adenine has been researched along with Polycythemia Vera in 2 studies
Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
Excerpt | Relevance | Reference |
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"Erythrocytes of patients with polycythemia vera exhibited increased activity of oxidative pentose shunt, accelerated generation of phosphoribosylpyrophosphate, increased incorporation of 14C-adenine into nucleotides, and increased activity and thermostability of adenine-phosphoribosyltransferase." | 3.65 | Pentose shunt, phosphoribosylpyrophosphate generation and purine-phosphoribosyltransferases in erythrocytes of patients with polycythemia vera. ( Boer, P; Brosh, S; de Vries, A; Elazar, E; Pinkhas, J; Sperling, O; Szeinberg, A, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sperling, O | 1 |
Boer, P | 1 |
Brosh, S | 1 |
Elazar, E | 1 |
Pinkhas, J | 1 |
Szeinberg, A | 1 |
de Vries, A | 1 |
Schöch, G | 1 |
Garbrecht, M | 1 |
Heller-Schöch, G | 1 |
Baisch, H | 1 |
Leifer, W | 1 |
2 other studies available for adenine and Polycythemia Vera
Article | Year |
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Pentose shunt, phosphoribosylpyrophosphate generation and purine-phosphoribosyltransferases in erythrocytes of patients with polycythemia vera.
Topics: Adenine; Adenine Phosphoribosyltransferase; Aging; Erythrocytes; Hot Temperature; Humans; Hypoxanthi | 1975 |
[Normal and modified nucleobases excreted in urine of patients with chronic nyeloproliferative disorders (author's transl)].
Topics: Adenine; Adult; Aged; Female; Guanine; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged | 1979 |