adenosine diphosphate has been researched along with Coronary Artery Disease in 108 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (2.78) | 18.7374 |
| 1990's | 3 (2.78) | 18.2507 |
| 2000's | 45 (41.67) | 29.6817 |
| 2010's | 52 (48.15) | 24.3611 |
| 2020's | 5 (4.63) | 2.80 |
| Authors | Studies |
|---|---|
| Ahrens, I; Bassler, N; Bode, C; Diehl, P; Eisenhardt, SU; Fricke, A; Olivier, CB; Peter, K; Sander, L; Sharma, P; Siegel, PM; Stamm, J; Wang, X; Ying, YL | 1 |
| Abe, JI; Amaya, DN; Banchs, J; Brookes, PS; Burks, JK; Chung, C; Cooke, JP; Deswal, A; Entman, ML; Fujiwara, K; Gi, YJ; Guo, H; Gupte, AA; Hamilton, DJ; Herrmann, J; Imanishi, M; Isgandarova, S; Kleinerman, ES; Ko, KA; Kotla, S; Krishnan, S; Le, NT; Lin, SH; Maggirwar, SB; McBeath, E; Milgrom, SA; Moczygemba, M; Patel, ZS; Schadler, KL; Schifitto, G; Shen, YH; Thomas, TN; Yoon, Y; Yusuf, SW; Zhang, A | 1 |
| Angiolillo, DJ; Been, L; Franchi, F; Galli, M; Rollini, F; Zenni, MM | 1 |
| Han, K; Huang, X; Ma, M; Sun, T; Yang, S; Zhao, Z; Zhou, Y | 1 |
| Che, J; Chen, K; Dou, S; Liu, H; Liu, X; Wang, W; Wang, X; Zhang, X; Zhou, X | 1 |
| Ferenc, M; Hochholzer, W; Löffelhardt, N; Mashayekhi, K; Neumann, FJ; Nührenberg, T; Stratz, C; Trenk, D; Valina, CM | 1 |
| Chen, S; Li, S; Xie, W; Yin, Q; Zhang, M | 1 |
| Brunner, S; Hamm, W; Lackermair, K; Mehr, M; Rizas, K | 1 |
| Lei, H; Liu, Q; Luo, S | 1 |
| Angiolillo, DJ; Bass, TA; Darlington, A; Desai, B; Franchi, F; Guzman, LA; Muñiz-Lozano, A; Patel, R; Rollini, F; Tello-Montoliu, A; Thano, E; Wilson, RE | 1 |
| Alexopoulos, D; Angiolillo, DJ; Aradi, D; Becker, RC; Bhatt, DL; Bonello, L; Curzen, N; Geisler, T; Gurbel, PA; Jeong, YH; Kirtane, A; Mahla, E; Marcucci, R; Price, MJ; Rao, SV; Reny, JL; Sibbing, D; Siller-Matula, J; Stone, GW; Tantry, US; Ten Berg, J; Trenk, D; Waksman, R | 1 |
| Gesheff, MG; Gurbel, PA; Mahla, E; Tantry, US | 1 |
| Gremmel, T; Kopp, CW; Koppensteiner, R; Panzer, S; Steiner, S; Xhelili, E | 1 |
| Asher, E; Beigel, R; Fefer, P; Hod, H; Matetzky, S; Savion, N; Shechter, M; Shenkman, B; Varon, D | 1 |
| Bode, C; Brandt, C; Diehl, P; Moser, M; Olivier, CB; Olschewski, M; Schnabel, K; Weik, P; Zhou, Q | 1 |
| Diodati, JG; Lordkipanidzé, M; Palisaitis, DA; Pharand, C; Schampaert, E | 3 |
| Hunnangkul, S; Kamkaew, R; Likidlilid, A; Poldee, S; Suktitipat, B; Tassaneetrithep, B; Tresukosol, D | 1 |
| Gick, M; Hochholzer, W; Kirtane, AJ; Leggewie, S; Neumann, FJ; Nührenberg, TG; Stone, GW; Stratz, C; Trenk, D; Valina, CM | 1 |
| Gierlotka, M; Kaczmarski, J; Kim, MH; Kuliczkowski, W; Serebruany, V; Sliwka, J; Steter, D; Zembala, M; Zysko, D | 1 |
| Bijak, M; Boryczka, K; Golanski, J; Golanski, R; Kaczmarski, J; Kuliczkowski, W; Watala, C | 1 |
| Dunne, E; Egan, K; Foley, D; Kenny, D; McFadden, S | 1 |
| Barbieri, L; Bellomo, G; De Luca, G; Marino, P; Nardin, M; Pergolini, P; Rolla, R; Schaffer, A; Suryapranata, H; Verdoia, M | 1 |
| Ferreiro, JL; Hernández-Romero, D; Hurtado, J; Jover, E; Marín, F; Orenes-Piñero, E; Quintana, M; Rivera, J; Silvente, A; Tello-Montoliu, A; Valdés, M | 1 |
| Bernlochner, I; Gross, L; Jaitner, J; Kastrati, A; Laugwitz, KL; Mayer, K; Morath, T; Orban, M; Rössner, L; Sibbing, D | 1 |
| Barbieri, L; Bellomo, G; Daffara, V; De Luca, G; Marino, P; Nardin, M; Pergolini, P; Rolla, R; Sartori, C; Schaffer, A; Suryapranata, H; Verdoia, M | 1 |
| Durstberger, M; Eichelberger, B; Gremmel, T; Kopp, CW; Koppensteiner, R; Lee, S; Panzer, S | 1 |
| Holm, M; Rihan Hye, S; Tornvall, P; van der Linden, J; Westerberg, J | 1 |
| Fukushima, K; Iwata, Y; Kitahara, H; Kobayashi, Y; Komuro, I; Kuroda, N; Nakayama, T; Nomura, F; Ooyama, M | 1 |
| Chetty, N; Crowther, NJ; Naran, NH | 1 |
| Berndt, MC; Dicker, P; Foley, DP; Kenny, D; Peace, AJ; Tedesco, AF | 1 |
| Bauersachs, J; Eigenthaler, M; Ertl, G; Flierl, U; Schäfer, A; Störk, S; Walter, U; Weinberger, S | 1 |
| Béres, BJ; Kerecsen, G; Kiss, RG; László, A; Masszi, T; Préda, I; Tóth-Zsámboki, E; Vargová, K | 1 |
