Page last updated: 2024-08-24

adenosine and Neoplasm Metastasis

adenosine has been researched along with Neoplasm Metastasis in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19905 (9.80)18.7374
1990's0 (0.00)18.2507
2000's5 (9.80)29.6817
2010's24 (47.06)24.3611
2020's17 (33.33)2.80

Authors

AuthorsStudies
Alispahic, B; Åqvist, J; Azuaje, J; Brea, J; Caamaño, O; Crespo, A; El Maatougui, A; Fernandez-Masaguer, C; Freire-Garabal, M; García-Mera, X; Garcia-Santiago, C; Gioé, C; Gutiérrez-de-Terán, H; Jespers, W; Loza, MI; Majellaro, M; Mallo-Abreu, A; Novio, S; Núñez, MJ; Prieto-Díaz, R; Rodríguez-García, C; Sardina, JF; Sotelo, E; Stefanachi, A1
Li, S; Liang, X; Lv, S; Ren, L; Wang, L; Xu, J; Zhang, S; Zhang, Z1
Fang, X; Liu, LX; Liu, Y; Shi, B; Sun, CL; Wang, H; Wang, JB; Wei, W; Zhang, HS; Zhang, ZY; Zhong, W1
Chen, F; Li, F; Li, YQ; Li, ZX; Lin, L; Liu, N; Lv, JW; Ma, J; Sun, Y; Wu, CF; Yang, PY; Zhang, LL; Zheng, ZQ; Zhou, GQ1
Chen, N; Han, J; He, J; Liao, W; Liu, Z; Yang, J1
Cheng, X; Cui, R; Song, C; Yang, L; Yue, B; Zhang, Z; Zhao, G1
Chen, X; Hao, X; Huang, J; Lan, T; Li, H; Li, J; Liao, H; Liao, M; Liu, H; Wu, H; Xie, K; Xu, L; Yan, X; Yuan, K; Zeng, Y; Zhang, D1
Cheng, C; Jin, J; Li, L; Liu, T; Liu, Y; Luo, Q; Pi, J; Rao, S; Si, Y; Wang, F; Wei, Q; Xiao, H; Yang, Y; Yi, P; Yu, J; Zou, D1
He, X; Hou, B; Huang, K; Huang, S; Ji, F; Ma, Z; Ruan, S; Zhang, C; Zhou, Z; Zhuang, H1
Chen, C; Geng, W; Guo, H; Wang, Q; Wang, S; Wang, Z; Xu, K1
Chen, X; He, B; Li, C; Liu, X; Pan, B; Pan, Y; Qin, J; Sun, H; Sun, L; Wang, S; Xu, M; Xu, T; Xu, X; Zeng, K1
Du, W; Duan, R; Guo, W1
Hao, L; Li, C; Liu, L; Yang, H; Yin, J; Zhong, J; Zhu, L1
Chu, J; He, F; He, J; Jia, J; Sheng, J; Wan, J; Wang, C; Yin, H; Yin, J; Zhou, M1
Ding, X; Li, D; Peng, Y; Wang, X; Wang, Y; Wu, Y; Yang, A; Yang, P; Yin, H; Yu, Y; Zhang, J; Zhang, R; Zhang, X1
Cai, L; Gong, K; Gong, Y; Li, L; Ma, K; Xie, H; Xu, Y; Yang, W; Zhang, K; Zhou, J1
Cook, JL; Corcoran, DL; Degan, S; Erdmann, D; Havran, WL; Healy, E; Jiang, SW; Lai, C; Levinson, H; MacLeod, AS; Reid, C; Robson, SC; Rudolph, R; Spasojevic, I; Suwanpradid, J; Whitley, MJ; Zelac, DE; Zhang, JY1
Fang, R; Shi, H; Ye, L1
Chen, P; Chen, Y; Han, X; Hu, J; Ma, Y; Pan, C; Rao, Q; Wang, X; Xiang, Z; Xu, D1
Avan, A; Bahreyni, A; Behnam-Rassouli, R; Hassanian, SM; Khazaei, M; Parizadeh, MR; Rahmani, F; Ryzhikov, M; Samani, SS1
