Page last updated: 2024-10-16

adenine and Neurofibromatosis 1

adenine has been researched along with Neurofibromatosis 1 in 2 studies

Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).

Research Excerpts

ExcerptRelevanceReference
"The antiretroviral agent tenofovir can cause hypophosphatemic osteomalacia due to renal phosphate wasting."7.77Normal plasma FGF23 levels kinetic in tenofovir-related hypophosphatemic osteomalacia in an HIV-infected patient with von Recklinghausen disease. ( Boissier, MC; Prendki, V; Prie, D; Saidenberg-Kermanac'h, N; Souabni, L, 2011)
"The antiretroviral agent tenofovir can cause hypophosphatemic osteomalacia due to renal phosphate wasting."3.77Normal plasma FGF23 levels kinetic in tenofovir-related hypophosphatemic osteomalacia in an HIV-infected patient with von Recklinghausen disease. ( Boissier, MC; Prendki, V; Prie, D; Saidenberg-Kermanac'h, N; Souabni, L, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saidenberg-Kermanac'h, N1
Souabni, L1
Prendki, V1
Prie, D1
Boissier, MC1
Hatta, N1
Horiuchi, T1
Watanabe, I1
Kobayashi, Y1
Shirakata, Y1
Ohtsuka, H1
Minami, T1
Ueda, K1
Kokoroishi, T1
Fujita, S1

Other Studies

2 other studies available for adenine and Neurofibromatosis 1

ArticleYear
Normal plasma FGF23 levels kinetic in tenofovir-related hypophosphatemic osteomalacia in an HIV-infected patient with von Recklinghausen disease.
    Joint bone spine, 2011, Volume: 78, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Anti-HIV Agents; Drug Substitution; Fibroblast G

2011
NF1 gene mutations in Japanese with neurofibromatosis 1 (NF1).
    Biochemical and biophysical research communications, 1995, Jul-17, Volume: 212, Issue:2

    Topics: Adenine; Adult; Base Sequence; DNA, Complementary; Exons; Female; Guanine; Humans; Introns; Japan; M

1995