| Fu, W; Guo, H; Huang, J; Huang, L; Jian, Z; Li, A; Li, J; Qian, D; Song, Y | 1 |
| Schneider, DJ; Sobel, BE | 1 |
| Akers, WS; Campbell, CL; Charnigo, R; Dunn, SP; Holt, J; Oestreich, JH; Smyth, SS; Steinhubl, SR | 1 |
| Goto, S; Serebruany, V | 1 |
| Braun, S; Hadamitzky, M; Kastrati, A; Morath, T; Schömig, A; Sibbing, D; Stegherr, J; Vogt, W; von Beckerath, N | 1 |
| Ballantyne, CM; Bergeron, AL; Bray, PF; Chen, C; Dong, JF; Johnson, SL; Kimball, KT; Lin, PH; Lumsden, AB; Morrisett, JD; Nambi, V | 1 |
| Bilkova, D; Hajkova, J; Kala, P; Kvasnicka, J; Marinov, I; Motovska, Z; Petr, R; Simek, S; Widimsky, P | 1 |
| Abraham, D; Burg, MM; Chaplin, W; Kuruvilla, S; Shimbo, D; Wasson, LT | 1 |
| Antonino, MJ; Bliden, KP; Conley, PB; Gretler, DD; Gurbel, PA; Jurek, MM; Pakyz, RE; Shuldiner, AR; Stephens, G; Tantry, US | 1 |
| Braun, S; Kastrati, A; Mehilli, J; Morath, T; Schömig, A; Schulz, S; Sibbing, D; Stegherr, J; von Beckerath, N | 1 |
| Bouman, HJ; Breet, NJ; Hackeng, CM; Parlak, E; Taubert, D; ten Berg, JM; ten Cate, H; van Werkum, JW | 1 |
| Fukushima, K; Iwata, Y; Kitahara, H; Kobayashi, Y; Komuro, I; Kuroda, N; Kuwabara, Y; Nomura, F; Ooyama, M | 1 |
| Bolliger, D; Levy, JH; Rumph, B; Szlam, F; Tanaka, KA | 1 |
| Braun, S; Kastrati, A; Mehilli, J; Morath, T; Sarafoff, N; Schömig, A; Schulz, S; Sibbing, D; Stegherr, J; von Beckerath, N | 1 |
| Gao, P; Gao, R; Hu, SS; Li, L; Xiong, H; Zheng, Z | 1 |
| Jakubowski, JA; Li, YG; Luo, J; Payne, CD; Small, DS; Tomlin, ME; Winters, KJ | 1 |
| Abbate, R; Antonucci, E; Balzi, D; Giusti, B; Gori, AM; Maggini, N; Marcucci, R; Miranda, M; Paniccia, R; Prisco, D | 1 |
| Buckland, RJ; Jakubowski, JA; Judge, HM; Patil, SB; Storey, RF | 1 |
| Fukushima, K; Iwata, Y; Kitahara, H; Kobayashi, Y; Komuro, I; Kuroda, N; Nomura, F; Ooyama, M | 1 |
| Jannati, M; Khalili, A; Kojuri, J; Mahboodi, A; Mahmoody, Y; Zangbar Sabegh, B | 1 |
| Angiolillo, DJ; Vivas, D | 1 |
| Nathisuwan, S; Panomvana, D; Sansanayudh, N; Siriswangvat, S | 1 |
| Angiolillo, DJ; Becker, R; Bhatt, DL; Blindt, R; Bonello, L; Cattaneo, M; Collet, JP; Cuisset, T; Gachet, C; Gurbel, PA; Jennings, LK; Kereiakes, D; Marcucci, R; Montalescot, G; Paganelli, F; Price, MJ; Sibbing, D; Tantry, US; Trenk, D; Van Werkum, JW; Waksman, R | 1 |
| Grove, EL; Hvas, AM; Kristensen, SD; Larsen, SB; Mortensen, SB | 1 |
| Hwang, JY; Hwang, SJ; Jeong, YH; Kang, MK; Kim, IS; Koh, JS; Kwak, CH; Park, Y | 1 |
| Jilma, B; Siller-Matula, JM | 1 |
| Abbate, R; Antonucci, E; Gori, AM; Maggini, N; Marcucci, R; Miranda, M; Paniccia, R; Prisco, D; Romano, E | 1 |
| Antonino, MJ; Bliden, KP; Cummings, CC; Dubois, BV; Gesheff, T; Gurbel, PA; Herzog, WR; Tantry, US | 1 |
| Kafian, S; Kalani, M; Mobarrez, F; Samad, BA; Wallén, H | 1 |
| Babin, J; Bonnefoy, A; Bryckaert, M; Labarthe, B; Théroux, P | 1 |
| Jalkanen, S; Kiviniemi, TO; Mercier, N; Miiluniemi, M; Saraste, A; Silvola, J; Yegutkin, GG | 1 |
| Ahn, JH; Bliden, KP; Gho, EH; Gurbel, PA; Hwang, JY; Hwang, SJ; Jeong, YH; Kim, S; Kwak, CH; Kwon, TJ; Park, JR; Park, Y; Tantry, US | 1 |
| Chan, MY; Cornel, JH; Erlinge, D; Goodman, SG; Gurbel, PA; Huber, K; Jakubowski, JA; Ohman, EM; Roe, MT; Shah, S; Tantry, US | 1 |
| Bauersachs, J; Flierl, U; Fraccarollo, D; Lausenmeyer, E; Massberg, S; Rosenstock, T; Schäfer, A; Schulz, C | 1 |
| Bruno, V; Freynhofer, MK; Huber, K; Wojta, J | 1 |
| Demopoulos, CA; Kolovou, G; Kolovou, V; Papakonstantinou, VD; Stamatakis, G; Verouti, SN; Xanthopoulou, MN | 1 |
| Eikelboom, JW; Hirsh, J; Johnston, M; Li, C; Liang, Y; Mehta, S; Pare, G; Sloane, D; Teo, KK; Yi, Q; Zhu, J | 1 |
| Badr Eslam, R; Kaider, A; Lang, IM; Panzer, S | 1 |
| Barinagarrementería-Aldatz, F; Cantú-Brito, C; De la Peña-Díaz, A; González-Pacheco, H; Izaguirre-Avila, R; Quiroz-Martínez, A; Ramírez-Gutierrez, AE; Ruiz-Sandoval, JL | 1 |
| Aggarwal, A; Gennari, FJ; Kabbani, SS; Rimmer, JM; Schneider, DJ; Sobel, BE; Taatjes, DJ | 1 |