Anderson, GJ; Cheng, K; Han, X; Lang, J; Li, S; Li, Y; Liu, S; Nie, G; Qi, Y; Qin, H; Sukumar, S; Wang, J; Wei, J; Zhang, Y1
Bar-Eli, M; Brooks, D; Calin, G; Fuentes-Mattei, E; Huang, L; Ivan, C; Jones, SJM; Kim, SJ; Lopez-Berenstein, G; Paret, H; Robertson, AG; Rodriguez-Aguayo, C; Shoshan, E; Sood, A; Velazquez-Torres, G; Xie, V1
Chen, J; Du, B1
Ai, S; Du, S; Feng, M; Guan, W; Miao, J; Shi, L; Song, J; Wu, Z; Xu, E1
Linden, J1
Auchampach, JA; Dwinell, MB; Gonyo, P; Hauser, AD; Kalyanaraman, B; Lorimer, EL; McAllister, D; Ntantie, E; Schuld, N; Williams, CL1
Williams, CL1
Costa, VM; Diniz, C; Fresco, P; Soares, AS2
Antonioli, L; Blandizzi, C; Haskó, G; Pacher, P1
Bar-Eli, M; Birol, I; Braeuer, RR; Brooks, D; Calin, GA; Eterovic, AK; Fidler, IJ; Gershenwald, JE; Huang, L; Hwu, P; Ivan, C; Jones, SJ; Kamiya, T; Kim, SJ; Lee, HJ; Markel, G; Mobley, AK; Mosqueda, M; Nip, KM; Robertson, AG; Salameh, A; Shoshan, E; Sood, AK; Vasquez, ME; Velazquez-Torres, G; Wen, YY; Zhu, K1
Abbott, R; Belikoff, B; Cannici, R; Hatfield, SM; Jackson, EK; Karger, B; Kjaergaard, J; Ko, K; Kutok, JL; Lukashev, D; Ohta, A; Philbrook, P; Podack, ER; Rodig, S; Schreiber, TH; Sethumadhavan, S; Sitkovsky, MV; Thayer, M1
Alexander, MP; Chabanet, TB; Clancy-Thompson, E; Croteau, W; Huang, YH; Mullins, DW; Perekslis, TJ; Turk, MJ1
Cabrera-Fuentes, HA; Cherepanov, V; Kim, MH; Serebruany, VL1
Adinolfi, E; Di Virgilio, F; Falzoni, S; Giuliani, AL1
Liu, F; Ma, JZ; Sun, SH; Wang, F; Wang, TT; Xu, QG; Yang, F; Yuan, JH; Zhou, CC; Zhou, WP1
Battastini, AM; Bavaresco, L; Bernardi, A; Braganhol, E; Cappellari, AR; Delgado-Cañedo, A; Farias, PF; Rockenbach, L; Wink, MR1
Basu, I; Belbin, TJ; Cassera, MB; Dong, X; Evans, GB; Guha, C; Hemeon, I; Locker, J; Merino, EF; Schramm, VL1
Kim, JH; Shin, YJ1
Helenius, M; Jalkanen, S; Yegutkin, G1
Bargonetti, J; Hoffman, S; Krett, NL; Polotskaia, A; Rosen, ST; Shanmugam, M1
Abujamra, AL; Battastini, AM; Braganhol, E; Cappellari, AR; Clarimundo, V; Dietrich, F; Glaser, T; Rockenbach, L; Roesler, R; Ulrich, H1
Ayscue, LH; Jin, A; Lazarowski, E; Mitchell, BS; Ostapkowicz, A; Spychala, J1
Bernini, A; Carlucci, F; Di Pietro, MC; Floccari, F; Leoncini, R; Marinello, E; Rosi, F; Santoro, A; Tabucchi, A; Tanzini, G; Vannoni, D1
Abraham, EH; Cho, SY; Engles, JM; Hilton, J; Polster, J; Wahl, RL1
Phillis, JW; Wu, PH1
Goldman, Y; Peled, A; Shinitzky, M1
Dollinger, MR; Krakoff, IH1
Coombes, RC; Kraus, LE; Rimer, VG; Vold, BS1
Bethune, VG; Fleisher, M; Schwartz, MK1
Lyon, GM1

