models, Animal; Ear; Female; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mutation; Platelet Count; Serotonin | 1981 |
Human urinary trypsin inhibitor, urinastatin, prevents pancreatic injuries induced by pancreaticobiliary duct obstruction with cerulein stimulation and systemic hypotension in the rat.
Topics: Acute Disease; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amylases; Animals; Cathepsin B; Ceruletide; Cholestasis; Disease Models, Animal; Drug Evaluation, Preclinical; Glycoproteins; Hypotension; Infusions, Intravenous; Malate Dehydrogenase; Male; Pancreatitis; Rats; Rats, Wistar; Trypsin; Trypsin Inhibitors | 1993 |
Inositol trisphosphate, polyphosphoinositide turnover, and high-energy metabolites in focal cerebral ischemia and reperfusion.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Calcium; Carotid Artery, Common; Cerebral Arteries; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Homeostasis; Hydrolysis; Inositol 1,4,5-Trisphosphate; Ischemic Attack, Transient; Neurons; Phosphatidylinositol Phosphates; Rats; Reperfusion; Signal Transduction; Tritium | 1995 |
A study of hepatic mitochondrial respiration and microsomal cytochrome P450 content in mice infected with the liver fluke Fasciola hepatica.
Topics: Adenosine Diphosphate; Animals; Cytochrome P-450 Enzyme System; Disease Models, Animal; Fascioliasis; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Mice, Nude; Microsomes, Liver; Mitochondria, Liver; Oxygen Consumption; Phosphorylation; Species Specificity | 1995 |
Administration of colony stimulating factor-1 to toothless osteopetrotic rats normalizes osteoblast, but not osteoclast, gene expression.
Topics: Adenosine Diphosphate; Alkaline Phosphatase; Animals; Blotting, Northern; Bone and Bones; Carbonic Anhydrases; Collagen; Disease Models, Animal; Gene Expression Regulation; Histones; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Osteoblasts; Osteocalcin; Osteoclasts; Osteopetrosis; Osteopontin; Radiography; Rats; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Sialoglycoproteins; Tibia | 1995 |
Antiischaemic effect of defibrotide treatment in rat kidney.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Fibrinolytic Agents; Ischemia; Kidney; Male; Polydeoxyribonucleotides; Rats; Rats, Wistar; Reperfusion Injury | 1993 |
Prevention of experimental carotid artery thrombosis by applaggin.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Carotid Artery Thrombosis; Crotalid Venoms; Disease Models, Animal; Dogs; Kinetics; Male; Platelet Activation; Platelet Aggregation Inhibitors | 1993 |
Impairment of cardiac function and energetics in experimental renal failure.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Creatinine; Disease Models, Animal; Heart; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Failure, Chronic; Magnetic Resonance Spectroscopy; Male; Multivariate Analysis; Myocardium; Nephrectomy; Phosphates; Phosphocreatine; Rats; Rats, Wistar; Reference Values; Urea | 1993 |
Effect of standard-dose versus high-dose epinephrine on myocardial high-energy phosphates during ventricular fibrillation and closed-chest CPR.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biopsy; Blood Gas Analysis; Cardiopulmonary Resuscitation; Chromatography, High Pressure Liquid; Clinical Protocols; Disease Models, Animal; Drug Evaluation, Preclinical; Epinephrine; Guanosine Triphosphate; Heart Arrest; Hemodynamics; Injections, Intravenous; Inosine; Inosine Monophosphate; Myocardium; Phosphocreatine; Swine; Ventricular Fibrillation | 1993 |
Alterations in energy metabolism of hypertrophied rat cardiomyocytes: influence of propionyl-L-carnitine.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Cardiotonic Agents; Carnitine; Cell Size; Disease Models, Animal; Energy Metabolism; Fatty Acids; Glucose; Heart; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Oxidation-Reduction; Palmitates; Phosphocreatine; Rats; Rats, Inbred WKY | 1995 |
[The changes of blood gas analysis values and platelet aggregability on acute phase in the experimental model of pulmonary embolism prepared by sephadex G-75 (SG-75) injection].
