Page last updated: 2024-08-24

adenosine and Lesch-Nyhan Syndrome

adenosine has been researched along with Lesch-Nyhan Syndrome in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (57.69)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (30.77)	29.6817
2010's	3 (11.54)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Puig, JG; Torres, RJ	1
Garcia, MG; Prior, C; Puig, JG; Torres, RJ	1
García, MG; Puig, JG; Torres, RJ	2
Deantonio, I; Prior, C; Puig, JG; Torres, RJ	4
Bertelli, M; Cecchin, S; Jacomelli, G; Jinnah, HA; Lapucci, C; Micheli, V; Pandolfo, M	1
Prior, C; Puig, JG; Torres, RJ	2
Stone, TW	1
Boorstein, R; Campisi, J; Hafner, J; Pardee, AB	1
Burnstock, G	1
Balis, ME	1
Seegmiller, JE; Shreier, MH; Waldmann, TA; Watanabe, T	1
Reem, GH	2
Berlin, RD; O'Connor, N; Oliver, JM; Pritchard, JB	1
Ervin, FR; Heshka, TW; Palmour, RM	1
Breese, GR; Criswell, H; Mueller, RA	1
Holland, MJ; Kelleher, JK; Murphy, E	1
Kelley, WN	1
Pinsky, L; Wood, S	1
Nyhan, WL; Sweetman, L	1

Reviews

6 review(s) available for adenosine and Lesch-Nyhan Syndrome

Article	Year
A review of the implication of hypoxanthine excess in the physiopathology of Lesch-Nyhan disease. Nucleosides, nucleotides & nucleic acids, 2016, Volume: 35, Issue:10-12 Topics: Adenosine; Biological Transport; Cell Differentiation; Homeodomain Proteins; Humans; Hypoxanthine; Lesch-Nyhan Syndrome; Neurons; Wnt4 Protein	2016
Physiological roles for adenosine and adenosine 5'-triphosphate in the nervous system. Neuroscience, 1981, Volume: 6, Issue:4 Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Aging; Animals; Behavior; Biological Transport; Brain; Humans; Lesch-Nyhan Syndrome; Muscular Dystrophies; Nervous System; Nervous System Physiological Phenomena; Neurons; Neurotransmitter Agents; Phosphates	1981
The purinergic nerve hypothesis. Ciba Foundation symposium, 1977, Issue:48 Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Autonomic Nervous System; Chagas Disease; Digestive System Physiological Phenomena; Dipyridamole; Humans; Imidazoles; Lesch-Nyhan Syndrome; Muscle, Smooth; Nerve Endings; Neurotransmitter Agents; Norepinephrine; Nucleotidases; Receptors, Drug; Structure-Activity Relationship; Tissue Distribution	1977
Uric acid metabolism in man. Advances in clinical chemistry, 1976, Volume: 18 Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Animals; Cells, Cultured; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Lymphocytes; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Rats; Ribose-Phosphate Pyrophosphokinase; Sex Chromosomes; Uric Acid; Xanthines	1976
Immunological aspects of purine metabolism. Advances in experimental medicine and biology, 1977, Volume: 76A Topics: Adenine; Adenosine; Adenosine Deaminase; Antibody Formation; Hormones; Humans; Immunity, Cellular; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Inosine; Lesch-Nyhan Syndrome; Liver; Lymphocyte Activation; Lymphocytes; Mercaptopurine; Models, Biological; Nucleoside Deaminases; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purines; Synaptic Transmission; Uridine	1977
Purine biosynthesis in mutant mammalian cells. Ciba Foundation symposium, 1977, Issue:48 Topics: Adenosine; Amidophosphoribosyltransferase; Amino Sugars; Animals; Cells, Cultured; Cricetinae; Dimethyl Sulfoxide; Fibroblasts; Formates; Glutamine; Glycine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Leukemia, Erythroblastic, Acute; Lung; Lymphocytes; Mutation; Phosphoribosyl Pyrophosphate; Purines; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates	1977

