Compounds > adenosine
Page last updated: 2024-08-24

adenosine and Colonic Neoplasms

adenosine has been researched along with Colonic Neoplasms in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199012 (19.67)18.7374
1990's9 (14.75)18.2507
2000's10 (16.39)29.6817
2010's16 (26.23)24.3611
2020's14 (22.95)2.80

Authors

AuthorsStudies
Li, Y; Lu, Y; Ma, L; Man, S; Mao, Y; Wang, Y; Yang, Z1
Du, G; Li, H; Liu, T; Luo, F; Ma, J; Shen, J; Zhao, H1
Ding, R; Li, Y; Liu, P; Pan, D; Wu, T; Xing, L; Yang, R; Yang, X; Zhang, X1
Dong, Y; Liu, T; Lu, Y; Ma, L; Man, S; Zhao, X1
Chen, J; Liu, L; Qiao, H; Shang, B; Wang, L1
Chakrabarti, P; Chatterjee, T; Dhar, J; Guha, D; Paul, D; Sa, G; Saha, T1
Jin, LP; Liu, T; Sun, YW; Tai, JD1
Jin, L; Li, C; Liu, T; Wang, L1
Kaneko, H; Kang, M; Meng, F; Shimamoto, F; Song, J; Tang, B; Zhang, B; Zhang, Y1
Shao, J; Song, H; Wang, J; Xu, D1
Chen, Q; Chen, T; Chen, X; Gong, A; Liang, R; Mathy, NW; Tian, K; Xu, J; Yu, T1
Akashi, K; Ariyama, H; Baba, E; Ito, M; Kusaba, H; Ohmura, H; Tsuchihashi, K; Tsuruta, N; Yamaguchi, K1
Min, Z; Tan, J; Wang, T; Wu, D; Yang, Z; Yu, B1
Chen, H; Chen, L; Chen, Y; Chong, W; Du, F; Fang, Z; Jia, S; Li, L; Liu, J; Liu, Y; Shang, L; Wang, Z; Wu, H1
Huang, L; Kong, W; Li, P; Zhu, J; Zhu, S1
Zhang, X; Zhang, Z1
Bowser, JL; Eltzschig, HK; Phan, LH1
Hill, RA; Hosain, SB; Jois, SD; Khiste, SK; Liu, YY; Roy, KR; Tackett, AJ; Uddin, MB; Zhao, Y1
Chen, H; Cheng, Q; Huang, R; Li, S; Qian, Y; Shao, Z; Wang, H; Xiang, M; Xie, R; Xu, N; Xu, Q; Zhou, Z1
Grden, M; Kitowska, A; Maciejewska, I; Pawelczyk, T; Sakowicz-Burkiewicz, M; Szutowicz, A1
Chen, P; Hou, D; Liu, F; Liu, H; Liu, J; Lv, B; Ma, Y; Song, EJ; Yang, D; Yu, S; Zhang, Q1
Choi, MG; Hasan, T; Kim, IW; Kim, JH; Park, JM; Roh, YJ1
Cabrera-Fuentes, HA; Cherepanov, V; Kim, MH; Serebruany, VL1
Ahlmanner, F; Bastid, J; Börjesson, L; Fredin, K; Gustavsson, B; Langenes, V; Ndah, TG; Quiding-Järbrink, M; Stenstad, H; Sundström, P; Theander, L1
Cabezas-Herrera, J; García-Cánovas, F; Navarro-Perán, E; Rodríguez-López, JN; Sánchez-Del-Campo, L1
Nakano, T; Nishizaki, T; Saito, M; Yaguchi, T; Yasuda, Y1
