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adenosine and Cirrhosis

adenosine has been researched along with Cirrhosis in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.52)18.7374
1990's5 (7.58)18.2507
2000's9 (13.64)29.6817
2010's36 (54.55)24.3611
2020's15 (22.73)2.80

Authors

AuthorsStudies
Jiang, M; Shen, L; Yu, Y; Zhao, J1
Biros, E; Dlaska, C; Dobson, GP; Hazratwala, K; Letson, HL; McEwen, P; Morris, JL; Wilkinson, M1
Dai, J; Hong, Y; Hu, Y; Jiang, P; Li, R; Liu, D; Lv, H; Song, M; Wang, H; Wang, Z; Yao, S; Zhang, X; Zhao, G; Zhou, Z1
Jia, Q; Li, Y; Mehmood, S; Yang, R1
Catarinicchia, S; Jacobson, KA; Lucarini, L; Marri, S; Masini, E; Pini, A; Salvemini, D; Sgambellone, S; Tosh, DK1
Geng, Z; Han, C; Huang, H; Li, W; Li, Z; Liu, R; Pan, X; Wang, Y; Zhang, Y; Zhao, Z; Zuo, X1
Cash, E; Goodwin, AT; Tatler, AL1
de Sánchez, VC; de Vaca, RP; Domínguez-López, M; Guerrero-Celis, N; Rodríguez-Aguilera, JR; Velasco-Loyden, G1
Chen, Z; Liu, X; Yang, C; Yu, H1
Chen, X; Chen, Z; Du, Y; He, Y; Liu, P; Liu, Y; Zhang, B1
Alarcón, S; Cappelli, C; Flores, C; Jara, C; Mendoza, P; Oyarzún, C; Podestá, L; Quezada, C; San Martín, R; Tellez, A; Torres, A1
Onuora, S1
Fan, X; Li, X; Liu, H; Yang, Y; Yin, X1
Jiang, J; Lacefield, JC; McAlister, V; Quan, D; Skaro, AI; Su, Y; Wang, Y; Xue, P; Zheng, H; Zheng, X; Zhu, C1
Aquaro, GD; Arendt, CT; Barison, A; Emdin, M; Grigoratos, C; Gueli, I; Leithner, D; Meloni, A; Nagel, E; Novo, G; Nugara, C; Pepe, A; Puntmann, VO; Todiere, G1
Gao, X; Wu, Y; Xu, Y; Zhan, S1
Alter, C; Borg, N; Ding, Z; Quast, C; Schrader, J1
Arany, ZP; Ibrahim, A; Neinast, M1
Dai, Y; Lei, J; Li, M; Tang, J; Xia, B; Xia, Y; Yin, G; Zhou, Y1
Bian, BL; Li, JR; Peng, B; Si, N; Sun, W; Wang, HJ; Yang, J; Zhao, HY1
Arheden, H; Carlsson, M; Engblom, H; Gyllenhammar, T; Hesselstrand, R; Kanski, M; Wuttge, DM1
Aburatani, H; Hirakawa, Y; Kanki, Y; Mimura, I; Nakaki, R; Nangaku, M; Suzuki, Y; Tanaka, T1
Ha, H; Jarhad, DB; Jeong, LS; Kim, G; Lee, HW; Lee, J; Park, CW; Yu, J1
Hirano, K; Igarashi, J; Karita, S; Kubota, Y; Nakai, K; Tsukamoto, I1
Gao, R; Ge, W; Li, B; Wang, J; Zhang, W; Zhu, H1
Chen, X; Li, P; Liu, W; Meng, G; Shen, HY; Si, LY; Xiao, H; Xiong, RP; Yang, N; Zhou, YG1
Bujor, AM; Chan, ES; Cronstein, BN; Fernandez, P; Liu, H; Luna, A; Perez-Aso, M; Trojanowska, M1
Insel, PA; Lu, D2
Daryoni, E; Mattson-Hultén, L; Omerovic, E; Redfors, B; Said, M; Scharing Täng, M; Shao, Y1
Ha, H; Hwang, I; Jeong, LS; Lee, HW; Lee, J; Lee, JH1
Chan, ESL; Chiriboga, L; Cronstein, BN; Fernández, P; Franks, A; Perez-Aso, M; Robson, SC; Smith, G; Trzaska, S; Wilder, T1
Allain, G; Billault, C; Couturier, P; Delpech, PO; Giraud, S; Hauet, T; Marchand, E; Parkkinen, J; Saintyves, T; Thuillier, R; Vaahtera, L1
Biesiadecki, BJ; Billman, GE; Carnes, CA; Csepe, TA; Fedorenko, O; Fedorov, VV; Glukhov, AV; Györke, S; Hage, LT; Hansen, BJ; Kalyanasundaram, A; Li, N; Lou, Q; Mohler, PJ; Weiss, R1
