Page last updated: 2024-08-24

adenosine and Acute Myelogenous Leukemia

adenosine has been researched along with Acute Myelogenous Leukemia in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199022 (40.74)18.7374
1990's1 (1.85)18.2507
2000's1 (1.85)29.6817
2010's12 (22.22)24.3611
2020's18 (33.33)2.80

Authors

AuthorsStudies
Du, A; Gao, Y; Jiang, B; Wang, J; Wu, X; Zhang, P; Zhao, Q1
Feng, Y; Gu, J; He, Y; Huang, K; Kang, B; Li, X; Li, Y; Liu, J; Long, B; Mai, Y; Pan, G; Shan, Y; Sun, Y; Wang, T; Wen, R; Zhang, C; Zhang, T; Zhang, W; Zhang, X; Zhu, Y1
Chen, Y; Deng, J; Li, H; Lou, S; Shen, Y; Zhang, N; Zhang, P1
Chen, R; Issah, MA; Lai, G; Liu, Y; Shen, J; Wu, D; Zhang, F; Zheng, W1
Fu, Y; Huang, L; Huang, M; Liu, H; Shen, D; You, Y; Zhao, B; Zheng, Y1
Dou, L; Fang, S; Jiao, Y; Wang, H; Wang, L; Wang, N; Wei, Y; Wen, Y; Yang, J1
Gong, Y; Ouyang, X1
Cui, S; Gao, C; Liu, P; Liu, Z; Ma, C; Tan, X; Xu, R1
Chen, J; Chen, Y; Chen, Z; Gao, X; Hong, YG; Liu, T; Liu, W; Wen, R; Wu, GC; Xia, J; Yang, Z; Zhao, Y; Zheng, Y; Zhou, C1
An, O; Cao, X; Chan, E; Chan, THM; Chen, L; Chng, WJ; Chun, CM; Fullwood, MJ; Goh, Y; Guo, M; Iwanaga, E; Jen, WY; Koh, BTH; Koh, LP; Li, Y; Matsuoka, M; Ng, VHE; Ooi, MGM; Osato, M; Peramangalam, PS; Pulikkan, JA; Song, Y; Tan, LK; Tan, ZH; Tan, ZQ; Tenen, DG; Wang, W; Yang, H; Zhou, Q1
Chlubek, D; Dziedziejko, V; Kłos, P; Puchałowicz, K; Tarnowski, M; Tkacz, M1
Gong, Y; Huang, J; Li, Y; Naren, D; Sang, L; Yan, T; Zhang, D; Zheng, X1
Aspris, D; Tzelepis, K; Yankova, E1
Chai, J; Chang, J; Chen, J; Cheng, Y; Cui, M; Feng, M; Gao, K; Gao, Z; Guo, C; Han, G; Hu, J; Li, S; Li, Y; Liu, L; Liu, W; Wang, J; Wang, P; Wang, Q; Xie, X; Yin, R; Zhang, H; Zhang, T; Zhou, F1
Albertella, M; Andrews, B; Aspris, D; Bannister, AJ; Blackaby, W; De Braekeleer, E; Dias, JML; Eleftheriou, M; Fosbeary, R; Gozdecka, M; Guest, P; Hendrick, AG; Irigoyen, N; Jeremias, I; Kouzarides, T; Leggate, D; Pilka, ES; Rak, J; Rausch, O; Tsagkogeorga, G; Tzelepis, K; Vassiliou, GS; Vick, B; Webster, NA; Yankova, E1
Barin, E; Cheng, Y; Chu, KL; Jaffrey, SR; Kharas, MG; Luo, H; Mo, S; Nguyen, DT; Patel, DJ; Pickering, BF; Rohwetter, TM; Savino, AM; Velleca, A; Xie, W; Yang, X1
Chen, J; Qing, Y; Su, R1
Bhaduri-McIntosh, S; Cui, XL; Gu, X; He, C; Huang, Y; Li, L; Li, W; Liu, Y; Qian, Z; Shen, B; Sheng, Y; Wei, J; Wu, Q; Xu, H; Yu, C; Yu, F1
Averink, TV; Brumatti, G; Ekert, PG; Holik, AZ; Infusini, G; Sandow, JJ; Webb, AI1
