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adenosine and B-Cell Chronic Lymphocytic Leukemia

adenosine has been researched along with B-Cell Chronic Lymphocytic Leukemia in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's2 (12.50)18.2507
2000's5 (31.25)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Blake, D; Chen, R; Chen, Y; Keating, MJ; Plunkett, W; Wierda, WG; Xiong, P; Zheleva, D1
Bernatova, S; Coma, M; Dedinska, K; Gabzdilova, J; Giertlova, M; Guman, T; Hajikova, M; Kicova, M; Michalova, Z; Sarissky, M; Veselinyova, D1
Chen, SS; Chiorazzi, N; Covey, T; Dadashian, EL; Herman, SEM; Izumi, R; Krantz, F; Lannutti, BJ; Mora-Jensen, HI; Niemann, CU; Ulrich, R; Wiestner, A1
Arruga, F; Deaglio, S; Vaisitti, T1
Cai, Y; Feng, L; Wang, X1
Błoński, JZ; Kiliańska, ZM; Leśnikowski, ZJ; Mieczkowski, A; Olejniczak, AB; Robak, T; Żołnierczyk, JD1
Drew, BG; Kingwell, BA1
Defoiche, J; Hegedus, A; Lagneaux, L; Macallan, DC; Pettengell, R; Willems, L; Zhang, Y1
Brusa, D; Coscia, M; D'Arena, G; Deaglio, S; Gaidano, G; Horenstein, AL; Inghirami, G; Laurenti, L; Malavasi, F; Robson, SC; Rossi, D; Serra, S; Tripodo, C; Vaisitti, T1
Feng, G; Gandhi, V; Krett, NL; McBrayer, SK; Qian, J; Rosen, ST; Shanmugam, M; Yarrington, M1
Barragán, M; Bellosillo, B; Campàs, C; Colomer, D; Gil, J; Lopez, JM; Santidrián, AF1
Balakrishnan, K; Gandhi, V; Keating, MJ; Wierda, WG1
Agostinho, AB; Carlucci, F; Galieni, P; Marinello, E; Porcelli, B; Rosi, F; Tabucchi, A; Zanoni, L1
Conigrave, AD; Fernando, KC; Gu, B; Luttrell, BM; Tasevski, V; Wiley, JS; Zhang, W1
Chen, R; Jamieson, GP; Wiley, JS; Wiley, MJ1
Blanc, CM; Cataldo, F; Derossi, G; Ho, AD; Kuse, R; Lauria, F; McVie, G; Stryckmans, P; Thaler, J; Willemze, R1

Reviews

3 review(s) available for adenosine and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Targeting the Adenosinergic Axis in Chronic Lymphocytic Leukemia: A Way to Disrupt the Tumor Niche?
    International journal of molecular sciences, 2018, Apr-12, Volume: 19, Issue:4

    Topics: Adenosine; Adenosine Triphosphate; Animals; Antineoplastic Agents; Gene Regulatory Networks; Humans; Hypoxia; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Targeted Therapy; Signal Transduction; Stem Cell Niche; Tumor Microenvironment

2018
Targeting the tumor promoting effects of adenosine in chronic lymphocytic leukemia.
    Critical reviews in oncology/hematology, 2018, Volume: 126

    Topics: Adenosine; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Targeted Therapy; Signal Transduction; Tumor Microenvironment

2018
Acadesine, an adenosine-regulating agent with the potential for widespread indications.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:12

    Topics: Adenosine; Aminoimidazole Carboxamide; Coronary Artery Bypass; Diabetes Mellitus; Humans; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Myocardial Reperfusion Injury; Ribonucleosides

2008

Trials

1 trial(s) available for adenosine and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Pentostatin (2'deoxycoformycin) for the treatment of lymphoid neoplasms.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Antineoplastic Agents; Coformycin; DNA, Neoplasm; Drug Evaluation; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Multicenter Studies as Topic; Neoplasm Proteins; Pentostatin; Ribonucleosides; Sezary Syndrome

1989

Other Studies

12 other study(ies) available for adenosine and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Cyclin-dependent kinase inhibitor fadraciclib (CYC065) depletes anti-apoptotic protein and synergizes with venetoclax in primary chronic lymphocytic leukemia cells.
    Leukemia, 2022, Volume: 36, Issue:6

