adenine has been researched along with Ureteral Obstruction in 12 studies
Ureteral Obstruction: Blockage in any part of the URETER causing obstruction of urine flow from the kidney to the URINARY BLADDER. The obstruction may be congenital, acquired, unilateral, bilateral, complete, partial, acute, or chronic. Depending on the degree and duration of the obstruction, clinical features vary greatly such as HYDRONEPHROSIS and obstructive nephropathy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated antifibrotic effects of capsaicin in two mouse renal fibrosis models as follows: C57BL/6J mice were subjected to unilateral ureteral obstruction (UUO) and fed with an adenine-rich diet." | 8.12 | Capsaicin ameliorates renal fibrosis by inhibiting TGF-β1-Smad2/3 signaling. ( Li, X; Liu, Z; Meng, D; Tang, S; Wang, H; Wang, W; Wu, Y; Xia, W; Zhang, J; Zhou, X, 2022) |
| "Renal fibrosis is a common pathological feature of the progression of chronic kidney disease." | 5.46 | Valproic acid attenuates renal fibrosis through the induction of autophagy. ( Doi, S; Doi, T; Kawaoka, K; Masaki, T; Nakashima, A; Ueno, T; Yamada, K, 2017) |
| "We investigated antifibrotic effects of capsaicin in two mouse renal fibrosis models as follows: C57BL/6J mice were subjected to unilateral ureteral obstruction (UUO) and fed with an adenine-rich diet." | 4.12 | Capsaicin ameliorates renal fibrosis by inhibiting TGF-β1-Smad2/3 signaling. ( Li, X; Liu, Z; Meng, D; Tang, S; Wang, H; Wang, W; Wu, Y; Xia, W; Zhang, J; Zhou, X, 2022) |
| " We also investigated its efficacy in unilateral ureteral obstruction (UUO)-treated mice and in adenine-induced CKD rats." | 4.12 | Mucin-fused myeloid-derived growth factor (MYDGF164) exhibits a prolonged serum half-life and alleviates fibrosis in chronic kidney disease. ( Du, P; Wang, H; Wang, T; Yang, M; Yin, H, 2022) |
| " The efficacy of the CTGF vaccine on renal fibrosis was evaluated in adenine-induced CKD and unilateral ureteral obstruction (UUO) murine models." | 4.12 | Vaccination against connective tissue growth factor attenuates the development of renal fibrosis. ( Azegami, T; Hayashi, K; Hishikawa, A; Itoh, H; Nakamichi, R; Nakayama, T; Sugita, E; Yoshimoto, N, 2022) |
| " Mouse fibrotic kidney samples were collected from male C57BL/6J mice treated with an adenine-rich diet for 14 days or were subjected to 7 days of unilateral ureteral obstruction (UUO)." | 4.02 | Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys. ( Beyer, S; Boor, P; Djudjaj, S; Eckes, T; Gauer, S; Koch, A; Patyna, S; Pfeilschifter, J; Schaefer, L; Schwalm, S; Thomas, D; Trautmann, S, 2021) |
| " We used two animal models of renal fibrosis generated by a unilateral ureteral obstruction (UUO) and an adenine diet (AD) to investigate whether SAMiRNA-AREG inhibited renal fibrosis." | 4.02 | In vivo silencing of amphiregulin by a novel effective Self-Assembled-Micelle inhibitory RNA ameliorates renal fibrosis via inhibition of EGFR signals. ( Hwang, S; Kim, TR; Ko, Y; Lee, EY; Lee, JH; Park, HO; Park, JH; Son, B; Son, SS; Yun, SI, 2021) |
| "Renal fibrosis is an inevitable outcome of various manifestations of progressive chronic kidney diseases (CKD)." | 1.72 | The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice. ( Alolga, RN; Bian, XY; Chen, C; Jiang, H; Li, J; Liu, HL; Liu, SJ; Liu, YF; Shan, JJ; Si, ZL; Tan, NH; Wang, H; Wu, WH; Zhang, ZH; Zhou, W, 2022) |
| "Renal interstitial fibrosis is characterized by the development of myofibroblasts, originating from resident renal and immigrating cells." | 1.62 | Endothelin receptors in renal interstitial cells do not contribute to the development of fibrosis during experimental kidney disease. ( Broeker, KAE; Fuchs, MAA; Neder, TH; Schrankl, J; Wagner, C, 2021) |
| "Renal fibrosis is an inevitable course of all kinds of progressive chronic kidney disease (CKD)." | 1.56 | 4-Octyl itaconate protects against renal fibrosis via inhibiting TGF-β/Smad pathway, autophagy and reducing generation of reactive oxygen species. ( He, J; Tan, N; Tian, F; Wang, Z; Zhang, Z, 2020) |
| "Renal fibrosis is a common pathological feature of the progression of chronic kidney disease." | 1.46 | Valproic acid attenuates renal fibrosis through the induction of autophagy. ( Doi, S; Doi, T; Kawaoka, K; Masaki, T; Nakashima, A; Ueno, T; Yamada, K, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 9 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, W | 2 |
