adenosine has been researched along with Pancreatic Neoplasms in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (15.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (16.98) | 24.3611 |
| 2020's | 36 (67.92) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, W; Sun, M; Wang, Y; Xia, L; Xie, M; Zhang, T | 1 |
| Chen, JQ; Hong, YG; Hu, LK; Huang, ZP; Li, HF; Tao, YP; Xu, XF; Zheng, H | 1 |
| Gan, D; Guo, Y; Hua, L; Li, J; Li, S; Liu, X; Ma, P; Min, J; Shi, J; Song, Y; Su, H; Wang, R; Yang, C; Zhang, C; Zhao, T; Zhu, L | 1 |
| Li, F; Zhang, P | 1 |
| Cao, L; Ding, G; Huang, C; Jia, S; Jin, Y; Pang, T; Xu, G; Zhang, C; Zhou, L; Zhou, S | 1 |
| Dzubak, P; Hajduch, M; Kotulova, J; Kourilova, P; Kubickova, A; Lonova, K; Vrbkova, J | 1 |
| Chen, J; Han, S; Hu, Y; Huang, M; Huang, Y; Tang, J; Wang, D; Wang, F; Xu, F; Zeng, Z; Zhao, G; Zhao, Y; Zhuo, W | 1 |
| Fang, Z; Kong, J; Liu, J; Liu, Y; Wang, T | 1 |
| Hua, J; Lei, Y; Liang, C; Liu, X; Meng, Q; Shi, S; Tan, Z; Wang, W; Xu, J; Yu, X; Zhang, B | 1 |
| Chen, S; Chen, ZW; Hu, JF; Huang, L; Huang, Y; Liao, CY; Pan, JJ; Shen, BY; Tian, YF; Wang, YD; Wang, ZW; Yang, C; Zhang, JQ | 1 |
| Jiang, Z; Kong, D; Li, Y; Song, X; Sun, J; Wei, Y | 1 |
| Akita, H; Chijimatsu, R; Doki, Y; Eguchi, H; Ishii, H; Kobayashi, S; Konno, M; Mitsufuji, S; Motooka, D; Murakumo, Y; Ogawa, K; Tamari, K; Tatekawa, S | 1 |
| Jiang, Y; Sheng, P; Zhang, T | 1 |
| Chang, L; Chen, S; Ren, H; Ren, J; Wang, Z; Wu, H; Zhang, J; Zhang, X; Zhou, L | 1 |
| Chen, LJ; He, Y; Tang, ZG; Wang, W; Wu, L; Yao, LC; Yu, KH; Zhai, LL | 1 |
| Gao, G; Tang, Y; Wang, JB; Xia, WW | 1 |
| Allard, B; Allard, D; Bareche, Y; Chrobak, P; Cousineau, I; Eeles, CB; Haibe-Kains, B; Jacoberger-Foissac, C; Koseoglu, S; Lake, AC; Masia, R; McNicoll, Y; Messaoudi, N; Pommey, S; Robson, SC; Rohatgi, N; Seo, H; Soucy, G; Stagg, J; Turcotte, S | 1 |
| Bailey-Lundberg, JM; Bar-Sagi, D; Brown, PH; Bynon, JS; Chandra, V; Clark, T; Dai, Y; Eltzschig, HK; Faraoni, EY; Le Roux, O; Li, L; McAllister, F; Mills, T; Mohammed, A; O'Brien, BJ; Poulsen, KL; Pruski, M; Sahin, I; Savage, MI; Sei, S; Singh, K; Strickland, LN; Thosani, NC; Van Buren, G; Vornik, LA; Vucic, E; Warner, AN; Wray, CJ; Zhao, Z | 1 |
| Chen, H; Cheng, J; Du, J; Fu, J; He, T; Zhang, L; Zhang, W | 1 |
| Guo, Z; Huang, Y; Lai, S; Li, T; Lin, C; Wang, Y; Weng, S; Zhang, X | 1 |
| Hu, L; Jiang, S; Li, B; Li, R; Zhang, X; Zhang, Y; Zhang, Z; Zhu, L | 1 |