Alexander, SI; Cowan, PJ; Dwyer, KM; Roberts, VS; Robson, SC1
Haïssaguerre, M; Hocini, M; Jaïs, P; Shah, AJ; Weerasooriya, R1
Ashrafian, H; Dass, S; Ferreira, VM; Francis, JM; Karamitsos, TD; Levelt, E; Lewis, A; Mahmod, M; Neubauer, S; Pal, N; Piechnik, SK1
Birnbaum, GD; Birnbaum, Y; Nanhwan, MK; Nylander, S; Perez-Polo, JR; Ye, Y1
Bangalore, S; De Pasquale, CG; Gleadle, JM; Grover, S; Parnham, S; Perry, R; Selvanayagam, JB; Woodman, RJ1
Albanesi, C; Cronstein, B; Ferrari, D; Gambari, R; Idzko, M; La Manna, G; Müller, T; Pastore, S; Robson, SC1
Böhm, M; Devaux, Y; Fries, P; Kazakov, A; Maack, C; Müller, A; Puhl, SL; Wagner, DR1
Alarcón, S; Díaz-Encarnación, MM; Garrido, W; Jaramillo, C; Kretschmar, C; Oyarzún, C; Pastor-Anglada, M; Perez, G; Quezada, C; San Martín, R; Villablanca, C1
Chepurko, E; Covarrubias, R; Feoktistov, I; Gumina, RJ; Novitskaya, T; Novitskiy, S; Ryzhov, SV1
Baltos, JA; Christopoulos, A; Chuo, CH; Ford, L; May, LT; Scammells, PJ; Vecchio, EA; Wang, BH; White, PJ1
Cronstein, BN; Sitkovsky, M1
Chan, ES; Chiriboga, L; Cronstein, BN; Fernandez, P; Peng, Z; Wilder, T; Yee, H1
Chaimovitz, C; Douvdevani, A; Kachko, L; Nakav, S; Rogachev, B; Vorobiov, M; Zlotnik, M1
Blackburn, MR; Dai, Y; Mi, T; Phatarpekar, P; Xia, Y; Zhang, H; Zhang, Y1
Biaggioni, I; Cronstein, BN; Feoktistov, I1
Blackburn, MR; Dai, Y; Jiang, X; Kellems, RE; Mi, T; Phatarpekar, PV; Sun, H; Tang, Y; Wen, J; Xia, Y; Zhang, Y1
Chan, ES; Cronstein, BN1
Cau, J; Favreau, F; Hauet, T; Lerman, LO; Manguy, E; Mauco, G; Milin, S; Thuillier, R; Zhu, X1
Arcelus, S; Avila, MA; Banales, JM; Berasain, C; Corrales, FJ; Fernández-Barrena, MG; Gil-Puig, C; Goñi, S; Juanarena, N; Latasa, MU; Lecanda, J; Lotersztajn, S; Méndez, M; Prieto, J; Recio, JA; Rodríguez-Ortigosa, CM; Urtasun, R1
Chen, JF; Feng, L; Garcia, GE; Johnson, RJ; Truong, LD1
Arce, Y; Ballarín, JA; Choi, DS; Díaz-Encarnación, MM; Guillén-Gómez, E; Pastor-Anglada, M; Pérez-Torras, S; Pinilla-Macua, I1
Blackburn, MR; Thompson, LF; Volmer, JB1
Blackburn, MR; Boyden, L; Elias, JA; Flavell, RA; Homer, RJ; Lee, CG; Lifton, RP; Liu, W; Ma, B; Sun, CX; Young, HW1
Abbasi, S; Blackburn, MR; Chunn, JL; Kellems, RE; Mi, T; Molina, JG; Uray, K; Weisbrodt, NW; Xia, LW; Xia, Y; Zhang, H1
Bache, RJ; Chen, Y; Fassett, J; Hu, X; Li, Y; Lu, Z; Schnermann, J; Xu, X; Zhu, G1
Blackburn, MR; Chan, ES; Chiriboga, L; Cronstein, BN; Fernández, P; Trzaska, S; Wilder, T1
Jacobs, MJ; Klopper, PJ; Kromhout, JG; Pfaffendorf, M; Van Gulik, TM; Van Marle, J; Van Zwieten, PA; Vischjager, M1
Hirst, K; Langnas, AN; Markin, RS; Radio, SJ; Shaw, BW; Stratta, RJ; Wisecarver, JL1
Dubey, RK; Gillespie, DG; Jackson, EK1
Fielding, P; Freemont, AJ; Hoyland, J; Jones, CJ; Prescott, RJ1
Chagoya de Sánchez, V; Díaz-Muñoz, M; Hernández-Muñoz, R; Suárez, J1
Bishop, SP; Gelpi, RJ; Hittinger, L; Shannon, RP; Vatner, SF1

