adenosine diphosphate has been researched along with Diabetes Mellitus, Type 2 in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (9.64) | 18.7374 |
| 1990's | 20 (24.10) | 18.2507 |
| 2000's | 28 (33.73) | 29.6817 |
| 2010's | 21 (25.30) | 24.3611 |
| 2020's | 6 (7.23) | 2.80 |
| Authors | Studies |
|---|---|
| Barr, HM; Camden, J; Fischer, B; Shai, E; Varon, D; Weisman, GA; Yelovitch, S | 1 |
| Saengklub, N; Wichaiyo, S | 1 |
| Alasadi, Y; Asgar, JA; Bliden, KP; Chaudhary, R; Duhan, S; Gill, H; Gurbel, PA; Kundan, P; Sharma, T; Singh, A; Tantry, US | 1 |
| Chongming, W; Lin, D; Ning, M; Ruiqi, W; Weiying, L; Xiaopo, Z; Yanan, Y; Yinfeng, T; Yiying, L; Yong, Z; Zhi, Z | 1 |
| Van Hove, L | 1 |
| Balanova, I; Bezak, B; Böhm, A; Danova, K; Dostalova, K; Jajcay, N; Kollarova, M; Lauko, V; Lazurova, L; Mojto, V; Moravcik, R; Petrikova, K; Slezak, P; Varga, I; Zeman, M | 1 |
| Doroszko, A; Fortuna, P; Gajecki, D; Gawryś, J; Gawryś, K; Leśniewska, J; Majda, F; Mlynarz, P; Szahidewicz-Krupska, E; Wiśniewski, J | 1 |
| Bagge, A; Eliasson, L; Esguerra, JL; Mulder, H; Nagao, M; Ofori, JK; Salunkhe, VA; Vishnu, N; Wollheim, CB | 1 |
| Deng, L; Li, Z; Liang, R; Liao, R; Xu, X; Zhang, B; Zhang, L | 1 |
| Akbaş, F; Bahtiyar, N; Hacioğlu, Y; Karimova, A; Niyazoğlu, M; Onaran, I; Ulutin, T; Yilmaz, E | 1 |
| Gharehbaghian, A; Hamidpour, M; Khadem-Maboudi, AA; Mahmoodian, R; Salimian, M | 1 |
| Beaudoin, MS; Herbst, EA; Holloway, GP; Neufer, PD; Perry, CG; Ritchie, IR; Smith, BK; Smith, JC; Wright, DC | 1 |
| Chen, L; Cui, W; Gu, G; Wang, M | 1 |
| Antoun, G; Dent, R; Harper, ME; McMurray, F; McPherson, R; Patten, DA; Peixoto, AC; Slack, RS; Thrush, AB | 1 |
| Hesselink, MK; Hoeks, J; Kooi, ME; Lenaers, E; Meex, R; Mensink, M; Moonen-Kornips, E; Phielix, E; Schrauwen, P; Schrauwen-Hinderling, VB; Sels, JP | 1 |
| Alexandru, N; García-Estañ, J; Jardín, I; Popov, D; Rosado, JA; Salido, GM; Simionescu, M | 1 |
| Araki, S; Haneda, M; Isshiki, K; Itho, J; Kanno, Y; Kashiwagi, A; Kishi, A; Koya, D; Maegawa, H; Matsuno, H; Sugimoto, T; Uzu, T | 1 |
| Abbate, R; Bolli, P; Fatini, C; Gensini, GF; Giusti, B; Gori, AM; Marcucci, R; Paniccia, R; Sticchi, E | 1 |
| Anderson, CA; Anderson, EJ; Kypson, AP; Lehr, EJ; Neufer, PD; Rodriguez, E | 1 |
| Allister, EM; Gyulkhandanyan, AV; Koshkin, V; Lu, H; Wheeler, MB | 1 |
| Egefjord, L; Petersen, AB; Rungby, J | 1 |
| Ebert, T; Fasshauer, M | 1 |
| Chokesuwattanaskul, W; Jimenez, R; Nugent, KM; Perez-Verdia, A; Simoni, G; Simoni, J; Suarez, JA; Yaqub, Y | 1 |
| Grove, EL; Hvas, AM; Kristensen, SD; Larsen, SB; Mortensen, SB | 1 |
| Huang, M; Huypens, P; Joseph, JW; Pillai, R; Schaefer, S; Sheinin, T; Wettig, SD | 1 |
| Bartegi, A; Jardin, I; Rosado, JA; Salido, GM; Zbidi, H | 1 |
| Barrett, F; Gibson, KR; MacRury, SM; Megson, IL; Sharma, S; Winterburn, TJ | 1 |
| Agha, A; Carmody, D; Foley, DP; Kavanagh, GF; Kenny, D; Mylotte, D; O'Reilly, M; Peace, AJ; Smith, D; Tedesco, AF; Thompson, CJ | 1 |
| Chen, T; Qi, J; Qin, B; Tu, HJ; Wang, DH; Wu, FY; Xu, HF | 1 |
| Bianchi, C; Chu, LM; Clements, RT; Dobrilovic, N; Feng, J; Fingleton, JG; Liu, Y; Sellke, FW; Singh, AK | 1 |
| Kasahara, S; Kato, K; Kozawa, O; Matsushima-Nishiwaki, R; Mizuno, T; Sakakibara, S; Tokuda, H | 1 |
| Cerasi, E; Henquin, JC; Jonas, JC; Kaiser, N; Nesher, R; Pertusa, JA | 1 |
| Dow, CS; Falcioni, G; Gabbianelli, R; Swoboda, B; Vince, FP | 1 |
| Blamire, AM; Buckingham, RE; Clarke, K; Madsen, PL; Manners, D; Neubauer, S; Radda, GK; Scheuermann-Freestone, M; Styles, P | 1 |
