adenosine has been researched along with Muscle Relaxation in 218 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 82 (37.61) | 18.7374 |
| 1990's | 101 (46.33) | 18.2507 |
| 2000's | 31 (14.22) | 29.6817 |
| 2010's | 3 (1.38) | 24.3611 |
| 2020's | 1 (0.46) | 2.80 |
| Authors | Studies |
|---|---|
| Boyer, JL; Brizzolara, AL; Burnstock, G; Fischer, B; Harden, TK; Hoyle, CH; Jacobson, KA; Knight, GE; Ziganshin, AU; Zimmet, J | 1 |
| Godinho, RO; Pacini, ESA; Satori, NA | 1 |
| Gravas, S; Michel, MC; Okeke, K | 1 |
| Davies, KP; Fu, S | 1 |
| Gur, S; Irat, AM | 1 |
| Balestra, B; Candura, SM; Cervio, M; Chiocchetti, R; Clavenzani, P; Colucci, M; De Angelis, S; De Giorgio, R; Dellabianca, A; Faniglione, M; Tonini, S | 1 |
| Boegehold, MA; Falck, JR; Mustafa, SJ; Nayeem, MA; Ponnoth, DS; Zeldin, DC | 1 |
| Gok, S; Izanli-Paksoy, A; Vural, K | 1 |
| Abdel-Mageed, AB; Burnstock, G; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Kendirci, M; Sikka, SC | 1 |
| Ansari, HR; Batchelor, TP; Dey, RD; Ledent, C; Mustafa, SJ; Nadeem, A; Ponnoth, DS | 1 |
| Alhaj, M; Bozarov, A; Christofi, FL; Cooke, HJ; Grants, I; Hassanain, HH; Ren, T; Wang, YZ; Wunderlich, J; Yu, JG | 1 |
| Janković, R; Radenković, M; Stojanović, M; Stojiljković, M; Topalović, M | 1 |
| Baños, G; Franco, M; Grimaldo, JI; Martínez, F | 1 |
| Correia-de-Sá, P; Faria, M; Timóteo, MA | 1 |
| Grbović, L; Radenković, M | 1 |
| Ozdem, SS; Sadan, G; Tasatargil, A | 1 |
| Abebe, W; Mozaffari, MS | 1 |
| Bény, JL | 1 |
| Andersson, KE; Werkström, V | 1 |
| Correia-de-Sá, P; Faria, M; Lafuente-de-Carvalho, JM; Magalhães-Cardoso, T | 1 |
| Carneiro, FS; Giachini, FR; Inscho, EW; Leite, R; Tostes, RC; Webb, RC | 1 |
| Bonvissuto, F; Marino, A; Postorino, A; Vetri, T | 1 |
| Deussen, A; Dieterich, P; von Klitzing, C | 1 |
| Furukawa, K; Ishii, N; Kataoka, K; Nagao, K; Tsuru, H | 1 |
| Benko, I; Brugós, L; Cseppento, A; Deák, G; Edes, I; Galajda, Z; Gesztelyi, R; Kovács, P; Roszer, T; Sipka, S; Szentmiklósi, AJ; Szilasi, M; Zsuga, J | 1 |
| Bagcivan, I; Kaya, T; Kilicarslan, H; Sarac, B; Yildirim, MK; Yildirim, S | 1 |
| Karlsson, JA; Persson, CG | 1 |
| Aroskar, VA; Dadkar, NK; Dohadwalla, AN | 1 |
| Paul, SM; Skolnick, P | 1 |
| Colby, J; Fedan, JS; Hogaboom, GK; O'Donnell, JP; Westfall, DP | 1 |
| Downes, H; Taylor, SM | 1 |
| Burnstock, G; Hills, J; Klarskov, P; Meldrum, LA | 1 |
| Christie, J; Satchell, DG | 1 |
| Ghai, G; Mustafa, SJ | 1 |
| Maguire, MH; Satchell, DG | 1 |
| Crema, A; Frigo, GM; Lecchini, S; Manzo, L; Onori, L; Tonini, M | 1 |
| Kulkarni, SK; Mehta, AK | 1 |
| Brown, CM; Collis, MG | 1 |
| Fujiwara, M; Hong, SC; Muramatsu, I; Sakakibara, Y | 1 |
| Hagen, EC; Webb, RC | 1 |
| Satchell, D; Smith, R | 1 |
| Miyazaki, M; Nakajima, M; Nishimura, K; Toda, N | 1 |
| Merrill, GF; Young, MA | 1 |
| Ferrero, JD; Frischknecht, R | 1 |
| Berne, RM; Fenton, RA; Rubio, R | 1 |
| Cauvin, C; Pegram, B | 1 |
| Baer, HP | 1 |
| Abe, M; Furukawa, T; Katsuragi, T | 1 |
| Baird-Lambert, J; Davies, LP; Jamieson, DD | 1 |
| Fedan, JS; Sneddon, P; Westfall, DP | 1 |
| Anderson, D; Bacchus, A; Gamble, G; Scott, J | 1 |
| Berne, RM; Rubio, GR; Winn, HR | 1 |
| Baer, HP; Muller, MJ | 1 |
| Goyal, RK; Rattan, S | 1 |
| Fujiwara, M; Miura, A; Muramatsu, I; Shibata, S | 1 |
| Makujina, SR; Mustafa, SJ | 1 |
| Dohi, Y; Kojima, M; Sato, K; Takase, H | 1 |
| Giese, EC; Gugino, SF; Morin, FC; Russell, JA; Steinhorn, RH; Van Wylen, DG | 1 |
| Burnstock, G; Vials, AJ | 2 |
| Hussain, T; Leigh, JH; Mustafa, SJ | 1 |
| Cseppentö, A; Kovács, P; Nosztray, K; Szabó, JZ; Szentmiklósi, AJ; Ujfalusi, A | 1 |
| Black, JW; Prentice, DJ; Shankley, NP | 1 |
| Abbracchio, MP; Bolego, C; Cattabeni, F; Pinna, C; Puglisi, L | 1 |
| Grider, JR; Makhlouf, GM; McHenry, L; Murthy, KS | 1 |
| Chang, CH; Lin, PJ; Tsai, KT; Yao, PC | 1 |
| Collis, MG; Hourani, SM; Lewis, CD; Long, CJ | 1 |
| Martin, PL; Potts, AA | 1 |
| Alexander, SP; Hill, SJ; Kendall, DA; Losinski, A | 1 |
| Collins, P; Jiang, C | 1 |
| Kokubun, S; Suzuki, H | 1 |
| Arvola, P; Pörsti, I; Vapaatalo, H; Vuorinen, P; Wu, X | 1 |
| Caparrotta, L; Chinellato, A; Fassina, G; Froldi, G; Pandolfo, L; Ragazzi, E | 2 |
| Fukata, Y; Fukushima, H; Jinno, Y; Kaneta, S; Kasai, H; Ogawa, N | 1 |
| Aksoy, MO; Kelsen, SG | 1 |
| Brailoiu, E; Branisteanu, DD; Filipeanu, CM; Petrescu, BC; Serban, DN; Slatineanu, S | 1 |
| Ishii, M; Iwamoto, T; Kogi, K; Takagi, N; Toya, Y; Uchibori, T; Umemura, S | 1 |
| Li, CG; Najbar, A; Rand, MJ | 1 |
| Advenier, C; Brisac, AM; Cortijo, J; Laurent, S; Naline, E; Sarriá, B; Zhang, Y | 1 |
| Abebe, W; Makujina, SR; Mustafa, SJ | 1 |
| Abdel-Rahman, AA; el-Mas, MM; Fahim, M; Mustafa, SJ | 1 |
| Buluran, J; Cartier, R; Dagenais, F; Hollmann, C; Leclerc, Y; Pellerin, M | 1 |
| Hou, HX; Hyman, PE; Snape, WJ; Tomomasa, T; Willenbucher, R | 1 |
| Burnstock, G; Vials, A | 1 |
| Belt, JJ; Fedan, JS; Frazer, DG; Yuan, LX | 1 |
| Sehba, FA; Wiener, HL | 1 |
| Thalody, GP; Wiener, HL | 1 |
| Martin, PL; McKenna, DG; Potts, AA; Sykes, AM | 1 |
| Martin, PL; Olsson, RA; Ueeda, M | 1 |
| Colussi, DJ; Cox, BF; Merkel, LA; Perrone, MH; Rivera, LM; Smits, GJ | 1 |
| Kalsner, S | 1 |
| Baccari, MC; Calamai, F; Staderini, G | 1 |
| Bäumert, HG; Burnstock, G; Hoyle, CH; Lambrecht, G; Mutschler, E; Pfaff, O; Windscheif, U; Ziganshin, AU | 1 |
| Alexander, SP; Losinski, A | 1 |
| Bonnet, PA; Boucard, M; Chapat, JP; Laurent, F; Michel, A | 1 |
| Cabell, JF; Hellermann, A; Price, JM | 1 |
| Chang, CH; Chen, MF; Jeng, LB; Lee, WC; Lin, PJ; Tsai, KT; Yao, PC | 1 |
| Chang, CH; Chu, Y; Lin, PJ; Tsai, KT | 1 |
| Brownhill, VR; Hourani, SM; Nicholls, J | 1 |
| Harden, FA; Harrison, GJ; Headrick, J; Jordan, LR; Willis, RJ | 1 |
| Hourani, SM; Prentice, DJ | 2 |
| Boucard, M; Hadjkaddour, K; Laurent, F; Michel, A | 1 |
| Hourani, SM; Kitchen, I; Peachey, JA | 1 |
| Barclay, JK; Woodley, N | 1 |
| Brownhill, VR; Hourani, SM; Kitchen, I | 1 |
| Breisblatt, WM; Carr, AA; Henches, NL; Houghton, JL; Smith, VE; Strogatz, DS | 1 |
| Broadley, KJ; Maddock, HL | 1 |
| Sarioglu, Y; Utkan, T; Yalman, Y; Yildirim, MK; Yildirim, S | 1 |
