adenine has been researched along with Neoplasms in 167 studies
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The therapeutic potential of the antiretroviral drug 9-(2-phosphonylmethoxyethyl)adenine (PMEA, adefovir) for the treatment of human immunodeficiency virus (HIV)- and human hepatitis B virus (HBV) infections is currently being explored in advanced clinical trials." | 3.70 | Mechanistic study on the cytostatic and tumor cell differentiation-inducing properties of 9-(2-phosphonylmethoxyethyl)adenine (PMEA, adefovir)-collected publications. ( Hatse, S, 2000) |
| " A traditional 3 + 3 dose escalation design with 5 dosing cohorts was used." | 3.11 | Phase I dose escalation study of dual PI3K/mTOR inhibition by Sapanisertib and Serabelisib in combination with paclitaxel in patients with advanced solid tumors. ( Meissner, T; Rojas-Espaillat, L; Starks, DC; Williams, CB, 2022) |
| " In addition to determining the MTD, we evaluated pharmacokinetics of BIIB021 and pharmacodynamic effects of BIIB021 [Hsp70, HER2 extracellular domain (HER2-ECD)]." | 2.79 | A phase 1, dose-escalation, pharmacokinetic and pharmacodynamic study of BIIB021 administered orally in patients with advanced solid tumors. ( Banerji, U; Castro, J; Lamanna, N; Mita, M; O'Brien, S; Saif, MW; Stogard, C; Takimoto, C; Von Hoff, D, 2014) |
| "These cancers are potential targets for selective chemotherapy with inhibitors of de novo adenine synthesis such as L-alanosine [L-2-amino-3-(N-hydroxy-N-nitrosamino) propionic acid]." | 2.74 | A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer. ( Burris, HA; Kindler, HL; Oliff, IA; Sandler, AB, 2009) |
| "The outbreak of the novel coronavirus disease 2019 (COVID-19) has emerged as one of the biggest global health threats worldwide." | 2.72 | Relevance of the Bruton Tyrosine Kinase as a Target for COVID-19 Therapy. ( Macip, S; Massip-Salcedo, M; Qusairy, Z; Rada, M, 2021) |
| " Furthermore, the nanoformulations studied to increase ibrutinib bioavailability are reported." | 2.72 | Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective. ( Brullo, C; Russo, E; Spallarossa, A; Tasso, B; Villa, C, 2021) |
| "Amonafide (A) demonstrates dose-related increases in area under the curve (AUC) and Cmax values." | 2.68 | Clinical pharmacokinetics of amonafide (NSC 308847) in 62 patients. ( Akerman, S; Allen, SL; Budman, DR; Calabro, A; Chan, K; Fusco, D; Hock, K; Kreis, W; Mittelman, A; Puccio, C; Spigelman, M, 1996) |
| "Twenty-six patients with advanced cancer underwent acetylator phenotyping with caffeine and were assigned to a dose level." | 2.67 | Phase I study of amonafide dosing based on acetylator phenotype. ( Berezin, F; Janisch, L; Lane, LB; Mick, R; Ratain, MJ; Schilsky, RL; Vogelzang, NJ, 1993) |
| "EMT is involved in tumor metastasis because it leads to cancer cell migration and invasion, and is also associated with chemoresistance." | 2.66 | Regulation of Epithelial-to-Mesenchymal Transition by Alternative Translation Initiation Mechanisms and Its Implications for Cancer Metastasis. ( Bera, A; Lewis, SM, 2020) |
| "Cell purine metabolism is an important drug target." | 2.61 | Purine auxotrophy: Possible applications beyond genetic marker. ( Kokina, A; Liepins, J; Ozolina, Z, 2019) |
| "However, in the stratified analysis of cancer type, the significant results were only found in lung cancer (dominant model: OR = 0." | 2.55 | Association between MPO-463G > A polymorphism and cancer risk: evidence from 60 case-control studies. ( Cen, H; Pan, FZ; Shi, C; Wang, MY; Yang, WJ, 2017) |
| "Hsp90 allows cancer cells to tolerate the many components of dysregulated pathways in a transformation-specific manner by interacting with several client substrates, such as kinases, hormone receptors and transcription factors that are directly involved in driving multistep malignancy, and also with mutated oncogenic proteins required for the transformed phenotype." | 2.43 | Discovery and development of purine-scaffold Hsp90 inhibitors. ( Chiosis, G, 2006) |
| "HBsAg-positive cancer patients treated with ETV (n = 582), TDF (n = 200) and TAF (n = 188) during chemotherapy were retrospectively enrolled." | 1.72 | Efficacy and Renal Safety of Prophylactic Tenofovir Alafenamide for HBV-Infected Cancer Patients Undergoing Chemotherapy. ( Chao, Y; Hou, MC; Huang, YH; Lan, KH; Lee, IC; Li, CP; Lin, HC; Su, CW, 2022) |
| "The B-cell neoplasm could not be further subclassified due to the lack of BCL2-IgH and BCL1-IgH rearrangement and morphology." | 1.62 | [Small B-cell neoplasm responding to ibrutinib after 17 years of cold agglutinin disease symptom]. ( Haga, H; Hishizawa, M; Hori, T; Iga, Y; Kondo, T; Masuda, K; Morimoto, S; Morita, M; Shindo, T; Takaori-Kondo, A; Yamashita, K; Yurugi, K, 2021) |
| " This study assessed the in vitro and in vivo functionality of CAR T cells transduced to express the anti-CD19 CAR of liso-cel in combination with ibrutinib or acalabrutinib." | 1.56 | Antitumor Potency of an Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, Lisocabtagene Maraleucel in Combination With Ibrutinib or Acalabrutinib. ( Baturevych, A; Clouser, CR; Hause, RJ; Johnstone, TG; Jones, JC; Krejsa, CM; Ponce, R; Ports, MO; Qin, JS; Ragan, SP; Salmon, RA, 2020) |
| " In addition, CQ, Ku, and Rap in combination with RL2 decreased activity of lysosomal protease Cathepsin D." | 1.51 | Cytotoxic and Antitumor Activity of Lactaptin in Combination with Autophagy Inducers and Inhibitors. ( Bagamanshina, AV; Kähne, T; Kit, YY; Koval, OA; Kuligina, EV; Lavrik, IN; Nushtaeva, AA; Richter, M; Richter, VA; Starykovych, MO; Troitskaya, OS; Wohlfromm, F; Yunusova, AY, 2019) |