Reviews

13 review(s) available for adenosine and Cirrhosis

ArticleYear
Adenosine receptor signalling as a driver of pulmonary fibrosis.
    Pharmacology & therapeutics, 2023, Volume: 249

    Topics: Adenosine; Fibroblasts; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Lung; Receptors, Purinergic P1

2023
RNA modifications in cardiovascular diseases, the potential therapeutic targets.
    Life sciences, 2021, Aug-01, Volume: 278

    Topics: Adenosine; Animals; Atherosclerosis; Cardiovascular Diseases; Coronary Disease; Epigenesis, Genetic; Fibrosis; Gene Expression Profiling; Gene Expression Regulation; Heart Failure; Humans; Hypertension, Pulmonary; Hypertrophy; Metabolic Syndrome; Methylation; Mice; Microcirculation; Myocardium; Regeneration; Reperfusion Injury; RNA; RNA Processing, Post-Transcriptional; RNA, Untranslated; Transcriptome

2021
Myobolites: muscle-derived metabolites with paracrine and systemic effects.
    Current opinion in pharmacology, 2017, Volume: 34

    Topics: Adenosine; Adipocytes; Aminoisobutyric Acids; Animals; Cardiomegaly; Cyclic AMP; Fatty Acids; Fibrosis; Humans; Liver; Muscle, Skeletal; Myocardium; Vasodilation

2017
Cellular mechanisms of tissue fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosis.
    American journal of physiology. Cell physiology, 2014, May-01, Volume: 306, Issue:9

    Topics: Adenosine; Adenosine Triphosphate; Animals; Autocrine Communication; Cell Transdifferentiation; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Myofibroblasts; Paracrine Communication; Phenotype; Purines; Receptors, Purinergic; Receptors, Purinergic P2X; Receptors, Purinergic P2Y; Signal Transduction

2014
The role of adenosine receptors A2A and A2B signaling in renal fibrosis.
    Kidney international, 2014, Volume: 86, Issue:4

    Topics: Adenosine; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Autocrine Communication; Fibroblasts; Fibrosis; Humans; Kidney; Macrophages; Paracrine Communication; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Renal Insufficiency, Chronic; Signal Transduction

2014
Contemporary challenges of catheter ablation for atrial fibrillation.
    Clinical therapeutics, 2014, Sep-01, Volume: 36, Issue:9

    Topics: Adenosine; Atrial Fibrillation; Catheter Ablation; Electrophysiologic Techniques, Cardiac; Fibrosis; Heart Atria; Humans; Patient Selection; Pulmonary Veins; Treatment Outcome

2014
Purinergic signaling in scarring.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:1

    Topics: Adenosine; Animals; Fibrosis; Humans; Liver; Purinergic Agents; Signal Transduction; Uridine Triphosphate

2016
Extracellular nucleotide regulation and signaling in cardiac fibrosis.
    Journal of molecular and cellular cardiology, 2016, Volume: 93

    Topics: Adenosine; Animals; Extracellular Space; Fibrosis; Humans; Hydrolysis; Myocardium; Nucleotides; Receptors, Purinergic; Signal Transduction

2016
Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases.
    Nature reviews. Rheumatology, 2017, Volume: 13, Issue:1

    Topics: Adaptive Immunity; Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Fibrosis; Gene Dosage; Humans; Immunity, Innate; Inflammation; Receptor, Adenosine A2A; Receptors, Purinergic P1; Rheumatic Diseases; T-Lymphocytes

2017
Ecto-5'-nucleotidase (CD73)-mediated extracellular adenosine production plays a critical role in hepatic fibrosis.
    Nucleosides, nucleotides & nucleic acids, 2008, Volume: 27, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Animals; Extracellular Space; Fibrosis; Humans; Liver

2008
Adenosine signaling, priapism and novel therapies.
    The journal of sexual medicine, 2009, Volume: 6 Suppl 3

    Topics: Adenosine; Adenosine Deaminase; Animals; Endothelium, Vascular; Fibrosis; Male; Mice; Muscle, Smooth; Penis; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Priapism; Signal Transduction

2009
Adenosine receptors in wound healing, fibrosis and angiogenesis.
    Handbook of experimental pharmacology, 2009, Issue:193

    Topics: Adenosine; Animals; Collagen; Fibrosis; Humans; Neovascularization, Physiologic; Receptors, Purinergic P1; Wound Healing

