adenine has been researched along with Tay-Sachs Disease in 1 studies
Tay-Sachs Disease: An autosomal recessive neurodegenerative disorder characterized by the onset in infancy of an exaggerated startle response, followed by paralysis, dementia, and blindness. It is caused by mutation in the alpha subunit of the HEXOSAMINIDASE A resulting in lipid-laden ganglion cells. It is also known as the B variant (with increased HEXOSAMINIDASE B but absence of hexosaminidase A) and is strongly associated with Ashkenazic Jewish ancestry.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akli, S | 1 |
| Chelly, J | 1 |
| Mezard, C | 1 |
| Gandy, S | 1 |
| Kahn, A | 1 |
| Poenaru, L | 1 |
1 other study available for adenine and Tay-Sachs Disease
| Article | Year |
|---|---|
A "G" to "A" mutation at position -1 of a 5' splice site in a late infantile form of Tay-Sachs disease.
Topics: Adenine; Base Sequence; beta-N-Acetylhexosaminidases; Blotting, Northern; Cells, Cultured; DNA; Exon | 1990 |