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adenine and Sarcoma 180

adenine has been researched along with Sarcoma 180 in 25 studies

Sarcoma 180: An experimental sarcoma of mice.

Research Excerpts

ExcerptRelevanceReference
"The effects of the chiral isomers of erythro- and threo-9-(2-hydroxy-3-nonyl)adenines (EHNA and THNA) on purine metabolism in Sarcoma 180 cells have been determined."7.66Effects of the chiral isomers of erythro- and threo-9-(2-hydroxy-3-nonyl)adenine on purine metabolism in sarcoma 180 cells. ( Abushanab, E; Berman, SF; Burgess, FW; Chen, SF; Choi, HS; Marcaccio, EJ; Panzica, RP; Parks, RE; Steen, PA; Stoeckler, JD, 1982)
"-) activity present in Sarcoma 180 cells grown in culture and in rat liver, is shown to be distinct from inosine-guanosine phosphorylase by several criteria: (a) treatment of Sarcoma 180 cell extract with p-chloromercuribenzoate inhibited the two activities to a different extent, (b) adenine selectively protected the adenosine phosphorylase activity of Sarcoma 180 and rat liver extract against heat inactivation, while hypoxanthine selectively protected inosine-guanosine phosphorylase activity, (c) at nearly saturating substrate concentrations and using Sarcoma 180 extract, the rates of ribosylation of a mixture of adenine + hypoxanthine or adenine + guanine, but not of hypoxanthine + guanine, were found to be almost equal to the sum of their individual rates as measured separately, (d) inosine selectively inhibited the ribosylation of hypoxanthine and guanine catalysed by Sarcoma 180 and rat liver extract while 2-chloroadenosine selectively inhibited the ribosylation of adenine and N6-furfuryladenine, (e) pH vs."7.65Adenosine phosphyorylase activity as distinct from inosine-guanosine phosphorylase activity in Sarcoma 180 cells and rat liver. ( Divekar, AY, 1976)
"The effects of the chiral isomers of erythro- and threo-9-(2-hydroxy-3-nonyl)adenines (EHNA and THNA) on purine metabolism in Sarcoma 180 cells have been determined."3.66Effects of the chiral isomers of erythro- and threo-9-(2-hydroxy-3-nonyl)adenine on purine metabolism in sarcoma 180 cells. ( Abushanab, E; Berman, SF; Burgess, FW; Chen, SF; Choi, HS; Marcaccio, EJ; Panzica, RP; Parks, RE; Steen, PA; Stoeckler, JD, 1982)
"-) activity present in Sarcoma 180 cells grown in culture and in rat liver, is shown to be distinct from inosine-guanosine phosphorylase by several criteria: (a) treatment of Sarcoma 180 cell extract with p-chloromercuribenzoate inhibited the two activities to a different extent, (b) adenine selectively protected the adenosine phosphorylase activity of Sarcoma 180 and rat liver extract against heat inactivation, while hypoxanthine selectively protected inosine-guanosine phosphorylase activity, (c) at nearly saturating substrate concentrations and using Sarcoma 180 extract, the rates of ribosylation of a mixture of adenine + hypoxanthine or adenine + guanine, but not of hypoxanthine + guanine, were found to be almost equal to the sum of their individual rates as measured separately, (d) inosine selectively inhibited the ribosylation of hypoxanthine and guanine catalysed by Sarcoma 180 and rat liver extract while 2-chloroadenosine selectively inhibited the ribosylation of adenine and N6-furfuryladenine, (e) pH vs."3.65Adenosine phosphyorylase activity as distinct from inosine-guanosine phosphorylase activity in Sarcoma 180 cells and rat liver. ( Divekar, AY, 1976)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199023 (92.00)18.7374
1990's1 (4.00)18.2507
2000's0 (0.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, X1
Liu, Q1
Wang, Z1
Wang, P1
Zhao, P1
Zhao, X1
Yang, L1
Li, Y1
SARTORELLI, AC8
UPCHURCH, HF2
BIEBER, AL3
CHANG, PK1
FISCHER, GA1
DYER, E1
REITZ, JM1
FARRIS, RE1
BOOTH, BA4
SATO, K1
LEPAGE, GA1
Watson, JD2
Ralph, RK2
Chen, SF1
Stoeckler, JD1
Choi, HS1
Burgess, FW1
Marcaccio, EJ1
Steen, PA1
Berman, SF1
Parks, RE2
Panzica, RP1
Abushanab, E2
Adachi, T1
Arai, Y1
Inoue, I1
Saneyoshi, M1
Dutta, SP1
Mittelman, A1
Chheda, GB1
Divekar, AY1
Jeffery, WR1
Brawerman, G1
Savarese, TM1
Harrington, S1
Nakamura, C1
Chen, ZH1
Kumar, P1
Mikkilineni, A1
Chu, SH1
Agrawal, KC1
Michaud, RL1
Moore, EC2
Scholar, EM1
Calabresi, P1
Zimmerman, TP1
Gersten, NB1
Ross, AF1
Miech, RP1
Dixon, GJ1
Dulmadge, EA1
Brockman, RW1
Shaddix, SC1
Sartoreli, AC1
Anderson, JH1
Cramer, GT1
Otsuka, H1
Adams, DH1
Bowman, BM1

