Page last updated: 2024-08-24

adenosine and Neuralgia

adenosine has been researched along with Neuralgia in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.89)18.7374
1990's3 (7.89)18.2507
2000's12 (31.58)29.6817
2010's11 (28.95)24.3611
2020's9 (23.68)2.80

Authors

AuthorsStudies
Bhattarai, A; Bhola, R; Carlsson, J; Chia, LY; Christie, MJ; Christopoulos, A; Cowie-Kent, I; Danev, R; Draper-Joyce, CJ; Glukhova, A; Imlach, WL; May, LT; Miao, Y; Nguyen, ATN; O'Sullivan, K; Panel, N; Scammells, P; Sexton, PM; Thal, DM; Valant, C; Venugopal, H; Wang, J; White, PJ; Wootten, D1
Chang, H; Fang, Y; Guo, Y; Wu, J; Zhang, D; Zhou, M1
Dai, QX; Li, S; Lin, FH; Mo, YC; Ni, XQ; Ren, M; Wang, JL; Wu, X; Yao, XY1
Tang, H; Wu, L1
Jeong, W; Jun, IG; Kim, K; Park, JY1
Giancotti, LA; Jacobson, KA; Lauro, F; Mufti, F; Salvemini, D1
Aghamohammadi, D; Dolatkhah, N; Esmaeilinejad, A; Eydi, M; Pishgahi, A1
Assumpção, JAF; Caumo, W; Cioato, SG; de Souza, A; Lopes, BC; Medeiros, HR; Medeiros, LF; Roesler, R; Torres, ILS1
Albik, S; Bekker, A; Cao, M; Du, S; Feng, X; Fu, G; Huang, T; Tao, YX; Wu, S1
Chang, CH; Hsieh, ST; Hsieh, YL; Kan, HW; Lee, YC; Lin, CL1
Cuzzocrea, S; Doyle, T; Esposito, E; Jacobson, KA; Janes, K; Salvemini, D; Tosh, DK1
Bannister, K; Chen, Z; Dickenson, AH; Doyle, T; Ford, A; Jacobson, KA; Janes, K; Little, JW; Luongo, L; Maione, S; Porreca, F; Salvemini, D; Symons-Liguori, AM; Tosh, DK; Vanderah, TW; Xie, J1
Jacobson, KA; Padia, J; Salvemini, D; Tosh, DK1
Dussor, G; Fields, HL; Gutierrez, T; King, T; Lai, J; Porreca, F; Vanderah, TW; Vera-Portocarrero, L1
Cui, Y; Gong, QJ; Li, YY; Liu, CC; Liu, XG; Liu, Y; Wang, J; Wei, XH; Xin, WJ1
Zylka, MJ1
Burnstock, G; Fredholm, BB; Verkhratsky, A1
Bianco, MR; Cavaliere, C; Cirillo, G; Marcello, L; Merizzi, G; Papa, M; Petrosino, V; Soleti, A1
Horiuchi, H; Miura, H; Morino, T; Ogata, T; Yamaoka, G1
Cappellacci, L; de Novellis, V; Franchetti, P; Gatta, L; Giordano, C; Grifantini, M; Guida, F; Luongo, L; Maione, S; Petrelli, R; Vita, P1
Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J1
Aslantas, A; Dokmeci, I; Firat, Z; Karadag, HC; Tamer, M; Ulugol, A1
Liu, XJ; Sawynok, J; White, TD1
Clark, AJ; Lynch, ME; Sawynok, J1
PIVA, S2
Curry, R; Eisenach, JC; Rauck, RL1
Collins, SD; Danhof, M; de Boer, AG; DeJongh, J; Ijzerman, AP; Schaddelee, MP1
Clark, AJ; Lynch, ME; Sawynok, J; Sullivan, MJ1
Buechler, NL; Eisenach, JC; Kim, SA; Martin, TJ; Porreca, F1
Coderre, TJ; Gilron, I1
Belfrage, M; Hansson, P; Segerdahl, M; Sjölund, KF; Sollevi, A1
Belfrage, M; Hansson, P; Lundeberg, T; Segerdahl, M; Sollevi, A1
Bechis, G; Gola, R; Guieu, R; Hassani, H; Peragut, JC; Rochat, H; Roussel, P; Sampieri, F1
Hao, JX; Sollevi, A; von Heijne, M; Xu, XJ1
Arnér, S; Belfrage, M; Gordh, T; Karlsten, R; Segerdahl, M; Sjölund, KF; Solevi, A1
Conklin, D; Eisenach, JC; Li, X; Ma, W; Zhu, X1
Alexander, EJ; Blue, WT; Bodian, CA; Sklar, SH1