| Bailey-Lundberg, JM; Eltzschig, HK; Faraoni, EY; Ruan, W; Strickland, LN; Yuan, X | 1 |
| Han, X; Huang, X; Liang, T; Lu, M; Tang, T; Zhang, G | 1 |
| Brais, R; Buckley, H; Dannhorn, A; Dovedi, SJ; Eyles, J; Goodwin, R; Graziano, V; Hulme, H; Islam, S; Jodrell, DI; Kaistha, BP; Karim, SA; Lee, SY; Morton, JP; Richards, FM; Schuller, AG; Thaventhiran, JED; Williamson, K; Wilson, M | 1 |
| Bai, J; Chen, J; Gong, Z; Gu, D; Hu, C; Lu, F; Tang, Q; Tian, Y; Wang, Y; Xu, L; Yan, L; Ye, M; Yu, P | 1 |
| Che, Z; Chu, Y; Liu, F; Liu, J; Ma, Y; McGrath, M; Song, C; Wu, L; Wu, M; Xu, W; Yang, D; Zhang, Q; Zhang, W | 1 |
| Hackert, T; Roth, S | 1 |
| Hu, X; Huang, D; Jiang, J; Mo, YY; Peng, WX; Yang, L; Zhou, H; Zhou, X | 1 |
| Feng, Y; Guo, X; Hu, Y; Huang, Y; Jiang, W; Li, K; Pan, Q; Wan, R; Xiao, W | 1 |
| Chang, J; He, H; Li, B; Li, Y; Miao, X; Peng, X; Tian, J; Wang, H; Wang, X; Yang, N; Ying, P; Zhong, R; Zhu, Y; Zou, D | 1 |
| Chen, W; Fung, KM; He, Y; Houchen, CW; Li, M; Li, X; Liu, M; Luo, W; McNally, LR; Shi, X; Xu, C; Yang, J; Zhan, H; Zhang, C; Zhang, J; Zhang, Y; Zhou, Z | 1 |
| Guo, W; He, Y; Yu, X; Zhang, Q; Zheng, Q | 1 |
| Bai, Z; Chai, R; Jin, L; Kou, T; Wu, D; Yang, Y; Zhang, Z; Zhao, Y | 1 |
| Li, L; Li, S; Ren, J; Shang, D; Xiang, K; Yuan, Q | 1 |
| Li, J; Liu, Y; Ni, B; Wang, F; Wang, H | 1 |
| Gao, ZX; Huang, CS; Huang, XT; Li, JH; Xu, QC; Yin, XY; Zhao, W; Zhu, XX | 1 |
| Li, H; Li, T; Shen, J; Wang, L; Wu, Q; Xu, Y; Zhang, S | 1 |
| Bai, R; Chen, R; Deng, J; Huang, J; Huang, X; Li, M; Lin, D; Liu, K; Pan, L; Su, J; Wei, L; Wu, G; Ye, Y; Zeng, L; Zhang, J; Zhang, S; Zheng, J; Zheng, Y; Zhuang, L | 1 |
| Akiva, E; Gorzalczany, Y; Klein, O; Merimsky, O; Sagi-Eisenberg, R | 1 |
| Cruz-Monserrate, Z; Govindarajan, R; Griffin, J; Hung, SW; Mody, HR; Pathak, RK | 1 |
| Chen, H; Cheng, Q; Huang, R; Li, S; Qian, Y; Shao, Z; Wang, H; Xiang, M; Xie, R; Xu, N; Xu, Q; Zhou, Z | 1 |
| Bai, R; Che, X; Chen, R; Fu, Z; Jia, W; Li, G; Li, M; Li, S; Lin, D; Liu, Z; Mai, D; Pan, L; Su, J; Tan, L; Tan, W; Wang, C; Wu, C; Xie, D; Xu, RH; Ye, H; Ye, Y; Zeng, MS; Zhang, J; Zhao, Q; Zheng, J; Zheng, S; Zheng, Y; Zuo, Z | 1 |
| Bhutia, YD; Cho, JH; Chu, CK; Davis, F; Dhar, S; Govindarajan, R; Hung, SW; Marrache, S; Mody, H; Zastre, J | 1 |
| AlSaggar, M; Govindarajan, R; Griffin, J; Hung, SW; Mody, HR | 1 |
| Avan, A; Crea, F; Danesi, R; Funel, N; Galvani, E; Giovannetti, E; Honeywell, RJ; Marquez, VE; Paolicchi, E; Peters, GJ | 1 |