Other Studies

25 other studies available for adenine and Sarcoma 180

ArticleYear
Role of autophagy in sonodynamic therapy-induced cytotoxicity in S180 cells.
    Ultrasound in medicine & biology, 2010, Volume: 36, Issue:11

    Topics: Adenine; Analysis of Variance; Animals; Apoptosis; Autophagy; Blotting, Western; Caspase 3; Cell Lin

2010
PHYSIOLOGICAL DISPOSITION AND THERAPEUTIC CONSEQUENCES OF ADENINE ADMINISTERED VIA THE GASTROINTESTINAL TRACT IN NORMAL AND TUMOR-BEARING MICE.
    Cancer research, 1963, Volume: 23

    Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatoc

1963
SOME INHIBITORY PROPERTIES OF 6-N-HYDROXYLAMINOPURINE: AN ANALOG OF ADENINE AND HYPOXANTHINE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Adenine; Adenine Nucleotides; Animals; Antimetabolites; Carbon Isotopes; Glycine; Guanine Nucleotide

1964
CARBAMATES DERIVED FROM AMINOPURINES.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: 2-Aminopurine; Adenine; Animals; Antineoplastic Agents; Carbamates; Chemistry, Pharmaceutical; Leuke

1963
SOME METABOLIC EFFECTS EXERTED BY AZASERINE AND PURINE ANALOGS IN VIVO.
    Cancer research, 1964, Volume: 24

    Topics: Adenine; Amino Acids; Animals; Antimetabolites; Antineoplastic Agents; Azaserine; Carbon Isotopes; G

1964
THE METABOLISM OF THIOGUANINE IN PURINE ANALOG-RESISTANT CELLS.
    Cancer research, 1964, Volume: 24

    Topics: Adenine; Animals; Antimetabolites; Antineoplastic Agents; Cell Biology; DNA; DNA, Neoplasm; Guanine;

1964
METABOLIC EFFECTS OF AN ANTIBIOTIC, NSC-51954, ON SUSCEPTIBLE AND RESISTANT TUMOR CELLS.
    Cancer research, 1965, Volume: 25

    Topics: Adenine; Animals; Anti-Bacterial Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA; DNA, Neopla

1965
Effect of chelating agents upon the synthesis of nucleic acids and protein: inhibition of DNA synthesis by 1-formylisoquinoline thiosemicarbazone.
    Biochemical and biophysical research communications, 1967, Apr-07, Volume: 27, Issue:1

    Topics: Adenine; Animals; Antimetabolites; Carbon Isotopes; Chelating Agents; DNA, Neoplasm; Formates; Leuci

1967
DNA-associated RNA from sarcoma 180 cells.
    Biochimica et biophysica acta, 1967, Mar-29, Volume: 138, Issue:1

    Topics: Adenine; Animals; Cytosine; Dactinomycin; DNA, Neoplasm; Guanine; Kinetics; Mice; Nucleotidyltransfe

1967
Effects of the chiral isomers of erythro- and threo-9-(2-hydroxy-3-nonyl)adenine on purine metabolism in sarcoma 180 cells.
    Biochemical pharmacology, 1982, Dec-15, Volume: 31, Issue:24

    Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Glycine; Guanosine; Hypoxanthines; Inosine; Mice;

1982
Synthesis and antitumor activity of cytosine and adenine nucleosides of unsaturated 5-(aminoacyl)aminopentofuranoses.
    Carbohydrate research, 1980, Jan-01, Volume: 78, Issue:1

    Topics: Adenine; Amino Acids; Animals; Antineoplastic Agents; Cytosine; Leukemia L1210; Mice; Sarcoma 180

