Compounds > adenosine
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adenosine and Colorectal Neoplasms

adenosine has been researched along with Colorectal Neoplasms in 84 studies

Research

Studies (84)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.19)18.2507
2000's10 (11.90)29.6817
2010's9 (10.71)24.3611
2020's64 (76.19)2.80

Authors

AuthorsStudies
Fu, T; Ge, Y; Ren, J; Song, W; Xiang, R; Yuan, W1
Asai, A; Doki, Y; Eguchi, H; Ishii, H; Komoto, Y; Konno, M; Ofusa, K; Ohshiro, T; Taniguchi, M; Yamagata, A1
Hong, H; Huang, Z; Jiang, H; Jiang, P; Luo, C; Wu, R; Xie, J; Yin, H1
Feng, Y; Ge, Y; Liang, G; Liu, T; Pu, Y; Ren, Y; Wang, C; Xu, S; Yin, L; Zhang, Y1
Chang, Y; He, Y; Huang, H; Huang, S; Jiao, X; Jin, H; Jin, Z; Li, H; Li, M; Ren, G; Sun, W; Wang, C; Xie, Q; Zhang, N; Zhang, X1
Yu, ZL; Zhu, ZM1
Chu, XD; Ding, H; Guo, YG; Li, XG; Li, XY; Lin, ZB; Pan, JH; Pan, YL; Wang, L; Yang, YB; Zhang, YR; Zhao, Z1
Borde, C; Dillard, C; Escargueil, AE; Jourdren, L; Larsen, AK; Maréchal, V; Mohammad, A; Pramil, E; Puchois, V; Sabbah, M1
Bifulco, M; Covelli, V; D'Ursi, AM; Firoznezhad, M; Gazzerro, P; Grimaldi, M; Matteoli, G; Proto, MC; Randino, R; Rodriquez, M; Simone, V1
Bao, Y; Cai, Z; Chen, H; Ci, X; Gao, S; He, A; He, HH; Hezaveh, K; Kang, W; McGaha, T; Mo, Y; O'Brien, C; Rottapel, R; Soares, F; Su, P; Wang, L; Wang, S; Wong, CC; Wu, J; Xu, X; Yu, J; Zeng, Y; Zhai, J; Zheng, G; Zhu, L1
Huang, J; Smith, AO; Tong, H; Wei, H1
Chen, M; Chou, J; Gong, N; Guo, Y; Hu, G; Li, L; Li, X; Lin, C; Liu, T; Long, F; Ma, M; Tian, B; Xiao, H; Xie, C; Yang, K; Zhang, Y1
Feng, Q; Jin, G; Lin, W; Peng, X; Shao, Y; Wang, S; Wei, Y; Wu, J; Xu, X; Zhang, H1
An, R; Chen, S; Chu, Y; Gao, Y; Li, G; Wang, H; Wang, Y; Xie, X; Zhang, J1
He, L; Li, Y; Tan, Y; Wang, Y; Zhang, F1
Chen, W; Liu, J; Liu, Z; Wang, Y; Yu, T; Zhu, L; Zhu, W1
Bai, J; Cao, F; Duan, X; Wang, F; Yue, Q; Zhang, Y1
Ge, Y; Guo, L; Li, L; Quan, Q; Zhang, D; Zhao, H; Zhao, Y1
Chung, H; Han, NR; Kim, M; Kim, SI; Lee, CH; Lee, IP; Lee, SY; Min, YK; Noh, JY; Park, D; Park, T; Yun, SH1
Jiang, K; Shen, Z; Wang, B; Wang, L; Wang, Q; Wang, S; Yang, C; Ye, Y; Zhang, M; Zhang, Z; Zhao, L1
Chu, F; Li, K; Li, L; Wu, H; Xiao, X; Zhang, L; Zhang, Y1
Chen, B; Chen, Q; Fan, L; Gui, R; Hong, Y; Jiang, C; Qian, Q; Ren, X; Tian, S; Xie, X; Zhai, X; Zheng, H1
Chen, K; Dai, X; Xie, Y1
Mao, J; Qu, X; Tan, H; Wu, W; Xu, J; Yan, X; Yang, M1
Chen, J; Chen, X; Huang, L; Liang, D; Lin, S; Liu, H; Wen, C; Yang, X; Zhang, Y1
Bao, L; Gao, X; Ge, X; Jiang, X; Li, C; Li, J; Liu, L; Liu, M; Liu, Z; Song, Z; Zhan, Y; Zheng, D; Zheng, N1
Fuji, T; Fujiwara, T; Hata, N; Kishimoto, H; Kondo, Y; Michiue, H; Mori, Y; Nakamura, K; Shigeyasu, K; Takahashi, T; Takeda, S; Tazawa, H; Teraishi, F; Umeda, H; Umeda, Y; Yamamoto, H; Yano, S; Yasui, K; Yoshida, K; Yoshida, R1
Chen, W; Deng, J; Zhou, Y1
Bai, L; Huang, M; Huang, Z; Lin, J; Liu, X; Luo, Y; Peng, S; Shen, D; Tang, G; Wang, P; Wang, X; Xie, Y; Xu, G; Yu, H; Zhang, Y; Zhu, M; Zhuang, Z1
Cai, Y; Fei, YF; He, B; Jiang, GM; Shi, B; Sun, CL; Wang, C; Wang, H; Wei, W; Zhang, HS; Zhang, S; Zhang, ZY; Zhong, W1
Gu, W; Huang, J; Jiang, J; Liu, Z; Shao, Y; Song, X; Sun, H; Sun, R; Wu, C; Zhang, D; Zheng, X; Zhou, Y1
Bai, J; Bao, J; Chen, J; Hu, C; Kan, J; Lu, F; Tang, Q; Tian, Y; Wang, B; Yan, L; Ye, M; Yu, P; Zhong, Y1
Henault, D; Kadoury, S; Messaoudi, N; Montagnon, E; Rebolledo, R; Saber, R; Soucy, G; Stagg, J; Tang, A; Turcotte, S1
Lu, Q; Sun, Y; Wang, A; Wang, D; Wang, X; Yan, Z; Zeng, L1
Lin, Z; Song, Y; Yao, J; Yu, X1
Gong, X; Peng, F; Yi, J; Zhao, J1
Chakrabarti, P; Chatterjee, T; Dhar, J; Guha, D; Paul, D; Sa, G; Saha, T1
Liu, Y; Si, Z; Wang, X; Yu, L; Zhou, M1
Chen, D; Chen, N; Huang, J; Huang, S; Liang, S; Liu, S; Peng, P; Qin, M; Qiu, X; Wu, J1
Ge, L; Lin, Y; Ma, Z; Shi, H; Wu, L1
Chang, J; Gong, Y; Ke, J; Mei, S; Miao, X; Peng, X; Tian, J; Wang, C; Wang, X; Yang, N; Yang, Y; Ying, P; Zhang, Y; Zhong, R; Zhu, Y; Zou, D1
