adenine has been researched along with Sarcoma in 12 studies
Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The activity of amonafide, a benzisoquinoline-1,3-dione, was assessed in 15 patients with advanced or recurrent sarcoma (11 previously treated)." | 9.07 | Phase II study of amonafide in advanced and recurrent sarcoma patients. ( Comis, RL; Nash, SL; O'Dwyer, PJ; Ozols, RF; Perez, RP, 1992) |
| "Amonafide was administered to 18 patients with advanced soft tissue sarcoma (16 of whom had received prior chemotherapy) at a dose of 300 mg/m2 over 60 min daily for 5 days." | 6.67 | Phase II evaluation of amonafide in advanced sarcoma: a Southwest Oncology Group study. ( Balcerzak, SP; Buys, SS; Metch, B; Neefe, JR; Stuckey, WJ, 1994) |
| "The activity of amonafide, a benzisoquinoline-1,3-dione, was assessed in 15 patients with advanced or recurrent sarcoma (11 previously treated)." | 5.07 | Phase II study of amonafide in advanced and recurrent sarcoma patients. ( Comis, RL; Nash, SL; O'Dwyer, PJ; Ozols, RF; Perez, RP, 1992) |
| "Amonafide was administered to 18 patients with advanced soft tissue sarcoma (16 of whom had received prior chemotherapy) at a dose of 300 mg/m2 over 60 min daily for 5 days." | 2.67 | Phase II evaluation of amonafide in advanced sarcoma: a Southwest Oncology Group study. ( Balcerzak, SP; Buys, SS; Metch, B; Neefe, JR; Stuckey, WJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Q | 1 |
| Orlando, EJ | 1 |
| Wang, HY | 1 |
| Bogusz, AM | 1 |
| Liu, X | 1 |
| Lacey, SF | 1 |
| Strauser, HT | 1 |
| Nunez-Cruz, S | 1 |
| Nejati, R | 1 |
| Zhang, P | 1 |
| Brooks, S | 1 |
| Watt, C | 1 |
| Melenhorst, JJ | 1 |
| June, CH | 1 |
| Schuster, SJ | 1 |
| Wasik, MA | 1 |
| Li, GD | 1 |
| Kawashima, H | 1 |
| Ogose, A | 1 |
| Ariizumi, T | 1 |
| Hotta, T | 1 |
| Kuwano, R | 1 |
| Urata, Y | 1 |
| Fujiwara, T | 1 |
| Endo, N | 1 |
| WAY, JL | 1 |
| MANDEL, HG | 1 |
| SMITH, PK | 1 |
| COSTAKEL, O | 1 |
| CERECEDO, LR | 1 |
| SMITH, MJ | 1 |
| VICENTE, J | 1 |
| MANOILOV, SE | 1 |
| KITAVIN, GS | 1 |
| COMAR, VE | 1 |
| ORLOVA, EU | 1 |
| FURTH, JJ | 1 |
| HO, P | 1 |
| Hines, ER | 1 |
| Kolek, OI | 1 |
| Jones, MD | 1 |
| Serey, SH | 1 |
| Sirjani, NB | 1 |
| Kiela, PR | 1 |
| Jurutka, PW | 1 |
| Haussler, MR | 1 |
| Collins, JF | 1 |
| Ghishan, FK | 1 |
| Buys, SS | 1 |
| Metch, B | 1 |
| Balcerzak, SP | 1 |
| Neefe, JR | 1 |
| Stuckey, WJ | 1 |
| Fuska, J | 1 |
| Proksa, B | 1 |
| Fusková, A | 1 |
| Perez, RP | 1 |
| Nash, SL | 1 |
| Ozols, RF | 1 |
| Comis, RL | 1 |
| O'Dwyer, PJ | 1 |
| Jeffery, WR | 1 |
| Brawerman, G | 1 |
2 trials available for adenine and Sarcoma
| Article | Year |
|---|---|
Phase II evaluation of amonafide in advanced sarcoma: a Southwest Oncology Group study.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Imides; | 1994 |
Phase II study of amonafide in advanced and recurrent sarcoma patients.
Topics: Adenine; Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Female; | 1992 |
10 other studies available for adenine and Sarcoma
| Article | Year |
|---|---|
Transdifferentiation of lymphoma into sarcoma associated with profound reprogramming of the epigenome.
Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Cell Transdifferentiation; Cellular Reprogr | 2020 |
Telomelysin shows potent antitumor activity through apoptotic and non-apoptotic cell death in soft tissue sarcoma cells.
Topics: Adenine; Adenosine Triphosphate; Adenoviridae; Adenoviridae Infections; Antineoplastic Agents; Apopt | 2013 |
The effects of tumor growth, x-radiation, and 8-azaguanine on the incorporation of adenine into nucleic acids of mice.
Topics: Adenine; Animals; Azaguanine; Guanine; Mice; Neoplasms; Nucleic Acids; Sarcoma; X-Rays | 1954 |
THE CHEMOTHERAPY OF CANCER WITH MASSIVE DOSES UNDER THE PROTECTION OF PERFUSION OF AUTOGENOUS HEMATOPOIETIC TISSUE.
Topics: Adenine; Bone Marrow Transplantation; Breast Neoplasms; DNA; Female; Folic Acid; Humans; Lung Neopla | 1964 |
TUMOR-HOST RELATIONSHIPS STUDIED IN VITRO: EXPERIMENTS WITH TISSUE SLICES.
Topics: Adenine; Carcinoma 256, Walker; DNA; In Vitro Techniques; Kidney; Liver; Lung; Lymphoma, Non-Hodgkin | 1964 |
ON THE OXIDATIVE PHOSPHORYLATION AND NUCLEIC ACIDS METABOLISM IN SOME ORGANS OF ANIMALS WITH TRANSPLANTABLE TUMOURS.
Topics: Adenine; Carbohydrate Metabolism; Cytosine; DNA; DNA, Neoplasm; Glycolysis; Guanine; Intestines; Kid | 1964 |
THE ENZYMATIC SYNTHESIS OF RIBONUCLEIC ACID IN ANIMAL TISSUE. I. THE DEOXYRIBONUCLEIC ACID-DIRECTED SYNTHESIS OF RIBONUCLEIC ACID AS CATALYZED BY AN ENZYME OBTAINED FROM BOVINE LYMPHOSARCOMA TISSUE.
Topics: Adenine; Animals; Catalysis; Cattle; Cytosine; DNA; DNA Replication; DNA, Bacterial; Enzootic Bovine | 1965 |
1,25-dihydroxyvitamin D3 down-regulation of PHEX gene expression is mediated by apparent repression of a 110 kDa transfactor that binds to a polyadenine element in the promoter.
Topics: Adenine; Animals; Base Sequence; Binding Sites; Blotting, Northern; Blotting, Southern; Blotting, We | 2004 |
New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors.
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; In Vitro Techniques; Leu | 1975 |
Characterization of the steady-state population of messenger RNA and its poly(adenylic acid) segment in mammalian cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Base Sequence; Carbon Radioisotopes; Centrifugatio | 1974 |