| "We found that poor breast cancer patient survival was significantly associated with low TTP/HuR mRNA ratios and correlated with high levels of the mitotic ARE-mRNA signature." | 1.43 | Systematic Analysis of AU-Rich Element Expression in Cancer Reveals Common Functional Clusters Regulated by Key RNA-Binding Proteins. ( Al-Ghamdi, M; Al-Saif, M; Al-Souhibani, N; Al-Yahya, S; Bakheet, T; Grépin, R; Győrffy, B; Hitti, E; Khabar, KS; Lánczky, A; Moghrabi, W; Pagès, G; Shoukri, MM, 2016) |
| "Numerous cancer types exhibit high inter- and intratumor heterogeneity of H1." | 1.43 | The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity. ( Ben-Hamo, R; Biran, A; Burney, MJ; Chakravarty, P; Cohen, AS; Efroni, S; Henser-Brownhill, T; Li, Y; Matthews, N; Meshorer, E; Misteli, T; Nye, E; Patel, H; Scaffidi, P; Spencer-Dene, B; Torres, CM, 2016) |
| "This cleansing function is required for cancer cell survival and to modulate Escherichia coli antibiotic sensitivity in a DNA polymerase (pol)-dependent manner." | 1.42 | Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. ( Beard, WA; Freudenthal, BD; Kim, T; Perera, L; Schlick, T; Shock, DD; Wilson, SH, 2015) |
| "This study aims to evaluate the anti-cancer effect of daucosterol and explore its possible mechanism." | 1.42 | Daucosterol inhibits cancer cell proliferation by inducing autophagy through reactive oxygen species-dependent manner. ( Cai, S; Gao, Y; Qu, L; She, T; Shou, C; Su, Y; Wang, L; Xu, S; Zhao, C, 2015) |
| "Concentrations achieved in vivo in tumors lead to single-agent anti-tumor activity at non-toxic doses." | 1.32 | Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90. ( Basso, A; Chiosis, G; He, H; Huezo, H; Lucas, B; Modrich, P; Rosen, N; Solit, D; Spampinato, C; Vilenchik, M, 2004) |
| "Kinetin riboside was shown to only act on M4 Beu human and B16 murine melanoma cells at low concentration (1." | 1.32 | Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells. ( Bos, R; Griffaut, B; Ledoigt, G; Madelmont, JC; Maurizis, JC, 2004) |
| "The azonafides are a series of anthracene-based DNA intercalators which inhibit tumor cell growth in vitro at low nanomolar concentrations and are not affected by the multidrug resistance phenomenon (MDR)." | 1.31 | Preclinical antitumor activity of the azonafide series of anthracene-based DNA intercalators. ( Alberts, DS; Dorr, RT; Hersh, EM; Liddil, JD; Remers, W; Sami, SM, 2001) |
| "The effects of cancer procoagulant (CP), cysteine protease (EC 3." | 1.31 | Cancer procoagulant and blood platelet activation. ( Mielicki, WP; Olas, B; Wachowicz, B, 2001) |
| "All patients had a family history of tumors previously associated with A-T heterozygosity or homozygosity." | 1.29 | ATM mutations in cancer families. ( Croce, CM; Hammarström, L; Lindblom, A; Luo, L; Negrini, M; Vorechovský, I; Webster, AD, 1996) |
| " The drug was found to be toxic to all of the cell lines tested." | 1.27 | Studies on the mechanism of cytotoxicity of 3-deazaguanosine in human cancer cells. ( Jacobsen, SJ; Mangum, JH; Nyhan, WL; Page, T; Robins, RK; Scheele, J; Smejkal, RM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 52 (31.14) | 18.7374 |
| 1990's | 6 (3.59) | 18.2507 |
| 2000's | 25 (14.97) | 29.6817 |
| 2010's | 58 (34.73) | 24.3611 |
| 2020's | 26 (15.57) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 3 |
| Hitosugi, T | 1 |
| Zhang, L | 4 |
| Zhang, S | 3 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 2 |
| Li, Y | 6 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 3 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 3 |
| Kang, S | 2 |
| Fan, J | 1 |
| Chen, J | 4 |
| Wu, F | 2 |
| Liu, Y | 11 |
| Cheng, H | 2 |
| Meng, Y | 1 |
| Shi, J | 3 |
| Chen, Y | 2 |
| Wu, Y | 3 |
| Ran, F | 1 |
| Wang, C | 4 |
| Xu, Z | 1 |
| Zhang, Y | 9 |
| Zhao, G | 1 |
| Ling, Y | 1 |
| Morimoto, S | 1 |
| Shindo, T | 1 |
| Iga, Y | 1 |
| Morita, M | 1 |
| Yurugi, K | 1 |
| Masuda, K | 1 |
| Hori, T | 1 |
| Hishizawa, M | 1 |
| Kondo, T | 1 |
| Yamashita, K | 1 |
| Haga, H | 1 |
| Takaori-Kondo, A | 1 |
| Guan, Q | 1 |
| Lin, H | 1 |
| Miao, L | 1 |
| Guo, H | 2 |
| Zhuo, Z | 1 |
| He, J | 1 |
| Starks, DC | 1 |
| Rojas-Espaillat, L | 1 |
| Meissner, T | 1 |
| Williams, CB | 1 |
| Dogan, S | 1 |
| Spahiu, E | 1 |
| Cilic, A | 1 |
| Lee, IC | 1 |
| Lan, KH | 1 |
| Su, CW | 1 |
| Li, CP | 1 |
| Chao, Y | 1 |
| Lin, HC | 1 |
| Hou, MC | 1 |
| Huang, YH | 1 |
| Liu, X | 5 |
| Chen, W | 2 |
| Xu, Y | 2 |
| Shen, Y | 2 |
| Xu, X | 2 |
| Kozmin, SG | 1 |
| Rogozin, IB | 1 |
| Moore, EA | 1 |
| Abney, M | 1 |
| Schaaper, RM | 1 |
| Pavlov, YI | 1 |
| Shi, X | 3 |
| Zhang, D | 1 |
| Li, F | 1 |
| Zhang, Z | 3 |
| Wang, S | 1 |
| Xuan, Y | 1 |
| Ping, Y | 1 |
| Li, K | 1 |
| Lu, L | 1 |
| Xue, C | 1 |
| Liu, J | 6 |
| He, Y | 3 |
| Zhou, J | 2 |
| Xia, Z | 1 |
| Dai, L | 1 |
| Luo, Z | 1 |
| Mao, Y | 1 |
| Cai, K | 1 |
| Qin, JS | 1 |
| Johnstone, TG | 1 |
| Baturevych, A | 1 |
| Hause, RJ | 1 |
| Ragan, SP | 1 |
| Clouser, CR | 1 |
| Jones, JC | 1 |
| Ponce, R | 1 |
| Krejsa, CM | 1 |
| Salmon, RA | 1 |
| Ports, MO | 1 |
| García-Raso, A | 1 |
| Terrón, A | 1 |
| Ortega-Castro, J | 1 |
| Barceló-Oliver, M | 1 |
| Lorenzo, J | 1 |
| Rodríguez-Calado, S | 1 |
| Franconetti, A | 1 |
| Frontera, A | 1 |
| Vázquez-López, EM | 1 |
| Fiol, JJ | 1 |
| Krause, G | 1 |
| Hassenrück, F | 1 |
| Hallek, M | 1 |
| Saini, N | 1 |
| Sterling, JF | 1 |
| Sakofsky, CJ | 1 |
| Giacobone, CK | 1 |
| Klimczak, LJ | 1 |
| Burkholder, AB | 1 |
| Malc, EP | 1 |
| Mieczkowski, PA | 1 |
| Gordenin, DA | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhao, Y | 3 |
| Wang, J | 7 |
| Huang, L | 3 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 4 |
| Guo, Z | 1 |
| Song, Y | 2 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 5 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 4 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 2 |
| Sun, M | 2 |
| Xu, G | 1 |