| Leibiger, B; Leibiger, IB; Schwarz, T; Walther, R | 1 |
| Agarwal, KC; Tzanakakis, GN; Vezeridis, MP | 1 |
| Malaisse, WJ; Rasschaert, J; Tanigawa, K | 1 |
| Figarella, C; Merten, M; Montserrat, C | 1 |
| Chen, ZH; Olopade, OI; Savarese, TM | 1 |
| Cabantchik, ZI; Eidelman, O; Fox, C; Guay-Broder, C; Jacobson, KA; Pollard, HB; Turner, RJ; van Galen, PJ | 1 |
| Carroll, PB; Fontes, P; Fung, JJ; Phipps, J; Ricordi, C; Rilo, HR; Starzl, TE; Tzakis, AG | 1 |
| Alfani, D; Berloco, P; Bruzzone, P; Caricato, M; Casciaro, G; Cortesini, R; Iappelli, M; Marciani, A; Rossi, M; Urbano, D | 1 |
3 review(s) available for adenosine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Research advances of N6-methyladenosine in diagnosis and therapy of pancreatic cancer.
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Humans; Methyltransferases; Pancreatic Neoplasms; Repressor Proteins; RNA, Messenger | 2022 |
The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer.
Topics: Adenosine; CD8-Positive T-Lymphocytes; Humans; Hypoxia; Immunotherapy; Pancreatic Neoplasms; Receptor, Adenosine A2B; Tumor Microenvironment | 2023 |
N
Topics: Adenosine; Biomarkers, Tumor; Carcinogenesis; Disease Progression; Humans; Pancreatic Neoplasms; Prognosis; RNA, Messenger | 2021 |
50 other study(ies) available for adenosine and Pancreatic Neoplasms
| Article | Year |
|---|---|
m
Topics: Adenosine; Biomarkers, Tumor; Cluster Analysis; Databases, Genetic; Decision Support Techniques; Gene Expression Profiling; Humans; Immunotherapy; Models, Genetic; Pancreatic Neoplasms; Prognosis; RNA Processing, Post-Transcriptional; Transcriptome; Tumor Microenvironment | 2021 |
M
Topics: Adenosine; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia Inhibitory Factor Receptor alpha Subunit; Methyltransferases; MicroRNAs; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA, Long Noncoding; Signal Transduction; Up-Regulation; Vascular Endothelial Growth Factor A | 2021 |
Comprehensive Analysis of m6A RNA Methylation Regulators and the Immune Microenvironment to Aid Immunotherapy in Pancreatic Cancer.
Topics: Adenocarcinoma; Adenosine; Biomarkers, Tumor; Cohort Studies; Databases, Genetic; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Kaplan-Meier Estimate; Methylation; Pancreatic Neoplasms; Prognosis; RNA; Transcriptome; Tumor Microenvironment | 2021 |
The N6-Methyladenosine- (m6A-) Associated Genes Act as Strong Key Biomarkers for the Prognosis of Pancreatic Adenocarcinoma.