Bottini, E; Cozzoli, E; Gloria-Bottini, F; Saccucci, P; Spina, C1
Carrigan, SO; Otley, AR; Stadnyk, AW1
Fu, LW; Liang, YJ; Su, XD; Wang, F; Wu, XP1
Gorincioi, E; Rajabi, M; Santaniello, E1
Benoit, YD; Gudas, LJ; Laursen, KB; Lipkin, SM; Witherspoon, MS1
Bonithon-Kopp, C; Bouvier, AM; Chapusot, C; Ecarnot-Laubriet, A; Faivre, J; Laurent Puig, P; Martin, L; Piard, F; Ponnelle, T; Rageot, D1
Arich, A; Bar-Yehuda, S; Dreznick, Z; Fishman, P; Madi, L; Ohana, G; Rath-Wolfson, L; Silberman, D; Slosman, G1
Bar-Yehuda, S; Barer, F; Erlanger, A; Fishman, P; Madi, L; Ochaion, A; Ohana, G1
Bar-Yehuda, S; Fishman, P; Gery, S; Madi, L; Shkapenuk, M; Silberman, D1
Barrett, DA; Fouladi-Nashta, AA; Halliday, N; Li, D; Sinclair, KD; Singh, R1
Blay, J; Hoskin, DW; Richard, CL; Tan, EY; Zhang, H1
Baraldi, PG; Benini, A; Borea, PA; Gessi, S; Leung, E; Maclennan, S; Merighi, S; Mirandola, P; Simioni, C; Varani, K1
Chen, H; Chen, YH; Clarke, S; Josef-Lenz, H; Kuhlenkamp, J; Laird, PW; Li, T; Lin, M; Lu, SC; Mato, JM; Sodir, NM; Xia, M; Yang, H1
Glazer, RI; Knode, MC1
Dexter, DL; Parks, RE; Savarese, TM1
Abeles, RH; Dexter, DL; Ghoda, LY; Parks, RE; Savarese, TM; Trackman, PC1
Glazer, RI; Lloyd, LS1
Hallett, MB; Hiscox, S; Jiang, WG; Nakamura, T; Puntis, MC; Singhrao, SK1
Blay, J; Hoskin, DW; MacKenzie, WM2
Isselhard, W; Michalk, DV; Minor, T; Paas, S; Sonntag, A; Wingenfeld, P1
Blay, J; Hoskin, DW; White, TD1
Günther, S; Martin, D; Meisel, H; Schlimme, E1
Chheda, GB1
Borek, E; Davis, GE; Gehrke, CW; Kuo, KC; Suits, RD; Waalkes, TP1
Dho, S; Foskett, JK; Stewart, K1
Cabantchik, ZI; Eidelman, O; Fox, C; Guay-Broder, C; Jacobson, KA; Pollard, HB; Turner, RJ; van Galen, PJ1
Hoffman, M; O'Connor, CJ; Schwartz, EL; Wadler, S1
Alfani, D; Berloco, P; Bruzzone, P; Caricato, M; Casciaro, G; Cortesini, R; Iappelli, M; Marciani, A; Rossi, M; Urbano, D1
Berchtold, CM; Casero, RA; Celano, P; Giardiello, FM1
Fontaine, J; Rapaport, E1
Allan, PW; Bennett, LL; Brockman, RW; Clayton, JD; Rose, LM; Shaddix, SC; Shealy, YF1
Chin, PC; Franklin, CC; Kim, HD; Turner, JT1
Glazer, RI; Haines, DR; Knode, MC; Marquez, VE; Tseng, CK1
Barlogie, B; Dipasquale, MA; Drewinko, B; Trujillo, JM; Yang, LY1