Aspris, D; Bannister, AJ; Barbieri, I; De Braekeleer, E; Han, N; Hendrick, A; Kouzarides, T; Migliori, V; Millán-Zambrano, G; Pandolfini, L; Ponstingl, H; Robson, SC; Shi, J; Tzelepis, K; Vakoc, CR; Vassiliou, GS1
Martin, GH; Park, CY1
He, JR; Wang, XS; Yu, J; Yu, S1
Fatica, A; Ianniello, Z1
Christopher, MJ; Klco, JM; Ley, TJ; Sarkaria, SM1
Armstrong, SA; Banka, D; Bernt, KM; Bradner, JE; Chang, J; Chen, CW; Chen, L; Cihan, A; Deshpande, A; Deshpande, AJ; Dias, S; Dzhekieva, L; Fazio, M; Ibáñez, G; Koche, R; Krivtsov, A; Luo, M; Roeder, RG; Sinha, AU; Zhu, N1
Anjos-Afonso, F; Bonnet, D; Currie, E; Griessinger, E; Horswell, S; Luis Sardina, J; Niavarani, A; Reyal, Y1
Chai, CL; Chng, WJ; Guan, P; Jiang, X; Lee, PL; Li, J; Li, Z; Lim, CZ; Pan, J; Yatim, SM; Yu, Q; Zhou, J1
Andreazza, AC; Bralha, FN; Chingcuanco, FB; Fung, TA; Hurren, R; Laposa, RR; Liyanage, SU; Psarianos, P; Salmena, L; Schimmer, AD; Son, MH; Tung, AY; Wang, X1
Andreeff, M; Campbell, CT; Chevassut, T; Daigle, SR; Deng, L; Goodell, MA; Jeong, M; Kornblau, SM; Li, W; Luo, M; Rau, RE; Rodriguez, BA; Rogers, JH; Rosen, A; Song, Y; Sweet, S1
Atadja, P; Balusu, R; Bhalla, KN; Buckley, KM; Chen, J; Fernandez, P; Fiskus, W; Jillella, A; Koul, S; Marquez, VE; Rao, R; Shi, H; Sreekumar, A; Ustun, C; Wang, Y1
Bi, C; Cheong, LL; Chng, WJ; Koh, TL; Liu, SC; Mahara, S; Tay, KG; Yu, Q; Zhou, J1
Golde, DW; Koeffler, HP1
Dexter, DL; Ghoda, LY; Parks, RE; Savarese, TM1
Grever, MR; Heldman, DA; Trewyn, RW1
Attadia, V; Cacciapuoti, G; Cartenì-Farina, M; Di Fiore, PP; Grieco, M; Pinto, A; Porcelli, M1
Cadossi, R; Torelli, G; Torelli, U1
Chheda, GB; Cox, C; Dutta, SP; Tritsch, GL1
Hattori, M; Honma, Y; Hozumi, M; Ishikawa, I; Kanaiwa, T; Kawahara, N; Makishima, M; Motoyoshi, K; Ogura, H; Sampi, K1
Kane, MA; Raptis, G; Roth, E; Schreiber, C; Waxman, S1
Davies, LC; Harrap, KR; Orr, RM; Powles, RL; Stock, JA; Taylor, GA1
Cannistra, AJ; Montgomery, JA; Parks, RE; Savarese, TM; Secrist, JA; Shortnacy, AT1
Chiang, PK; Glazer, RI; Hartman, KD; Knode, MC; Marquez, VE; Richard, MM; Tseng, CK1
Aarbakke, J; Bessesen, A; Chiang, PK; Gordon, RK; Miura, GA; Prytz, PS; Slørdal, L1
Chiang, PK; Gordon, RK; Miura, GA; Montgomery, JA1
Ferro, AJ; Fitchen, JH; Olson, KD; Riscoe, MK; Schwamborn, J1
Li, SY; Stoeckler, JD1
Chen, SF; Cleaveland, JS; Hollmann, AB; Parks, RE; Stoeckler, JD; Wiemann, MC1
Boucheix, C; Henry, J; Kahn, A; Perrot, JY; Phan-Dinh-Tuy, F; Rosenfeld, C1
Cohen, MB; Glazer, RI; Hartman, KD; Knode, MC; Linevsky, J1
Caen, J; Janneau, C; Lukasiewicz, H; Vainer, H1
Bloom, GE1
Torelli, G; Torelli, U1
Caen, J; Jeanneau, C; Popesco, E; Sultan, Y1
Nishino, T1