Topics: Adenocarcinoma; Adenosine; Biomarkers, Tumor; Computational Biology; Databases, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Male; Methylation; Pancreatic Neoplasms; Prognosis; Proportional Hazards Models; Protein Interaction Maps; RNA-Binding Proteins | 2021 |
ZC3H13-mediated N6-methyladenosine modification of PHF10 is impaired by fisetin which inhibits the DNA damage response in pancreatic cancer.
Topics: Adenosine; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Flavonols; Homeodomain Proteins; Humans; Neoplasm Proteins; Nuclear Proteins; Pancreatic Neoplasms; Rad51 Recombinase; Recombinational DNA Repair; RNA-Binding Proteins; Tumor Suppressor p53-Binding Protein 1 | 2022 |
2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines.
Topics: Adenosine; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Resistance; Hedgehog Proteins; Humans; Liver Neoplasms; Pancreatic Neoplasms; Zinc Finger Protein GLI1 | 2022 |
A reciprocal feedback between N6-methyladenosine reader YTHDF3 and lncRNA DICER1-AS1 promotes glycolysis of pancreatic cancer through inhibiting maturation of miR-5586-5p.
Topics: Adenosine; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; DEAD-box RNA Helicases; Glycolysis; Humans; Pancreatic Neoplasms; Ribonuclease III; RNA-Binding Proteins; RNA, Long Noncoding; Transfection | 2022 |
Analysis of N6-methyladenosine-related lncRNAs in the tumor immune microenvironment and their prognostic role in pancreatic cancer.
Topics: Adenosine; Biomarkers, Tumor; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Neoplasms; Prognosis; RNA, Long Noncoding; Tumor Microenvironment | 2022 |
RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Humans; Lymphokines; Pancreatic Neoplasms; Platelet-Derived Growth Factor; RNA; RNA-Binding Proteins; RNA, Messenger | 2022 |
SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing promotes resistance of pancreatic cancer to gemcitabine.
Topics: Adenosine; Alternative Splicing; Deoxycytidine; DNA; Gemcitabine; Humans; Pancreatic Neoplasms; RNA, Long Noncoding; Serine-Arginine Splicing Factors | 2022 |
N(6)-methyladenosine-mediated miR-380-3p maturation and upregulation promotes cancer aggressiveness in pancreatic cancer.
Topics: Adenosine; Cell Line, Tumor; Cell Proliferation; Humans; Methyltransferases; MicroRNAs; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; Up-Regulation | 2022 |
N(6)-methyladenosine methylation-regulated polo-like kinase 1 cell cycle homeostasis as a potential target of radiotherapy in pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Adenosine; Cell Cycle; Cell Cycle Proteins; Homeostasis; Humans; Methylation; Methyltransferases; Pancreatic Neoplasms; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA-Binding Proteins | 2022 |
m6A regulators are differently expressed and correlated with immune response of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Adenosine; Cell Line, Tumor; Datasets as Topic; Humans; Lymphocytes; Macrophages; Methylation; Neutrophils; Pancreatic Neoplasms; RNA Processing, Post-Transcriptional; RNA, Messenger | 2023 |
N
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Cell Movement; Extracellular Matrix; Humans; Pancreatic Neoplasms | 2023 |
METTL3 promotes the growth and metastasis of pancreatic cancer by regulating the m6A modification and stability of E2F5.
Topics: Adenosine; E2F5 Transcription Factor; Humans; Methyltransferases; Pancreatic Neoplasms; RNA, Messenger; Sincalide | 2022 |
CD73 Inhibits cGAS-STING and Cooperates with CD39 to Promote Pancreatic Cancer.
Topics: 5'-Nucleotidase; Adenosine; Animals; Apyrase; CD8-Positive T-Lymphocytes; Cell Line; Humans; Mice; Pancreatic Neoplasms | 2023 |
CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer.