Reviews

3 review(s) available for adenosine and Colonic Neoplasms

ArticleYear
The functions of N6-methyladenosine (m6A) RNA modifications in colorectal cancer.
    Medical oncology (Northwood, London, England), 2022, Sep-29, Volume: 39, Issue:12

    Topics: Adenosine; Colonic Neoplasms; Epigenesis, Genetic; Humans; RNA, Messenger

2022
The Hypoxia-Adenosine Link during Intestinal Inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2018, 02-01, Volume: 200, Issue:3

    Topics: Adenosine; Animals; Cell Hypoxia; Colonic Neoplasms; Epithelial Cells; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Mice; Reperfusion Injury; Tight Junctions

2018
Solid cancers after antiplatelet therapy: Confirmations, controversies, and challenges.
    Thrombosis and haemostasis, 2015, Nov-25, Volume: 114, Issue:6

    Topics: Adenosine; Animals; Anticarcinogenic Agents; Aspirin; Blood Platelets; Carcinogenicity Tests; Clopidogrel; Colonic Neoplasms; Drug Therapy, Combination; Female; Humans; Lactones; Male; Mice; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Neoplastic Cells, Circulating; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Randomized Controlled Trials as Topic; Rivaroxaban; Sex Factors; Species Specificity; Ticagrelor; Ticlopidine; Time Factors

2015

Other Studies

58 other study(ies) available for adenosine and Colonic Neoplasms

ArticleYear
A novel halogenated adenosine analog 5'-BrDA displays potent toxicity against colon cancer cells in vivo and in vitro.
    Toxicology and applied pharmacology, 2022, 02-01, Volume: 436

    Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; HCT116 Cells; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; Reactive Oxygen Species; Signal Transduction

2022
Comprehensive analysis of m
    Gene, 2022, May-05, Volume: 821

    Topics: Adenosine; Algorithms; B7-H1 Antigen; Colonic Neoplasms; Computational Biology; Connectin; Databases, Genetic; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Immunotherapy; Prognosis; Proto-Oncogene Proteins p21(ras); Survival Analysis; Tumor Microenvironment

2022
Abnormal Expression of N6-Methyladenosine RNA Methylation Regulator IGF2BP3 in Colon Cancer Predicts a Poor Prognosis.
    Disease markers, 2022, Volume: 2022

    Topics: Adenocarcinoma; Adenosine; Colonic Neoplasms; Humans; Methylation; Prognosis; RNA; Tumor Microenvironment

2022
A natural halogenated fluoride adenosine analog 5'-fluorodeoxy adenosine induced anticolon cancer activity in vivo and in vitro.
    Environmental toxicology, 2022, Volume: 37, Issue:10

    Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Caspase 8; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Fluorides; Mice

2022
Adenosine dialdehyde, a methyltransferase inhibitor, induces colorectal cancer cells apoptosis by regulating PIMT:p53 interaction.
    Biochemical and biophysical research communications, 2023, 12-03, Volume: 684

    Topics: Adenosine; Apoptosis; bcl-2-Associated X Protein; Colonic Neoplasms; Colorectal Neoplasms; Humans; Methyltransferases; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Tumor Suppressor Protein p53

2023
Screening of m6A gene-related lncRNAs in colon adenocarcinoma and construction of a prognostic prediction model.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:21

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine; Cell Adhesion Molecules; Colonic Neoplasms; Guanylate Kinases; Humans; Prognosis; RNA, Long Noncoding

2023
The Prognostic Value of m6A RNA Methylation Regulators in Colon Adenocarcinoma.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Dec-11, Volume: 25

    Topics: Adenocarcinoma; Adenosine; Adenosine Triphosphatases; Algorithms; Cluster Analysis; Colon; Colonic Neoplasms; Databases, Genetic; Gene Expression Profiling; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Methylation; Methyltransferases; Multivariate Analysis; Prognosis; RNA; RNA Helicases; RNA-Binding Proteins; tRNA Methyltransferases

2019
m
    Molecular cancer, 2019, 12-18, Volume: 18, Issue:1

    Topics: Adenosine; Cell Line, Tumor; Cell Self Renewal; Colonic Neoplasms; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Immunohistochemistry; Methylation; Models, Biological; Neoplastic Stem Cells; Polycomb Repressive Complex 1; Promoter Regions, Genetic; Protein Binding; Receptors, G-Protein-Coupled

2019
The YTH Domain Family of N6-Methyladenosine "Readers" in the Diagnosis and Prognosis of Colonic Adenocarcinoma.
    BioMed research international, 2020, Volume: 2020

    Topics: Adenocarcinoma; Adenosine; Aged; Colonic Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methyltransferases; Middle Aged; Prognosis; Protein Domains; RNA-Binding Proteins; Transcriptome

2020
m6A methyltransferase METTL3 maintains colon cancer tumorigenicity by suppressing SOCS2 to promote cell proliferation.
    Oncology reports, 2020, Volume: 44, Issue:3