Reviews

5 review(s) available for adenosine and Acute Myelogenous Leukemia

ArticleYear
Recent Advances of m6A Demethylases Inhibitors and Their Biological Functions in Human Diseases.
    International journal of molecular sciences, 2022, May-22, Volume: 23, Issue:10

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; RNA; RNA, Messenger

2022
One Stone, Two Birds: N6-Methyladenosine RNA Modification in Leukemia Stem Cells and the Tumor Immune Microenvironment in Acute Myeloid Leukemia.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenosine; Humans; Leukemia, Myeloid, Acute; Methylation; RNA; Stem Cells; Tumor Microenvironment

2022
The N6-methyladenosine RNA modification in acute myeloid leukemia.
    Current opinion in hematology, 2021, 03-01, Volume: 28, Issue:2

    Topics: Adenosine; Animals; Biomarkers; Disease Management; Disease Susceptibility; Epigenesis, Genetic; Epigenomics; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Methylation; RNA

2021
RNA modifications in hematopoietic malignancies: a new research frontier.
    Blood, 2021, 08-26, Volume: 138, Issue:8

    Topics: Adenosine; Hematologic Neoplasms; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Methylation; RNA Processing, Post-Transcriptional; RNA, Neoplasm

2021
N6-Methyladenosine Role in Acute Myeloid Leukaemia.
    International journal of molecular sciences, 2018, Aug-09, Volume: 19, Issue:8

    Topics: Adenosine; DNA; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Methylation; RNA Processing, Post-Transcriptional; RNA, Messenger

2018

Other Studies

49 other study(ies) available for adenosine and Acute Myelogenous Leukemia

ArticleYear
m6A Regulator-Mediated Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Acute Myeloid Leukemia.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adenosine; B7-H1 Antigen; Biomarkers, Tumor; Case-Control Studies; Databases, Genetic; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Methylation; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mutation; Programmed Cell Death 1 Ligand 2 Protein; RNA Processing, Post-Transcriptional; RNA, Neoplasm; Signal Transduction; Tumor Microenvironment

2021
Vitamin C promotes anti-leukemia of DZNep in acute myeloid leukemia.
    Biochimica et biophysica acta. Molecular basis of disease, 2022, 05-01, Volume: 1868, Issue:5

    Topics: Adenosine; Ascorbic Acid; Enhancer of Zeste Homolog 2 Protein; Histone Methyltransferases; Humans; Leukemia, Myeloid, Acute

2022
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability.
    Experimental & molecular medicine, 2022, Volume: 54, Issue:2

    Topics: Adenosine; Apoptosis; Chromosomal Proteins, Non-Histone; Guanine Nucleotide Exchange Factors; Humans; Leukemia, Myeloid, Acute; RNA; RNA-Binding Proteins; RNA, Messenger

2022
Expression profiling of N
    Biochemical and biophysical research communications, 2022, 04-23, Volume: 601

    Topics: Adenosine; Adult; Gene Expression Profiling; Gene Regulatory Networks; Humans; Leukemia, Myeloid, Acute; MicroRNAs; RNA, Circular

2022
[Characteristics of N6-methyladenosine modification patterns in t(8;21) acute myeloid leukemia].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2022, May-20, Volume: 42, Issue:5

    Topics: Adenosine; Humans; Leukemia, Myeloid, Acute; RNA, Messenger; Transcriptome

2022
The Identification of APOBEC3G as a Potential Prognostic Biomarker in Acute Myeloid Leukemia and a Possible Drug Target for Crotonoside.
    Molecules (Basel, Switzerland), 2022, Sep-07, Volume: 27, Issue:18

    Topics: Adenosine; APOBEC-1 Deaminase; APOBEC-3G Deaminase; Biological Products; Biomarkers; Cytidine Deaminase; Cytosine; Guanosine; HIV-1; Humans; Leukemia, Myeloid, Acute; Molecular Docking Simulation; Prognosis; RNA; Uracil