| Jacobs, C; Kelm, M; Meila, D; Scharf, RE; Schrör, K; Strauer, BE; Weber, AA; Weber, S; Zotz, RB | 1 |
| Chirkov, YY; Holmes, AS; Horowitz, JD; Stewart, S; Willoughby, SR | 1 |
| Aggarwal, A; Schneider, DJ; Sobel, BE | 1 |
| Allal, J; Brabant, S; Brizard, A; Christiaens, L; Macchi, L; Mauco, G; Sorel, N | 1 |
| Bliden, KP; Gurbel, PA; Hiatt, BL; O'Connor, CM | 1 |
| Beinart, R; Bienart, R; Goldenberg, I; Guetta, V; Hod, H; Matetzky, S; Novikov, I; Pres, H; Savion, N; Shechter, M; Shenkman, B; Varon, D | 1 |
| Baumann, PQ; Schneider, DJ; Sobel, BE; Whitaker, DA | 1 |
| Berti, S; Biagini, A; Clerico, A; Gianetti, J; Maffei, S; Paoli, F; Paradossi, U; Parri, MS; Sbrana, S | 1 |
| Ciftçi, O; Dirican, A; Domaniç, N; Ekmekçi, H; Gürel, C; Işler, I; Kökoğlu, E; Sönmez, H; Ulutin, T | 1 |
| Binkley, PF; Bray, PF; Cooke, GE; Ferketich, AK; Frid, DJ; Goldschmidt-Clermont, PJ; Liu-Stratton, Y; Magorien, RD; Moeschberger, ML | 1 |
| Bauriedel, G; Lüderitz, B; Nickenig, G; Schneider-Schmitt, M; Skowasch, D; Viktor, A | 1 |
| Barnard, MR; Fox, ML; Frelinger, AL; Furman, MI; Li, Y; Linden, MD; Michelson, AD | 1 |
| Kastrati, A; Schömig, A; Sibbing, D; von Beckerath, N; von Beckerath, O | 1 |
| Becker, DM; Becker, LC; Bray, PF; Faraday, N; Herrera-Galeano, JE; Moy, TF; Segal, JB; Yanek, LR | 1 |
| Barnard, MR; Fox, ML; Frelinger, AL; Furman, MI; Lau, WC; Li, Y; Linden, MD; McLaughlin, TJ; Michelson, AD | 1 |
| Eriksson-Berg, M; Håkan Wallén, N; Hjemdahl, P; Landgren, BM; Li, N; Schenck-Gustafsson, K | 1 |
| Angiolillo, DJ; Bass, TA; Bernardo, E; Charlton, RK; Costa, MA; Desai, B; Guzman, LA; Shoemaker, SB; Yuan, H; Zenni, MM | 1 |
| Bednar, F; Móciková, H; Osmancik, PP | 1 |
| Biernat, M; Dropinski, J; Dziedzina, S; Jakiela, B; Plutecka, H; Sanak, M; Szczeklik, A; Wegrzyn, W | 1 |
| Bliden, KP; Chaganti, SK; Dichiara, J; Gesheff, TB; Gurbel, PA; Kreutz, RP; Kreutz, Y; Tantry, US | 1 |
| Bigalke, B; Dietz, K; Drosch, T; Gawaz, M; Geisler, T; Grass, D; Herdeg, C; Stellos, K | 1 |
| Hjemdahl, P; Hofman-Bang, C; Ivert, T; Li, N; Perneby, C; Tornvall, P; Wallén, NH | 1 |
| Alfonso, F; Angiolillo, DJ; Bass, TA; Bernardo, E; Desai, B; Fernandez-Ortiz, A; Guzman, LA; Hernández-Antolin, R; Macaya, C; Palazuelos, J; Weisberg, I; Zenni, MZ | 1 |
| Engelhardt, A; Lask, S; Mügge, A; Neubauer, H | 1 |
| Abbate, R; Caporale, R; Cesari, F; Gensini, GF; Gori, AM; Marcucci, R; Paniccia, R; Romano, E | 1 |
| Bouchard, D; Buluran, J; Cartier, R; Despatis, MA | 1 |
| Barnard, MR; Becker, RC; Benoit, SE; Borbone, ML; Furman, MI; Hechtman, HB; Michelson, AD; Valeri, CR | 1 |
| Bidouard, JP; Bruneval, P; Janiak, P; Perrault, LP; Vanhoutte, PM; Vilaine, JP; Villeneuve, N | 1 |
| Badimon, JJ; Chesebro, JH; Farkouh, ME; Fuster, V; Helft, G; Lev, EI; Osende, JI; Rodriguez, OJ; Worthley, SG; Zaman, AG | 1 |
| Duffy, SJ; Holbrook, M; Keaney, JF; Swerdloff, PL; Vita, JA | 1 |
| Blann, AD; Cazenave, JP; Galajda, P; Gurney, D; Lanza, F; Lip, GY; Moog, S | 1 |
| de Faire, U; Hamsten, A; Nilsson, J; Svensson, J | 1 |
| Gratsianskiĭ, NA; Men'shikov, MIu; Panchenko, EP; Shalaev, SV; Tkachuk, VA | 1 |
| Kartsev, AN; Lapotnikov, VA | 1 |
5 review(s) available for adenosine diphosphate and Coronary Artery Disease
| Article | Year |
|---|---|
Importance of measurement of platelet reactivity to ADP in patients with coronary artery disease: an historical account.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents | 2013 |
Platelet P2Y₁₂ receptor inhibition: an update on clinical drug development.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Design; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Receptors, Purinergic P2Y12; Ticlopidine | 2010 |
Ticagrelor: from discovery to Phase III clinical trial.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Clinical Trials, Phase III as Topic; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine | 2010 |
Translational platelet research in patients with coronary artery disease: what are the major knowledge gaps?
