Page last updated: 2024-08-24

adenosine and Asthma

adenosine has been researched along with Asthma in 184 studies

Research

Studies (184)

TimeframeStudies, this research(%)All Research%
pre-199045 (24.46)18.7374
1990's37 (20.11)18.2507
2000's70 (38.04)29.6817
2010's22 (11.96)24.3611
2020's10 (5.43)2.80

Authors

AuthorsStudies
Fan, L; Shen, F; Sun, D; Wang, Z; Yang, H1
Dong, J; Huang, X; Qin, J; Tang, W; Tang, Z; Teng, F; Wang, S; Wei, Y; Wuniqiemu, T; Zhou, Y; Zhu, X1
Li, HM; Li, SM; Li, XM; Mo, BW; Xiao, B; Yang, J1
Godinho, RO; Jackson, EK; Pacini, ESA; Satori, NA1
Deng, K; Fang, XM; Huang, D; Li, WM; Liu, D; Liu, L; Liu, Y; Luo, FM; Oliver, BG; Wan, HJ; Wang, G; Wang, J; Wang, L; Zhang, HP; Zhang, L; Zhang, X1
Li, L; Xu, L; Yan, C; Zhou, L1
Chen, ZH; Du, J; Jia, LX; Liu, TT; Piao, CM; Shen, HH; Wang, YL; Zhang, J; Zhang, Z; Zheng, S1
Brogan, R; Ford, TJ; Morrow, A1
Almqvist, G; Eriksson, L; Leaker, BR; Lindgren, S; O'Connor, B; Singh, D; Young, B1
Chen, D; Li, H; Li, J; Lu, T; Luo, X; Ma, R; Sun, W; Wen, W; Xu, R1
Choi, H; Jang, S; Kim, H; Kim, SM; Kim, TD; Kim, VN; Lee, JW; Lee, YS1
Armoni Domany, K; Ater, D; Golan-Lagziel, T; Mandelberg, A; Wolfson, Y1
Boudewijn, IM; Cox, CA; Frijlink, HW; Hagedoorn, P; Lexmond, AJ; Schokker, S; Ten Hacken, NHT; van den Berge, M; Vonk, JM; Vroegop, SJ1
Carlsen, KH; Coates, AL; Cockcroft, DW; Culver, BH; de Jongh, FHC; Diamant, Z; Gauvreau, GM; Hall, GL; Hallstrand, TS; Horvath, I; Joos, G; Kaminsky, DA; Laube, BL; Leuppi, JD; Sterk, PJ; Wanger, J1
Boudewijn, IM; Cox, CA; Farenhorst, MP; Frijlink, HW; Hagedoorn, P; Kerstjens, HAM; Lexmond, AJ; Schokker, S; Ten Hacken, NHT; van den Berge, M; Vonk, JM; Vroegop, SJ1
Chen, H; Chen, X; Chen, Y; He, D; Shen, L; Wang, J; Xia, C; Yan, X; Zeng, M; Zhu, D1
Borah, P; Deb, PK; Deka, S; Mailavaram, RP1
Butler, K; Maya, J; Teng, R1
Cui, Y; Erb, KJ; Gantner, F; Mayer, H; Schuetz, JD; Schymeinsky, J; Tilp, C; Tomsic, C; Wollin, L1
Cicala, C; Ialenti, A1
Hall, M; Pencharz, D; Quigley, AM; Wagner, TL1
Bult, W; de Boer, AH; Frijlink, HW; Hagedoorn, P; Lexmond, AJ; ten Hacken, NH; van der Wiel, E1
Dekel, O; Rudich, N; Sagi-Eisenberg, R1
Alessandrini, F; Behrendt, H; Ernst, D; Ferreira, F; Frank, U; Gilles, S; Gutermuth, J; Hauser, M; Oeder, S; Ohnmacht, C; Ring, J; Schmidt-Weber, C; Schmitt-Kopplin, P; Traidl-Hoffmann, C; Wimmer, M; Winkler, JB1
Aryan, Z; Rezaei, N1
Linden, J; Pei, H1
Gao, QZ; Wei, J; Yu, WQ1
Benfatto, GT; Polosa, R1
Barnard, A; Mantell, SJ; Stuart, EF; Trevethick, MA; Wright, KN; Yeadon, M1
Polosa, R1
Wilson, CN1
Derom, E; Engelstätter, R; Joos, GF; Kaufman, JM; Louis, R; Tiesler, C1
Notghi, A; Smith, NB; Sundram, F1
Boucher, RC; Boysen, G; Collins, LB; Esther, CR; Ghio, AJ; Olsen, BM; Swenberg, JW1
Ansari, HR; Batchelor, TP; Dey, RD; Ledent, C; Mustafa, SJ; Nadeem, A; Ponnoth, DS1
Brown, R; Mustafa, SJ; Nadeem, A; Page, CP; Spina, D; Wilson, CN1
Caruso, M; Polosa, R; Tringali, G; Varani, K1
Barrett, RJ; Busse, WW; Katial, RK; Lockey, RF; McFadden, ER; Murray, JJ; Pixton, GC; Schwartz, LB; Weiler, JM1
Björnsson, E; Eriksson, BM; Hedenström, H; Högman, M; Janson, C; Lúdvíksdóttir, D; Venge, P1
Gyu Jeon, S; Kim, YK; Kim, YS; Moon, HG; Oh, SY; Song Gho, Y; Tae, YM; Zhu, Z1
Mustafa, SJ; Nadeem, A; Ponnoth, DS; Tilley, S1
Gomez, G; Schwartz, LB; Zhao, W1
Fernández-Nieto, M; Madero, MF; Manso, L; Ruiz-García, M; Sastre, J1
Calzetta, L; Cazzola, M; Facciolo, F; Matera, MG; Page, CP; Rendina, EA; Spina, D1
Barranco, P; Bobolea, I; Calderon, O; Guillén, D; Lopez-Carrasco, V; Quirce, S1
Barát, E; Csoma, Z; Herjavecz, I; Horváth, I; Huszár, E; Molnár Világos, G; Vass, G; Vizi, E1
Fan, M; Mustafa, SJ; Qin, W1
Polosa, R; Spicuzza, L1
Lin, Y; Wang, Z; Zhou, X; Zhu, Y1
Ali, S; Gouin, S1
Fozard, JR1
Grünig, G1
Bonfiglio, C; Polosa, R; Spicuzza, L1
Di Maria, GU; Polosa, R; Spicuzza, L1
Chen, P; He, S; Xie, H1
Avital, A; Bardach, E; Berkman, N; Breuer, R; Godfrey, S; Springer, C1
Ehrmann, D; Hooker, JL; Kukoly, C; Nyce, J; Salleng, K; Sandrasagra, A; Shibata, Y; Van Scott, MR; Westergaard, G1
Holgate, ST; Rorke, S1
de Meer, G; Marks, GB; Postma, DS1
BAVAY, J; GRENIER, J; LUTIER, F1
Ennis, M; Heaney, LG; Livingston, M1
Chen, P; He, SH; Xie, H1
Biaggioni, I; Feoktistov, I; Goldstein, AE; Matafonov, A; Ryzhov, S; Zeng, D1
Basbaum, C; Fahy, J; Gallup, M; Khong, A; Maltseva, I; McNamara, N; Sucher, A1
Cushley, MJ; Holgate, ST; Tattersfield, AE4
Boucher, RC; Tilley, SL1
Joos, G; Pauwels, R; Van Schoor, J1
Lauretta, D; Polosa, R1
Holgate, ST4
Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN1
Joos, GF1
Fan, M; Jamal Mustafa, S1
Blackburn, MR; Mohsenin, A1
Arcidiacono, G; Polosa, R; Russo, C1
Di Maria, G; Polosa, R; Spicuzza, L1
Caruso, M; Holgate, ST; Polosa, R1
Liesker, JJ; Postma, DS; Rutgers, SR; Ten Hacken, NH; Timens, W; Zeinstra-Smith, M1
Alvarez, C; Ferreira, A; Gatica, H; Goecke, IA; Henríquez, J; Molina, ML; Salas, K1
Alam, M; Burki, NK; Lee, LY1
Belardinelli, L; Fan, M; Mustafa, SJ; Nadeem, A; Zeng, D; Zhong, H1
Matera, MG; Polosa, R1
Hylkema, MN; Postma, DS; van den Berge, M; Versluis, M1
Hammer, J; Newth, CJ; Trachsel, D1
Allman, KC; Chan, M; Couthino, B; van Gaal, WJ1
Adinolfi, B; Blandizzi, C; Breschi, MC; Calderone, V; Camici, M; Fogli, S; Martinelli, C; Martinotti, E; Nieri, P1
Dip, RG1
Brown, RA; Clarke, GW; Coote, JE; Denyer, JC; Hurle, MJ; Ledbetter, CL; Murdoch, RD; O'Connor, BJ; Page, CP; Savage, TJ; Simcock, DE; Spina, D1
Anderson, SD1
Bochenek, G; Gielicz, A; Nizankowska, E; Szczeklik, A1
Mustafa, SJ; Nadeem, A; Ponnoth, DS1
Brown, RA; Page, CP; Spina, D1
Patton, JW; Sharma, GK1
Chason, KD; Deshpande, DA; Fredholm, BB; Hua, X; Penn, RB; Tilley, SL1
Pauwels, R1
Jenne, JW1
Persson, CG3
Cushley, MJ; Holgate, ST; Mann, JS2
Erjefält, I; Karlsson, JA; Persson, CG1
Martin, JG1
Biaggioni, I; Feoktistov, I2
DeGroff, CG; Silka, MJ1
Ali, S; Metzger, WJ; Mustafa, SJ2
Drake, I; Richards, R; Routledge, PA1
Joos, GF; Kips, JC; Pauwels, RA1
Broadley, KJ; Thorne, JR1
Ali, S; Driver, AG; Kukoly, CA; Mustafa, SJ1
Broadley, KJ; Lewis, CA1
Richardson, PJ1
Metzger, WJ; Nyce, JW1
Gavrilova, EV; Makarkov, AI; Poriadin, GV; Salmasi, ZhM1
Carpentier, PJ; Drajesk, JF; Joos, GF; Kips, JC; Pauwels, RA; Van Schoor, J1
Crimi, N; Mistretta, A; Polosa, R1
Holgate, ST; Polosa, R1
Dent, G; Rabe, KF1
Church, MK; Coward, WR; Sagara, H1
Abebe, W; Mustafa, SJ1
Ennis, M; Forsythe, P1
Fozard, JR; Hannon, JP1
Joos, GF; Pauwels, RA; Van Schoor, J1
Lumsden, G; Terry, P1
Banerjee, SK; Blackburn, MR; Chunn, JL; Colasurdo, GN; Young, HW1
Leonard, SA; Li, Y; Mannion, JC; Nyce, JW; Sandrasagra, A; Tang, L; Teng, K1
Banerjee, SK; Blackburn, MR; Volmer, JB; Young, HW1
He, Q; Yao, W; Zhang, X1
Ellis, KM; Fozard, JR; Mazzoni, L; Tigani, B; Villela Dantas, MF1
Holgate, ST; Polosa, R; Rorke, S1
Björck, T; Dahlén, SE; Gustafsson, LE1
Crimi, N; Mistretta, A; Oliveri, R; Palermo, F; Polosa, R; Settinieri, I1
Abazova, FI; Alieva, NG; Dukhanin, AS; Ogurtsov, SI; Omel'ianovskiĭ, VV; Sergeev, PV1
Joos, G; Kips, J; Pauwels, R1
Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A1
Church, MK; Holgate, ST; Polosa, R2
Driver, AG; Kukoly, CA; Metzger, WJ; Mustafa, SJ1
Diamond, L; Küng, M1
Akisawa, T; Nakagami, K; Narushima, M; Noguchi, E; Suzuki, H; Tanaka, K1
Finnerty, JP; Holgate, ST; Polosa, R1
Schwartz, LB1
Church, MK; Ng, WH; Polosa, R1
Crimi, N; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C1
Carapella, N; Filippelli, A; Loffreda, A; Marmo, E; Matera, MG; Montanaro, C; Santagata, A; Servodio, R; Susanna, V1
Steinberg, TH1
Church, MK; Holgate, ST1
Crimi, N; Distefano, SM; Mistretta, A; Oliveri, R; Palermo, F; Polosa, R; Vancheri, C1
Easton, J; Goldberg, B; Lad, P; Meltzer, S1
Borish, L; Joseph, B; Rocklin, RE; Sustiel, AM1
Karlsson, JA1
Crimi, N; Maccarrone, C; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C2
Erjefält, I; Gustafsson, B; Persson, CG1
Cushley, MJ; Holgate, ST1
Fredholm, BB1
Andersson, KE; Kjellin, G; Persson, CG1
Pauwels, R; van der Straeten, M1
Brancatisano, M; Brusasco, V; Crimi, E; Crimi, P; Losurdo, E2
Cacopardo, B; Crimi, N; Mistretta, A; Oliveri, R; Palermo, F; Vancheri, C1
Church, MK; Cushley, MJ; Featherstone, RL; Holgate, ST; Mann, JS1
Barnes, PJ2
Joos, G; Pauwels, R; Van der Straeten, M1
Bittera, I; Gyurkovits, K; Papp, A; Rápó, J1
Ma, JY1
Larsson, K; Sollevi, A1
Church, MK; Cushley, MJ; Holgate, ST; Mann, JS1
Chaperon, EA; Hiratani, M; McCall, MK; Townley, RG1
Church, MK; Cushley, MJ; Holgate, ST; Hughes, P; Mann, JS1
Bradding, P; Hardy, CC; Holgate, ST; Robinson, C1
Cushley, MJ; Holgate, ST; Mann, JS; Renwick, AG1
Wasserman, SI1
Holgate, ST; Mann, JS1
Cushley, MJ; Holgate, ST; Tallant, N1