| Zhang, X | 7 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 2 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 2 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 2 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Hu, Z | 2 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 10 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 2 |
| Huang, X | 2 |
| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 7 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Song, J | 2 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Zhang, H | 3 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 1 Evaluation of the Safety and Tolerability of TAK-228 in Combination With TAK-117 and Paclitaxel in Advanced Solid Tumors[NCT03154294] | Phase 1 | 30 participants (Anticipated) | Interventional | 2017-07-06 | Active, not recruiting | ||
| A Phase 1, Multicenter, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of BIIB021 Administered Once or Twice Daily to Subjects With Advanced Solid Tumors[NCT00618735] | Phase 1 | 68 participants (Actual) | Interventional | 2008-02-29 | Completed | ||
| An Open-Label, Multicenter, Pharmacokinetic Study of PCI-32765 in Subjects With Varying Degrees of Hepatic Impairment[NCT01767948] | Phase 1 | 30 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| Phase I Dose-escalation, Pharmacokinetic and Pharmacodynamic Study of Debio 0932, a Novel Hsp90-inhibitor, Administered Orally, in Patients With Advanced Solid Tumours or Lymphoma[NCT01168752] | Phase 1 | 81 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
29 reviews available for adenine and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Review of the development of BTK inhibitors in overcoming the clinical limitations of ibrutinib.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; B-Lymphocytes; Cyclin-Dependent Kinase 4; Drug Resista | 2022 |
Functions, mechanisms, and therapeutic implications of METTL14 in human cancer.
Topics: Adenine; Animals; Carcinogenesis; Gene Expression Regulation, Neoplastic; Humans; Methylation; Methy | 2022 |
Targeting IGF2BP3 in Cancer.
Topics: Adenine; Adenosine; Eukaryota; Humans; Neoplasms; RNA | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Regulation of Epithelial-to-Mesenchymal Transition by Alternative Translation Initiation Mechanisms and Its Implications for Cancer Metastasis.
Topics: Adenine; Animals; Disease Progression; Epithelial-Mesenchymal Transition; Humans; Models, Biological | 2020 |
Principles of RNA methylation and their implications for biology and medicine.
Topics: Adenine; AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Hu | 2020 |
Relevance of the Bruton Tyrosine Kinase as a Target for COVID-19 Therapy.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Antiviral Agents; Benzamides; COVID-19; COVID-19 Drug | 2021 |
Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Chemistry, Pharmaceutical; COVID-19 Drug Treatment; Dr | 2021 |
BIIB021: A novel inhibitor to heat shock protein 90-addicted oncology.
Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; HSP90 Heat-Shock Proteins; Humans; Mice; Neoplas | 2017 |
Bruton's tyrosine kinase (BTK) as a promising target in solid tumors.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Humans; Neoplasms; Pip | 2017 |
Association between MPO-463G > A polymorphism and cancer risk: evidence from 60 case-control studies.
Topics: Adenine; Asian People; Gene Frequency; Genetic Predisposition to Disease; Genotype; Guanine; Humans; | 2017 |
N(6)-Methyladenine in eukaryotes.
Topics: Adenine; Animals; DNA Methylation; DNA Repair Enzymes; Epigenomics; Eukaryota; Humans; Neoplasms; Ox | 2019 |
Purine auxotrophy: Possible applications beyond genetic marker.
Topics: Adenine; Cell Cycle Checkpoints; Drug Development; Eukaryota; Humans; Neoplasms; Purines; Saccharomy | 2019 |
Bruton's TK inhibitors: structural insights and evolution of clinical candidates.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Autoimmune Diseases; Clinical Trials as Topic | 2014 |
Ibrutinib: a first in class covalent inhibitor of Bruton's tyrosine kinase.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; Antineoplastic Combine | 2014 |
Ibrutinib-A double-edge sword in cancer and autoimmune disorders.
Topics: Adenine; Animals; Autoimmune Diseases; Humans; Immunologic Factors; Neoplasms; Piperidines; Protein- | 2016 |
Small molecule inhibitors of the PI3-kinase family.
Topics: Adenine; Androstadienes; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Chrom | 2010 |
[Progress in the study of heat shock protein 90 inhibitors].
Topics: Adenine; Animals; Anisoles; Antineoplastic Agents; Benzoquinones; Catechin; Cell Line, Tumor; Crysta | 2010 |
Molecular crosstalk between the proteasome, aggresomes and autophagy: translational potential and clinical implications.
Topics: Adenine; Antineoplastic Agents; Autophagy; Boronic Acids; Bortezomib; Chloroquine; Clinical Trials a | 2012 |
HSP90 inhibitors: current development and potential in cancer therapy.
Topics: Adenine; Animals; Antineoplastic Agents; Benzodioxoles; Cell Membrane; Clinical Trials as Topic; Dru | 2014 |
AT islands - their nature and potential for anticancer strategies.
Topics: Adenine; Animals; Antineoplastic Agents; DNA Replication; DNA, Neoplasm; Drug Evaluation, Preclinica | 2004 |
Methylthioadenosine.
Topics: Adenine; Animals; Apoptosis; Cell Differentiation; Deoxyadenosines; Gene Expression Regulation; Huma | 2004 |
Discovery and development of purine-scaffold Hsp90 inhibitors.
Topics: Adenine; Animals; Anisoles; Antineoplastic Agents; Drug Design; HSP90 Heat-Shock Proteins; Humans; M | 2006 |
Adenine-N3 in the DNA minor groove - an emerging target for platinum containing anticancer pharmacophores.
Topics: Acridines; Adenine; Animals; Antineoplastic Agents; DNA Adducts; Humans; Models, Molecular; Molecula | 2007 |
Lipid peroxidation-induced DNA damage in cancer-prone inflammatory diseases: a review of published adduct types and levels in humans.