Lian, B; Lin, T; Ren, Y; Wang, Y; Zhang, H1
Chu, H; Du, M; Fu, Z; Gu, D; Li, S; Meng, Y; Wang, M; Wu, Y; Xu, K; Zhang, Z; Zhu, L1
Chen, X; He, B; Liu, X; Pan, B; Pan, Y; Sun, H; Sun, L; Wang, S; Xia, X; Xu, M; Xu, X; Zeng, K1
Cui, H; Dong, Z; Lei, Q; Li, L; Yang, J; Yang, L1
Achyut, BR; Arbab, AS; Bollag, RJ; Canning, M; Chang, CS; Cui, Y; Deng, L; Guo, G; Huang, L; Mellor, AL; Munn, DH; Rodriguez, PC; Shi, H; Xu, N; Yu, M1
Cao, M; Ding, Q; Lin, Y; Si, Y; Sun, S; Wang, JZ; Wei, JF; Xu, J; Zhu, L; Zhu, W1
Chen, M; Chen, XH; He, YT; Lu, RX; Meng, N; Wang, JZ; Yan, GR; Zhang, XL; Zhu, S1
Chen, X; He, B; Li, C; Liu, X; Pan, B; Pan, Y; Qin, J; Sun, H; Sun, L; Wang, S; Xu, M; Xu, T; Xu, X; Zeng, K1
Cheng, X; Guo, D; Huang, Y; Wang, J; Yuan, J; Zhang, J1
Antonioli, L; Benvenuti, L; Blandizzi, C; D'Antongiovanni, V; Fornai, M; Pellegrini, C1
Jiang, K; Shen, Z; Wang, B; Wang, Q; Wang, S; Yang, C; Ye, Y; Zhang, M; Zhang, W; Zhang, Z; Zhao, L1
Ghalamfarsa, G; Hajizadeh, F; Heydarzedeh Asl, S; Jadidi-Niaragh, F; Karoon Kiani, F; Masjedi, A; Peydaveisi, M; Sevbitov, A1
Dai, D; Feng, L; Jin, H; Li, J; Li, L; Shi, R; Song, P; Wang, C; Wang, X; Zhou, Q; Zhu, L1
Agrawal, K; Hui, H; Kang, Y; Li, N; Rana, TM; Tang, R; Wang, L; Yuan, J1
Chen, F; Chen, Y; Fu, S; Han, Y; Tang, W; Wang, G; Wang, Y; Xu, B; Xu, Y; Zhou, D1
Cai, Y; Johnson, CH; Khan, SA; Kurbatov, V; Lu, L; Zhang, Q; Zhang, Y1
Li, J; Li, X; Liang, L; Ma, Y; Yang, Y1
Chen, LF; Li, XM; Su, H; Wu, WY; Xiong, J; Zeng, Y; Zhang, Q; Zhou, Y; Zuo, L1
Bai, J; Chu, S; Gu, Y; Hou, P; Li, M; Li, Z; Lin, T; Meng, S; Zheng, J1
Chen, R; Fan, X; Hao, J; Hu, J; Jiang, X; Jiang, Y; Li, J; Li, R; Shen, Y; Wang, K; Wang, S; Wang, Y; Xu, D; Zhang, J; Zhu, J1
Kuai, D; Liu, H; Liu, T; Min, L; Shi, H; Yang, R; Zhang, S; Zhu, S1
Chen, C; Dang, Q; Guo, Y; Ji, Z; Kang, Q; Liu, J; Shao, B; Sun, Z; Wang, G; Wang, W; Yang, S; Yang, X; Yuan, W; Zhao, L; Zhou, Q1
Bissonnette, MB; Chang, R; Chen, C; Dong, L; Dougherty, U; Guo, P; Han, D; Lai, W; Li, J; Li, Y; Liang, G; Liu, J; Liu, Y; Shen, L; Sun, M; Wang, H; Wang, Z; Xu, MM; Zhang, Y1
Chen, C; Gan, M; Kong, J; Lai, M; Wang, S; Zhang, H; Zhang, Y1
Chen, J; Chen, W; Shi, L; Xue, M; Zhang, Z1
Battaglin, F; Berger, MD; Cao, S; Cremolini, C; Falcone, A; Heinemann, V; Lenz, HJ; Lo, JH; Loupakis, F; Millstein, J; Naseem, M; Puccini, A; Soni, S; Stintzing, S; Tokunaga, R; Zhang, W1
An, P; Chen, F; Chen, Z; Du, J; Jiang, G; Li, J; Liu, H; Lu, L; Luo, N; Shan, H; Tian, L; Wang, H; Wu, Y; Yang, X1
Chen, D; Chen, ZH; Hu, PS; Ju, HQ; Kang, TB; Li, B; Li, T; Li, X; Lin, D; Lin, JF; Wang, F; Wu, QN; Xie, D; Xu, RH; Zeng, ZL; Zheng, J; Zuo, Z1
Li, Q; Shen, H; Shu, N; Wang, Y; Xie, K; Zeng, L; Zhang, L1
Abdulla, MH; Al-Obeed, O; Alajez, NM; Aldahmash, A; Hamam, R; Kassem, M; Mohammed, MA; Vishnubalaji, R1
Cui, L; Han, W; Li, W; Ma, Y; Tian, Y; Wang, H; Wang, W; Yang, L; Zhao, X; Zhou, Z1
Han, SW; Kang, JK; Kim, HP; Kim, TY; Lee, SH; Song, SH1
Chan, MT; Cheyette, BN; Jiang, X; Kivimäe, S; Lee, PL; Li, J; Liu, ET; Stanton, LW; Tan, J; Yang, X; Yu, Q; Zhuang, L1
Aceto, E; Bernini, A; Carraro, F; Chessa, A; Civitelli, S; Giglioni, S; Leoncini, R; Pucci, A; Tanzini, G; Vannoni, D1
Blay, J; Hoskin, D; Mujoomdar, M1
Bernini, A; Carlucci, F; Civitelli, S; Di Pietro, MC; Leoncini, R; Marinello, E; Rosi, F; Tabucchi, A; Tanzini, G; Vannoni, D1
Bernini, A; Carlucci, F; Di Pietro, MC; Floccari, F; Leoncini, R; Marinello, E; Rosi, F; Santoro, A; Tabucchi, A; Tanzini, G; Vannoni, D1
Blay, J; Richard, CL; Tan, EY1
Baraldi, S; Benini, A; Borea, PA; Cattabriga, E; Feo, C; Gessi, S; Leung, E; Mac Lennan, S; Merighi, S; Mirandola, P; Varani, K1
Bapat, B; Chan, YM; Daftary, D; Dicks, E; Gallinger, SS; Green, RC; Knight, JA; McLaughlin, JR; Monga, N; Mrkonjic, M; Parfrey, PS; Pethe, VV; Raptis, S; Younghusband, BH1
Houlston, RS; Hubner, RA1
Burnham, LL; Carlson, CC; Dransfield, DT; Shanks, RA1
Allegra, CJ; Grem, JL; Trepel, JB; Yee, LK1