Reviews

58 review(s) available for adenosine and Asthma

ArticleYear
Extracellular cAMP-Adenosine Pathway Signaling: A Potential Therapeutic Target in Chronic Inflammatory Airway Diseases.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenosine; Adenosine Monophosphate; Asthma; Humans; Receptors, Adrenergic; Signal Transduction

2022
Emerging role of N6-methyladenosine RNA methylation in lung diseases.
    Experimental biology and medicine (Maywood, N.J.), 2022, Volume: 247, Issue:20

    Topics: Adenosine; Asthma; Humans; Lung Diseases; Lung Neoplasms; Methylation; RNA; RNA, Messenger

2022
P1 Receptor Agonists/Antagonists in Clinical Trials - Potential Drug Candidates of the Future.
    Current pharmaceutical design, 2019, Volume: 25, Issue:26

    Topics: Adenosine; Asthma; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Ligands; Neoplasms; Parkinson Disease; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Pyrazoles; Receptors, Purinergic P1

2019
Toll-like receptors as targets for allergen immunotherapy.
    Current opinion in allergy and clinical immunology, 2015, Volume: 15, Issue:6

    Topics: Adenosine; Animals; Anti-Allergic Agents; Asthma; Clinical Trials as Topic; Desensitization, Immunologic; Humans; Lipid A; Molecular Targeted Therapy; Oligodeoxyribonucleotides; Oligonucleotides; Phenylacetates; Rhinitis, Allergic; Toll-Like Receptors; Vaccines

2015
Treating lung inflammation with agonists of the adenosine A2A receptor: promises, problems and potential solutions.
    British journal of pharmacology, 2008, Volume: 155, Issue:4

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Inflammation; Lung; Pulmonary Disease, Chronic Obstructive

2008
Adenosine receptors and asthma in humans.
    British journal of pharmacology, 2008, Volume: 155, Issue:4

    Topics: Adenosine; Animals; Anti-Asthmatic Agents; Asthma; Clinical Trials as Topic; Drug Delivery Systems; Drug Design; Humans; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction

2008
Adenosine receptors and asthma.
    Handbook of experimental pharmacology, 2009, Issue:193

    Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Humans; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1

2009
Adenosine and adenosine receptors: their contribution to airway inflammation and therapeutic potential in asthma.
    Current medicinal chemistry, 2009, Volume: 16, Issue:29

    Topics: Adenosine; Anti-Asthmatic Agents; Asthma; Drug Delivery Systems; Humans; Inflammation; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1

2009
The role of adenosine as a novel bronchoprovocant in asthma.
    Current opinion in allergy and clinical immunology, 2003, Volume: 3, Issue:1

    Topics: Adenosine; Administration, Inhalation; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Humans

2003
[The effects of adenosine, interleukin-1 and theophylline on the expression of A2 adenosine receptor mRNAs in peripheral blood mononuclear cells from asthmatic patients].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 2001, Volume: 32, Issue:2

    Topics: Adenosine; Adolescent; Adult; Asthma; Female; Humans; Interleukin-1; Leukocytes, Mononuclear; Male; Middle Aged; Receptors, Purinergic P1; RNA, Messenger; Theophylline

2001
The case for a role for adenosine in asthma: almost convincing?
    Current opinion in pharmacology, 2003, Volume: 3, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Animals; Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Bronchodilator Agents; Humans; Receptors, Adenosine A2; Theophylline

2003
Research applications and implications of adenosine in diseased airways.
    Trends in pharmacological sciences, 2003, Volume: 24, Issue:8

    Topics: Adenosine; Administration, Inhalation; Animals; Asthma; Bronchoconstriction; Diagnosis, Differential; Humans; Inflammation; Pulmonary Disease, Chronic Obstructive; Vasodilator Agents

2003
Targeting adenosine receptors: novel therapeutic targets in asthma and chronic obstructive pulmonary disease.
    American journal of respiratory medicine : drugs, devices, and other interventions, 2002, Volume: 1, Issue:2

    Topics: Adenosine; Asthma; Bronchoconstriction; Humans; Inflammation; Mast Cells; Pulmonary Disease, Chronic Obstructive; Receptors, Purinergic P1

2002
Direct or indirect stimuli for bronchial challenge testing: what is the relevance for asthma epidemiology?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:1

    Topics: Adenosine; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Histamine; Humans; Methacholine Chloride; Predictive Value of Tests; Prevalence

2004
Adenosine, inflammation and asthma--a review.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53, Issue:5

    Topics: Adenosine; Animals; Asthma; Basophils; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Humans; Inflammation; Mast Cells; Receptors, Purinergic P1

2004
Indirect bronchial hyper-responsiveness: the coming of age of a specific group of bronchial challenges.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:3

    Topics: Adenosine; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Exercise Test; Humans; Mannitol; Osmosis; Sports

2005
[Indirect bronchial provocation tests: a new, specific group of bronchial provocation tests for asthma].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 2005, Volume: 67, Issue:3