Topics: 5'-Nucleotidase; Adenosine; Animals; Cancer Vaccines; Carcinoma, Pancreatic Ductal; Humans; Immunosuppression Therapy; Immunotherapy; Mice; Pancreatic Neoplasms; Tumor Microenvironment | 2023 |
Effect of DPP4/CD26 expression on SARS‑CoV‑2 susceptibility, immune response, adenosine (derivatives m
Topics: Adenocarcinoma; Adenosine; Carcinoma, Hepatocellular; COVID-19; Dipeptidyl Peptidase 4; Female; Humans; Immunity; Liver Neoplasms; Male; Melanoma; Melanoma, Cutaneous Malignant; Pancreatic Neoplasms; Pandemics; Prospective Studies; SARS-CoV-2; Skin Neoplasms | 2023 |
METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation.
Topics: Adenosine; Animals; Carcinoma, Pancreatic Ductal; DEAD-box RNA Helicases; Gemcitabine; Humans; Lung Neoplasms; Methylation; Methyltransferases; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger | 2023 |
METTL3 suppresses pancreatic ductal adenocarcinoma progression through activating endogenous dsRNA-induced anti-tumor immunity.
Topics: Adenosine; Carcinoma, Pancreatic Ductal; Humans; Methyltransferases; Pancreatic Neoplasms; RNA, Double-Stranded; Tumor Microenvironment | 2023 |
Transcriptional control of pancreatic cancer immunosuppression by metabolic enzyme CD73 in a tumor-autonomous and -autocrine manner.
Topics: 5'-Nucleotidase; Adenosine; Cell Line, Tumor; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Pancreatic Neoplasms; Proteomics; Tumor Microenvironment | 2023 |
Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
Topics: Adenosine; Animals; Carcinoma, Pancreatic Ductal; Humans; Immunotherapy; Mice; Pancreatic Neoplasms; Tumor Microenvironment | 2023 |
ALKBH5 enhances lipid metabolism reprogramming by increasing stability of FABP5 to promote pancreatic neuroendocrine neoplasms progression in an m6A-IGF2BP2-dependent manner.
Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Fatty Acid-Binding Proteins; Humans; Lipid Metabolism; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; RNA-Binding Proteins; TOR Serine-Threonine Kinases | 2023 |
Augmenting the therapeutic efficacy of adenosine against pancreatic cancer by switching the Akt/p21-dependent senescence to apoptosis.
Topics: Adenosine; Animals; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cellular Senescence; Disease Models, Animal; Gene Silencing; Humans; Immunohistochemistry; Mice; Pancreatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; ras Proteins; Xenograft Model Antitumor Assays | 2019 |
Adenosine in pancreatic cancer: Emerging combination therapies.
Topics: Adenosine; Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Models, Animal; Disease Susceptibility; Humans; Mice; Pancreatic Neoplasms; Xenograft Model Antitumor Assays | 2019 |
IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader.
Topics: Adenosine; Animals; Cell Line, Tumor; Cell Proliferation; Humans; Mice; Mice, Inbred BALB C; Mice, Knockout; Pancreatic Neoplasms; RNA-Binding Proteins; RNA, Long Noncoding | 2020 |
RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner.
Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Animals; Apoptosis; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Pancreatic Neoplasms; Period Circadian Proteins; Prognosis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; Survival Rate; Transcriptional Activation; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Identification of genetic variants in m
Topics: 3' Untranslated Regions; Adenosine; Asian People; Carcinoma, Pancreatic Ductal; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Knockdown Techniques; Genetic Variation; Genotype; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; MicroRNAs; Pancreatic Neoplasms; Polymorphism, Single Nucleotide | 2021 |
An integrated model of N6-methyladenosine regulators to predict tumor aggressiveness and immune evasion in pancreatic cancer.