Reviews

9 review(s) available for adenosine and Neoplasm Metastasis

ArticleYear
Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer.
    Journal of hematology & oncology, 2020, 05-19, Volume: 13, Issue:1

    Topics: Adenosine; Cell Physiological Phenomena; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Glycolipids; Humans; Methylation; Methyltransferases; Models, Biological; Multienzyme Complexes; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplastic Stem Cells; Neovascularization, Pathologic; Protein Biosynthesis; Radiation Tolerance; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Neoplasm

2020
EZH2: a novel target for cancer treatment.
    Journal of hematology & oncology, 2020, 07-28, Volume: 13, Issue:1

    Topics: Adenosine; Antineoplastic Agents; Benzamides; Biphenyl Compounds; Cell Cycle; Cell Transformation, Neoplastic; Clinical Trials as Topic; Combined Modality Therapy; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Histone Code; Histones; Humans; Methylation; Morpholines; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Polycomb Repressive Complex 2; Pyridones; Structure-Activity Relationship; Transcriptional Activation; Tumor Microenvironment

2020
Understanding the roles of N
    Neoplasia (New York, N.Y.), 2021, Volume: 23, Issue:6

    Topics: Adenosine; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Metastasis; RNA, Messenger

2021
Role of adenosine signaling in the pathogenesis of breast cancer.
    Journal of cellular physiology, 2018, Volume: 233, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inflammation; MCF-7 Cells; Neoplasm Metastasis; Receptors, Adenosine A2; Signal Transduction; Tumor Microenvironment

2018
Novel positioning from obesity to cancer: FTO, an m
    Journal of cancer research and clinical oncology, 2019, Volume: 145, Issue:1

    Topics: 3' Untranslated Regions; Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Body Mass Index; Cell Proliferation; Demethylation; Disease Progression; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation; Humans; Neoplasm Metastasis; Neoplasms; Obesity; Oncogenes; Polymorphism, Single Nucleotide; Prognosis; Radiation Tolerance

2019
Immunity, inflammation and cancer: a leading role for adenosine.
    Nature reviews. Cancer, 2013, Volume: 13, Issue:12

    Topics: Adenosine; Animals; Cell Proliferation; Humans; Inflammation; Inflammation Mediators; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neoplasm Metastasis; Neoplasms; Receptors, Purinergic P1; Tumor Microenvironment

2013
Solid cancers after antiplatelet therapy: Confirmations, controversies, and challenges.
    Thrombosis and haemostasis, 2015, Nov-25, Volume: 114, Issue:6

    Topics: Adenosine; Animals; Anticarcinogenic Agents; Aspirin; Blood Platelets; Carcinogenicity Tests; Clopidogrel; Colonic Neoplasms; Drug Therapy, Combination; Female; Humans; Lactones; Male; Mice; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Neoplastic Cells, Circulating; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Randomized Controlled Trials as Topic; Rivaroxaban; Sex Factors; Species Specificity; Ticagrelor; Ticlopidine; Time Factors

2015
P2 receptors in cancer progression and metastatic spreading.
    Current opinion in pharmacology, 2016, Volume: 29

    Topics: Adenosine; Adenosine Triphosphate; Animals; Disease Progression; Humans; Neoplasm Metastasis; Neoplasms; Receptors, Purinergic P2; Tumor Microenvironment

2016
Adenosine may regulate the vascular supply and thus the growth and spread of neoplastic tissues: a proposal.
    General pharmacology, 1981, Volume: 12, Issue:5

    Topics: Adenosine; Animals; Dipyridamole; Humans; Neoplasm Metastasis; Neoplasms

1981

Other Studies

42 other study(ies) available for adenosine and Neoplasm Metastasis

ArticleYear
3,4-Dihydropyrimidin-2(1
    Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1