    Topics: Adenosine; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Humans; Pulmonary Ventilation; Tachykinins

2005
Adenosine signaling in asthma and chronic obstructive pulmonary disease.
    Current opinion in pulmonary medicine, 2006, Volume: 12, Issue:1

    Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Humans; Lung; Mast Cells; Mice; Pulmonary Disease, Chronic Obstructive; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1

2006
Adenosine receptors: promising targets for the development of novel therapeutics and diagnostics for asthma.
    Fundamental & clinical pharmacology, 2006, Volume: 20, Issue:1

    Topics: Adenosine; Animals; Anti-Asthmatic Agents; Asthma; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Receptors, Purinergic P1

2006
Adenosine in the airways: implications and applications.
    European journal of pharmacology, 2006, Mar-08, Volume: 533, Issue:1-3

    Topics: Adenosine; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Diagnosis, Differential; Humans; Pulmonary Disease, Chronic Obstructive; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Respiratory System

2006
Adenosine signalling in airways.
    Current opinion in pharmacology, 2006, Volume: 6, Issue:3

    Topics: Adenosine; Adenosine Monophosphate; Animals; Asthma; Bronchial Provocation Tests; Diagnosis, Differential; Humans; Pulmonary Disease, Chronic Obstructive; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Adenosine A2; Respiratory System; Signal Transduction

2006
Role of adenosine receptors in the treatment of asthma and chronic obstructive pulmonary disease: recent developments.
    Drugs in R&D, 2007, Volume: 8, Issue:1

    Topics: Adenosine; Asthma; Bronchoconstriction; Humans; Models, Biological; Pulmonary Disease, Chronic Obstructive; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Technology, Pharmaceutical

2007
Adenosine receptor modulation: potential implications in veterinary medicine.
    Veterinary journal (London, England : 1997), 2009, Volume: 179, Issue:1

    Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Cat Diseases; Cats; Horse Diseases; Horses; Inflammation; Pulmonary Disease, Chronic Obstructive; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction

2009
Provocative challenges to help diagnose and monitor asthma: exercise, methacholine, adenosine, and mannitol.
    Current opinion in pulmonary medicine, 2008, Volume: 14, Issue:1

    Topics: Adenosine; Adolescent; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Child, Preschool; Exercise; Humans; Mannitol; Methacholine Chloride; Respiratory Function Tests

2008
Adenosine receptors and asthma.
    British journal of pharmacology, 2008, Volume: 153 Suppl 1

    Topics: Adenosine; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Humans; Inflammation; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1

2008
[Animal experiments and clinical studies on the role of adenosine in bronchial asthma].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1984, Volume: 46, Issue:6

    Topics: Adenosine; Adult; Animals; Asthma; Atropine; Basophils; Bronchi; Bronchodilator Agents; Cromolyn Sodium; Double-Blind Method; Female; Hexamethonium Compounds; Humans; Inosine; Lung; Male; Mast Cells; Random Allocation; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Urethane; Vagotomy; Xanthines

1984
Theophylline use in asthma. Some current issues.
    Clinics in chest medicine, 1984, Volume: 5, Issue:4

    Topics: Adenosine; Adrenergic beta-Agonists; Animals; Asthma; Bronchi; Cardiac Output; Cyclic AMP; Drug Therapy, Combination; Humans; Kinetics; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Purinergic; Stroke Volume; Theophylline

1984
The profile of action of enprofylline, or why adenosine antagonism seems less desirable with xanthine antiasthmatics.
    Agents and actions. Supplements, 1983, Volume: 13

    Topics: Adenosine; Animals; Asthma; Bronchi; Cats; Central Nervous System; Chemical Phenomena; Chemistry; Diuresis; Guinea Pigs; Heart; Humans; Lung; Mice; Nausea; Rats; Structure-Activity Relationship; Theophylline; Xanthines

1983
[Animal models of bronchial hyperreactivity].
    Revue des maladies respiratoires, 1994, Volume: 11, Issue:2

    Topics: Adenosine; Animals; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chronic Disease; Cytokines; Dextrans; Disease Models, Animal; Dogs; Guinea Pigs; Inflammation; Leukotrienes; Lipoxygenase; Mast Cells; Ozone; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Tachykinins

1994
Direct and indirect bronchial responsiveness.
    Respiratory medicine, 1993, Volume: 87 Suppl B

    Topics: Adenosine; Asthma; Bronchi; Bronchial Provocation Tests; Humans; Tachykinins

1993
Purine derivatives in the study of allergic inflammation in respiratory diseases.
    Allergy, 1997, Volume: 52, Issue:34 Suppl

    Topics: Adenosine; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Guinea Pigs; Humans; Inflammation; Purine Nucleosides; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal

1997
Adenosine bronchoprovocation: a promising marker of allergic inflammation in asthma?
    Thorax, 1997, Volume: 52, Issue:10

    Topics: Adenosine; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Humans

1997
Theophylline and airway inflammation.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1998, Volume: 28 Suppl 3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Administration, Oral; Anti-Inflammatory Agents; Asthma; Biopsy; Bronchi; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Eosinophils; Humans; Leukocyte Count; Lymphocyte Count; Theophylline

1998
Asthma, adenosine, mast cells and theophylline.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1998, Volume: 28 Suppl 3

    Topics: Adenosine; Animals; Anti-Inflammatory Agents; Asthma; Cytokines; Humans; Immunohistochemistry; Lung; Mast Cells; NF-kappa B; Theophylline

1998
Adenosine, mast cells and asthma.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1999, Volume: 48, Issue:6

    Topics: Adenosine; Animals; Asthma; Bronchi; Bronchoalveolar Lavage; Humans; In Vitro Techniques; Mast Cells; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists

1999
Experimental models in asthma.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29 Suppl 3

    Topics: Adenosine; Asthma; Asthma, Exercise-Induced; Bronchoconstriction; Cold Temperature; Histamine; Humans; Mast Cells

1999
Species differences in adenosine receptor-mediated bronchoconstrictor responses.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2000, Volume: 30, Issue:9

    Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Guinea Pigs; Humans; Rabbits; Rats; Receptors, Purinergic P1; Species Specificity

2000
Indirect bronchial hyperresponsiveness in asthma: mechanisms, pharmacology and implications for clinical research.
    The European respiratory journal, 2000, Volume: 16, Issue:3

    Topics: Adenosine; Adenosine Monophosphate; Adrenergic beta-Antagonists; Aerosols; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Exercise; Humans; Propranolol; Pulmonary Ventilation; Sulfites; Sulfur Dioxide; Tachykinins

2000
RASONs: a novel antisense oligonucleotide therapeutic approach for asthma.
    Expert opinion on biological therapy, 2001, Volume: 1, Issue:6

    Topics: Adenosine; Asthma; Gene Expression Regulation; Humans; Oligonucleotides, Antisense; Receptors, Purinergic P1

2001
Adenosine: a key effector molecule of asthma or just another mediator?
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:2

    Topics: Adenosine; Asthma; Humans; Lung

2002
Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease.
    Thorax, 2002, Volume: 57, Issue:7

    Topics: Adenosine; Adenosine Monophosphate; Asthma; Bronchi; Bronchoconstriction; Humans; Pulmonary Disease, Chronic Obstructive

2002
Processes and bronchial hyperresponsiveness.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1991, Volume: 21 Suppl 1

    Topics: Adenosine; Animals; Asthma; Bronchi; Humans; Inflammation; Neurokinin A; Neuropeptides; Rats

1991
Adenosine: a positive modulator of airway inflammation in asthma.
    Annals of the New York Academy of Sciences, 1991, Volume: 629

    Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Humans; Inflammation; Mast Cells; Respiratory Physiological Phenomena; Respiratory System

1991
Tryptase, a mediator of human mast cells.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 2

    Topics: Adenosine; Anaphylaxis; Asthma; Basophils; Blood Coagulation; Humans; Immunoassay; Mast Cells; Mastocytosis; Muscle Contraction; Muscle, Smooth; Peptide Hydrolases

1990
Adenosine bronchoconstriction in asthma: investigations into its possible mechanism of action.
    British journal of clinical pharmacology, 1990, Volume: 30 Suppl 1

    Topics: Adenosine; Animals; Asthma; Bronchoconstriction; Humans

1990
Adenosine and adenosine receptors.
    American journal of respiratory cell and molecular biology, 1990, Volume: 2, Issue:2

    Topics: Adenosine; Animals; Asthma; Humans; Lung; Receptors, Purinergic

1990
Adenosine in asthmatic lung.
    Progress in clinical and biological research, 1988, Volume: 263

    Topics: Adenosine; Asthma; Bronchial Spasm; Histamine Release; Humans

1988
Adenosine as a pro-inflammatory mediator in asthma.
    Pulmonary pharmacology, 1989, Volume: 2, Issue:1

    Topics: Adenosine; Animals; Asthma; Humans; Inflammation

1989
Purines and sensory neuropeptides in human asthma.
    Bulletin europeen de physiopathologie respiratoire, 1987, Volume: 23 Suppl 10

    Topics: Adenosine; Asthma; Humans; Neuropeptides; Receptors, Neurotransmitter; Receptors, Purinergic; Receptors, Tachykinin; Tachykinins

1987
Xanthines--symptomatic or prophylactic in asthma?
    Agents and actions. Supplements, 1988, Volume: 23

    Topics: Adenosine; Animals; Asthma; Bronchi; Humans; In Vitro Techniques; Inflammation; Muscle Contraction; T-Lymphocytes; Xanthines