Topics: Adenine; Animals; Biomarkers; Deoxyadenosines; Deoxyguanosine; DNA Adducts; DNA Damage; Humans; Infl | 2007 |
Novel chemotherapeutic agents in early clinical development.
Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; | 1990 |
Exposure of humans to endogenous N-nitroso compounds: implications in cancer etiology.
Topics: Adenine; Bacterial Infections; Esophageal Neoplasms; Gastric Mucosa; Humans; Kinetics; Methylation; | 1990 |
Notes on some peculiarities of enzymic processes in malignant tumours and tissues of the host.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cholesterol; DNA, Neoplasm; | 1972 |
10 trials available for adenine and Neoplasms
| Article | Year |
|---|---|
Phase I dose escalation study of dual PI3K/mTOR inhibition by Sapanisertib and Serabelisib in combination with paclitaxel in patients with advanced solid tumors.
Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Benzoxazoles; Cohort Studies; Humans; Imida | 2022 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
A Phase 1b/2 Study of the Bruton Tyrosine Kinase Inhibitor Ibrutinib and the PD-L1 Inhibitor Durvalumab in Patients with Pretreated Solid Tumors.
Topics: Adenine; Adult; Agammaglobulinaemia Tyrosine Kinase; Aged; Aged, 80 and over; Antibodies, Monoclonal | 2019 |
A phase 1, dose-escalation, pharmacokinetic and pharmacodynamic study of BIIB021 administered orally in patients with advanced solid tumors.
Topics: Adenine; Administration, Oral; Antineoplastic Agents; Biopsy; Drug Administration Schedule; Fluorode | 2014 |
Preemptive adefovir versus lamivudine for prevention of hepatitis B reactivation in chronic hepatitis B patients undergoing chemotherapy.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Femal | 2015 |
Single-dose pharmacokinetics of ibrutinib in subjects with varying degrees of hepatic impairment.
Topics: Adenine; Adult; Aged; Area Under Curve; Biomarkers; Drug Monitoring; Female; Humans; Incidence; Live | 2017 |
A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer.
Topics: Adenine; Adolescent; Adult; Aged; Alanine; Antimetabolites, Antineoplastic; Drug Administration Sche | 2009 |
Phase I study of amonafide dosing based on acetylator phenotype.
Topics: Acetylation; Adenine; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; | 1993 |
Clinical pharmacokinetics of amonafide (NSC 308847) in 62 patients.
Topics: Adenine; Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Half-Life; Hu | 1996 |
Novel chemotherapeutic agents in early clinical development.
Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; | 1990 |
130 other studies available for adenine and Neoplasms
| Article | Year |
|---|---|
Enhanced Cancer Starvation Therapy Based on Glucose Oxidase/3-Methyladenine-Loaded Dendritic Mesoporous OrganoSilicon Nanoparticles.
Topics: Adenine; Animals; Cell Line, Tumor; Cell Proliferation; Dendrimers; Female; Glucose Oxidase; Humans; | 2021 |
[Small B-cell neoplasm responding to ibrutinib after 17 years of cold agglutinin disease symptom].
Topics: Adenine; Aged; Anemia, Hemolytic, Autoimmune; Female; Humans; Lymphoproliferative Disorders; Neoplas | 2021 |
Structural Analysis of microRNAs in Myeloid Cancer Reveals Consensus Motifs.
Topics: Adenine; Base Sequence; MicroRNAs; Neoplasms; Nucleotides; Uracil | 2022 |
Tam CS, Dimopoulos M, Garcia-Sanz R, et al. Pooled safety analysis of zanubrutinib monotherapy in patients with B-cell malignancies. Blood Adv. 2022;6(4):1296-1308.
Topics: Adenine; Humans; Neoplasms; Piperidines; Pyrazoles; Pyrimidines | 2022 |
Efficacy and Renal Safety of Prophylactic Tenofovir Alafenamide for HBV-Infected Cancer Patients Undergoing Chemotherapy.
Topics: Acute Kidney Injury; Adenine; Alanine; Antiviral Agents; Cisplatin; Hepatitis B Surface Antigens; He | 2022 |
Comment on "A commensal strain of
Topics: Adenine; Humans; Mutagenesis; Neoplasms; Saccharomyces cerevisiae; Staphylococcus epidermidis | 2019 |
Targeting glycosylation of PD-1 to enhance CAR-T cell cytotoxicity.
Topics: Adenine; Animals; Cytotoxicity, Immunologic; Glycosylation; Humans; Immunotherapy, Adoptive; Lymphoc | 2019 |
Polarization of tumor-associated macrophage phenotype via porous hollow iron nanoparticles for tumor immunotherapy in vivo.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Drug Carriers; Female; Ferrosofer | 2020 |
Antitumor Potency of an Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, Lisocabtagene Maraleucel in Combination With Ibrutinib or Acalabrutinib.
Topics: Adenine; Animals; Antigens, CD19; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomar | 2020 |
Iridium(III) coordination of N(6) modified adenine derivatives with aminoacid chains.
Topics: A549 Cells; Adenine; Antineoplastic Agents; Coordination Complexes; HeLa Cells; Humans; Iridium; MCF | 2020 |
Cell line-based assessment of BTK inhibitors.
Topics: Adenine; B-Lymphocytes; Cell Line; Humans; Mutation; Neoplasms; Piperidines; Protein Kinase Inhibito | 2020 |
Mutation signatures specific to DNA alkylating agents in yeast and cancers.
Topics: Adenine; Alkylating Agents; Animals; DNA Glycosylases; DNA, Fungal; DNA, Single-Stranded; Humans; Mi | 2020 |
Self-assembled nucleo-tripeptide hydrogels provide local and sustained doxorubicin release.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; | 2020 |
Ibrutinib Is a Newly Recognized Host Factor for the Definition of Probable Invasive Pulmonary Mold Disease, Based on Off-target Effects, Unrelated to Its B-cell Immunosuppressant Activity.
Topics: Adenine; B-Lymphocytes; Consensus; Humans; Immunosuppressive Agents; Mycoses; Neoplasms; Piperidines | 2020 |
Improved time to treatment failure and survival in ibrutinib-treated malignancies with a pharmaceutical care program: an observational cohort study.
Topics: Adenine; Aged; Aged, 80 and over; Cohort Studies; Efficiency, Organizational; Female; Humans; Male; | 2020 |
Cutaneous adverse-events in patients treated with Ibrutinib.
Topics: Adenine; Humans; Neoplasms; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines | 2020 |
Pyogenic Granuloma During Ibrutinib Therapy for B-Cell Neoplasia.
Topics: Adenine; B-Lymphocytes; Granuloma, Pyogenic; Humans; Neoplasms; Piperidines; Pyrazoles | 2020 |
Adenine-Functionalized Supramolecular Micelles for Selective Cancer Chemotherapy.