Reviews

7 review(s) available for adenosine and Colorectal Neoplasms

ArticleYear
N6-methyladenosine RNA modification and its interaction with regulatory non-coding RNAs in colorectal cancer.
    RNA biology, 2021, 11-12, Volume: 18, Issue:sup2

    Topics: Adenosine; Animals; Biomarkers, Tumor; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Methylation; MicroRNAs; Molecular Targeted Therapy; RNA, Circular; RNA, Long Noncoding; RNA, Messenger; RNA, Untranslated

2021
The Role of m6A Epigenetic Modification in the Treatment of Colorectal Cancer Immune Checkpoint Inhibitors.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adaptive Immunity; Adenosine; Animals; Biomarkers, Tumor; Colorectal Neoplasms; Disease Management; Disease Susceptibility; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Immune Checkpoint Proteins; Immunity, Innate; Treatment Outcome

2021
Interaction between N
    Molecular medicine (Cambridge, Mass.), 2023, 09-22, Volume: 29, Issue:1

    Topics: Adenosine; Colorectal Neoplasms; Epigenesis, Genetic; Humans; Tumor Microenvironment

2023
Research progress of N6-methyladenosine in colorectal cancer: A review.
    Medicine, 2023, Nov-24, Volume: 102, Issue:47

    Topics: Adenosine; Animals; Colorectal Neoplasms; Humans; Mammals; MicroRNAs; RNA, Long Noncoding; RNA, Messenger

2023
The Adenosine System at the Crossroads of Intestinal Inflammation and Neoplasia.
    International journal of molecular sciences, 2020, Jul-18, Volume: 21, Issue:14

    Topics: Adenosine; Animals; Colitis-Associated Neoplasms; Colorectal Neoplasms; Dextran Sulfate; Humans; Immune System; Inflammation; Inflammatory Bowel Diseases; Receptors, Purinergic P1; Signal Transduction

2020
Adenosine and adenosine receptors in colorectal cancer.
    International immunopharmacology, 2020, Volume: 87

    Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Colorectal Neoplasms; Humans; Receptors, Purinergic P1

2020
N
    Theranostics, 2021, Volume: 11, Issue:6

    Topics: Adenosine; Animals; Biomarkers, Tumor; Colorectal Neoplasms; Disease Progression; Humans; RNA, Messenger; RNA, Untranslated

2021

Trials

1 trial(s) available for adenosine and Colorectal Neoplasms

ArticleYear
Identification and verification of m6A-related miRNAs correlated with prognosis and immune microenvironment in colorectal cancer.
    Medicine, 2023, Nov-17, Volume: 102, Issue:46

    Topics: Adenosine; Colorectal Neoplasms; Humans; Immunotherapy; MicroRNAs; Prognosis; Tumor Microenvironment

2023

Other Studies

76 other study(ies) available for adenosine and Colorectal Neoplasms

ArticleYear
N6-Methyladenosine-Related lncRNA Signature Predicts the Overall Survival of Colorectal Cancer Patients.
    Genes, 2021, 08-31, Volume: 12, Issue:9