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Biomarkers, Pharmacological; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine; Translational Research, Biomedical; Treatment Outcome | 2012 |
The role of platelets in athero-thrombotic events.
Topics: Adenosine Diphosphate; Animals; Atherosclerosis; Blood Platelets; Coronary Artery Disease; Coronary Thrombosis; Fibrinolytic Agents; Hemostasis; Humans; Plaque, Atherosclerotic; Platelet Activation; Platelet Aggregation Inhibitors; Thrombin; Thrombosis; Thromboxane A2 | 2012 |
32 trial(s) available for adenosine diphosphate and Coronary Artery Disease
| Article | Year |
|---|---|
Impact of diabetes mellitus on the pharmacodynamic effects of prasugrel and ticagrelor after switching from clopidogrel in patients with coronary artery disease.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Ticagrelor | 2022 |
CD36+/CD61+ Microparticles Correlate with the Risk of Percutaneous Cardiac Interventions in Coronary Artery Disease Patients and the Effects of Ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticagrelor | 2022 |
Impact of Reticulated Platelets on the Antiplatelet Effect of the Intravenous P2Y12-Receptor Inhibitor Cangrelor.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Administration, Oral; Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thienopyridines; Ticagrelor | 2018 |
A high ratio of ADP-TRAP induced platelet aggregation is associated more strongly with increased mortality after coronary stent implantation than high conventional ADP induced aggregation alone.
Topics: Adenosine Diphosphate; Aged; Coronary Artery Disease; Female; Follow-Up Studies; Germany; Humans; Male; Myocardial Revascularization; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Complications; Prospective Studies; Receptors, Cell Surface; Stents; Survival Rate; Ticlopidine | 2014 |
Temporal variability in the antiplatelet effects of clopidogrel and aspirin after elective drug-eluting stent implantation. An ADAPT-DES substudy.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Elective Surgical Procedures; Female; Germany; Humans; Male; Middle Aged; Observer Variation; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Purinergic P2Y12; Ticlopidine | 2015 |
Ticagrelor versus prasugrel in patients with high on-clopidogrel treatment platelet reactivity after PCI: The ISAR-ADAPT-PF study.
Topics: Adenosine; Adenosine Diphosphate; Aged; Blood Platelets; Clopidogrel; Comorbidity; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome | 2016 |
Ticagrelor pharmacokinetics and pharmacodynamics in patients with NSTEMI after a 180-mg loading dose.
Topics: Adenosine; Adenosine Diphosphate; Aged; Biotransformation; Blood Platelets; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Non-ST Elevated Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Sweden; Ticagrelor | 2017 |
Effect of 150-mg vs 300-mg loading doses of clopidogrel on platelet function in Japanese patients undergoing coronary stent placement.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Asian People; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Dose-Response Relationship, Drug; Female; Humans; Japan; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug Resistance; Female; Flow Cytometry; Humans; Incidence; Male; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction; Ticlopidine | 2008 |
Comparison of collagen versus adenosine diphosphate in detecting antiplatelet effect in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Ticlopidine; Treatment Outcome | 2009 |
Considerable variability in platelet activity among patients with coronary artery disease in response to an increased maintenance dose of clopidogrel.
Topics: Adenosine Diphosphate; Aged; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine; Time Factors | 2009 |
Insights into the interpretation of light transmission aggregometry for evaluation of platelet aggregation inhibition by clopidogrel.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine | 2009 |
High loading dose of clopidogrel is unable to satisfactorily inhibit platelet reactivity in patients with glycoprotein IIIA gene polymorphism: a genetic substudy of PRAGUE-8 trial.
Topics: Adenosine Diphosphate; Aged; Antigens, Human Platelet; Clopidogrel; Coronary Artery Disease; Female; Humans; Integrin beta3; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine; Time Factors | 2009 |
The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients.
Topics: Adenosine Diphosphate; Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Coagulation; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Collagen; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Female; Gene Frequency; Genotype; Humans; Male; Microfilament Proteins; Middle Aged; Phenotype; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Purinergic P2 Receptor Antagonists; Quinazolinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Sulfonamides; Thrombelastography; Ticlopidine | 2010 |
Dose-related effect of aspirin on laboratory-defined platelet aggregation and clinical outcome after coronary stenting.
Topics: Adenosine Diphosphate; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Chi-Square Distribution; Coronary Artery Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Female; Humans; Iran; Male; Middle Aged; Myocardial Infarction; Myocardial Perfusion Imaging; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Assessment; Risk Factors; Sex Factors; Smoking; Stents; Time Factors; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2010 |
Comparison between the effect of omeprazole and rabeprazole on the antiplatelet action of clopidogrel.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabeprazole; Ticlopidine; Treatment Outcome | 2010 |
Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study.
Topics: Adenosine Diphosphate; Aspirin; Atorvastatin; Calcium Channel Blockers; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP3A; Drug Substitution; Drug Therapy, Combination; Female; Fluorobenzenes; Genotype; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Ticlopidine | 2012 |
Relation between clopidogrel active metabolite levels and different platelet aggregation methods in patients receiving clopidogrel and aspirin.
Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prodrugs; Ticlopidine; Time Factors | 2012 |
Effect of clopidogrel on platelet aggregation and plasma concentration of fibrinogen in subjects with cerebral or coronary atherosclerotic disease.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Clopidol; Collagen; Coronary Artery Disease; Family Health; Fibrinogen; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests | 2002 |
Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity.