| Hall, JM; Hourani, SM; Nettell, JJ; Smith, NC | 1 |
| Fullerton, DA; McIntyre, RC; Meldrum, DR; Sheridan, BC | 1 |
| Gür, S; Karahan, ST | 1 |
| Nguyen, DH | 1 |
| Edvinsson, L; Erlinge, D; Malmsjö, M | 1 |
| Berwanger, CS; Cleanthis, TM; Fuller, BJ; Hafez, HM; Mansfield, AO; Stansby, G | 1 |
| Sarioglu, Y; Utkan, T; Yildirim, S | 1 |
| Göksu, OC; Kaya, T; Sarioglu, Y; Yildirim, K; Yildirim, S | 1 |
| Bartel, S; Hendrischke, T; Karczewski, P; Morano, I; Schrader, J; Wolf, WP | 1 |
| Lash, JM | 1 |
| Cohen, S; Nissenkorn, I; Rubinstein, R; Shalev, M | 1 |
| Bültmann, R; Starke, K; Tuluc, F | 1 |
| Cseppentö, A; Kovács, P; Nagy, E; Szabó, JZ; Szentmiklósi, AJ; Ujfalusi, A | 1 |
| Kurnaz, F; Sarioğlu, Y; Utkan, NZ; Utkan, T; Yildirim, S | 1 |
| Barahona, MV; Bustamante, S; García-Sacristán, A; Hernández, M; Orensanz, LM | 1 |
| Cocks, TM; Kemp, BK | 1 |
| Dankelman, J; Goto, M; Kajiya, F; Merkus, D; Spaan, JA; Vergroesen, I; Vink, H | 1 |
| Gür, S; Oztürk, B | 1 |
| Abebe, W; Arif Hasan, AZ; Mustafa, SJ | 1 |
| Frisbee, JC; Lombard, JH | 1 |
| Kyselá, S; Török, J | 1 |
| Boudier, HA; De Mey, JG; Rahn, KH; Schlatter, E; Steinmetz, M | 1 |
| Chang, CC; Chu, Y; Hung, CM; Jeng, LB; Lee, WC; Lin, PJ; Yu, MC | 1 |
| Erden, F; Gacar, MN; Ozdemirci, S; Ulak, G; Utkan, T; Yildiz, F | 1 |
| Grbović, L; Pesić, S; Prostran, M; Radenković, M | 1 |
| Bültmann, R; Klebroff, W; Starke, K | 1 |
| Buckner, SA; Burns, DJ; Gopalakrishnan, M; Gopalakrishnan, SM; Groebe, DR; Milicic, I; Warrior, U; Whiteaker, KL | 1 |
| Kolassa, N; Kraupp, O; Pittner, H; Turnheim, K | 1 |
| Anderson, RG; Johansson, SR | 1 |
| Rösen, P; Schrör, K | 1 |
| Fain, JN; Malbon, CC | 1 |
| Holzmann, S; Kukovetz, WR; Pöch, G; Wurm, A | 1 |
| Brodin, K; Fredholm, BB; Strandberg, K | 1 |
| Cusack, NJ; Planker, M | 1 |
| Baer, HP; Frew, R | 1 |
| Cook, MA; Hamilton, JT; Okwuasaba, FK | 1 |
| Bär, HP; Frew, R; McKenzie, SG | 1 |
| Baer, HP; Burnstock, G; Frew, R | 1 |
| Laustiola, KE; Manninen, V; Metsä-Ketelä, T; Pörsti, I; Vapaatalo, H; Vuorinen, P | 1 |
| Mustafa, SJ; Ramagopal, MV | 2 |
| Gascho, JA; Gehman, JD; Glick, MR | 1 |
| Maayani, S; Murray, JM; Thalody, GP; Wiener, HL | 1 |
| Bailey, SJ; Hourani, SM | 1 |
| Hourani, SM; Kitchen, I; Nicholls, J | 1 |
| Cushing, DJ; Makujina, SR; Mustafa, SJ; Sabouni, MH | 2 |
| Balwierczak, JL; Field, FP; Krulan, CM; Miller, MJ; Sharif, R; Weiss, GB | 1 |
| Mulè, F; Postorino, A; Serio, R | 1 |
| Cushing, DJ; Hussain, T; Mustafa, SJ; Sabouni, MH | 1 |
| Bailey, SJ; Hourani, SM; Kitchen, I; Nicholls, J | 1 |
| Ishii, N; Lue, TF; Takahashi, Y; Tanagho, EA | 1 |
| Burman, M; Huang, LB; Torphy, TJ; Zhou, HL | 1 |
| Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Advenier, C; Blanc, M; Devillier, P; Gnassounou, JP | 1 |
| Advenier, C; Candenas, ML; Cortes, D; D'Ocón, MP; Naline, E | 1 |
| Andersson, KE; Forman, A; Madsen, G; Tøttrup, A | 1 |
| Brackett, LE; Daly, JW | 1 |
| Brown, GL; Douglas, FL; Kotake, AN; Mustafa, SJ; Sabouni, MH | 1 |
| Brănişteanu, DD; Macovei, CG; Serban, DN | 1 |
| Mustafa, SJ; Ramagopal, MV; Sabouni, MH | 2 |
| Gmiro, VE; Komissarov, IV; Serdiuk, SE | 1 |
| Cseppentó, A; Gajdos, A; Juhász-Nagy, A; Kékesi, V; Szegi, J; Szentmiklósi, AJ | 1 |
| Berne, RM; Headrick, JP | 1 |
| King, AD; Milavec-Krizman, M; Müller-Schweinitzer, E | 1 |
| Hope, W; Rose'Meyer, RB | 1 |
| Finney, MJ; Karlsson, JA; Persson, CG | 1 |
| Abel, PW; Han, C | 1 |
| Kane, KA; Kwan, YW; Wadsworth, RM | 1 |
| Satchell, D | 2 |
| Melcher, A; Sylvén, C | 1 |
| Mustafa, SJ; Nakazawa, M; Ramagopal, MV | 1 |
| Ellis, JL; Farmer, SG | 1 |
| Bose, D; Bruni, JE; Elliott, DA; Ong, BY | 1 |
| Allen, TM; Baer, HP; Cass, CE; Clanachan, AS; Cook, DA; Fathi-Afshar, R; Krueger, CA; Vriend, R | 1 |
| Furukawa, K; Nomoto, T | 1 |
| Collis, MG; Martin, FM; Stoggall, SM | 1 |
| Azuma, H; Ishikawa, M; Mizushima-Kasahara, K; Sekizaki, S | 1 |
| Ikeda, Y; Sakai, K; Shiraki, Y; Tanabe, S | 1 |
| Broadley, KJ; Broome, S; Paton, DM | 1 |
| Baer, HP; Murji, A; Vriend, R | 1 |
| Maggi, CA; Manzini, S; Meli, A | 1 |
| Miyamoto, T; Nishida, Y; Suzuki, S | 3 |
| Baer, HP; Vriend, R | 1 |
| Gudenzi, M; Mustafa, SJ; Nakagawa, Y | 1 |
| Baird-Lambert, J; Davies, LP; Marwood, JF | 1 |
| Adami, R; Borin, E; Dorigo, P; Gaion, RM; Gambarotto, L; Trolese, B | 1 |
| Mustafa, SJ; Nakagawa, Y | 1 |
| Chitwood, RW; Mustafa, SJ; Ramagopal, MV | 1 |
| Canning, BJ; Farmer, SG; Wilkins, DE | 1 |
| Ceroni, G; Dorigo, P; Gaion, RM; Giacometti, A; Maragno, I; Valentini, E | 1 |
| Ghai, G; Hopkins, MF; Zimmerman, MB | 1 |
| Krzanowski, JJ; Polson, JB; Sakamoto, Y; Szentivanyi, A; Urdaneta-Bohorquez, A | 1 |
| Collis, MG; Jacobson, KA; Tomkins, DM | 1 |
| Carlsson, I; Sollevi, A; Wennmalm, A | 1 |
| Angus, JA; White, TD | 1 |
| Deason, RD; Flory, W; O'Malley, NA; Venugopalan, CS | 1 |
| Aburada, M; Hosoya, E; Kato, T; Miyamoto, Y; Noguchi, K; Sakanashi, M; Suekawa, M | 1 |
| Merrill, GF; Tozzi, CA | 1 |
| Miwa, K; Toda, N | 1 |
| Paul, RJ; Rubanyi, GM | 1 |
| Askar, AO; Mustafa, SJ | 1 |
| Baxter, GS; Collis, MG; Palmer, DB | 1 |
| Bradley, AB; Morgan, KG | 1 |
2 review(s) available for adenosine and Muscle Relaxation
| Article | Year |
|---|---|
The mechanism(s) of action of the benzodiazepines.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Caffeine; Carbolines; Cats; Cattle; Diazepam; gamma-Aminobutyric Acid; Humans; Molecular Weight; Muscle Relaxation; Neurotransmitter Agents; Niacinamide; Purines; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures; Sleep Wake Disorders | 1981 |
Regulation of adenylate cyclase by adenosine.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Animals; Binding Sites; Brain; Cyclic AMP; Enzyme Activation; Humans; Insulin; Liver; Models, Chemical; Muscle Relaxation; Structure-Activity Relationship; Xanthines | 1979 |
216 other study(ies) available for adenosine and Muscle Relaxation
| Article | Year |
|---|---|
Identification of potent, selective P2Y-purinoceptor agonists: structure-activity relationships for 2-thioether derivatives of adenosine 5'-triphosphate.