| Mayhan, WG; Schwaninger, RM; Sun, H | 1 |
| Aspinwall, CA; Berggren, PO; Brandhorst, H; Bränström, R; Corkey, BE; Eckhard, M; Larsson, O; Ostensson, CG; Tibell, A; Välimäki, S | 1 |
| Adinolfi, E; Baricordi, OR; Chiozzi, P; Di Virgilio, F; Morelli, A; Rizzo, R; Solini, A | 1 |
| Ishisaki, A; Kitajima, Y; Kozawa, O; Matsuno, H; Tokuda, H; Zhou, Y | 1 |
| Feijge, MA; Giesen, PL; Heemskerk, JW; Huijberts, M; van der Meijden, PE; van Raak, LP | 1 |
| Brøns, C; Dyerberg, J; Spohr, C; Vaag, A; Winther, K | 1 |
| Antonopoulou, S; Demopoulos, CA; Fragopoulou, E; Karantonis, HC; Phenekos, C; Rementzis, J | 1 |
| Anderson, RA; Chirkov, YY; Ellis, GR; Evans, LM; Frenneaux, MP; Horowitz, JD; Jackson, SK; Lewis, MJ; Morris, K; Rees, A | 1 |
| Akkerman, JW; Feijge, MA; Ferreira, IA; Gorter, G; Heemskerk, JW; Mocking, AI; van Haeften, TW | 1 |
| Hjemdahl, P; Ostenson, CG; Wallén, NH; Yngen, M | 1 |
| Antonopoulou, S; Fragopoulou, E; Ginis, A; Karantonis, HC; Mitsou, E; Mourelatos, A; Phenekos, C; Rementzis, J; Sitara, M | 1 |
| Bakker, SJ; Ciapaite, J; Diamant, M; Heine, RJ; Krab, K; van Eikenhorst, G; Westerhoff, HV | 1 |
| Boden, G; Rao, AK; Vaidyula, VR | 1 |
| De Feyter, HM; Jonkers, RA; Kuipers, H; Nicolay, K; Praet, SF; Prompers, JJ; van Loon, LJ; van Pul, C | 1 |
| Angiolillo, DJ; Bass, TA; Bernardo, E; Charlton, RK; Costa, MA; Desai, B; Guzman, LA; Shoemaker, SB; Yuan, H; Zenni, MM | 1 |
| Ikeda, T; Ishizawa, M; Ishizuka, T; Kajita, K; Matsubara, K; Matsumoto, M; Morita, H; Sugiyama, C; Uno, Y | 1 |
| Bychkivska, Y; Dror, V; Frey, MH; Jeffrey, KD; Johnson, JD; Kalynyak, TB; Luciani, DS; Nguyen, V; Tee, M | 1 |
| De Feyter, HM; Nicolay, K; Praet, SF; Prompers, JJ; van den Broek, NM; van Loon, LJ | 1 |
| Janka, HU; Mehnert, H; Schramm, W; Standl, E | 1 |
| Ibayashi, H; Umeda, F; Wakasugi, H; Watanabe, J | 1 |
| Colette, C; Crastes de Paulet, A; Gouzes, C; Michel, F; Monnier, L; Rodier, M | 1 |
| Anfossi, G; Burzacca, S; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, EM; Piretto, V; Ponziani, MC; Trovati, M | 1 |
| Bohlen, HG; Lash, JM | 1 |
| Cline, G; Gerard, D; Kahn, CR; Magnusson, I; Rothman, DL; Shulman, GI; Shulman, RG | 1 |
| Knofler, R; Malyszko, J; Takada, A; Takada, Y; Taminato, A; Urano, T; Yoshimi, T | 1 |
| Bailbe, D; Giroix, MH; Leclercq-Meyer, V; Malaisse, WJ; Portha, B; Sener, A | 1 |
| BeltrandelRio, H; Ferber, S; Halban, P; Irminger, JC; Newgard, CB; Schnedl, WJ | 1 |
| Ashcroft, FM; Gray, DW; Leow, K; Shimizu, S; Smith, PA; Williams, BA | 1 |
| Akkerman, JW; Banga, JD; de Graaf, JC; Erkelens, DW; Sixma, JJ; van Breugel, HH; Westerveld, HT | 1 |
| Polonsky, KS; Pugh, W; Tang, J; Zhang, H | 1 |
| Armani, U; Carrubba, M; Leoncini, G; Piana, A; Signorello, MG | 1 |
| Acampora, R; Coppola, L; D'Onofrio, F; Giugliano, D; Marfella, R; Nappo, F; Verrazzo, G; Ziccardi, P | 1 |
| Coppola, L; Giugliano, D; Grassia, A; La Marca, C; Tirelli, A; Verrazzo, G; Ziccardi, P | 1 |
| Anfossi, G; Burzacca, S; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, EM; Ponziani, MC; Trovati, M | 1 |
| Graier, WF; Kostner, GM; Schaeffer, G; Wascher, TC | 1 |
| Ferreira, FM; Palmeira, CM; Santos, MS; Seiça, R | 1 |
| Bakker, SJ; Gans, RO; Heine, RJ; Teerlink, T; ter Maaten, JC; Westerhoff, HV | 1 |
| Hjemdahl, P; Li, N; Ostenson, CG; Wallén, NH; Yngen, M | 1 |
| Chuang, DT; Chuang, JL; Machius, M; Tomchick, DR; Wynn, RM | 1 |
| Bonavita, M; Carleo, R; De Matteo, A; Fuccio, F; Gallo, M; Gatti, A; Gobbo, M; Nocerino, L; Veno, L | 1 |