Topics: Acute-Phase Reaction; Adenosine Diphosphate; Animals; Blood Gas Analysis; Carbon Dioxide; Dextrans; Disease Models, Animal; Male; Oxygen; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Pulmonary Embolism; Rabbits | 1996 |
Regional deficits of myocardial blood flow and function in left ventricular pacing-induced heart failure.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Disease Models, Animal; Heart Failure; Myocardial Ischemia; Pacemaker, Artificial; Stress, Physiological; Swine; Systole; Ventricular Function, Left | 1996 |
Chronic endotoxemia and endothelium-dependent vasodilation in coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Body Temperature; Body Weight; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Hemodynamics; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; omega-N-Methylarginine; Rabbits; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1996 |
Skeletal muscle metabolism in experimental heart failure.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Disease Models, Animal; Female; Heart Failure; Monocrotaline; Muscle, Skeletal; NAD; Organ Size; Oxidation-Reduction; Phosphocreatine; Rats; Rats, Sprague-Dawley | 1996 |
YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits platelet-rich thrombosis in mice.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation; Blood Platelets; Disease Models, Animal; Enzyme Activation; Fibrinolytic Agents; Fluorescein; Fluoresceins; Guanylate Cyclase; Indazoles; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Embolism; Serum Globulins; Solubility; Thrombosis | 1997 |
In vitro and in vivo effects of selenium and selenium with vitamin E on platelet functions in diabetic rats relationship to platelet sorbitol and fatty acid distribution.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Synergism; Fatty Acids; Food, Fortified; Linear Models; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Selenium; Selenomethionine; Sorbitol; Thrombin; Vitamin E | 1996 |
Nonpeptide glycoprotein IIb/IIIa inhibitors. 15. Antithrombotic efficacy of L-738,167, a long-acting GPIIb/IIIa antagonist, correlates with inhibition of adenosine diphosphate-induced platelet aggregation but not with bleeding time prolongation.
Topics: Adenosine Diphosphate; Animals; Azepines; Bleeding Time; Disease Models, Animal; Dogs; Drug Administration Routes; Fibrinolytic Agents; Macaca mulatta; Pan troglodytes; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Sulfonamides; Thrombosis | 1997 |
Pneumocystis carinii infection alters GTP-binding proteins in the lung.
Topics: Adenosine Diphosphate; Animals; Blotting, Western; Disease Models, Animal; DNA, Fungal; Ferrets; Fluorescent Antibody Technique, Indirect; GTP-Binding Proteins; Immune Sera; Immunosuppression Therapy; Lung; Male; Molecular Weight; Pneumocystis; Pneumonia, Pneumocystis; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley | 1997 |
The in vitro and in vivo pharmacological profiles of a platelet glycoprotein IIb/IIIa antagonist, NSL-9403.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Femoral Artery; Fibrinogen; Humans; Male; Mice; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pulmonary Embolism; Thrombosis | 1997 |
Changes in adenine nucleotides and lipid hydroperoxides during normothermic cardiopulmonary bypass in a porcine model of type II non-heart-beating donor.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiopulmonary Bypass; Disease Models, Animal; Glutathione; Heart Arrest; Lipid Peroxides; Liver; Resuscitation; Swine; Tissue Donors | 1997 |
A point mutation in the neu-1 locus causes the neuraminidase defect in the SM/J mouse.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; COS Cells; Disease Models, Animal; DNA Mutational Analysis; DNA, Complementary; Dwarfism; Fibroblasts; Genes; Genotype; Glycosylation; Immunologic Deficiency Syndromes; Lysosomal Storage Diseases; Lysosomes; Macromolecular Substances; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Mutant Strains; Molecular Sequence Data; Neuraminidase; Phenotype; Point Mutation; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transfection | 1998 |
Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Blood Platelets; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Targeting; Mice; Mice, Mutant Strains; Platelet Aggregation; Second Messenger Systems; Thromboembolism | 1998 |
Fibrinogen as a factor of thrombosis: experimental study.