Topics: Adenine Nucleotides; Animals; Aorta; Colon; Enzyme Activation; Erythrocyte Membrane; Guinea Pigs; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth; Rabbits; Receptors, Purinergic P2; Structure-Activity Relationship; Sulfides; Turkeys; Type C Phospholipases; Vas Deferens | 1993 |
Impact of the cAMP efflux and extracellular cAMP-adenosine pathway on airway smooth muscle relaxation induced by formoterol and phosphodiesterase inhibitors.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Bronchodilator Agents; Cyclic AMP; Formoterol Fumarate; Muscle Relaxation; Phosphodiesterase Inhibitors; Rats; Receptors, Adrenergic; Trachea | 2023 |
Do β
Topics: Acetylcholine; Adenosine; Animals; Cholinergic Agents; Humans; Muscle Relaxation; Rats; Receptors, Adrenergic, beta-3; Synaptic Transmission; Urinary Bladder | 2017 |
Opiorphin-dependent upregulation of CD73 (a key enzyme in the adenosine signaling pathway) in corporal smooth muscle cells exposed to hypoxic conditions and in corporal tissue in pre-priapic sickle cell mice.
Topics: 5'-Nucleotidase; Adenosine; Anemia, Sickle Cell; Animals; Cells, Cultured; GPI-Linked Proteins; Hypoxia; Male; Mice; Muscle Relaxation; Muscle, Smooth; Oligopeptides; Priapism; Protein Precursors; Rats; Receptor, Adenosine A2B; RNA, Small Interfering; Salivary Proteins and Peptides; Signal Transduction | 2015 |
L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Blood Glucose; Carbachol; Carnitine; Cholinergic Agonists; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Rats; Urinary Bladder; Urinary Bladder, Overactive | 2008 |
Adenosine A1 and A3 receptor agonists inhibit nonadrenergic, noncholinergic relaxations in the guinea pig isolated trachea.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A3 Receptor Agonists; Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Neurons; Nitric Oxide Synthase Type I; Receptor, Adenosine A1; Receptor, Adenosine A3; Trachea | 2009 |
High-salt diet enhances mouse aortic relaxation through adenosine A2A receptor via CYP epoxygenases.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Aorta, Abdominal; Aorta, Thoracic; Blotting, Western; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Mice; Mice, Inbred C57BL; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Phenethylamines; Receptor, Adenosine A2A; Sodium, Dietary; Vasodilator Agents | 2009 |
Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Benzophenanthridines; Bronchodilator Agents; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; KATP Channels; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ovalbumin; Pinacidil; Protein Kinase C; rhoA GTP-Binding Protein; Trachea | 2009 |
Management of erectile function by penile purinergic p2 receptors in the diabetic rat.
Topics: Adenosine; Adenosine Triphosphate; Animals; Diabetes Mellitus; Disease Models, Animal; Immunohistochemistry; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Penile Erection; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reference Values; Sensitivity and Specificity; Streptozocin; Thionucleosides; Uridine Triphosphate | 2009 |
A2A adenosine receptor deficiency leads to impaired tracheal relaxation via NADPH oxidase pathway in allergic mice.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Asthma; Disease Models, Animal; Female; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; NADPH Oxidases; Phenethylamines; Reactive Oxygen Species; Receptor, Adenosine A2A; Signal Transduction; Trachea | 2009 |
Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.
Topics: Adenosine; Animals; Chlorides; Cimetidine; Colon; Dihydropyridines; Dimaprit; Dose-Response Relationship, Drug; Enteric Nervous System; Gastrointestinal Motility; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Intestinal Secretions; Male; Mecamylamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neural Inhibition; Neurogenic Bowel; Neurokinin-1 Receptor Antagonists; Nicotinic Antagonists; Piperidines; Propane; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Histamine H2; Receptors, Neurokinin-1; Reflex; Theophylline; Xanthines | 2009 |
Combined contribution of endothelial relaxing autacoides in the rat femoral artery response to CPCA: an adenosine A2 receptor agonist.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Autacoids; Femoral Artery; Muscle Relaxation; Rats; Receptors, Adenosine A2 | 2012 |
Adenosine participates in regulation of smooth muscle relaxation in aortas from rats with experimental hypothyroidism.
Topics: Adenosine; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypothyroidism; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Phenylephrine; Rats; Thyroidectomy; Vasoconstrictor Agents; Xanthines | 2002 |
Endogenous adenosine prevents post-tetanic release facilitation mediated by alpha3beta2 nicotinic autoreceptors.
Topics: Acetylcholine; Adenosine; Animals; Autoreceptors; Bungarotoxins; Conotoxins; Dihydro-beta-Erythroidine; Electric Stimulation; Female; Male; Motor Neurons; Muscle Relaxation; Neuromuscular Junction; Nicotinic Antagonists; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Nicotinic; Receptors, Presynaptic; Receptors, Purinergic P1; Theobromine; Tritium; Tubocurarine | 2003 |
Analysis of adenosine vascular effect in isolated rat aorta: possible role of Na+/K+-ATPase.
Topics: Adenosine; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sodium-Potassium-Exchanging ATPase; Vasodilator Agents | 2003 |
The effects of selective phosphodiesterase III and V inhibitors on adrenergic and non-adrenergic, non-cholinergic relaxation responses of guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Electric Stimulation; Guinea Pigs; Histamine; Isoproterenol; Male; Milrinone; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Artery; Purinones; Quinoxalines; Receptors, Adrenergic; Receptors, Cholinergic; Signal Transduction; Tetrodotoxin; Theophylline | 2003 |
Effect of taurine deficiency on adenosine receptor-mediated relaxation of the rat aorta.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; beta-Alanine; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Rats; Rats, Inbred WKY; Receptors, Purinergic P1; Taurine; Triazines; Triazoles; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Characterization of purine receptors in mouse thoracic aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta, Thoracic; Biological Factors; Calcimycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Phenylephrine; Receptors, Purinergic P2; Uridine Triphosphate | 2004 |
ATP- and adenosine-induced relaxation of the smooth muscle of the pig urethra.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Muscle Relaxation; Muscle, Smooth; Swine; Thionucleotides; Urethra | 2005 |
Corpus cavernosum from men with vasculogenic impotence is partially resistant to adenosine relaxation due to endothelial A(2B) receptor dysfunction.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Impotence, Vasculogenic; In Vitro Techniques; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Penis; Phenethylamines; Receptor, Adenosine A2B | 2006 |
Determination of adenosine effects and adenosine receptors in murine corpus cavernosum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Atropine; Bretylium Tosylate; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Penile Erection; Phenylephrine; Prazosin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Triazoles | 2007 |
Nitrergic and purinergic interplay in inhibitory transmission in rat gastric fundus.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apamin; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Fundus; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Rats; Rats, Wistar; Receptors, Purinergic; Tetrodotoxin | 2007 |
Relative importance of mechanisms needs clarification.
Topics: Adenosine; Adenosine Diphosphate; Animals; Models, Cardiovascular; Muscle Relaxation; Myocardial Contraction; Receptor, Adenosine A2A; Receptors, Purinergic P2; Swine; Thionucleotides | 2007 |
The participation of adenosine receptors in the adenosine 5'-triphosphate-induced relaxation in the isolated rabbit corpus cavernosum penis.
Topics: Acetamides; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Animals; Caffeine; Flavins; Male; Muscle Relaxation; Muscle, Smooth; Penile Erection; Penis; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Purines; Rabbits; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Receptors, Purinergic P2 | 2007 |
Modulation of adenosine-induced responses in the guinea-pig trachea during long-term caffeine treatment: possible role of epithelium.
Topics: Adenosine; Animals; Body Weight; Caffeine; Capsaicin; Cromolyn Sodium; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Nitroarginine; Trachea | 2007 |
Effect of hypothyroidism on the purinergic responses of corpus cavernosal smooth muscle in rabbits.
Topics: Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Cyclic GMP; Disease Models, Animal; Electric Stimulation; Female; Hypothyroidism; Impotence, Vasculogenic; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Penis; Receptors, Purinergic; Testosterone; Thyroid Hormones; Thyroidectomy | 2008 |
Neither vasoactive intestinal peptide (VIP) nor purine derivatives may mediate non-adrenergic tracheal inhibition.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Atropine; Carbachol; Electric Stimulation; Female; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; Purines; Synaptic Transmission; Theophylline; Trachea; Vasoactive Intestinal Peptide | 1984 |
Peripheral vascular smooth muscle relaxation in normotensive and hypertensive rats.
Topics: Adenosine; Animals; Desoxycorticosterone; Hypertension; Isoproterenol; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Papaverine; Rats; Time Factors | 1980 |
Direct evidence against a role of ATP as the nonadrenergic, noncholinergic inhibitory neurotransmitter in guinea pig tenia coli.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Atropine; Colon; Electric Stimulation; Guanethidine; Guinea Pigs; Histamine; Muscle Relaxation; Neurotransmitter Agents | 1982 |
Distinctive pharmacological profile of a nonadrenergic inhibitory system in bullfrog lung.
Topics: Adenosine; Adenosine Triphosphate; Animals; Atropine; Catecholamines; Dipyridamole; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Lung; Muscle Relaxation; Norepinephrine; Quinidine; Rana catesbeiana; Serotonin; Tetrodotoxin; Vasoactive Intestinal Peptide | 1983 |
A novel non-adrenergic, non-cholinergic nerve-mediated relaxation of the pig bladder neck: an examination of possible neurotransmitter candidates.
