Page last updated: 2024-10-16

adenine and P carinii Pneumonia

adenine has been researched along with P carinii Pneumonia in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, R1
Nayernama, A1
Jones, SC1
Wroblewski, T1
Waldron, PE1
Cheng, MP1
Kusztos, AE1
Gustine, JN1
Dryden-Peterson, SL1
Dubeau, TE1
Woolley, AE1
Hammond, SP1
Baden, LR1
Treon, SP1
Castillo, JJ1
Issa, NC1
Ahn, IE1
Jerussi, T1
Farooqui, M1
Tian, X1
Wiestner, A1
Gea-Banacloche, J1
Romero, E1
Hernández, JM1
Jarilla, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)[NCT02514083]Phase 229 participants (Actual)Interventional2015-12-09Active, not recruiting
A Phase II Study of PCI-32765 for Patients With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Who Need Therapy and Are Older Than 65 or Have a 17p Deletion[NCT01500733]Phase 286 participants (Actual)Interventional2012-01-05Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Response Rate at 6 Months

"The primary endpoint was response after 6 cycles of therapy. Overall response rate was calculated as complete response plus partial response, based on the International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2008 criteria.as follows:~Complete response (CR): all group A and group B criteria are met~Group A criteria: resolution of enlarged lymph nodes, normal size spleen and liver, absolute lymphocyte count < 4,000/uL, normocellular bone marrow with < 30% lymphocytes without nodules~Group B criteria: improved blood count (platelet count > 100,000/uL, hemoglobin > 11.0 g/dL, neutrophils > 1,500/uL)~Partial response (PR): at least 2 of the group A criteria plus one of the group B criteria are met~Group A criteria: >=50% decrease in target lymph nodes, >=50% decrease in spleen size, >=50% decrease in liver size, 50% reduction in marrow infiltrates~Group B criteria: platelet count > 100,000/uL, hemoglobin > 11.0 g/dL, neutrophils > 1,500/uL" (NCT01500733)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Elderly Cohort93.9
TP53 Cohort95.8

Trials

1 trial available for adenine and P carinii Pneumonia

ArticleYear
Atypical Pneumocystis jirovecii pneumonia in previously untreated patients with CLL on single-agent ibrutinib.
    Blood, 2016, 10-13, Volume: 128, Issue:15

    Topics: Adenine; Aged; Follow-Up Studies; Humans; Incidence; Leukemia, Lymphocytic, Chronic, B-Cell; Male; P

2016
Atypical Pneumocystis jirovecii pneumonia in previously untreated patients with CLL on single-agent ibrutinib.
    Blood, 2016, 10-13, Volume: 128, Issue:15

    Topics: Adenine; Aged; Follow-Up Studies; Humans; Incidence; Leukemia, Lymphocytic, Chronic, B-Cell; Male; P

2016
Atypical Pneumocystis jirovecii pneumonia in previously untreated patients with CLL on single-agent ibrutinib.
    Blood, 2016, 10-13, Volume: 128, Issue:15

    Topics: Adenine; Aged; Follow-Up Studies; Humans; Incidence; Leukemia, Lymphocytic, Chronic, B-Cell; Male; P

2016
Atypical Pneumocystis jirovecii pneumonia in previously untreated patients with CLL on single-agent ibrutinib.
    Blood, 2016, 10-13, Volume: 128, Issue:15

    Topics: Adenine; Aged; Follow-Up Studies; Humans; Incidence; Leukemia, Lymphocytic, Chronic, B-Cell; Male; P

2016

Other Studies

3 other studies available for adenine and P carinii Pneumonia

ArticleYear
Ibrutinib-associated Pneumocystis jirovecii pneumonia.
    American journal of hematology, 2017, Volume: 92, Issue:11

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Piperidines; Pneumocysti

2017
Low risk of Pneumocystis jirovecii pneumonia and invasive aspergillosis in patients with Waldenström macroglobulinaemia on ibrutinib.
    British journal of haematology, 2019, Volume: 185, Issue:4

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Invasive Fungal Infe

2019
[Renal tuberculosis and human immunodeficiency virus infection].
    Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:6

    Topics: Acute Kidney Injury; Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral

2009