    Topics: Adenosine; Biomarkers, Tumor; Colorectal Neoplasms; Datasets as Topic; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Nomograms; Risk Assessment; RNA, Long Noncoding

2021
Single-molecule RNA sequencing for simultaneous detection of m6A and 5mC.
    Scientific reports, 2021, 09-29, Volume: 11, Issue:1

    Topics: Adenosine; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Methylation; MicroRNAs; Sequence Analysis, RNA; Single Molecule Imaging

2021
Elevated N6-Methyladenosine RNA Levels in Peripheral Blood Immune Cells: A Novel Predictive Biomarker and Therapeutic Target for Colorectal Cancer.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adenosine; Biomarkers, Tumor; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Monocytes; RNA

2021
Downregulation of microRNA-6125 promotes colorectal cancer growth through YTHDF2-dependent recognition of N6-methyladenosine-modified GSK3β.
    Clinical and translational medicine, 2021, Volume: 11, Issue:10

    Topics: Adenosine; Animals; Colorectal Neoplasms; Disease Models, Animal; Down-Regulation; Glycogen Synthase Kinase 3 beta; Mice; MicroRNAs; RNA-Binding Proteins

2021
Construction of an N6-methyladenosine lncRNA- and immune cell infiltration-related prognostic model in colorectal cancer.
    Protoplasma, 2022, Volume: 259, Issue:4

    Topics: Adenosine; Biomarkers, Tumor; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Prognosis; RNA, Long Noncoding; Tumor Microenvironment

2022
Comprehensive Analysis of N6-Methyladenosine-Related lncRNA Signature for Predicting Prognosis and Immune Cell Infiltration in Patients with Colorectal Cancer.
    Disease markers, 2021, Volume: 2021

    Topics: Adenosine; Biomarkers, Tumor; Cell Movement; Colorectal Neoplasms; Dendritic Cells; Humans; Lymphocytes, Tumor-Infiltrating; Prognosis; RNA Processing, Post-Transcriptional; RNA, Long Noncoding; Tumor Microenvironment

2021
Expression Pattern of Purinergic Signaling Components in Colorectal Cancer Cells and Differential Cellular Outcomes Induced by Extracellular ATP and Adenosine.
    International journal of molecular sciences, 2021, Oct-25, Volume: 22, Issue:21

    Topics: Adenosine; Adenosine Triphosphate; Apoptosis; Biomarkers, Tumor; Calcium; Calcium Signaling; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; Extracellular Space; Gene Expression Regulation, Neoplastic; Humans; Receptors, Purinergic; Transcriptome; Tumor Cells, Cultured

2021
Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs.
    Molecules (Basel, Switzerland), 2021, Nov-25, Volume: 26, Issue:23

    Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Computer Simulation; Drug Screening Assays, Antitumor; Geranyltranstransferase; HCT116 Cells; Humans; Mevalonic Acid; Mice; Structure-Activity Relationship; User-Computer Interface

2021
N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer.
    Gastroenterology, 2022, Volume: 162, Issue:4

    Topics: Adenosine; Animals; Carcinogenesis; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Liposomes; Mice; Nanoparticles; Rho Guanine Nucleotide Exchange Factors; rhoA GTP-Binding Protein; RNA-Binding Proteins; RNA, Small Interfering

2022
The N
    Molecular cancer, 2022, 03-19, Volume: 21, Issue:1

    Topics: Adenosine; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; MicroRNAs; Placenta Growth Factor; RNA, Circular

2022
A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer.
    Cell death & disease, 2022, 04-02, Volume: 13, Issue:4

    Topics: Adenosine; Adenosine Deaminase; Carrier Proteins; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; RNA; Tumor Microenvironment

2022
Single-cell N
    Journal of translational medicine, 2022, 05-04, Volume: 20, Issue:1

    Topics: Adenosine; Biomarkers, Tumor; Cell Communication; Colorectal Neoplasms; Humans; Immunotherapy; RNA; Tumor Microenvironment

2022
N
    Bioengineered, 2022, Volume: 13, Issue:5

    Topics: Adenosine; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Glycolysis; Hexokinase; Humans; Methyltransferases; RNA-Binding Proteins

2022
METTL3 promotes colorectal cancer metastasis by stabilizing PLAU mRNA in an m6A-dependent manner.
    Biochemical and biophysical research communications, 2022, 07-23, Volume: 614

    Topics: Adenosine; Cell Line, Tumor; Colorectal Neoplasms; Humans; Membrane Proteins; Methyltransferases; RNA, Messenger

2022
Characterization of m6A Methylation Modification Patterns in Colorectal Cancer Determines Prognosis and Tumor Microenvironment Infiltration.
    Journal of immunology research, 2022, Volume: 2022

    Topics: Adenosine; Colorectal Neoplasms; Humans; Methylation; Prognosis; Tumor Microenvironment

2022
YTHDF3 Facilitates eIF2AK2 and eIF3A Recruitment on mRNAs to Regulate Translational Processes in Oxaliplatin-Resistant Colorectal Cancer.
    ACS chemical biology, 2022, 07-15, Volume: 17, Issue:7

    Topics: Adenosine; Colorectal Neoplasms; Drug Resistance, Neoplasm; eIF-2 Kinase; Eukaryotic Initiation Factor-3; Humans; Oxaliplatin; RNA; RNA-Binding Proteins; RNA, Messenger

2022
Additive Effect of CD73 Inhibitor in Colorectal Cancer Treatment With CDK4/6 Inhibitor Through Regulation of PD-L1.
    Cellular and molecular gastroenterology and hepatology, 2022, Volume: 14, Issue:4