Topics: Adenosine; Adenosine Triphosphate; Animals; Electric Stimulation; Female; In Vitro Techniques; Muscle Relaxation; Neurotransmitter Agents; Serotonin; Swine; Urinary Bladder; Vasoactive Intestinal Peptide | 1984 |
Purine receptors in the trachea: is there a receptor for ATP?
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Dose-Response Relationship, Drug; Female; Guinea Pigs; Male; Muscle Relaxation; Purines; Receptors, Cell Surface; Receptors, Drug; Receptors, Purinergic; Trachea | 1980 |
Demonstration of a putative adenosine receptor in rabbit aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta, Thoracic; Dipyridamole; Kinetics; Microsomes; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Subcellular Fractions; Thioinosine | 1982 |
Evidence for separate receptors for ATP and adenosine in the guinea-pig taenia coli.
Topics: Adenosine; Animals; Colon; Dipyridamole; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Receptors, Cell Surface; Receptors, Purinergic | 1982 |
Purine receptors in the guinea-pig internal anal sphincter.
Topics: Adenosine; Adenosine Triphosphate; Anal Canal; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Triazines | 1983 |
Evidence for the presence of P1- and P2-purinoceptors in rat caecum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Caffeine; Cecum; Cyclic AMP; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Quinidine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1983 |
Adenosine relaxes the aorta by interacting with an A2 receptor and an intracellular site.
Topics: Adenosine; Animals; Aorta; Dipyridamole; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Receptors, Cell Surface; Receptors, Purinergic; Sodium Nitrite; Theophylline | 1983 |
Effects of cinepazide on the purinergic responses in the dog cerebral artery.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cerebral Arteries; Cyclic AMP; Dogs; Drug Interactions; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Piperazines | 1984 |
Coronary artery reactivity in deoxycorticosterone acetate hypertensive rats.
Topics: Acetylcholine; Adenosine; Animals; Arteries; Coronary Vessels; Desoxycorticosterone; Epoprostenol; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Adenosine causes contractions in spiral strips and relaxations in transverse strips of guinea-pig trachea: studies on mechanism of action.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Theophylline; Trachea | 1984 |
Responses of isolated dog arteries to amrinone.
Topics: Adenosine; Aminopyridines; Amrinone; Animals; Arteries; Calcium; Cardiotonic Agents; Dinoprost; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Prostaglandins F | 1984 |
Comparative effects of adenosine and nifedipine in rabbit vascular smooth muscle.
Topics: Adenosine; Animals; Calcium; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Rabbits | 1983 |
Calcium movements and the mechanism of the relaxation induced by adenosine in the guinea-pig taenia coli.
Topics: Adenosine; Adenosine Triphosphate; Animals; Biological Transport, Active; Calcium; Colon; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Potassium | 1984 |
Adenosine and the acid-base state of vascular smooth muscle.
Topics: Acid-Base Equilibrium; Adenosine; Animals; Carbon Dioxide; Hydrogen-Ion Concentration; Intracellular Fluid; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Partial Pressure; Swine | 1981 |
Decreased relaxation of isolated mesenteric resistance vessels from 2-kidney, 1 clip Goldblatt hypertensive rats.
Topics: Acetylcholine; Adenosine; Animals; Benzazepines; Blood Pressure; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Vascular Resistance | 1983 |
Effects of adenosine transport inhibitors on adenosine- and nerve-mediated relaxations of guinea pig taenia caeci.
Topics: Adenosine; Animals; Biological Transport; Cecum; Drug Synergism; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neural Inhibition | 1983 |
Discrimination by dipyridamole of two types of responses to adenosine and ATP of the carbachol-induced contraction of guinea-pig trachea.
Topics: Adenosine; Adenosine Triphosphate; Animals; Carbachol; Dipyridamole; Female; Glucose; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea | 1983 |
Potentiation of pharmacological responses to adenosine, in vitro and in vivo.
Topics: Adenosine; Adenylyl Cyclases; Animals; Body Temperature; Brain; Dipyridamole; Drug Synergism; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle Relaxation; Nicotine | 1982 |
Investigation of relaxations of the rabbit anococcygeus muscle by nerve stimulation and ATP using the ATP antagonist ANAPP3.
Topics: Adenosine; Adenosine Triphosphate; Animals; Azides; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Rabbits | 1982 |
Role of the myogenic response in exercise hyperemia.
Topics: Acetylcholine; Adenosine; Animals; Blood Flow Velocity; Dogs; Homeostasis; Hyperemia; Muscle Contraction; Muscle Relaxation; Muscles; Perfusion; Physical Exertion; Vascular Resistance; Vasodilation | 1981 |
The role of adenosine in the regulation of cerebral blood flow.
Topics: Adenosine; Animals; Brain Ischemia; Cats; Cerebrovascular Circulation; Dogs; Hypotension; Hypoxia; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Rabbits; Seizures | 1981 |
Apamin, a nonspecific antagonist of smooth muscle relaxants.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apamin; Atropine; Bee Venoms; Cecum; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Parasympatholytics | 1980 |
Evidence against purinergic inhibitory nerves in the vagal pathway to the opossum lower esophageal sphincter.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Electric Stimulation; Electrophysiology; Esophagogastric Junction; Female; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Neural Inhibition; Opossums; Rest; Tetrodotoxin; Vagus Nerve | 1980 |
Reactivity of isolated canine cerebral arteries to adenine nucleotides and adenosine.
Topics: Adenine Nucleotides; Adenosine; Animals; Cerebral Arteries; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Theophylline | 1980 |
Adenosine-5'-uronamides rapidly desensitize the adenosine A2 receptor in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Coronary Vessels; Cyclohexanes; Humans; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Receptors, Purinergic P1; Structure-Activity Relationship; Swine; Tachyphylaxis | 1993 |
Changes in the endothelial cyclooxygenase pathway in resistance arteries of spontaneously hypertensive rats.
Topics: Acetylcholine; Adenosine; Animals; Endothelium, Vascular; Hypertension; In Vitro Techniques; Male; Meclofenamic Acid; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1994 |
Endothelium-dependent relaxations to adenosine in juvenile rabbit pulmonary arteries and veins.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Pulmonary Artery; Pulmonary Veins; Rabbits | 1994 |
Differential effects of ATP- and 2-methylthioATP-induced relaxation in guinea pig coronary vasculature.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Coronary Vessels; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Purinergic Antagonists; Theophylline; Thionucleotides | 1994 |
Regulation of adenosine receptor function by theophylline in rat aorta.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Animals; Aorta; Colforsin; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norbornanes; Rats; Receptors, Purinergic P1; Theophylline | 1994 |
Adenosine receptors mediate both contractile and relaxant effects of adenosine in main pulmonary artery of guinea pigs.
Topics: Adenosine; Amino Acid Oxidoreductases; Animals; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Nitric Oxide Synthase; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Purines; Receptors, Purinergic P1 | 1995 |
Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cecum; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Heart Atria; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Xanthines | 1995 |
The biphasic response of rat vesical smooth muscle to ATP.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Guanosine Triphosphate; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thioinosine; Uridine Triphosphate; Urinary Bladder; Vasodilator Agents | 1995 |
Adenosine A1 and A2b receptors coupled to distinct interactive signaling pathways in intestinal muscle cells.
Topics: Adenosine; Animals; Guinea Pigs; In Vitro Techniques; Intestine, Small; Muscle Relaxation; Muscle, Smooth; Receptors, Purinergic P1; Signal Transduction | 1995 |
Endothelium-dependent contraction of canine coronary artery is enhanced after 24 hours of preservation with University of Wisconsin solution.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Glutathione; Hypoxia; In Vitro Techniques; Insulin; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Organ Preservation; Organ Preservation Solutions; Potassium; Raffinose | 1995 |
Characterization of adenosine receptors in the rat isolated aorta.
Topics: Adenosine; Animals; Aorta, Thoracic; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1994 |
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Theophylline; Vasodilator Agents; Xanthines | 1994 |
A comparison of A2 adenosine receptor-induced cyclic AMP generation in cerebral cortex and relaxation of pre-contracted aorta.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Cerebral Cortex; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1994 |
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Rabbits; Tetrodotoxin; Theophylline | 1994 |
Subtypes of purinoceptors in rat and dog urinary bladder smooth muscles.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Triazines; Urinary Bladder | 1994 |
Effects of P1 and P2Y purinoceptor antagonists on endothelium-dependent and -independent relaxations of rat mesenteric artery to GTP and guanosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Guanosine; Guanosine Triphosphate; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Triazines | 1994 |
Purine- and nucleotide-mediated relaxation of rabbit thoracic aorta: common and different sites of action.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nucleotides; Purines; Rabbits; Suramin; Uridine Triphosphate; Vasodilator Agents | 1994 |
Comparison of the effects of KRN2391 and other coronary dilators on porcine isolated coronary arteries of different sizes.
Topics: Adenosine; Animals; Benzopyrans; Coronary Vessels; Cromakalim; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channels; Pyridines; Pyrroles; Swine; Vasodilator Agents | 1993 |
Relaxation of rabbit tracheal smooth muscle by adenine nucleotides: mediation by P2-purinoceptors.
Topics: Adenine Nucleotides; Adenosine; Animals; Cyclooxygenase Inhibitors; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Rabbits; Receptors, Purinergic; Trachea | 1994 |
Effects of liposome-entrapped adenosine in the isolated rat aorta.
Topics: Adenosine; Adenosine Deaminase; Animals; Aorta; Calcium Channels; Drug Carriers; In Vitro Techniques; Liposomes; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Protein Kinase C; Rats | 1993 |
Identification of adenosine A2 receptor-cAMP system in human aortic endothelial cells.