2009
Adenosine in fibrosis.
    Modern rheumatology, 2010, Volume: 20, Issue:2

    Topics: Adenosine; Animals; Fibrosis; Humans; Mice; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Signal Transduction; Wound Healing

2010

Other Studies

53 other study(ies) available for adenosine and Cirrhosis

ArticleYear
Alteration of the m
    Epigenomics, 2021, Volume: 13, Issue:23

    Topics: Adenosine; Animals; Autoimmune Diseases; Bleomycin; Connective Tissue Diseases; Disease Models, Animal; Female; Fibrosis; Gene Expression; Methylation; Mice, Inbred BALB C; RNA, Messenger; Skin

2021
Comparison of intra-articular administration of adenosine, lidocaine and magnesium solution and tranexamic acid for alleviating postoperative inflammation and joint fibrosis in an experimental model of knee arthroplasty.
    Journal of orthopaedic surgery and research, 2021, Dec-20, Volume: 16, Issue:1

    Topics: Adenosine; Administration, Intravenous; Animals; Antifibrinolytic Agents; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Fibrosis; Inflammation; Injections, Intra-Articular; Interleukin-10; Interleukin-12; Lidocaine; Magnesium; Male; Models, Theoretical; Osteoarthritis, Knee; Postoperative Hemorrhage; Rats; Rats, Sprague-Dawley; Tranexamic Acid

2021
Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions.
    Autophagy, 2022, Volume: 18, Issue:10

    Topics: Actins; Adenosine; AMP-Activated Protein Kinases; Animals; Autophagy; Cadherins; Cathepsin D; Chloroquine; Endometrium; Epithelial-Mesenchymal Transition; Female; Fibronectins; Fibrosis; Iodide Peroxidase; Lipopolysaccharides; Lysosomal-Associated Membrane Protein 1; Mice; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Phosphates; Proto-Oncogene Proteins c-akt; Sequestosome-1 Protein; Serine; Sirolimus; TOR Serine-Threonine Kinases; Transforming Growth Factor beta; Triiodothyronine

2022
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.
    Experimental biology and medicine (Maywood, N.J.), 2022, Volume: 247, Issue:17

    Topics: Adenosine; AMP-Activated Protein Kinases; Animals; Autophagy; Beclin-1; Blood Glucose; Catechin; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Fibrosis; Hydroxyproline; Hypertrophy; Mammals; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microtubule-Associated Proteins; Rats; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1

2022
Adenosine A
    International journal of molecular sciences, 2022, Nov-01, Volume: 23, Issue:21

    Topics: Adenosine; Animals; Bleomycin; Fibroblasts; Fibrosis; Inflammation; Lung; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Receptors, Purinergic P1; Transforming Growth Factor beta

2022
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
    Journal of the science of food and agriculture, 2023, Volume: 103, Issue:15

    Topics: Adenosine; AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Fibrosis; Gastrointestinal Microbiome; Inflammation; Lipid Metabolism; Lipopolysaccharides; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Polysaccharides

2023
Liver fibrotic development is reduced through inflammation prevention by an adenosine derivative compound.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Adenosine; Animals; Carbon Tetrachloride; Cytokines; Fibrosis; Inflammation; Liver; Liver Cirrhosis; Male; Rats; Rats, Wistar

2023
Inhibition of Disruptor of Telomeric Silencing 1-Like Alleviated Renal Ischemia and Reperfusion Injury-Induced Fibrosis by Blocking PI3K/AKT-Mediated Oxidative Stress.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Adenosine; Animals; Cells, Cultured; Disease Models, Animal; Fibrosis; Histone-Lysine N-Methyltransferase; Humans; Male; Oxidative Stress; Phenylurea Compounds; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2019
m
    Aging, 2020, 03-23, Volume: 12, Issue:6

    Topics: Adenosine; Animals; Down-Regulation; Epithelial-Mesenchymal Transition; Fibrosis; Focal Adhesion Protein-Tyrosine Kinases; Humans; Kidney; Kidney Diseases; Male; Methyltransferases; Mice; MicroRNAs; RNA, Long Noncoding; Signal Transduction; Transforming Growth Factor beta1

2020
The TGF-β profibrotic cascade targets ecto-5'-nucleotidase gene in proximal tubule epithelial cells and is a traceable marker of progressive diabetic kidney disease.
    Biochimica et biophysica acta. Molecular basis of disease, 2020, 07-01, Volume: 1866, Issue:7

    Topics: 5'-Nucleotidase; Adenosine; Biomarkers; Cell Line; Diabetic Nephropathies; E1A-Associated p300 Protein; Epigenesis, Genetic; Epithelial Cells; Fibrosis; Gene Expression Regulation; GPI-Linked Proteins; Humans; Kidney; Kidney Tubules, Proximal; Nucleotidases; Promoter Regions, Genetic; RNA Polymerase II; Transforming Growth Factor beta