| Barradas, MA; Dandona, P; Mathur, S; Mikhailidis, DP | 1 |
| Inoguchi, T; Kunisaki, M; Nawata, H; Umeda, F; Watanabe, J | 1 |
| Bertoli, E; De Pirro, R; Faloia, E; Fumelli, P; Mazzanti, L; Rabini, RA | 1 |
| Hayashi, S; Miyauchi, H; Shimizu, I; Watanabe, S | 1 |
| Afeltra, A; Amoroso, A; Caccavo, D; Ferri, GM | 1 |
| Berdanier, CD; Deaver, OE; McCusker, RH; Wander, RC | 1 |
| Hawkins, M; Heptinstall, S; Peacock, I | 1 |
| Boden, G; Capitanio, AM; Hershock, D; Kornecki, E; Lukasiewicz, H; Niewiarowski, S; Rawala, R | 1 |
| Bown, E; Carter, RD; Davis, TM; Jones, DB; Mann, JI; Prescott, RJ | 1 |
3 review(s) available for adenosine diphosphate and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Alterations of sodium-hydrogen exchanger 1 function in response to SGLT2 inhibitors: what is the evidence?
Topics: Adenosine Diphosphate; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Glucose; Glucosides; Humans; Sodium; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Sodium-Hydrogen Exchanger 1 | 2022 |
Zinc, alpha cells and glucagon secretion.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cation Transport Proteins; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Homeostasis; Humans; Potassium Channels; Rats; Zinc | 2010 |
Molecular strategies for the treatment of diabetes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Glucose Transporter Type 2; Humans; Islets of Langerhans; Monosaccharide Transport Proteins | 1994 |
11 trial(s) available for adenosine diphosphate and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Glucose; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glycated Hemoglobin; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Lipids; Magnetic Resonance Spectroscopy; Male; Middle Aged; Muscle, Skeletal; Myocardium; Oxygen; Phosphocreatine; Phosphorus Isotopes; Reference Values; Spectroscopy, Near-Infrared | 2003 |
No effect of taurine on platelet aggregation in men with a predisposition to type 2 diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Aged; Biomarkers; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Susceptibility; Double-Blind Method; Humans; Male; Middle Aged; Platelet Aggregation; Prediabetic State; Taurine | 2005 |
Effect of fast-food Mediterranean-type diet on type 2 diabetics and healthy human subjects' platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Body Weight; Diabetes Mellitus, Type 2; Diet; Diet, Mediterranean; Energy Intake; Food Analysis; Humans; Lipids; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Reference Values; Restaurants | 2006 |
Meal-induced platelet activation in Type 2 diabetes mellitus: effects of treatment with repaglinide and glibenclamide.
Topics: Adenosine Diphosphate; Blood Glucose; C-Reactive Protein; Carbamates; Cross-Over Studies; Diabetes Mellitus, Type 2; Eating; Fasting; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Intercellular Adhesion Molecule-1; Male; Middle Aged; P-Selectin; Piperidines; Platelet Activation; Platelet Function Tests; Postprandial Period; Treatment Outcome; von Willebrand Factor | 2006 |
Effect of traditional Greek Mediterranean meals on platelet aggregation in normal subjects and in patients with type 2 diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Diabetes Mellitus, Type 2; Diet, Mediterranean; Female; Greece; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Thrombin | 2006 |
Platelet and monocyte activation by hyperglycemia and hyperinsulinemia in healthy subjects.