    Topics: Adenosine A2 Receptor Antagonists; Animals; CHO Cells; Cricetulus; Cyclic AMP; HEK293 Cells; HeLa Cells; Humans; Models, Molecular; Neoplasm Metastasis; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2B; Stereoisomerism; Structure-Activity Relationship

2021
Mechanism of methyltransferase like 3 in epithelial-mesenchymal transition process, invasion, and metastasis in esophageal cancer.
    Bioengineered, 2021, Volume: 12, Issue:2

    Topics: Adenosine; Animals; Base Sequence; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Down-Regulation; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methyltransferases; Mice, Nude; MicroRNAs; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; NFI Transcription Factors; Transcription, Genetic; Up-Regulation

2021
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.
    Cell death & disease, 2021, 12-17, Volume: 13, Issue:1

    Topics: Adenosine; Animals; Humans; Intracellular Signaling Peptides and Proteins; Male; Methyltransferases; Mice; Mice, Nude; Neoplasm Metastasis; Prognosis; Transcription Factor 4

2021
WTAP-mediated m
    Cell death and differentiation, 2022, Volume: 29, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Carcinogenesis; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cytoskeletal Proteins; Epigenesis, Genetic; Formins; Humans; LIM Domain Proteins; Membrane Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; RNA Splicing Factors; RNA-Binding Proteins; RNA, Long Noncoding

2022
m6A Regulators Mediated Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization In Nasopharyngeal Carcinoma.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adenosine; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; RNA, Neoplasm; Tumor Microenvironment; Wnt Signaling Pathway

2021
METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer.
    Molecular cancer, 2019, 10-13, Volume: 18, Issue:1

    Topics: Adenosine; Animals; Biomarkers, Tumor; Cell Line, Tumor; Disease Models, Animal; ELAV-Like Protein 1; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Methyltransferases; Mice; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Proportional Hazards Models; Protein Binding; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Transcriptome

2019
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3.
    Molecular cancer, 2019, 12-19, Volume: 18, Issue:1

    Topics: Adenosine; Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; GATA3 Transcription Factor; Humans; Liver Neoplasms; Methylation; Mice; Models, Biological; Neoplasm Metastasis; Prognosis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Antisense; RNA, Long Noncoding; Xenograft Model Antitumor Assays

2019
The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation.
    Nucleic acids research, 2020, 04-17, Volume: 48, Issue:7

    Topics: Adenosine; Animals; Carcinogenesis; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Eukaryotic Initiation Factor-3; Female; Gene Expression Regulation, Neoplastic; Humans; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogenes; Ovarian Neoplasms; Protein Biosynthesis; RNA-Binding Proteins; RNA, Messenger

2020
YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation.
    Oncogene, 2020, Volume: 39, Issue:23

    Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Octamer Transcription Factor-3; Prognosis; RNA-Binding Proteins; RNA, Messenger; Spheroids, Cellular; Transplantation, Heterologous; Tumor Cells, Cultured

2020
METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer.
    Molecular cancer, 2020, 06-17, Volume: 19, Issue:1

    Topics: Adenosine; Animals; Apoptosis; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Prognosis; SOXC Transcription Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
ALKBH5-mediated m
    Aging, 2021, 01-10, Volume: 13, Issue:3

    Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Demethylation; Disease Progression; Epithelial-Mesenchymal Transition; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Messenger; Uveal Neoplasms

2021
METTL3 restrains papillary thyroid cancer progression via m
    Molecular therapy : the journal of the American Society of Gene Therapy, 2021, 05-05, Volume: 29, Issue:5

    Topics: Adenosine; Animals; Disease Progression; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Male; Methyltransferases; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neutrophil Infiltration; Prognosis; Proto-Oncogene Proteins c-rel; Sequence Analysis, RNA; Thyroid Cancer, Papillary; Thyroid Neoplasms

2021
RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming.
    Nature communications, 2021, 03-02, Volume: 12, Issue:1

