adenine has been researched along with Nephritis, Interstitial in 19 studies
Nephritis, Interstitial: Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adenine phosphoribosyltransferase deficiency in mice or an excessive oral intake of adenine leads to the accumulation of 2,8-dihydroxyadenine (DHA) in renal tubules and that causes progressive renal dysfunction accompanied by interstitial fibrosis." | 7.75 | Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model. ( Aizawa, R; Hori, M; Ozaki, H; Tamura, M, 2009) |
| "Acute interstitial nephritis was observed only in 1 of 19 patients without atazanavir or tenofovir treatment." | 5.34 | Acute interstitial nephritis of HIV-positive patients under atazanavir and tenofovir therapy in a retrospective analysis of kidney biopsies. ( Ambuhl, P; Huber, M; Keusch, G; Moch, H; Moddel, M; Opravil, M; Pfammatter, R; Schmid, S; Varga, Z; Wuthrich, RP, 2007) |
| " Here we investigated long-term effects of PHDI treatment in adenine-induced nephropathy as a model for chronic tubulointerstitial nephritis." | 3.91 | Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis. ( Beneke, A; Burzlaff, N; Daniel, C; Eckardt, KU; Goppelt-Struebe, M; Herrmann, M; Jantsch, J; Kalucka, J; Katschinski, DM; Klanke, B; Mayer, M; Palsson, R; Schatz, V; Schley, G; Thorsteinsdottir, M; Weidemann, A; Willam, C, 2019) |
| "The adenine-treated animals exhibited marked azotemia, impaired urinary concentrating capacity, intense tubular and glomerular damage, interstitial inflammation and fibrosis." | 3.79 | Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy. ( Aminzadeh, MA; Nicholas, SB; Norris, KC; Vaziri, ND, 2013) |
| "Adenine overload promotes intratubular crystal precipitation and interstitial nephritis." | 3.79 | NF-κB activation mediates crystal translocation and interstitial inflammation in adenine overload nephropathy. ( Arias, SC; Barlette, GP; Borges, RL; Camara, NO; de Almeida, DC; Fanelli, C; Fujihara, CK; Machado, FG; Malheiros, DM; Okabe, C; Zatz, R, 2013) |
| "Adenine phosphoribosyltransferase deficiency in mice or an excessive oral intake of adenine leads to the accumulation of 2,8-dihydroxyadenine (DHA) in renal tubules and that causes progressive renal dysfunction accompanied by interstitial fibrosis." | 3.75 | Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model. ( Aizawa, R; Hori, M; Ozaki, H; Tamura, M, 2009) |
| "Acute interstitial nephritis was observed only in 1 of 19 patients without atazanavir or tenofovir treatment." | 1.34 | Acute interstitial nephritis of HIV-positive patients under atazanavir and tenofovir therapy in a retrospective analysis of kidney biopsies. ( Ambuhl, P; Huber, M; Keusch, G; Moch, H; Moddel, M; Opravil, M; Pfammatter, R; Schmid, S; Varga, Z; Wuthrich, RP, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 13 (68.42) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, H | 1 |
| Zheng, C | 1 |
| Zhu, L | 1 |
| Song, Z | 1 |
| Dai, L | 1 |
| Hu, Q | 1 |
| Wang, L | 1 |
| Chen, Y | 1 |
| Xiong, J | 1 |
