adenosine has been researched along with Severe Combined Immunodeficiency in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Bertoni, A; Cafaro, A; Cangemi, G; Caorsi, R; Gattorno, M; Penco, F; Schena, F; Signa, S; Volpi, S | 1 |
| Chen, F; Dong, L; He, L; Lamy, T; Lei, W; Luo, W; Zavialov, AV; Zhou, Q | 1 |
| Lee, PY | 1 |
| Blackburn, MR; Bogdanov, MV; Dowhan, W; Idowu, M; Juneja, HS; Kellems, RE; Li, J; Molina, JG; Song, A; Sun, K; Wu, H; Xia, Y; Zhang, Y | 1 |
| Gonçalves, P; Krenn, G; Peaudecerf, L; Rocha, B; Vasseur, F | 1 |
| Cao, Q; Dong, G; Dong, XP; Pandey, A; Rainey, JK; Sun, X; Zhong, XZ; Zhu, X; Zou, Y | 1 |
| Bonfante-Cabarcas, R; Goncalves, L; Ibarra, A; Pérez-Aguilar, MC | 1 |
| Azzari, C; la Marca, G; Resti, M | 1 |
| Aiuti, A; Brigida, I; Carlucci, F; Carriglio, N; Clavenna, D; Gagliani, N; Hernandez, RJ; Poliani, PL; Roncarolo, MG; Sanvito, F; Sauer, AV; Scaramuzza, S; Tabucchi, A; Traggiai, E; Villa, A | 1 |
| Gaspar, HB; Montiel-Equihua, CA; Thrasher, AJ | 1 |
| Biaggioni, I; Blackburn, MR; Feoktistov, I; Goldstein, AE; Novitskiy, SV; Ryzhov, S | 1 |
| Hershfield, MS | 1 |
| Blackburn, MR; Datta, SK; Kellems, RE | 1 |
| Fujita, T; Higashino, K; Moriwaki, Y; Ohta, S; Shimizu, K; Shioda, M; Shiota, M; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T | 1 |
| Apasov, SG; Sitkovsky, MV | 1 |
| Koshiba, M | 1 |
| Aldrich, MB; Blackburn, MR; Kellems, RE | 1 |
| Apasov, S; Chen, JF; Sitkovsky, M; Smith, P | 1 |
| Aldrich, M; Blackburn, MR; Chen, W; Datta, SK; Hershfield, MS; Kellems, RE; Kelly, S; Volmer, JB; Zhong, H | 1 |
| Apasov, SG; Blackburn, MR; Kellems, RE; Sitkovsky, MV; Smith, PT | 1 |
| Aldrich, MB; Blackburn, MR; Datta, SK; Kellems, RE | 1 |
| Franco, R | 1 |
8 review(s) available for adenosine and Severe Combined Immunodeficiency
| Article | Year |
|---|---|
Adenosine Deaminase 2 Deficiency (DADA2): A Crosstalk Between Innate and Adaptive Immunity.
Topics: Adaptive Immunity; Adenosine; Adenosine Deaminase; Agammaglobulinemia; Endothelial Cells; Humans; Intercellular Signaling Peptides and Proteins; Polyarteritis Nodosa; Severe Combined Immunodeficiency | 2022 |
Thymocytes self-renewal: a major hope or a major threat?
Topics: Adenosine; Animals; Cell Self Renewal; Clonal Selection, Antigen-Mediated; Humans; Immune Tolerance; Interleukin-7; Mice; Mice, SCID; Severe Combined Immunodeficiency; T-Lymphocytes; Thymocytes; Thymus Gland; Transplantation, Homologous | 2016 |
[Adenosine deaminase as costimulatory molecule and marker of cellular immunity].
Topics: Adenosine; Adenosine Deaminase; Agammaglobulinemia; Cell Hypoxia; Communicable Diseases; Dendritic Cells; Dipeptidyl Peptidase 4; Enzyme Induction; Female; Hepatitis, Viral, Human; Humans; Hypertension, Pregnancy-Induced; Immunity, Cellular; Immunological Synapses; Inflammation Mediators; Interferon-gamma; Interleukins; Isoenzymes; Lymphocyte Activation; Pregnancy; Receptors, Purinergic P1; Severe Combined Immunodeficiency; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2010 |
Gene therapy for severe combined immunodeficiency due to adenosine deaminase deficiency.