Topics: Adenosine Diphosphate; Adult; Atherosclerosis; Blood Platelets; Blood Proteins; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; Hyperinsulinism; Inflammation; Macrophage Activation; Male; Monocytes; Peptide Fragments; Platelet Aggregation | 2006 |
Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease: results of the Optimizing Antiplatelet Therapy in Diabetes Mellitus (OPTIMUS) study.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine | 2007 |
Effects of insulin therapy upon plasma lipid fatty acids and platelet aggregation in NIDDM with secondary failure to oral antidiabetic agents.
Topics: Adenosine Diphosphate; Administration, Oral; Adult; Aged; Blood Glucose; Body Mass Index; Cholesterol Esters; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Linoleic Acid; Linoleic Acids; Middle Aged; Oleic Acid; Oleic Acids; Phospholipids; Platelet Aggregation; Time Factors; Treatment Failure; Triglycerides | 1995 |
Effects of low-dose EPA-E on glycemic control, lipid profile, lipoprotein(a), platelet aggregation, viscosity, and platelet and vessel wall interaction in NIDDM.
Topics: Adenosine Diphosphate; Analysis of Variance; Blood Glucose; Blood Platelets; Blood Viscosity; Collagen; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Eicosapentaenoic Acid; Endothelium, Vascular; Erythrocyte Deformability; Extracellular Matrix; Female; Humans; In Vitro Techniques; Lipoprotein(a); Male; Middle Aged; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation | 1993 |
The effect of a slow release formulation of bezafibrate on lipids, glucose homeostasis, platelets and fibrinogen in type II diabetics: a pilot study.
Topics: Adenosine Diphosphate; Bezafibrate; Blood Glucose; Blood Platelets; Cholesterol; Collagen; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Fibrinogen; Homeostasis; Humans; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Triglycerides | 1990 |
Platelet behaviour in non-insulin-dependent diabetes--influence of vascular complications, treatment and metabolic control.
Topics: Adenosine Diphosphate; Blood Platelets; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Epinephrine; Female; Glyburide; Humans; In Vitro Techniques; Insulin; Male; Metformin; Middle Aged; Serotonin | 1986 |
69 other study(ies) available for adenosine diphosphate and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist.
Topics: Animals; Blood Glucose; Cell Line, Tumor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Molecular Structure; Purinergic P2Y Receptor Agonists; Rats; Rats, Wistar | 2012 |
Serial assessment of thrombogenicity and hemodynamics in patients with type II diabetes in a clinical research unit: Evidence for circadian variations in clot formation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 2; Humans; Thrombosis | 2022 |
Laurolitsine ameliorates type 2 diabetes by regulating the hepatic LKB1-AMPK pathway and gut microbiota.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Aporphines; Diabetes Mellitus, Type 2; Gastrointestinal Microbiome; Glucose; Hypoglycemic Agents; Lactic Acid; Liver; Mice; Mice, Inbred C57BL | 2022 |
A Cannabinoid Type 2 (CB2) Receptor Agonist Augments NOS-Dependent Responses of Cerebral Arterioles During Type 1 Diabetes.
Topics: Adenosine Diphosphate; Animals; Arterioles; Cannabinoid Receptor Agonists; Cannabinoids; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ethanol; N-Methylaspartate; Nitric Oxide Synthase; Nitroglycerin; Rats; Rats, Sprague-Dawley; Vasodilation | 2022 |
In-vitro antiplatelet effect of melatonin in healthy individuals and patients with type 2 diabetes mellitus.
Topics: Adenosine Diphosphate; Blood Platelets; Diabetes Mellitus, Type 2; Humans; Melatonin; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors | 2023 |
Increased Intraplatelet ADMA Level May Promote Platelet Activation in Diabetes Mellitus.
Topics: Adenosine Diphosphate; Adult; Aged; Arginine; Blood Platelets; Calcium; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Platelet Activation; Platelet Aggregation; Risk Factors | 2020 |
Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line; Cells, Cultured; Cytoplasm; Diabetes Mellitus, Type 2; Gene Expression Regulation; Gene Silencing; Glucose; Glucose Intolerance; Humans; Insulin; Insulin-Secreting Cells; Islets of Langerhans; MicroRNAs; Rats; RNA Interference; RNA, Messenger | 2017 |
Design, synthesis and biological evaluation of nitric oxide releasing derivatives of dapagliflozin as potential anti-diabetic and anti-thrombotic agents.