| Chen, MM | 1 |
| Liu, HL | 2 |
| Si, ZL | 2 |
| Wu, WH | 2 |
| Jiang, H | 2 |
| Wang, LX | 1 |
| Vaziri, ND | 1 |
| An, XF | 1 |
| Su, K | 1 |
| Chen, C | 2 |
| Tan, NH | 2 |
| Zhang, ZH | 2 |
| Liu, Z | 1 |
| Wang, W | 1 |
| Li, X | 1 |
| Tang, S | 1 |
| Meng, D | 1 |
| Xia, W | 1 |
| Wang, H | 3 |
| Wu, Y | 1 |
| Zhou, X | 1 |
| Zhang, J | 1 |
| Du, P | 1 |
| Wang, T | 1 |
| Yang, M | 1 |
| Yin, H | 1 |
| Nakayama, T | 1 |
| Azegami, T | 1 |
| Hayashi, K | 1 |
| Hishikawa, A | 1 |
| Yoshimoto, N | 1 |
| Nakamichi, R | 1 |
| Sugita, E | 1 |
| Itoh, H | 1 |
| Liu, YF | 1 |
| Alolga, RN | 1 |
| Liu, SJ | 1 |
| Bian, XY | 1 |
| Shan, JJ | 1 |
| Li, J | 1 |
| Tian, F | 1 |
| Wang, Z | 1 |
| He, J | 1 |
| Zhang, Z | 1 |
| Tan, N | 1 |
| Eckes, T | 1 |
| Trautmann, S | 1 |
| Djudjaj, S | 1 |
| Beyer, S | 1 |
| Patyna, S | 1 |
| Schwalm, S | 1 |
| Gauer, S | 1 |
| Thomas, D | 1 |
| Schaefer, L | 1 |
| Boor, P | 2 |
| Koch, A | 1 |
| Pfeilschifter, J | 1 |
| Son, SS | 1 |
| Hwang, S | 1 |
| Park, JH | 1 |
| Ko, Y | 1 |
| Yun, SI | 1 |
| Lee, JH | 1 |
| Son, B | 1 |
| Kim, TR | 1 |
| Park, HO | 1 |
| Lee, EY | 1 |
| Neder, TH | 1 |
| Schrankl, J | 1 |
| Fuchs, MAA | 1 |
| Broeker, KAE | 1 |
| Wagner, C | 1 |
| Buchtler, S | 1 |
| Grill, A | 1 |
| Hofmarksrichter, S | 1 |
| Stöckert, P | 1 |
| Schiechl-Brachner, G | 1 |
| Rodriguez Gomez, M | 1 |
| Neumayer, S | 1 |
| Schmidbauer, K | 1 |
| Talke, Y | 1 |
| Klinkhammer, BM | 1 |
| Medvinsky, A | 1 |
| Renner, K | 1 |
| Castrop, H | 1 |
| Mack, M | 1 |
| Kawaoka, K | 1 |
| Doi, S | 1 |
| Nakashima, A | 1 |
| Yamada, K | 1 |
| Ueno, T | 1 |
| Doi, T | 1 |
| Masaki, T | 1 |
| Kim, WY | 1 |
| Nam, SA | 1 |
| Song, HC | 1 |
| Ko, JS | 1 |
| Park, SH | 1 |
| Kim, HL | 1 |
| Choi, EJ | 1 |
| Kim, YS | 1 |
| Kim, J | 1 |
| Kim, YK | 1 |
12 other studies available for adenine and Ureteral Obstruction
| Article | Year |
|---|---|
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho.
Topics: Adenine; Animals; Artemisinins; Azacitidine; beta Catenin; Biotin; DNA; DNA Modification Methylases; | 2022 |
Capsaicin ameliorates renal fibrosis by inhibiting TGF-β1-Smad2/3 signaling.
Topics: Adenine; Animals; Cadherins; Capsaicin; Disease Models, Animal; Fibrosis; Kidney; Kidney Diseases; M | 2022 |
Mucin-fused myeloid-derived growth factor (MYDGF164) exhibits a prolonged serum half-life and alleviates fibrosis in chronic kidney disease.
Topics: Adenine; Animals; Disease Models, Animal; Fibrosis; Half-Life; Humans; Intercellular Signaling Pepti | 2022 |
Vaccination against connective tissue growth factor attenuates the development of renal fibrosis.
Topics: Adenine; Animals; Connective Tissue Growth Factor; Fibrosis; Kidney; Kidney Diseases; Mice; Renal In | 2022 |
The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice.
Topics: Adenine; Animals; Bacteroides fragilis; Biological Products; Disease Models, Animal; Fibrosis; Gastr | 2022 |
4-Octyl itaconate protects against renal fibrosis via inhibiting TGF-β/Smad pathway, autophagy and reducing generation of reactive oxygen species.
Topics: Adenine; Animals; Antioxidants; Autophagy; Fibrosis; Humans; Kidney Diseases; Male; Protective Agent | 2020 |
Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys.
Topics: Actins; Adenine; Aged; Animals; Biomarkers; Ceramides; Collagen Type I; Collagen Type I, alpha 1 Cha | 2021 |
In vivo silencing of amphiregulin by a novel effective Self-Assembled-Micelle inhibitory RNA ameliorates renal fibrosis via inhibition of EGFR signals.
Topics: Adenine; Amphiregulin; Animals; Cell Adhesion Molecules; Cytokines; Diet; Disease Models, Animal; Do | 2021 |
Endothelin receptors in renal interstitial cells do not contribute to the development of fibrosis during experimental kidney disease.
Topics: Adenine; Animals; Fibrosis; Gene Deletion; Gene Expression Regulation; Kidney; Kidney Diseases; Mice | 2021 |
Cellular Origin and Functional Relevance of Collagen I Production in the Kidney.
Topics: Acute Kidney Injury; Adenine; Animals; Bone Marrow Cells; Cell Lineage; Collagen Type I; Epithelial | 2018 |
Valproic acid attenuates renal fibrosis through the induction of autophagy.
Topics: Actins; Adenine; Animals; Autophagy; Cell Line; Collagen Type I; Cytoprotection; Disease Models, Ani | 2017 |
The role of autophagy in unilateral ureteral obstruction rat model.
Topics: Adenine; Animals; Apoptosis; Autophagy; Cell Proliferation; Cytoprotection; Disease Models, Animal; | 2012 |