    Topics: Adenosine; Animals; B7-H1 Antigen; Cetuximab; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Humans; Immune Checkpoint Proteins; Mice; Programmed Cell Death 1 Receptor

2022
N6-methyladenosine demethylase ALKBH5 suppresses colorectal cancer progression potentially by decreasing PHF20 mRNA methylation.
    Clinical and translational medicine, 2022, Volume: 12, Issue:8

    Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Carcinogenesis; Cell Line, Tumor; Colorectal Neoplasms; DNA-Binding Proteins; Humans; Methylation; RNA, Messenger; Transcription Factors

2022
Identification and Validation of an m6A-Related LncRNA Signature to Predict Progression-Free Survival in Colorectal Cancer.
    Pathology oncology research : POR, 2022, Volume: 28

    Topics: Adenosine; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Progression-Free Survival; RNA, Long Noncoding

2022
N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis.
    Cell death & disease, 2022, 09-20, Volume: 13, Issue:9

    Topics: Adenosine; Cell Line, Tumor; Colorectal Neoplasms; Disks Large Homolog 4 Protein; Gene Expression Regulation, Neoplastic; Glucose; Glucosephosphate Dehydrogenase; Humans; MicroRNAs; Pentose Phosphate Pathway; RNA, Circular

2022
WTAP Mediated the N6-methyladenosine Modification of PDK4 to Regulate the Malignant Behaviors of Colorectal Cancer Cells
    Current medicinal chemistry, 2023, Volume: 30, Issue:29

    Topics: Adenosine; Animals; Binding Sites; Cell Cycle Proteins; Colorectal Neoplasms; Disease Models, Animal; Humans; Mice; RNA Splicing Factors

2023
Identification of a novel prognostic signature correlated with epithelial-mesenchymal transition, N6-methyladenosine modification, and immune infiltration in colorectal cancer.
    Cancer medicine, 2023, Volume: 12, Issue:5

    Topics: Adenosine; Aged; Carrier Proteins; Colorectal Neoplasms; Cytokines; Epithelial-Mesenchymal Transition; Female; Genes, Regulator; Humans; Male; Mitochondrial Proteins; Neoplasm Proteins; Prognosis

2023
METTL3 promotes colorectal cancer metastasis by promoting the maturation of pri-microRNA-196b.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:8

    Topics: Adenosine; Cell Movement; Colorectal Neoplasms; Humans; Methyltransferases; MicroRNAs

2023
N6-methyladenosine-modified circular RNA QSOX1 promotes colorectal cancer resistance to anti-CTLA-4 therapy through induction of intratumoral regulatory T cells.
    Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2022, Volume: 65

    Topics: Adenosine; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Methyltransferases; MicroRNAs; Oxidoreductases Acting on Sulfur Group Donors; RNA, Circular; T-Lymphocytes, Regulatory

2022
ADAR1 is a promising risk stratification biomarker of remnant liver recurrence after hepatic metastasectomy for colorectal cancer.
    Scientific reports, 2023, 02-06, Volume: 13, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Biomarkers; Colorectal Neoplasms; Humans; Liver Neoplasms; Metastasectomy; Risk Assessment; RNA; RNA-Binding Proteins

2023
The construction of a novel ferroptosis-related lncRNA model to predict prognosis in colorectal cancer patients.
    Medicine, 2023, Mar-10, Volume: 102, Issue:10

    Topics: Adenosine; Apoptosis; Biomarkers, Tumor; Colorectal Neoplasms; Ferroptosis; Humans; Methyltransferases; Prognosis; RNA, Long Noncoding

2023
RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A-YTHDF2-dependent manner.
    Clinical and translational medicine, 2023, Volume: 13, Issue:5

    Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Carcinogenesis; Cell Transformation, Neoplastic; Colorectal Neoplasms; Humans; rab5 GTP-Binding Proteins; RNA-Binding Proteins

2023
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
    Journal of experimental & clinical cancer research : CR, 2023, Jun-20, Volume: 42, Issue:1

    Topics: Adenosine; Cell Line, Tumor; Colorectal Neoplasms; Glycolysis; Humans; Methyltransferases; Prognosis; RNA

2023
ALKBH5/YTHDF2-mediated m6A modification of circAFF2 enhances radiosensitivity of colorectal cancer by inhibiting Cullin neddylation.
    Clinical and translational medicine, 2023, Volume: 13, Issue:7

    Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Colorectal Neoplasms; Cullin Proteins; Humans; Radiation Tolerance; RNA-Binding Proteins; RNA, Circular; Transcription Factors

2023
WTAP activates MAPK signaling through m6A methylation in VEGFA mRNA-mediated by YTHDC1 to promote colorectal cancer development.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:8

    Topics: Adenosine; Animals; Biological Assay; Colorectal Neoplasms; Humans; Methylation; Mice; Mice, Nude

2023
Radiomics using computed tomography to predict CD73 expression and prognosis of colorectal cancer liver metastases.
    Journal of translational medicine, 2023, 07-27, Volume: 21, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Colorectal Neoplasms; Humans; Liver Neoplasms; Prognosis; Retrospective Studies; Tomography, X-Ray Computed

2023
m
    Aging, 2023, 08-29, Volume: 15, Issue:16

    Topics: Adenosine; B7-H1 Antigen; Colorectal Neoplasms; Humans; Immune Evasion; Methyltransferases; Programmed Cell Death 1 Receptor

2023
METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3.
    Scientific reports, 2023, 10-12, Volume: 13, Issue:1

    Topics: Adenosine; Animals; Cell Cycle Proteins; Colorectal Neoplasms; Disease Models, Animal; Humans; Methyltransferases; Mice; Mice, Nude; RNA-Binding Proteins; RNA, Messenger

