adenosine has been researched along with Asthma in 184 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 45 (24.46) | 18.7374 |
1990's | 37 (20.11) | 18.2507 |
2000's | 70 (38.04) | 29.6817 |
2010's | 22 (11.96) | 24.3611 |
2020's | 10 (5.43) | 2.80 |
Authors | Studies |
---|---|
Fan, L; Shen, F; Sun, D; Wang, Z; Yang, H | 1 |
Dong, J; Huang, X; Qin, J; Tang, W; Tang, Z; Teng, F; Wang, S; Wei, Y; Wuniqiemu, T; Zhou, Y; Zhu, X | 1 |
Li, HM; Li, SM; Li, XM; Mo, BW; Xiao, B; Yang, J | 1 |
Godinho, RO; Jackson, EK; Pacini, ESA; Satori, NA | 1 |
Deng, K; Fang, XM; Huang, D; Li, WM; Liu, D; Liu, L; Liu, Y; Luo, FM; Oliver, BG; Wan, HJ; Wang, G; Wang, J; Wang, L; Zhang, HP; Zhang, L; Zhang, X | 1 |
Li, L; Xu, L; Yan, C; Zhou, L | 1 |
Chen, ZH; Du, J; Jia, LX; Liu, TT; Piao, CM; Shen, HH; Wang, YL; Zhang, J; Zhang, Z; Zheng, S | 1 |
Brogan, R; Ford, TJ; Morrow, A | 1 |
Almqvist, G; Eriksson, L; Leaker, BR; Lindgren, S; O'Connor, B; Singh, D; Young, B | 1 |
Chen, D; Li, H; Li, J; Lu, T; Luo, X; Ma, R; Sun, W; Wen, W; Xu, R | 1 |
Choi, H; Jang, S; Kim, H; Kim, SM; Kim, TD; Kim, VN; Lee, JW; Lee, YS | 1 |
Armoni Domany, K; Ater, D; Golan-Lagziel, T; Mandelberg, A; Wolfson, Y | 1 |
Boudewijn, IM; Cox, CA; Frijlink, HW; Hagedoorn, P; Lexmond, AJ; Schokker, S; Ten Hacken, NHT; van den Berge, M; Vonk, JM; Vroegop, SJ | 1 |
Carlsen, KH; Coates, AL; Cockcroft, DW; Culver, BH; de Jongh, FHC; Diamant, Z; Gauvreau, GM; Hall, GL; Hallstrand, TS; Horvath, I; Joos, G; Kaminsky, DA; Laube, BL; Leuppi, JD; Sterk, PJ; Wanger, J | 1 |
Boudewijn, IM; Cox, CA; Farenhorst, MP; Frijlink, HW; Hagedoorn, P; Kerstjens, HAM; Lexmond, AJ; Schokker, S; Ten Hacken, NHT; van den Berge, M; Vonk, JM; Vroegop, SJ | 1 |
Chen, H; Chen, X; Chen, Y; He, D; Shen, L; Wang, J; Xia, C; Yan, X; Zeng, M; Zhu, D | 1 |
Borah, P; Deb, PK; Deka, S; Mailavaram, RP | 1 |
Butler, K; Maya, J; Teng, R | 1 |
Cui, Y; Erb, KJ; Gantner, F; Mayer, H; Schuetz, JD; Schymeinsky, J; Tilp, C; Tomsic, C; Wollin, L | 1 |
Cicala, C; Ialenti, A | 1 |
Hall, M; Pencharz, D; Quigley, AM; Wagner, TL | 1 |
Bult, W; de Boer, AH; Frijlink, HW; Hagedoorn, P; Lexmond, AJ; ten Hacken, NH; van der Wiel, E | 1 |
Dekel, O; Rudich, N; Sagi-Eisenberg, R | 1 |
Alessandrini, F; Behrendt, H; Ernst, D; Ferreira, F; Frank, U; Gilles, S; Gutermuth, J; Hauser, M; Oeder, S; Ohnmacht, C; Ring, J; Schmidt-Weber, C; Schmitt-Kopplin, P; Traidl-Hoffmann, C; Wimmer, M; Winkler, JB | 1 |
Aryan, Z; Rezaei, N | 1 |
Linden, J; Pei, H | 1 |
Gao, QZ; Wei, J; Yu, WQ | 1 |
Benfatto, GT; Polosa, R | 1 |
Barnard, A; Mantell, SJ; Stuart, EF; Trevethick, MA; Wright, KN; Yeadon, M | 1 |
Polosa, R | 1 |
Wilson, CN | 1 |
Derom, E; Engelstätter, R; Joos, GF; Kaufman, JM; Louis, R; Tiesler, C | 1 |
Notghi, A; Smith, NB; Sundram, F | 1 |
Boucher, RC; Boysen, G; Collins, LB; Esther, CR; Ghio, AJ; Olsen, BM; Swenberg, JW | 1 |
Ansari, HR; Batchelor, TP; Dey, RD; Ledent, C; Mustafa, SJ; Nadeem, A; Ponnoth, DS | 1 |
Brown, R; Mustafa, SJ; Nadeem, A; Page, CP; Spina, D; Wilson, CN | 1 |
Caruso, M; Polosa, R; Tringali, G; Varani, K | 1 |
Barrett, RJ; Busse, WW; Katial, RK; Lockey, RF; McFadden, ER; Murray, JJ; Pixton, GC; Schwartz, LB; Weiler, JM | 1 |
Björnsson, E; Eriksson, BM; Hedenström, H; Högman, M; Janson, C; Lúdvíksdóttir, D; Venge, P | 1 |
Gyu Jeon, S; Kim, YK; Kim, YS; Moon, HG; Oh, SY; Song Gho, Y; Tae, YM; Zhu, Z | 1 |
Mustafa, SJ; Nadeem, A; Ponnoth, DS; Tilley, S | 1 |
Gomez, G; Schwartz, LB; Zhao, W | 1 |
Fernández-Nieto, M; Madero, MF; Manso, L; Ruiz-García, M; Sastre, J | 1 |
Calzetta, L; Cazzola, M; Facciolo, F; Matera, MG; Page, CP; Rendina, EA; Spina, D | 1 |
Barranco, P; Bobolea, I; Calderon, O; Guillén, D; Lopez-Carrasco, V; Quirce, S | 1 |
Barát, E; Csoma, Z; Herjavecz, I; Horváth, I; Huszár, E; Molnár Világos, G; Vass, G; Vizi, E | 1 |
Fan, M; Mustafa, SJ; Qin, W | 1 |
Polosa, R; Spicuzza, L | 1 |
Lin, Y; Wang, Z; Zhou, X; Zhu, Y | 1 |
Ali, S; Gouin, S | 1 |
Fozard, JR | 1 |
Grünig, G | 1 |
Bonfiglio, C; Polosa, R; Spicuzza, L | 1 |
Di Maria, GU; Polosa, R; Spicuzza, L | 1 |
Chen, P; He, S; Xie, H | 1 |
Avital, A; Bardach, E; Berkman, N; Breuer, R; Godfrey, S; Springer, C | 1 |
Ehrmann, D; Hooker, JL; Kukoly, C; Nyce, J; Salleng, K; Sandrasagra, A; Shibata, Y; Van Scott, MR; Westergaard, G | 1 |
Holgate, ST; Rorke, S | 1 |
de Meer, G; Marks, GB; Postma, DS | 1 |
BAVAY, J; GRENIER, J; LUTIER, F | 1 |
Ennis, M; Heaney, LG; Livingston, M | 1 |
Chen, P; He, SH; Xie, H | 1 |
Biaggioni, I; Feoktistov, I; Goldstein, AE; Matafonov, A; Ryzhov, S; Zeng, D | 1 |
Basbaum, C; Fahy, J; Gallup, M; Khong, A; Maltseva, I; McNamara, N; Sucher, A | 1 |
Cushley, MJ; Holgate, ST; Tattersfield, AE | 4 |
Boucher, RC; Tilley, SL | 1 |
Joos, G; Pauwels, R; Van Schoor, J | 1 |
Lauretta, D; Polosa, R | 1 |
Holgate, ST | 4 |
Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN | 1 |
Joos, GF | 1 |
Fan, M; Jamal Mustafa, S | 1 |
Blackburn, MR; Mohsenin, A | 1 |
Arcidiacono, G; Polosa, R; Russo, C | 1 |
Di Maria, G; Polosa, R; Spicuzza, L | 1 |
Caruso, M; Holgate, ST; Polosa, R | 1 |
Liesker, JJ; Postma, DS; Rutgers, SR; Ten Hacken, NH; Timens, W; Zeinstra-Smith, M | 1 |