Topics: Adenosine; Area Under Curve; Carcinoma, Pancreatic Ductal; Databases, Factual; DNA Copy Number Variations; Female; Humans; Immune Checkpoint Proteins; Immunotherapy; Male; Middle Aged; Pancreatic Neoplasms; Proportional Hazards Models; ROC Curve; Severity of Illness Index; Survival Analysis | 2021 |
Genetic characteristics and prognostic implications of m1A regulators in pancreatic cancer.
Topics: Adenocarcinoma; Adenosine; AlkB Homolog 1, Histone H2a Dioxygenase; Biomarkers, Tumor; Computational Biology; Humans; Pancreatic Neoplasms; Polymorphism, Single Nucleotide; RNA Processing, Post-Transcriptional | 2021 |
Systematic analysis of molecular characterization and clinical relevance of m6A regulators in digestive system pan-cancers.
Topics: Adenosine; Biomarkers, Tumor; Digestive System; Digestive System Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Neoplasms; Tumor Microenvironment | 2021 |
Development and validation of a novel N6-methyladenosine (m6A)-related multi- long non-coding RNA (lncRNA) prognostic signature in pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Adenosine; Aged; Cohort Studies; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Pancreatic Neoplasms; Prognosis; Risk Factors; RNA, Long Noncoding; Signal Transduction | 2021 |
HNRNPC impedes m
Topics: Adenosine; Alternative Splicing; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Transcription Factor TFIID | 2021 |
Quantification of m6A RNA methylation modulators pattern was a potential biomarker for prognosis and associated with tumor immune microenvironment of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Adenosine; Aged; Biomarkers, Tumor; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Lymphocytes, Tumor-Infiltrating; Male; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Prognosis; RNA; ROC Curve; Tumor Microenvironment | 2021 |
Topics: Adenosine; Animals; Apoptosis; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Cycle Proteins; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Prognosis; Protein Biosynthesis; RNA Splicing Factors; RNA, Long Noncoding; Survival Rate; Transcriptional Activation; Tumor Cells, Cultured; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2021 |
Mast cells are directly activated by contact with cancer cells by a mechanism involving autocrine formation of adenosine and autocrine/paracrine signaling of the adenosine A3 receptor.
Topics: A549 Cells; Adenosine; Autocrine Communication; Cell Membrane; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-8; Lung Neoplasms; Mast Cells; Pancreatic Neoplasms; Paracrine Communication; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, Adenosine A3; RNA Interference; Signal Transduction; Time Factors; Transfection; Tumor Microenvironment | 2017 |
miR-202 Diminishes TGFβ Receptors and Attenuates TGFβ1-Induced EMT in Pancreatic Cancer.
Topics: Adenosine; Animals; Capecitabine; Cell Line, Tumor; Deoxycytidine; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Lentivirus; Mice; MicroRNAs; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays | 2017 |
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.
Topics: Adenocarcinoma; Adenosine; Animals; Bone Marrow Cells; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Culture Media, Conditioned; Dendritic Cells; Epigenesis, Genetic; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Biological; Pancreatic Neoplasms; Phenylurea Compounds; Signal Transduction; Thiostrepton; Wnt-5a Protein | 2019 |
Excessive miR-25-3p maturation via N
Topics: Adenosine; Adult; Aged; Aged, 80 and over; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Transformation, Neoplastic; Co-Repressor Proteins; Disease Progression; DNA Methylation; Epithelial Cells; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Male; Methyltransferases; MicroRNAs; Middle Aged; Nicotiana; Nuclear Proteins; Pancreatic Ducts; Pancreatic Neoplasms; Phosphoprotein Phosphatases; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Repressor Proteins; Ribosomal Protein S6 Kinases, 70-kDa; RNA-Binding Proteins; Smoke; Smoking; Up-Regulation | 2019 |
Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies.
Topics: Adenosine; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Delayed-Action Preparations; Deoxycytidine; DNA Methylation; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Nanoparticles; Nucleosides; Pancreatic Neoplasms; Xenopus | 2013 |
Inhibition of S-Adenosylmethionine-Dependent Methyltransferase Attenuates TGFβ1-Induced EMT and Metastasis in Pancreatic Cancer: Putative Roles of miR-663a and miR-4787-5p.