2023
Adenosine dialdehyde, a methyltransferase inhibitor, induces colorectal cancer cells apoptosis by regulating PIMT:p53 interaction.
    Biochemical and biophysical research communications, 2023, 12-03, Volume: 684

    Topics: Adenosine; Apoptosis; bcl-2-Associated X Protein; Colonic Neoplasms; Colorectal Neoplasms; Humans; Methyltransferases; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Tumor Suppressor Protein p53

2023
m6A modified BACE1-AS contributes to liver metastasis and stemness-like properties in colorectal cancer through TUFT1 dependent activation of Wnt signaling.
    Journal of experimental & clinical cancer research : CR, 2023, Nov-21, Volume: 42, Issue:1

    Topics: Adenosine; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cell Line, Tumor; Colorectal Neoplasms; Dental Enamel Proteins; Humans; Liver Neoplasms; RNA-Binding Proteins; RNA, Antisense; Wnt Signaling Pathway

2023
ANKLE1 N
    International journal of cancer, 2020, 06-15, Volume: 146, Issue:12

    Topics: Adenosine; Aged; Carcinogenesis; Case-Control Studies; Cell Proliferation; Colorectal Neoplasms; DNA Methylation; Endonucleases; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genetic Predisposition to Disease; Genomic Instability; HCT116 Cells; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide

2020
An adenosine derivative (IFC-305) reduced the risk of radiation-induced intestinal toxicity in the treatment of colon cancer by suppressing the methylation of PPAR-r promoter.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 118

    Topics: Adenosine; Aged; Animals; Colorectal Neoplasms; DNA Methylation; Female; Humans; Male; Mice, Inbred C57BL; Middle Aged; PPAR gamma; Promoter Regions, Genetic; Radiation Injuries; Radiation Injuries, Experimental; Radiation-Protective Agents

2019
Genetic variants in m6A modification genes are associated with colorectal cancer risk.
    Carcinogenesis, 2020, 03-13, Volume: 41, Issue:1

    Topics: Adenosine; Aged; Case-Control Studies; Cell Line, Tumor; Colorectal Neoplasms; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Male; Methylation; Middle Aged; Polymorphism, Single Nucleotide; RNA Processing, Post-Transcriptional; RNA, Messenger

2020
RETRACTED: METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing
    Molecular therapy : the journal of the American Society of Gene Therapy, 2020, 02-05, Volume: 28, Issue:2

    Topics: Adenosine; Animals; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Methyltransferases; Mice; MicroRNAs; RNA Interference; Xenograft Model Antitumor Assays

2020
Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer.
    Clinical epigenetics, 2019, 12-30, Volume: 11, Issue:1

    Topics: Adenosine; Animals; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; HCT116 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Male; Methylation; Mice; Mice, Nude; Neoplasm Transplantation; Phenylurea Compounds; Prognosis; Proto-Oncogene Proteins c-myc

2019
CD73 on cancer-associated fibroblasts enhanced by the A
    Nature communications, 2020, 01-24, Volume: 11, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Cancer-Associated Fibroblasts; Cell Line, Tumor; Colorectal Neoplasms; Disease Progression; Drug Synergism; Hematopoietic Stem Cells; Humans; Lymphocytes, Tumor-Infiltrating; Mice, Inbred C57BL; Models, Biological; Neutralization Tests; Receptor, Adenosine A2B; Transcriptome; Treatment Outcome; Tumor Microenvironment; Up-Regulation

2020
Methyltransferase like 3 promotes colorectal cancer proliferation by stabilizing CCNE1 mRNA in an m6A-dependent manner.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:6

    Topics: Adenosine; Animals; Butyrates; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin E; Down-Regulation; Gastrointestinal Microbiome; Gene Expression Regulation, Neoplastic; Humans; Methyltransferases; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Oncogene Proteins; Prognosis; RNA Stability; RNA, Messenger; Up-Regulation

2020
An oncopeptide regulates m
    Nature communications, 2020, 04-03, Volume: 11, Issue:1

    Topics: Adenosine; Animals; Binding Sites; Carcinogenesis; Cell Line, Tumor; Colorectal Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Methylation; Mice; Middle Aged; Prognosis; Proto-Oncogene Proteins c-myc; RNA Processing, Post-Transcriptional; RNA Stability; RNA-Binding Proteins; RNA, Long Noncoding; RNA, Messenger; Survival Analysis; Tissue Array Analysis; Xenograft Model Antitumor Assays

2020
METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer.
    Molecular cancer, 2020, 06-17, Volume: 19, Issue:1

    Topics: Adenosine; Animals; Apoptosis; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Prognosis; SOXC Transcription Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
Gene signature and prognostic merit of M6a regulators in colorectal cancer.
    Experimental biology and medicine (Maywood, N.J.), 2020, Volume: 245, Issue:15

    Topics: Adenosine; Colorectal Neoplasms; DNA Copy Number Variations; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mutation; Mutation Rate; Neoplasm Proteins; Prognosis; Survival Analysis

2020
Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing.
    Epigenetics, 2021, Volume: 16, Issue:4

    Topics: Adenosine; Androgen-Binding Protein; Colorectal Neoplasms; DNA Methylation; Epigenome; Humans; Proteins; Spectrin; Transcription Factors; Transcriptome

2021
β-catenin represses miR455-3p to stimulate m6A modification of HSF1 mRNA and promote its translation in colorectal cancer.
    Molecular cancer, 2020, 08-24, Volume: 19, Issue:1