Topics: Adenosine Diphosphate; Animals; Disease Models, Animal; Fibrinogen; Humans; In Vitro Techniques; Male; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Rats; Rats, Wistar; Risk Factors; Thromboembolism; Thrombophlebitis; Thrombosis | 1998 |
Energy generation in hypertrophied postischemic myocardium. Feasibility of prolonged inotropic stimulation with dopamine in hypertrophied reperfused left ventricles.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Dopamine; Energy Metabolism; Feasibility Studies; Hypertension; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Wistar; Stimulation, Chemical | 1998 |
Altered mitochondrial function in canine ceroid-lipofuscinosis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Dogs; Glutamic Acid; Malates; Microscopy, Electron; Mitochondria, Liver; Neuronal Ceroid-Lipofuscinoses; Oxygen Consumption; Succinic Acid | 1998 |
Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alzheimer Disease; Animals; Avoidance Learning; Behavior, Animal; Blood Glucose; Brain; Disease Models, Animal; Energy Metabolism; Habituation, Psychophysiologic; Male; Memory; Practice, Psychological; Rats; Rats, Wistar; Receptor, Insulin; Statistics, Nonparametric; Streptozocin | 1998 |
Morphologic and hematologic characteristics of storage pool deficiency in beige rats (Chédiak-Higashi syndrome of rats).
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Chediak-Higashi Syndrome; Collagen; Cytoplasmic Granules; Disease Models, Animal; Female; Hair Color; Male; Platelet Aggregation; Platelet Count; Platelet Storage Pool Deficiency; Rats; Rats, Mutant Strains; Rats, Wistar; Serotonin | 1998 |
31P and 1H NMR spectroscopic studies of liver extracts of carbon tetrachloride-treated rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Hypoxia; Disease Models, Animal; Liver; Liver Cirrhosis, Experimental; Male; Nuclear Magnetic Resonance, Biomolecular; Phosphorus; Protons; Rats; Rats, Wistar; Tissue Extracts | 1999 |
Effect of aluminium-induced Alzheimer like condition on oxidative energy metabolism in rat liver, brain and heart mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Aging; Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Animals; Body Temperature; Brain; Chlorides; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Male; Membrane Fluidity; Mitochondria, Heart; Mitochondria, Liver; Oxidative Phosphorylation; Rats | 1999 |
Platelet aggregation during abdominal surgery in an experimental pig model: the effects of presurgical antibiotic protocols and volume replacement with hydroxyethyl starch.
Topics: Abdomen; Adenosine Diphosphate; Animals; Antibiotic Prophylaxis; Blood Pressure; Blood Volume; Disease Models, Animal; Heart Rate; Hemodilution; Hydroxyethyl Starch Derivatives; Isotonic Solutions; Laparoscopy; Platelet Aggregation; Platelet Count; Swine | 2000 |
Permanent cerebral hypoperfusion: 'preconditioning-like' effects on rat energy metabolism towards acute systemic hypotension.
Topics: Acute Disease; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Energy Metabolism; Hypotension; Ischemic Preconditioning; Male; Rats; Rats, Wistar; Reperfusion Injury | 2000 |
Antiplatelet and antithrombotic effects of orbofiban, a new orally active GPIIb/IIIa antagonist, in guinea pigs.
Topics: Adenosine Diphosphate; Administration, Oral; Alanine; Animals; Arteriovenous Shunt, Surgical; Aspirin; beta-Alanine; Bleeding Time; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Guinea Pigs; Hemostasis; Hypercholesterolemia; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Thrombosis; Urea | 2000 |
The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arteriovenous Shunt, Surgical; Binding, Competitive; Bleeding Time; Blood Platelets; Clopidogrel; Collagen; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Male; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thionucleotides; Thiophenes; Thrombin; Thrombosis; Ticlopidine; Time Factors; Tritium | 2000 |
Comparative study of antithrombotic effect of a low molecular weight heparin and unfractionated heparin in an ex vivo model of deep arterial injury.