Topics: Adenine; Antineoplastic Agents; Cell Line, Tumor; Delayed-Action Preparations; Doxorubicin; Drug Car | 2020 |
Cardio-Oncology: A Win-Win Situation: How Solving the Mystery of an Ibrutinib Off-Target Effect Reveals New Insights Into Atrial Fibrillation Mechanisms.
Topics: Adenine; Atrial Fibrillation; Humans; Neoplasms; Piperidines; Pyrazoles; Pyrimidines | 2020 |
The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51.
Topics: Adenine; Animals; Autophagy; Beclin-1; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; En | 2021 |
Solid-State Nanopore Analysis of Diverse DNA Base Modifications Using a Modular Enzymatic Labeling Process.
Topics: Adenine; Base Pair Mismatch; Biosensing Techniques; DNA; DNA Damage; DNA Repair; Epigenesis, Genetic | 2017 |
Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner.
Topics: A549 Cells; Adenine; Animals; Cell Proliferation; Cells, Cultured; Humans; Mice; Mice, Inbred NOD; M | 2018 |
Resveratrol induces autophagy-dependent apoptosis in HL-60 cells.
Topics: Adenine; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Antineoplastic Agents, | 2018 |
Drug-Controlled Release Based on Complementary Base Pairing Rules for Photodynamic-Photothermal Synergistic Tumor Treatment.
Topics: Adenine; Animals; Base Pairing; Cell Line, Tumor; Combined Modality Therapy; Delayed-Action Preparat | 2019 |
Risk factors for the development of atrial fibrillation on ibrutinib treatment.
Topics: Adenine; Aged; Atrial Fibrillation; Comorbidity; Electrocardiography; Female; Heart Failure; Humans; | 2019 |
Three targets in 1 shot against ibrutinib resistance.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Humans; Neoplasms; Piperidines; Pyrazoles; Pyrimidines | 2019 |
Incidence of opportunistic infections during ibrutinib treatment for B-cell malignancies.
Topics: Adenine; Adult; Aged; Aged, 80 and over; B-Lymphocytes; Female; Humans; Incidence; Male; Middle Aged | 2019 |
Targeted delivery of ibrutinib to tumor-associated macrophages by sialic acid-stearic acid conjugate modified nanocomplexes for cancer immunotherapy.
Topics: Adenine; Animals; Drug Delivery Systems; Immunotherapy; Macrophages; Male; Mice; N-Acetylneuraminic | 2019 |
[Dose reassessment: An answer to the high cost of drugs used in oncology?]
Topics: Abiraterone Acetate; Adenine; Antineoplastic Agents; Clinical Protocols; Dasatinib; Drug Costs; Fran | 2019 |
Ibrutinib related bleeding complications in elderly patients with B cell malignancies.
Topics: Adenine; Aged; B-Lymphocytes; Hemorrhage; Humans; Neoplasms; Piperidines; Pyrazoles; Pyrimidines | 2019 |
Intracellular Trafficking Network and Autophagy of PHBHHx Nanoparticles and their Implications for Drug Delivery.
Topics: Adenine; Animals; Antineoplastic Agents, Phytogenic; Autophagy; Caveolins; Clathrin; Drug Carriers; | 2019 |
Cytotoxic and Antitumor Activity of Lactaptin in Combination with Autophagy Inducers and Inhibitors.
Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Caseins; Cathepsin D; Cell Death; Cel | 2019 |
Stressing the development of small molecules targeting HSP90.
Topics: Adenine; Antineoplastic Agents; Humans; Neoplasms; Pyridines | 2014 |
Dendropanoxide induces autophagy through ERK1/2 activation in MG-63 human osteosarcoma cells and autophagy inhibition enhances dendropanoxide-induced apoptosis.
Topics: Adenine; Apoptosis; Autophagy; Bone Neoplasms; Cell Survival; Enzyme Activation; Humans; MAP Kinase | 2013 |
A novel systemically administered Toll-like receptor 7 agonist potentiates the effect of ionizing radiation in murine solid tumor models.
Topics: Adenine; Animals; B-Lymphocytes; Disease Models, Animal; Female; HEK293 Cells; Humans; Immunotherapy | 2014 |
Raman spectroscopic evaluation of DNA adducts of a platinum containing anticancer drug.
Topics: Adenine; Animals; Antineoplastic Agents; Carboplatin; Cattle; Cisplatin; Cross-Linking Reagents; DNA | 2014 |
PAPD5-mediated 3' adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease.
Topics: Adenine; Base Sequence; Cytosine; Exoribonucleases; Gene Expression Profiling; Gene Expression Regul | 2014 |
Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide.
Topics: Adenine; Base Pairing; Catalytic Domain; Crystallography, X-Ray; Cytosine; Cytotoxins; Deoxyguanine | 2015 |
Inhibition of Hedgehog signaling pathway impedes cancer cell proliferation by promotion of autophagy.
Topics: Adenine; Autophagy; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Hedgehog Proteins; Humans | 2015 |
Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Antiviral Agents; Cell L | 2015 |
Adnectin-targeted inhibitors: rationale and results.
Topics: Adenine; Angiogenesis Inhibitors; Antineoplastic Agents; Bortezomib; Clinical Trials as Topic; Drug | 2015 |
Daucosterol inhibits cancer cell proliferation by inducing autophagy through reactive oxygen species-dependent manner.
Topics: Acetylcysteine; Adenine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cel | 2015 |
Tight binding enantiomers of pre-clinical drug candidates.
Topics: Adenine; Drug Discovery; Escherichia coli; Humans; Models, Molecular; Neoplasms; Plasmodium falcipar | 2015 |
Five cancer drugs back on NHS list after deals with drug companies.
Topics: Adenine; Aniline Compounds; Antineoplastic Agents; Bevacizumab; Brentuximab Vedotin; Cost-Benefit An | 2015 |
Pragmatic randomized clinical trials: a proposal to enhance evaluation of new cancer therapies with early signs of exceptional activity.
Topics: Adenine; Antineoplastic Agents; Drug Evaluation; Humans; Neoplasms; Patient Selection; Piperazines; | 2016 |
Systematic Analysis of AU-Rich Element Expression in Cancer Reveals Common Functional Clusters Regulated by Key RNA-Binding Proteins.
Topics: Adenine; Cell Cycle Checkpoints; Cell Line, Tumor; ELAV-Like Protein 1; Gene Expression Regulation, | 2016 |
The decreased N
Topics: 3T3-L1 Cells; 5-Methylcytosine; Adenine; Animals; Chromatography, High Pressure Liquid; DNA; Gene Ex | 2016 |
The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity.