Alvarez, C; Ferreira, A; Gatica, H; Goecke, IA; Henríquez, J; Molina, ML; Salas, K | 1 |
Alam, M; Burki, NK; Lee, LY | 1 |
Belardinelli, L; Fan, M; Mustafa, SJ; Nadeem, A; Zeng, D; Zhong, H | 1 |
Matera, MG; Polosa, R | 1 |
Hylkema, MN; Postma, DS; van den Berge, M; Versluis, M | 1 |
Hammer, J; Newth, CJ; Trachsel, D | 1 |
Allman, KC; Chan, M; Couthino, B; van Gaal, WJ | 1 |
Adinolfi, B; Blandizzi, C; Breschi, MC; Calderone, V; Camici, M; Fogli, S; Martinelli, C; Martinotti, E; Nieri, P | 1 |
Dip, RG | 1 |
Brown, RA; Clarke, GW; Coote, JE; Denyer, JC; Hurle, MJ; Ledbetter, CL; Murdoch, RD; O'Connor, BJ; Page, CP; Savage, TJ; Simcock, DE; Spina, D | 1 |
Anderson, SD | 1 |
Bochenek, G; Gielicz, A; Nizankowska, E; Szczeklik, A | 1 |
Mustafa, SJ; Nadeem, A; Ponnoth, DS | 1 |
Brown, RA; Page, CP; Spina, D | 1 |
Patton, JW; Sharma, GK | 1 |
Chason, KD; Deshpande, DA; Fredholm, BB; Hua, X; Penn, RB; Tilley, SL | 1 |
Pauwels, R | 1 |
Jenne, JW | 1 |
Persson, CG | 3 |
Cushley, MJ; Holgate, ST; Mann, JS | 2 |
Erjefält, I; Karlsson, JA; Persson, CG | 1 |
Martin, JG | 1 |
Biaggioni, I; Feoktistov, I | 2 |
DeGroff, CG; Silka, MJ | 1 |
Ali, S; Metzger, WJ; Mustafa, SJ | 2 |
Drake, I; Richards, R; Routledge, PA | 1 |
Joos, GF; Kips, JC; Pauwels, RA | 1 |
Broadley, KJ; Thorne, JR | 1 |
Ali, S; Driver, AG; Kukoly, CA; Mustafa, SJ | 1 |
Broadley, KJ; Lewis, CA | 1 |
Richardson, PJ | 1 |
Metzger, WJ; Nyce, JW | 1 |
Gavrilova, EV; Makarkov, AI; Poriadin, GV; Salmasi, ZhM | 1 |
Carpentier, PJ; Drajesk, JF; Joos, GF; Kips, JC; Pauwels, RA; Van Schoor, J | 1 |
Crimi, N; Mistretta, A; Polosa, R | 1 |
Holgate, ST; Polosa, R | 1 |
Dent, G; Rabe, KF | 1 |
Church, MK; Coward, WR; Sagara, H | 1 |
Abebe, W; Mustafa, SJ | 1 |
Ennis, M; Forsythe, P | 1 |
Fozard, JR; Hannon, JP | 1 |
Joos, GF; Pauwels, RA; Van Schoor, J | 1 |
Lumsden, G; Terry, P | 1 |
Banerjee, SK; Blackburn, MR; Chunn, JL; Colasurdo, GN; Young, HW | 1 |
Leonard, SA; Li, Y; Mannion, JC; Nyce, JW; Sandrasagra, A; Tang, L; Teng, K | 1 |
Banerjee, SK; Blackburn, MR; Volmer, JB; Young, HW | 1 |
He, Q; Yao, W; Zhang, X | 1 |
Ellis, KM; Fozard, JR; Mazzoni, L; Tigani, B; Villela Dantas, MF | 1 |
Holgate, ST; Polosa, R; Rorke, S | 1 |
Björck, T; Dahlén, SE; Gustafsson, LE | 1 |
Crimi, N; Mistretta, A; Oliveri, R; Palermo, F; Polosa, R; Settinieri, I | 1 |
Abazova, FI; Alieva, NG; Dukhanin, AS; Ogurtsov, SI; Omel'ianovskiĭ, VV; Sergeev, PV | 1 |
Joos, G; Kips, J; Pauwels, R | 1 |
Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
Church, MK; Holgate, ST; Polosa, R | 2 |
Driver, AG; Kukoly, CA; Metzger, WJ; Mustafa, SJ | 1 |
Diamond, L; Küng, M | 1 |
Akisawa, T; Nakagami, K; Narushima, M; Noguchi, E; Suzuki, H; Tanaka, K | 1 |
Finnerty, JP; Holgate, ST; Polosa, R | 1 |
Schwartz, LB | 1 |
Church, MK; Ng, WH; Polosa, R | 1 |
Crimi, N; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C | 1 |
Carapella, N; Filippelli, A; Loffreda, A; Marmo, E; Matera, MG; Montanaro, C; Santagata, A; Servodio, R; Susanna, V | 1 |
Steinberg, TH | 1 |
Church, MK; Holgate, ST | 1 |
Crimi, N; Distefano, SM; Mistretta, A; Oliveri, R; Palermo, F; Polosa, R; Vancheri, C | 1 |
Easton, J; Goldberg, B; Lad, P; Meltzer, S | 1 |
Borish, L; Joseph, B; Rocklin, RE; Sustiel, AM | 1 |
Karlsson, JA | 1 |
Crimi, N; Maccarrone, C; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C | 2 |
Erjefält, I; Gustafsson, B; Persson, CG | 1 |
Cushley, MJ; Holgate, ST | 1 |
Fredholm, BB | 1 |
Andersson, KE; Kjellin, G; Persson, CG | 1 |
Pauwels, R; van der Straeten, M | 1 |
Brancatisano, M; Brusasco, V; Crimi, E; Crimi, P; Losurdo, E | 2 |
Cacopardo, B; Crimi, N; Mistretta, A; Oliveri, R; Palermo, F; Vancheri, C | 1 |
Church, MK; Cushley, MJ; Featherstone, RL; Holgate, ST; Mann, JS | 1 |
Barnes, PJ | 2 |
Joos, G; Pauwels, R; Van der Straeten, M | 1 |
Bittera, I; Gyurkovits, K; Papp, A; Rápó, J | 1 |
Ma, JY | 1 |
Larsson, K; Sollevi, A | 1 |
Church, MK; Cushley, MJ; Holgate, ST; Mann, JS | 1 |
Chaperon, EA; Hiratani, M; McCall, MK; Townley, RG | 1 |
Church, MK; Cushley, MJ; Holgate, ST; Hughes, P; Mann, JS | 1 |
Bradding, P; Hardy, CC; Holgate, ST; Robinson, C | 1 |
Cushley, MJ; Holgate, ST; Mann, JS; Renwick, AG | 1 |
Wasserman, SI | 1 |
Holgate, ST; Mann, JS | 1 |
Cushley, MJ; Holgate, ST; Tallant, N | 1 |
58 review(s) available for adenosine and Asthma
Article | Year |
---|---|
Extracellular cAMP-Adenosine Pathway Signaling: A Potential Therapeutic Target in Chronic Inflammatory Airway Diseases.
Topics: Adenosine; Adenosine Monophosphate; Asthma; Humans; Receptors, Adrenergic; Signal Transduction | 2022 |
Emerging role of N6-methyladenosine RNA methylation in lung diseases.
Topics: Adenosine; Asthma; Humans; Lung Diseases; Lung Neoplasms; Methylation; RNA; RNA, Messenger | 2022 |
P1 Receptor Agonists/Antagonists in Clinical Trials - Potential Drug Candidates of the Future.
Topics: Adenosine; Asthma; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Ligands; Neoplasms; Parkinson Disease; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Pyrazoles; Receptors, Purinergic P1 | 2019 |
Toll-like receptors as targets for allergen immunotherapy.