Topics: Adenosine Diphosphate; Aged; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Resistance; Female; Flow Cytometry; Genetic Variation; Humans; Male; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine | 2003 |
Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination.
Topics: Adenosine Diphosphate; Antigens, Human Platelet; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Cytoplasmic Granules; Epinephrine; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Ticlopidine | 2006 |
Diabetes mellitus and platelet function after administration of aspirin and a single 600 mg dose of clopidogrel.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Diabetes Complications; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Thrombin; Thrombosis; Ticlopidine | 2006 |
Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance'.
Topics: Adenosine Diphosphate; Adult; Aspirin; Bayes Theorem; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Resistance; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Reference Values; Severity of Illness Index; Ticlopidine; Time Factors | 2007 |
No effect of oral hormone replacement therapy on platelet function in postmenopausal women with coronary artery disease.
Topics: Adenosine Diphosphate; Aged; beta-Thromboglobulin; Blood Platelets; Coronary Artery Disease; Cross-Over Studies; Double-Blind Method; Estradiol; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Follicle Stimulating Hormone; Humans; Leukocytes; Medroxyprogesterone Acetate; Middle Aged; P-Selectin; Platelet Adhesiveness; Platelet Function Tests; Postmenopause; Thrombin | 2006 |
Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease: results of the Optimizing Antiplatelet Therapy in Diabetes Mellitus (OPTIMUS) study.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine | 2007 |
The additive antiplatelet action of clopidogrel in patients with coronary artery disease treated with aspirin.
Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Biomarkers; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome | 2007 |
Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Collagen; Coronary Artery Disease; Cross-Over Studies; Double-Blind Method; Female; Fibrinogen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; von Willebrand Factor | 2007 |
Effect of clopidogrel treatment on stress-induced platelet activation and myocardial ischemia in aspirin-treated patients with stable coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; C-Reactive Protein; CD40 Ligand; Clopidogrel; Collagen; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Flow Cytometry; Heart Rate; Humans; Interleukin-6; Leukocytes; Male; Middle Aged; Myocardial Ischemia; P-Selectin; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Stress, Physiological; Thrombin; Ticlopidine; Treatment Outcome | 2007 |
Functional impact of high clopidogrel maintenance dosing in patients undergoing elective percutaneous coronary interventions. Results of a randomized study.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Florida; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Research Design; Spain; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2008 |
Relationship between high platelet turnover and platelet function in high-risk patients with coronary artery disease on dual antiplatelet therapy.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Arachidonic Acid; Blood Platelets; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Treatment Outcome | 2008 |
Acute antithrombotic effect of a front-loaded regimen of clopidogrel in patients with atherosclerosis on aspirin.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Fibrinogen; Fibrinolytic Agents; Humans; Perfusion; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors | 2000 |
Effect of acute and chronic tea consumption on platelet aggregation in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Coronary Artery Disease; Coronary Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Humans; Lipids; Male; Middle Aged; Peptide Fragments; Platelet Aggregation; Tea | 2001 |
71 other study(ies) available for adenosine diphosphate and Coronary Artery Disease
| Article | Year |
|---|---|
P
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Anti-Inflammatory Agents; Case-Control Studies; Coronary Artery Disease; Humans; Inflammation; Macrophages; Monocytes; Phosphorylation; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; THP-1 Cells | 2021 |
Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation.
Topics: Adenosine Diphosphate; Animals; Coronary Artery Disease; Feedback; Humans; Mice; Mitochondria; Mitogen-Activated Protein Kinase 7; Phenotype; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Ribose | 2021 |
Elevated serum C1q is an independent predictor of high residual platelet reactivity in CAD patients receiving clopidogrel therapy.
Topics: Adenosine; Adenosine Diphosphate; Clopidogrel; Complement C1q; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thrombosis; Ticagrelor; Ticlopidine | 2022 |
Leukocyte miR-223-3p is not associated with
altered platelet responses to clopidogrel in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Leukocytes; MicroRNAs; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2018 |
Effect of Physical Exercise on Platelet Reactivity in Patients with Dual Antiplatelet Therapy.
Topics: Adenosine Diphosphate; Aspirin; Chromogranin A; Clopidogrel; Coronary Artery Disease; Electrocardiography; Exercise; Exercise Tolerance; Humans; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Thrombosis; Ticlopidine | 2018 |
Correlation between serum adiponectin and risk factors in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Adiponectin; Aged; Angina Pectoris; C-Reactive Protein; Coronary Angiography; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Myocardial Infarction; Risk Factors | 2013 |
Impact of aspirin dose on adenosine diphosphate-mediated platelet activities. Results of an in vitro pilot investigation.
Topics: Adenosine Diphosphate; Aged; Aspirin; Cell Adhesion Molecules; Coronary Artery Disease; Drug Dosage Calculations; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Pilot Projects; Piperazines; Platelet Activation; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Thiophenes | 2013 |
Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Blood Platelets; Coronary Artery Disease; Coronary Thrombosis; Hemorrhage; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Stents | 2013 |
Response to antiplatelet therapy and platelet reactivity to thrombin receptor activating peptide-6 in cardiovascular interventions: Differences between peripheral and coronary angioplasty.
Topics: Adenosine Diphosphate; Aged; Angioplasty; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Monocytes; P-Selectin; Peptide Fragments; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Stents; Ticlopidine | 2014 |
Increased mean platelet volume is associated with non-responsiveness to clopidogrel.
Topics: Adenosine Diphosphate; Blood Platelets; Cells, Cultured; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Platelet Aggregation; Platelet Count; Platelet Function Tests; Ticlopidine | 2014 |
Evidence of platelet sensitization to ADP following discontinuation of clopidogrel therapy in patients with stable coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2015 |
Effects of cytochrome P450 2C19 and paraoxonase 1 polymorphisms on antiplatelet response to clopidogrel therapy in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aryldialkylphosphatase; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine | 2014 |
Low platelet activity predicts 30 days mortality in patients undergoing heart surgery.