Topics: Adenosine Diphosphate; Animals; Arteries; Blood Coagulation Tests; Blood Flow Velocity; Collagen; Disease Models, Animal; Fibrin; Fibrinogen; Fibrinolytic Agents; Hematologic Tests; Heparin; Heparin, Low-Molecular-Weight; Perfusion; Platelet Aggregation; Platelet Function Tests; Swine; Thrombosis | 2000 |
The effects of polysulfonate derivative (GL 2021) on coagulation in vitro and thrombosis in vivo.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Anticoagulants; Arterioles; Blood Coagulation; Collagen; Disease Models, Animal; Fibrinolytic Agents; Humans; Injections, Intravenous; Lasers; Male; Mesenteric Arteries; Partial Thromboplastin Time; Platelet Adhesiveness; Platelet Aggregation; Platelet Count; Polymers; Prothrombin Time; Rats; Rats, Wistar; Sulfonic Acids; Thrombin Time; Thrombosis | 2000 |
Effect of aspirin on platelet desaggregation induced by SR121566, a potent GP-IIb/IIIa antagonist.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Benzylamines; Blood Flow Velocity; Blood Platelets; Carotid Arteries; Disease Models, Animal; Electric Stimulation; Female; Fibrinolytic Agents; Humans; Male; Oligopeptides; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Recombinant Proteins; Thiazoles; Thrombosis; Thrombospondins; Tissue Plasminogen Activator | 2000 |
Effects of acetyl salicylic acid therapy on an experimental thrombosis induced by laser beam.
Topics: Adenosine Diphosphate; Animals; Aspirin; Bleeding Time; Disease Models, Animal; Fibrinogen; Lasers; Male; Partial Thromboplastin Time; Platelet Aggregation; Rats; Rats, Wistar; Thrombosis | 2000 |
Prevention of arterial thrombosis by intravenously administered platelet P2T receptor antagonist AR-C69931MX in a canine model.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Arterial Occlusive Diseases; Bleeding Time; Blood Flow Velocity; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Disease Models, Animal; Dogs; Female; Hemodynamics; Injections, Intravenous; Male; Membrane Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Tunica Intima | 2000 |
Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.
Topics: Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Adenosine Diphosphate; Animals; Blood Platelets; Chromosome Mapping; Disease Models, Animal; Eye; Genes; Genes, Recessive; Genetic Heterogeneity; Hair Color; Hermanski-Pudlak Syndrome; Humans; Kidney; Lipofuscin; Liver; Lysosomes; Melanosomes; Membrane Proteins; Mice; Mice, Inbred C3H; Mice, Mutant Strains; Models, Animal; Monomeric Clathrin Assembly Proteins; Phenotype; Puerto Rico; Serotonin; Skin; Species Specificity | 2000 |
Key role of the P2Y(1) receptor in tissue factor-induced thrombin-dependent acute thromboembolism: studies in P2Y(1)-knockout mice and mice treated with a P2Y(1) antagonist.
Topics: Acute Disease; Adenosine Diphosphate; Animals; Antithrombin III; Disease Models, Animal; Fibrinolytic Agents; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Hydrolases; Platelet Count; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thrombin; Thromboembolism; Thromboplastin | 2001 |
Blood purine and energy status in rats with colitis.
Topics: Acetic Acid; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomarkers; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Energy Metabolism; Hemoglobins; Inosine; Male; Peroxidase; Purines; Rats; Rats, Wistar; Time Factors; Uric Acid | 2001 |
Synthesis and pharmacological evaluation of 2,5-cycloamino-5H-[1]benzopyrano[4,3-d]pyrimidines endowed with in vitro antiplatelet activity.
Topics: Adenosine Diphosphate; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Benzopyrans; Collagen; Disease Models, Animal; Edema; Guinea Pigs; Pain; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrimidines; Rats | 2001 |
Mitochondrial ATPase and high-energy phosphates in failing hearts.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Body Weight; Cardiac Pacing, Artificial; Coronary Circulation; Disease Models, Animal; Dobutamine; Dopamine; Heart Failure; Hemodynamics; Infusions, Intravenous; Magnetic Resonance Spectroscopy; Mitochondria, Heart; Myocardial Infarction; Organ Size; Phosphocreatine; Protein Subunits; Proton-Translocating ATPases; Swine; Ventricular Remodeling | 2001 |
Selective changes in mitochondria respiratory properties in oxidative or glycolytic muscle fibers isolated from G93AhumanSOD1 transgenic mice.