    Topics: Adenosine; Aged; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Colectomy; Colon; Colonic Neoplasms; Datasets as Topic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Knockout Techniques; Humans; Male; Methylation; Methyltransferases; Middle Aged; Neoplasm Staging; Receptors, G-Protein-Coupled; RNA Stability; RNA, Messenger; Spheroids, Cellular; Suppressor of Cytokine Signaling Proteins; Tubercidin

2020
RNA N6-methyladenosine demethylase FTO regulates PD-L1 expression in colon cancer cells.
    Biochemical and biophysical research communications, 2020, 09-10, Volume: 530, Issue:1

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; B7-H1 Antigen; Cell Line, Tumor; Colonic Neoplasms; Demethylation; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; RNA, Messenger

2020
RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.
    Journal of experimental & clinical cancer research : CR, 2020, Sep-29, Volume: 39, Issue:1

    Topics: Adenosine; Animals; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Cyclin D1; DNA Replication; Female; HCT116 Cells; Heterografts; Humans; Male; Methylation; Mice; Neovascularization, Pathologic; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; Vascular Endothelial Growth Factor A

2020
m
    Theranostics, 2021, Volume: 11, Issue:5

    Topics: Adenosine; Biomarkers, Tumor; Colonic Neoplasms; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Lymphocytes, Tumor-Infiltrating; Transcriptome; Tumor Microenvironment

2021
Expression and Prognostic Characteristics of m6A RNA Methylation Regulators in Colon Cancer.
    International journal of molecular sciences, 2021, Feb-21, Volume: 22, Issue:4

    Topics: Adenosine; Aged; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Male; Methylation; Phenotype; Prognosis; Proportional Hazards Models; Reproducibility of Results; Risk Factors; RNA, Neoplasm

2021
Identification of m6A-Related Biomarkers Associated with Prognosis of Colorectal Cancer.
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Aug-10, Volume: 27

    Topics: Adenocarcinoma; Adenosine; Biomarkers, Tumor; Colonic Neoplasms; Datasets as Topic; Epigenesis, Genetic; Esophageal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Methylation; Prognosis; Protein Interaction Maps; Rectal Neoplasms; Survival Analysis

2021
An N
    Biochemical pharmacology, 2019, Volume: 160

    Topics: Adenosine; beta Catenin; Cell Line, Tumor; Codon; Colonic Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Methyltransferases; Mutation, Missense; Oxaliplatin; RNA, Messenger; Trihexosylceramides; Tumor Suppressor Protein p53

2019
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.
    Molecular oncology, 2019, Volume: 13, Issue:4

    Topics: Adenocarcinoma; Adenosine; Animals; Bone Marrow Cells; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Culture Media, Conditioned; Dendritic Cells; Epigenesis, Genetic; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Biological; Pancreatic Neoplasms; Phenylurea Compounds; Signal Transduction; Thiostrepton; Wnt-5a Protein

2019
Differential effect of adenosine receptors on growth of human colon cancer HCT 116 and HT-29 cell lines.
    Archives of biochemistry and biophysics, 2013, Volume: 533, Issue:1-2

    Topics: Adenosine; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Space; Fluorouracil; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Protein Phosphatase 2; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Signal Transduction

2013
Adenosine induces apoptosis through TNFR1/RIPK1/P38 axis in colon cancer cells.
    Biochemical and biophysical research communications, 2015, May-08, Volume: 460, Issue:3

    Topics: Adenosine; Apoptosis; Colonic Neoplasms; Humans; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor, Type I

2015
Enhanced efficacy of photodynamic therapy by inhibiting ABCG2 in colon cancers.
    BMC cancer, 2015, Jul-07, Volume: 15

    Topics: Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Colonic Neoplasms; Diketopiperazines; Disease Models, Animal; Gene Expression; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mice; Neoplasm Proteins; Photochemotherapy; RNA, Messenger; Tumor Burden; Xenograft Model Antitumor Assays

2015
Regulatory T Cells from Colon Cancer Patients Inhibit Effector T-cell Migration through an Adenosine-Dependent Mechanism.
    Cancer immunology research, 2016, Volume: 4, Issue:3

