Compounds > adenosine-5--(n-ethylcarboxamide)

adenosine-5--(n-ethylcarboxamide) and Hodgkin-Disease

adenosine-5--(n-ethylcarboxamide) has been researched along with Hodgkin-Disease* in 1 studies

Other Studies

1 other study(ies) available for adenosine-5--(n-ethylcarboxamide) and Hodgkin-Disease

Article	Year
3H-NECA binding to polymorphonuclear membrane: effect of sera from patients with Hodgkin's disease. Cancer investigation, 1994, Volume: 12, Issue:2 Several studies have shown that sera from patients with Hodgkin's disease contain factors capable of inhibiting polymorphonuclear functions, among them chemotaxis. In the present study, we investigated whether these sera, which were able to inhibit PMN chemotaxis in the agarose test, were also able to affect the 3H-NECA binding to PMN membrane obtained from healthy donors. Control experiments were carried out using PMN incubated with a pool of sera from healthy volunteers. No significant difference was found in the maximum number of binding sites; on the contrary, the equilibrium dissociation constant was significantly increased in the membrane preparation of PMN incubated with pathological serum. Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Aged; Cell Membrane; Chemotaxis, Leukocyte; Female; Hodgkin Disease; Humans; Immune Sera; Male; Middle Aged; Neutrophils	1994

Article

Year

3H-NECA binding to polymorphonuclear membrane: effect of sera from patients with Hodgkin's disease.

Cancer investigation, 1994, Volume: 12, Issue:2

Several studies have shown that sera from patients with Hodgkin's disease contain factors capable of inhibiting polymorphonuclear functions, among them chemotaxis. In the present study, we investigated whether these sera, which were able to inhibit PMN chemotaxis in the agarose test, were also able to affect the 3H-NECA binding to PMN membrane obtained from healthy donors. Control experiments were carried out using PMN incubated with a pool of sera from healthy volunteers. No significant difference was found in the maximum number of binding sites; on the contrary, the equilibrium dissociation constant was significantly increased in the membrane preparation of PMN incubated with pathological serum.

Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Aged; Cell Membrane; Chemotaxis, Leukocyte; Female; Hodgkin Disease; Humans; Immune Sera; Male; Middle Aged; Neutrophils

1994