Topics: Acetylcholine; Adenosine; Alkynes; Animals; Antihypertensive Agents; Aorta; Aorta, Thoracic; Base Sequence; Cells, Cultured; Cyclic AMP; DNA Primers; Endothelium, Vascular; Humans; In Vitro Techniques; Kinetics; Male; Molecular Sequence Data; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline | 1994 |
The effect of suramin on vasodilator responses to ATP and 2-methylthio-ATP in the Sprague-Dawley rat coronary vasculature.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Vessels; Drug Interactions; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Perfusion; Rats; Rats, Sprague-Dawley; Suramin; Theophylline; Thionucleotides; Vasodilation; Vasodilator Agents | 1994 |
Pharmacological actions of the coenzymes NAD(H) and NADP(H) on the rat anococcygeus muscle.
Topics: Adenosine; Animals; Arginine; Electric Stimulation; Male; Muscle Contraction; Muscle Relaxation; NAD; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Theophylline | 1994 |
The nicardipine-isoprenaline interaction in human and guinea-pig isolated airways.
Topics: Adenosine; Animals; Bronchi; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Humans; Isoproterenol; Male; Muscle Relaxation; Nicardipine; Nifedipine; Nitroprusside; Theophylline; Trachea | 1994 |
Adenosine receptor-mediated relaxation of porcine coronary artery in presence and absence of endothelium.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Kinetics; Muscle Relaxation; Phenethylamines; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Structure-Activity Relationship; Swine | 1994 |
Influence of aortic baroreceptor denervation on adenosine receptor-mediated relaxation of isolated rat aorta.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Arginine; Blood Pressure; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; Muscle Denervation; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1994 |
1993: Effects of University of Wisconsin solution on endothelium-dependent coronary artery relaxation in the rat. Updated in 1994.
Topics: Adenosine; Allopurinol; Animals; Coronary Vessels; Glutathione; Insulin; Muscle Relaxation; Muscle, Smooth, Vascular; Organ Preservation Solutions; Raffinose; Rats; Rheology; Vascular Resistance; Viscosity | 1994 |
Postnatal changes in receptor-mediated rabbit gastric smooth muscle relaxation.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Rabbits; Receptors, Adrenergic; Stomach; Vasoactive Intestinal Peptide; Weaning | 1993 |
A2-purinoceptor-mediated relaxation in the guinea-pig coronary vasculature: a role for nitric oxide.
Topics: Adenosine; Animals; Antihypertensive Agents; Arginine; Coronary Vessels; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenethylamines; Prostaglandins; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines | 1993 |
Relaxant effects of nucleotides in guinea pig isolated, perfused trachea: lack of involvement of prostanoids, Cl- channels and adenosine.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Adenosine Triphosphate; Animals; Chloride Channels; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Membrane Proteins; Mucous Membrane; Muscle Relaxation; Muscle, Smooth; Nucleotides; Prostaglandins; Theophylline; Trachea; Uridine Triphosphate | 1993 |
Kinetics of relaxation responses to vasorelaxants in intact and adventitia- and endothelium-denuded isolated rabbit thoracic aorta.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Kinetics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Rabbits; Vasodilator Agents | 1993 |
Kinetic characterization of adenosine A2 receptor-mediated relaxation in isolated rabbit aorta.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Phenylisopropyladenosine; Rabbits; Receptors, Purinergic P1; Vasodilator Agents | 1993 |
(+-)-N6-endonorbornan-2-yl-9-methyladenine (N-0861) and its enantiomers: selective antagonists of A1-adenosine receptors in guinea pig isolated atria.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Drug Antagonism; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Muscle Relaxation; Norbornanes; Purinergic Antagonists; Stereoisomerism; Vasodilator Agents | 1993 |
2-Phenylethoxy-9-methyladenine: an adenosine receptor antagonist that discriminates between A2 adenosine receptors in the aorta and the coronary vessels from the guinea pig.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Coronary Vessels; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Purinergic Antagonists; Vasodilator Agents | 1993 |
In vitro and in vivo characterization of an A1-selective adenosine agonist, RG14202.
Topics: Adenosine; Animals; Binding Sites; Carotid Arteries; Coronary Vessels; Cyclopentanes; Dinoprost; Dogs; Glyburide; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Swine | 1993 |
Hypoxic relaxation in functionally intact cattle coronary artery segments involves K+ ATP channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arteries; Calcium; Calcium Channel Blockers; Cattle; Coronary Vessels; Glyburide; Guanidines; Hypoxia; In Vitro Techniques; Indomethacin; Muscle Relaxation; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rabbits; Tetrodotoxin; Vasodilator Agents | 1995 |
Prostaglandin E2 modulates neurally induced nonadrenergic, noncholinergic gastric relaxations in the rabbit in vivo.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dinoprostone; Electric Stimulation; Male; Muscle Relaxation; Rabbits; Stomach; Thionucleotides; Vagus Nerve | 1996 |
Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea-pig taenia coli and rat duodenum.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Carbachol; Colon; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Guinea Pigs; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Thionucleotides | 1995 |
Adenosine receptor-mediated relaxation of guinea-pig precontracted, isolated trachea.
Topics: Adenosine; Animals; Aorta; Carbachol; Central Nervous System; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Trachea; Vasodilator Agents | 1995 |
Pharmacological activities of imidazo[1,2-alpha]pyrazine derivatives.
Topics: Adenosine; Animals; Calcium; Cardiovascular Agents; Cattle; Diuresis; Guinea Pigs; Heart Atria; Heart Rate; Ileum; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Phosphodiesterase Inhibitors; Pyrazines; Rabbits; Rats; Rats, Wistar; Theophylline; Trachea | 1995 |
Inhibition of cAMP mediated relaxation in rat coronary vessels by block of Ca++ activated K+ channels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Calcium; Coronary Vessels; Cyclic AMP; Muscle Relaxation; Nitroprusside; Potassium Channel Blockers; Prostaglandin Endoperoxides, Synthetic; Rats; Thromboxane A2; Vascular Resistance | 1996 |
Impaired endothelial-dependent relaxation by acetylcholine after preservation of the human hepatic artery with UW solution.
Topics: Acetylcholine; Adenosine; Allopurinol; Analysis of Variance; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Hepatic Artery; Humans; Insulin; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Organ Preservation; Organ Preservation Solutions; Raffinose | 1996 |
Endothelium-dependent relaxation of the canine pulmonary artery is preserved after prolonged preservation with University of Wisconsin solution.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Dogs; Endothelium, Vascular; Glutathione; Insulin; Muscle Relaxation; Muscle, Smooth, Vascular; Organ Preservation; Organ Preservation Solutions; Phenylephrine; Pulmonary Artery; Raffinose | 1996 |
Characterization of P1-purinoceptors on rat isolated duodenum longitudinal muscle and muscularis mucosae.
Topics: Adenosine; Animals; Duodenum; Male; Muscle Relaxation; Muscle, Smooth; Rats; Receptors, Purinergic P1; Theophylline; Xanthines | 1996 |
A biphasic response to adenosine in the coronary vasculature of the K(+)-arrested perfused rat heart.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Heart; Heart Arrest, Induced; In Vitro Techniques; Male; Muscle Relaxation; Perfusion; Potassium; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Theophylline; Vasodilator Agents | 1996 |
Activation of multiple sites by adenosine analogues in the rat isolated aorta.
Topics: Adenosine; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Sulfonamides; Theophylline; Triazines; Triazoles; Xanthines | 1996 |
Smooth muscle relaxant activity of A1- and A2-selective adenosine receptor agonists in guinea pig trachea: involvement of potassium channels.
Topics: Adenosine; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Glyburide; Guinea Pigs; Hypoglycemic Agents; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Peptides; Potassium Channels; Receptors, Purinergic P1; Theobromine; Trachea; Verapamil | 1996 |
Differential development of adenosine A1 and A2b receptors in the rat duodenum.
Topics: Adenosine; Animals; Duodenum; Male; Muscle Relaxation; Phenethylamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P1; Tritium; Xanthines | 1996 |
Cultured dog aortic endothelial cells release vasodilatory products in response to acetylcholine and adenosine.
Topics: Acetylcholine; Adenosine; Animals; Aorta, Thoracic; Cells, Cultured; Dogs; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Rabbits; Vasodilation; Vasodilator Agents | 1996 |
Differential ontogeny of adenosine receptors in the longitudinal muscle and muscularis mucosae of the rat isolated duodenum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Duodenum; Intestinal Mucosa; Male; Muscle Development; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 1996 |
Effect of African-American race and hypertensive left ventricular hypertrophy on coronary vascular reactivity and endothelial function.
Topics: Adenosine; Adult; Black People; Cardiovascular Agents; Cohort Studies; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Infusions, Intra-Arterial; Male; Middle Aged; Muscle Relaxation; Prospective Studies; White People | 1997 |
Adenosine analogues relax guinea-pig taenia caeci via an adenosine A2B receptor and a xanthine-resistant site.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cecum; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines | 1997 |
P1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hypoxia; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasodilation | 1996 |
Effects of castration on adrenergic, cholinergic and nonadrenergic, noncholinergic responses of isolated corpus cavernosum from rabbit.
Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Carbachol; Electric Stimulation; Male; Muscle Contraction; Muscle Relaxation; Nitroprusside; Orchiectomy; Parasympathomimetics; Penis; Phenylephrine; Rabbits; Testosterone; Vasodilator Agents | 1997 |
Relaxation of the ovine isolated iris sphincter by adenosine receptor agonists: lack of effect of adenosine A1 and A2 receptor antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Iris; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sheep; Vasodilator Agents | 1997 |
KATP channels contribute to beta- and adenosine receptor-mediated pulmonary vasorelaxation.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Glyburide; In Vitro Techniques; Isoproterenol; KATP Channels; Kinetics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Purinergic P1; Tolbutamide; Vasodilation | 1997 |
Effects of adenosine 5'-triphosphate, adenosine and acetylcholine in urinary bladder and colon muscles from streptozotocin diabetic rats.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Body Weight; Colon; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Organ Size; Rats; Urinary Bladder | 1997 |
Role of adenosine-triphosphate-sensitive potassium channels in the mechanical responses of agonist-stimulated isolated porcine coronary arteries.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Coronary Vessels; Cromakalim; GTP-Binding Proteins; In Vitro Techniques; Iron; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Potassium Channels; Swine; Vasodilator Agents | 1997 |
P2U-receptor mediated endothelium-dependent but nitric oxide-independent vascular relaxation.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Female; Indomethacin; Muscle Relaxation; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Thionucleotides; Uridine Triphosphate | 1998 |
Deuterium oxide-based University of Wisconsin solution improves viability of hypothermically stored vascular tissue.
Topics: Adenosine; Allopurinol; Animals; Blood Vessels; Cold Temperature; Deuterium Oxide; Endothelium, Vascular; Glutathione; Insulin; Muscle Relaxation; Muscle, Smooth, Vascular; Organ Preservation; Organ Preservation Solutions; Phenylephrine; Raffinose; Rats; Vasoconstriction | 1998 |
Impaired contraction and relaxation in the aorta of streptozotocin-diabetic rats.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Carbachol; Diabetes Mellitus, Experimental; Endothelin-1; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Rats; Rats, Wistar; Streptozocin; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Effect of additional testosterone on purinergic responses in isolated rabbit corpus cavernosum strips.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Nitroprusside; Penile Erection; Penis; Potassium Chloride; Rabbits; Receptors, Purinergic; Testosterone; Vasodilator Agents | 1998 |
Phosphorylation of phospholamban correlates with relaxation of coronary artery induced by nitric oxide, adenosine, and prostacyclin in the pig.
Topics: Adenosine; Animals; Arteries; Calcium-Binding Proteins; Coronary Vessels; Epoprostenol; In Vitro Techniques; Muscle Relaxation; Muscle Tonus; Myosin Light Chains; Nitric Oxide; Phosphorylation; Swine | 1998 |
Exercise training enhances adrenergic constriction and dilation in the rat spinotrapezius muscle.
Topics: Adenosine; Animals; Citrate (si)-Synthase; Epinephrine; Hydrogen-Ion Concentration; Male; Muscle Contraction; Muscle Relaxation; Muscle, Skeletal; Muscle, Smooth, Vascular; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Effect of exogenous adenosine and its monophosphate on the contractile response to acetylcholine in the human isolated detrusor muscle strips.
Topics: Acetylcholine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Dipyridamole; Drug Interactions; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Theophylline; Vasodilator Agents | 1998 |
On the suitability of adenosine 3'-phosphate 5'-phosphosulphate as a selective P2Y receptor antagonist in intact tissues.
Topics: Adenosine; Animals; Aorta; Colon; Guinea Pigs; Male; Muscle Contraction; Muscle Relaxation; Phosphoadenosine Phosphosulfate; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2Y1; Vas Deferens; Vasodilation | 1998 |
Sensitization by chronic diazepam treatment of A2A adenosine receptor-mediated relaxation in rat pulmonary artery.
Topics: Adenosine; Animals; Carrier Proteins; Diazepam; Dinucleoside Phosphates; Dipyridamole; Dose-Response Relationship, Drug; Female; Heart; Heart Atria; Muscle Relaxation; Phenethylamines; Pulmonary Artery; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Thioinosine; Triazines; Triazoles; Verapamil | 1999 |
Effects of chronic unilateral internal pudendal arterial occlusion on reactivity of isolated corpus cavernosum strips from rabbits.
Topics: Adenosine; Animals; Arterial Occlusive Diseases; Arteries; Carbachol; Chronic Disease; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitroprusside; Papaverine; Parasympathomimetics; Penis; Phenylephrine; Potassium Chloride; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
A2B adenosine receptors mediate relaxation of the pig intravesical ureter: adenosine modulation of non adrenergic non cholinergic excitatory neurotransmission.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Indomethacin; Male; Muscle Relaxation; Receptors, Purinergic P1; Swine; Synaptic Transmission; Theophylline; Ureter; Xanthines | 1999 |
Adenosine mediates relaxation of human small resistance-like coronary arteries via A2B receptors.
Topics: Adenosine; Aged; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Muscle Relaxation; Nitric Oxide; Nitroarginine; Oxyhemoglobins; Potassium; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2B; Receptors, Purinergic P1; Vascular Resistance; Vasodilator Agents | 1999 |
Prolonged diastolic time fraction protects myocardial perfusion when coronary blood flow is reduced.
Topics: Adenosine; Animals; Blood Pressure; Cardiac Pacing, Artificial; Cardiovascular Agents; Coronary Circulation; Diastole; Dogs; Enzyme Inhibitors; Heart; Muscle Relaxation; Myocardial Ischemia; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perfusion; Time Factors; Vascular Resistance | 1999 |
Altered relaxant responses to adenosine and adenosine 5'-triphosphate in the corpus cavernosum from men and rats with diabetes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Relaxation; Penis; Rats | 2000 |
Antagonism of coronary artery relaxation by adenosine A2A-receptor antagonist ZM241385.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Vasodilator Agents | 2000 |
Reduced renal mass hypertension, but not high salt diet, alters skeletal muscle arteriolar distensibility and myogenic responses.
Topics: Adenosine; Animals; Arterioles; Atmospheric Pressure; Hypertension; Male; Muscle Relaxation; Muscle, Skeletal; Muscle, Smooth, Vascular; Nephrectomy; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 2000 |
Contemporary activation of different endothelial receptors accounts for a reserve mechanism of nitric oxide-mediated relaxation.
Topics: Acetylcholine; Adenosine; Adrenergic alpha-Agonists; Animals; Clonidine; Endothelium, Vascular; Histamine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, Histamine; Receptors, Muscarinic; Receptors, Purinergic; Vasodilator Agents | 2000 |
Diadenosine polyphosphates cause contraction and relaxation in isolated rat resistance arteries.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Endothelium, Vascular; Epigastric Arteries; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Inbred WKY; Receptors, Purinergic P2; Sympathectomy; Vascular Resistance | 2000 |
Nitric oxide donor improved the impaired endothelial-dependent relaxation of canine hepatic artery after preservation with UW solution.
Topics: Acetylcholine; Adenosine; Allopurinol; Animals; Dogs; Endothelium, Vascular; Glutathione; Hepatic Artery; Insulin; Molsidomine; Muscle Relaxation; Nitric Oxide Donors; Norepinephrine; Organ Preservation; Organ Preservation Solutions; Potassium; Raffinose; Vasodilation | 2000 |
Chronic ethanol consumption impairs adrenoceptor- and purinoceptor-mediated relaxations of isolated rat detrusor smooth muscle.
Topics: Adenosine; Alcohol Drinking; Animals; Carbachol; Dose-Response Relationship, Drug; Ethanol; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Papaverine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Purinergic | 2001 |
Characterization of adenosine action in isolated rat renal artery. Possible role of adenosine A(2A) receptors.
Topics: Adenosine; Animals; Caffeine; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Indomethacin; Isotonic Solutions; Male; Models, Animal; Muscle Relaxation; Nitroarginine; Potassium Chloride; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Renal Artery; Tetraethylammonium; Vasodilator Agents; Xanthines | 2000 |
Nucleotide-evoked relaxation of rat vas deferens: possible mechanisms.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Nucleotides; Potassium; Rats; Rats, Wistar; Theophylline; Thionucleotides; Vas Deferens | 2002 |
Functional characterization of adenosine receptors and coupling to ATP-sensitive K+ channels in Guinea pig urinary bladder smooth muscle.
Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Glyburide; Guinea Pigs; In Vitro Techniques; KATP Channels; Male; Membrane Potentials; Muscle Relaxation; Muscle, Smooth; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Urinary Bladder; Vasodilator Agents | 2002 |
Relaxation of coronary artery strips by adenosine and acidosis.
Topics: Acidosis; Adenosine; Animals; Blood Vessels; Calcium; Coronary Vessels; Dogs; Drug Interactions; Hydrogen-Ion Concentration; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth | 1977 |
Effects of isoprenaline on the time course of the cyclic AMP level in rat uterus.
Topics: Adenosine; Animals; Catechols; Corticosterone; Cyclic AMP; Dipyridamole; Female; Guanosine Triphosphate; Isoproterenol; Muscle Relaxation; Myometrium; Puromycin; Rats; Theophylline; Uterus | 1978 |
Prostacyclin (PGI2) decreases the cyclic AMP level in coronary arteries.
Topics: Adenosine; Animals; Blood Vessels; Cattle; Coronary Vessels; Cyclic AMP; Epoprostenol; In Vitro Techniques; Muscle Relaxation; Prostaglandins | 1979 |
Prostacyclin increases cAMP in coronary arteries.
Topics: Adenosine; Animals; Arteries; Cattle; Coronary Vessels; Cyclic AMP; Dose-Response Relationship, Drug; Epoprostenol; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Propranolol; Prostaglandins | 1979 |
On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Cyclic AMP; Cyclic GMP; Drug Interactions; Guinea Pigs; Hydrolysis; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Papaverine; Theophylline; Trachea | 1979 |
Relaxation of isolated taenia coli of guinea-pig by enantiomers of 2-azido analogues of adenosine and adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Colon; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Stereoisomerism | 1979 |
Relaxation of guinea-pig fundic strip by adenosine, adenosine triphosphate and electrical stimulation: lack of antagonism by theophylline or ATP treatment.