Reviews

5 review(s) available for adenosine and Neuralgia

ArticleYear
Adenosine signaling mediate pain transmission in the central nervous system.
    Purinergic signalling, 2023, Volume: 19, Issue:1

    Topics: Adenosine; Analgesics; Central Nervous System; Humans; Neuralgia; Pain, Postoperative; Quality of Life

2023
The role of N6-methyladenosine modification in rodent models of neuropathic pain: from the mechanism to therapeutic potential.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 166

    Topics: Adenosine; Animals; Chronic Pain; Neuralgia; Rodentia

2023
Pain-relieving prospects for adenosine receptors and ectonucleotidases.
    Trends in molecular medicine, 2011, Volume: 17, Issue:4

    Topics: 5'-Nucleotidase; Acid Phosphatase; Acupuncture Therapy; Adenosine; Adenosine Monophosphate; Analgesics; Animals; Humans; Hyperalgesia; Inflammation; Neuralgia; Nociceptors; Protein Tyrosine Phosphatases; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Recombinant Proteins

2011
Adenosine and ATP receptors in the brain.
    Current topics in medicinal chemistry, 2011, Volume: 11, Issue:8

    Topics: Adenosine; Adenosine Triphosphate; Animals; Brain; Dogs; Epilepsy; Female; Gene Expression; Humans; Ischemia; Mice; Neuralgia; Neuroglia; Neurons; Neurotransmitter Agents; Parkinson Disease; Rabbits; Rats; Receptors, Purinergic P1; Receptors, Purinergic P2; Synaptic Transmission

2011
Emerging drugs in neuropathic pain.
    Expert opinion on emerging drugs, 2007, Volume: 12, Issue:1

    Topics: Adenosine; Analgesics; Analgesics, Opioid; Animals; Anticonvulsants; Cannabinoids; Catecholamines; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Excitatory Amino Acid Antagonists; Humans; Neuralgia; Nicotinic Agonists; Nicotinic Antagonists; TRPV Cation Channels

2007

Trials

6 trial(s) available for adenosine and Neuralgia

ArticleYear
Pilot prospective open-label one-arm trial investigating intrathecal Adenosine in neuropathic pain after lumbar discectomy.
    BMC research notes, 2020, Jun-12, Volume: 13, Issue:1

    Topics: Adenosine; Adult; Aged; Analgesics; Diskectomy; Female; Follow-Up Studies; Humans; Injections, Spinal; Lumbar Vertebrae; Male; Middle Aged; Neuralgia; Pain, Postoperative; Pilot Projects; Prospective Studies; Severity of Illness Index; Spinal Nerve Roots; Treatment Outcome

2020
Intravenous adenosine alleviates neuropathic pain: a double blind placebo controlled crossover trial using an enriched enrolment design.
    Pain, 2003, Volume: 103, Issue:1-2

    Topics: Adenosine; Adult; Analgesics; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cross-Over Studies; Double-Blind Method; Humans; Hyperalgesia; Infusions, Intravenous; Middle Aged; Neuralgia; Pain; Pain Measurement; Pain Threshold; Placebos; Sensation; Sensory Thresholds; Time; Time Factors; Treatment Outcome