2022
The RNA m6A Reader YTHDF1 Is Required for Acute Myeloid Leukemia Progression.
    Cancer research, 2023, 03-15, Volume: 83, Issue:6

    Topics: Adenosine; Animals; Cyclins; Humans; Leukemia, Myeloid, Acute; Mice; RNA; RNA-Binding Proteins; RNA, Messenger

2023
Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.
    Blood, 2023, Jun-22, Volume: 141, Issue:25

    Topics: Adenosine; Adenosine Deaminase; Core Binding Factor Alpha 2 Subunit; Core Binding Factors; Down-Regulation; Humans; Leukemia, Myeloid, Acute; RNA Editing

2023
Extracellular Adenine Nucleotides and Adenosine Modulate the Growth and Survival of THP-1 Leukemia Cells.
    International journal of molecular sciences, 2020, Jun-22, Volume: 21, Issue:12

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Affinity Labels; Apoptosis; Cell Cycle; Cell Movement; Cell Proliferation; Extracellular Matrix; Humans; Leukemia, Myeloid, Acute; Thionucleotides; Tumor Cells, Cultured

2020
High Wilms' tumor 1 associating protein expression predicts poor prognosis in acute myeloid leukemia and regulates m
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:1

    Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Apoptosis; Biomarkers, Tumor; Case-Control Studies; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; DNA Methylation; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Proto-Oncogene Proteins c-myc; RNA Splicing Factors; RNA, Messenger; Survival Rate; Tumor Cells, Cultured; Young Adult

2021
YBX1 is required for maintaining myeloid leukemia cell survival by regulating BCL2 stability in an m6A-dependent manner.
    Blood, 2021, 07-08, Volume: 138, Issue:1

    Topics: Adenosine; Animals; Apoptosis; Cell Survival; Gene Deletion; Gene Expression Regulation, Leukemic; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Mice, Inbred C57BL; Protein Stability; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins; RNA, Neoplasm; Y-Box-Binding Protein 1

2021
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
    Nature, 2021, Volume: 593, Issue:7860

    Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Line, Tumor; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Methyltransferases; Mice; Mice, Inbred C57BL; Molecular Structure; Xenograft Model Antitumor Assays

2021
N
    Cancer cell, 2021, 07-12, Volume: 39, Issue:7

    Topics: Adenosine; Animals; Apoptosis; Cell Differentiation; Cell Nucleus; Cell Proliferation; DNA Methylation; Female; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Liquid-Liquid Extraction; Mice; Mice, Inbred NOD; Mice, SCID; Nerve Tissue Proteins; Phase Transition; Proto-Oncogene Proteins c-myc; RNA Splicing Factors; RNA Stability; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2021
A critical role of nuclear m6A reader YTHDC1 in leukemogenesis by regulating MCM complex-mediated DNA replication.
    Blood, 2021, 12-30, Volume: 138, Issue:26

    Topics: Adenosine; Animals; Carcinogenesis; Cell Line, Tumor; DNA Replication; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Mice, Transgenic; Minichromosome Maintenance Complex Component 4; Minichromosome Maintenance Proteins; Nerve Tissue Proteins; RNA Splicing Factors; Up-Regulation

2021
Quantitative proteomic analysis of EZH2 inhibition in acute myeloid leukemia reveals the targets and pathways that precede the induction of cell death.
    Proteomics. Clinical applications, 2017, Volume: 11, Issue:9-10

    Topics: Adenosine; Animals; Carcinogenesis; Cell Death; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Leukemia, Myeloid, Acute; Mice; Molecular Targeted Therapy; Proteomics

2017
Promoter-bound METTL3 maintains myeloid leukaemia by m
    Nature, 2017, 12-07, Volume: 552, Issue:7683

    Topics: Adenosine; Animals; Cell Line, Tumor; Cell Proliferation; Chromatin; CRISPR-Cas Systems; Female; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Leukemia, Myeloid, Acute; Methyltransferases; Mice; Promoter Regions, Genetic; Protein Biosynthesis; Ribosomes; RNA, Messenger; Transcription Initiation Site