Topics: Adenosine; Animals; Anti-Allergic Agents; Asthma; Clinical Trials as Topic; Desensitization, Immunologic; Humans; Lipid A; Molecular Targeted Therapy; Oligodeoxyribonucleotides; Oligonucleotides; Phenylacetates; Rhinitis, Allergic; Toll-Like Receptors; Vaccines | 2015 |
Treating lung inflammation with agonists of the adenosine A2A receptor: promises, problems and potential solutions.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Inflammation; Lung; Pulmonary Disease, Chronic Obstructive | 2008 |
Adenosine receptors and asthma in humans.
Topics: Adenosine; Animals; Anti-Asthmatic Agents; Asthma; Clinical Trials as Topic; Drug Delivery Systems; Drug Design; Humans; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction | 2008 |
Adenosine receptors and asthma.
Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Humans; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1 | 2009 |
Adenosine and adenosine receptors: their contribution to airway inflammation and therapeutic potential in asthma.
Topics: Adenosine; Anti-Asthmatic Agents; Asthma; Drug Delivery Systems; Humans; Inflammation; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1 | 2009 |
The role of adenosine as a novel bronchoprovocant in asthma.
Topics: Adenosine; Administration, Inhalation; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Humans | 2003 |
[The effects of adenosine, interleukin-1 and theophylline on the expression of A2 adenosine receptor mRNAs in peripheral blood mononuclear cells from asthmatic patients].
Topics: Adenosine; Adolescent; Adult; Asthma; Female; Humans; Interleukin-1; Leukocytes, Mononuclear; Male; Middle Aged; Receptors, Purinergic P1; RNA, Messenger; Theophylline | 2001 |
The case for a role for adenosine in asthma: almost convincing?
Topics: Adenosine; Adenosine Deaminase; Animals; Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Bronchodilator Agents; Humans; Receptors, Adenosine A2; Theophylline | 2003 |
Research applications and implications of adenosine in diseased airways.
Topics: Adenosine; Administration, Inhalation; Animals; Asthma; Bronchoconstriction; Diagnosis, Differential; Humans; Inflammation; Pulmonary Disease, Chronic Obstructive; Vasodilator Agents | 2003 |
Targeting adenosine receptors: novel therapeutic targets in asthma and chronic obstructive pulmonary disease.
Topics: Adenosine; Asthma; Bronchoconstriction; Humans; Inflammation; Mast Cells; Pulmonary Disease, Chronic Obstructive; Receptors, Purinergic P1 | 2002 |
Direct or indirect stimuli for bronchial challenge testing: what is the relevance for asthma epidemiology?
Topics: Adenosine; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Histamine; Humans; Methacholine Chloride; Predictive Value of Tests; Prevalence | 2004 |
Adenosine, inflammation and asthma--a review.
Topics: Adenosine; Animals; Asthma; Basophils; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Humans; Inflammation; Mast Cells; Receptors, Purinergic P1 | 2004 |
Indirect bronchial hyper-responsiveness: the coming of age of a specific group of bronchial challenges.
Topics: Adenosine; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Exercise Test; Humans; Mannitol; Osmosis; Sports | 2005 |
[Indirect bronchial provocation tests: a new, specific group of bronchial provocation tests for asthma].
Topics: Adenosine; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Humans; Pulmonary Ventilation; Tachykinins | 2005 |
Adenosine signaling in asthma and chronic obstructive pulmonary disease.
Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Humans; Lung; Mast Cells; Mice; Pulmonary Disease, Chronic Obstructive; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1 | 2006 |
Adenosine receptors: promising targets for the development of novel therapeutics and diagnostics for asthma.
Topics: Adenosine; Animals; Anti-Asthmatic Agents; Asthma; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Receptors, Purinergic P1 | 2006 |
Adenosine in the airways: implications and applications.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Diagnosis, Differential; Humans; Pulmonary Disease, Chronic Obstructive; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Respiratory System | 2006 |
Adenosine signalling in airways.
Topics: Adenosine; Adenosine Monophosphate; Animals; Asthma; Bronchial Provocation Tests; Diagnosis, Differential; Humans; Pulmonary Disease, Chronic Obstructive; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Adenosine A2; Respiratory System; Signal Transduction | 2006 |
Role of adenosine receptors in the treatment of asthma and chronic obstructive pulmonary disease: recent developments.
Topics: Adenosine; Asthma; Bronchoconstriction; Humans; Models, Biological; Pulmonary Disease, Chronic Obstructive; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Technology, Pharmaceutical | 2007 |
Adenosine receptor modulation: potential implications in veterinary medicine.
Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Cat Diseases; Cats; Horse Diseases; Horses; Inflammation; Pulmonary Disease, Chronic Obstructive; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction | 2009 |
Provocative challenges to help diagnose and monitor asthma: exercise, methacholine, adenosine, and mannitol.
Topics: Adenosine; Adolescent; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Child, Preschool; Exercise; Humans; Mannitol; Methacholine Chloride; Respiratory Function Tests | 2008 |
Adenosine receptors and asthma.
Topics: Adenosine; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Humans; Inflammation; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1 | 2008 |
[Animal experiments and clinical studies on the role of adenosine in bronchial asthma].
Topics: Adenosine; Adult; Animals; Asthma; Atropine; Basophils; Bronchi; Bronchodilator Agents; Cromolyn Sodium; Double-Blind Method; Female; Hexamethonium Compounds; Humans; Inosine; Lung; Male; Mast Cells; Random Allocation; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Urethane; Vagotomy; Xanthines | 1984 |
Theophylline use in asthma. Some current issues.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Asthma; Bronchi; Cardiac Output; Cyclic AMP; Drug Therapy, Combination; Humans; Kinetics; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Purinergic; Stroke Volume; Theophylline | 1984 |
The profile of action of enprofylline, or why adenosine antagonism seems less desirable with xanthine antiasthmatics.
Topics: Adenosine; Animals; Asthma; Bronchi; Cats; Central Nervous System; Chemical Phenomena; Chemistry; Diuresis; Guinea Pigs; Heart; Humans; Lung; Mice; Nausea; Rats; Structure-Activity Relationship; Theophylline; Xanthines | 1983 |
[Animal models of bronchial hyperreactivity].
Topics: Adenosine; Animals; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chronic Disease; Cytokines; Dextrans; Disease Models, Animal; Dogs; Guinea Pigs; Inflammation; Leukotrienes; Lipoxygenase; Mast Cells; Ozone; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Tachykinins | 1994 |
Direct and indirect bronchial responsiveness.
Topics: Adenosine; Asthma; Bronchi; Bronchial Provocation Tests; Humans; Tachykinins | 1993 |
Purine derivatives in the study of allergic inflammation in respiratory diseases.
Topics: Adenosine; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Guinea Pigs; Humans; Inflammation; Purine Nucleosides; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal | 1997 |
Adenosine bronchoprovocation: a promising marker of allergic inflammation in asthma?
Topics: Adenosine; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Humans | 1997 |
Theophylline and airway inflammation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Administration, Oral; Anti-Inflammatory Agents; Asthma; Biopsy; Bronchi; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Eosinophils; Humans; Leukocyte Count; Lymphocyte Count; Theophylline | 1998 |
Asthma, adenosine, mast cells and theophylline.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Asthma; Cytokines; Humans; Immunohistochemistry; Lung; Mast Cells; NF-kappa B; Theophylline | 1998 |
Adenosine, mast cells and asthma.
Topics: Adenosine; Animals; Asthma; Bronchi; Bronchoalveolar Lavage; Humans; In Vitro Techniques; Mast Cells; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists | 1999 |
Experimental models in asthma.
Topics: Adenosine; Asthma; Asthma, Exercise-Induced; Bronchoconstriction; Cold Temperature; Histamine; Humans; Mast Cells | 1999 |
Species differences in adenosine receptor-mediated bronchoconstrictor responses.
Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Guinea Pigs; Humans; Rabbits; Rats; Receptors, Purinergic P1; Species Specificity | 2000 |
Indirect bronchial hyperresponsiveness in asthma: mechanisms, pharmacology and implications for clinical research.
Topics: Adenosine; Adenosine Monophosphate; Adrenergic beta-Antagonists; Aerosols; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Exercise; Humans; Propranolol; Pulmonary Ventilation; Sulfites; Sulfur Dioxide; Tachykinins | 2000 |
RASONs: a novel antisense oligonucleotide therapeutic approach for asthma.
Topics: Adenosine; Asthma; Gene Expression Regulation; Humans; Oligonucleotides, Antisense; Receptors, Purinergic P1 | 2001 |
Adenosine: a key effector molecule of asthma or just another mediator?