2020
Targeting adenosine in SSc.
    Nature reviews. Rheumatology, 2020, Volume: 16, Issue:6

    Topics: Adenosine; Adenosine Deaminase; Fibrosis; Humans; Inflammation; Scleroderma, Systemic; Vascular Diseases

2020
Alteration of N
    Epigenomics, 2020, Volume: 12, Issue:14

    Topics: Adenosine; Animals; Blood Urea Nitrogen; Creatinine; Epigenesis, Genetic; Fibrosis; Kidney; Kidney Diseases; Mice; Mice, Inbred C57BL; RNA, Messenger; Signal Transduction; Transcriptome; Ureteral Obstruction

2020
An Addition of U0126 Protecting Heart Grafts From Prolonged Cold Ischemia-Reperfusion Injury in Heart Transplantation: A New Preservation Strategy.
    Transplantation, 2021, 02-01, Volume: 105, Issue:2

    Topics: Adenosine; Allopurinol; Animals; Apoptosis; Butadienes; Cell Hypoxia; Cell Line; Cold Ischemia; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Glutathione; Heart Transplantation; Insulin; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitriles; Organ Preservation; Organ Preservation Solutions; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Raffinose; Rats; Signal Transduction; Ventricular Function, Left

2021
Prevalence and prognostic impact of nonischemic late gadolinium enhancement in stress cardiac magnetic resonance.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2020, Volume: 21, Issue:12

    Topics: Adenosine; Aged; Contrast Media; Dipyridamole; Female; Fibrosis; Heart Diseases; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Myocardium; Perfusion Imaging; Predictive Value of Tests; Prevalence; Prognosis; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Vasodilator Agents

2020
Adenosine Formed by CD73 on T Cells Inhibits Cardiac Inflammation and Fibrosis and Preserves Contractile Function in Transverse Aortic Constriction-Induced Heart Failure.
    Circulation. Heart failure, 2017, Volume: 10, Issue:4

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Aorta; Collagen; Constriction; Disease Models, Animal; Fibrosis; Heart Failure; Inflammation; Interleukin-3; Male; Mice; Mice, Knockout; Signal Transduction; T-Lymphocytes

2017
Acute rejection after kidney transplantation promotes graft fibrosis with elevated adenosine level in rat.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Acute Disease; Adenosine; Allografts; Animals; Collagen; Fibrosis; Graft Rejection; Isografts; Kidney; Kidney Transplantation; Rats; Rats, Sprague-Dawley; Rats, Wistar

2017
[Study on characteristic spectrum of ingredients from different species Cordyceps and its anti-fibrotic activity on human embryonic fibroblasts].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, Volume: 41, Issue:14

    Topics: Adenosine; Cells, Cultured; Cordyceps; Deoxyadenosines; Fibroblasts; Fibrosis; Humans; Transforming Growth Factor beta1; Uridine

2016
Decreased global myocardial perfusion at adenosine stress as a potential new biomarker for microvascular disease in systemic sclerosis: a magnetic resonance study.
    BMC cardiovascular disorders, 2018, 01-30, Volume: 18, Issue:1

    Topics: Adenosine; Adult; Aged; Aged, 80 and over; Case-Control Studies; Coronary Circulation; Cross-Sectional Studies; Female; Fibrosis; Heart Diseases; Humans; Magnetic Resonance Imaging, Cine; Male; Microcirculation; Middle Aged; Myocardial Perfusion Imaging; Myocardium; Predictive Value of Tests; Scleroderma, Systemic; Vasodilator Agents; Ventricular Remodeling

2018
Genome-wide analysis revealed that DZNep reduces tubulointerstitial fibrosis via down-regulation of pro-fibrotic genes.
    Scientific reports, 2018, 02-28, Volume: 8, Issue:1

    Topics: Adenosine; Animals; Biomarkers; Cells, Cultured; Fibrosis; Gene Expression Profiling; Gene Expression Regulation; Genome; Humans; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Reperfusion Injury

2018
Correlation study between A
    Archives of pharmacal research, 2019, Volume: 42, Issue:9

    Topics: Adenosine; Adenosine A3 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Fibrosis; Humans; Kidney Diseases; Molecular Structure; Rats; Receptor, Adenosine A3; Structure-Activity Relationship

2019
COA-Cl prevented TGF-β1-induced CTGF expression by Akt dephosphorylation in normal human dermal fibroblasts, and it attenuated skin fibrosis in mice models of systemic sclerosis.
    Journal of dermatological science, 2019, Volume: 94, Issue:1