Topics: Adenosine; Animals; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Histones; Humans; Methyltransferases; Mice; MicroRNAs; Pancreatic Neoplasms; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays | 2016 |
Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells.
Topics: AC133 Antigen; Adenosine; Antigens, CD; Antimetabolites, Antineoplastic; Apoptosis; Cadherins; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Line, Tumor; Cell Movement; Deoxycytidine; Drug Synergism; Enhancer of Zeste Homolog 2 Protein; Equilibrative Nucleoside Transporter 1; Gemcitabine; Gene Expression; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Membrane Transport Proteins; Pancreatic Neoplasms; Peptides; Polycomb Repressive Complex 2; Spheroids, Cellular; Tumor Cells, Cultured | 2012 |
Functional analysis of a newly identified TAAT-box of the rat insulin-II gene promoter.
Topics: Adenosine; Animals; Base Sequence; Binding Sites; Cell Line; DNA; Gene Expression Regulation; Homeodomain Proteins; Insulin; Insulinoma; Molecular Sequence Data; Pancreatic Neoplasms; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Rats, Wistar; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1995 |
Prevention of human pancreatic cancer cell-induced hepatic metastasis in nude mice by dipyridamole and its analog RA-233.
Topics: Adenosine; Animals; Dipyridamole; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Liver Neoplasms; Mice; Mice, Nude; Mopidamol; Pancreatic Neoplasms; Platelet Aggregation; Tumor Cells, Cultured | 1993 |
Deleterious effect of formycin A on tumor islet cells.
Topics: Adenoma, Islet Cell; Adenosine; Animals; Antineoplastic Agents; Formycins; Insulin; Insulin Secretion; Pancreatic Neoplasms; Proteins; Tumor Cells, Cultured | 1995 |
Defective ATP-dependent mucin secretion by cystic fibrosis pancreatic epithelial cells.
Topics: Adenocarcinoma; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens; Calcium; Carbachol; Cell Line; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Immunoassay; Mucins; Pancreatic Neoplasms; Receptors, Purinergic P2; Transfection; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis.
Topics: Adenosine; Antimalarials; Antimetabolites, Antineoplastic; Azaserine; Biomarkers, Tumor; Cell Count; Deoxyadenosines; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Methionine; Methotrexate; Pancreatic Neoplasms; Purine-Nucleoside Phosphorylase; Purines; RNA, Messenger; Thionucleosides; Tumor Cells, Cultured | 1997 |
A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells.
Topics: 2-Chloroadenosine; Adenocarcinoma; Adenosine; Cell Line; Chlorides; Chromosome Deletion; Colonic Neoplasms; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genotype; Humans; Kinetics; Membrane Proteins; Mutation; Pancreatic Neoplasms; Phenotype; Purinergic Antagonists; Xanthines | 1992 |
Microbiologic surveillance as part of human islet transplantation: results of the first 26 patients.
Topics: Adenosine; Allopurinol; Cell Separation; Colony Count, Microbial; Diabetes Mellitus, Type 1; Drug Contamination; Glutathione; Humans; Insulin; Islets of Langerhans Transplantation; Organ Preservation Solutions; Pancreatic Neoplasms; Postoperative Complications; Pseudomonas; Raffinose; Solutions; Staphylococcus | 1992 |
Multiple abdominal visceral transplantation: clinical experience of organ preservation by University of Wisconsin (UW) solution.
Topics: Adenoma, Bile Duct; Adenosine; Adult; Allopurinol; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Duodenal Neoplasms; Duodenum; Female; Glutathione; Humans; Insulin; Intestine, Small; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Organ Preservation; Organ Preservation Solutions; Pancreas Transplantation; Pancreatic Neoplasms; Raffinose; Solutions | 1991 |