    Topics: Adenosine; Animals; Apoptosis; beta Catenin; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Heat Shock Transcription Factors; Humans; Methylation; Mice; MicroRNAs; Models, Biological; Protein Biosynthesis; RNA Interference; RNA, Messenger; Xenograft Model Antitumor Assays

2020
m
    The EMBO journal, 2020, 10-15, Volume: 39, Issue:20

    Topics: Adenosine; Animals; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Chemokine CXCL10; Chemokine CXCL9; Colorectal Neoplasms; Cytokines; Humans; Immune Checkpoint Inhibitors; Immunohistochemistry; Immunotherapy; Interferon Regulatory Factor-1; Interferon-gamma; Melanoma; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Programmed Cell Death 1 Receptor; RNA-Binding Proteins; RNA-Seq; STAT1 Transcription Factor; Tumor Microenvironment

2020
METTL3/YTHDF2 m6A axis accelerates colorectal carcinogenesis through epigenetically suppressing YPEL5.
    Molecular oncology, 2021, Volume: 15, Issue:8

    Topics: Adenosine; Carcinogenesis; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; Epigenesis, Genetic; Humans; Methyltransferases; Prognosis; RNA-Binding Proteins

2021
Gene Alterations of N6-Methyladenosine (m
    BioMed research international, 2020, Volume: 2020

    Topics: Adenosine; Aged; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Colorectal Neoplasms; Databases, Genetic; Disease-Free Survival; DNA Copy Number Variations; Female; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Male; Multivariate Analysis; Mutation; Nerve Tissue Proteins; Prognosis; Proportional Hazards Models; RNA Splicing Factors; RNA, Messenger

2020
Comprehensive analysis of lncRNAs N
    Aging, 2021, 01-20, Volume: 13, Issue:3

    Topics: Adenosine; Carcinoma; Case-Control Studies; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Methylation; RNA, Long Noncoding

2021
LINC00460/DHX9/IGF2BP2 complex promotes colorectal cancer proliferation and metastasis by mediating HMGA1 mRNA stability depending on m6A modification.
    Journal of experimental & clinical cancer research : CR, 2021, Feb-01, Volume: 40, Issue:1

    Topics: Adenosine; Adult; Aged; Animals; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; DEAD-box RNA Helicases; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HMGA1a Protein; Humans; Male; Mice; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Prognosis; Protein Binding; RNA Stability; RNA-Binding Proteins; RNA, Long Noncoding

2021
The differentiation of colorectal cancer is closely relevant to m6A modification.
    Biochemical and biophysical research communications, 2021, 03-26, Volume: 546

    Topics: Adenosine; Butyric Acid; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Colorectal Neoplasms; Contact Inhibition; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methyltransferases; Middle Aged; Protein Biosynthesis; RNA Splicing Factors; Transcription, Genetic

2021
Aberrant expression of m
    Life sciences, 2021, May-15, Volume: 273

    Topics: Adenocarcinoma; Adenoma; Adenosine; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; DNA Methylation; Eukaryotic Initiation Factor-3; Female; Follow-Up Studies; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Nerve Tissue Proteins; Prognosis; RNA Splicing Factors; RNA-Binding Proteins; RNA, Messenger

2021
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization.
    Theranostics, 2021, Volume: 11, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Aged; Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Nucleus; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; Humans; Male; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Prognosis; RNA, Circular; Signal Transduction; Smad3 Protein; Transcription Factors; YAP-Signaling Proteins

2021
The loss of RNA N
    Cancer cell, 2021, 07-12, Volume: 39, Issue:7

    Topics: Adenosine; Animals; Carcinoma, Lewis Lung; CD8-Positive T-Lymphocytes; Colorectal Neoplasms; Cytokines; Female; Humans; Lymphocyte Activation; Melanoma, Experimental; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Minor Histocompatibility Antigens; Neoplasms; Receptors, Cytokine; Tumor Microenvironment; Tumor-Associated Macrophages

2021
Methyl CpG binding protein 2 promotes colorectal cancer metastasis by regulating N
    Cancer science, 2021, Volume: 112, Issue:8

    Topics: Adenosine; Animals; Cell Line, Tumor; Colorectal Neoplasms; Disease Progression; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Methyl-CpG-Binding Protein 2; Methyltransferases; Mice; Neoplasm Transplantation; RNA Stability; Up-Regulation

2021
N1-methyladenosine profiling of long non-coding RNA in colorectal cancer.
    IUBMB life, 2021, Volume: 73, Issue:10

    Topics: Adenosine; Chromosome Mapping; Cluster Analysis; Colorectal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Ontology; Humans; Immunoprecipitation; Methylation; RNA, Long Noncoding; Sequence Analysis, RNA

2021
Prognostic Effect of Adenosine-related Genetic Variants in Metastatic Colorectal Cancer Treated With Bevacizumab-based Chemotherapy.
    Clinical colorectal cancer, 2019, Volume: 18, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apyrase; Bevacizumab; Biomarkers, Tumor; Camptothecin; Cetuximab; Cohort Studies; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; GPI-Linked Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Receptors, Purinergic P1; Survival Rate

2019
m
    Molecular cancer, 2019, 04-13, Volume: 18, Issue:1

    Topics: Adenosine; Animals; Base Sequence; Cell Line, Tumor; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; F-Box Proteins; Female; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Nude; Neoplasm Staging; Nuclear Proteins; Nucleic Acid Conformation; RNA, Long Noncoding; Signal Transduction; Survival Analysis; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays; Zinc Finger E-box-Binding Homeobox 1

2019
METTL3 facilitates tumor progression via an m
    Molecular cancer, 2019, 06-24, Volume: 18, Issue:1

    Topics: Adenosine; Animals; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Methyltransferases; Mice; Neoplasm Transplantation; Prognosis; RNA-Binding Proteins; Sequence Analysis, RNA; Signal Transduction; SOXB1 Transcription Factors; Up-Regulation