Topics: Adenosine Diphosphate; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Brain; Cell Respiration; Diaphragm; Disease Models, Animal; Disease Progression; Enzyme Activation; Glycolysis; Humans; Mice; Mice, Transgenic; Mitochondria, Muscle; Muscle, Skeletal; Organ Specificity; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1 | 2001 |
Effects of adenosine on thrombosis and thrombolysis in a canine experimental preparation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Flow Velocity; Carotid Arteries; Carotid Artery Thrombosis; Coronary Circulation; Coronary Thrombosis; Disease Models, Animal; Dogs; Electric Injuries; Female; Fibrinolytic Agents; Male; Platelet Aggregation; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator | 2001 |
Organ preservation during experimental liver transplantation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Glutathione; Glutathione Disulfide; Liver Transplantation; Organ Preservation; Purines; Swine | 2000 |
The regulation of platelet-dense granules by Rab27a in the ashen mouse, a model of Hermansky-Pudlak and Griscelli syndromes, is granule-specific and dependent on genetic background.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelets; Cytoplasmic Granules; Disease Models, Animal; Genetic Predisposition to Disease; Hemorrhage; Hermanski-Pudlak Syndrome; Mice; Mice, Mutant Strains; Platelet Storage Pool Deficiency; rab GTP-Binding Proteins; rab27 GTP-Binding Proteins; Serotonin | 2002 |
Examination of stomach wall Mg2+-Na+-K+-dependent ATPase, ATP, and ADP in pylorus-ligated rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Depression, Chemical; Disease Models, Animal; Female; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Ligation; Magnesium; Male; Ouabain; Potassium; Pylorus; Rats; Sodium; Stomach; Stomach Ulcer | 1976 |
Mechanism of action of Pseudomonas aeruginosa exotoxin A in experimental mouse infections: adenosine diphosphate ribosylation of elongation factor 2.
Topics: Adenosine Diphosphate; Animals; Bacterial Toxins; Burns; Disease Models, Animal; Exotoxins; Female; Liver; Mice; Peptide Elongation Factors; Protein Biosynthesis; Pseudomonas aeruginosa; Pseudomonas Infections; Species Specificity | 1978 |
Platelet hypoaggregability in hypothyroid rats.
Topics: Adenosine Diphosphate; Animals; Blood Platelet Disorders; Blood Platelets; Collagen; Disease Models, Animal; Hypothyroidism; Lipids; Lipopolysaccharides; Male; Platelet Aggregation; Rats | 1978 |
Elevation of rat erythrocyte nucleotide levels following acute renal failure induced by glycerol or mercuric chloride.
Topics: Acute Kidney Injury; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chlorides; Creatinine; Disease Models, Animal; Erythrocytes; Female; Glycerol; Guanosine Diphosphate; Guanosine Triphosphate; Mercury; Nucleotides; Phosphates; Rats; Urea | 1978 |
Splanchnic organ adenine nucleotides and their netabolites in haemorrhagic shock.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Dogs; Duodenum; Liver; Pancreas; Shock, Hemorrhagic | 1977 |
Hepatic metabolic changes following energy deprivation by ammonia in patients and rabbits with jaundice.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonia; Ammonium Chloride; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Cholestasis; Disease Models, Animal; Humans; Liver; Male; Mitochondria, Liver; Ornithine Carbamoyltransferase; Rabbits | 1977 |
Sephadex-induced reduction of coronary flow in the isolated rat heart: a model for ischemic heart disease.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Coronary Disease; Disease Models, Animal; Hypoxanthines; Hypoxia; In Vitro Techniques; Inosine; Male; Microspheres; Myocardial Contraction; Myocardium; Perfusion; Phosphocreatine; Polysaccharides; Rats; Sepharose | 1977 |
A model of graded ischemia in the isolated perfused rat heart.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Glucose; Glycogen; Hemodynamics; In Vitro Techniques; Lactates; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphocreatine; Rats | 1976 |
Metabolic responses to varying restrictions of coronary blood flow in swine.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Energy Metabolism; Fatty Acids; Female; Glucose; Glycogen; Heart; Lactates; Male; Myocardium; Oxygen Consumption; Regional Blood Flow; Swine; Ventricular Fibrillation | 1975 |
Resuscitation of the monkey brain after one hour complete ischemia. III. Indications of metabolic recovery.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosylmethionine Decarboxylase; Animals; Brain; Cerebrovascular Circulation; Disease Models, Animal; Electroencephalography; Energy Metabolism; Female; Glucose; Ischemic Attack, Transient; Lactates; Macaca mulatta; Male; Nerve Tissue Proteins; Ornithine Decarboxylase; Phosphocreatine; Polyribosomes; Pyruvates; Time Factors | 1975 |
Proceedings: In vivo activity of tieclopidine, a new drug with platelet aggregation inhibiting, antisludge and antithrombotic properties.