    Topics: Adenocarcinoma; Adenosine; Antigens, CD; Apyrase; Cells, Cultured; Coculture Techniques; Colonic Neoplasms; Human Umbilical Vein Endothelial Cells; Humans; T-Lymphocytes, Regulatory; Transendothelial and Transepithelial Migration

2016
The anti-inflammatory and anti-cancer properties of epigallocatechin-3-gallate are mediated by folate cycle disruption, adenosine release and NF-kappaB suppression.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2008, Volume: 57, Issue:10

    Topics: Adenosine; Anticarcinogenic Agents; Antioxidants; Caco-2 Cells; Catechin; Colonic Neoplasms; Folic Acid; Humans; I-kappa B Proteins; Leucovorin; NF-kappa B; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins c-akt; Tumor Necrosis Factor-alpha; Vitamin B Complex

2008
Adenosine suppresses CW2 human colonic cancer growth by inducing apoptosis via A(1) adenosine receptors.
    Cancer letters, 2010, Apr-28, Volume: 290, Issue:2

    Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Enzyme Activation; Humans; Mice; Receptor, Adenosine A1; Reverse Transcriptase Polymerase Chain Reaction; Xenograft Model Antitumor Assays

2010
A study of three polymorphic sites of ADA gene in colon cancer.
    Cancer investigation, 2010, Volume: 28, Issue:10

    Topics: Adenosine; Adenosine Deaminase; Aged; Colonic Neoplasms; Female; Genotype; Humans; Male; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide

2010
Neutrophil transintestinal epithelial migration to CXCR2 ligands is regulated by adenosine.
    Journal of pediatric gastroenterology and nutrition, 2012, Volume: 54, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Adolescent; Adult; CD18 Antigens; Chemokine CXCL1; Chemokine CXCL5; Chemotaxis, Leukocyte; Child; Colonic Neoplasms; Epithelial Cells; Female; Humans; Inflammation Mediators; Inflammatory Bowel Diseases; Interleukin-8; Intestinal Mucosa; Ligands; Male; Neutrophil Infiltration; Neutrophils; Receptors, Interleukin-8B; Young Adult

2012
ABCG2-overexpressing S1-M1-80 cell xenografts in nude mice keep original biochemistry and cell biological properties.
    Chinese journal of cancer, 2012, Volume: 31, Issue:3

    Topics: Adenosine; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Colonic Neoplasms; Diketopiperazines; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitory Concentration 50; KB Cells; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitoxantrone; Neoplasm Proteins; Neoplasm Transplantation; Rhodamine 123; Topotecan

2012
Antiproliferative activity of kinetin riboside on HCT-15 colon cancer cell line.
    Nucleosides, nucleotides & nucleic acids, 2012, Volume: 31, Issue:6

    Topics: Adenosine; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Shape; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Kinetin; Time Factors

2012
Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.
    Journal of cellular physiology, 2013, Volume: 228, Issue:4

    Topics: Adenosine; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenomics; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; HT29 Cells; Humans; MCF-7 Cells; Neoplasm Proteins; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Tretinoin

2013
Microsatellite instability and intratumoural heterogeneity in 100 right-sided sporadic colon carcinomas.
    British journal of cancer, 2002, Aug-12, Volume: 87, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Base Pair Mismatch; Carrier Proteins; Colonic Neoplasms; DNA Repair; DNA-Binding Proteins; Female; Humans; Immunohistochemistry; Male; Microsatellite Repeats; Mutation; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Polymerase Chain Reaction; Proto-Oncogene Proteins

2002
Inhibition of primary colon carcinoma growth and liver metastasis by the A3 adenosine receptor agonist CF101.
    British journal of cancer, 2003, Oct-20, Volume: 89, Issue:8

    Topics: Adenosine; Administration, Oral; Animals; Biological Availability; Carcinoma; Cell Division; Colonic Neoplasms; Disease Models, Animal; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Agonists; Transplantation, Heterologous; Tumor Cells, Cultured

2003
An agonist to the A3 adenosine receptor inhibits colon carcinoma growth in mice via modulation of GSK-3 beta and NF-kappa B.
    Oncogene, 2004, Apr-01, Volume: 23, Issue:14

