Page last updated: 2024-10-16

adenine and Nephritis

adenine has been researched along with Nephritis in 8 studies

Nephritis: Inflammation of any part of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
" In this study, we showed elevated HMGB1 expression in renal granulomas in rats with crystal-induced granulomatous nephritis caused by feeding an adenine-rich diet."7.76High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy. ( Biswas, KK; Hashiguchi, T; Kawahara, K; Lotz, M; Maruyama, I; Nitanda, T; Oyama, Y; Tancharoen, S; Taniguchi, N; Uchimura, T; Umekita, Y, 2010)
"Adenine mice exhibited significantly higher mean serum urea, creatinine, and renal expression of the pro-inflammatory markers Interleukin-6 (IL-6), C-X-C motif chemokine 10 (CXCL10), and Interleukin-1β (IL-1β), in addition to prominent renal fibrosis and reduced renal Klotho gene expression compared to the control."3.88Fish Oil Supplementation Reduces Inflammation but Does Not Restore Renal Function and Klotho Expression in an Adenine-Induced CKD Model. ( Baia, LC; de Borst, MH; Heilberg, IP; Henao Agudelo, JS; Machado, JR; Navis, GJ; Ormanji, MS; Santos, ARP; Saraiva Câmara, NO, 2018)
" Here, we studied whether a specific inhibitor of the Nlrp3 inflammasome, CP-456,773, can prevent kidney fibrosis in a murine model of crystal nephropathy induced by diets rich in oxalate or adenine."3.83An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice. ( Bartok, E; Boor, P; Dhana, E; Evers, BD; Franklin, BS; Hall, JP; Hartmann, G; Hornung, V; Knolle, PA; Kurts, C; Latz, E; Ludwig-Portugall, I; Primiano, MJ, 2016)
" Other types of renal disease frequently encountered during the late period include renal AA-amyloidosis and tenofovir-related kidney disease."3.79[Changing spectrum of renal disease in HIV infection]. ( Amann, K; Bickel, M; Brodt, HR; Geiger, H; Gröne, HJ; Grützmacher, P; Haack, HS; Jung, O, 2013)
" In this study, we showed elevated HMGB1 expression in renal granulomas in rats with crystal-induced granulomatous nephritis caused by feeding an adenine-rich diet."3.76High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy. ( Biswas, KK; Hashiguchi, T; Kawahara, K; Lotz, M; Maruyama, I; Nitanda, T; Oyama, Y; Tancharoen, S; Taniguchi, N; Uchimura, T; Umekita, Y, 2010)
"Hyperuricemia is an independent risk factor for chronic kidney disease (CKD)."1.56Pharmacological inhibition of fatty acid-binding protein 4 alleviated kidney inflammation and fibrosis in hyperuricemic nephropathy. ( Feng, Y; Fu, P; Guo, F; Huang, R; Liao, D; Ma, L; Shi, M; Zeng, X, 2020)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Shi, M1
Guo, F1
Liao, D1
Huang, R1
Feng, Y1
Zeng, X1
Ma, L1
Fu, P1
Wang, B1
Jia, H1
Zhang, B1
Wang, J1
Ji, C1
Zhu, X1
Yan, Y1
Yin, L1
Yu, J1
Qian, H1
Xu, W1
Henao Agudelo, JS1
Baia, LC1
Ormanji, MS1
Santos, ARP1
Machado, JR1
Saraiva Câmara, NO1
Navis, GJ1
de Borst, MH1
Heilberg, IP1
Jung, O1
Haack, HS1
Brodt, HR1
Grützmacher, P1
Geiger, H1
Amann, K1
Gröne, HJ1
Bickel, M1
Aguiar, CF1
Naffah-de-Souza, C1
Castoldi, A1
Corrêa-Costa, M1
Braga, TT1
Naka, ÉL1
Amano, MT1
Abate, DT1
Hiyane, MI1
Cenedeze, MA1
Pacheco e Silva Filho, A1
Câmara, NO1
Ludwig-Portugall, I1
Bartok, E1
Dhana, E1
Evers, BD1
Primiano, MJ1
Hall, JP1
Franklin, BS1
Knolle, PA1
Hornung, V1
Hartmann, G1
Boor, P1
Latz, E1
Kurts, C1
Oyama, Y1
Hashiguchi, T1
Taniguchi, N1
Tancharoen, S1
Uchimura, T1
Biswas, KK1
Kawahara, K1
Nitanda, T1
Umekita, Y1
Lotz, M1
Maruyama, I1
Saito, H1
Kusano, K1
Kinosaki, M1
Ito, H1
Hirata, M1
Segawa, H1
Miyamoto, K1
Fukushima, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Milk Products in the Treatment of Hypophosphatemic Rickets: A Randomised Crossover Trial[NCT03348644]7 participants (Actual)Interventional2015-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

8 other studies available for adenine and Nephritis

ArticleYear
Pharmacological inhibition of fatty acid-binding protein 4 alleviated kidney inflammation and fibrosis in hyperuricemic nephropathy.
    European journal of pharmacology, 2020, Nov-15, Volume: 887

    Topics: Adenine; Animals; Biphenyl Compounds; Cytokines; Fatty Acid-Binding Proteins; Fibrosis; Hepatitis A

2020
Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy.
    Stem cell research & therapy, 2017, 04-08, Volume: 8, Issue:1

    Topics: Adenine; Animals; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Biomarkers; C

2017
Fish Oil Supplementation Reduces Inflammation but Does Not Restore Renal Function and Klotho Expression in an Adenine-Induced CKD Model.
    Nutrients, 2018, Sep-11, Volume: 10, Issue:9

    Topics: Adenine; Animal Feed; Animals; Biomarkers; Dietary Supplements; Disease Models, Animal; Down-Regulat

2018
[Changing spectrum of renal disease in HIV infection].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:38

    Topics: Adenine; Adult; AIDS-Associated Nephropathy; Amyloidosis; Anti-HIV Agents; Antiretroviral Therapy, H

2013
Administration of α-Galactosylceramide Improves Adenine-Induced Renal Injury.
    Molecular medicine (Cambridge, Mass.), 2015, Jun-18, Volume: 21

    Topics: Adenine; Animals; Antigens, CD1d; Collagen Type I; Galactosylceramides; Hepatitis A Virus Cellular R

2015
An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice.
    Kidney international, 2016, Volume: 90, Issue:3

    Topics: Adenine; Adoptive Transfer; Animals; Cells, Cultured; Dendritic Cells; Disease Models, Animal; Fibro

2016
High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy.
    Laboratory investigation; a journal of technical methods and pathology, 2010, Volume: 90, Issue:6

    Topics: Adenine; Animals; Blood Urea Nitrogen; Chemokine CCL2; Creatinine; Epithelial Cells; Granuloma; HMGB

2010
Human fibroblast growth factor-23 mutants suppress Na+-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 production.
    The Journal of biological chemistry, 2003, Jan-24, Volume: 278, Issue:4

    Topics: Adenine; Animals; Biological Transport; Blotting, Western; Cholecalciferol; Cloning, Molecular; COS

2003