Topics: Adenosine Diphosphate; Animals; Collagen; Disease Models, Animal; Platelet Aggregation; Rats; Thrombosis | 1975 |
Correlation between coronary venous inosine concentration and myocardial wall thickening during regional ischemia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Membrane; Coronary Disease; Coronary Vessels; Disease Models, Animal; Heart; Inosine; Myocardium; Swine | 1975 |
Effects of coronary perfusion during myocardial hypoxia. Comparison of metabolic and hemodynamic events with global ischemia and hypoxemia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Disease; Disease Models, Animal; Female; Glucose; Glycogen; Heart; Hemodynamics; Hypoxia; Lactates; Male; Myocardial Revascularization; Myocardium; Oxygen Consumption; Phosphocreatine; Swine | 1976 |
Effect of atherosclerosis on responses of the perfused rabbit carotid artery to human platelets.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arteriosclerosis; Blood Platelets; Carotid Arteries; Disease Models, Animal; Humans; Male; Nitroprusside; Perfusion; Rabbits; Serotonin | 1992 |
Effect of diabetes mellitus on responses of the basilar artery in rats to products released by platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Basilar Artery; Blood Platelets; Cerebrovascular Disorders; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Prostaglandin Endoperoxides, Synthetic; Rats; Serotonin; Vasodilation | 1992 |
Vascular occlusion of the retina--an experimental model. II. Platelet aggregates.
Topics: Adenosine Diphosphate; Animals; Disease Models, Animal; Female; Fundus Oculi; Leukocytes; Ophthalmic Artery; Platelet Aggregation; Retinal Artery; Retinal Artery Occlusion; Swine; Thrombin | 1992 |
[Antiplatelet effect of clopidogrel].
Topics: Adenosine Diphosphate; Adolescent; Adult; Animals; Bleeding Time; Clopidogrel; Disease Models, Animal; Dogs; Drug Evaluation; Female; Humans; Intracranial Embolism and Thrombosis; Male; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Rabbits; Rats; Thrombosis; Ticlopidine | 1992 |
Effects of combined thromboxane synthetase inhibition/thromboxane receptor antagonism in two models of sudden cardiac death in the canine: limited role for thromboxane.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; Collagen; Coronary Disease; Death, Sudden; Disease Models, Animal; Dogs; Electric Stimulation; Electrophysiology; Female; Heart Rate; Male; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyridines; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1990 |
Antithrombotic activity of the phosphodiesterase III inhibitor pelrinone in a canine model of coronary artery thrombosis: enhancement of efficacy with concurrent alpha 2-adrenergic antagonism.
Topics: Adenosine Diphosphate; Adrenergic alpha-Antagonists; Animals; Blood Coagulation; Coronary Thrombosis; Dioxanes; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemodynamics; Idazoxan; Male; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrimidines | 1991 |
Effect of encainide, ODE, MODE, and flecainide on ADP/5-HT induced platelet aggregation and in the anesthetized dog coronary artery stenosis-occlusion model of intravascular thrombosis.
Topics: Adenosine Diphosphate; Anilides; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Coronary Thrombosis; Disease Models, Animal; Dogs; Encainide; Flecainide; Heart Rate; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Ventricular Function, Left | 1991 |
Computerized optoelectronic induction and registration of arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Computers; Disease Models, Animal; Electric Stimulation; Endothelium, Vascular; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombosis | 1990 |
Inhibition of platelet aggregation by granulocytes stimulated during experimental trauma.
Topics: Adenosine Diphosphate; Animals; Dialysis; Disease Models, Animal; Granulocytes; Plasma; Platelet Aggregation; Platelet Aggregation Inhibitors; Swine; Wounds and Injuries | 1990 |
Hepatic metabolic alterations in rats treated with low-dose endotoxin and aspirin: an animal model of Reye's syndrome.