Topics: Adenosine Diphosphate; Aged; Aortic Valve; Arachidonic Acid; Area Under Curve; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Erythrocyte Transfusion; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis; Thrombosis; Ticlopidine; Treatment Outcome | 2016 |
Relationship between high on aspirin platelet reactivity and oxidative stress in coronary artery by-pass grafted patients.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Coronary Artery Bypass; Coronary Artery Disease; Coronary Vessels; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Oxidative Stress; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2 | 2016 |
Platelet aggregation in response to ADP is highly variable in normal donors and patients on anti-platelet medication.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Case-Control Studies; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests | 2016 |
Parathyroid Hormone Levels and High-Residual Platelet Reactivity in Patients Receiving Dual Antiplatelet Therapy With Acetylsalicylic Acid and Clopidogrel or Ticagrelor.
Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Aged; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Databases, Factual; Drug Resistance; Drug Therapy, Combination; Female; Homeodomain Proteins; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticagrelor; Ticlopidine; Time Factors; Transcription Factors; Treatment Outcome; Up-Regulation | 2016 |
Platelet reactivity over time in coronary artery disease patients treated with a bioabsorbable everolimus-eluting scaffold.
Topics: Absorbable Implants; Adenosine Diphosphate; Adolescent; Adult; Aged; Aged, 80 and over; Biomimetic Materials; Blood Platelets; Coronary Artery Disease; Drug-Eluting Stents; Everolimus; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Pilot Projects; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Receptors, Purinergic P2; Receptors, Thromboxane A2, Prostaglandin H2; Signal Transduction; Tissue Scaffolds; Young Adult | 2016 |
Vitamin D levels and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Aged; Aged, 80 and over; Biomarkers; Blood Platelets; Clopidogrel; Comorbidity; Coronary Angiography; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Odds Ratio; Platelet Activation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine; Vitamin D | 2016 |
β-blockers are associated with decreased leucocyte-platelet aggregate formation and lower residual platelet reactivity to adenosine diphosphate after angioplasty and stenting.
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Aged; Angioplasty; Blood Platelets; Case-Control Studies; Cohort Studies; Coronary Artery Disease; Female; Flow Cytometry; Humans; Linear Models; Male; Middle Aged; Monocytes; Multivariate Analysis; Neutrophils; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Stents | 2016 |
The prevalence of the platelet glycoprotein IIIa Pl(A1/A2) polymorphism in three South African ethnic groups and its effect on platelet function.
Topics: Adenosine Diphosphate; Alleles; Blood Platelets; Collagen; Coronary Artery Disease; Dose-Response Relationship, Drug; Ethnicity; Female; Gene Frequency; Genotype; Humans; Integrin beta3; Male; Platelet Aggregation; Polymorphism, Genetic; Prevalence; South Africa; Thromboxane A2; Urban Population | 2008 |
Dual antiplatelet therapy unmasks distinct platelet reactivity in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Aspirin; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine | 2008 |
Analysis of platelet alpha2-adrenergic receptor activity in stable coronary artery disease patients on dual antiplatelet therapy.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic alpha-Antagonists; Aged; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Imidazoles; Male; Middle Aged; Norepinephrine; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Failure | 2008 |
Streamlining the design of promising clinical trials: in-vitro testing of antithrombotic regimens and multiple agonists of platelet activation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Clinical Trials as Topic; Coronary Artery Disease; Crotalid Venoms; Drug Evaluation, Preclinical; Drug Therapy, Combination; Eptifibatide; Fibrinolytic Agents; Flow Cytometry; Heparin; Hirudins; Humans; Lectins, C-Type; P-Selectin; Peptide Fragments; Peptides; Pilot Projects; Platelet Activating Factor; Platelet Activation; Platelet Function Tests; Recombinant Proteins; Research Design; Thrombin | 2009 |
Evaluation of the platelet count drop method for assessment of platelet function in comparison with "gold standard" light transmission aggregometry.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Reproducibility of Results; Ticlopidine | 2009 |
Clopidogrel and proton pump inhibitors: gastric protection at expense of vascular benefit?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine | 2009 |
Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Middle Aged; Multivariate Analysis; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine | 2009 |
Differences in responses of platelets to fluid shear stress in patients with peripheral artery disease (PAD) and coronary artery disease (CAD).
Topics: Adenosine Diphosphate; Arachidonic Acid; Collagen; Coronary Artery Disease; Epinephrine; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Peripheral Vascular Diseases; Platelet Activation; Platelet Aggregation; Stress, Mechanical | 2009 |
Hostility and platelet reactivity in individuals without a history of cardiovascular disease events.
Topics: Adenosine Diphosphate; Aggression; Blood Platelets; Cardiovascular Diseases; Coronary Artery Disease; Coronary Thrombosis; Coronary Vessels; Female; Hostility; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Platelet Count; Risk Factors | 2009 |
Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Risk Assessment; Risk Factors; ROC Curve; Severity of Illness Index; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Biotransformation; Blood Platelets; Cell Adhesion Molecules; Chromatography, Liquid; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Flow Cytometry; Humans; Linear Models; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Tandem Mass Spectrometry; Ticlopidine | 2010 |
Antiplatelet effect of 50-mg maintenance dose of clopidogrel compared to 200 mg ticlopidine: a preliminary study.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Asian People; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Japan; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
In vitro effects of recombinant activated factor VIIa (NovoSeven) on clopidogrel-induced platelet inhibition.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Clopidogrel; Coagulants; Collagen; Coronary Artery Disease; Factor VIIa; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Recombinant Proteins; Thrombin; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Oral anticoagulation with coumarin derivatives and antiplatelet effects of clopidogrel.
Topics: Adenosine Diphosphate; Administration, Oral; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multivariate Analysis; Phenprocoumon; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine | 2010 |
Evaluation of antiplatelet effects of a modified protocol by platelet aggregation in patients undergoing "one-stop" hybrid coronary revascularization.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; Ticlopidine | 2010 |
A comparison of the VerifyNow P2Y12 point-of-care device and light transmission aggregometry to monitor platelet function with prasugrel and clopidogrel: an integrated analysis.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Databases, Factual; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Prasugrel Hydrochloride; Thiophenes; Ticlopidine | 2010 |
Comparison of methods for monitoring residual platelet reactivity after clopidogrel by point-of-care tests on whole blood in high-risk patients.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Blood Platelets; Coronary Artery Disease; Drug Monitoring; Female; Humans; Italy; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Receptors, Purinergic P2Y12; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Stents; Thrombosis; Treatment Outcome | 2010 |
Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition of platelet aggregation after clopidogrel.