1980
Metabolism of 1,N6-ethenoadenosine.
    Biochemical medicine, 1980, Volume: 23, Issue:2

    Topics: Adenine; Adenosine; Animals; Cells, Cultured; Leukemia L1210; Male; Mice; Rats; Sarcoma 180

1980
Adenosine phosphyorylase activity as distinct from inosine-guanosine phosphorylase activity in Sarcoma 180 cells and rat liver.
    Biochimica et biophysica acta, 1976, Jan-23, Volume: 422, Issue:1

    Topics: Adenine; Adenosine; Animals; Chloromercuribenzoates; Guanine; Hydrogen-Ion Concentration; Inosine; K

1976
Association of the polyadenylate segment of messenger RNA with other polynucleotide sequences in mouse sarcoma 180 polyribosomes.
    Biochemistry, 1975, Jul-29, Volume: 14, Issue:15

    Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Base Sequence; Chromatography, Affinity; Hypoxanth

1975
5'-deoxy-5'-methylthioadenosine phosphorylase--V. Acycloadenosine derivatives as inhibitors of the enzyme.
    Biochemical pharmacology, 1990, Dec-01, Volume: 40, Issue:11

    Topics: Adenine; Animals; Antineoplastic Agents; Female; Kinetics; Mice; Purine-Nucleoside Phosphorylase; Sa

1990
Comparative studies of the antineoplastic activity of 5-hydroxy-2-formylpyridine thiosemicarbazone and its seleno-semicarbazone, guanylhydrazone and semicarbazone analogs.
    Biochemical pharmacology, 1974, Sep-01, Volume: 23, Issue:17

    Topics: Adenine; Animals; Antineoplastic Agents; Carbon Radioisotopes; Cobalt; Cytidine; DNA, Neoplasm; Guan

1974
Identification of the enzymatic pathways of nucleotide metabolism in human lymphocytes and leukemia cells.
    Cancer research, 1973, Volume: 33, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Aminohydrolases; Animals; Cell Fractionation; Cell Line; Ch

1973
Adenine as substrate for purine nucleoside phosphorylase.
    Canadian journal of biochemistry, 1971, Volume: 49, Issue:9

    Topics: Adenine; Animals; Brain; Carbon Isotopes; Chick Embryo; Chromatography, Gel; Chromatography, Paper;

1971
Feedback inhibition of purine biosynthesis in adenocarcinoma 755 and sarcoma 180 cells in culture.
    Journal of the National Cancer Institute, 1970, Volume: 45, Issue:4

    Topics: Adenine; Adenocarcinoma; Animals; Azaserine; Carbon Isotopes; Cell Line; Feedback; Hypoxanthines; Me

1970
Metabolic effects of some tumor-inhibitory pyridine carboxaldehyde thiosemicarbazones.
    Cancer research, 1971, Volume: 31, Issue:3

    Topics: Adenine; Aldehydes; Animals; Antineoplastic Agents; Ascitic Fluid; Carbon Isotopes; Cell Count; DNA,

1971
Alterations in purine nucleotide biosynthesis induced by 2-amino-6-chloropurine.
    Biochemical pharmacology, 1968, Volume: 17, Issue:1

    Topics: Adenine; Adenine Nucleotides; Amides; Animals; Antineoplastic Agents; Carbon Isotopes; Chlorine; Fem

1968
Studies on the mechanism of the azaserine-induced decrease in the activity of thymidine kinase.
    Biochemical pharmacology, 1969, Volume: 18, Issue:6

    Topics: Adenine; Animals; Azaserine; Carbon Isotopes; Female; Mice; Nucleosides; Nucleotides; Sarcoma 180; T

1969
Mechanism of inhibition of DNA synthesis of sarcoma 180 cells by liver extract.
    Cancer research, 1969, Volume: 29, Issue:9

    Topics: Adenine; Animals; Cattle; Copper; Cytosine Nucleotides; DNA, Neoplasm; In Vitro Techniques; Liver; M

1969
Studies on the properties of factors elevating the activity of mouse-plasma lactate dehydrogenase.
    The Biochemical journal, 1964, Volume: 90, Issue:3

    Topics: Adenine; Animals; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Enzymes; Guanine; In

1964
Changes in RNA synthesis following transfer of Sarcoma 180 ascites cells from the mouse to synthetic medium.
    Cancer research, 1966, Volume: 26, Issue:11

    Topics: Adenine; Animals; Chromatography; Culture Techniques; Cytosine; Guanine; Mice; Phosphorus Isotopes;

1966