Topics: Adenosine; Asthma; Humans; Lung | 2002 |
Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease.
Topics: Adenosine; Adenosine Monophosphate; Asthma; Bronchi; Bronchoconstriction; Humans; Pulmonary Disease, Chronic Obstructive | 2002 |
Processes and bronchial hyperresponsiveness.
Topics: Adenosine; Animals; Asthma; Bronchi; Humans; Inflammation; Neurokinin A; Neuropeptides; Rats | 1991 |
Adenosine: a positive modulator of airway inflammation in asthma.
Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Humans; Inflammation; Mast Cells; Respiratory Physiological Phenomena; Respiratory System | 1991 |
Tryptase, a mediator of human mast cells.
Topics: Adenosine; Anaphylaxis; Asthma; Basophils; Blood Coagulation; Humans; Immunoassay; Mast Cells; Mastocytosis; Muscle Contraction; Muscle, Smooth; Peptide Hydrolases | 1990 |
Adenosine bronchoconstriction in asthma: investigations into its possible mechanism of action.
Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Humans | 1990 |
Adenosine and adenosine receptors.
Topics: Adenosine; Animals; Asthma; Humans; Lung; Receptors, Purinergic | 1990 |
Adenosine in asthmatic lung.
Topics: Adenosine; Asthma; Bronchial Spasm; Histamine Release; Humans | 1988 |
Adenosine as a pro-inflammatory mediator in asthma.
Topics: Adenosine; Animals; Asthma; Humans; Inflammation | 1989 |
Purines and sensory neuropeptides in human asthma.
Topics: Adenosine; Asthma; Humans; Neuropeptides; Receptors, Neurotransmitter; Receptors, Purinergic; Receptors, Tachykinin; Tachykinins | 1987 |
Xanthines--symptomatic or prophylactic in asthma?
Topics: Adenosine; Animals; Asthma; Bronchi; Humans; In Vitro Techniques; Inflammation; Muscle Contraction; T-Lymphocytes; Xanthines | 1988 |
Effects of enprofylline and theophylline may show the role of adenosine.
Topics: Adenosine; Animals; Asthma; Brain; Bronchodilator Agents; Caffeine; Diuresis; Fatty Acids, Nonesterified; Gastric Acid; Heart; Humans; Kidney; Kinetics; Lung; Natriuresis; Phosphodiesterase Inhibitors; Receptors, Cell Surface; Receptors, Purinergic; Respiration; Seizures; SRS-A; Theophylline; Vasoconstriction; Vasodilation; Xanthines | 1986 |
Relationships between adenosine, cyclic nucleotides, and xanthines in asthma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Asthma; Bronchi; Catecholamines; Humans; Xanthines | 1986 |
Inflammatory mechanisms and nocturnal asthma.
Topics: Adenosine; Asthma; Blood Platelets; Circadian Rhythm; Eosinophils; Epithelium; Histamine; Humans; Inflammation; Lymphocytes; Macrophages; Mast Cells; Neutrophils; Platelet Activating Factor; Prostaglandins; SRS-A | 1988 |
Bronchial hyperresponsiveness is not bronchial hyperresponsiveness is not bronchial asthma.
Topics: Acetylcholine; Adenosine; Airway Resistance; Animals; Asthma; Bronchi; Histamine; Humans; Methacholine Chloride; Methacholine Compounds; Neuropeptides | 1988 |
Mechanisms and significance of adenosine-induced bronchoconstriction in asthma.
Topics: Adenosine; Adenosine Monophosphate; Airway Obstruction; Aminophylline; Asthma; Bronchi; Bronchodilator Agents; Xanthines | 1987 |
The action of purines on human airways.
Topics: Adenine Nucleotides; Adenosine; Asthma; Bronchi; Humans; Purine Nucleosides; Purine Nucleotides; Purines; Respiratory System | 1986 |
Development of safer xanthine drugs for treatment of obstructive airways disease.
Topics: Adenosine; Animals; Asthma; Brain; Cardiovascular System; Humans; Lung; Lung Diseases, Obstructive; Structure-Activity Relationship; Xanthines | 1986 |
Mast cell mediators in the blood of patients with asthma.
Topics: Adenosine; Antigens; Asthma; Bronchial Spasm; Chemotactic Factors; Histamine; Humans; Mast Cells; Platelet Activating Factor; Urticaria | 1985 |
22 trial(s) available for adenosine and Asthma
Article | Year |
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Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-induced responses in patients with mild asthma: a double-blind, randomised, parallel-group study.
Topics: Adenosine; Administration, Intranasal; Adolescent; Adult; Allergens; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Double-Blind Method; Female; Humans; Male; Middle Aged; Phenylacetates; Toll-Like Receptor 7; Treatment Outcome; Young Adult | 2019 |
Bronchial Provocation Testing Can Be Improved by Using Dry Powder Adenosine Instead of Nebulized Adenosine Monophosphate.
Topics: Adenosine; Adenosine Monophosphate; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dry Powder Inhalers; Female; Forced Expiratory Volume; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis | 2018 |
Effect of ticagrelor on pulmonary function in healthy elderly volunteers and asthma or chronic obstructive pulmonary disease patients.
Topics: Adenosine; Aged; Asthma; Double-Blind Method; Female; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Purinergic P2Y Receptor Antagonists; Respiratory Rate; Respiratory Transport; Ticagrelor | 2013 |
Effects of ciclesonide and fluticasone on cortisol secretion in patients with persistent asthma.
Topics: Adenosine; Adolescent; Adult; Aged; Albuterol; Analysis of Variance; Androstadienes; Anti-Allergic Agents; Area Under Curve; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Female; Fluticasone; Forced Expiratory Volume; Humans; Hydrocortisone; Least-Squares Analysis; Male; Methacholine Chloride; Middle Aged; Placebos; Pregnenediones; Salmeterol Xinafoate; Spirometry; Treatment Outcome | 2009 |
Pharmacological stress myocardial perfusion scintigraphy: use of a modified adenosine protocol in patients with asthma.
Topics: Adenosine; Aged; Albuterol; Asthma; Bronchial Spasm; Case-Control Studies; Female; Humans; Male; Myocardial Perfusion Imaging; Premedication; Safety; Stress, Physiological; Time Factors | 2009 |
Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis.
Topics: Adenosine; Adenosine Monophosphate; Adolescent; Asthma; Biomarkers; Breath Tests; Child; Child, Preschool; Cross-Sectional Studies; Cystic Fibrosis; Humans; Mass Spectrometry; Predictive Value of Tests; Respiratory Function Tests; Signal Transduction; Urea; Young Adult | 2009 |
Safety of binodenoson, a selective adenosine A2A receptor agonist vasodilator pharmacological stress agent, in healthy subjects with mild intermittent asthma.
Topics: Adenosine; Adolescent; Adult; Analysis of Variance; Asthma; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Female; Humans; Male; Middle Aged; Placebos; Respiratory Function Tests; Single-Blind Method; Treatment Outcome; Vasodilator Agents | 2009 |
Is methacholine challenge sufficient to rule out bronchial hyperresponsiveness in patients with suspected asthma?
Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Diagnosis, Differential; Female; Humans; Male; Methacholine Chloride; Middle Aged; Predictive Value of Tests; Prognosis; Sensitivity and Specificity | 2012 |
The effect of montelukast on bronchial provocation tests and exhaled nitric oxide levels in asthmatic patients.
Topics: Acetates; Adenosine; Administration, Oral; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Cyclopropanes; Exercise; Female; Humans; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Quinolines; Spirometry; Sulfides; Treatment Outcome; Vasodilator Agents | 2003 |
The pulmonary effects of intravenous adenosine in asthmatic subjects.
Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Dose-Response Relationship, Drug; Dyspnea; Female; Humans; Injections, Intravenous; Lung; Male; Respiratory Mechanics | 2006 |
The effect of ABT-761, a novel 5-lipoxygenase inhibitor, on exercise- and adenosine-induced bronchoconstriction in asthmatic subjects.
Topics: Adenosine; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Exercise; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Male; Middle Aged; Vasodilator Agents | 1997 |
Protective effects of inhaled ipratropium bromide on bronchoconstriction induced by adenosine and methacholine in asthma.
Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchoconstriction; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Ipratropium; Male; Methacholine Chloride; Middle Aged; Reflex; Vagus Nerve | 1992 |
Adenosine-induced bronchoconstriction in human asthmatics: effects of pretreatment with indomethacin or atropine sulfate.