Topics: Adenine; Cell Line, Tumor; DNA; DNA Methylation; Enhancer Elements, Genetic; Epigenesis, Genetic; Ge | 2016 |
Synthesis and evaluation of novel amonafide-polyamine conjugates as anticancer agents.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug S | 2017 |
The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; ATP Binding Cassette T | 2017 |
Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin, induces autophagy in human cancer cells in a catalase-regulated manner.
Topics: Adenine; Amitrole; Apoptosis; Autophagy; Autophagy-Related Protein 5; Capsaicin; Caspase 3; Catalase | 2008 |
Induction of autophagic cell death by a novel molecule is increased by hypoxia.
Topics: Adenine; Amidines; Androstadienes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic | 2008 |
Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy.
Topics: Adenine; Cell Death; Cell Line; Coculture Techniques; Deoxyadenosines; Drug Screening Assays, Antitu | 2009 |
Nitro-chloromethylbenzindolines: hypoxia-activated prodrugs of potent adenine N3 DNA minor groove alkylators.
Topics: Adenine; Alkylating Agents; Alkylation; Animals; Antineoplastic Agents; Bystander Effect; Cell Cultu | 2009 |
Role of hypoxia and autophagy in MDA-MB-231 invasiveness.
Topics: Adenine; Autophagy; Cell Hypoxia; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Cell Survi | 2010 |
Cancer-derived mutations in the regulatory subunit p85alpha of phosphoinositide 3-kinase function through the catalytic subunit p110alpha.
Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Catalytic Domain; Cell Line | 2010 |
Substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as multi-targeted inhibitors of insulin-like growth factor-1 receptor (IGF1R) and members of ErbB-family receptor kinases.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Human | 2010 |
Computational studies on effects of MDMA as an anticancer drug on DNA.
Topics: Adenine; Antineoplastic Agents; Base Pairing; Cytosine; DNA; Drug Design; Guanine; Humans; Intercala | 2010 |
Quantum-chemical study of interactions of trans-resveratrol with guanine-thymine dinucleotide and DNA-nucleobases.
Topics: Adenine; Antineoplastic Agents, Phytogenic; Cytosine; DNA; DNA Breaks; Guanine; Humans; Hydrogen Bon | 2011 |
Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy.
Topics: Adenine; Autophagy; Cell Death; Cell Survival; Humans; Neoplasms; Radiation Tolerance; Tumor Cells, | 2011 |
Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; HCT116 Cells; Humans; Mice; Mice, Nude; M | 2011 |
Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in HeLa cells.
Topics: Adenine; Androstadienes; Animals; Caspase 3; Cell Cycle Checkpoints; Cell Death; Cell Line; Cell Sur | 2012 |
Tenofovir, COX inhibitors and zileuton during cancer immunotherapies: up-regulated TNF-alpha increases antigen driven lymphocyte proliferation.
Topics: Adenine; Adenylyl Cyclases; Anti-HIV Agents; Cell Division; Cyclooxygenase Inhibitors; Humans; Hydro | 2003 |
The liver nucleic acid incorporation of adenine-8-C14 during azo dye carcinogenesis.
Topics: Adenine; Azo Compounds; Carcinogenesis; Liver; Neoplasms; Nucleic Acids; Organic Chemicals | 1952 |
The effects of tumor growth, x-radiation, and 8-azaguanine on the incorporation of adenine into nucleic acids of mice.
Topics: Adenine; Animals; Azaguanine; Guanine; Mice; Neoplasms; Nucleic Acids; Sarcoma; X-Rays | 1954 |
Glycine and adenine as precursors of nucleic acid purines in tumor-bearing mice.
Topics: Adenine; Animals; Glycine; Mice; Neoplasms; Nucleic Acids; Purines | 1955 |
The effect of tumor fractions on the uptake of carbon-14-labeled adenine into the deoxyribonucleic acids of mouse tissues.
Topics: Adenine; Animals; Carbon Radioisotopes; DNA; Mice; Neoplasms; Nucleic Acids | 1955 |
Stimulation of adenine uptake into mouse lung and liver in vitro by tumor extracts.
Topics: Adenine; Biochemical Phenomena; In Vitro Techniques; Liver; Lung; Neoplasms; Nucleic Acids | 1955 |
[Effect of ribonuclease on the incorporation of adenine and phenylalanine in ascites cells in vitro].
Topics: Adenine; Ascites; Biochemical Phenomena; DNA; Endonucleases; In Vitro Techniques; Neoplasms; Phenyla | 1956 |
Autoradiograph studies with mouse Ehrlich ascites tumor.
Topics: Adenine; Animals; Autoradiography; Biochemical Phenomena; Carcinoma, Ehrlich Tumor; Mice; Neoplasms; | 1956 |
The effect of two purine analogs on a human tumor in tissue culture.
Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop | 1956 |
The effect of two purine analogs on a human tumor in tissue culture.
Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop | 1956 |
The effect of two purine analogs on a human tumor in tissue culture.
Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop | 1956 |
The effect of two purine analogs on a human tumor in tissue culture.
Topics: Adenine; Animals; Antimetabolites; Carcinoma; Carcinoma, Squamous Cell; Humans; Mercaptopurine; Neop | 1956 |
Induced changes in the nucleic acid and nucleotide content of various mouse tissues.
Topics: Adenine; Animals; Antineoplastic Agents; Folic Acid Antagonists; Mice; Neoplasms; Nucleic Acids; Nuc | 1957 |
Studies of the mechanism of action of urethane in initiating pulmonary adenomas in mice. II. Its relation to nucleic acid synthesis.
Topics: Adenine; Adenoma; Animals; DNA; Lung Neoplasms; Mice; Neoplasms; Nucleic Acids; Orotic Acid; Pyrimid | 1957 |
[Cortisone and adenine as protective drugs for leukocytes in deacetyl-colchicine cytostatic therapy].
Topics: Adenine; Colchicine; Cortisone; Humans; Leukocytes; Neoplasms; Protective Agents | 1957 |
Early utilization of adenine and formate by mouse ascites tumor cells in vivo.
Topics: Adenine; Animals; Ascites; Biochemical Phenomena; Diploidy; Formates; Mice; Neoplasms | 1958 |
Effects of 4-aminopyrazolo (3,4-d)pyrimidine and 1-methyl-4-aminopyrazolo(3,4-d)pyrimidine on nucleic acid purine metabolism in ascites tumors.
Topics: Adenine; Ascites; Neoplasms; Nucleic Acids; Purines; Pyrimidines | 1961 |
The metabolism of 4-aminopyrazolo(3,4-d)pyrimidine in normal and neoplastic tissues.
Topics: Adenine; Neoplasms; Pyrimidines | 1961 |
Adenine nucleotide breakdown and its relationship to polynucleotide phosphorylase in the crown-gall tumor inducing organism Agrobacterium tumefaciens.