Topics: Adenosine Diphosphate; Animals; Benzhydryl Compounds; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Design; Glucose Tolerance Test; Glucosides; HEK293 Cells; Humans; Hypoglycemic Agents; Male; Mice; Mice, Inbred ICR; Molecular Structure; Nitric Oxide; Platelet Aggregation; Rabbits; Structure-Activity Relationship; Venous Thrombosis | 2018 |
Increased mitochondrial common deletion in platelets from patients with type 2 diabetes is not associated with abnormal platelet activity or mitochondrial function.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aged; Blood Platelets; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Female; Gene Dosage; Gene Expression; Humans; Male; Middle Aged; Mitochondria; P-Selectin; Platelet Activation; Sequence Deletion | 2018 |
The effect of mild agonist stimulation on the platelet reactivity in patients with type 2 diabetes mellitus.
Topics: Adenosine Diphosphate; Biomarkers; Blood Platelets; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Prognosis | 2019 |
Submaximal ADP-stimulated respiration is impaired in ZDF rats and recovered by resveratrol.
Topics: Adenine Nucleotide Translocator 2; Adenosine Diphosphate; Animals; Cell Respiration; Diabetes Mellitus, Type 2; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Insulin Resistance; Male; Mitochondria; Muscle, Skeletal; Rats; Rats, Zucker; Resveratrol; Stilbenes | 2013 |
Acute fluctuation in blood glucose has no effect on platelet aggregation rate.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests | 2014 |
Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals.
Topics: Adenosine Diphosphate; Adult; Diabetes Mellitus, Type 2; Electron Transport Chain Complex Proteins; Electron Transport Complex I; Electron Transport Complex IV; Fatty Acids; Female; Glycated Hemoglobin; Humans; Mitochondria; Muscle, Skeletal; Obesity; Oxidative Phosphorylation; Rectus Abdominis | 2015 |
Lower intrinsic ADP-stimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male type 2 diabetic patients.
Topics: Adenosine Diphosphate; Carbohydrate Metabolism; Cell Respiration; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Lipid Metabolism; Male; Middle Aged; Mitochondria, Muscle | 2008 |
Effect of homocysteine on calcium mobilization and platelet function in type 2 diabetes mellitus.
Topics: Adenosine Diphosphate; Aged; Blood Platelets; Calcium; Calcium Signaling; Case-Control Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Reactive Oxygen Species; Thapsigargin; Thrombin | 2008 |
Correlation between albuminuria and spontaneous platelet microaggregate formation in type 2 diabetic patients.
Topics: Adenosine Diphosphate; Aged; Albuminuria; Blood Flow Velocity; Blood Platelets; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Stress, Mechanical; Waist-Hip Ratio | 2009 |
Platelet aggregability is modulated by eNOS locus in non-type 2 diabetic patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Alleles; Arachidonic Acid; Cohort Studies; Collagen; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Genotype; Humans; Linear Models; Male; Middle Aged; Nitric Oxide Synthase Type III; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic | 2011 |
Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart.
Topics: Adenosine Diphosphate; Adult; Cell Respiration; Citric Acid Cycle; Diabetes Mellitus, Type 2; Fatty Acids; Female; Glutamic Acid; Glutathione; Heart Atria; Heat-Shock Proteins; Humans; Hydrogen Peroxide; Kinetics; Male; Middle Aged; Mitochondria, Heart; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Transcription Factors; Triglycerides | 2009 |
Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Calcium; Diabetes Mellitus, Type 2; Disease Models, Animal; DNA, Mitochondrial; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Membrane Potentials; Mice; Mice, Inbred Strains; Mice, Transgenic; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Ribosomal | 2010 |
Does pioglitazone directly influence platelet aggregation?
Topics: Adenosine Diphosphate; Adult; Aged; Arachidonic Acid; Collagen; Diabetes Mellitus, Type 2; Epinephrine; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Platelet Aggregation; Thiazolidinediones | 2010 |
Effect of pioglitazone on platelet aggregation in a healthy cohort.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Glucose; Chi-Square Distribution; Collagen; Diabetes Mellitus, Type 2; Epinephrine; Female; Humans; Hypoglycemic Agents; Lipids; Liver Function Tests; Male; Middle Aged; Pioglitazone; Platelet Aggregation; Prospective Studies; Thiazolidinediones | 2010 |
Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Biomarkers; Blood Platelets; Case-Control Studies; Chi-Square Distribution; Collagen; Coronary Artery Disease; Denmark; Diabetes Mellitus, Type 2; Female; Humans; Linear Models; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Registries; Risk Assessment; Risk Factors; Smoking; Thrombopoietin; Thromboxane B2 | 2011 |
Aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor-1{beta} plays a critical role in maintaining glucose-stimulated anaplerosis and insulin release from pancreatic {beta}-cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Line, Tumor; Citric Acid Cycle; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Gas Chromatography-Mass Spectrometry; Gene Expression Profiling; Glucose; Insulin; Insulin-Secreting Cells; Insulinoma; Metabolomics; Oxidation-Reduction; Pancreatic Neoplasms; Pentose Phosphate Pathway; Rats; RNA, Small Interfering | 2011 |
Ca2+ leakage rate from agonist-sensitive intracellular pools is altered in platelets from patients with type 2 diabetes.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Line; Diabetes Mellitus, Type 2; Humans; Intracellular Space; Membrane Proteins; SEC Translocation Channels; Sodium-Calcium Exchanger; Thapsigargin; Thrombin | 2011 |
Therapeutic potential of N-acetylcysteine as an antiplatelet agent in patients with type-2 diabetes.