Topics: Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspirin; Disease Models, Animal; Drug Interactions; Endotoxins; Energy Metabolism; Humans; Ketone Bodies; Liver; Male; Rats; Rats, Inbred Strains; Reye Syndrome | 1989 |
Platelet storage pool deficiency in pigs.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Platelet Disorders; Blood Platelets; Carbon Radioisotopes; Disease Models, Animal; Factor VIII; Fibrinogen; Infusions, Parenteral; Platelet Aggregation; Platelet Storage Pool Deficiency; Serotonin; Swine | 1986 |
ADP plays a key role in thrombogenesis in rats.
Topics: Adenosine Diphosphate; Animals; Clopidogrel; Cyclooxygenase Inhibitors; Disease Models, Animal; Female; In Vitro Techniques; Ketanserin; Platelet Aggregation; Rats; Rats, Inbred Strains; Serotonin; Thrombosis; Ticlopidine | 1988 |
A study of experimental endocarditis in pigs.
Topics: Adenosine Diphosphate; Animals; Disease Models, Animal; Endocarditis; Epoprostenol; Fibrinolysis; Humans; Platelet Aggregation; Platelet Count; Species Specificity; Swine | 1987 |
Alloxan-induced hyperglycemia in rabbits and the response of platelets to aggregating agents in vitro and to exposed subendothelium in vivo.
Topics: Adenosine Diphosphate; Alloxan; Animals; Arteries; Blood Platelets; Cell Adhesion; Collagen; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothelium; Hyperglycemia; Male; Microscopy, Electron, Scanning; Platelet Aggregation; Rabbits | 1987 |
Myocardial high-energy phosphate levels in cardiomyopathic turkeys.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomyopathy, Dilated; Disease Models, Animal; Myocardium; Phosphocreatine; Turkeys | 1986 |
Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Chromonar; Collagen; Coronary Disease; Coumarins; Disease Models, Animal; Dogs; Epinephrine; Male; Platelet Activating Factor; Platelet Aggregation; Regional Blood Flow; Thromboxane B2 | 1985 |
Correlation of plasma serotonin changes with platelet aggregation in an in vivo dog model of spontaneous occlusive coronary thrombus formation.
Topics: Adenosine Diphosphate; Animals; Arteries; Blood Flow Velocity; Coronary Circulation; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dogs; Electric Stimulation; Female; Male; Microscopy, Electron, Scanning; Platelet Aggregation; Quinazolines; Serotonin | 1986 |
Evidence that the rat is not an appropriate model to study the role of prostaglandins in normal or abnormal platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Blood Pressure; Disease Models, Animal; Epinephrine; Humans; Hypertension; Kinetics; L-Lactate Dehydrogenase; Platelet Aggregation; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Species Specificity; Thrombin | 1986 |
Relation between changes in the acid-base and the energy metabolism of the brain in hepatic coma.
Topics: Acid-Base Equilibrium; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bicarbonates; Brain; Carbon Dioxide; Disease Models, Animal; Hemoglobins; Hepatectomy; Hepatic Encephalopathy; Hydrogen-Ion Concentration; Lactates; Male; NAD; Oxygen; Partial Pressure; Phosphocreatine; Pyruvates; Rats | 1971 |
Effect of pentoxifylline on cerebral edema in cats.
Topics: Adenosine Diphosphate; Animals; Brain Edema; Cats; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Phosphodiesterase Inhibitors; Potassium; Sodium; Vasodilator Agents; Xanthines | 1974 |
Platelet aggregation in the rat--relation to human thrombopathias.
Topics: Adenosine Diphosphate; Animals; Blood Platelet Disorders; Blood Platelets; Citrates; Collagen; Densitometry; Disease Models, Animal; Epinephrine; Heparin; Humans; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Rats; Species Specificity | 1972 |
Role of metabolism in pathogenesis of bacteremia due to Diplococcus pneumoniae in rabbits.