    Topics: Adenosine; Apoptosis; Apoptosis Regulatory Proteins; Bridged Bicyclo Compounds, Heterocyclic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Myeloid Cell Leukemia Sequence 1 Protein; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Roscovitine; Sulfonamides; Tumor Microenvironment

2022
The expression of CD73 on pathological B-cells is associated with shorter overall survival of patients with CLL.
    Neoplasma, 2020, Volume: 67, Issue:4

    Topics: 5'-Nucleotidase; Adenosine; B-Lymphocytes; Biomarkers, Tumor; Flow Cytometry; GPI-Linked Proteins; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Prognosis

2020
Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Oct-01, Volume: 23, Issue:19

    Topics: Adenosine; Agammaglobulinaemia Tyrosine Kinase; Animals; Apoptosis; B-Lymphocytes; Benzamides; Cell Line, Tumor; Cell Proliferation; Class Ia Phosphatidylinositol 3-Kinase; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazines; Quinolines; Tumor Microenvironment

2017
In vitro antileukemic activity of novel adenosine derivatives bearing boron cluster modification.
    Bioorganic & medicinal chemistry, 2016, 11-01, Volume: 24, Issue:21

    Topics: Adenosine; Antineoplastic Agents; Apoptosis; Boron; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic, B-Cell; Structure-Activity Relationship

2016
Measurement of ribosomal RNA turnover in vivo by use of deuterium-labeled glucose.
    Clinical chemistry, 2009, Volume: 55, Issue:10

    Topics: Adenosine; AIDS-Related Complex; Cell Line, Tumor; Cell Proliferation; Deuterium; Gas Chromatography-Mass Spectrometry; Glucose; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymph Nodes; Lymphocytes; Lymphoma, Non-Hodgkin; Male; Middle Aged; Models, Biological; Ribonucleosides; RNA, Ribosomal; Sarcoma, Kaposi

2009
CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death.
    Blood, 2011, Dec-01, Volume: 118, Issue:23

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Antigens, CD; Antineoplastic Agents, Phytogenic; Apyrase; Autocrine Communication; Cell Death; Cell Differentiation; Cell Movement; Cell Survival; Etoposide; Extracellular Space; GPI-Linked Proteins; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Paracrine Communication; Receptor, Adenosine A2A; Tumor Cells, Cultured

2011
Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: 2-Chloroadenosine; Adenosine; Cell Line, Tumor; Clinical Trials, Phase I as Topic; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucosephosphate Dehydrogenase; Hematologic Neoplasms; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Multiple Myeloma; Neoplasm Proteins; Pentose Phosphate Pathway; RNA, Neoplasm

2012
Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes.
    Blood, 2003, May-01, Volume: 101, Issue:9

    Topics: Adenosine; Amino Acid Chloromethyl Ketones; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antimetabolites, Antineoplastic; Apoptosis; B-Lymphocytes; Caspases; Cyclic AMP-Dependent Protein Kinases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; MAP Kinase Signaling System; Mitochondria; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Neoplastic Stem Cells; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Ribonucleosides; Ribonucleotides; T-Lymphocytes; Tubercidin; Tumor Cells, Cultured

2003
Mechanisms of cell death of chronic lymphocytic leukemia lymphocytes by RNA-directed agent, 8-NH2-adenosine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Sep-15, Volume: 11, Issue:18

    Topics: Adenosine; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Apoptosis; Chromatography, High Pressure Liquid; Humans; Immunoblotting; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; X-Linked Inhibitor of Apoptosis Protein

2005
Behaviour of human lymphocytic isoenzymes of 5'-nucleotidase.
    Life sciences, 1998, Volume: 62, Issue:25

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Aged; B-Lymphocytes; Case-Control Studies; Cell Communication; Female; Humans; Hydrolysis; Isoenzymes; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Signal Transduction; T-Lymphocytes

1998
P2Y(11) receptor expression by human lymphocytes: evidence for two cAMP-linked purinoceptors.
    European journal of pharmacology, 2001, Aug-31, Volume: 426, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Messenger

2001
The ATP4- receptor-operated ion channel of human lymphocytes: inhibition of ion fluxes by amiloride analogs and by extracellular sodium ions.
    Archives of biochemistry and biophysics, 1992, Feb-01, Volume: 292, Issue:2

    Topics: Adenosine; Adenosine Triphosphate; Amiloride; Calcium; Cell Membrane Permeability; Cytosol; In Vitro Techniques; Ion Channels; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Ribonucleotides; Rubidium; Sodium

1992