2003
Intrathecal, but not intravenous adenosine reduces allodynia in patients with neuropathic pain.
    Pain, 2003, Volume: 105, Issue:1-2

    Topics: Adenosine; Adult; Analgesics; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Male; Middle Aged; Neuralgia; Pain Measurement

2003
Topical amitriptyline and ketamine in neuropathic pain syndromes: an open-label study.
    The journal of pain, 2005, Volume: 6, Issue:10

    Topics: Adenosine; Administration, Topical; Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Drug Combinations; Female; Humans; Ketamine; Male; Middle Aged; Neuralgia; Pain Measurement; Pain Threshold; Patient Satisfaction; Peripheral Nervous System Diseases; Prospective Studies; Receptors, N-Methyl-D-Aspartate; Treatment Outcome

2005
Systemic adenosine infusion alleviates spontaneous and stimulus evoked pain in patients with peripheral neuropathic pain.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:4

    Topics: Adenosine; Adult; Analgesics; Cross-Over Studies; Double-Blind Method; Female; Humans; Infusions, Intravenous; Middle Aged; Neuralgia; Pain Measurement; Pain Threshold; Sensory Thresholds

1995
Systemic adenosine infusion reduces the area of tactile allodynia in neuropathic pain following peripheral nerve injury: a multi-centre, placebo-controlled study.
    European journal of pain (London, England), 2001, Volume: 5, Issue:2

    Topics: Adenosine; Adult; Aged; Aged, 80 and over; Analgesics; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyperalgesia; Male; Middle Aged; Neuralgia; Placebos; Treatment Outcome

2001

Other Studies

27 other study(ies) available for adenosine and Neuralgia

ArticleYear
Positive allosteric mechanisms of adenosine A
    Nature, 2021, Volume: 597, Issue:7877

    Topics: Adenosine; Allosteric Regulation; Analgesia; Animals; Binding Sites; Disease Models, Animal; Female; GTP-Binding Protein alpha Subunit, Gi2; Hyperalgesia; Lipids; Male; Neuralgia; Protein Stability; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Signal Transduction

2021
Analgesia with 5' extracellular nucleotidase-mediated electroacupuncture for neuropathic pain.
    Arquivos de neuro-psiquiatria, 2022, Volume: 80, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Analgesia; Animals; Electroacupuncture; Neuralgia; Nucleotidases; Rats; Rats, Sprague-Dawley; Spinal Cord

2022
Antiallodynic and anti-inflammatory effects of intrathecal R-PIA in a rat model of vincristine-induced peripheral neuropathy.
    Korean journal of anesthesiology, 2020, Volume: 73, Issue:5

    Topics: Adenosine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; Male; Neuralgia; Neuroprotective Agents; Physical Stimulation; Rats; Rats, Sprague-Dawley; Vincristine

2020
Treatment of chronic neuropathic pain: purine receptor modulation.
    Pain, 2020, Volume: 161, Issue:7

    Topics: Adenosine; Chronic Pain; Humans; Neuralgia; Receptors, Purinergic; Structure-Activity Relationship

2020
Antinociceptive and neurochemical effects of a single dose of IB-MECA in chronic pain rat models.
    Purinergic signalling, 2020, Volume: 16, Issue:4

    Topics: Adenosine; Analgesics; Animals; Chronic Pain; Disease Models, Animal; Inflammation; Male; Neuralgia; Rats; Rats, Wistar

2020
FTO (Fat-Mass and Obesity-Associated Protein) Participates in Hemorrhage-Induced Thalamic Pain by Stabilizing Toll-Like Receptor 4 Expression in Thalamic Neurons.
    Stroke, 2021, Volume: 52, Issue:7

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Cerebral Hemorrhage; Gene Knockdown Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microinjections; Neuralgia; Neurons; Thalamus; Toll-Like Receptor 4

2021
Downregulation of adenosine and adenosine A1 receptor contributes to neuropathic pain in resiniferatoxin neuropathy.
    Pain, 2018, Volume: 159, Issue:8