    Topics: Adenosine; Angiotensin II; Animals; Cell Line; Connective Tissue Growth Factor; Disease Models, Animal; Drug Evaluation, Preclinical; Fibroblasts; Fibrosis; Humans; Male; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt; Scleroderma, Systemic; Skin; Transforming Growth Factor beta1

2019
IMM-H007 improves heart function via reducing cardiac fibrosis.
    European journal of pharmacology, 2019, Aug-15, Volume: 857

    Topics: Adenosine; AMP-Activated Protein Kinases; Angiotensin II; Animals; Collagen; Fibroblasts; Fibrosis; Gene Expression Regulation; Heart; Humans; Male; Mice; Mice, Inbred C57BL; Myocardium; Myofibroblasts; Phosphorylation; Smad2 Protein; Transforming Growth Factor beta1

2019
Adenosine A2A receptor: a target for regulating renal interstitial fibrosis in obstructive nephropathy.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Biomarkers; CD4-Positive T-Lymphocytes; Cell Movement; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibrosis; Gene Expression; Humans; Kidney; Mice; Mice, Knockout; Nephritis; Phenethylamines; Receptor, Adenosine A2A; rho-Associated Kinases; Transforming Growth Factor beta1; Ureteral Obstruction

2013
Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.
    Arthritis research & therapy, 2013, Volume: 15, Issue:3

    Topics: Adenosine; Blotting, Western; Cell Line; Collagen; Connective Tissue Growth Factor; Fibroblasts; Fibrosis; Humans; Proto-Oncogene Protein c-fli-1; Real-Time Polymerase Chain Reaction; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; Scleroderma, Localized; Skin

2013
Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts.
    The Journal of biological chemistry, 2013, Jun-28, Volume: 288, Issue:26

    Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Collagen; Fibroblasts; Fibrosis; Gene Knockdown Techniques; Homeostasis; Hydrolysis; Male; Myocardium; Phenotype; Phosphorylation; Protein Isoforms; Rats; Rats, Sprague-Dawley; Signal Transduction

2013
Adenosine prevents isoprenaline-induced cardiac contractile and electrophysiological dysfunction.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Adenosine; Animals; Biomarkers; Electrophysiological Phenomena; Fibrosis; Heart; Isoproterenol; Lipids; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Myocardium; Oxidative Stress; Transcriptome

2013
The selective A3AR antagonist LJ-1888 ameliorates UUO-induced tubulointerstitial fibrosis.
    The American journal of pathology, 2013, Volume: 183, Issue:5

    Topics: Adenosine; Adenosine A3 Receptor Antagonists; Animals; Collagen Type I; Epithelial-Mesenchymal Transition; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; Fibronectins; Fibrosis; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Protein-Lysine 6-Oxidase; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; RNA, Messenger; Signal Transduction; Smad Proteins; Thiophenes; Transforming Growth Factor beta1; Ureteral Obstruction

2013
Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.
    The American journal of pathology, 2013, Volume: 183, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Animals; Antibiotics, Antineoplastic; Antigens, CD; Apyrase; Bleomycin; Dermis; Fibrosis; Mice; Mice, Knockout; Scleroderma, Systemic; Transforming Growth Factor beta1

2013
Cyclodextrin curcumin formulation improves outcome in a preclinical pig model of marginal kidney transplantation.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2014, Volume: 14, Issue:5

    Topics: Adenosine; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cells, Cultured; Chemistry, Pharmaceutical; Curcumin; Cyclodextrins; Disease Models, Animal; Fibrosis; Flow Cytometry; Glutathione; Graft Rejection; Humans; Inflammation; Insulin; Kidney Transplantation; Kidney Tubules; Male; Organ Preservation Solutions; Oxidative Stress; Prostate; Raffinose; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine

2014
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.
    Circulation, 2014, Jul-22, Volume: 130, Issue:4

    Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Atrial Fibrillation; Bradycardia; Cardiac Pacing, Artificial; Dogs; Dose-Response Relationship, Drug; Fibrosis; Heart Conduction System; Heart Failure; Receptor, Adenosine A1; Sinoatrial Node; Tachycardia; Theophylline; Up-Regulation; Voltage-Sensitive Dye Imaging; Xanthines

2014
Adenosine stress native T1 mapping in severe aortic stenosis: evidence for a role of the intravascular compartment on myocardial T1 values.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2014, Nov-20, Volume: 16

    Topics: Adenosine; Aged; Aortic Valve; Aortic Valve Stenosis; Case-Control Studies; Contrast Media; Coronary Circulation; Female; Fibrosis; Gadolinium DTPA; Heart Valve Prosthesis Implantation; Humans; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Contraction; Myocardial Perfusion Imaging; Myocardium; Predictive Value of Tests; Prospective Studies; Severity of Illness Index; Treatment Outcome; Vasodilation; Vasodilator Agents; Ventricular Function, Left