Other Studies

20 other study(ies) available for adenosine and Lesch-Nyhan Syndrome

Article	Year
Hypoxanthine deregulates genes involved in early neuronal development. Implications in Lesch-Nyhan disease pathogenesis. Journal of inherited metabolic disease, 2015, Volume: 38, Issue:6 Topics: Adenosine; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Homeodomain Proteins; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Neurons; Receptors, Dopamine D1; Tretinoin; Tyrosine 3-Monooxygenase; Wnt Signaling Pathway; Wnt4 Protein	2015
Abnormal adenosine and dopamine receptor expression in lymphocytes of Lesch-Nyhan patients. Brain, behavior, and immunity, 2009, Volume: 23, Issue:8 Topics: Adenosine; Adolescent; Child; Child, Preschool; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Hypoxanthine; Lesch-Nyhan Syndrome; Lymphocytes; Receptors, Adenosine A2; Receptors, Dopamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Young Adult	2009
Adenosine, dopamine and serotonin receptors imbalance in lymphocytes of Lesch-Nyhan patients. Journal of inherited metabolic disease, 2012, Volume: 35, Issue:6 Topics: Adenosine; Adolescent; Base Sequence; Case-Control Studies; Child; Child, Preschool; Dopamine; Humans; Lesch-Nyhan Syndrome; Lymphocytes; Receptor, Adenosine A2A; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D5; RNA, Messenger; Serotonin; Young Adult	2012
Adenosine transport in peripheral blood lymphocytes from Lesch-Nyhan patients. The Biochemical journal, 2004, Feb-01, Volume: 377, Issue:Pt 3 Topics: Adenosine; Biological Transport; Cells, Cultured; Cyclic AMP; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Lymphocytes; Thioinosine	2004
Effects of hypoxanthine on adenosine transport in human lymphocytes. Implications in the pathogenesis of Lesch-Nyhan syndrome. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Adenosine; Binding Sites; Biological Transport; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Hypoxanthine; Lesch-Nyhan Syndrome; Lymphocytes; Time Factors	2004
Hypoxanthine effects on cyclic AMP levels in human lymphocytes. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Adenosine; Antihypertensive Agents; Cyclic AMP; Enzyme-Linked Immunosorbent Assay; Humans; Hypoxanthine; Lesch-Nyhan Syndrome; Lymphocytes; Phenethylamines; Receptors, Adenosine A2; Receptors, Purinergic P1; Temperature; Time Factors	2004
Adenosine transport in HPRT deficient lymphocytes from Lesch-Nyhan disease patients. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Adenosine; Biological Transport; Dose-Response Relationship, Drug; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Kinetics; Lesch-Nyhan Syndrome; Lymphocytes; Nucleosides; Nucleotides; Time Factors	2004
Study of the adenosinergic system in the brain of HPRT knockout mouse (Lesch-Nyhan disease). Clinica chimica acta; international journal of clinical chemistry, 2006, Volume: 373, Issue:1-2 Topics: Adenosine; Animals; Brain; Disease Models, Animal; Gene Expression Profiling; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Adenosine A1; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2006
Hypoxanthine effect on equilibrative and concentrative adenosine transport in human lymphocytes: implications in the phatogenesis of Lesch-Nyhan syndrome. Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:9-11 Topics: Adenosine; Biological Transport; Case-Control Studies; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Lymphocytes	2006
Hypoxanthine decreases equilibrative type of adenosine transport in lymphocytes from Lesch-Nyhan patients. European journal of clinical investigation, 2007, Volume: 37, Issue:11 Topics: Adenosine; Adolescent; Adult; Child; Child, Preschool; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Lymphocytes; Nucleoside Transport Proteins	2007
Hereditary orotic aciduria, Lesch-Nyhan syndrome, and xeroderma pigmentosum probed by herpes simplex virus: 125I-iododeoxycytidine incorporation as an assay for viral growth. Journal of cellular physiology, 1983, Volume: 114, Issue:1 Topics: Adenosine; Bromodeoxycytidine; Cells, Cultured; Deoxycytidine; DNA, Viral; Herpes Simplex; Humans; Lesch-Nyhan Syndrome; Orotic Acid; Thioguanine; Ultraviolet Rays; Virus Replication; Xeroderma Pigmentosum	1983
Purine and pyrimidine metabolism. Ciba Foundation symposium, 1977, Issue:48 Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Ascorbic Acid; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Methylene Blue; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Ribosemonophosphates; Uric Acid	1977
Adenosine metabolism in permanent lymphocyte lines and in erythrocytes of patients with the Lesch-Nyhan syndrome. Advances in experimental medicine and biology, 1977, Volume: 76A Topics: Adenosine; Cell Line; Child; Erythrocytes; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Lymphocytes; Purine Nucleotides	1977
Uptake and supply of purine compounds by the liver. The American journal of physiology, 1975, Volume: 229, Issue:4 Topics: Adenosine; Animals; Brain; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Liver; Perfusion; Purines; Rabbits; Rats	1975
Hypoxanthine accumulation and dopamine depletion in Lesch-Nyhan disease. Advances in experimental medicine and biology, 1989, Volume: 253A Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apomorphine; Brain; Dopamine; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Rats; Rats, Inbred Strains; Trigeminal Caudal Nucleus	1989
Assessment of purine-dopamine interactions in 6-hydroxydopamine-lesioned rats: evidence for pre- and postsynaptic influences by adenosine. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2 Topics: Adenosine; Animals; Female; Hydroxydopamines; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Levodopa; Motor Activity; Oxidopamine; Pregnancy; Purines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Purinergic; Theophylline	1988
Adenosine metabolism in human skin fibroblasts. The American journal of physiology, 1985, Volume: 248, Issue:1 Pt 1 Topics: Adenosine; Carbon Radioisotopes; Cells, Cultured; Child, Preschool; Fibroblasts; Humans; Hypoxanthine Phosphoribosyltransferase; Infant, Newborn; Kinetics; Lesch-Nyhan Syndrome; Male; Radioisotope Dilution Technique; Skin	1985
Pathophysiology of purine metabolism in man. Enzyme, 1974, Volume: 18, Issue:3 Topics: Adenosine; Alkaline Phosphatase; Amidinotransferases; Amidohydrolases; Glomerular Filtration Rate; Glucosephosphate Dehydrogenase; Gout; Guanine Nucleotides; Humans; Hypoxanthines; Kinetics; Lesch-Nyhan Syndrome; Pentosephosphates; Pentosyltransferases; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribose; Uric Acid; Xanthine Oxidase; Xanthines	1974
Adaptive significance of inosine and adenosine kinase activities in cultured human skin fibroblasts. Experimental cell research, 1972, Volume: 72, Issue:2 Topics: Adenine; Adenosine; Azaserine; Cells, Cultured; Fibroblasts; Guanine; Humans; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Phosphotransferases; Skin; Thymidine; Tritium	1972
Detailed comparison of the urinary excretion of purines in a patient with the Lesch-Nyhan syndrome and a control subject. Biochemical medicine, 1970, Volume: 4, Issue:2 Topics: Adenine; Adenosine; Athetosis; Child; Chromatography, Gel; Chromatography, Ion Exchange; Formamides; Formates; Humans; Hypoxanthines; Imidazoles; Intellectual Disability; Lesch-Nyhan Syndrome; Male; Methods; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribonucleosides; Self Mutilation; Spectrophotometry; Ultraviolet Rays; Xanthines	1970