Topics: Adenosine; Administration, Inhalation; Administration, Oral; Adult; Asthma; Atropine; Bronchial Provocation Tests; Bronchoconstrictor Agents; Double-Blind Method; Humans; Indomethacin; Male; Methacholine Chloride | 1990 |
Repeated exposure of asthmatic airways to inhaled adenosine 5'-monophosphate attenuates bronchoconstriction provoked by exercise.
Topics: Adenosine; Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchoconstriction; Female; Forced Expiratory Volume; Histamine; Humans; Male | 1990 |
Tachyphylaxis to repeated challenges with inhaled adenosine in asthmatic subjects.
Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Tachyphylaxis | 1990 |
Effect of sodium cromoglycate and nifedipine on adenosine-induced bronchoconstriction.
Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Calcium; Cromolyn Sodium; Double-Blind Method; Female; Humans; Ion Channels; Male; Nifedipine; Random Allocation | 1988 |
Comparative study of the effects of nedocromil sodium (4 mg) and sodium cromoglycate (10 mg) on adenosine-induced bronchoconstriction in asthmatic subjects.
Topics: Adenosine; Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Nedocromil; Quinolines; Random Allocation | 1988 |
Adenosine-induced bronchoconstriction: comparison between nedocromil sodium and sodium cromoglycate.
Topics: Adenosine; Adolescent; Adult; Asthma; Cromolyn Sodium; Female; Forced Expiratory Volume; Humans; Male; Nedocromil; Quinolines; Skin Tests | 1986 |
Influence of infused adenosine on bronchial tone and bronchial reactivity in asthma.
Topics: Adenosine; Adult; Asthma; Blood Pressure; Bronchi; Bronchial Provocation Tests; Female; Heart Rate; Humans; Infusions, Intravenous; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle, Smooth; Respiratory Function Tests | 1988 |
Enhancing effect of dipyridamole inhalation on adenosine-induced bronchospasm in asthmatic patients.
Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchi; Bronchial Spasm; Dipyridamole; Drug Synergism; Female; Humans; Male; Middle Aged | 1988 |
The combined effects of two pairs of mediators, adenosine with methacholine and prostaglandin D2 with histamine, on airway calibre in asthma.
Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchi; Dose-Response Relationship, Drug; Drug Synergism; Female; Histamine; Humans; Male; Methacholine Chloride; Methacholine Compounds; Prostaglandins D; Time Factors | 1986 |
Specific antagonism of adenosine-induced bronchoconstriction in asthma by oral theophylline.
Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchi; Bronchodilator Agents; Female; Forced Expiratory Volume; Histamine; Humans; Male; Random Allocation; Theophylline | 1985 |
104 other study(ies) available for adenosine and Asthma
Article | Year |
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m6A regulator-mediated RNA methylation modification patterns and immune microenvironment infiltration characterization in severe asthma.
Topics: Adenosine; Animals; Asthma; Biomarkers; Cellular Microenvironment; Computational Biology; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Methylation; Mice; Models, Biological; RNA, Messenger; ROC Curve; Severity of Illness Index; Transcriptome | 2021 |
Topics: Adenosine; Allergens; Animals; Asthma; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Epigenome; Female; Gene Expression Profiling; Humans; Hypersensitivity; Immunity; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Signal Transduction | 2021 |
m6A echoes with DNA methylation: Coordinated DNA methylation and gene expression data analysis identified critical m6A genes associated with asthma.
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Asthma; CCAAT-Enhancer-Binding Proteins; Data Analysis; DNA Methylation; Gene Expression; Humans; Mixed Function Oxygenases; Proto-Oncogene Proteins; RNA-Binding Proteins; Ubiquitin-Protein Ligases | 2022 |
Endogenous Adenosine 5'-Monophosphate, But Not Acetylcholine or Histamine, is Associated with Asthma Control, Quality of Life, and Exacerbations.
Topics: Acetylcholine; Adenosine; Adenosine Monophosphate; Asthma; Biomarkers; Chemokine CCL22; Histamine; Humans; Interleukin-13; Interleukin-17; Interleukin-4; Interleukin-5; Interleukin-6; Interleukin-8; Quality Control; Quality of Life; Sputum; Tumor Necrosis Factor-alpha | 2022 |
Abnormal adenosine metabolism of neutrophils inhibits airway inflammation and remodeling in asthma model induced by Aspergillus fumigatus.
Topics: Adenosine; Airway Remodeling; Animals; Aspergillus fumigatus; Asthma; Bronchoalveolar Lavage Fluid; Chemokines; Cytokines; Inflammation; Mice; Neutrophils; Plant Extracts | 2023 |
Incidence of acute bronchospasm during systemic adenosine administration for coronary angiography.
Topics: Adenosine; Aged; Asthma; Bronchial Spasm; Coronary Angiography; Humans; Incidence; Infusions, Intravenous; Middle Aged; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Vasodilator Agents | 2019 |
DZNep attenuates allergic airway inflammation in an ovalbumin-induced murine model.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Hypersensitivity; Inflammation; Lung; Mice; Mice, Inbred BALB C; Ovalbumin | 2021 |
RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis.
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Asthma; Cilia; Ciliopathies; Demethylation; Embryo, Mammalian; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Mice, Inbred C57BL; Mice, Knockout; Organogenesis; Phenotype; Respiratory Mucosa; RNA Stability; RNA, Messenger; Xenopus laevis | 2021 |
Can bronchial challenge test with adenosine or methacholine at preschool age predict school-age asthma?
Topics: Adenosine; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool; Female; Humans; Infant; Male; Methacholine Chloride; Schools | 2021 |
ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing.
Topics: Adenosine; Advisory Committees; Asthma; Bronchial Provocation Tests; Europe; Humans; Mannitol; Methacholine Chloride; Respiratory Hypersensitivity; Societies, Medical | 2018 |
Associations of AMP and adenosine induced dyspnea sensation to large and small airways dysfunction in asthma.
Topics: Adenosine; Adenosine Monophosphate; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dyspnea; Female; Forced Expiratory Volume; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Spirometry | 2019 |
Asthmatic Augmentation of Airway Vagal Activity Involves Decreased Central Expression and Activity of CD73 in Rats.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Asthma; Excitatory Postsynaptic Potentials; Male; Neurons; Rats; Rats, Sprague-Dawley; Vagus Nerve | 2019 |
The absence of mrp4 has no effect on the recruitment of neutrophils and eosinophils into the lung after LPS, cigarette smoke or allergen challenge.
Topics: Adenosine; Allergens; Animals; Asthma; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bronchoalveolar Lavage Fluid; Cyclic AMP; Cytokines; Diketopiperazines; Eosinophils; Heterocyclic Compounds, 4 or More Rings; Lipopolysaccharides; Lung; Mice; Multidrug Resistance-Associated Proteins; Neutrophils; Ovalbumin; Phosphodiesterase 4 Inhibitors; Propionates; Pulmonary Disease, Chronic Obstructive; Quinolines; Rolipram; Smoking; Th2 Cells; Time Factors | 2013 |
Adenosine signaling in airways: toward a promising antiasthmatic approach.
Topics: Adenosine; Animals; Anti-Asthmatic Agents; Asthma; Humans; Respiratory System; Signal Transduction | 2013 |
Rapid and severe adverse reaction to adenosine during a pharmacological stress test for a myocardial perfusion scan.
Topics: Adenosine; Albuterol; Asthma; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Myocardial Perfusion Imaging | 2013 |
Adenosine dry powder inhalation for bronchial challenge testing, part 2: proof of concept in asthmatic subjects.
Topics: Adenosine; Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dry Powder Inhalers; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Pilot Projects; Powders | 2014 |
Down-regulation of the A3 adenosine receptor in human mast cells upregulates mediators of angiogenesis and remodeling.
Topics: Adenosine; Adenosine A3 Receptor Antagonists; Amphiregulin; Anti-Inflammatory Agents; Asthma; Cell Line, Tumor; Dexamethasone; Down-Regulation; EGF Family of Proteins; Humans; Interleukin-6; Interleukin-8; Jurkat Cells; Lung; Mast Cells; Neovascularization, Pathologic; Osteopontin; Phosphorylation; Receptor, Adenosine A3; RNA Interference; RNA, Small Interfering; Up-Regulation; Vascular Endothelial Growth Factor A | 2015 |
Pollen-derived adenosine is a necessary cofactor for ragweed allergy.