2017
Meddling with METTLs in Normal and Leukemia Stem Cells.
    Cell stem cell, 2018, 02-01, Volume: 22, Issue:2

    Topics: Adenosine; Cell Differentiation; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Methyltransferases; RNA, Messenger

2018
[Methyltransferase-like 3 Promotes the Proliferation of Acute Myeloid Leukemia Cells by Regulating N6-methyladenosine Levels of MYC].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2018, Jun-28, Volume: 40, Issue:3

    Topics: Adenosine; Cell Proliferation; Humans; Leukemia, Myeloid, Acute; Methyltransferases; Proto-Oncogene Proteins c-myc

2018
Primary acute myeloid leukemia cells with IDH1 or IDH2 mutations respond to a DOT1L inhibitor in vitro.
    Leukemia, 2014, Volume: 28, Issue:12

    Topics: Adenosine; Cell Proliferation; Histone-Lysine N-Methyltransferase; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Methyltransferases; Mutation; Phenylurea Compounds

2014
AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
    Cancer cell, 2014, Dec-08, Volume: 26, Issue:6

    Topics: Adenosine; Animals; Bone Marrow Cells; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Mice; Mice, Transgenic; Molecular Sequence Data; Neoplasms, Experimental; Nuclear Pore Complex Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Phenylurea Compounds; Transcription Factors

2014
APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Adenosine; Base Sequence; Cytidine Deaminase; Guanine; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Molecular Sequence Data; Mutation; Proteins; RNA Editing; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sequence Analysis, DNA; Umbilical Cord; Wilms Tumor; WT1 Proteins

2015
Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML).
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adenosine; Animals; Drug Delivery Systems; Epigenesis, Genetic; Female; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Xenograft Model Antitumor Assays

2015
Targeting mitochondrial RNA polymerase in acute myeloid leukemia.
    Oncotarget, 2015, Nov-10, Volume: 6, Issue:35

    Topics: Adenosine; Animals; Antineoplastic Agents; Cell Death; Cell Proliferation; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Electron Transport Complex I; Electron Transport Complex IV; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid, Acute; Male; Mice, SCID; Mitochondria; Molecular Targeted Therapy; Oxidative Phosphorylation; RNA Interference; Signal Transduction; Time Factors; Transfection; Tumor Burden; U937 Cells; Xenograft Model Antitumor Assays

2015
DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
    Blood, 2016, 08-18, Volume: 128, Issue:7

    Topics: Adenosine; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Methyltransferases; Mice, Inbred C57BL; Molecular Targeted Therapy; Mutation; Phenylurea Compounds; Rats; Time Factors; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2016
Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.
    Blood, 2009, Sep-24, Volume: 114, Issue:13

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carrier Proteins; Cell Cycle; DNA-Binding Proteins; Drug Evaluation, Preclinical; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; HL-60 Cells; Humans; Hydroxamic Acids; Indoles; Leukemia, Myeloid, Acute; Neoplasm Proteins; Nuclear Proteins; Panobinostat; Polycomb Repressive Complex 2; Transcription Factors; Treatment Outcome; Tumor Cells, Cultured

2009
The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML.
    Blood, 2011, Sep-08, Volume: 118, Issue:10

    Topics: Adenosine; Animals; Apoptosis; Biomarkers, Tumor; Blotting, Western; Carrier Proteins; Cell Proliferation; Chromatin Immunoprecipitation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Epigenomics; Female; Gene Expression Profiling; Gene Silencing; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Oligonucleotide Array Sequence Analysis; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Reactive Oxygen Species; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Transcription Factors; Tumor Cells, Cultured

2011
Humoral modulation of human acute myelogenous leukemia cell growth in vitro.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: Adenosine; Cell Division; Cell Line; Colony-Stimulating Factors; Cyclic AMP; Hormones; Humans; Leukemia, Myeloid, Acute; Prostaglandins

1980
Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Adenosine; Cells, Cultured; Deoxyadenosines; Humans; Inosine; Leukemia; Leukemia, Myeloid, Acute; Methionine; Methylthioinosine; Purine-Nucleoside Phosphorylase; T-Lymphocytes; Thionucleosides

1983
Differential excretion of modified nucleosides in adult acute leukemia.
    Blood, 1983, Volume: 61, Issue:2

    Topics: Adenosine; Adult; Aged; Creatinine; Female; Guanosine; Humans; Inosine; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Nucleosides

