Page last updated: 2024-10-16

adenine and Puberty, Precocious

adenine has been researched along with Puberty, Precocious in 1 studies

Puberty, Precocious: Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.

Research Excerpts

Excerpt	Relevance	Reference
"Familial male precocious puberty (FMPP) is a gonadotropin-independent disorder that is inherited in an autosomal dominant, male-limited pattern."	1.29	A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty. ( Cutler, GB; Kosugi, S; Laue, L; Merendino, JJ; Minegishi, T; Shenker, A, 1993)

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Shenker, A	1
Laue, L	1
Kosugi, S	1
Merendino, JJ	1
Minegishi, T	1
Cutler, GB	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Spironolactone and Testolactone Treatment of Boys With Familial Isosexual Precocious Puberty[NCT00001202]			Phase 2	80 participants	Interventional	1985-01-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for adenine and Puberty, Precocious

Article	Year
A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty. Nature, 1993, Oct-14, Volume: 365, Issue:6447 Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chorionic Gonadotropin; Cyclic AMP;	1993