Topics: Adenosine; Administration, Intranasal; Animals; Antigens, Plant; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Epithelial Cells; Female; Humans; Immunization; Lung; Mice; Mice, Inbred BALB C; Plant Extracts; Random Allocation; Respiratory Hypersensitivity; Risk Assessment; Sensitivity and Specificity; Th2 Cells | 2015 |
Adenosine influences myeloid cells to inhibit aeroallergen sensitization.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Asthma; Cell Polarity; Cells, Cultured; Drug Evaluation, Preclinical; Immunologic Factors; Lipopolysaccharides; Male; Mice, Inbred C57BL; Myeloid Cells; Receptor, Adenosine A2A; T-Lymphocytes | 2016 |
[Advances in the study of A2B adenosine receptor antagonists].
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Asthmatic Agents; Asthma; Humans; Pulmonary Artery; Structure-Activity Relationship; Xanthines | 2008 |
A2A adenosine receptor agonists for the treatment of asthma?
Topics: Adenosine; Adenosine A2 Receptor Agonists; Asthma; Humans; Receptor, Adenosine A2A; Treatment Outcome | 2008 |
Finding better therapeutic targets for patients with asthma: adenosine receptors?
Topics: Adenosine; Anti-Asthmatic Agents; Asthma; Drug Delivery Systems; Drug Design; Humans; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists | 2008 |
A2A adenosine receptor deficiency leads to impaired tracheal relaxation via NADPH oxidase pathway in allergic mice.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Asthma; Disease Models, Animal; Female; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; NADPH Oxidases; Phenethylamines; Reactive Oxygen Species; Receptor, Adenosine A2A; Signal Transduction; Trachea | 2009 |
Airway hyperresponsiveness, peak flow variability and inflammatory markers in non-asthmatic subjects with respiratory infections.
Topics: Adenosine; Adult; Aged; Air; Asthma; Biomarkers; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cold Temperature; Common Cold; Eosinophil Cationic Protein; Humans; Inflammation; Methacholine Chloride; Middle Aged; Nitric Oxide; Peak Expiratory Flow Rate; Respiratory Sounds; Young Adult | 2007 |
Conversion of Th17-type into Th2-type inflammation by acetyl salicylic acid via the adenosine and uric acid pathway in the lung.
Topics: Adenosine; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Lung; Mice; Mice, Inbred C57BL; Th17 Cells; Th2 Cells; Uric Acid | 2010 |
Involvement of A1 adenosine receptors in altered vascular responses and inflammation in an allergic mouse model of asthma.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Administration, Inhalation; Aerosols; Ambrosia; Animals; Antigens, Plant; Aorta; Asthma; Blotting, Western; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Plethysmography, Whole Body; Polymerase Chain Reaction; Receptor, Adenosine A1; RNA, Messenger; Vasodilation | 2010 |
Disparity in FcεRI-induced degranulation of primary human lung and skin mast cells exposed to adenosine.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Asthma; Bronchoconstriction; Bronchoconstrictor Agents; Cell Degranulation; Gene Expression; Humans; Lung; Mast Cells; Organ Specificity; Receptor, Adenosine A3; Receptors, IgE; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin | 2011 |
Comparison of bronchial hyperresponsiveness to methacholine and adenosine and airway inflammation markers in patients with suspected asthma.
Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Biomarkers; Breath Tests; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Eosinophils; Exhalation; Female; Humans; Inflammation; Leukocyte Count; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Sensitivity and Specificity; Sputum; Young Adult | 2011 |
Pharmacological characterization of adenosine receptors on isolated human bronchi.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Asthma; Bronchi; Bronchoconstriction; Capsaicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organ Culture Techniques; Receptor, Adenosine A1; Sensory System Agents; Vasodilator Agents | 2011 |
Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma.
Topics: Adenosine; Adult; Asthma; Breath Tests; Case-Control Studies; Female; Humans; Male; Reproducibility of Results; Respiratory Function Tests; Saliva | 2002 |
Characterization of adenosine receptor(s) involved in adenosine-induced bronchoconstriction in an allergic mouse model.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic Agonists; Adrenergic Antagonists; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Hypersensitivity; Lung; Male; Mice; Mice, Inbred BALB C; Phenethylamines; Pyridines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasodilator Agents | 2003 |
A patient with chaotic atrial tachycardia.
Topics: Abnormalities, Multiple; Adenosine; Anti-Asthmatic Agents; Asthma; Bronchiolitis; Combined Modality Therapy; Diagnosis, Differential; Dyspnea; Electroencephalography; Emergencies; Female; Fluid Therapy; Furosemide; Heart Failure; Heart Septal Defects, Atrial; Humans; Infant; Procainamide; Recurrence; Tachycardia; Tachycardia, Ectopic Atrial | 2003 |
IL-13 and adenosine: partners in a molecular dance?
Topics: Adenosine; Animals; Asthma; Humans; Inflammation; Interleukin-13; Lung Injury; Mice; Models, Biological; Signal Transduction; T-Lymphocytes | 2003 |
Adenosine levels in the exhaled breath condensate: a potential surrogate marker of airway inflammation.
Topics: Adenosine; Asthma; Biomarkers; Breath Tests; Humans | 2003 |
Selectively enhanced sensitivity of bronchoalveolar lavage fluid (BALF) mast cells to IgE dependent stimulation in mild asthmatics.
Topics: Adenosine; Adult; Antibodies, Anti-Idiotypic; Asthma; Bronchoalveolar Lavage Fluid; Bronchoscopes; Calcimycin; Colon; Dose-Response Relationship, Immunologic; Female; Forced Expiratory Volume; Histamine Release; Humans; Immunoglobulin E; Ionophores; Lung; Male; Mast Cells; Middle Aged; Sensitivity and Specificity; Severity of Illness Index; Vasodilator Agents | 2003 |
Dust mite-induced asthma in cynomolgus monkeys.
Topics: Adenosine; Aerosols; Allergens; Animals; Asthma; Bronchial Provocation Tests; Cytokines; Disease Models, Animal; Dust; Histamine; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immunization; Immunoglobulin E; Immunoglobulin G; Lung; Macaca fascicularis; Mites; Respiratory Function Tests; Respiratory Hypersensitivity; Respiratory System; Th2 Cells; Time Factors | 2004 |
[Replacement of ACTH in certain cases by adenosine triphosphoric acid].
Topics: Adenosine; Adenosine Triphosphate; Adrenocorticotropic Hormone; Asthma; Gout; Polyphosphates; Replantation; Rheumatic Diseases | 1952 |
[Effect of adenosine and anti-IgE antibody on histamine release from mast cells in BALF of asthma patients].
Topics: Adenosine; Adult; Antibodies, Anti-Idiotypic; Asthma; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Female; Histamine Release; Humans; Male; Mast Cells; Middle Aged | 2003 |
Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: an A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Asthma; B-Lymphocytes; Cell Communication; Cells, Cultured; Coculture Techniques; Cytokines; Humans; Immunoglobulin E; Interleukin-13; Interleukin-4; Mast Cells; Receptor, Adenosine A2B; RNA, Messenger; Th2 Cells; Up-Regulation | 2004 |
Adenosine up-regulation of the mucin gene, MUC2, in asthma.
Topics: Adenosine; Asthma; ErbB Receptors; Humans; Ion Channels; Mucin-2; Mucins; Niflumic Acid; Phosphorylation; Receptors, Purinergic P1; Respiratory Mucosa; Trachea; Transcriptional Activation; Up-Regulation | 2004 |
Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. 1983.
Topics: Adenosine; Administration, Inhalation; Airway Resistance; Asthma; Case-Control Studies; Guanosine; History, 20th Century; Humans | 2004 |
A1 antagonism in asthma: better than coffee?
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Asthma; Coffee; Humans; Lung; Lung Injury; Receptor, Adenosine A1; Signal Transduction | 2005 |
Mast cell degranulation after endobronchial adenosine challenge.
Topics: Adenosine; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Humans; Mast Cells | 2005 |
The Quintiles Prize Lecture 2004. The identification of the adenosine A2B receptor as a novel therapeutic target in asthma.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Humans; Mast Cells | 2005 |
A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Dust; Histamine; Mites; Phosphodiesterase Inhibitors; Purines; Rabbits; Radioligand Assay; Receptor, Adenosine A1 | 2005 |
Role of adenosine in airway inflammation in an allergic mouse model of asthma.