| Markóth, C | 1 |
| File, I | 1 |
| Szász, R | 1 |
| Bidiga, L | 1 |
| Balla, J | 1 |
| Mátyus, J | 1 |
| Schley, G | 1 |
| Klanke, B | 1 |
| Kalucka, J | 1 |
| Schatz, V | 1 |
| Daniel, C | 1 |
| Mayer, M | 1 |
| Goppelt-Struebe, M | 1 |
| Herrmann, M | 1 |
| Thorsteinsdottir, M | 1 |
| Palsson, R | 1 |
| Beneke, A | 1 |
| Katschinski, DM | 1 |
| Burzlaff, N | 1 |
| Eckardt, KU | 1 |
| Weidemann, A | 1 |
| Jantsch, J | 1 |
| Willam, C | 1 |
| Aminzadeh, MA | 1 |
| Nicholas, SB | 1 |
| Norris, KC | 1 |
| Vaziri, ND | 2 |
| Okabe, C | 1 |
| Borges, RL | 1 |
| de Almeida, DC | 1 |
| Fanelli, C | 1 |
| Barlette, GP | 1 |
| Machado, FG | 1 |
| Arias, SC | 1 |
| Malheiros, DM | 1 |
| Camara, NO | 3 |
| Zatz, R | 2 |
| Fujihara, CK | 1 |
| Jia, T | 1 |
| Olauson, H | 1 |
| Lindberg, K | 1 |
| Amin, R | 1 |
| Edvardsson, K | 1 |
| Lindholm, B | 1 |
| Andersson, G | 1 |
| Wernerson, A | 1 |
| Sabbagh, Y | 1 |
| Schiavi, S | 1 |
| Larsson, TE | 1 |
| Hamasaki, Y | 1 |
| Doi, K | 1 |
| Maeda-Mamiya, R | 1 |
| Ogasawara, E | 1 |
| Katagiri, D | 1 |
| Tanaka, T | 1 |
| Yamamoto, T | 1 |
| Sugaya, T | 1 |
| Nangaku, M | 1 |
| Noiri, E | 1 |
| Correa-Costa, M | 2 |
| Braga, TT | 2 |
| Felizardo, RJ | 1 |
| Andrade-Oliveira, V | 1 |
| Perez, KR | 1 |
| Cuccovia, IM | 1 |
| Hiyane, MI | 1 |
| da Silva, JS | 1 |
| Hussein, AM | 1 |
| Malek, HA | 1 |
| Saad, MA | 1 |
| Chen, H | 1 |
| Cao, G | 1 |
| Chen, DQ | 1 |
| Wang, M | 1 |
| Zhang, ZH | 1 |
| Mao, JR | 1 |
| Bai, X | 1 |
| Zhao, YY | 1 |
| Tamura, M | 1 |
| Aizawa, R | 1 |
| Hori, M | 1 |
| Ozaki, H | 1 |
| Shpacovitch, V | 1 |
| Mertens, PR | 1 |
| Nozue, H | 1 |
| Kamoda, T | 1 |
| Saitoh, H | 1 |
| Ichikawa, K | 1 |
| Taniguchi, A | 1 |
| Semedo, P | 1 |
| Hayashida, CY | 1 |
| Bechara, LR | 1 |
| Elias, RM | 1 |
| Barreto, CR | 1 |
| Silva-Cunha, C | 1 |
| Hyane, MI | 1 |
| Gonçalves, GM | 1 |
| Brum, PC | 1 |
| Fujihara, C | 1 |
| Pacheco-Silva, A | 1 |
| Zamboni, DS | 1 |
| Dai, CL | 1 |
| Zhu, M | 1 |
| Wang, BP | 1 |
| Guo, F | 1 |
| Zhang, X | 1 |
| Song, WZ | 1 |
| Zhu, TH | 1 |
| Wang, BL | 1 |
| Qiu, MC | 1 |
| Nishijima, T | 1 |
| Yazaki, H | 1 |
| Hinoshita, F | 1 |
| Tasato, D | 1 |
| Hoshimoto, K | 1 |
| Teruya, K | 1 |
| Gatanaga, H | 1 |
| Kikuchi, Y | 1 |
| Oka, S | 1 |
| Schmid, S | 1 |
| Opravil, M | 1 |
| Moddel, M | 1 |
| Huber, M | 1 |
| Pfammatter, R | 1 |
| Keusch, G | 1 |
| Ambuhl, P | 1 |
| Wuthrich, RP | 1 |
| Moch, H | 1 |
| Varga, Z | 1 |
| Fine, DM | 1 |
| Perazella, MA | 1 |
| Lucas, GM | 1 |
| Atta, MG | 1 |
| Brown, HA | 1 |
1 review available for adenine and Nephritis, Interstitial
| Article | Year |
|---|---|
Kidney biopsy in HIV: beyond HIV-associated nephropathy.
Topics: Acute Disease; Adenine; AIDS-Associated Nephropathy; Anti-HIV Agents; Antiretroviral Therapy, Highly | 2008 |
18 other studies available for adenine and Nephritis, Interstitial
| Article | Year |
|---|---|
Contribution of TFEB-mediated autophagy to tubulointerstitial fibrosis in mice with adenine-induced chronic kidney disease.