1988
Effects of enprofylline and theophylline may show the role of adenosine.
    Life sciences, 1986, Mar-24, Volume: 38, Issue:12

    Topics: Adenosine; Animals; Asthma; Brain; Bronchodilator Agents; Caffeine; Diuresis; Fatty Acids, Nonesterified; Gastric Acid; Heart; Humans; Kidney; Kinetics; Lung; Natriuresis; Phosphodiesterase Inhibitors; Receptors, Cell Surface; Receptors, Purinergic; Respiration; Seizures; SRS-A; Theophylline; Vasoconstriction; Vasodilation; Xanthines

1986
Relationships between adenosine, cyclic nucleotides, and xanthines in asthma.
    The Journal of allergy and clinical immunology, 1986, Volume: 78, Issue:4 Pt 2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Asthma; Bronchi; Catecholamines; Humans; Xanthines

1986
Inflammatory mechanisms and nocturnal asthma.
    The American journal of medicine, 1988, Jul-29, Volume: 85, Issue:1B

    Topics: Adenosine; Asthma; Blood Platelets; Circadian Rhythm; Eosinophils; Epithelium; Histamine; Humans; Inflammation; Lymphocytes; Macrophages; Mast Cells; Neutrophils; Platelet Activating Factor; Prostaglandins; SRS-A

1988
Bronchial hyperresponsiveness is not bronchial hyperresponsiveness is not bronchial asthma.
    Clinical allergy, 1988, Volume: 18, Issue:4

    Topics: Acetylcholine; Adenosine; Airway Resistance; Animals; Asthma; Bronchi; Histamine; Humans; Methacholine Chloride; Methacholine Compounds; Neuropeptides

1988
Mechanisms and significance of adenosine-induced bronchoconstriction in asthma.
    Allergy, 1987, Volume: 42, Issue:7

    Topics: Adenosine; Adenosine Monophosphate; Airway Obstruction; Aminophylline; Asthma; Bronchi; Bronchodilator Agents; Xanthines

1987
The action of purines on human airways.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 280, Issue:2 Suppl

    Topics: Adenine Nucleotides; Adenosine; Asthma; Bronchi; Humans; Purine Nucleosides; Purine Nucleotides; Purines; Respiratory System

1986
Development of safer xanthine drugs for treatment of obstructive airways disease.
    The Journal of allergy and clinical immunology, 1986, Volume: 78, Issue:4 Pt 2

    Topics: Adenosine; Animals; Asthma; Brain; Cardiovascular System; Humans; Lung; Lung Diseases, Obstructive; Structure-Activity Relationship; Xanthines

1986
Mast cell mediators in the blood of patients with asthma.
    Chest, 1985, Volume: 87, Issue:1 Suppl

    Topics: Adenosine; Antigens; Asthma; Bronchial Spasm; Chemotactic Factors; Histamine; Humans; Mast Cells; Platelet Activating Factor; Urticaria

1985

Trials

22 trial(s) available for adenosine and Asthma

ArticleYear
Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-induced responses in patients with mild asthma: a double-blind, randomised, parallel-group study.
    Respiratory research, 2019, Dec-19, Volume: 20, Issue:1

    Topics: Adenosine; Administration, Intranasal; Adolescent; Adult; Allergens; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Double-Blind Method; Female; Humans; Male; Middle Aged; Phenylacetates; Toll-Like Receptor 7; Treatment Outcome; Young Adult

2019
Bronchial Provocation Testing Can Be Improved by Using Dry Powder Adenosine Instead of Nebulized Adenosine Monophosphate.
    American journal of respiratory and critical care medicine, 2018, 02-01, Volume: 197, Issue:3

    Topics: Adenosine; Adenosine Monophosphate; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dry Powder Inhalers; Female; Forced Expiratory Volume; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis

2018
Effect of ticagrelor on pulmonary function in healthy elderly volunteers and asthma or chronic obstructive pulmonary disease patients.
    Current medical research and opinion, 2013, Volume: 29, Issue:5

    Topics: Adenosine; Aged; Asthma; Double-Blind Method; Female; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Purinergic P2Y Receptor Antagonists; Respiratory Rate; Respiratory Transport; Ticagrelor

2013
Effects of ciclesonide and fluticasone on cortisol secretion in patients with persistent asthma.
    The European respiratory journal, 2009, Volume: 33, Issue:6

    Topics: Adenosine; Adolescent; Adult; Aged; Albuterol; Analysis of Variance; Androstadienes; Anti-Allergic Agents; Area Under Curve; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Female; Fluticasone; Forced Expiratory Volume; Humans; Hydrocortisone; Least-Squares Analysis; Male; Methacholine Chloride; Middle Aged; Placebos; Pregnenediones; Salmeterol Xinafoate; Spirometry; Treatment Outcome

2009
Pharmacological stress myocardial perfusion scintigraphy: use of a modified adenosine protocol in patients with asthma.
    Nuclear medicine communications, 2009, Volume: 30, Issue:3

    Topics: Adenosine; Aged; Albuterol; Asthma; Bronchial Spasm; Case-Control Studies; Female; Humans; Male; Myocardial Perfusion Imaging; Premedication; Safety; Stress, Physiological; Time Factors

2009
Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:6

    Topics: Adenosine; Adenosine Monophosphate; Adolescent; Asthma; Biomarkers; Breath Tests; Child; Child, Preschool; Cross-Sectional Studies; Cystic Fibrosis; Humans; Mass Spectrometry; Predictive Value of Tests; Respiratory Function Tests; Signal Transduction; Urea; Young Adult

2009
Safety of binodenoson, a selective adenosine A2A receptor agonist vasodilator pharmacological stress agent, in healthy subjects with mild intermittent asthma.
    Circulation. Cardiovascular imaging, 2009, Volume: 2, Issue:6

    Topics: Adenosine; Adolescent; Adult; Analysis of Variance; Asthma; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Female; Humans; Male; Middle Aged; Placebos; Respiratory Function Tests; Single-Blind Method; Treatment Outcome; Vasodilator Agents

2009
Is methacholine challenge sufficient to rule out bronchial hyperresponsiveness in patients with suspected asthma?
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2012, Volume: 108, Issue:2

    Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Diagnosis, Differential; Female; Humans; Male; Methacholine Chloride; Middle Aged; Predictive Value of Tests; Prognosis; Sensitivity and Specificity

2012
The effect of montelukast on bronchial provocation tests and exhaled nitric oxide levels in asthmatic patients.
    The Israel Medical Association journal : IMAJ, 2003, Volume: 5, Issue:11

    Topics: Acetates; Adenosine; Administration, Oral; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child; Cyclopropanes; Exercise; Female; Humans; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Quinolines; Spirometry; Sulfides; Treatment Outcome; Vasodilator Agents

2003
The pulmonary effects of intravenous adenosine in asthmatic subjects.
    Respiratory research, 2006, Nov-30, Volume: 7

    Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Dose-Response Relationship, Drug; Dyspnea; Female; Humans; Injections, Intravenous; Lung; Male; Respiratory Mechanics

2006
The effect of ABT-761, a novel 5-lipoxygenase inhibitor, on exercise- and adenosine-induced bronchoconstriction in asthmatic subjects.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Adenosine; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Exercise; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Male; Middle Aged; Vasodilator Agents

1997
Protective effects of inhaled ipratropium bromide on bronchoconstriction induced by adenosine and methacholine in asthma.
    The European respiratory journal, 1992, Volume: 5, Issue:5

    Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchoconstriction; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Ipratropium; Male; Methacholine Chloride; Middle Aged; Reflex; Vagus Nerve

1992
Adenosine-induced bronchoconstriction in human asthmatics: effects of pretreatment with indomethacin or atropine sulfate.
    Pulmonary pharmacology, 1990, Volume: 3, Issue:1

    Topics: Adenosine; Administration, Inhalation; Administration, Oral; Adult; Asthma; Atropine; Bronchial Provocation Tests; Bronchoconstrictor Agents; Double-Blind Method; Humans; Indomethacin; Male; Methacholine Chloride

1990
Repeated exposure of asthmatic airways to inhaled adenosine 5'-monophosphate attenuates bronchoconstriction provoked by exercise.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:3 Pt 1

    Topics: Adenosine; Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchoconstriction; Female; Forced Expiratory Volume; Histamine; Humans; Male

1990
Tachyphylaxis to repeated challenges with inhaled adenosine in asthmatic subjects.
    Annals of allergy, 1990, Volume: 65, Issue:2

    Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Tachyphylaxis

1990
Effect of sodium cromoglycate and nifedipine on adenosine-induced bronchoconstriction.
    Respiration; international review of thoracic diseases, 1988, Volume: 53, Issue:2

    Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Calcium; Cromolyn Sodium; Double-Blind Method; Female; Humans; Ion Channels; Male; Nifedipine; Random Allocation

1988
Comparative study of the effects of nedocromil sodium (4 mg) and sodium cromoglycate (10 mg) on adenosine-induced bronchoconstriction in asthmatic subjects.
    Clinical allergy, 1988, Volume: 18, Issue:4

    Topics: Adenosine; Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Nedocromil; Quinolines; Random Allocation

1988
Adenosine-induced bronchoconstriction: comparison between nedocromil sodium and sodium cromoglycate.
    European journal of respiratory diseases. Supplement, 1986, Volume: 147

