adenosine has been researched along with Trypanosomiasis, African in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Callens, M; Hannaert, V; Herdewijn, P; Hol, WG; Michels, PA; Opperdoes, FR; Van Aerschot, A; Van Calenbergh, S; Verlinde, CL | 1 |
| Bjorness, TE; Cox, KH; Greene, RW; Rijo-Ferreira, F; Sonneborn, A; Takahashi, JS | 1 |
| Cestari, I; Chen, J; Leija, C; Li, Q; Phillips, MA; Rijo-Ferreira, F; Stuart, K; Tu, BP | 1 |
| De Koning, HP; Dogruel, M; Rodgers, J; Sanderson, L; Thomas, SA | 1 |
| Brun, R; Heidler, P; Kaiser, M; Link, A | 1 |
| Barker, RH; Celatka, CA; Hirth, B; Klinger, JD; Liu, H; Nare, B; Nijjar, A; Phillips, MA; Sybertz, E; Willert, EK; Xiang, Y | 1 |
| Bacchi, CJ; Barker, RH; Hendrick, CL; Hirth, B; Rattendi, D; Rodriguez, A; Sybertz, E; Yarlett, N | 1 |
| Al-Salabi, MI; Augustyns, K; Berg, M; Castagna, V; Cos, P; de Koning, HP; Degano, M; Giannese, F; Grellier, P; Haemers, A; Joossens, J; Kohl, L; Maes, L; Steyaert, J; Van der Veken, P; Versées, W | 1 |
| TOBIE, EJ | 1 |
| GRAY, AR; STEPHEN, LE | 1 |
| Anderson, LF; Barrett, MP; Burchmore, RJ; de Koning, HP; Stewart, M; Wallace, LJ | 1 |
| Heby, O; Persson, L; Rentala, M | 1 |
| Allison, AC; Dube, DK; Lederer, E; Mpimbaza, G; Rovis, L | 1 |
| Kaminsky, R; Kralli, A; Mäser, P; Sütterlin, C | 1 |
| Enyaru, JC; Gallati, S; Geiser, F; Kaminsky, R; Mäser, P; Matovu, E; Schneider, V; Seebeck, T | 1 |
| Bacchi, CJ; Quamina, A; Yarlett, N | 1 |
| Kaufmann, W; Röttcher, D; Schillinger, D; Zweygarth, E | 1 |
1 review(s) available for adenosine and Trypanosomiasis, African
| Article | Year |
|---|---|
Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Chagas Disease; Eflornithine; Enzyme Inhibitors; Glutathione; Humans; Leishmania; Leishmaniasis; Ornithine Decarboxylase Inhibitors; Robenidine; Spermidine; Spermidine Synthase; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African | 2007 |
16 other study(ies) available for adenosine and Trypanosomiasis, African
| Article | Year |
|---|---|
Selective inhibition of trypanosomal glyceraldehyde-3-phosphate dehydrogenase by protein structure-based design: toward new drugs for the treatment of sleeping sickness.
Topics: Adenosine; Animals; Binding Sites; Deoxyadenosines; Drug Design; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Bonding; Leishmania mexicana; Molecular Structure; NAD; Protein Conformation; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosomiasis, African | 1994 |
Sleeping Sickness Disrupts the Sleep-Regulating Adenosine System.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Electroencephalography; Electromyography; Electrophysiological Phenomena; Gene Expression; Homeostasis; Male; Mice; Mice, Inbred C57BL; Receptor, Adenosine A2A; Sleep; Sleep Deprivation; Trypanosoma brucei brucei; Trypanosomiasis, African | 2020 |
GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway.
Topics: Adenosine; Animals; Binding Sites; Carbon-Nitrogen Ligases; Cell Cycle; Gene Knockout Techniques; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine; Metabolic Networks and Pathways; Mice, Inbred C57BL; Purines; Recombinant Proteins; Trypanosoma brucei brucei; Trypanosomiasis, African | 2015 |
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein.
Topics: Adenine; Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Disease Models, Animal; Drug Interactions; Eflornithine; Indomethacin; Male; Melarsoprol; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Multidrug Resistance-Associated Proteins; Nifurtimox; Pentamidine; Perfusion; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 2009 |
Synthesis of a series of N6-substituted adenosines with activity against trypanosomatid parasites.
Topics: Adenosine; Animals; Inhibitory Concentration 50; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2009 |
Discovery of new S-adenosylmethionine decarboxylase inhibitors for the treatment of Human African Trypanosomiasis (HAT).
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Blood-Brain Barrier; Drug Discovery; Humans; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2009 |
Trypanocidal activity of 8-methyl-5'-{[(Z)-4-aminobut-2-enyl]-(methylamino)}adenosine (Genz-644131), an adenosylmethionine decarboxylase inhibitor.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Dogs; Random Allocation; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2009 |
Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis.
Topics: Adenosine; Animals; Antiprotozoal Agents; Carrier Proteins; Gene Knockdown Techniques; Melarsoprol; Mice; Models, Chemical; N-Glycosyl Hydrolases; Pentamidine; RNA, Small Interfering; Trypanosoma brucei brucei; Trypanosomiasis, African | 2010 |
The trypanocidal effect of nucleocidin in vivo.
Topics: Adenosine; Anti-Bacterial Agents; Trypanosomiasis; Trypanosomiasis, African | 1957 |
The trypanocidal activity of nucleocidin against Trypanosoma vivax in West African zebu cattle.
Topics: Adenosine; Animals; Anti-Bacterial Agents; Cattle; Trypanosoma vivax; Trypanosomiasis; Trypanosomiasis, African | 1960 |
The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.
Topics: Adenosine; Animals; Biological Transport, Active; Diminazene; Drug Resistance; Female; Kinetics; Mutation; Nucleoside Transport Proteins; Rats; Rats, Wistar; Saccharomyces cerevisiae; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2004 |
Antitrypanosomal activity of sinefungin.
Topics: Adenosine; Animals; Male; Mice; Mice, Inbred BALB C; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
A nucleoside transporter from Trypanosoma brucei involved in drug resistance.
Topics: Adenosine; Amino Acid Sequence; Animals; Arsenicals; Biological Transport; Carrier Proteins; Cloning, Molecular; Drug Resistance; Genes, Protozoan; Membrane Proteins; Molecular Sequence Data; Mutation; Nucleoside Transport Proteins; Nucleosides; Purines; Saccharomyces cerevisiae; Substrate Specificity; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1999 |
Genetic variants of the TbAT1 adenosine transporter from African trypanosomes in relapse infections following melarsoprol therapy.
Topics: Adenosine; Animals; Carrier Proteins; Cerebrospinal Fluid; Drug Resistance; Genetic Variation; Humans; Melarsoprol; Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Recurrence; Sequence Analysis, DNA; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2001 |
Protein methylases in Trypanosoma brucei brucei: activities and response to DL-alpha-difluoromethylornithine.
Topics: Adenosine; Animals; Binding Sites; Binding, Competitive; Eflornithine; Histone-Lysine N-Methyltransferase; Hydrogen-Ion Concentration; Kinetics; Methylation; Protein O-Methyltransferase; Protein-Arginine N-Methyltransferases; Rats; Substrate Specificity; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
Evaluation of sinefungin for the treatment of Trypanosoma (Nannomonas) congolense infections in goats.
Topics: Adenosine; Animals; Drug Administration Schedule; Drug Evaluation; Female; Goats; Kidney; Male; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Urea | 1986 |