Topics: Adenine; Adenine Nucleotides; Agrobacterium; Agrobacterium tumefaciens; Crowns; Neoplasms; Nucleotid | 1961 |
[On the determination of the vitality of organ and tumor cultures by incorporation of marked adenine].
Topics: Adenine; Animals; Neoplasms; Neoplasms, Experimental; Tissue Culture Techniques | 1961 |
Permeability of Ehrlich ascites cells to adenine.
Topics: Adenine; Ascites; Biochemical Phenomena; Neoplasms; Permeability; Tissue Culture Techniques | 1960 |
STUDIES OF COMPOUNDS THAT INHIBIT CELL GROWTH.
Topics: Acridines; Adenine; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Guanine; Liver | 1963 |
PHYSIOLOGICAL DISPOSITION AND THERAPEUTIC CONSEQUENCES OF ADENINE ADMINISTERED VIA THE GASTROINTESTINAL TRACT IN NORMAL AND TUMOR-BEARING MICE.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatoc | 1963 |
RNA AND DNA METABOLISM IN LIVER CELLS OF NORMAL AND CANCER-BEARING MICE.
Topics: Adenine; Animals; Autoradiography; DNA; Hepatocytes; Liver; Mammary Neoplasms, Animal; Mammary Neopl | 1963 |
FRACTIONS WITH DIFFERING BASE COMPOSITION IN RNA FROM MALIGNANT CELLS OF MOUSE.
Topics: Adenine; Animals; Autoradiography; Base Composition; Cytosine; Electrophoresis; Guanine; Mice; Neopl | 1963 |
THE CHEMOTHERAPY OF CANCER WITH MASSIVE DOSES UNDER THE PROTECTION OF PERFUSION OF AUTOGENOUS HEMATOPOIETIC TISSUE.
Topics: Adenine; Bone Marrow Transplantation; Breast Neoplasms; DNA; Female; Folic Acid; Humans; Lung Neopla | 1964 |
CONCENTRATIONS AND RATES OF SYNTHESIS OF NICOTINAMIDE-ADENINE-DINUCLEODIDE PHOSPHATE IN PRECANCEROUS LIVERS AND HEPATOMAS INDUCED BY AZO-DYE FEEDING.
Topics: Adenine; Carcinogens; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; NADP; Neoplasms; Neoplasms, | 1964 |
[INCORPORATION OF FORMATE-C14 IN THE BASES OF THE NUCLEIC ACIDS OF STICKER'S TUMOR IN VIVO AND IN VITRO].
Topics: Adenine; Aspartic Acid; Carbon Isotopes; DNA; DNA, Neoplasm; Dogs; Formates; Glucose; Glutamine; In | 1963 |
INHIBITION OF DNA SYNTHESIS IN MAMMALIAN CELLS BY ACTIDIONE.
Topics: Adenine; Adenine Nucleotides; Anti-Bacterial Agents; Aspartic Acid; Carbon Isotopes; Carcinoma, Squa | 1964 |
RADIOAUTOGRAPHIC EVALUATION OF FREEZE-THAW BUFFERS USING NUCLEIC ACID- AND GLYCINE-RELATED SYNTHETIC SYSTEMS IN VITRO.
Topics: Adenine; Autoradiography; Buffers; Dextrans; Dimethyl Sulfoxide; Glycerol; Glycine; In Vitro Techniq | 1964 |
TERATOGENESIS: EFFECTS OF SUBSTITUTED PURINES AND THE INFLUENCE OF 4-HYDROXYPYRAZOLOPYRIMIDINE IN THE RAT.
Topics: Abnormalities, Drug-Induced; Adenine; Female; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Ph | 1964 |
METABOLISM OF PURINE NUCLEOSIDE ANALOGS.
Topics: Adenine; Animals; Antimetabolites; Guanine; Mercaptopurine; Metabolism; Mice; Neoplasms; Neoplasms, | 1965 |
SPECIFICITY OF DNA FROM NEOPLASTIC TISSUES IN VIVO AND IN VITRO.
Topics: Adenine; Animals; Carbon Isotopes; Cytosine; DNA; DNA, Neoplasm; Formates; Guanine; Histocytochemist | 1964 |
ON THE OXIDATIVE PHOSPHORYLATION AND NUCLEIC ACIDS METABOLISM IN SOME ORGANS OF ANIMALS WITH TRANSPLANTABLE TUMOURS.
Topics: Adenine; Carbohydrate Metabolism; Cytosine; DNA; DNA, Neoplasm; Glycolysis; Guanine; Intestines; Kid | 1964 |
THE EFFECTS OF 3'-DEOXYADENOSINE ON THE SYNTHESIS OF RIBONUCLEIC ACID.
Topics: Adenine; Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents; Carbon Isotopes; Carcinoma, | 1965 |
METABOLIC EFFECTS OF AN ANTIBIOTIC, NSC-51954, ON SUSCEPTIBLE AND RESISTANT TUMOR CELLS.
Topics: Adenine; Animals; Anti-Bacterial Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA; DNA, Neopla | 1965 |
THE EFFECT OF BETA-XYLOSYL ADENINE ON THE FORMATION OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE BY CELL-FREE EXTRACTS OF TA3 ASCITES CELLS.
Topics: Adenine; Adenosine Triphosphate; Animals; Antimetabolites; Ascites; Carbon Isotopes; Diphosphates; M | 1965 |
BASE COMPOSITION OF HIGH MOLECULAR WEIGHT NUCLEAR RNA OF WALKER TUMOR AND LIVER OF THE RAT.
Topics: Adenine; Adenine Nucleotides; Animals; Base Composition; Carcinoma 256, Walker; Cytosine; Cytosine N | 1965 |
Stimulation of tumorous aggregations in Drosophila by addition of indoleacetic acid and adenine to culture medium.
Topics: Adenine; Animals; Culture Media; Drosophila; Indoleacetic Acids; Neoplasms; Neoplasms, Experimental | 1955 |
On the effect of some adenine derivatives on the incorporation in vitro of isotopically labelled compounds into the nucleic acids of Ehrlich ascites tumor cells.
Topics: Adenine; Animals; Biochemical Phenomena; Carcinoma, Ehrlich Tumor; Formates; In Vitro Techniques; Ne | 1959 |
Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.
Topics: Adenine; Animals; Anisoles; Antineoplastic Agents; Cell Division; Cell Line; Cell Line, Tumor; Cell | 2004 |
Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; | 2004 |
The reductive cleavage of 4-dimethylaminoazobenzene by rat liver: reactivation of carbon dioxide-treated homogenates by riboflavin-adenine dinucleotide.