1983
Inhibition of dimethyl sulfoxide-induced differentiation of Friend erythroleukemic cells by 5'-methylthioadenosine.
    Cancer research, 1984, Volume: 44, Issue:9

    Topics: Adenosine; Animals; Cell Differentiation; Cell Line; Clone Cells; Deoxyadenosines; Dimethyl Sulfoxide; Globins; Heme; Humans; Kinetics; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; RNA, Messenger; Thionucleosides

1984
Double stranded ribonucleic acid in human leukemic blast cells.
    European journal of cancer, 1975, Volume: 11, Issue:2

    Topics: Adenosine; Base Sequence; Cell Nucleus; Chromatography; Deoxyribonucleases; DNA; Humans; In Vitro Techniques; Leukemia; Leukemia, Myeloid, Acute; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Poly A-U; Ribonuclease T1; Ribonucleases; RNA; RNA, Ribosomal; Time Factors; Uridine

1975
Synthesis and biological activities of some N6-(nitro- and -aminobenzyl)adenosines.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:8

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Benzyl Compounds; Benzylamines; Cattle; Cell Division; Cells, Cultured; Humans; Intestinal Mucosa; Leukemia L1210; Leukemia, Myeloid, Acute; Mice; Nitro Compounds

1975
Induction of differentiation of human myeloid leukemia HL-60 cells by novel pyrimidine nucleoside analogs.
    Biochimica et biophysica acta, 1991, Aug-13, Volume: 1094, Issue:1

    Topics: Adenosine; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line; Granulocytes; Humans; Leukemia, Myeloid, Acute; Nitroblue Tetrazolium; Oxidation-Reduction; Pyrimidine Nucleosides; Ribonucleosides; Tumor Cells, Cultured

1991
Effect of intracellular folate concentration on the modulation of 5-fluorouracil cytotoxicity by the elevation of phosphoribosylpyrophosphate in cultured human KB cells.
    Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1

    Topics: Adenosine; Carcinoma, Squamous Cell; Cell Survival; Fluorouracil; Folic Acid; Glucose; Humans; KB Cells; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Nasopharyngeal Neoplasms; Pentosephosphates; Phosphoribosyl Pyrophosphate; Thymidine

1987
Inhibition of human leukaemic thymidylate kinase and L1210 ribonucleotide reductase by dinucleotides of adenosine and thymidine and their phosphonate analogues.
    Biochemical pharmacology, 1988, Feb-15, Volume: 37, Issue:4

    Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Humans; Kinetics; Leukemia L1210; Leukemia, Myeloid, Acute; Nucleoside-Phosphate Kinase; Oligonucleotides; Organophosphonates; Phosphotransferases; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thymidine

1988
5'-deoxy-5'-methylthioadenosine phosphorylase--IV. Biological activity of 2-fluoroadenine-substituted 5'-deoxy-5'-methylthioadenosine analogs.
    Biochemical pharmacology, 1987, Jun-15, Volume: 36, Issue:12

    Topics: Adenine Phosphoribosyltransferase; Adenosine; Cell Line; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Deoxyadenosines; Humans; Leukemia, Myeloid, Acute; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship; Thionucleosides

1987
3-Deazaneplanocin: a new and potent inhibitor of S-adenosylhomocysteine hydrolase and its effects on human promyelocytic leukemia cell line HL-60.
    Biochemical and biophysical research communications, 1986, Mar-13, Volume: 135, Issue:2

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Humans; Hydrolases; Leukemia, Myeloid, Acute; Liver

1986
Induction of HL-60 cell differentiation by 3-deaza-(+/-)-aristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase.
    Cancer research, 1986, Volume: 46, Issue:11

    Topics: Adenosine; Adenosylhomocysteinase; Cell Cycle; Cell Differentiation; Cell Line; Cell Survival; Humans; Hydrolases; Leukemia, Myeloid, Acute; S-Adenosylhomocysteine; S-Adenosylmethionine