    Topics: Adenosine; Adolescent; Adult; Asthma; Cromolyn Sodium; Female; Forced Expiratory Volume; Humans; Male; Nedocromil; Quinolines; Skin Tests

1986
Influence of infused adenosine on bronchial tone and bronchial reactivity in asthma.
    Chest, 1988, Volume: 93, Issue:2

    Topics: Adenosine; Adult; Asthma; Blood Pressure; Bronchi; Bronchial Provocation Tests; Female; Heart Rate; Humans; Infusions, Intravenous; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Muscle, Smooth; Respiratory Function Tests

1988
Enhancing effect of dipyridamole inhalation on adenosine-induced bronchospasm in asthmatic patients.
    Allergy, 1988, Volume: 43, Issue:3

    Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Asthma; Bronchi; Bronchial Spasm; Dipyridamole; Drug Synergism; Female; Humans; Male; Middle Aged

1988
The combined effects of two pairs of mediators, adenosine with methacholine and prostaglandin D2 with histamine, on airway calibre in asthma.
    Clinical science (London, England : 1979), 1986, Volume: 71, Issue:4

    Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchi; Dose-Response Relationship, Drug; Drug Synergism; Female; Histamine; Humans; Male; Methacholine Chloride; Methacholine Compounds; Prostaglandins D; Time Factors

1986
Specific antagonism of adenosine-induced bronchoconstriction in asthma by oral theophylline.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:5

    Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchi; Bronchodilator Agents; Female; Forced Expiratory Volume; Histamine; Humans; Male; Random Allocation; Theophylline

1985

Other Studies

104 other study(ies) available for adenosine and Asthma

ArticleYear
m6A regulator-mediated RNA methylation modification patterns and immune microenvironment infiltration characterization in severe asthma.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:21

    Topics: Adenosine; Animals; Asthma; Biomarkers; Cellular Microenvironment; Computational Biology; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Methylation; Mice; Models, Biological; RNA, Messenger; ROC Curve; Severity of Illness Index; Transcriptome

2021
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adenosine; Allergens; Animals; Asthma; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Epigenome; Female; Gene Expression Profiling; Humans; Hypersensitivity; Immunity; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Signal Transduction

2021
m6A echoes with DNA methylation: Coordinated DNA methylation and gene expression data analysis identified critical m6A genes associated with asthma.
    Gene, 2022, Jun-20, Volume: 828

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Asthma; CCAAT-Enhancer-Binding Proteins; Data Analysis; DNA Methylation; Gene Expression; Humans; Mixed Function Oxygenases; Proto-Oncogene Proteins; RNA-Binding Proteins; Ubiquitin-Protein Ligases

2022
Endogenous Adenosine 5'-Monophosphate, But Not Acetylcholine or Histamine, is Associated with Asthma Control, Quality of Life, and Exacerbations.
    Lung, 2022, Volume: 200, Issue:5

    Topics: Acetylcholine; Adenosine; Adenosine Monophosphate; Asthma; Biomarkers; Chemokine CCL22; Histamine; Humans; Interleukin-13; Interleukin-17; Interleukin-4; Interleukin-5; Interleukin-6; Interleukin-8; Quality Control; Quality of Life; Sputum; Tumor Necrosis Factor-alpha

2022
Abnormal adenosine metabolism of neutrophils inhibits airway inflammation and remodeling in asthma model induced by Aspergillus fumigatus.
    BMC pulmonary medicine, 2023, Jul-14, Volume: 23, Issue:1

    Topics: Adenosine; Airway Remodeling; Animals; Aspergillus fumigatus; Asthma; Bronchoalveolar Lavage Fluid; Chemokines; Cytokines; Inflammation; Mice; Neutrophils; Plant Extracts

2023
Incidence of acute bronchospasm during systemic adenosine administration for coronary angiography.
    The journal of the Royal College of Physicians of Edinburgh, 2019, Volume: 49, Issue:3

    Topics: Adenosine; Aged; Asthma; Bronchial Spasm; Coronary Angiography; Humans; Incidence; Infusions, Intravenous; Middle Aged; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Vasodilator Agents

2019
DZNep attenuates allergic airway inflammation in an ovalbumin-induced murine model.
    Molecular immunology, 2021, Volume: 131

    Topics: Adenosine; Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Hypersensitivity; Inflammation; Lung; Mice; Mice, Inbred BALB C; Ovalbumin

2021
RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis.
    Developmental cell, 2021, 04-19, Volume: 56, Issue:8

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Asthma; Cilia; Ciliopathies; Demethylation; Embryo, Mammalian; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Mice, Inbred C57BL; Mice, Knockout; Organogenesis; Phenotype; Respiratory Mucosa; RNA Stability; RNA, Messenger; Xenopus laevis

2021
Can bronchial challenge test with adenosine or methacholine at preschool age predict school-age asthma?
    Pediatric pulmonology, 2021, Volume: 56, Issue:10

    Topics: Adenosine; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Child; Child, Preschool; Female; Humans; Infant; Male; Methacholine Chloride; Schools

2021
ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing.
    The European respiratory journal, 2018, Volume: 52, Issue:5

    Topics: Adenosine; Advisory Committees; Asthma; Bronchial Provocation Tests; Europe; Humans; Mannitol; Methacholine Chloride; Respiratory Hypersensitivity; Societies, Medical

2018
Associations of AMP and adenosine induced dyspnea sensation to large and small airways dysfunction in asthma.
    BMC pulmonary medicine, 2019, Jan-28, Volume: 19, Issue:1

    Topics: Adenosine; Adenosine Monophosphate; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dyspnea; Female; Forced Expiratory Volume; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Spirometry

2019
Asthmatic Augmentation of Airway Vagal Activity Involves Decreased Central Expression and Activity of CD73 in Rats.
    ACS chemical neuroscience, 2019, 06-19, Volume: 10, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Asthma; Excitatory Postsynaptic Potentials; Male; Neurons; Rats; Rats, Sprague-Dawley; Vagus Nerve

2019
The absence of mrp4 has no effect on the recruitment of neutrophils and eosinophils into the lung after LPS, cigarette smoke or allergen challenge.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adenosine; Allergens; Animals; Asthma; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bronchoalveolar Lavage Fluid; Cyclic AMP; Cytokines; Diketopiperazines; Eosinophils; Heterocyclic Compounds, 4 or More Rings; Lipopolysaccharides; Lung; Mice; Multidrug Resistance-Associated Proteins; Neutrophils; Ovalbumin; Phosphodiesterase 4 Inhibitors; Propionates; Pulmonary Disease, Chronic Obstructive; Quinolines; Rolipram; Smoking; Th2 Cells; Time Factors

2013
Adenosine signaling in airways: toward a promising antiasthmatic approach.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: Adenosine; Animals; Anti-Asthmatic Agents; Asthma; Humans; Respiratory System; Signal Transduction

2013
Rapid and severe adverse reaction to adenosine during a pharmacological stress test for a myocardial perfusion scan.
    Clinical nuclear medicine, 2013, Volume: 38, Issue:9

    Topics: Adenosine; Albuterol; Asthma; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Myocardial Perfusion Imaging

2013
Adenosine dry powder inhalation for bronchial challenge testing, part 2: proof of concept in asthmatic subjects.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2014, Volume: 88, Issue:1

    Topics: Adenosine; Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dry Powder Inhalers; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Pilot Projects; Powders

2014
Down-regulation of the A3 adenosine receptor in human mast cells upregulates mediators of angiogenesis and remodeling.
    Molecular immunology, 2015, Volume: 65, Issue:1

    Topics: Adenosine; Adenosine A3 Receptor Antagonists; Amphiregulin; Anti-Inflammatory Agents; Asthma; Cell Line, Tumor; Dexamethasone; Down-Regulation; EGF Family of Proteins; Humans; Interleukin-6; Interleukin-8; Jurkat Cells; Lung; Mast Cells; Neovascularization, Pathologic; Osteopontin; Phosphorylation; Receptor, Adenosine A3; RNA Interference; RNA, Small Interfering; Up-Regulation; Vascular Endothelial Growth Factor A

2015
Pollen-derived adenosine is a necessary cofactor for ragweed allergy.
    Allergy, 2015, Volume: 70, Issue:8

    Topics: Adenosine; Administration, Intranasal; Animals; Antigens, Plant; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Epithelial Cells; Female; Humans; Immunization; Lung; Mice; Mice, Inbred BALB C; Plant Extracts; Random Allocation; Respiratory Hypersensitivity; Risk Assessment; Sensitivity and Specificity; Th2 Cells

2015
Adenosine influences myeloid cells to inhibit aeroallergen sensitization.
    American journal of physiology. Lung cellular and molecular physiology, 2016, 05-15, Volume: 310, Issue:10

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Asthma; Cell Polarity; Cells, Cultured; Drug Evaluation, Preclinical; Immunologic Factors; Lipopolysaccharides; Male; Mice, Inbred C57BL; Myeloid Cells; Receptor, Adenosine A2A; T-Lymphocytes

2016
[Advances in the study of A2B adenosine receptor antagonists].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Asthmatic Agents; Asthma; Humans; Pulmonary Artery; Structure-Activity Relationship; Xanthines

2008
A2A adenosine receptor agonists for the treatment of asthma?
    Allergy, 2008, Volume: 63, Issue:8

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Asthma; Humans; Receptor, Adenosine A2A; Treatment Outcome

2008
Finding better therapeutic targets for patients with asthma: adenosine receptors?
    British journal of pharmacology, 2008, Volume: 155, Issue:4