Topics: Adenosine; Animals; Asthma; beta-N-Acetylhexosaminidases; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chemokines, CC; Disease Models, Animal; Eosinophil Peroxidase; Immunization; Inflammation; Inflammation Mediators; Male; Mast Cells; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Pollen; Respiratory System | 2006 |
Mast cell numbers in airway smooth muscle and PC20AMP in asthma and COPD.
Topics: Adenosine; Adolescent; Adult; Aged; Asthma; Biopsy; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoscopy; Cell Count; Female; Forced Expiratory Volume; Humans; Male; Mast Cells; Middle Aged; Muscle, Smooth; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Tryptases | 2007 |
Methotrexate regulates the expression of glucocorticoid receptor alpha and beta isoforms in normal human peripheral mononuclear cells and human lymphocyte cell lines in vitro.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Asthma; Autoimmune Diseases; Drug Synergism; Gene Expression Regulation; Humans; Immunosuppressive Agents; Inflammation; Jurkat Cells; Lipopolysaccharides; Lymphocytes; Methotrexate; Protein Isoforms; Receptors, Glucocorticoid; Theobromine; Vasodilator Agents | 2007 |
Effect of a specific and selective A(2B) adenosine receptor antagonist on adenosine agonist AMP and allergen-induced airway responsiveness and cellular influx in a mouse model of asthma.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Administration, Inhalation; Aerosols; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Plethysmography; Purines; Pyrazoles | 2007 |
Adenosine receptors: novel targets for drug development in allergic rhinitis.
Topics: Adenosine; Adenosine A3 Receptor Antagonists; Asthma; Chronic Disease; Humans; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Rhinitis; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Signal Transduction | 2007 |
Adenosine for salbutamol-induced supraventricular tachycardia.
Topics: Adenosine; Albuterol; Anti-Arrhythmia Agents; Asthma; Bronchodilator Agents; Humans; Male; Tachycardia, Supraventricular | 2007 |
The safety and tolerability of adenosine in patients with obstructive airways disease.
Topics: Adenosine; Aged; Aged, 80 and over; Asthma; Cohort Studies; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Spirometry | 2008 |
In vivo adenosine A(2B) receptor desensitization in guinea-pig airway smooth muscle: implications for asthma.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Asthma; Base Sequence; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Hypersensitivity; Isoproterenol; Muscle, Smooth; Purines; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Elevated expression of adenosine A1 receptor in bronchial biopsy specimens from asthmatic subjects.
Topics: Adenosine; Administration, Inhalation; Asthma; Biomarkers; Biopsy, Needle; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Immunohistochemistry; Male; Prognosis; Receptor, Adenosine A1; Reference Values; Respiratory Function Tests; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Up-Regulation | 2008 |
Mast cell activation after adenosine inhalation challenge in patients with bronchial asthma.
Topics: Adenosine; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Case-Control Studies; Dinoprost; Female; Humans; Inflammation Mediators; Male; Mast Cells; Reference Values; Sensitivity and Specificity | 2008 |
Adenosine-mediated alteration of vascular reactivity and inflammation in a murine model of asthma.
Topics: Acetylcholine; Adenosine; Administration, Inhalation; Allergens; Ambrosia; Animals; Aorta; Asthma; Disease Models, Animal; Dose-Response Relationship, Drug; Flavins; Inflammation; Inflammation Mediators; Lung; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Plant Proteins; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Vasodilation; Vasodilator Agents; Xanthines | 2008 |
Adenosine-induced respiratory arrest in an asthmatic patient.
Topics: Adenosine; Aged; Asthma; Exercise Test; Female; Humans; Respiratory Insufficiency; Vasodilator Agents | 2008 |
Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Asthma; Bronchial Hyperreactivity; Female; Hexosaminidases; Lung; Mast Cells; Mice; Mice, Inbred C57BL; Receptor, Adenosine A3 | 2008 |
Universal adenosine receptor antagonism is neither necessary nor desirable with xanthine antiasthmatics.
Topics: Adenosine; Airway Resistance; Animals; Asthma; Central Nervous System; Diuresis; Dose-Response Relationship, Drug; Humans; Mice; Natriuresis; Neural Inhibition; Phosphodiesterase Inhibitors; Rats; Receptors, Cell Surface; Receptors, Purinergic; Seizures; Theophylline | 1982 |
Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects.
Topics: Adenosine; Adolescent; Adult; Aged; Airway Resistance; Asthma; Bronchi; Constriction, Pathologic; Cyclic AMP; Forced Expiratory Volume; Guanosine; Humans; Middle Aged; Respiratory Therapy; Sodium Chloride; Theophylline | 1983 |
Adenosine as a bronchoconstrictor mediator in asthma and its antagonism by methylxanthines.
Topics: Adenosine; Asthma; Bronchi; Humans; Immunoglobulin E; Mast Cells; Theophylline; Xanthines | 1984 |
Adenosine antagonism as an alternative mechanism of action of methylxanthines in asthma.
Topics: Adenosine; Adenosine Monophosphate; Airway Resistance; Asthma; Bronchi; Dose-Response Relationship, Drug; Guanosine; Histamine; Humans; Inosine; Theophylline | 1983 |
Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline.
Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Drug Antagonism; Female; Forced Expiratory Volume; Histamine; Humans; Male; Theophylline | 1984 |
Adenosine antagonism, a less desirable characteristic of xanthine asthma drugs?
Topics: Adenosine; Animals; Asthma; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Rats; Theophylline; Xanthines | 1981 |
Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Anti-Asthmatic Agents; Asthma; Calcium; Cyclic AMP; Humans; Inositol Phosphates; Interleukin-8; Mast Cells; Receptors, Purinergic P1; Tumor Cells, Cultured; Xanthines | 1995 |
Bronchospasm after intravenous administration of adenosine in a patient with asthma.
Topics: Adenosine; Adolescent; Asthma; Bronchial Spasm; Bronchodilator Agents; Female; Humans; Infusions, Intravenous; Tachycardia, Supraventricular | 1994 |
Adenosine-induced bronchoconstriction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: evidence for an inducible adenosine A1 receptor.
Topics: Adenosine; Animals; Asthma; Binding, Competitive; Bronchoconstriction; Disease Models, Animal; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Purinergic P1; Trachea; Vaccination; Xanthines | 1994 |
Bronchospasm induced by intravenous adenosine.
Topics: Adenosine; Aged; Asthma; Bronchial Spasm; Contraindications; Humans; Injections, Intravenous; Male; Middle Aged; Tachycardia, Supraventricular | 1994 |
Adenosine-induced bronchoconstriction in conscious hyperresponsive and sensitized guinea pigs.
Topics: Adenosine; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol; Guinea Pigs; Immunization; Male; Ovalbumin; Ozone; Platelet Activating Factor | 1994 |
Adenosine in bronchoalveolar lavage fluid in asthma.
Topics: Adenosine; Adult; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoscopy; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Middle Aged; Nebulizers and Vaporizers; Reference Values; Smoking; Spirometry | 1993 |
Airway hyper- or hyporeactivity to inhaled spasmogens 24 h after ovalbumin challenge of sensitized guinea-pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Administration, Inhalation; Airway Resistance; Animals; Asthma; Atropine; Bronchial Spasm; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Methacholine Chloride; Ovalbumin; Plethysmography, Whole Body; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Asthma. Blocking adenosine with antisense.
Topics: Adenosine; Animals; Asthma; Gene Expression; Humans; Lung; Oligonucleotides, Antisense; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1 | 1997 |
DNA antisense therapy for asthma in an animal model.
Topics: Adenosine; Administration, Inhalation; Animals; Antigens, Dermatophagoides; Asthma; Bronchial Hyperreactivity; Cross-Over Studies; Disease Models, Animal; DNA, Antisense; Glycoproteins; Humans; Lung; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Respiratory Function Tests | 1997 |
[Anomalous reaction to adenosine of lymphocytes from patients with atopic bronchial asthma. Is it a link in pathogenesis or a compensatory reaction?].
Topics: Adenosine; Asthma; CD4 Antigens; CD8 Antigens; Cytotoxicity, Immunologic; Humans; Lymphocyte Activation; T-Lymphocytes | 1996 |
A1 adenosine receptor-mediated Ins(1,4,5)P3 generation in allergic rabbit airway smooth muscle.