2014
Ticagrelor protects the heart against reperfusion injury and improves remodeling after myocardial infarction.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:8

    Topics: Adenosine; Administration, Oral; Animals; Apoptosis; Cardiotonic Agents; Clopidogrel; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Injections, Intraperitoneal; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Purinergic P2Y Receptor Antagonists; Rats, Sprague-Dawley; Signal Transduction; Ticagrelor; Ticlopidine; Time Factors; Ventricular Function, Left; Ventricular Remodeling

2015
Impaired Myocardial Oxygenation Response to Stress in Patients With Chronic Kidney Disease.
    Journal of the American Heart Association, 2015, Aug-10, Volume: 4, Issue:8

    Topics: Adenosine; Adult; Aged; Biomarkers; Case-Control Studies; Contrast Media; Female; Fibrosis; Glomerular Filtration Rate; Heart Diseases; Humans; Kidney; Kidney Transplantation; Linear Models; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardium; Organometallic Compounds; Oxygen; Oxygen Consumption; Predictive Value of Tests; Renal Insufficiency, Chronic; Vasodilator Agents

2015
Adenosine A1 receptor activation attenuates cardiac hypertrophy and fibrosis in response to α1 -adrenoceptor stimulation in vivo.
    British journal of pharmacology, 2016, Volume: 173, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adrenergic alpha-1 Receptor Agonists; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cell Culture Techniques; Dose-Response Relationship, Drug; Fibrosis; Insulin-Like Growth Factor I; Male; Matrix Metalloproteinase 2; Mice; Myocytes, Cardiac; Oxidative Stress; Phenylephrine; Rats; Receptor, Adenosine A1; Up-Regulation

2016
Reduced Adenosine Uptake and Its Contribution to Signaling that Mediates Profibrotic Activation in Renal Tubular Epithelial Cells: Implication in Diabetic Nephropathy.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Adenosine; Animals; Cell Line; Diabetic Nephropathies; Epithelial Cells; Fibrosis; Humans; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley; Signal Transduction

2016
The hybrid molecule, VCP746, is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling.
    Biochemical pharmacology, 2016, Oct-01, Volume: 117

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Allosteric Regulation; Animals; Animals, Newborn; Binding, Competitive; Cell Line; Cells, Cultured; CHO Cells; Collagen; Cricetulus; Fibrosis; Humans; Ligands; Mesangial Cells; Myoblasts, Cardiac; Protective Agents; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Recombinant Proteins; Signal Transduction; Thiophenes

2016
Blocking adenosine A2A receptor reduces peritoneal fibrosis in two independent experimental models.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:8

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cells, Cultured; Central Nervous System Stimulants; Chlorhexidine; Collagen; Disease Models, Animal; Fibroblasts; Fibrosis; Mice; Mice, Knockout; Peritoneal Cavity; Phenethylamines; Vasodilator Agents

2009
Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Volume: 24, Issue:3

    Topics: Actins; Adenosine; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Fibrosis; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Penis; Priapism; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta1

2010
Anti-thrombin therapy during warm ischemia and cold preservation prevents chronic kidney graft fibrosis in a DCD model.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2010, Volume: 10, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Anticoagulants; Azetidines; Base Sequence; Benzylamines; Chronic Disease; DNA Primers; Fibrosis; Glutathione; Humans; Insulin; Kidney; Kidney Transplantation; Male; Models, Animal; Organ Preservation; Organ Preservation Solutions; Oxidative Stress; Plasminogen Activator Inhibitor 1; Raffinose; RNA, Messenger; Signal Transduction; Swine; Temperature; Tissue Donors; Tissue Plasminogen Activator; Transforming Growth Factor beta; Transplantation, Autologous

2010
Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice.
    PloS one, 2010, Dec-29, Volume: 5, Issue:12

    Topics: Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cyclin D1; Cytokines; Disease Progression; Fibroblasts; Fibrosis; Inflammation; Liver; Liver Diseases; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-jun; Thionucleosides

2010
Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation.
    Kidney international, 2011, Volume: 80, Issue:4

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Anti-Inflammatory Agents; Autoantibodies; Disease Models, Animal; Extracellular Matrix Proteins; Fibrosis; Glomerulonephritis; Inflammation Mediators; Kidney; Macrophages; Male; Phenethylamines; Rats; Rats, Inbred WKY; Receptor, Adenosine A2A; Severity of Illness Index; Time Factors; Triazines; Triazoles

2011
New role of the human equilibrative nucleoside transporter 1 (hENT1) in epithelial-to-mesenchymal transition in renal tubular cells.
    Journal of cellular physiology, 2012, Volume: 227, Issue:4