Topics: Adenine; Azo Compounds; Carbon Dioxide; Flavin-Adenine Dinucleotide; Liver; Neoplasms; p-Dimethylami | 1950 |
DNA minor groove adducts formed by a platinum-acridine conjugate inhibit association of tata-binding protein with its cognate sequence.
Topics: Acridines; Adenine; Animals; Antineoplastic Agents; Binding Sites; DNA Adducts; Humans; Neoplasms; N | 2005 |
Synthesis and biological activity of 2-fluoro adenine and 6-methyl purine nucleoside analogs as prodrugs for suicide gene therapy of cancer.
Topics: Adenine; Antineoplastic Agents; Carbon; Escherichia coli; Genetic Therapy; Humans; Models, Chemical; | 2005 |
Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
Topics: Adenine; Adenosine Triphosphate; Bone and Bones; Carbon; Catalytic Domain; Cyclin-Dependent Kinase 2 | 2006 |
Antitumor activity of sequence-specific alkylating agents: pyrolle-imidazole CBI conjugates with indole linker.
Topics: Adenine; Alkylation; Animals; Antineoplastic Agents, Alkylating; Base Sequence; Cell Line, Tumor; Cy | 2006 |
Formation of depurinating N3adenine and N7guanine adducts after reaction of 1,2-naphthoquinone or enzyme-activated 1,2-dihydroxynaphthalene with DNA. Implications for the mechanism of tumor initiation by naphthalene.
Topics: Adenine; Carcinogens; DNA Adducts; Guanine; Kinetics; Molecular Structure; Naphthalenes; Naphthols; | 2007 |
A cis and trans adenine-dependent hairpin ribozyme against Tpl-2 target.
Topics: Adenine; Animals; Base Sequence; Catalysis; Humans; Hydrogen-Ion Concentration; Magnesium; MAP Kinas | 2007 |
The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; H | 2007 |
Evidence of complete cellular repair of 1,N6-ethenoadenine, a mutagenic and potential damage for human cancer, revealed by a novel method.
Topics: Adenine; Animals; Biological Assay; Cell Cycle; Cell Extracts; DNA; DNA Damage; DNA Repair; HCT116 C | 2008 |
Transport of folate compounds, pterins and adenine in L1210 mouse leukemia cells.
Topics: Adenine; Animals; Biological Transport; Energy Metabolism; Folic Acid; Leukemia L1210; Membranes; Me | 1982 |
ATM mutations in cancer families.
Topics: Adenine; Alleles; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; C | 1996 |
Mechanistic study on the cytostatic and tumor cell differentiation-inducing properties of 9-(2-phosphonylmethoxyethyl)adenine (PMEA, adefovir)-collected publications.
Topics: Adenine; Animals; Antineoplastic Agents; Antiviral Agents; Cell Differentiation; Cell Division; Cell | 2000 |
Preclinical antitumor activity of the azonafide series of anthracene-based DNA intercalators.
Topics: Adenine; Animals; Antineoplastic Agents; Colony-Forming Units Assay; Dose-Response Relationship, Dru | 2001 |
Cancer procoagulant and blood platelet activation.
Topics: Adenine; Animals; Blood Platelets; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Neopla | 2001 |
Storage of unprocessed G-CSF-mobilized whole blood in a modified Leibovitz's L15 medium preserves clonogenic capacity for at least 7 days.
Topics: Adenine; Antigens, CD; Antigens, CD34; Blood Preservation; Breast Neoplasms; Cell Culture Techniques | 2001 |
Determination of trimethylsilyl methylated nucleic acid bases in urine by gas-liquid chromatography.
Topics: Adenine; Adsorption; Chromatography, Gas; Guanine; Humans; Hydrogen-Ion Concentration; Hydrolysis; M | 1976 |
High-resolution liquid chromatographic analysis of methylated purine and pyrimidine bases in transfer RNA.
Topics: Adenine; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Liquid; Cytosine; Guanine; | 1976 |
[Analysis of normal and methylated urinary nucleobases: a new criterion for diagnosis and follow-up of malignancies (author's transl)].
Topics: Adenine; Adolescent; Adult; Child; Child, Preschool; Creatinine; Guanine; Humans; Infant; Neoplasms; | 1979 |
New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors.
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; In Vitro Techniques; Leu | 1975 |
Disturbance in the metabolism of 5'-methylthioadenosine and adenine in patients with neoplastic diseases, and in those with a deficiency in adenine phosphoribosyltransferase.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adult; Aged; Deoxyadenosines; Female; Humans; | 1991 |
Flexibility of nucleic acid bases and its possible relationship with carcinogenesis.
Topics: Adenine; Animals; Cytosine; DNA; Guanine; Humans; Hydrogen Bonding; Neoplasms; Nucleic Acid Conforma | 1985 |
Studies on the mechanism of cytotoxicity of 3-deazaguanosine in human cancer cells.
Topics: Adenine; Cell Division; Cells, Cultured; DNA; Formates; GMP Reductase; Guanine; Guanosine; Humans; N | 1985 |
[The genetic effect of aromatic amines and their derivatives: induction of mytotic conversion in the yeast Saccharomyces cerevisiae].
Topics: Adenine; Amines; Carcinogens; Chemical Phenomena; Chemistry; Culture Media; Fluorenes; Genes; Geneti | 1970 |
Purine N-oxides. XIX. On the oncogenic N-oxide derivatives of guanine and xanthine and a nononcogenic isomer of xanthine N-oxide.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Guanine; Liver Neoplasms; Mercaptopurine; Neoplasms; Ne | 1967 |
Inhibitors of nucleoside and nucleotide metabolism.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Erythrocytes; Guan | 1972 |
Drugs used in radiotherapy.
Topics: Adenine; Alkylating Agents; Analgesics; Anemia; Anti-Bacterial Agents; Antiemetics; Antimetabolites; | 1972 |
7-methylguanine and other minor urinary purines: values for normal subjects from Israel, Gaza, and Kenya, and for patients with cancer of various organs or cirrhosis of the liver.
Topics: Adenine; Adult; Aged; Arabia; Child; Creatinine; Female; Humans; Hypoxanthines; Israel; Kenya; Liver | 1971 |
Some aspects of the role of vitamin B 12 and folic acid in DNA-thymidine sy nthesis in a neoplastic C3H mouse cell strain.
Topics: Adenine; Animals; Carbon Isotopes; Cell Line; Chromatography, Paper; Culture Media; Culture Techniqu | 1971 |
Effects of nitrogen mustard and cyclophosphamide upon the synthesis of DNA in vivo and in cell-free preparations.
Topics: Adenine; Animals; Carbon Isotopes; Cell-Free System; Cricetinae; Cyclophosphamide; Depression, Chemi | 1969 |