Topics: Acetylcysteine; Adenosine Diphosphate; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glutathione; Humans; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reactive Oxygen Species; Thrombin; Thrombosis | 2011 |
Platelet reactivity in type 2 diabetes mellitus: a comparative analysis with survivors of myocardial infarction and the role of glycaemic control.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Blood Glucose; Blood Platelets; Collagen; Diabetes Mellitus, Type 2; Epinephrine; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Severity of Illness Index; Survivors | 2012 |
Value of dynamic ³¹P magnetic resonance spectroscopy technique in in vivo assessment of the skeletal muscle mitochondrial function in type 2 diabetes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Diabetes Mellitus, Type 2; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; Phosphates; Phosphocreatine; Phosphorus | 2012 |
Changes in microvascular reactivity after cardiopulmonary bypass in patients with poorly controlled versus controlled diabetes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aged; Arterioles; Cardiopulmonary Bypass; Coronary Artery Bypass; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Disease Susceptibility; Endothelium, Vascular; Enzyme Induction; Female; Gene Expression Regulation; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Male; Microcirculation; Middle Aged; Muscle, Skeletal; Nitroprusside; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Substance P; Tyrosine; Vasoconstriction; Vasodilator Agents | 2012 |
Significant correlation between the acceleration of platelet aggregation and phosphorylation of HSP27 at Ser-78 in diabetic patients.
Topics: Adenosine Diphosphate; Aged; Blood Platelets; Case-Control Studies; CD40 Ligand; Diabetes Mellitus, Type 2; Female; Flavonoids; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Imidazoles; Male; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Molecular Chaperones; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Aggregation; Protein Processing, Post-Translational; Pyridines; Serine | 2012 |
Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Gerbillinae; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Membrane Potentials; Mitochondria; NAD; NADP; Oxidation-Reduction | 2002 |
A new method to evaluate spontaneous platelet aggregation in type 2 diabetes by Cellfacts.
Topics: Adenosine Diphosphate; Antioxidants; Azepines; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Triazoles; Vitamin E | 2003 |
Impaired nitric oxide synthase-dependent dilatation of cerebral arterioles in type II diabetic rats.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arterioles; Blotting, Western; Cerebrovascular Circulation; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Obesity; Rats; Rats, Zucker; Vasodilation; Vasodilator Agents | 2003 |
Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes.
Topics: Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Diabetes Mellitus, Type 2; Diazoxide; Dose-Response Relationship, Drug; Glucose; Humans; Islets of Langerhans; Kinetics; Magnesium Chloride; Membrane Potentials; Membrane Proteins; Oleic Acid; Palmitoyl Coenzyme A; Patch-Clamp Techniques; Potassium Channels | 2004 |
Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Apoptosis; Apyrase; Autocrine Communication; Cell Shape; Cytidine Triphosphate; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fibroblasts; Fibronectins; Gene Expression Regulation; Humans; Interleukin-6; Membrane Potentials; Paracrine Communication; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Uridine Diphosphate; Uridine Triphosphate | 2004 |
P2Y12 receptors play a significant role in the development of platelet microaggregation in patients with diabetes.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aged; Diabetes Mellitus, Type 2; Female; Humans; Male; Membrane Proteins; Middle Aged; Piperazines; Piperidines; Platelet Aggregation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reference Values | 2005 |
Platelet P2Y12 receptors enhance signalling towards procoagulant activity and thrombin generation. A study with healthy subjects and patients at thrombotic risk.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Platelets; Calcium Signaling; Case-Control Studies; Clopidogrel; Diabetes Mellitus, Type 2; Humans; In Vitro Techniques; Membrane Proteins; Middle Aged; Phosphatidylserines; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stroke; Thrombin; Thrombosis; Ticlopidine | 2005 |
Platelet nitrate responsiveness in fasting and postprandial type 2 diabetes.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Platelets; Brachial Artery; Diabetes Mellitus, Type 2; Fasting; Female; Free Radicals; Humans; Lipid Peroxidation; Male; Middle Aged; Nitrates; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Oxidative Stress; Platelet Aggregation; Postprandial Period; Time Factors; Vasodilation | 2005 |
Platelet inhibition by insulin is absent in type 2 diabetes mellitus.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Collagen; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Homeostasis; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Membrane Proteins; Perfusion; Phosphoproteins; Platelet Adhesiveness; Platelet Aggregation; Receptor, Insulin; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction | 2006 |
Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects. Implications for a mechanism linking obesity and type 2 diabetes.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Diabetes Mellitus, Type 2; Hydrogen Peroxide; Male; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Models, Biological; Obesity; Oxidation-Reduction; Palmitoyl Coenzyme A; Rats; Reactive Oxygen Species | 2006 |
31P MR spectroscopy and in vitro markers of oxidative capacity in type 2 diabetes patients.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Biomarkers; Diabetes Mellitus, Type 2; Humans; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Oxidation-Reduction; Oxygen; Oxygen Consumption; Phosphorus Isotopes | 2006 |
Platelet aggregation in obese and diabetic subjects: association with leptin level.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Platelets; Diabetes Mellitus, Type 2; Female; Humans; Leptin; Male; Middle Aged; Obesity; Platelet Aggregation; Thrombin | 2007 |
Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aryl Hydrocarbon Receptor Nuclear Translocator; Calcium; Calcium Signaling; Calpain; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endoplasmic Reticulum; Glucose; Homeostasis; Humans; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Mitochondria; Presenilin-1; Protein Isoforms; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2008 |
Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle mitochondrial dysfunction.