    Topics: Adenosine; Animals; Base Sequence; Cell Line; Collagen; Epithelial-Mesenchymal Transition; Equilibrative Nucleoside Transporter 1; Fibrosis; Gene Expression; Gene Knockdown Techniques; Humans; Kidney Tubules, Proximal; Mice; Mice, Knockout; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta1

2012
Ecto-5'-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Apr-01, Volume: 176, Issue:7

    Topics: 5'-Nucleotidase; Adenosine; Animals; Bleomycin; Collagen; Fibrosis; Inflammation; Lung Diseases; Mice; Models, Animal; Nucleotidases

2006
Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis.
    The Journal of clinical investigation, 2006, Volume: 116, Issue:5

    Topics: Adenosine; Animals; Emphysema; Female; Fibrosis; Inflammation; Interleukin-4; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pulmonary Alveoli; Rats; Species Specificity; Transforming Growth Factor beta; Transforming Growth Factor beta1

2006
Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling.
    The Journal of clinical investigation, 2008, Volume: 118, Issue:4

    Topics: Adenosine; Adenosine Deaminase; Animals; Cyclic AMP; Cyclic GMP; Fibrosis; Male; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Penile Erection; Penis; Receptor, Adenosine A2B; Signal Transduction; Time Factors

2008
Ecto-5'-nucleotidase deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Animals; Blood Pressure; Cell Division; Cells, Cultured; Collagen; Fibroblasts; Fibrosis; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Mice; Mice, Knockout; Myocytes, Cardiac; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases; Ventricular Dysfunction, Left

2008
Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine.
    The American journal of pathology, 2008, Volume: 172, Issue:6

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Collagen; Fibrosis; Interleukin-13; Mice; Receptor, Adenosine A2A; Skin; Transforming Growth Factor beta1; Triazines; Triazoles

2008
Morphology and function of dog arterial grafts preserved in UW-solution.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 1995, Volume: 10, Issue:4

    Topics: Adenosine; Allopurinol; Animals; Carotid Arteries; Cold Temperature; Dogs; Endothelium, Vascular; Female; Fibrosis; Glutathione; Insulin; Methacholine Chloride; Microscopy, Electron, Scanning; Muscarinic Agonists; Muscle, Smooth, Vascular; Organ Preservation Solutions; Phenylephrine; Raffinose; Sodium Chloride; Time Factors; Tissue Preservation; Tissue Survival; Transplantation, Autologous; Transplantation, Homologous; Vascular Patency; Vasoconstrictor Agents; Veins

1995
Frozen section evaluation of donor livers before transplantation.
    Transplantation, 1993, Volume: 56, Issue:6

    Topics: Adenosine; Adult; Allopurinol; Azo Compounds; Child; Fatty Liver; Female; Fibrosis; Frozen Sections; Glutathione; Hepatitis; Humans; Hypertonic Solutions; Insulin; Ischemia; Liver; Liver Transplantation; Male; Necrosis; Organ Preservation; Organ Preservation Solutions; Raffinose; Staining and Labeling; Survival Rate; Tissue Donors

1993
Adenosine inhibits collagen and protein synthesis in cardiac fibroblasts: role of A2B receptors.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:4

    Topics: 2-Chloroadenosine; Adenosine; Animals; Cardiovascular Agents; Cell Culture Techniques; Cell Division; Collagen; Fibroblasts; Fibrosis; Heart Ventricles; Male; Myocardial Infarction; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1

1998
Sequential dermal microvascular and perivascular changes in the development of scleroderma.
    The Journal of pathology, 1992, Volume: 166, Issue:3

    Topics: Adenosine; Adolescent; Adult; Aged; Autoradiography; Blood Vessels; Endothelium, Vascular; Female; Fibrin; Fibrosis; Humans; Immunohistochemistry; Male; Mast Cells; Microcirculation; Microscopy, Electron; Middle Aged; Scleroderma, Systemic; Skin

1992
Adenosine partially prevents cirrhosis induced by carbon tetrachloride in rats.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:2

    Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Tetrachloride; Collagen; Fibrosis; Liver; Liver Cirrhosis, Experimental; Male; Necrosis; Proline; Rats; Rats, Inbred Strains

1990
Subendomyocardial exhaustion of blood flow reserve and increased fibrosis in conscious dogs with heart failure.
    Circulation research, 1989, Volume: 65, Issue:4

    Topics: Adenosine; Animals; Blood Pressure; Cardiac Output, Low; Consciousness; Coronary Circulation; Dogs; Endocardium; Female; Fibrosis; Heart; Hemodynamics; Male; Myocardium

1989