Topics: Adenine; Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line; | 2021 |
Ibrutinib-induced acute kidney injury via interstitial nephritis.
Topics: Acute Kidney Injury; Adenine; Aged; Cytokines; Glucocorticoids; Humans; Kidney; Leukemia, Prolymphoc | 2021 |
Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis.
Topics: Adenine; Animals; Anti-Inflammatory Agents; Basic Helix-Loop-Helix Transcription Factors; Clodronic | 2019 |
Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy.
Topics: Adenine; Animals; Arachidonate 12-Lipoxygenase; Blotting, Western; Catalase; Chronic Disease; Cycloo | 2013 |
NF-κB activation mediates crystal translocation and interstitial inflammation in adenine overload nephropathy.
Topics: Adenine; Animals; Disease Models, Animal; Fibrosis; Granuloma; Inflammation Mediators; Kidney; Male; | 2013 |
A novel model of adenine-induced tubulointerstitial nephropathy in mice.
Topics: Adenine; Animals; Disease Models, Animal; Fibroblast Growth Factor-23; Mice; Mice, Inbred C57BL; Nep | 2013 |
A 5-hydroxytryptamine receptor antagonist, sarpogrelate, reduces renal tubulointerstitial fibrosis by suppressing PAI-1.
Topics: Adenine; Animals; Cells, Cultured; Disease Models, Animal; Fatty Acid-Binding Proteins; Fibrosis; In | 2013 |
Macrophage trafficking as key mediator of adenine-induced kidney injury.
Topics: Acute Kidney Injury; Adenine; Animals; Chemokine CCL3; Flow Cytometry; Kidney; Macrophages; Mice; Mi | 2014 |
Renoprotective effects of aliskiren on adenine-induced tubulointerstitial nephropathy: possible underlying mechanisms.
Topics: Adenine; Amides; Animals; Apoptosis; Fumarates; Male; Nephritis, Interstitial; Protective Agents; Ra | 2016 |
Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression.
Topics: Adenine; Animals; Aristolochic Acids; Biomarkers; Disease Models, Animal; Disease Progression; Early | 2016 |
Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model.
Topics: Actins; Adenine; Animals; Chemokines; Chemotaxis; Collagen; Cytokines; Disease Models, Animal; Fibro | 2009 |
High mobility group box protein-1 crossing cell borders may incite an inflammatory "tornado" in renal disease.
Topics: Adenine; Animals; Chemokine CCL2; Disease Progression; HMGB1 Protein; Kidney; Macrophages; Mice; Nep | 2010 |
A Japanese boy with adenine phosphoribosyltransferase (APRT) deficiency caused by compound heterozygosity including a novel missense mutation in APRT gene.
Topics: Adenine; Adenine Phosphoribosyltransferase; Asian People; Child, Preschool; Humans; Lithotripsy; Mal | 2011 |
Pivotal role of Toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflammasome complex in experimental tubule-interstitial nephritis.
Topics: Adenine; Allopurinol; Animals; Diet; Disease Progression; Inflammasomes; Inflammation; Kidney Tubule | 2011 |
Prolonged adefovir therapy associated Fanconi syndrome and interstitial nephritis in hepatitis B.
Topics: Adenine; Drug Administration Schedule; Fanconi Syndrome; Hepatitis B; Humans; Male; Middle Aged; Nep | 2012 |
Drug-induced acute interstitial nephritis mimicking acute tubular necrosis after initiation of tenofovir-containing antiretroviral therapy in patient with HIV-1 infection.
Topics: Acute Disease; Adenine; Aged; Anti-Retroviral Agents; Biopsy; Diagnosis, Differential; HIV Infection | 2012 |
Acute interstitial nephritis of HIV-positive patients under atazanavir and tenofovir therapy in a retrospective analysis of kidney biopsies.
Topics: Acute Kidney Injury; Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; Female; Fluorescent Antibo | 2007 |
Recurrence of 2,8-dihydroxyadenine tubulointerstitial lesions in a kidney transplant recipient with a primary presentation of chronic renal failure.
Topics: Adenine; Adenine Phosphoribosyltransferase; Female; Humans; Kidney Failure, Chronic; Kidney Transpla | 1998 |