1986
4'-Thioadenosine as a novel inhibitor of S-adenosylhomocysteine hydrolase and an inducer for the differentiation of HL-60 human leukemia cells.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Adenosine; Adenosylhomocysteinase; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Homocysteine; Humans; Hydrolases; Leukemia, Myeloid, Acute; Purine Nucleotides; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides

1986
Inhibition of growth but not differentiation of normal and leukemic myeloid cells by methylthioadenosine.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Adenosine; Cell Differentiation; Cell Division; Cell Line; Colony-Forming Units Assay; Deoxyadenosines; Granulocytes; Humans; Leukemia, Myeloid, Acute; Macrophages; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Thionucleosides

1987
Influx of 5'-deoxy-5'-methylthioadenosine into HL-60 human leukemia cells and erythrocytes.
    The Journal of biological chemistry, 1987, Jul-15, Volume: 262, Issue:20

    Topics: Adenosine; Biological Transport; Cell Line; Deoxyadenosines; Erythrocytes; Humans; Kinetics; Leukemia, Myeloid, Acute; Thionucleosides; Vasodilator Agents

1987
Changes in nucleoside transport of HL-60 human promyelocytic cells during N,N-dimethylformamide induced differentiation.
    Cancer research, 1986, Volume: 46, Issue:7

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Cell Differentiation; Cell Line; Coformycin; Deoxyadenosines; Dimethylformamide; Humans; Leukemia, Myeloid, Acute; Nucleosides; Pentostatin; Purines; Thioinosine

1986
Protein kinases in human leukemic cells.
    American journal of hematology, 1985, Volume: 19, Issue:3

    Topics: Adenosine; Azides; Carrier Proteins; Casein Kinases; Chromatography, DEAE-Cellulose; Cyclic AMP Receptor Protein; Granulocytes; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Phosphorylation; Protein Kinases; Receptors, Cyclic AMP

1985
Effect of neplanocin A on differentiation, nucleic acid methylation, and c-myc mRNA expression in human promyelocytic leukemia cells.
    Molecular pharmacology, 1985, Volume: 28, Issue:1

    Topics: Adenosine; Antimetabolites, Antineoplastic; Cell Differentiation; Cell Division; Cell Line; DNA, Neoplasm; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Methylation; Oncogenes; RNA, Neoplasm

1985
Biosynthetic activities in normal and pathological platelet populations.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53

    Topics: Adenosine; Adenosine Diphosphate; Blood Platelet Disorders; Blood Platelets; Blood Proteins; Cell Survival; Centrifugation, Density Gradient; Epinephrine; Glutamates; Glycogen; Glycogen Synthase; Histocompatibility Antigens; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lysine; Platelet Adhesiveness; Prostaglandins; Purpura, Thrombocytopenic; Thrombin; Thrombocytopenia

1972
Leukocyte adenosine deaminase phenotypes in acute leukemia.
    Cancer, 1972, Volume: 29, Issue:5

    Topics: Acute Disease; Adenosine; Aminohydrolases; Electrophoresis; Humans; Isoenzymes; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocytes; Muramidase; Mycosis Fungoides; Phenotype

1972
Poly (A)-containing molecules in heterogeneous nuclear RNA of normal PHA-stimulated lymphocytes and acute leukaemia blast cells.
    Nature: New biology, 1973, Aug-01, Volume: 244, Issue:135

    Topics: Adenine Nucleotides; Adenosine; Electrophoresis, Polyacrylamide Gel; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Micropore Filters; Polynucleotides; RNA; RNA, Neoplasm; Tritium; Uridine

1973
Acquired haemorrhagic diathesis in sideroblastic anemia (megakaryocytopathy and thrombocytopathy).
    Acta medica Scandinavica. Supplementum, 1971, Volume: 525

    Topics: Adenosine; Anemia, Sideroblastic; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Carbon Isotopes; Hemorrhagic Disorders; Humans; Leukemia, Myeloid, Acute; Megakaryocytes; Microscopy, Electron

1971
[Studies on platelet adhesiveness. II. On various diseases].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1970, Volume: 33, Issue:5

    Topics: Adenosine; Arteriosclerosis; Dextrans; Diabetes Mellitus; Dipyridamole; Female; Fibrinolytic Agents; Humans; Hyperlipidemias; Leukemia, Myeloid, Acute; Male; Platelet Adhesiveness

1970