Topics: Adenosine; Airway Resistance; Allergens; Animals; Asthma; Bronchi; Dust; Estrenes; Immunoglobulin E; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lung Compliance; Mites; Muscle Contraction; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Pyrrolidinones; Rabbits; Receptors, Purinergic P1; Respiratory Hypersensitivity | 1998 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Using intravenous adenosine in asthmatics.
Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Contraindications; Emergencies; Evidence-Based Medicine; Female; Humans; Infusions, Intravenous; Risk Factors; Tachycardia, Supraventricular | 2001 |
Role of adenosine in asthma.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Bronchodilator Agents; Dogs; Humans; Lung; Mast Cells; Mice; Rats; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Theophylline; Xanthines | 1996 |
Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice.
Topics: Adenosine; Adenosine Deaminase; Animals; Asthma; Bronchi; Bronchitis; Cell Count; Chemokine CCL7; Cytokines; Digestive System; Eosinophils; Lung; Macrophages, Alveolar; Male; Mice; Mice, Mutant Strains; Monocyte Chemoattractant Proteins; Pneumonia; Receptors, Purinergic P1; Respiratory Mucosa; RNA, Messenger; Signal Transduction | 2001 |
Gene expression profiling in inflammatory airway disease associated with elevated adenosine.
Topics: Adenosine; Adenosine Deaminase; Animals; Asthma; Chemokine CCL7; Cytokines; Endothelial Growth Factors; Eosinophils; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Lung; Lymphokines; Mice; Mice, Transgenic; Monocyte Chemoattractant Proteins; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
[Image analysis of airway remodeling and responsiveness in asthmatic guinea pig].
Topics: Acetylcholine; Adenosine; Aminophylline; Animals; Asthma; Guinea Pigs; Heparin; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Vasodilator Agents | 2001 |
Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat.
Topics: Adenosine; Allergens; Animals; Anti-Inflammatory Agents; Asthma; Blood Pressure; Budesonide; Dose-Response Relationship, Drug; Inflammation; Lung; Male; Ovalbumin; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred BN; Receptor, Adenosine A2A; Triazines; Triazoles; Vascular Resistance | 2002 |
Adenosine-induced bronchoconstriction in an allergic rabbit model: antagonism by theophylline aerosol.
Topics: Adenosine; Aerosols; Anesthesia; Animals; Asthma; Bronchial Hyperreactivity; Histamine; Pollen; Rabbits; Respiratory Hypersensitivity; Theophylline | 1992 |
Isolated bronchi from asthmatics are hyperresponsive to adenosine, which apparently acts indirectly by liberation of leukotrienes and histamine.
Topics: Adenosine; Asthma; Bronchi; Bronchial Hyperreactivity; Female; Histamine Release; Humans; In Vitro Techniques; Leukotrienes; Male; Middle Aged | 1992 |
[Mechanisms of the joint action of cortisol and adenosine on peripheral blood lymphocytes in bronchial asthma].
Topics: Adenosine; Asthma; Cells, Cultured; Culture Media; Cyclic AMP; Humans; Hydrocortisone; In Vitro Techniques; Lymphocytes; Stimulation, Chemical | 1991 |
Effects of NZ-107 on tracheal responses to adenosine in the guinea pig.
Topics: Adenosine; Aminophylline; Animals; Asthma; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Pyridazines; Trachea | 1991 |
Bronchial challenge with adenosine causes the release of serum neutrophil chemotactic factor in asthma.
Topics: Adenosine; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Chemotaxis, Leukocyte; Female; Humans; Interleukin-8; Male; Middle Aged; Neutrophils; Theophylline | 1991 |
[Studies of adenosine inhalation in asthmatic patients].
Topics: Adenosine; Administration, Inhalation; Adult; Aged; Asthma; Bronchi; Cyclic AMP; Female; Humans; Leukotrienes; Male; Middle Aged; Thromboxane B2 | 1990 |
Role of purinergic system in tracheobronchial reactivity of healthy and bronchopathic subjects.
Topics: Adenosine; Adolescent; Adult; Aged; Albuterol; Aminophylline; Asthma; Bronchi; Bronchitis; Bronchodilator Agents; Child; Drug Combinations; Female; Forced Expiratory Volume; Humans; Male; Metaproterenol; Middle Aged; Receptors, Purinergic; Theophylline; Trachea | 1990 |
Superoxide generation and its modulation by adenosine in the neutrophils of subjects with asthma.
Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Asthma; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides | 1989 |
Asthmatic patients have neutrophils that exhibit diminished responsiveness to adenosine.
Topics: 2-Chloroadenosine; Adenosine; Asthma; Calcimycin; Cytochalasin B; Dinoprostone; Dose-Response Relationship, Drug; Humans; Isoproterenol; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides | 1989 |
Adenosine revisited.
Topics: Adenosine; Arrhythmias, Cardiac; Asthma; Coronary Circulation; Humans; Kidney | 1985 |
Adenosine-induced bronchoconstriction in asthma: role of mast cell-mediator release.
Topics: Adenosine; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chemotactic Factors; Cromolyn Sodium; Cyclic AMP; Female; Forced Expiratory Volume; Histamine; Humans; Interleukin-8; Male; Mast Cells; Middle Aged | 1985 |
On the mechanism of action of theophylline and caffeine.
Topics: Adenosine; Asthma; Caffeine; Calcium; Cyclic AMP; Humans; Muscle Contraction; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Adenosine-induced bronchoconstriction in asthma. Role of parasympathetic stimulation and adrenergic inhibition.
Topics: Adenosine; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Constriction, Pathologic; Female; Histamine; Histamine Antagonists; Humans; Ipratropium; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Receptors, Adrenergic, beta; Respiratory Function Tests; Vagus Nerve | 1985 |
The bronchial effects of adenosine in the rat.
Topics: Adenosine; Anesthesia; Animals; Asthma; Bronchi; Dose-Response Relationship, Drug; Hexamethonium Compounds; Injections, Intravenous; Pressure; Rats; Receptors, Cell Surface; Receptors, Purinergic; Xanthines | 1986 |
Adenosine-induced bronchoconstriction: premedication with chlorpheniramine and nedocromil sodium.
Topics: Adenosine; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Chlorpheniramine; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Nedocromil; Quinolines | 1986 |
Effect of nedocromil sodium on adenosine- and methacholine-induced bronchospasm in asthma.
Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Nedocromil; Quinolines | 1987 |
[Capnography-controlled adenosine loading in chronic respiratory tract diseases in childhood].
Topics: Adenosine; Aerosols; Asthma; Carbon Dioxide; Child; Chronic Disease; Female; Humans; Immunoglobulin E; Lung Diseases, Obstructive; Male; Respiratory Function Tests; Rhinitis, Allergic, Perennial | 1988 |
[The role of vagal reflex on adenosine-induced bronchoconstriction in asthma].
Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Female; Humans; Male; Reflex; Vagus Nerve | 1988 |
Effect of adenosine and pertussis vaccine on lymphocyte response in vitro to phytohemagglutinin in asthmatic and non-asthmatic subjects.
Topics: Adenosine; Adult; Asthma; Dose-Response Relationship, Immunologic; Humans; Immune Tolerance; Lymphocyte Activation; Pertussis Vaccine; Phytohemagglutinins | 1988 |
Contribution of inflammatory mediators to the immediate asthmatic reaction.
Topics: Adenosine; Allergens; Asthma; Bronchi; Bronchial Spasm; Humans; Mast Cells; Prostaglandin D2; Prostaglandins D; Skin | 1987 |
Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Inosine; Kinetics; Methacholine Chloride; Methacholine Compounds | 1986 |
Mediators and asthma.
Topics: Adenosine; Asthma; Bradykinin; Bronchial Spasm; Chemotactic Factors; Chemotaxis, Leukocyte; Histamine; Humans; Lipoxygenase; Nerve Tissue Proteins; Platelet Activating Factor; Prostaglandins; SRS-A | 1985 |
The effect of dipyridamole on histamine- and adenosine-induced bronchoconstriction in normal and asthmatic subjects.
Topics: Adenosine; Administration, Intranasal; Adult; Asthma; Bronchi; Dipyridamole; Female; Histamine; Humans; Infusions, Parenteral; Male; Middle Aged | 1985 |