    Topics: Adenosine; Animals; Base Sequence; Cell Line, Tumor; Cell Polarity; Cell Proliferation; Cellular Reprogramming; Cytokines; Gene Deletion; Gene Expression Regulation; Lung Neoplasms; Macrophages; Melanoma, Experimental; Methylation; Methyltransferases; Mice, Knockout; Myeloid Cells; Neoplasm Metastasis; NF-kappa B; Programmed Cell Death 1 Receptor; Repressor Proteins; RNA-Binding Proteins; RNA, Neoplasm; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Tumor Microenvironment

2021
Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1.
    Journal of experimental & clinical cancer research : CR, 2021, Mar-10, Volume: 40, Issue:1

    Topics: Adenosine; Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Disease Models, Animal; DNA Methylation; Down-Regulation; Humans; Kidney Neoplasms; Kruppel-Like Transcription Factors; Mice; Mice, Nude; Middle Aged; Neoplasm Metastasis; RNA, Antisense; RNA, Long Noncoding; RNA, Ribosomal; Transfection

2021
ENTPD1 (CD39) Expression Inhibits UVR-Induced DNA Damage Repair through Purinergic Signaling and Is Associated with Metastasis in Human Cutaneous Squamous Cell Carcinoma.
    The Journal of investigative dermatology, 2021, Volume: 141, Issue:10

    Topics: Adenosine; Apyrase; Carcinoma, Squamous Cell; DNA Damage; DNA Repair; Forkhead Transcription Factors; Humans; Interleukin-27; Memory T Cells; Neoplasm Metastasis; Programmed Cell Death 1 Receptor; Skin Neoplasms; Ultraviolet Rays

2021
Silencing of METTL3 effectively hinders invasion and metastasis of prostate cancer cells.
    Theranostics, 2021, Volume: 11, Issue:16

    Topics: Adenosine; Cell Movement; Cell Proliferation; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Methyltransferases; Neoplasm Invasiveness; Neoplasm Metastasis; Prostate; Prostatic Neoplasms; RNA-Binding Proteins; RNA, Messenger; Ubiquitin-Specific Proteases

2021
Inhibition of platelet function using liposomal nanoparticles blocks tumor metastasis.
    Theranostics, 2017, Volume: 7, Issue:5

    Topics: Adenosine; Animals; Antineoplastic Agents; Blood Platelets; Cell Line, Tumor; Liposomes; Mammary Neoplasms, Experimental; Mice, Inbred BALB C; Nanoparticles; Neoplasm Metastasis; Oligopeptides; Ticagrelor; Treatment Outcome

2017
A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression.
    Nature communications, 2018, 01-31, Volume: 9, Issue:1

    Topics: 3' Untranslated Regions; Adenosine; Animals; Cell Line, Tumor; Cell Proliferation; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Inosine; Melanoma; Mice; Mice, Nude; Microfilament Proteins; MicroRNAs; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogenes; RNA Editing; Skin Neoplasms

2018
Adenosine interaction with adenosine receptor A2a promotes gastric cancer metastasis by enhancing PI3K-AKT-mTOR signaling.
    Molecular biology of the cell, 2019, 09-01, Volume: 30, Issue:19

    Topics: Adenosine; Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Metastasis; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Stomach Neoplasms; TOR Serine-Threonine Kinases; Tumor Microenvironment

2019
Adenosine promotes tumor metastasis.
    Science signaling, 2013, May-28, Volume: 6, Issue:277

    Topics: Adenosine; Cell Adhesion; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; Humans; Models, Biological; Neoplasm Metastasis; Phosphorylation; Prenylation; rap GTP-Binding Proteins; Signal Transduction

2013
An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering.
    Science signaling, 2013, May-28, Volume: 6, Issue:277

    Topics: Adenosine; Amino Acid Sequence; Animals; Cell Adhesion; Cell Movement; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Immunoblotting; Immunoprecipitation; Microscopy, Confocal; Models, Biological; Molecular Sequence Data; Neoplasm Metastasis; Prenylation; rap GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Signal Transduction; Tumor Microenvironment

2013
A new signaling paradigm to control the prenylation and trafficking of small GTPases.
    Cell cycle (Georgetown, Tex.), 2013, Volume: 12, Issue:18