    Topics: Adenosine; Anti-Asthmatic Agents; Asthma; Drug Delivery Systems; Drug Design; Humans; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists

2008
A2A adenosine receptor deficiency leads to impaired tracheal relaxation via NADPH oxidase pathway in allergic mice.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 330, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Asthma; Disease Models, Animal; Female; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; NADPH Oxidases; Phenethylamines; Reactive Oxygen Species; Receptor, Adenosine A2A; Signal Transduction; Trachea

2009
Airway hyperresponsiveness, peak flow variability and inflammatory markers in non-asthmatic subjects with respiratory infections.
    The clinical respiratory journal, 2007, Volume: 1, Issue:1

    Topics: Adenosine; Adult; Aged; Air; Asthma; Biomarkers; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cold Temperature; Common Cold; Eosinophil Cationic Protein; Humans; Inflammation; Methacholine Chloride; Middle Aged; Nitric Oxide; Peak Expiratory Flow Rate; Respiratory Sounds; Young Adult

2007
Conversion of Th17-type into Th2-type inflammation by acetyl salicylic acid via the adenosine and uric acid pathway in the lung.
    Allergy, 2010, Volume: 65, Issue:9

    Topics: Adenosine; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Lung; Mice; Mice, Inbred C57BL; Th17 Cells; Th2 Cells; Uric Acid

2010
Involvement of A1 adenosine receptors in altered vascular responses and inflammation in an allergic mouse model of asthma.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Administration, Inhalation; Aerosols; Ambrosia; Animals; Antigens, Plant; Aorta; Asthma; Blotting, Western; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Plethysmography, Whole Body; Polymerase Chain Reaction; Receptor, Adenosine A1; RNA, Messenger; Vasodilation

2010
Disparity in FcεRI-induced degranulation of primary human lung and skin mast cells exposed to adenosine.
    Journal of clinical immunology, 2011, Volume: 31, Issue:3

    Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Asthma; Bronchoconstriction; Bronchoconstrictor Agents; Cell Degranulation; Gene Expression; Humans; Lung; Mast Cells; Organ Specificity; Receptor, Adenosine A3; Receptors, IgE; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin

2011
Comparison of bronchial hyperresponsiveness to methacholine and adenosine and airway inflammation markers in patients with suspected asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2011, Volume: 48, Issue:4

    Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Biomarkers; Breath Tests; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Eosinophils; Exhalation; Female; Humans; Inflammation; Leukocyte Count; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Sensitivity and Specificity; Sputum; Young Adult

2011
Pharmacological characterization of adenosine receptors on isolated human bronchi.
    American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:6

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Asthma; Bronchi; Bronchoconstriction; Capsaicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organ Culture Techniques; Receptor, Adenosine A1; Sensory System Agents; Vasodilator Agents

2011
Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma.
    The European respiratory journal, 2002, Volume: 20, Issue:6

    Topics: Adenosine; Adult; Asthma; Breath Tests; Case-Control Studies; Female; Humans; Male; Reproducibility of Results; Respiratory Function Tests; Saliva

2002
Characterization of adenosine receptor(s) involved in adenosine-induced bronchoconstriction in an allergic mouse model.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:6

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic Agonists; Adrenergic Antagonists; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Hypersensitivity; Lung; Male; Mice; Mice, Inbred BALB C; Phenethylamines; Pyridines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasodilator Agents

2003
A patient with chaotic atrial tachycardia.
    Pediatric emergency care, 2003, Volume: 19, Issue:2

    Topics: Abnormalities, Multiple; Adenosine; Anti-Asthmatic Agents; Asthma; Bronchiolitis; Combined Modality Therapy; Diagnosis, Differential; Dyspnea; Electroencephalography; Emergencies; Female; Fluid Therapy; Furosemide; Heart Failure; Heart Septal Defects, Atrial; Humans; Infant; Procainamide; Recurrence; Tachycardia; Tachycardia, Ectopic Atrial

2003
IL-13 and adenosine: partners in a molecular dance?
    The Journal of clinical investigation, 2003, Volume: 112, Issue:3

    Topics: Adenosine; Animals; Asthma; Humans; Inflammation; Interleukin-13; Lung Injury; Mice; Models, Biological; Signal Transduction; T-Lymphocytes

2003
Adenosine levels in the exhaled breath condensate: a potential surrogate marker of airway inflammation.
    The European respiratory journal, 2003, Volume: 22, Issue:2

    Topics: Adenosine; Asthma; Biomarkers; Breath Tests; Humans

2003
Selectively enhanced sensitivity of bronchoalveolar lavage fluid (BALF) mast cells to IgE dependent stimulation in mild asthmatics.
    Asian Pacific journal of allergy and immunology, 2003, Volume: 21, Issue:2

    Topics: Adenosine; Adult; Antibodies, Anti-Idiotypic; Asthma; Bronchoalveolar Lavage Fluid; Bronchoscopes; Calcimycin; Colon; Dose-Response Relationship, Immunologic; Female; Forced Expiratory Volume; Histamine Release; Humans; Immunoglobulin E; Ionophores; Lung; Male; Mast Cells; Middle Aged; Sensitivity and Specificity; Severity of Illness Index; Vasodilator Agents

2003
Dust mite-induced asthma in cynomolgus monkeys.
    Journal of applied physiology (Bethesda, Md. : 1985), 2004, Volume: 96, Issue:4

    Topics: Adenosine; Aerosols; Allergens; Animals; Asthma; Bronchial Provocation Tests; Cytokines; Disease Models, Animal; Dust; Histamine; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immunization; Immunoglobulin E; Immunoglobulin G; Lung; Macaca fascicularis; Mites; Respiratory Function Tests; Respiratory Hypersensitivity; Respiratory System; Th2 Cells; Time Factors

2004
[Replacement of ACTH in certain cases by adenosine triphosphoric acid].
    La Presse medicale, 1952, Apr-26, Volume: 60, Issue:29

    Topics: Adenosine; Adenosine Triphosphate; Adrenocorticotropic Hormone; Asthma; Gout; Polyphosphates; Replantation; Rheumatic Diseases

1952
[Effect of adenosine and anti-IgE antibody on histamine release from mast cells in BALF of asthma patients].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2003, Volume: 19, Issue:5

    Topics: Adenosine; Adult; Antibodies, Anti-Idiotypic; Asthma; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Female; Histamine Release; Humans; Male; Mast Cells; Middle Aged

2003
Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: an A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma.
    Journal of immunology (Baltimore, Md. : 1950), 2004, Jun-15, Volume: 172, Issue:12

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Asthma; B-Lymphocytes; Cell Communication; Cells, Cultured; Coculture Techniques; Cytokines; Humans; Immunoglobulin E; Interleukin-13; Interleukin-4; Mast Cells; Receptor, Adenosine A2B; RNA, Messenger; Th2 Cells; Up-Regulation

2004
Adenosine up-regulation of the mucin gene, MUC2, in asthma.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:14

    Topics: Adenosine; Asthma; ErbB Receptors; Humans; Ion Channels; Mucin-2; Mucins; Niflumic Acid; Phosphorylation; Receptors, Purinergic P1; Respiratory Mucosa; Trachea; Transcriptional Activation; Up-Regulation

2004
Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. 1983.
    British journal of clinical pharmacology, 2004, Volume: 58, Issue:7

    Topics: Adenosine; Administration, Inhalation; Airway Resistance; Asthma; Case-Control Studies; Guanosine; History, 20th Century; Humans

2004
A1 antagonism in asthma: better than coffee?
    The Journal of clinical investigation, 2005, Volume: 115, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Asthma; Coffee; Humans; Lung; Lung Injury; Receptor, Adenosine A1; Signal Transduction

2005
Mast cell degranulation after endobronchial adenosine challenge.
    The Journal of allergy and clinical immunology, 2005, Volume: 115, Issue:5

    Topics: Adenosine; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Humans; Mast Cells

2005
The Quintiles Prize Lecture 2004. The identification of the adenosine A2B receptor as a novel therapeutic target in asthma.
    British journal of pharmacology, 2005, Volume: 145, Issue:8

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Humans; Mast Cells

2005
A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Dust; Histamine; Mites; Phosphodiesterase Inhibitors; Purines; Rabbits; Radioligand Assay; Receptor, Adenosine A1

2005
Role of adenosine in airway inflammation in an allergic mouse model of asthma.
    International immunopharmacology, 2006, Volume: 6, Issue:1

    Topics: Adenosine; Animals; Asthma; beta-N-Acetylhexosaminidases; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chemokines, CC; Disease Models, Animal; Eosinophil Peroxidase; Immunization; Inflammation; Inflammation Mediators; Male; Mast Cells; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Pollen; Respiratory System

2006
Mast cell numbers in airway smooth muscle and PC20AMP in asthma and COPD.
    Respiratory medicine, 2007, Volume: 101, Issue:5

    Topics: Adenosine; Adolescent; Adult; Aged; Asthma; Biopsy; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoscopy; Cell Count; Female; Forced Expiratory Volume; Humans; Male; Mast Cells; Middle Aged; Muscle, Smooth; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Tryptases

2007
Methotrexate regulates the expression of glucocorticoid receptor alpha and beta isoforms in normal human peripheral mononuclear cells and human lymphocyte cell lines in vitro.
    Molecular immunology, 2007, Volume: 44, Issue:8