    Topics: Adenosine; Animals; beta Catenin; Carcinoma; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Cytoskeletal Proteins; Down-Regulation; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Growth Inhibitors; Humans; Indoles; Lithium; Maleimides; Mice; Mice, Nude; NF-kappa B; Proto-Oncogene Proteins c-myc; Purinergic P1 Receptor Agonists; Pyridines; Trans-Activators

2004
CF101, an agonist to the A3 adenosine receptor, enhances the chemotherapeutic effect of 5-fluorouracil in a colon carcinoma murine model.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:1

    Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Antimetabolites, Antineoplastic; Cell Proliferation; Colonic Neoplasms; Colony-Forming Units Assay; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Transplantation, Heterologous; Tumor Cells, Cultured

2005
Methotrexate induced differentiation in colon cancer cells is primarily due to purine deprivation.
    Journal of cellular biochemistry, 2006, Sep-01, Volume: 99, Issue:1

    Topics: Adenocarcinoma; Adenosine; Alkaline Phosphatase; Antimetabolites, Antineoplastic; Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Cyclic AMP; Extracellular Signal-Regulated MAP Kinases; HT29 Cells; Humans; Hypoxanthines; MAP Kinase Kinase Kinases; Methionine; Methotrexate; Phosphatidylinositol 3-Kinases; Polyamines; Purines; Signal Transduction; Tetrahydrofolates; Thymidine

2006
Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway.
    American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:3

    Topics: Adenosine; Colonic Neoplasms; Dipeptidyl Peptidase 4; Down-Regulation; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; RNA, Messenger; Signal Transduction; Vanadates; Vanadium Compounds

2006
Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.
    Molecular pharmacology, 2007, Volume: 72, Issue:2

    Topics: Adenosine; Caffeine; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Extracellular Signal-Regulated MAP Kinases; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Receptor, Adenosine A2B; Receptor, Adenosine A3; Vascular Endothelial Growth Factor A

2007
Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells.
    Gastroenterology, 2007, Volume: 133, Issue:1

    Topics: Adenosine; Aged; Animals; Cell Death; Cell Division; Colonic Neoplasms; Drug Interactions; Epidermal Growth Factor; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Insulin-Like Growth Factor I; Intestinal Polyps; Leptin; Male; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Middle Aged; Mitogens; Polyamines; Promoter Regions, Genetic; S-Adenosylmethionine

2007
Neplanocin A. A cyclopentenyl analog of adenosine with specificity for inhibiting RNA methylation.
    The Journal of biological chemistry, 1984, Nov-10, Volume: 259, Issue:21

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Coformycin; Colonic Neoplasms; DNA Replication; Humans; Kinetics; Methylation; Pentostatin; Protein Biosynthesis; Ribonucleosides; RNA, Ribosomal; Transcription, Genetic

1984
5'-deoxy-5'-methylthioadenosine phosphorylase--II. Role of the enzyme in the metabolism and antineoplastic action of adenine-substituted analogs of 5'-deoxy-5'-methylthioadenosine.
    Biochemical pharmacology, 1983, Jun-15, Volume: 32, Issue:12

    Topics: Adenosine; Antineoplastic Agents; Cell Division; Cell Line; Chromatography, High Pressure Liquid; Colonic Neoplasms; Deoxyadenosines; Humans; Leukemia; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Substrate Specificity; Thionucleosides

1983
Characterization of a defect in the pathway for converting 5'-deoxy-5'-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma.
    The Journal of biological chemistry, 1984, Jun-10, Volume: 259, Issue:11

    Topics: Adenosine; Animals; Cell Line; Colonic Neoplasms; Deoxyadenosines; Humans; Liver; Methionine; Rats; Ribosemonophosphates; Ribulosephosphates; Thioglycosides; Thionucleosides

1984
Effects of 8-azaadenosine and formycin on cell lethality and the synthesis and methylation of nucleic acids in human colon carcinoma cells in culture.
    Biochemical pharmacology, 1982, Oct-15, Volume: 31, Issue:20

    Topics: Adenosine; Antibiotics, Antineoplastic; Cell Survival; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Formycins; Humans; Methylation; Neoplasms, Experimental; RNA, Neoplasm