Topics: Adenosine; Adenosine Triphosphate; Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Stomach; Theophylline | 1979 |
Relaxations of guinea-pig fundic strip by adenosine, adenine nucleotides and electrical stimulation: antagonsism by theophylline and desensitization to adenosine and its derivatives.
Topics: Adenine Nucleotides; Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Parasympatholytics; Rats; Reserpine; Stomach; Theophylline | 1977 |
Characteristics of the relaxant response of adenosine and its analogs in intestinal smooth muscle.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Rabbits; Sympathetic Nervous System; Time Factors | 1977 |
Effect of dipyridamole and 6-(2-hydroxy-5-nitro)-benzylthioguanosine on low-frequency-stimulated relaxation in the guinea pig taenia coli.
Topics: Adenosine; Animals; Colon; Dipyridamole; Electric Stimulation; Female; Guanosine; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Thionucleosides | 1977 |
Endothelium-dependent and -independent effects of exogenous ATP, adenosine, GTP and guanosine on vascular tone and cyclic nucleotide accumulation of rat mesenteric artery.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanosine; Guanosine Triphosphate; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nitroarginine; Nucleotides; Rats; Rats, Inbred Strains | 1992 |
Analysis of the effects of adenosine in skinned bovine coronary artery.
Topics: Adenosine; Animals; Caffeine; Calcium; Cattle; Coronary Vessels; Dinoprost; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Octoxynol; Polyethylene Glycols; Potassium; Saponins | 1992 |
Adenosine increases total venous capacitance in awake instrumented rats.
Topics: Acetylcholine; Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Arrest; Heart Rate; Hexamethonium; Hexamethonium Compounds; Infusions, Intravenous; Male; Muscle Relaxation; Rats; Rats, Inbred Strains; Veins | 1992 |
Kinetics of relaxation responses to vasorelaxants in isolated rabbit aorta.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Rabbits; Vasodilation; Vasodilator Agents | 1992 |
Pharmacological characterization of a new purinergic receptor site in rabbit aorta.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta, Thoracic; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Receptors, Purinergic; Theophylline; Thionucleotides; Vasodilation | 1992 |
Effects of purines on the longitudinal muscle of the rat colon.
Topics: Adenine Nucleotides; Adenosine; Animals; Colon; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1992 |
Characterization of P1-purinoceptors on rat duodenum and urinary bladder.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Duodenum; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Urinary Bladder; Vasodilator Agents; Xanthines | 1992 |
Inhibition of adenylate cyclase attenuates adenosine receptor-mediated relaxation in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Dideoxyadenosine; Dilazep; Guanosine Triphosphate; In Vitro Techniques; Muscle Relaxation; Receptors, Purinergic; Sodium Fluoride; Swine; Vasodilator Agents | 1991 |
Comparative effects of a selective adenosine A2 receptor agonist, CGS 21680, and nitroprusside in vascular smooth muscle.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-Agonists; Animals; In Vitro Techniques; Kinetics; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenethylamines; Rabbits; Vasodilator Agents | 1991 |
Evidence that adenosine is not involved in the non-adrenergic non-cholinergic relaxation in the rat duodenum.
Topics: Adenosine; Animals; Atropine; Duodenum; Electric Stimulation; Guanethidine; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth; Pressure; Rats; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1990 |
G proteins subserve relaxations mediated by adenosine receptors in human coronary artery.
Topics: Adenosine; Adenosine Diphosphate Ribose; Adult; Autoradiography; Cholera Toxin; Coronary Vessels; Female; GTP-Binding Proteins; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Receptors, Purinergic | 1991 |
Protein kinase C and phospholipase C in adenosine receptor-mediated relaxation in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alkaloids; Animals; Coronary Vessels; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Receptors, Purinergic; Staurosporine; Swine; Type C Phospholipases | 1991 |
Direct effects of adenylyl 5'-(beta,gamma-methylene)diphosphonate, a stable ATP analogue, on relaxant P1-purinoceptors in smooth muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1991 |
Pharmacological effects of adenosine on canine penile erection.
Topics: Acetylcholine; Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Cavernous Sinus; Dipyridamole; Dogs; Drug Interactions; Electric Stimulation; Injections; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Penile Erection; Theophylline | 1991 |
Role of cyclic nucleotide phosphodiesterase isozymes in intact canine trachealis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Cyclic AMP; Dogs; Female; Isoenzymes; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Phosphodiesterase Inhibitors; Trachea | 1991 |
Effects of NZ-107 on tracheal responses to adenosine in the guinea pig.
Topics: Adenosine; Aminophylline; Animals; Asthma; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Pyridazines; Trachea | 1991 |
Peripheral type benzodiazepine receptors and response to adenosine on the guinea-pig isolated trachea.
Topics: Adenosine; Animals; Benzodiazepines; Clonazepam; Diazepam; Dipyridamole; Drug Synergism; GABA-A Receptor Antagonists; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Receptors, GABA-A; Theophylline; Trachea | 1990 |
Effects of cularine and other isoquinoline alkaloids on guinea-pig trachea and human bronchus.
Topics: Adenosine; Alkaloids; Animals; Bronchi; Calcium; Guinea Pigs; Histamine; Humans; In Vitro Techniques; Isoquinolines; Male; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Papaverine; Potassium Chloride; Theophylline; Trachea | 1990 |
The actions of some beta-receptor agonists and xanthines on isolated muscle strips from the human oesophago-gastric junction.
Topics: Adenosine; Adrenergic beta-Agonists; Adult; Aged; Dobutamine; Dose-Response Relationship, Drug; Esophagogastric Junction; Female; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Tetrodotoxin; Xanthines | 1990 |
Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms.
Topics: Adenosine; Animals; Carbachol; Deoxyadenosines; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Receptors, Purinergic; Theophylline; Thionucleosides; Trachea; Xanthine; Xanthines | 1991 |
Effects of CGS-15943A on the relaxations produced by adenosine analogs in human blood vessels.
Topics: Adenosine; Adult; Coronary Vessels; Humans; In Vitro Techniques; Mammary Arteries; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Quinazolines; Saphenous Vein; Theophylline; Triazoles | 1990 |
Adenosine alters the vascular effects of a diacylglycerol analogue and polymyxin B.
Topics: Adenosine; Animals; Aorta, Thoracic; Diglycerides; Endothelium, Vascular; Glycerides; In Vitro Techniques; Motor Endplate; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Polymyxin B; Polymyxins; Potassium Chloride; Rats | 1990 |
Relaxation by adenosine and its analogs of potassium-contracted human coronary arteries.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Coronary Vessels; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Potassium; Receptors, Purinergic | 1990 |
[Adenosinergic neurons in intramural ganglia of the small intestine].
Topics: Adenosine; Adenosine Triphosphate; Animals; Choline; Dipyridamole; Electric Stimulation; Ileum; In Vitro Techniques; Muscle Relaxation; Myenteric Plexus; Neurons; Purinergic Antagonists; Rats; Receptors, Purinergic | 1990 |
Extracellular calcium-dependent and -independent effects of adenosine in bovine coronary artery.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Calcium Radioisotopes; Cattle; Coronary Vessels; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylisopropyladenosine; Potassium Chloride | 1990 |
Concentration-dependent action of 4-aminopyridine on the adenosine-induced sinus slowing and vasorelaxation.
Topics: 4-Aminopyridine; Adenosine; Animals; Calcium Channel Blockers; Dogs; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Sinoatrial Node | 1990 |
Endothelium-dependent and -independent relaxations to adenosine in guinea pig aorta.
Topics: Adenosine; Animals; Aorta, Thoracic; Coronary Disease; Endothelium, Vascular; Guinea Pigs; Hypoxia; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Prostanoic Acids | 1990 |
Characterization of the adenosine receptor in porcine coronary arteries.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Coronary Vessels; Dinoprost; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Receptors, Purinergic; Swine | 1990 |
Evidence that A2 purinoceptors are involved in endothelium-dependent relaxation of the rat thoracic aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
Effects of bronchoconstrictors and bronchodilators on a novel human small airway preparation.
Topics: Adenosine; Adenosine Triphosphate; Bronchi; Bronchodilator Agents; Carbachol; Histamine; Humans; In Vitro Techniques; Lung; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Prostaglandin D2; Prostaglandins D; Substance P; Terbutaline; Theophylline; Xanthines | 1985 |
Effects of neuropeptide Y on contraction, relaxation, and membrane potential of rabbit cerebral arteries.
Topics: Acetylcholine; Adenosine; Animals; Cerebral Arteries; Histamine; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle Denervation; Muscle Relaxation; Muscle, Smooth, Vascular; Neuropeptide Y; Ouabain; Potassium; Rabbits | 1989 |
Responsiveness of sheep isolated coronary artery rings under simulated myocardial ischaemia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Coronary Disease; Coronary Vessels; Epoprostenol; Glucose; Guinea Pigs; Hydrogen-Ion Concentration; Iloprost; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Oxygen; Potassium; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sheep | 1989 |
Use of purine nucleotide and nucleoside metabolising enzymes as tools to determine the presence of purinergic nerve transmission in smooth muscle.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Colon; Dipyridamole; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Nucleoside Deaminases; Pyrophosphatases; Synaptic Transmission; Trachea; Vasoactive Intestinal Peptide | 1989 |
Chest pain and oesophageal pressure relationships in man following an intravenous bolus of adenosine.