Topics: Adenosine Diphosphate; Blood Glucose; Diabetes Mellitus, Type 2; Glucose Intolerance; Humans; Insulin Resistance; Magnetic Resonance Spectroscopy; Middle Aged; Mitochondrial Diseases; Models, Biological; Muscle, Skeletal; Phosphocreatine; Phosphorus Isotopes; Prediabetic State; Severity of Illness Index | 2008 |
Platelet enzyme activities in diabetes mellitus in relation to endothelial damage.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adenylyl Cyclases; Adolescent; Adult; Aged; beta-Thromboglobulin; Blood Platelets; Cyclic AMP; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Epoprostenol; Humans; Malondialdehyde; Middle Aged; Platelet Aggregation; von Willebrand Factor | 1983 |
Effect of vitamin E on platelet aggregation in diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Platelet Aggregation; Thromboxane B2; Vitamin E | 1984 |
Impaired insulin-induced platelet antiaggregating effect in obesity and in obese NIDDM patients.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Blood Pressure; Case-Control Studies; Cholesterol; Cholesterol, HDL; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glycated Hemoglobin; Humans; In Vitro Techniques; Insulin; Male; Obesity; Platelet Aggregation Inhibitors; Recombinant Proteins; Reference Values; Triglycerides | 1995 |
Endothelial-dependent vasodilation is preserved in non-insulin-dependent Zucker fatty diabetic rats.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Arterioles; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Intestines; Least-Squares Analysis; Male; Nitric Oxide; Nitroprusside; Obesity; omega-N-Methylarginine; Rats; Rats, Zucker; Thinness; Vasodilation | 1995 |
Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Biological Transport; Diabetes Mellitus, Type 2; Female; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glycogen; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Muscles; Organophosphates; Patch-Clamp Techniques; Phosphocreatine; Phosphorylation | 1995 |
Daily variations of platelet aggregation in relation to blood and plasma serotonin in diabetes.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Circadian Rhythm; Collagen; Diabetes Mellitus, Type 2; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Serotonin | 1994 |
Metabolic, ionic, and secretory response to D-glucose in islets from rats with acquired or inherited non-insulin-dependent diabetes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diabetes Mellitus, Type 2; Glucose; Islets of Langerhans; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Rubidium Radioisotopes; Streptozocin | 1993 |
Two types of potassium channel regulated by ATP in pancreatic B cells isolated from a type-2 diabetic human.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Diabetes Mellitus, Type 2; Electric Conductivity; Electrophysiology; Humans; Islets of Langerhans; Kinetics; Male; Potassium Channels; Potassium Chloride; Tetraethylammonium; Tetraethylammonium Compounds; Tolbutamide | 1993 |
Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Blood Glucose; Body Weight; Calcium; Diabetes Mellitus; Diabetes Mellitus, Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Obesity; Perfusion; Potassium Chloride; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Rats, Zucker; Reference Values; Thionucleotides; Time Factors | 1996 |
Hyperactivity and increased hydrogen peroxide formation in platelets of NIDDM patients.
Topics: Adenosine Diphosphate; Aged; beta-Thromboglobulin; Blood Platelets; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniques; Male; Middle Aged; Platelet Activating Factor; Risk Factors; Thrombin; Thrombosis | 1997 |
L-arginine for testing endothelium-dependent vascular functions in health and disease.