Topics: Adenosine Diphosphate; Adult; Area Under Curve; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Synergism; Humans; Male; Middle Aged; Platelet Aggregation; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Rifampin; Ticlopidine | 2010 |
Effect of 450-mg loading dose of clopidogrel on platelet function in Japanese patients undergoing coronary stent placement.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Asian People; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Japan; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2010 |
Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Blood Platelets; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2 Receptor Antagonists; Risk Factors; ROC Curve; Stents; Ticlopidine | 2010 |
Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Biomarkers; Blood Platelets; Case-Control Studies; Chi-Square Distribution; Collagen; Coronary Artery Disease; Denmark; Diabetes Mellitus, Type 2; Female; Humans; Linear Models; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Registries; Risk Assessment; Risk Factors; Smoking; Thrombopoietin; Thromboxane B2 | 2011 |
The cytochrome 2C19*2 and *3 alleles attenuate response to clopidogrel similarly in East Asian patients undergoing elective percutaneous coronary intervention.
Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Asian People; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Republic of Korea; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome | 2011 |
Light transmittance aggregometry induced by different concentrations of adenosine diphosphate to monitor clopidogrel therapy: a methodological study.
Topics: Adenosine Diphosphate; Angioplasty; Clopidogrel; Coronary Artery Disease; Drug Monitoring; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Point-of-Care Systems; Ticlopidine | 2011 |
Time dependence of clopidogrel loading effect: platelet activation versus platelet aggregation.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Annexin A5; Aspirin; Baltimore; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Stents; Ticlopidine; Time Factors; Treatment Outcome | 2012 |
Comparison of venous and arterial blood sampling for the assessment of platelet aggregation with whole blood impedance aggregometry.
Topics: Adenosine Diphosphate; Arachidonic Acid; Area Under Curve; Arteries; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Electric Impedance; Female; Humans; Male; Phlebotomy; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Specimen Handling; Ticlopidine; Veins | 2011 |
Effects of P2Y(1) receptor antagonism on the reactivity of platelets from patients with stable coronary artery disease using aspirin and clopidogrel.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Thrombin; Thrombosis; Ticlopidine | 2012 |
Impaired ATP-induced coronary blood flow and diminished aortic NTPDase activity precede lesion formation in apolipoprotein E-deficient mice.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta, Thoracic; Apolipoproteins E; Coronary Artery Disease; Coronary Circulation; Female; Hyperemia; Lymphatic System; Male; Mice; Mice, Inbred C57BL; Nucleoside-Triphosphatase; Receptors, Purinergic P2Y; Signal Transduction; Vasodilation; Vasodilator Agents | 2012 |
Fractalkine activates a signal transduction pathway similar to P2Y12 and is associated with impaired clopidogrel responsiveness.
Topics: Adenosine Diphosphate; Alprostadil; Chemokine CX3CL1; Clopidogrel; Coronary Artery Disease; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Signal Transduction; Ticlopidine | 2012 |
Platelet activating factor levels and metabolism in Tangier disease: a case study.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Adenosine Diphosphate; Adult; Aged; Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Assay; Blood Platelets; Coronary Artery Disease; Diacylglycerol Cholinephosphotransferase; Female; Humans; Middle Aged; Mutation; Platelet Activating Factor; Platelet Aggregation; Rabbits; Reference Values; Tangier Disease; Thrombin | 2012 |
Human platelet protease-activated receptor-1 responsiveness to thrombin related to P2Y12 inhibition.
Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptor, PAR-1; Receptors, Purinergic P2Y12; Thrombin; Thromboembolism; Ticlopidine; Translational Research, Biomedical | 2013 |
Biphasic effects of hemodialysis on platelet reactivity in patients with end-stage renal disease: a potential contributor to cardiovascular risk.
Topics: Adenosine Diphosphate; Coronary Artery Disease; Female; Fibrinogen; Flow Cytometry; Humans; Kidney Failure, Chronic; Male; Membranes, Artificial; Microscopy, Confocal; Middle Aged; Myocardial Infarction; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Renal Dialysis; Risk Factors | 2002 |
Low incidence of paradoxical platelet activation by glycoprotein IIb/IIIa inhibitors.
Topics: Abciximab; Adenosine Diphosphate; Adult; Antibodies, Monoclonal; Antigens, Human Platelet; Case-Control Studies; Coronary Artery Disease; Eptifibatide; Female; Genotype; Humans; Immunoglobulin Fab Fragments; Incidence; Integrin beta3; Male; Middle Aged; P-Selectin; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Tirofiban; Tyrosine | 2002 |
Association of aortic stenosis with platelet hyperaggregability and impaired responsiveness to nitric oxide.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aortic Valve Stenosis; Aspirin; Cardiovascular Agents; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitric Oxide; Nitroprusside; Perhexiline; Platelet Aggregation; Platelet Aggregation Inhibitors; Severity of Illness Index; Statistics as Topic; Stroke Volume; Ventricular Function, Left | 2002 |
Decreased platelet reactivity in blood anticoagulated with bivalirudin or enoxaparin compared with unfractionated heparin: implications for coronary intervention.
Topics: Adenosine Diphosphate; Aged; Anticoagulants; Coronary Artery Disease; Drug Evaluation; Enoxaparin; Flow Cytometry; Heparin; Hirudins; Humans; Middle Aged; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins | 2002 |
Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate.
Topics: Adenosine Diphosphate; Aged; Angina Pectoris; Aspirin; Blood Platelets; Case-Control Studies; Coronary Artery Disease; Drug Resistance; Dual Specificity Phosphatase 2; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Function Tests; Protein Phosphatase 2; Protein Tyrosine Phosphatases | 2002 |
Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction.