    Topics: Adenosine; Animals; Cell Movement; Humans; Models, Biological; Neoplasm Metastasis; rap GTP-Binding Proteins; Signal Transduction; Tumor Microenvironment

2013
Potentiation of cytotoxicity of paclitaxel in combination with Cl-IB-MECA in human C32 metastatic melanoma cells: A new possible therapeutic strategy for melanoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2013, Volume: 67, Issue:8

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Caspases; Cell Culture Techniques; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Humans; Melanoma; Neoplasm Metastasis; Paclitaxel

2013
The combination of Cl-IB-MECA with paclitaxel: a new anti-metastatic therapeutic strategy for melanoma.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:4

    Topics: Adenosine; Animals; Antineoplastic Agents; Cell Physiological Phenomena; Disease Progression; Drug Screening Assays, Antitumor; Humans; Inosine; Melanoma; Mice; Neoplasm Metastasis; Neoplasm Staging; Neovascularization, Pathologic; Paclitaxel; Receptor, Adenosine A3; Tumor Cells, Cultured

2014
Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis.
    Nature cell biology, 2015, Volume: 17, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Animals; Base Sequence; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Inosine; Luciferases; Melanoma; Mice; Mice, Nude; MicroRNAs; Molecular Sequence Data; mRNA Cleavage and Polyadenylation Factors; Neoplasm Metastasis; Neoplasm Transplantation; RNA Editing; RNA-Binding Proteins; Skin Neoplasms; Transcription Factors

2015
Immunological mechanisms of the antitumor effects of supplemental oxygenation.
    Science translational medicine, 2015, Mar-04, Volume: 7, Issue:277

    Topics: Adenosine; Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Hyperoxia; Hypoxia; Immunosuppression Therapy; Killer Cells, Natural; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms; Oxygen; Remission Induction; Respiration; T-Lymphocytes, Regulatory; Tumor Microenvironment

2015
Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease.
    Cancer immunology research, 2015, Volume: 3, Issue:8

    Topics: Adenosine; Animals; CD8-Positive T-Lymphocytes; Chemokines; Cytokines; Disease Models, Animal; Humans; Ligands; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Melanoma; Melanoma, Experimental; Mice, Knockout; Neoplasm Metastasis; Receptors, CXCR3; Signal Transduction; T-Lymphocytes; Tumor Burden

2015
METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N
    Hepatology (Baltimore, Md.), 2017, Volume: 65, Issue:2

    Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Methyltransferases; Mice; Mice, Inbred BALB C; MicroRNAs; Neoplasm Metastasis; RNA Interference; Sensitivity and Specificity; Signal Transduction; Survival Rate; Tumor Cells, Cultured

2017
The role of ecto-5'-nucleotidase/CD73 in glioma cell line proliferation.
    Molecular and cellular biochemistry, 2008, Volume: 319, Issue:1-2

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Affinity Labels; Animals; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Rats; Thioinosine

2008
Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.
    The Journal of biological chemistry, 2011, Feb-11, Volume: 286, Issue:6

    Topics: Adenine; Adenosine; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Deoxyadenosines; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Purine-Nucleoside Phosphorylase; Pyrrolidines; S-Adenosylmethionine; Thionucleosides; Transplantation, Heterologous; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2011
The role of EZH2 in the regulation of the activity of matrix metalloproteinases in prostate cancer cells.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Adenosine; Blotting, Western; Cell Line, Tumor; Cell Movement; DNA-Binding Proteins; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; Polycomb Repressive Complex 2; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Transcription Factors

2012
Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:10

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Line, Tumor; Chromatography, Thin Layer; Diphosphates; Enzyme Assays; Extracellular Fluid; Fluorometry; Homeostasis; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Inosine; Luminescent Measurements; Lymphocytes; Neoplasm Metastasis; Nucleosides; Nucleotides; Pyrophosphatases

2012
8-Amino-adenosine activates p53-independent cell death of metastatic breast cancers.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:11