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Asthma; Autoimmune Diseases; Drug Synergism; Gene Expression Regulation; Humans; Immunosuppressive Agents; Inflammation; Jurkat Cells; Lipopolysaccharides; Lymphocytes; Methotrexate; Protein Isoforms; Receptors, Glucocorticoid; Theobromine; Vasodilator Agents

2007
Effect of a specific and selective A(2B) adenosine receptor antagonist on adenosine agonist AMP and allergen-induced airway responsiveness and cellular influx in a mouse model of asthma.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Administration, Inhalation; Aerosols; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Plethysmography; Purines; Pyrazoles

2007
Adenosine receptors: novel targets for drug development in allergic rhinitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Volume: 37, Issue:1

    Topics: Adenosine; Adenosine A3 Receptor Antagonists; Asthma; Chronic Disease; Humans; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Rhinitis; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Signal Transduction

2007
Adenosine for salbutamol-induced supraventricular tachycardia.
    Intensive care medicine, 2007, Volume: 33, Issue:9

    Topics: Adenosine; Albuterol; Anti-Arrhythmia Agents; Asthma; Bronchodilator Agents; Humans; Male; Tachycardia, Supraventricular

2007
The safety and tolerability of adenosine in patients with obstructive airways disease.
    International journal of cardiology, 2008, Aug-29, Volume: 128, Issue:3

    Topics: Adenosine; Aged; Aged, 80 and over; Asthma; Cohort Studies; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Spirometry

2008
In vivo adenosine A(2B) receptor desensitization in guinea-pig airway smooth muscle: implications for asthma.
    European journal of pharmacology, 2007, Dec-01, Volume: 575, Issue:1-3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Asthma; Base Sequence; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Hypersensitivity; Isoproterenol; Muscle, Smooth; Purines; Receptor, Adenosine A2B; Reverse Transcriptase Polymerase Chain Reaction

2007
Elevated expression of adenosine A1 receptor in bronchial biopsy specimens from asthmatic subjects.
    The European respiratory journal, 2008, Volume: 31, Issue:2

    Topics: Adenosine; Administration, Inhalation; Asthma; Biomarkers; Biopsy, Needle; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Immunohistochemistry; Male; Prognosis; Receptor, Adenosine A1; Reference Values; Respiratory Function Tests; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Up-Regulation

2008
Mast cell activation after adenosine inhalation challenge in patients with bronchial asthma.
    Allergy, 2008, Volume: 63, Issue:1

    Topics: Adenosine; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Case-Control Studies; Dinoprost; Female; Humans; Inflammation Mediators; Male; Mast Cells; Reference Values; Sensitivity and Specificity

2008
Adenosine-mediated alteration of vascular reactivity and inflammation in a murine model of asthma.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:5

    Topics: Acetylcholine; Adenosine; Administration, Inhalation; Allergens; Ambrosia; Animals; Aorta; Asthma; Disease Models, Animal; Dose-Response Relationship, Drug; Flavins; Inflammation; Inflammation Mediators; Lung; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Plant Proteins; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Vasodilation; Vasodilator Agents; Xanthines

2008
Adenosine-induced respiratory arrest in an asthmatic patient.
    Southern medical journal, 2008, Volume: 101, Issue:3

    Topics: Adenosine; Aged; Asthma; Exercise Test; Female; Humans; Respiratory Insufficiency; Vasodilator Agents

2008
Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells.
    The Journal of allergy and clinical immunology, 2008, Volume: 122, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Asthma; Bronchial Hyperreactivity; Female; Hexosaminidases; Lung; Mast Cells; Mice; Mice, Inbred C57BL; Receptor, Adenosine A3

2008
Universal adenosine receptor antagonism is neither necessary nor desirable with xanthine antiasthmatics.
    Medical hypotheses, 1982, Volume: 8, Issue:5

    Topics: Adenosine; Airway Resistance; Animals; Asthma; Central Nervous System; Diuresis; Dose-Response Relationship, Drug; Humans; Mice; Natriuresis; Neural Inhibition; Phosphodiesterase Inhibitors; Rats; Receptors, Cell Surface; Receptors, Purinergic; Seizures; Theophylline

1982
Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects.
    British journal of clinical pharmacology, 1983, Volume: 15, Issue:2

    Topics: Adenosine; Adolescent; Adult; Aged; Airway Resistance; Asthma; Bronchi; Constriction, Pathologic; Cyclic AMP; Forced Expiratory Volume; Guanosine; Humans; Middle Aged; Respiratory Therapy; Sodium Chloride; Theophylline

1983
Adenosine as a bronchoconstrictor mediator in asthma and its antagonism by methylxanthines.
    The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:3 Pt 1

    Topics: Adenosine; Asthma; Bronchi; Humans; Immunoglobulin E; Mast Cells; Theophylline; Xanthines

1984
Adenosine antagonism as an alternative mechanism of action of methylxanthines in asthma.
    Agents and actions. Supplements, 1983, Volume: 13

    Topics: Adenosine; Adenosine Monophosphate; Airway Resistance; Asthma; Bronchi; Dose-Response Relationship, Drug; Guanosine; Histamine; Humans; Inosine; Theophylline

1983
Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline.
    The American review of respiratory disease, 1984, Volume: 129, Issue:3

    Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Drug Antagonism; Female; Forced Expiratory Volume; Histamine; Humans; Male; Theophylline

1984
Adenosine antagonism, a less desirable characteristic of xanthine asthma drugs?
    Acta pharmacologica et toxicologica, 1981, Volume: 49, Issue:4

    Topics: Adenosine; Animals; Asthma; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Rats; Theophylline; Xanthines

1981
Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Anti-Asthmatic Agents; Asthma; Calcium; Cyclic AMP; Humans; Inositol Phosphates; Interleukin-8; Mast Cells; Receptors, Purinergic P1; Tumor Cells, Cultured; Xanthines

1995
Bronchospasm after intravenous administration of adenosine in a patient with asthma.
    The Journal of pediatrics, 1994, Volume: 125, Issue:5 Pt 1

    Topics: Adenosine; Adolescent; Asthma; Bronchial Spasm; Bronchodilator Agents; Female; Humans; Infusions, Intravenous; Tachycardia, Supraventricular

1994
Adenosine-induced bronchoconstriction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: evidence for an inducible adenosine A1 receptor.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Adenosine; Animals; Asthma; Binding, Competitive; Bronchoconstriction; Disease Models, Animal; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Purinergic P1; Trachea; Vaccination; Xanthines

1994
Bronchospasm induced by intravenous adenosine.
    Human & experimental toxicology, 1994, Volume: 13, Issue:4

    Topics: Adenosine; Aged; Asthma; Bronchial Spasm; Contraindications; Humans; Injections, Intravenous; Male; Middle Aged; Tachycardia, Supraventricular

1994
Adenosine-induced bronchoconstriction in conscious hyperresponsive and sensitized guinea pigs.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:2 Pt 1

    Topics: Adenosine; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol; Guinea Pigs; Immunization; Male; Ovalbumin; Ozone; Platelet Activating Factor

1994
Adenosine in bronchoalveolar lavage fluid in asthma.
    The American review of respiratory disease, 1993, Volume: 148, Issue:1

    Topics: Adenosine; Adult; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoscopy; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Middle Aged; Nebulizers and Vaporizers; Reference Values; Smoking; Spirometry

1993
Airway hyper- or hyporeactivity to inhaled spasmogens 24 h after ovalbumin challenge of sensitized guinea-pigs.
    British journal of pharmacology, 1995, Volume: 116, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Administration, Inhalation; Airway Resistance; Animals; Asthma; Atropine; Bronchial Spasm; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Methacholine Chloride; Ovalbumin; Plethysmography, Whole Body; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents

1995
Asthma. Blocking adenosine with antisense.
    Nature, 1997, Feb-20, Volume: 385, Issue:6618

    Topics: Adenosine; Animals; Asthma; Gene Expression; Humans; Lung; Oligonucleotides, Antisense; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1

1997
DNA antisense therapy for asthma in an animal model.
    Nature, 1997, Feb-20, Volume: 385, Issue:6618

    Topics: Adenosine; Administration, Inhalation; Animals; Antigens, Dermatophagoides; Asthma; Bronchial Hyperreactivity; Cross-Over Studies; Disease Models, Animal; DNA, Antisense; Glycoproteins; Humans; Lung; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Respiratory Function Tests

1997
[Anomalous reaction to adenosine of lymphocytes from patients with atopic bronchial asthma. Is it a link in pathogenesis or a compensatory reaction?].
    Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 122, Issue:10

    Topics: Adenosine; Asthma; CD4 Antigens; CD8 Antigens; Cytotoxicity, Immunologic; Humans; Lymphocyte Activation; T-Lymphocytes

1996
A1 adenosine receptor-mediated Ins(1,4,5)P3 generation in allergic rabbit airway smooth muscle.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Adenosine; Airway Resistance; Allergens; Animals; Asthma; Bronchi; Dust; Estrenes; Immunoglobulin E; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lung Compliance; Mites; Muscle Contraction; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Pyrrolidinones; Rabbits; Receptors, Purinergic P1; Respiratory Hypersensitivity

1998
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Using intravenous adenosine in asthmatics.
    Emergency medicine journal : EMJ, 2001, Volume: 18, Issue:1

    Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Contraindications; Emergencies; Evidence-Based Medicine; Female; Humans; Infusions, Intravenous; Risk Factors; Tachycardia, Supraventricular