Topics: Adenosine; Adenosine Deaminase; Agammaglobulinemia; Clinical Trials as Topic; Genetic Therapy; Genetic Vectors; Humans; Lentivirus; Mutagenesis, Insertional; Neurons; Severe Combined Immunodeficiency | 2012 |
New insights into adenosine-receptor-mediated immunosuppression and the role of adenosine in causing the immunodeficiency associated with adenosine deaminase deficiency.
Topics: Adenosine; Adenosine Deaminase; Animals; Deoxyadenosines; Humans; Immune Tolerance; Infant; Lymphocytes; Mice; Mice, Knockout; Models, Immunological; Receptors, Purinergic P1; Severe Combined Immunodeficiency | 2005 |
[Roles of the cell surface purinergic receptors for extracellular adenosine and ATP in T-cell development and effector functions].
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Cell Differentiation; Humans; Receptors, Purinergic; Severe Combined Immunodeficiency; T-Lymphocytes | 1999 |
The importance of adenosine deaminase for lymphocyte development and function.
Topics: Adenosine; Adenosine Deaminase; Animals; Deoxyadenosines; Disease Models, Animal; Humans; Lymphocytes; Mice; Severe Combined Immunodeficiency | 2000 |
Adenosine deaminase-deficient mice: models for the study of lymphocyte development and adenosine signaling.
Topics: Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Deoxyadenosines; Disease Models, Animal; Humans; Hydrolases; Lymphocytes; Mice; Mice, Knockout; Receptor, Adenosine A3; Receptors, Purinergic P1; Severe Combined Immunodeficiency; Signal Transduction | 2000 |
1 trial(s) available for adenosine and Severe Combined Immunodeficiency
| Article | Year |
|---|---|
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adolescent; Adult; Agammaglobulinemia; Animals; Antigens, CD; Apyrase; Autoantibodies; Child; Child, Preschool; Female; Forkhead Transcription Factors; Genetic Therapy; Hematopoietic Stem Cell Transplantation; Humans; Hypothyroidism; Immunohistochemistry; Infant; Male; Mice; Mice, Knockout; Polyethylene Glycols; Severe Combined Immunodeficiency; T-Lymphocytes, Regulatory | 2012 |
13 other study(ies) available for adenosine and Severe Combined Immunodeficiency
| Article | Year |
|---|---|
ELISA based assays to measure adenosine deaminases concentration in serum and saliva for the diagnosis of ADA2 deficiency and cancer.
Topics: Adenosine; Adenosine Deaminase; Agammaglobulinemia; Enzyme-Linked Immunosorbent Assay; Humans; Intercellular Signaling Peptides and Proteins; Neoplasms; Polyarteritis Nodosa; Saliva; Severe Combined Immunodeficiency | 2022 |
NETing the mechanism of inflammation in DADA2.
Topics: Adenosine; Adenosine Deaminase; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Severe Combined Immunodeficiency | 2019 |
Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Agammaglobulinemia; Anemia, Sickle Cell; Animals; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Erythrocytes; Erythrocytes, Abnormal; Hemoglobin, Sickle; Humans; MAP Kinase Signaling System; Mice; Mice, Knockout; Mice, Transgenic; Models, Biological; Phosphotransferases (Alcohol Group Acceptor); Receptor, Adenosine A2B; Severe Combined Immunodeficiency; Signal Transduction | 2015 |
Inhibition of Transient Receptor Potential Channel Mucolipin-1 (TRPML1) by Lysosomal Adenosine Involved in Severe Combined Immunodeficiency Diseases.
Topics: Adenosine; Adenosine Deaminase; Calcium; Cell Line; Gene Deletion; HEK293 Cells; Humans; Lymphocytes; Lysosomes; Severe Combined Immunodeficiency; Transient Receptor Potential Channels | 2017 |
Neonatal screening for severe combined immunodeficiency caused by an adenosine deaminase defect: a reliable and inexpensive method using tandem mass spectrometry.