2019
[Effects of adenosine on hMLH1 methylation of human colorectal cancer cells].
    Zhonghua yi xue za zhi, 2014, Apr-29, Volume: 94, Issue:16

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Humans; MutL Protein Homolog 1; Nuclear Proteins

2014
Genome-wide mRNA and miRNA expression profiling reveal multiple regulatory networks in colorectal cancer.
    Cell death & disease, 2015, Jan-22, Volume: 6

    Topics: Adenosine; Adult; Aged; Base Sequence; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genome, Human; Humans; Male; MicroRNAs; Middle Aged; Molecular Sequence Data; Polycomb Repressive Complex 2; RNA, Messenger

2015
Proteinase-activated receptor 2 promotes cancer cell migration through RNA methylation-mediated repression of miR-125b.
    The Journal of biological chemistry, 2015, Oct-30, Volume: 290, Issue:44

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Binding Sites; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Methylation; Methyltransferases; MicroRNAs; Oligopeptides; Oligoribonucleotides; Protein Binding; Receptor, PAR-2; RNA, Neoplasm; RNA, Small Interfering; Signal Transduction; Tumor Microenvironment

2015
Identification of Diverse Adenosine-to-Inosine RNA Editing Subtypes in Colorectal Cancer.
    Cancer research and treatment, 2017, Volume: 49, Issue:4

    Topics: Adenosine; Biomarkers, Tumor; Cell Line, Tumor; Colorectal Neoplasms; Gene Expression Profiling; Humans; Inosine; Reproducibility of Results; RNA Editing; Sequence Analysis, DNA; Transcriptome

2017
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.
    Cancer cell, 2008, Volume: 13, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Adenosylhomocysteinase; Apoptosis; Azacitidine; beta Catenin; Colorectal Neoplasms; Decitabine; Dishevelled Proteins; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HCT116 Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Oligonucleotide Array Sequence Analysis; Phosphoproteins; Promoter Regions, Genetic; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection; Wnt Proteins

2008
Adenosine kinase gene expression in human colorectal cancer.
    Nucleosides, nucleotides & nucleic acids, 2008, Volume: 27, Issue:6

    Topics: Adenosine; Adenosine Kinase; Aged; Aged, 80 and over; Biopsy; Cell Proliferation; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Intestines; Male; Middle Aged; Mucous Membrane; RNA, Messenger

2008
Adenosine stimulation of the proliferation of colorectal carcinoma cell lines. Roles of cell density and adenosine metabolism.
    Biochemical pharmacology, 2003, Nov-01, Volume: 66, Issue:9

    Topics: Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Adenosine Triphosphate; Cell Count; Cell Division; Colorectal Neoplasms; Culture Media; DNA; Humans; Tumor Cells, Cultured

2003
Enzyme activities controlling adenosine levels in normal and neoplastic tissues.
    Medical oncology (Northwood, London, England), 2004, Volume: 21, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine Monophosphate; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Mucous Membrane; Purine-Nucleoside Phosphorylase

2004
Metabolism of adenosine in human colorectal tumour.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Adenosine; Aged; Aged, 80 and over; Colon; Colorectal Neoplasms; Cyclic AMP; Female; Humans; Male; Middle Aged; Mucous Membrane; Neoplasm Metastasis; Purines; Tumor Cells, Cultured

2004
Adenosine upregulates CXCR4 and enhances the proliferative and migratory responses of human carcinoma cells to CXCL12/SDF-1alpha.
    International journal of cancer, 2006, Nov-01, Volume: 119, Issue:9

    Topics: Adenosine; Cell Division; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Chemokines, CXC; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Receptors, CXCR4

2006
Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: focus on the A(3) adenosine subtype.
    Journal of cellular physiology, 2007, Volume: 211, Issue:3

    Topics: Adenocarcinoma; Adenosine; Blotting, Western; Caco-2 Cells; Cell Division; Colorectal Neoplasms; Cyclic AMP; HT29 Cells; Humans; Ligands; Radioligand Assay; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Thymidine

2007
MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer.
    Journal of the National Cancer Institute, 2007, Mar-21, Volume: 99, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Carrier Proteins; Case-Control Studies; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA Repair; Female; Gene Frequency; Genotype; Guanine; Humans; Male; Microsatellite Instability; Middle Aged; MutL Protein Homolog 1; MutS Homolog 2 Protein; Newfoundland and Labrador; Nuclear Proteins; Odds Ratio; Ontario; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Research Design; Risk Assessment; Risk Factors; Surveys and Questionnaires

2007
Re: MLH1 93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer.
    Journal of the National Cancer Institute, 2007, Oct-03, Volume: 99, Issue:19

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Colorectal Neoplasms; Gene Frequency; Genetic Predisposition to Disease; Guanine; Humans; Microsatellite Instability; MutL Protein Homolog 1; Newfoundland and Labrador; Nuclear Proteins; Ontario; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Registries; Risk Assessment; Risk Factors

2007
8-Cl-adenosine induces differentiation in LS174T cells.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Cell Differentiation; Cell Division; Colorectal Neoplasms; Humans; Oncogene Protein p21(ras); Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Metabolism and RNA incorporation of cyclopentenyl cytosine in human colorectal cancer cells.
    Biochemical pharmacology, 1992, Apr-01, Volume: 43, Issue:7

    Topics: Adenosine; Cell Survival; Colorectal Neoplasms; Cytidine; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Leukemia; Methanol; Ribonucleotides; RNA, Neoplasm; Time Factors; Tumor Cells, Cultured

1992