2001
Role of adenosine in asthma.
    Drug development research, 1996, Volume: 39

    Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Bronchodilator Agents; Dogs; Humans; Lung; Mast Cells; Mice; Rats; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Theophylline; Xanthines

1996
Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Oct-15, Volume: 167, Issue:8

    Topics: Adenosine; Adenosine Deaminase; Animals; Asthma; Bronchi; Bronchitis; Cell Count; Chemokine CCL7; Cytokines; Digestive System; Eosinophils; Lung; Macrophages, Alveolar; Male; Mice; Mice, Mutant Strains; Monocyte Chemoattractant Proteins; Pneumonia; Receptors, Purinergic P1; Respiratory Mucosa; RNA, Messenger; Signal Transduction

2001
Gene expression profiling in inflammatory airway disease associated with elevated adenosine.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Animals; Asthma; Chemokine CCL7; Cytokines; Endothelial Growth Factors; Eosinophils; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Lung; Lymphokines; Mice; Mice, Transgenic; Monocyte Chemoattractant Proteins; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
[Image analysis of airway remodeling and responsiveness in asthmatic guinea pig].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2001, Volume: 24, Issue:2

    Topics: Acetylcholine; Adenosine; Aminophylline; Animals; Asthma; Guinea Pigs; Heparin; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Vasodilator Agents

2001
Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat.
    European journal of pharmacology, 2002, Mar-08, Volume: 438, Issue:3

    Topics: Adenosine; Allergens; Animals; Anti-Inflammatory Agents; Asthma; Blood Pressure; Budesonide; Dose-Response Relationship, Drug; Inflammation; Lung; Male; Ovalbumin; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred BN; Receptor, Adenosine A2A; Triazines; Triazoles; Vascular Resistance

2002
Adenosine-induced bronchoconstriction in an allergic rabbit model: antagonism by theophylline aerosol.
    Agents and actions, 1992, Volume: 37, Issue:3-4

    Topics: Adenosine; Aerosols; Anesthesia; Animals; Asthma; Bronchial Hyperreactivity; Histamine; Pollen; Rabbits; Respiratory Hypersensitivity; Theophylline

1992
Isolated bronchi from asthmatics are hyperresponsive to adenosine, which apparently acts indirectly by liberation of leukotrienes and histamine.
    The American review of respiratory disease, 1992, Volume: 145, Issue:5

    Topics: Adenosine; Asthma; Bronchi; Bronchial Hyperreactivity; Female; Histamine Release; Humans; In Vitro Techniques; Leukotrienes; Male; Middle Aged

1992
[Mechanisms of the joint action of cortisol and adenosine on peripheral blood lymphocytes in bronchial asthma].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 111, Issue:1

    Topics: Adenosine; Asthma; Cells, Cultured; Culture Media; Cyclic AMP; Humans; Hydrocortisone; In Vitro Techniques; Lymphocytes; Stimulation, Chemical

1991
Effects of NZ-107 on tracheal responses to adenosine in the guinea pig.
    Japanese journal of pharmacology, 1991, Volume: 56, Issue:1

    Topics: Adenosine; Aminophylline; Animals; Asthma; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Pyridazines; Trachea

1991
Bronchial challenge with adenosine causes the release of serum neutrophil chemotactic factor in asthma.
    The American review of respiratory disease, 1991, Volume: 143, Issue:5 Pt 1

    Topics: Adenosine; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Chemotaxis, Leukocyte; Female; Humans; Interleukin-8; Male; Middle Aged; Neutrophils; Theophylline

1991
[Studies of adenosine inhalation in asthmatic patients].
    Arerugi = [Allergy], 1990, Volume: 39, Issue:3

    Topics: Adenosine; Administration, Inhalation; Adult; Aged; Asthma; Bronchi; Cyclic AMP; Female; Humans; Leukotrienes; Male; Middle Aged; Thromboxane B2

1990
Role of purinergic system in tracheobronchial reactivity of healthy and bronchopathic subjects.
    International journal of tissue reactions, 1990, Volume: 12, Issue:1

    Topics: Adenosine; Adolescent; Adult; Aged; Albuterol; Aminophylline; Asthma; Bronchi; Bronchitis; Bronchodilator Agents; Child; Drug Combinations; Female; Forced Expiratory Volume; Humans; Male; Metaproterenol; Middle Aged; Receptors, Purinergic; Theophylline; Trachea

1990
Superoxide generation and its modulation by adenosine in the neutrophils of subjects with asthma.
    The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:5

    Topics: Adenosine; Administration, Inhalation; Adolescent; Adult; Asthma; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides

1989
Asthmatic patients have neutrophils that exhibit diminished responsiveness to adenosine.
    The American review of respiratory disease, 1989, Volume: 140, Issue:6

    Topics: 2-Chloroadenosine; Adenosine; Asthma; Calcimycin; Cytochalasin B; Dinoprostone; Dose-Response Relationship, Drug; Humans; Isoproterenol; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides

1989
Adenosine revisited.
    Lancet (London, England), 1985, Oct-26, Volume: 2, Issue:8461

    Topics: Adenosine; Arrhythmias, Cardiac; Asthma; Coronary Circulation; Humans; Kidney

1985
Adenosine-induced bronchoconstriction in asthma: role of mast cell-mediator release.
    The Journal of allergy and clinical immunology, 1985, Volume: 75, Issue:2

    Topics: Adenosine; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chemotactic Factors; Cromolyn Sodium; Cyclic AMP; Female; Forced Expiratory Volume; Histamine; Humans; Interleukin-8; Male; Mast Cells; Middle Aged

1985
On the mechanism of action of theophylline and caffeine.
    Acta medica Scandinavica, 1985, Volume: 217, Issue:2

    Topics: Adenosine; Asthma; Caffeine; Calcium; Cyclic AMP; Humans; Muscle Contraction; Receptors, Cell Surface; Receptors, Purinergic; Theophylline

1985
Adenosine-induced bronchoconstriction in asthma. Role of parasympathetic stimulation and adrenergic inhibition.
    The American review of respiratory disease, 1985, Volume: 132, Issue:1

    Topics: Adenosine; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Constriction, Pathologic; Female; Histamine; Histamine Antagonists; Humans; Ipratropium; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Receptors, Adrenergic, beta; Respiratory Function Tests; Vagus Nerve

1985
The bronchial effects of adenosine in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 280, Issue:2 Suppl

    Topics: Adenosine; Anesthesia; Animals; Asthma; Bronchi; Dose-Response Relationship, Drug; Hexamethonium Compounds; Injections, Intravenous; Pressure; Rats; Receptors, Cell Surface; Receptors, Purinergic; Xanthines

1986
Adenosine-induced bronchoconstriction: premedication with chlorpheniramine and nedocromil sodium.
    European journal of respiratory diseases. Supplement, 1986, Volume: 147

    Topics: Adenosine; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Chlorpheniramine; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Nedocromil; Quinolines

1986
Effect of nedocromil sodium on adenosine- and methacholine-induced bronchospasm in asthma.
    Clinical allergy, 1987, Volume: 17, Issue:2

    Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Nedocromil; Quinolines

1987
[Capnography-controlled adenosine loading in chronic respiratory tract diseases in childhood].
    Orvosi hetilap, 1988, Apr-17, Volume: 129, Issue:16

    Topics: Adenosine; Aerosols; Asthma; Carbon Dioxide; Child; Chronic Disease; Female; Humans; Immunoglobulin E; Lung Diseases, Obstructive; Male; Respiratory Function Tests; Rhinitis, Allergic, Perennial

1988
[The role of vagal reflex on adenosine-induced bronchoconstriction in asthma].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1988, Volume: 11, Issue:5

    Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Female; Humans; Male; Reflex; Vagus Nerve

1988
Effect of adenosine and pertussis vaccine on lymphocyte response in vitro to phytohemagglutinin in asthmatic and non-asthmatic subjects.
    Annals of allergy, 1988, Volume: 61, Issue:2

    Topics: Adenosine; Adult; Asthma; Dose-Response Relationship, Immunologic; Humans; Immune Tolerance; Lymphocyte Activation; Pertussis Vaccine; Phytohemagglutinins

1988
Contribution of inflammatory mediators to the immediate asthmatic reaction.
    The American review of respiratory disease, 1987, Volume: 135, Issue:6 Pt 2

    Topics: Adenosine; Allergens; Asthma; Bronchi; Bronchial Spasm; Humans; Mast Cells; Prostaglandin D2; Prostaglandins D; Skin

1987
Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:5

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Asthma; Bronchi; Bronchial Provocation Tests; Forced Expiratory Volume; Histamine; Humans; Inosine; Kinetics; Methacholine Chloride; Methacholine Compounds

1986
Mediators and asthma.
    British journal of hospital medicine, 1985, Volume: 34, Issue:6

    Topics: Adenosine; Asthma; Bradykinin; Bronchial Spasm; Chemotactic Factors; Chemotaxis, Leukocyte; Histamine; Humans; Lipoxygenase; Nerve Tissue Proteins; Platelet Activating Factor; Prostaglandins; SRS-A

1985
The effect of dipyridamole on histamine- and adenosine-induced bronchoconstriction in normal and asthmatic subjects.
    European journal of respiratory diseases, 1985, Volume: 67, Issue:3

    Topics: Adenosine; Administration, Intranasal; Adult; Asthma; Bronchi; Dipyridamole; Female; Histamine; Humans; Infusions, Parenteral; Male; Middle Aged

1985