Topics: Adenosine; Adenosine Deaminase; Agammaglobulinemia; Blood Chemical Analysis; Case-Control Studies; Child; Child, Preschool; Costs and Cost Analysis; Deoxyadenosines; Female; Humans; Infant; Infant, Newborn; Italy; Male; Neonatal Screening; Pilot Projects; Reproducibility of Results; Sensitivity and Specificity; Severe Combined Immunodeficiency; Tandem Mass Spectrometry | 2011 |
Role of A2B adenosine receptors in regulation of paracrine functions of stem cell antigen 1-positive cardiac stromal cells.
Topics: Adenosine; Adenosine Deaminase; Agammaglobulinemia; Animals; Antigens, Ly; Cells, Cultured; Chemokine CXCL1; Female; Interleukin-6; Male; Membrane Proteins; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocardial Infarction; Myocardium; Paracrine Communication; Platelet Endothelial Cell Adhesion Molecule-1; Receptor, Adenosine A2B; RNA, Messenger; Severe Combined Immunodeficiency; Stem Cells; Up-Regulation; Vascular Endothelial Growth Factor A | 2012 |
Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency.
Topics: Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Antigens, CD; Antigens, Differentiation; B-Lymphocytes; Bone and Bones; Deoxyadenosines; Genetic Engineering; Hydrolases; Kidney; Lung; Lymphocyte Count; Lymphopenia; Mice; Pulmonary Valve Insufficiency; Purine-Pyrimidine Metabolism, Inborn Errors; Research Design; Severe Combined Immunodeficiency; Spleen; T-Lymphocytes; Thymus Gland; Tissue Distribution | 1998 |
Determination of adenosine and deoxyadenosine in urine by high-performance liquid chromatography with column switching.
Topics: Adenosine; Adenosine Deaminase; Adult; Bone Marrow Transplantation; Chromatography, High Pressure Liquid; Deoxyadenosines; Fructose; Heterozygote; Homozygote; Humans; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Severe Combined Immunodeficiency | 1998 |
The extracellular versus intracellular mechanisms of inhibition of TCR-triggered activation in thymocytes by adenosine under conditions of inhibited adenosine deaminase.
Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Apoptosis; Biological Transport; CD3 Complex; GTP-Binding Proteins; Lymphocyte Activation; Mice; Mice, Inbred DBA; Mice, Transgenic; Receptors, Antigen, T-Cell; Severe Combined Immunodeficiency; T-Lymphocytes; Thymus Gland | 1999 |
A(2A) receptor dependent and A(2A) receptor independent effects of extracellular adenosine on murine thymocytes in conditions of adenosine deaminase deficiency.
Topics: Adenosine; Adenosine Deaminase; Animals; Cells, Cultured; Cyclic AMP; Flow Cytometry; Lymphocyte Depletion; Mice; Mice, Inbred DBA; Mice, Knockout; Phenethylamines; Receptor, Adenosine A2A; Receptors, Antigen, T-Cell; Receptors, Purinergic P1; Severe Combined Immunodeficiency; T-Lymphocytes; Thymus Gland | 2000 |
The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities.
Topics: Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Deoxyadenine Nucleotides; Deoxyadenosines; Disease Models, Animal; Genotype; Histocytochemistry; Hydrolases; Killer Cells, Natural; Lung; Lymphocyte Count; Lymphocytes; Lymphopenia; Mice; Mice, Transgenic; Phenotype; S-Adenosylhomocysteine; Severe Combined Immunodeficiency; Spleen; Thymus Gland | 2000 |
Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling.
Topics: Adenosine; Adenosine Deaminase; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Apoptosis; B-Lymphocytes; Calcium Signaling; Cell Differentiation; Cells, Cultured; Deoxyadenine Nucleotides; Deoxyadenosines; Gene Expression Regulation; Lectins, C-Type; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Knockout; Mice, SCID; Organ Specificity; Phosphorylation; Protein Processing, Post-Translational; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Interleukin-2; Severe Combined Immunodeficiency; Signal Transduction; Specific Pathogen-Free Organisms; Spleen; T-Lymphocytes; Thymus Gland | 2001 |
New possibilities in the therapy of immunodeficiency diseases.
Topics: Adenosine; Adenosine Deaminase; Animals; Humans; Inosine; Severe Combined Immunodeficiency | 1991 |