Topics: Acetates; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acids; Animals; Carbohydrate Metabolism; Carbon Isotopes; Disease Models, Animal; Glucose; Glycogen; Lactates; Lipid Metabolism; Liver; Liver Glycogen; Lung; Muscles; Myocardium; Penicillin G; Pneumococcal Infections; Proteins; Pyruvates; Rabbits; Sepsis; Streptococcus pneumoniae | 1973 |
Alterations in platelet aggregation associated with adjuvant arthritis in rats.
Topics: Adenosine Diphosphate; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Collagen; Disease Models, Animal; Female; Fibrinogen; Indomethacin; Mycobacterium; Phenylbutazone; Platelet Adhesiveness; Platelet Aggregation; Rats; Time Factors | 1974 |
Chemical induction of fibrinolysis and inhibition of platelet aggregation (with special respect to effect of nonsteroid antiinflammatory drugs).
Topics: Acetates; Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Arteriosclerosis; Arthritis, Rheumatoid; Blood Coagulation; Collagen; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethyl Biscoumacetate; Fibrinolysis; Humans; In Vitro Techniques; Methods; Phenylbutazone; Platelet Adhesiveness; Pyrazoles; Rats; Thrombophlebitis; Warfarin | 1972 |
Metabolic changes in infarcted and non-infarcted myocardium during the postinfarction period.
Topics: Acid Phosphatase; Adenosine Diphosphate; Adenosine Triphosphate; Anabolic Agents; Animals; Disease Models, Animal; Dogs; Glucuronidase; Heart; Heart Ventricles; Lactates; Myocardial Contraction; Myocardial Infarction; Myocardium; Norepinephrine; Phosphocreatine; Proline; Pyruvates; Time Factors | 1972 |
Effects of ischemia on function and metabolism of the isolated working rat heart.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Heart; Heart Failure; Lactates; Male; Myocardium; Oxygen Consumption; Phosphocreatine; Rats; Regional Blood Flow; Time Factors | 1973 |
Graded hypoxia-oligemia in rat brain. I. Biochemical alterations and their implications.
Topics: Acidosis; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Carbon Dioxide; Cerebrovascular Circulation; Disease Models, Animal; Glucosephosphates; Hypoxia; Hypoxia, Brain; Ischemic Attack, Transient; Keto Acids; Lactates; Ligation; Malates; Nitrogen; Oxygen; Oxygen Consumption; Partial Pressure; Phosphocreatine; Rats | 1973 |
Effect of galactose-ethanol feeding on growth in rats.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Body Weight; Diet; Disease Models, Animal; Ethanol; Galactose; Galactosemias; Growth; Hexosediphosphates; Hexosephosphates; Liver; Rats; Uridine Diphosphate Sugars | 1974 |
Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia.
Topics: Acid-Base Equilibrium; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Carbohydrate Metabolism; Carbon Dioxide; Citrates; Disease Models, Animal; Glucose; Glutamates; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Nucleotidases; Oxidation-Reduction; Partial Pressure; Phosphocreatine; Pyruvates; Rats | 1974 |
Cerebral metabolic state following complete compression ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Blood Pressure; Carbohydrate Metabolism; Carbon Dioxide; Cerebral Cortex; Citric Acid Cycle; Disease Models, Animal; Electroencephalography; Glucose; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Mitochondria; Nucleotidases; Oxygen; Partial Pressure; Phosphocreatine; Pyruvates; Rats; Time Factors | 1974 |
Biochemical changes in non-infarcted heart muscle following myocardial infarction.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biopsy; Carbon Isotopes; Coronary Vessels; Disease Models, Animal; Dogs; Heart Ventricles; Hemodynamics; Hydroxyproline; Lactates; Ligation; Myocardial Infarction; Myocardium; Norepinephrine; Oxygen Consumption; Phosphocreatine; Pyruvates; Time Factors; Water | 1971 |
Opioids modulate post-ischemic progression in a rat model of stroke.
Topics: Amidines; Analgesics, Opioid; Animals; Benzamides; Brain; Brain Ischemia; Cytoprotection; Disease Models, Animal; Disease Progression; Dynorphins; Encephalitis; Immune Tolerance; Interleukin-6; Male; Narcotic Antagonists; Neuroprotective Agents; Peptide Fragments; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Stroke | 2008 |