adenine has been researched along with T-Cell Lymphoma in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The majority of peripheral T-cell lymphomas were found to lack methylthioadenosine phosphorylase, an enzyme that is essential for the salvage of adenine from methylthioadenosine, a product of polyamine synthesis." | 3.78 | Lack of expression of MTAP in uncommon T-cell lymphomas. ( Bertino, JR; Bhagavathi, S; Chan, WC; Goodell, L; Johnson-Farley, N; Lubin, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ping, L | 1 |
| Ding, N | 1 |
| Shi, Y | 1 |
| Feng, L | 1 |
| Li, J | 1 |
| Liu, Y | 1 |
| Lin, Y | 1 |
| Shi, C | 1 |
| Wang, X | 1 |
| Pan, Z | 1 |
| Song, Y | 1 |
| Zhu, J | 2 |
| Kumar, A | 1 |
| Vardhana, S | 1 |
| Moskowitz, AJ | 1 |
| Porcu, P | 1 |
| Dogan, A | 1 |
| Dubovsky, JA | 1 |
| Matasar, MJ | 1 |
| Zhang, Z | 1 |
| Younes, A | 1 |
| Horwitz, SM | 1 |
| Grommes, C | 1 |
| Nayak, L | 1 |
| Tun, HW | 1 |
| Batchelor, TT | 1 |
| He, S | 1 |
| Du, J | 1 |
| Wang, Z | 1 |
| Li, W | 1 |
| Chen, X | 1 |
| Jiang, W | 1 |
| Zheng, D | 1 |
| Jin, G | 1 |
| Wang, T | 1 |
| Lu, Y | 1 |
| Polk, A | 1 |
| Chowdhury, P | 1 |
| Murga-Zamalloa, C | 1 |
| Fujiwara, H | 1 |
| Suemori, K | 1 |
| Beyersdorf, N | 1 |
| Hristov, AC | 1 |
| Lim, MS | 1 |
| Bailey, NG | 1 |
| Wilcox, RA | 1 |
| Otová, B | 2 |
| Hrdy, J | 1 |
| Votruba, I | 2 |
| Holy, A | 2 |
| Bertino, JR | 1 |
| Lubin, M | 1 |
| Johnson-Farley, N | 1 |
| Chan, WC | 1 |
| Goodell, L | 1 |
| Bhagavathi, S | 1 |
| Mráz, M | 1 |
| Mandys, V | 1 |
| Panczak, A | 1 |
| Schramlová, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter Phase I Study of Ibrutinib in Relapsed and Refractory T-cell Lymphoma[NCT02309580] | Phase 1 | 14 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for adenine and T-Cell Lymphoma
| Article | Year |
|---|---|
Introduction of novel agents in the treatment of primary CNS lymphoma.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Aminopyridines; Antineoplastic Agents, Immunological; | 2019 |
1 trial available for adenine and T-Cell Lymphoma
| Article | Year |
|---|---|
Pilot trial of ibrutinib in patients with relapsed or refractory T-cell lymphoma.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Female; Humans; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneo | 2018 |
6 other studies available for adenine and T-Cell Lymphoma
| Article | Year |
|---|---|
The Bruton's tyrosine kinase inhibitor ibrutinib exerts immunomodulatory effects through regulation of tumor-infiltrating macrophages.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Chem | 2017 |
Local administration of a novel Toll-like receptor 7 agonist in combination with doxorubicin induces durable tumouricidal effects in a murine model of T cell lymphoma.
Topics: Adenine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blotting, W | 2015 |
T-cell Receptor Signaling Activates an ITK/NF-κB/GATA-3 axis in T-cell Lymphomas Facilitating Resistance to Chemotherapy.
Topics: Adenine; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; GATA3 Transcription Factor | 2017 |
In vivo modulation of angiogenic gene expression by acyclic nucleoside phosphonates PMEDAP and PMEG.
Topics: Adenine; Animals; Epidermal Growth Factor; ErbB Receptors; Fibroblast Growth Factor 1; Gene Expressi | 2009 |
Lack of expression of MTAP in uncommon T-cell lymphomas.
Topics: Adenine; Aminopterin; Folic Acid Antagonists; Humans; Lymphoma, T-Cell; Purine-Nucleoside Phosphoryl | 2012 |
Therapeutic effect of heat shock on T-cell lymphoma in inbred Sprague-Dawley rat.
Topics: Adenine; Animals; Antimetabolites, Antineoplastic; Apoptosis; Body Weight; Combined Modality Therapy | 1999 |