    Topics: Adenosine; Animals; Diterpenes; Down-Regulation; Ganglia, Spinal; Mice; Neuralgia; Neurons; Neurotoxins; Pain Measurement; Receptor, Adenosine A1; Small Fiber Neuropathy

2018
A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.
    Pain, 2014, Volume: 155, Issue:12

    Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Antineoplastic Agents, Phytogenic; Cytokines; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Hyperalgesia; Male; NADP; Neuralgia; Neuroglia; NF-kappa B; Oxidation-Reduction; Paclitaxel; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord; Tumor Necrosis Factor-alpha

2014
Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states.
    Brain : a journal of neurology, 2015, Volume: 138, Issue:Pt 1

    Topics: Adenosine; Animals; Disease Models, Animal; Gene Expression Regulation; Hyperalgesia; Male; Medulla Oblongata; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Naloxone; Neuralgia; Neurons; Pain Measurement; Pain Threshold; Purinergic P1 Receptor Antagonists; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Spinal Cord; Time Factors

2015
Efficient, large-scale synthesis and preclinical studies of MRS5698, a highly selective A3 adenosine receptor agonist that protects against chronic neuropathic pain.
    Purinergic signalling, 2015, Volume: 11, Issue:3

    Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Biological Transport, Active; Blood Proteins; Caco-2 Cells; Chronic Disease; Constriction, Pathologic; Half-Life; Humans; In Vitro Techniques; Male; Microsomes, Liver; Mutagenicity Tests; Neuralgia; Protein Binding; Rats; Rats, Sprague-Dawley

2015
Unmasking the tonic-aversive state in neuropathic pain.
    Nature neuroscience, 2009, Volume: 12, Issue:11

    Topics: Adenosine; Analgesics; Analysis of Variance; Animals; Calcium Channel Blockers; Clonidine; Conditioning, Classical; Conditioning, Psychological; Disease Models, Animal; Drug Administration Schedule; Hyperalgesia; Injections, Spinal; Male; Neuralgia; omega-Conotoxins; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Time Factors

2009
Differential effects of adenosine A1 receptor on pain-related behavior in normal and nerve-injured rats.
    Brain research, 2010, Nov-18, Volume: 1361

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Drug Administration Schedule; Electric Stimulation; Electrophysiology; Escape Reaction; Injections, Intraperitoneal; Long-Term Potentiation; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Nerves; Xanthines

2010
Neuropathic pain and reactive gliosis are reversed by dialdehydic compound in neuropathic pain rat models.
    Neuroscience letters, 2012, Nov-14, Volume: 530, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Aldehydes; Analgesics; Animals; Astrocytes; Chronic Disease; Disease Models, Animal; Drug Discovery; Gliosis; Hyperalgesia; Lumbar Vertebrae; Male; Microglia; Neuralgia; Rats; Rats, Sprague-Dawley; Spinal Cord

2012
Different analgesic effects of adenosine between postoperative and neuropathic pain.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2013, Volume: 18, Issue:1

    Topics: Adenosine; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Neuralgia; Pain, Postoperative; Rats; Rats, Wistar

2013
5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions.
    Molecules (Basel, Switzerland), 2012, Nov-22, Volume: 17, Issue:12

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Cardiovascular System; Humans; Hyperalgesia; Mice; Microglia; Motor Activity; Neuralgia; Neuroglia; Norbornanes; Receptor, Adenosine A1; Sciatic Nerve; Xanthines

2012
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
    Neuroscience, 2013, Mar-27, Volume: 234

    Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase Inhibitors; Animals; Caffeine; Exercise Therapy; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Neuralgia; Neurons; Reflex Sympathetic Dystrophy; Swimming; Triazines; Triazoles; Xanthines

2013
Involvement of adenosine in the anti-allodynic effect of amitriptyline in streptozotocin-induced diabetic rats.
    Neuroscience letters, 2002, Aug-09, Volume: 328, Issue:2