Topics: Adenosine Diphosphate; Aged; Aspirin; Biotransformation; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Epinephrine; Eptifibatide; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Prodrugs; Prospective Studies; Purinergic P2 Receptor Antagonists; Recurrence; Risk; Smoking; Stents; Ticlopidine; Treatment Outcome | 2004 |
Variation in the ability of glycoprotein IIb-IIIa antagonists to exert and maintain their inhibitory effects on the binding of fibrinogen.
Topics: Adenosine Diphosphate; Aged; Binding, Competitive; Blood Platelets; Clopidogrel; Coronary Artery Disease; Data Interpretation, Statistical; Eptifibatide; Fibrinogen; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Iodine Radioisotopes; Male; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Ticlopidine; Tirofiban; Tyrosine | 2005 |
Platelet activation predicts recurrent ischemic events after percutaneous coronary angioplasty: a 6 months prospective study.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Collagen; Coronary Artery Disease; Epinephrine; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Multivariate Analysis; Myocardial Ischemia; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Recurrence; Risk Factors; Survival Rate; Time Factors | 2006 |
Comparison of platelet fibronectin, ADP-induced platelet aggregation and serum total nitric oxide (NOx) levels in angiographically determined coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Angiography; Blood Platelets; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; Female; Fibronectins; Humans; Male; Middle Aged; Models, Statistical; Nitric Oxide; Platelet Aggregation; Prognosis; Triglycerides | 2006 |
Differential antiplatelet effects of angiotensin converting enzyme inhibitors: comparison of ex vivo platelet aggregation in cardiovascular patients with ramipril, captopril and enalapril.
Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Captopril; Cardiovascular Diseases; Clopidogrel; Collagen; Coronary Artery Disease; Electric Impedance; Enalapril; Female; Fibrinolytic Agents; Germany; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ramipril; Ticlopidine; Treatment Outcome | 2006 |
Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance.
Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Clopidogrel; Coronary Artery Disease; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Resistance; Female; Flow Cytometry; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Signal Transduction; Thrombosis; Thromboxane B2; Ticlopidine; Time Factors; Treatment Refusal | 2006 |
Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Thromboxane B2; Whole Blood Coagulation Time | 2006 |
Glycemia, triglycerides and disease severity are best associated with higher platelet activity in patients with stable coronary artery disease.
Topics: Adenosine Diphosphate; Aged; Blood Glucose; Coronary Artery Disease; Female; Humans; Male; Metabolic Syndrome; Middle Aged; P-Selectin; Platelet Activation; Platelet Membrane Glycoprotein IIb; Severity of Illness Index; Triglycerides | 2007 |
The Residual Platelet Aggregation after Deployment of Intracoronary Stent (PREDICT) score.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angina Pectoris; Clopidogrel; Cohort Studies; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Models, Statistical; Platelet Aggregation; Platelet Function Tests; Regression Analysis; Stents; Ticlopidine | 2008 |
How to optimise clopidogrel therapy? Reducing the low-response incidence by aggregometry-guided therapy modification.
Topics: Adenosine Diphosphate; Aged; Algorithms; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cardiovascular Diseases; Clinical Protocols; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Drug Resistance; Feasibility Studies; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Ticlopidine | 2008 |
Vascular effects of cyclosporin A and acute rejection in canine heart transplantation.
Topics: Acetylcholine; Acute Disease; Adenosine Diphosphate; Animals; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; Cyclosporine; Dinoprost; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Factor VIII; Graft Rejection; Heart Transplantation; Immunoenzyme Techniques; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardium; Nitroprusside; Serotonin; Thrombin; Transplantation, Heterotopic; Tunica Intima; Vasoconstriction; Vasodilation | 1997 |
Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease.
Topics: Adenosine Diphosphate; Adult; Angina Pectoris; Cell Adhesion; Cell Adhesion Molecules; Cell Count; Cell Degranulation; Cell Movement; Coronary Artery Disease; Coronary Disease; Coronary Vessels; Epinephrine; Female; Flow Cytometry; Humans; Leukocytes; Male; Middle Aged; Monocytes; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation; Receptors, Thrombin; Thrombosis | 1998 |
Impairment of G-protein-mediated signal transduction in the porcine coronary endothelium during rejection after heart transplantation.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Bradykinin; Calcimycin; Coronary Artery Disease; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Graft Rejection; GTP-Binding Proteins; Heart Transplantation; In Vitro Techniques; Ionophores; Male; Microscopy, Electron; Signal Transduction; Swine; Transplantation, Homologous | 1999 |
Increased platelet glycoprotein V levels in patients with coronary and peripheral atherosclerosis--the influence of aspirin and cigarette smoking.
Topics: Adenosine Diphosphate; Adult; Aged; Arteriosclerosis; Aspirin; beta-Thromboglobulin; Biomarkers; Cholesterol, HDL; Collagen; Coronary Artery Disease; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Epinephrine; Female; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Multivariate Analysis; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Risk Factors; Smoking | 2001 |
Increased platelet-derived mitogenic activity in plasma of young patients with coronary atherosclerosis.
Topics: Adenosine Diphosphate; Adult; alpha-Macroglobulins; beta-Thromboglobulin; Blood Platelets; Coronary Artery Disease; Coronary Vessels; Humans; Lipoproteins; Male; Middle Aged; Myocardial Infarction; Phenotype; Platelet Aggregation; Platelet Factor 4; Platelet-Derived Growth Factor | 1986 |
[Free cytoplasmic calcium and thrombocyte aggregation in patients with ischemic heart disease. The effect of ADP, thrombocyte activation factor and serotonin].
Topics: Adenosine Diphosphate; Adult; Angina Pectoris; Blood Platelets; Calcium; Coronary Artery Disease; Coronary Disease; Cytoplasm; Humans; Male; Middle Aged; Myocardial Infarction; Physical Exertion; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1986 |
[Thrombocyte reactivity of patients with hypertension and coronary atherosclerosis].
Topics: Adenosine Diphosphate; Blood Platelets; Coronary Artery Disease; Epinephrine; Humans; Hypertension; Platelet Aggregation | 1986 |