1982
Inhibition of HGF/SF-induced membrane ruffling and cell motility by transient elevation of cytosolic free Ca2+.
    Experimental cell research, 1995, Volume: 220, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Calcium; Cell Line; Cell Membrane; Cell Movement; Chelating Agents; Colonic Neoplasms; Cytosol; Egtazic Acid; Hepatocyte Growth Factor; Humans; Ionomycin; Kinetics; Microscopy, Electron, Scanning; Time Factors; Tumor Cells, Cultured; Video Recording

1995
Adenosine inhibits the adhesion of anti-CD3-activated killer lymphocytes to adenocarcinoma cells through an A3 receptor.
    Cancer research, 1994, Jul-01, Volume: 54, Issue:13

    Topics: Adenocarcinoma; Adenosine; Animals; Antibodies; CD3 Complex; Cell Adhesion; Colonic Neoplasms; Killer Cells, Natural; Mice; Theobromine; Thioinosine; Tumor Cells, Cultured; Xanthines

1994
Protective effect of taurine on hypoxia and reoxygenation-induced damage of human colon cells (HT 29).
    Advances in experimental medicine and biology, 1996, Volume: 403

    Topics: Adenosine; Aerobiosis; Allopurinol; Cell Hypoxia; Cell Line; Cell Survival; Colon; Colonic Neoplasms; Glucose; Glutathione; Humans; Hypertonic Solutions; Insulin; Mannitol; Organ Preservation Solutions; Potassium Chloride; Procaine; Raffinose; Taurine; Tissue Preservation

1996
The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine.
    Cancer research, 1997, Jul-01, Volume: 57, Issue:13

    Topics: Adenosine; Animals; Coformycin; Colonic Neoplasms; Enzyme Inhibitors; Extracellular Space; Female; Fibrosarcoma; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Microdialysis; Neoplasm Transplantation; Time Factors; Tubercidin; Tumor Cells, Cultured

1997
Apoptosis induced by modified ribonucleosides in human cell culture systems.
    FEBS letters, 1998, Aug-21, Volume: 433, Issue:3

    Topics: Adenosine; Apoptosis; Cells, Cultured; Colonic Neoplasms; Guanosine; HL-60 Cells; Humans; Inosine; Isopentenyladenosine; Kinetics; Lymphocytes; Ribonucleosides; Tumor Cells, Cultured

1998
Adenosine suppresses alpha(4)beta(7) integrin-mediated adhesion of T lymphocytes to colon adenocarcinoma cells.
    Experimental cell research, 2002, May-15, Volume: 276, Issue:1

    Topics: Adenocarcinoma; Adenosine; Animals; Antibodies; Cell Adhesion; Cells, Cultured; Colonic Neoplasms; Fibronectins; Immunosuppressive Agents; Integrin alpha4beta1; Integrins; Lymphocyte Function-Associated Antigen-1; Mice; Mice, Inbred C57BL; Receptors, Fibronectin; Receptors, Lymphocyte Homing; T-Lymphocytes; Tumor Cells, Cultured; Vascular Cell Adhesion Molecule-1

2002
Isolation and characterization of N6-succinyladenosine from human urine.
    Nucleic acids research, 1977, Volume: 4, Issue:3

    Topics: Adenosine; Chemical Phenomena; Chemistry; Colonic Neoplasms; Humans; Hydrogen-Ion Concentration; Hydrolysis; Nucleotidases; Succinates

1977
High-performance liquid chromatographic separation and quantitation of nucleosides in urine and some other biological fluids.
    Clinical chemistry, 1977, Volume: 23, Issue:8

    Topics: Adenosine; Amniotic Fluid; Chromatography, High Pressure Liquid; Colonic Neoplasms; Evaluation Studies as Topic; Female; Guanosine; Humans; Inosine; Nucleosides; Pregnancy; Pseudouridine; Ribonucleosides

1977
Purinergic receptor activation of Cl- secretion in T84 cells.
    The American journal of physiology, 1992, Volume: 262, Issue:1 Pt 1