Topics: Adenosine Diphosphate; Adult; Age Factors; Arginine; Blood Glucose; Blood Pressure; Blood Viscosity; Cholesterol; Diabetes Mellitus, Type 2; Diastole; Female; Humans; Hypercholesterolemia; Hypertension; Infusions, Intravenous; Male; Middle Aged; omega-N-Methylarginine; Platelet Aggregation; Reference Values; Regression Analysis; Smoking; Stereoisomerism; Systole | 1997 |
Effect of insulin on blood rheology in non-diabetic subjects and in patients with Type 2 diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Aged; Blood Glucose; Blood Viscosity; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Erythrocyte Deformability; Female; Glycated Hemoglobin; Humans; Insulin; Male; Middle Aged; Platelet Aggregation; Rheology | 1997 |
Platelet resistance to nitrates in obesity and obese NIDDM, and normal platelet sensitivity to both insulin and nitrates in lean NIDDM.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Blood Glucose; Blood Platelets; Blood Pressure; Body Mass Index; Cholesterol; Cholesterol, HDL; Cyclic GMP; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Male; Nitroglycerin; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Thinness; Triglycerides | 1998 |
Alterations in platelet Ca2+ signalling in diabetic patients is due to increased formation of superoxide anions and reduced nitric oxide production.
Topics: Adenosine Diphosphate; Adult; Antioxidants; Blood Platelets; Calcium; Calcium Signaling; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Glutathione; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Aggregation; Superoxides; Thapsigargin | 1999 |
Age-related alterations in liver mitochondrial bioenergetics of diabetic Goto-Kakizaki rats.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aging; Analysis of Variance; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Energy Metabolism; Liver; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Mutant Strains; Rats, Wistar | 1999 |
The potential role of adenosine in the pathophysiology of the insulin resistance syndrome.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Coronary Disease; Diabetes Mellitus, Type 2; Erythropoiesis; Fatty Acids; Heart Rate; Hematocrit; Humans; Hyperinsulinism; Hypertrophy; Insulin Resistance; Islets of Langerhans; Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Biological; Natriuresis; Obesity; Oxidative Phosphorylation; Renal Circulation; Risk Factors; Sodium; Superoxides; Sympathetic Nervous System; Uric Acid; Vasodilation | 2001 |
Acute hyperglycemia increases soluble P-selectin in male patients with mild diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Body Mass Index; Diabetes Mellitus, Type 2; Endothelium, Vascular; Flow Cytometry; Glucose Tolerance Test; Humans; Hyperglycemia; Immunoassay; Male; P-Selectin; Solubility; Thrombin; von Willebrand Factor | 2001 |
Structure of rat BCKD kinase: nucleotide-induced domain communication in a mitochondrial protein kinase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Escherichia coli; Histidine Kinase; Humans; Mitochondria; Models, Molecular; Molecular Sequence Data; Protein Kinases; Protein Structure, Secondary; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction | 2001 |
[Evaluation of the effect of picotamide on platelet function in diabetic subjects].
Topics: Adenosine Diphosphate; Aged; Blood Platelets; Collagen; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Phthalic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane-A Synthase | 1990 |
Effects of vitamin E administration on platelet function in diabetes mellitus.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Blood Glucose; Blood Platelets; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Thromboxane B2; Time Factors; Vitamin E | 1990 |
Altered cellular Ca2+ and Na+ transport in diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Calcium; Calcium-Transporting ATPases; Cholesterol; Cytosol; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; In Vitro Techniques; Kinetics; Male; Membrane Fluidity; Membrane Lipids; Middle Aged; Phospholipids; Reference Values; Sodium; Sodium-Potassium-Exchanging ATPase; Thrombin; Triglycerides | 1990 |
Increased platelet aggregation in psoriasis.
Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Collagen; Diabetes Mellitus, Type 2; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Aggregation; Psoriasis | 1985 |
[Evaluation of various parameters of platelet function in subjects with type II diabetes mellitus. Methodologic study of the changes in PF4 and beta-TG].
Topics: Adenosine Diphosphate; Adult; Aged; Beta-Globulins; beta-Thromboglobulin; Blood Platelets; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4 | 1986 |
Diet effects on membrane phospholipid fatty acids and mitochondrial function in BHE rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Aspartic Acid; Coconut Oil; Corn Oil; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Fatty Acids; Glycerophosphates; Malates; Male; Membrane Lipids; Mitochondria, Liver; NAD; Oils; Phospholipids; Plant Oils; Rats; Rats, Mutant Strains | 1986 |
Fibrinogen interaction with platelets of diabetic subjects.
Topics: Adenosine Diphosphate; Adult; Aged; Alprostadil; Antibodies, Monoclonal; Binding Sites; Blood Platelets; Chymotrypsin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Membrane Glycoproteins; Reference Values | 1987 |
Determinants of ADP-induced platelet aggregation in diabetes mellitus.
Topics: Adenosine Diphosphate; Blood Platelets; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fatty Acids; Humans; Phospholipids; Platelet Aggregation; Reference Values | 1986 |