    Topics: Adenosine; Antineoplastic Agents; Autophagy; Breast Neoplasms; Caspase Inhibitors; Cell Death; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Doxycycline; Female; Humans; Mutant Proteins; Neoplasm Metastasis; Oligopeptides; Receptors, Estrogen; Signal Transduction; Transcription, Genetic; Tumor Suppressor Protein p53

2012
Characterization of ectonucleotidases in human medulloblastoma cell lines: ecto-5'NT/CD73 in metastasis as potential prognostic factor.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Adenosine Triphosphate; Alkaline Phosphatase; beta Catenin; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cerebellum; Child; Diphosphates; Gene Expression Regulation, Neoplastic; Humans; Medulloblastoma; Neoplasm Metastasis; Organ Specificity; Phosphoric Diester Hydrolases; Prognosis; Pyrophosphatases; Signal Transduction

2012
Role of estrogen receptor in the regulation of ecto-5'-nucleotidase and adenosine in breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jan-15, Volume: 10, Issue:2

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Adenosine Triphosphate; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Disease Progression; Estradiol; Estrogens; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Phorbol Esters; Plasmids; Receptors, Estrogen; RNA, Messenger; Time Factors; Transfection

2004
Metabolism of adenosine in human colorectal tumour.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Adenosine; Aged; Aged, 80 and over; Colon; Colorectal Neoplasms; Cyclic AMP; Female; Humans; Male; Middle Aged; Mucous Membrane; Neoplasm Metastasis; Purines; Tumor Cells, Cultured

2004
In vitro evaluation of adenosine 5'-monophosphate as an imaging agent of tumor metabolism.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Caffeine; Carbon Radioisotopes; Cell Line, Tumor; Female; Humans; Immunophenotyping; In Vitro Techniques; Models, Biological; Neoplasm Metastasis; Neoplasms; Positron-Emission Tomography; Time Factors

2006
Effective elimination of lung metastases induced by tumor cells treated with hydrostatic pressure and N-acetyl-L-cysteine.
    Cancer research, 2000, Jan-15, Volume: 60, Issue:2

    Topics: Acetylcysteine; Adenosine; Animals; CD4 Antigens; CD8 Antigens; Female; Humans; Hydrostatic Pressure; Hypersensitivity, Delayed; Lung; Lung Neoplasms; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Metastasis; Spleen

2000
Hemolysis induced by 6-N-hydroxylaminopurine riboside, an adenosine analogue.
    Clinical pharmacology and therapeutics, 1975, Volume: 17, Issue:1

    Topics: Adenosine; Adult; Bilirubin; Blood Cell Count; Breast Neoplasms; Dipyridamole; Erythrocytes; Female; Hemoglobins; Hemolysis; Humans; Hydroxylamines; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasms; Purines; Rectal Neoplasms; Reticulocytes; Time Factors

1975
Use of a monoclonal antibody to detect elevated levels of a modified nucleoside, N-[9-(beta-D-ribofuranosyl)purin-6-ylcarbamoyl]-L-threonine, in the urine of breast cancer patients.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Adenosine; Animals; Antibodies, Monoclonal; Antibody Specificity; Breast Neoplasms; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Hybridomas; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Radioimmunoassay

1986
Automated method for determination of serum 5'-nucleotidase activity.
    Clinical chemistry, 1972, Volume: 18, Issue:12

    Topics: Adenosine; Alkaline Phosphatase; Aminohydrolases; Autoanalysis; Bone Diseases; Clinical Enzyme Tests; Colorimetry; Creatine Kinase; Evaluation Studies as Topic; Humans; Liver Diseases; Liver Neoplasms; Magnesium; Methods; Neoplasm Metastasis; Nickel; Nucleotidases

1972
S-adenosylmethionine in a neuroblastoma.
    Pediatric research, 1971, Volume: 5, Issue:8

    Topics: Abdominal Neoplasms; Adenosine; Catechol O-Methyltransferase; Catecholamines; Chromatography; Cystathionine; Humans; Indicators and Reagents; Male; Methionine; Methods; Neoplasm Metastasis; Neuroblastoma; Norepinephrine; Orbital Neoplasms; S-Adenosylmethionine; Time Factors; Tritium; Vanilmandelic Acid

1971