    Topics: Adenosine; Amitriptyline; Analgesics; Animals; Antidepressive Agents, Tricyclic; Caffeine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Interactions; Female; Hyperalgesia; Neuralgia; Nociceptors; Pain Measurement; Pain Threshold; Peripheral Nerves; Phosphodiesterase Inhibitors; Physical Stimulation; Rats; Rats, Sprague-Dawley

2002
Enhanced release of adenosine in rat hind paw following spinal nerve ligation: involvement of capsaicin-sensitive sensory afferents.
    Neuroscience, 2002, Volume: 114, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Afferent Pathways; Animals; Capsaicin; Disease Models, Animal; Enzyme Inhibitors; Hyperalgesia; Male; Nerve Crush; Nerve Fibers, Unmyelinated; Neuralgia; Neurons, Afferent; Nociceptors; Oxidopamine; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Skin; Spinal Nerves; Sympathetic Fibers, Postganglionic

2002
[Clinical use of a combination of adenosine triphosphoric acid (ATP), cocarboxylase, vitamin B12 and nicotinamide (PP) in the therapy of neuralgia and neuritis].
    Le Scalpel, 1960, May-28, Volume: 113

    Topics: Adenine Nucleotides; Adenosine; Humans; Neuralgia; Neuritis; Niacin; Niacinamide; Nicotinic Acids; Polyphosphates; Thiamine Pyrophosphate; Vitamin B 12

1960
[On the clinical use of a combination of adenosine-triphosphoric acid, (A.T.P.), cocarboxylase, vitamin B12 and nicotinamide (vitamin PP) in the therapy of neuralgia and neuritis].
    Gazzetta medica italiana, 1959, Volume: 118

    Topics: Adenine Nucleotides; Adenosine; Neuralgia; Neuritis; Niacin; Niacinamide; Nicotinic Acids; Polyphosphates; Thiamine Pyrophosphate; Vitamin B 12

1959
Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain.
    European journal of pharmacology, 2005, May-09, Volume: 514, Issue:2-3

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Algorithms; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Deoxyadenosines; Hyperalgesia; Injections, Intravenous; Male; Neuralgia; Rats; Time Factors

2005
Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics.
    Anesthesiology, 2007, Volume: 106, Issue:2

    Topics: Adenosine; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Fentanyl; Heroin; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Male; Methadone; Morphine; Neuralgia; Pain; Rats; Rats, Inbred F344; Self Administration

2007
Systemic adenosine infusion: a new treatment modality to alleviate neuropathic pain.
    Pain, 1995, Volume: 61, Issue:1

    Topics: Adenosine; Adult; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neuralgia; Pilot Projects

1995
Adenosine and neuropathic pain.
    Pain, 1996, Volume: 68, Issue:2-3

    Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Humans; Male; Middle Aged; Neuralgia

1996
Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats.
    European journal of pain (London, England), 2001, Volume: 5, Issue:1

    Topics: Adenosine; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclofen; Behavior, Animal; Clonidine; Female; GABA Agonists; Injections, Spinal; Ischemia; Morphine; Neuralgia; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sodium Chloride; Spinal Cord

2001
Spinal noradrenergic activation mediates allodynia reduction from an allosteric adenosine modulator in a rat model of neuropathic pain.
    Pain, 2002, Volume: 97, Issue:1-2

    Topics: Adenosine; Adrenergic alpha-Antagonists; Allosteric Regulation; Animals; Dopamine beta-Hydroxylase; Idazoxan; Immunotoxins; Ligation; Male; N-Glycosyl Hydrolases; Neuralgia; Norepinephrine; Pain Threshold; Physical Stimulation; Plant Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Cord; Spinal Nerves; Theobromine; Xanthines

2002
Herpes zoster: adenosine monophosphate for the prevention of post-neuralgia.
    JAMA, 1985, Aug-16, Volume: 254, Issue:7

    Topics: Adenosine; Adenosine Monophosphate; Herpes Zoster; Humans; Neuralgia

1985