Topics: Adenosine; Adult; Chest Pain; Esophagogastric Junction; Esophagus; Humans; Male; Muscle Relaxation; Peristalsis; Pressure; Time Factors | 1989 |
Relaxing effects of adenosine in coronary artery in calcium-free medium.
Topics: Adenosine; Animals; Bradykinin; Calcium; Calcium Radioisotopes; Cattle; Coronary Vessels; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular | 1989 |
The effects of vasoactive intestinal peptide (VIP) antagonists, and VIP and peptide histidine isoleucine antisera on non-adrenergic, non-cholinergic relaxations of tracheal smooth muscle.
Topics: Adenosine; Animals; Antibodies; Atropine; Autonomic Nervous System; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Naloxone; Peptide PHI; Propranolol; Sympathectomy, Chemical; Tetrodotoxin; Trachea; Vasoactive Intestinal Peptide | 1989 |
Role of endothelium in hypoxic contraction of canine basilar artery.
Topics: Adenosine; Animals; Arginine Vasopressin; Basilar Artery; Dogs; Endothelium, Vascular; Female; Hemoglobins; Hydroquinones; Hypoxia; In Vitro Techniques; Isometric Contraction; Male; Microscopy, Electron, Scanning; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride | 1989 |
Some pharmacological activities of novel adenine-related compounds isolated from a marine sponge Agelas mauritiana.
Topics: Adenine; Adenosine; Animals; Aorta; Cell Cycle; Erythrocytes; In Vitro Techniques; Kinetics; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthols; Porifera; Rabbits; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1989 |
Postnatal changes in response to adenosine and adenine nucleotides in rat duodenum.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Duodenum; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1989 |
Apparent affinity of 1,3-dipropyl-8-cyclopentylxanthine for adenosine A1 and A2 receptors in isolated tissues from guinea-pigs.
Topics: Adenosine; Animals; Aorta, Thoracic; Binding, Competitive; Guinea Pigs; Heart Rate; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Receptors, Purinergic; Theophylline; Trachea; Xanthines | 1989 |
Roles of calcium and the endothelium in the relaxations produced by 5'-N-ethylcarboxamidoadenosine (NECA).
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cattle; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Vasodilator Agents | 1989 |
Augmentation of adenosine-induced relaxation response with hydralazine in aortic strips.
Topics: Adenosine; Animals; Aorta; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Hydralazine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits | 1988 |
Enhancement of adenosine-induced relaxant responses of the guinea-pig isolated taenia coli and aortae by a novel nootropic agent BY-1949: comparison with dipyridamole.
Topics: Adenosine; Animals; Aorta, Thoracic; Brain; Colon; Dibenzoxazepines; Dipyridamole; Drug Synergism; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Papaverine | 1988 |
Hypothermia-induced supersensitivity to adenosine for responses mediated via A1-receptors but not A2-receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbachol; Female; Guinea Pigs; Heart; Hypothermia; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Rats; Receptors, Cell Surface; Receptors, Purinergic; Trachea; Vas Deferens | 1985 |
Interaction of 2',3'-di-O-nitro-5'-(N-ethylcarboxamido)adenosine with adenosine receptors in intestinal smooth muscle.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Colon; Coronary Vessels; Female; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Male; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Time Factors | 1985 |
Further evidence for involvement of adenosine-5'-triphosphate in non-adrenergic non-cholinergic relaxation of the isolated rat duodenum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autonomic Nervous System; Chymotrypsin; Duodenum; gamma-Aminobutyric Acid; Male; Muscle Relaxation; Muscle, Smooth; Potassium; Pyrophosphatases; Rats; Rats, Inbred Strains; Theophylline | 1985 |
Pharmacological action of 5'-methylthioadenosine on isolated rabbit aorta strips.
Topics: Adenosine; Animals; Aorta, Thoracic; Deoxyadenosines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Receptors, Cell Surface; Receptors, Purinergic; Thionucleosides | 1985 |
Adenosine receptors in smooth muscle: structure-activity studies and the question of adenylate cyclase involvement in control of relaxation.
Topics: Adenosine; Animals; Arteries; Cattle; Coronary Vessels; Guinea Pigs; Intestines; Jejunum; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Organ Specificity; Rabbits; Rats; Receptors, Cell Surface; Receptors, Purinergic; Ribonucleosides; Structure-Activity Relationship | 1985 |
Calcium entry blocking activity of dilazep in dog coronary artery.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Arteries; Azepines; Calcium; Calcium Channel Blockers; Coronary Vessels; Dilazep; Diltiazem; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Lidoflazine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
Studies on several pyrrolo[2,3-d]pyrimidine analogues of adenosine which lack significant agonist activity at A1 and A2 receptors but have potent pharmacological activity in vivo.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Brain; Cyclic AMP; Guanosine; Guinea Pigs; Heart Rate; Male; Mice; Muscle Relaxation; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Tubercidin | 1986 |
Involvement of P1-purinoreceptors in the relaxing effect of adenosine in rat duodenum.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Duodenum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1988 |
Relaxing effects of dilazep and lidoflazine in dog cerebral and renal arteries independent of adenosine.
Topics: Adenosine; Adenosine Deaminase; Animals; Azepines; Cerebral Arteries; Dilazep; Dinoprost; Dogs; Female; In Vitro Techniques; Isometric Contraction; Lidoflazine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Piperazines; Potassium; Renal Artery; Serotonin | 1988 |
Evidence for an A2 adenosine receptor in human coronary arteries.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Coronary Vessels; Diltiazem; Dinoprost; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Receptors, Purinergic | 1988 |
Adenosine receptor-mediated contraction and relaxation of guinea-pig isolated tracheal smooth muscle: effects of adenosine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dipyridamole; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phenylisopropyladenosine; Receptors, Purinergic; Trachea | 1988 |
The response of isolated guinea-pig aorta to amrinone.
Topics: Adenosine; Adenosine Deaminase; Amrinone; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Quinidine; Theophylline | 1988 |
Evidence for A1 and A2 adenosine receptors in guinea pig trachea.
Topics: Adenosine; Animals; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Muscle Relaxation; Muscle, Smooth; Receptors, Purinergic; Structure-Activity Relationship; Trachea | 1987 |
Effects of adenosine and theophylline on canine tracheal smooth muscle tone.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Dogs; Drug Interactions; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Theophylline; Trachea | 1987 |
Apparent affinity of some 8-phenyl-substituted xanthines at adenosine receptors in guinea-pig aorta and atria.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cell Membrane; Guinea Pigs; Heart; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Receptors, Purinergic; Xanthines | 1987 |
The role of myogenic relaxation, adenosine and prostaglandins in human forearm reactive hyperaemia.
Topics: Adenosine; Adult; Arteries; Constriction; Female; Forearm; Humans; Ibuprofen; Male; Muscle Contraction; Muscle Relaxation; Prostaglandins; Regional Blood Flow; Theophylline; Veins | 1987 |
Relaxant effects of ATP and adenosine on canine large and small coronary arteries in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Triphosphate; Animals; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle Relaxation; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic | 1987 |
Inhibitory effects of selected purine derivatives on guinea pig pulmonary tissues.
Topics: Adenine Nucleotides; Adenosine; Animals; Cricetinae; Dose-Response Relationship, Drug; Female; Histamine; In Vitro Techniques; Isoproterenol; Lung; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Purines; Trachea | 1986 |
Effects of the water extract of Chrysanthemum indicum Linn. on coronary and systemic hemodynamics in the dog.
Topics: Adenosine; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Plant Extracts; Renal Circulation; Time Factors | 1986 |
Differential effects of adenosine and verapamil on histamine vascular contractions.
Topics: Adenosine; Animals; Calcium; Chlorpheniramine; Histamine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Verapamil | 1986 |
Actions of 5'-methylthioadenosine in isolated guinea pig tracheal rings.
Topics: Adenosine; Animals; Deoxyadenosines; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Receptors, Purinergic; SRS-A; Thionucleosides; Trachea | 1986 |
Suppression by 5'-methylthioadenosine of histamine or leukotriene-induced contraction in isolated guinea pig tracheal rings.
Topics: Adenosine; Animals; Deoxyadenosines; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Propranolol; Receptors, Purinergic; SRS-A; Tetrodotoxin; Theophylline; Thionucleosides | 1986 |
Inferences on the rapid metabolism of exogenously applied ATP in isolated smooth muscle preparations using pharmacological studies.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Intestines; Muscle Relaxation; Muscle, Smooth; Trachea | 1986 |
The regional difference of relaxations induced by various vasodilators in isolated dog coronary and mesenteric arteries.
Topics: Adenosine; Alprostadil; Animals; Coronary Vessels; Diltiazem; Dogs; Epoprostenol; Female; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Thromboxane A2; Vasodilator Agents | 1985 |
Alterations of arachidonic acid metabolism modulate adenosine relaxation in isolated coronary arteries.
Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Coronary Vessels; Dogs; Enzyme Inhibitors; Female; Indomethacin; Lipoxygenase; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Swine | 1985 |
Effect of calcium entry blockers and adenosine on the relaxation of large and small coronary arteries.
Topics: Adenosine; Animals; Arteries; Calcium Channel Blockers; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; Gallopamil; Lidoflazine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Theophylline | 1986 |
Evidence that the intracellular effects of adenosine in the guinea-pig aorta are mediated by inosine.
Topics: Adenosine; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Theophylline; Thioinosine | 1986 |
Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation.
Topics: Adenosine; Aequorin; Animals; Body Fluids; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Ferrets; In Vitro Techniques; Intracellular Fluid; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Portal Vein; Potassium; Theophylline | 1985 |