    Topics: Adenosine; Adenosine Triphosphate; Calcium; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Humans; Nucleotides; Pertussis Toxin; Receptors, Purinergic; Tumor Cells, Cultured; Virulence Factors, Bordetella

1992
A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Jun-15, Volume: 89, Issue:12

    Topics: 2-Chloroadenosine; Adenocarcinoma; Adenosine; Cell Line; Chlorides; Chromosome Deletion; Colonic Neoplasms; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genotype; Humans; Kinetics; Membrane Proteins; Mutation; Pancreatic Neoplasms; Phenotype; Purinergic Antagonists; Xanthines

1992
Stimulation of 5-fluorouracil metabolic activation by interferon-alpha in human colon carcinoma cells.
    Biochemical and biophysical research communications, 1992, Feb-14, Volume: 182, Issue:3

    Topics: Adenosine; Biotransformation; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Kinetics; Radioisotope Dilution Technique; Recombinant Proteins; RNA, Neoplasm; Thymidine; Tritium

1992
Multiple abdominal visceral transplantation: clinical experience of organ preservation by University of Wisconsin (UW) solution.
    Transplantation proceedings, 1991, Volume: 23, Issue:5

    Topics: Adenoma, Bile Duct; Adenosine; Adult; Allopurinol; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Duodenal Neoplasms; Duodenum; Female; Glutathione; Humans; Insulin; Intestine, Small; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Organ Preservation; Organ Preservation Solutions; Pancreas Transplantation; Pancreatic Neoplasms; Raffinose; Solutions

1991
Modulation of growth gene expression by selective alteration of polyamines in human colon carcinoma cells.
    Biochemical and biophysical research communications, 1989, Nov-30, Volume: 165, Issue:1

    Topics: Adenosine; Blotting, Northern; Cell Division; Cell Line; Colonic Neoplasms; Eflornithine; Gene Expression Regulation, Neoplastic; Humans; Polyamines; Proto-Oncogenes; Putrescine; RNA, Messenger; Spermidine; Spermine; Transcription, Genetic; Tumor Cells, Cultured

1989
Anticancer activities of adenine nucleotides in mice are mediated through expansion of erythrocyte ATP pools.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:5

    Topics: Adenocarcinoma; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Colonic Neoplasms; Erythrocytes; Mice; Weight Loss

1989
Inhibition of utilization of hypoxanthine and guanine in cells treated with the carbocyclic analog of adenosine. Phosphates of carbocyclic nucleoside analogs as inhibitors of hypoxanthine (guanine) phosphoribosyltransferase.
    Molecular pharmacology, 1985, Volume: 27, Issue:6

    Topics: Adenosine; Animals; Carcinoma, Squamous Cell; Cell Line; Coformycin; Colonic Neoplasms; Cyclic GMP; Cyclic IMP; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Nucleotides; Kinetics; Leukemia L1210; Mice; Pentosyltransferases; Ribonucleotides

1985
Insulin regulation of glucose metabolism in HT29 colonic adenocarcinoma cells: activation of glycolysis without augmentation of glucose transport.
    Biochimica et biophysica acta, 1988, Oct-28, Volume: 972, Issue:1

    Topics: 3-O-Methylglucose; Adenocarcinoma; Adenosine; Adenosine Triphosphate; Biological Transport; Colonic Neoplasms; Cytochalasin B; Epithelium; Glucose; Glycolysis; Hexoses; Insulin; Insulin-Like Growth Factor I; Methylglucosides; Monosaccharide Transport Proteins; Tumor Cells, Cultured

1988
3-Deazaneplanocin A: a new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Colonic Neoplasms; Humans; Hydrolases; Kinetics; Methionine; Methylation; RNA, Ribosomal; RNA, Transfer; S-Adenosylhomocysteine; Uridine

1986
The synergistic lethal interaction of cis-diamminedichloroplatinum and natural nucleosides is related to increased DNA cross-links.
    Chemico-biological interactions, 1985, Volume: 55, Issue:1-2

    Topics: Adenosine; Carcinoma; Cell Line; Cell Survival; Cisplatin; Colonic Neoplasms; Cytidine; DNA; Drug Synergism; Humans; Nucleosides; Thymidine; Uridine

1985