adenine has been researched along with Neuronal Ceroid-Lipofuscinoses in 2 studies
Neuronal Ceroid-Lipofuscinoses: A group of severe neurodegenerative diseases characterized by intracellular accumulation of autofluorescent wax-like lipid materials (CEROID; LIPOFUSCIN) in neurons. There are several subtypes based on mutations of the various genes, time of disease onset, and severity of the neurological defects such as progressive DEMENTIA; SEIZURES; and visual failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Infantile neuronal ceroid lipofuscinosis (INCL) is a severe neurodegenerative disorder of the childhood caused by mutations in the gene encoding palmitoyl protein thioesterase 1 (PPT1)." | 1.33 | Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing. ( Ahtiainen, L; Jalanko, A; Kauppi, M; Kopra, O; Luiro, K; Tyynelä, J, 2006) |
| "Late infantile neuronal ceroid lipofuscinosis, LINCL, is one of the most common pediatric neurodegenerative disorders." | 1.30 | Late infantile neuronal ceroid lipofuscinosis is due to splicing mutations in the CLN2 gene. ( Brown, WT; Hartikainen, JM; Ju, W; Kaczmarski, AL; McLendon, L; Moroziewicz, DN; Suarez, CT; Wisniewski, KE; Zhong, D; Zhong, N, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahtiainen, L | 1 |
| Luiro, K | 1 |
| Kauppi, M | 1 |
| Tyynelä, J | 1 |
| Kopra, O | 1 |
| Jalanko, A | 1 |
| Hartikainen, JM | 1 |
| Ju, W | 1 |
| Wisniewski, KE | 1 |
| Moroziewicz, DN | 1 |
| Kaczmarski, AL | 1 |
| McLendon, L | 1 |
| Zhong, D | 1 |
| Suarez, CT | 1 |
| Brown, WT | 1 |
| Zhong, N | 1 |
2 other studies available for adenine and Neuronal Ceroid-Lipofuscinoses
| Article | Year |
|---|---|
Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing.
Topics: Adenine; Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Dextrans; Endocytosis; Fibroblasts; | 2006 |
Late infantile neuronal ceroid lipofuscinosis is due to splicing mutations in the CLN2 gene.
Topics: Adenine; Aminopeptidases; Child; Child, Preschool; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; | 1999 |