adenine has been researched along with Muscle Relaxation in 26 studies
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of the present study was to ascertain the role of adenylate (AC) versus guanylate cyclase (GC) signaling pathways in the internal anal sphincter (IAS) smooth muscle relaxation by beta(1)-, beta(2)-, and beta(3)-adrenoceptor (AR) activation by xamoterol, procaterol, and disodium 5-[(2R)-2-(3-chlorophenyl)-2-hydroxy-ethyl]amino)propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316243), respectively." | 3.72 | Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle. ( De Godoy, M; Li, F; Rattan, S, 2004) |
| " The Beraprost- and PGI2-induced muscle relaxations were significantly inhibited by each of the PG antagonist diphloretin phosphate, the adenylate cyclase inhibitor SQ 22,536, and the Na(+)-K(+)-ATPase inhibitor ouabain." | 3.68 | Relaxation and inhibition of contractile response to electrical field stimulation by Beraprost sodium in canine airway smooth muscle. ( Chiyotani, A; Konno, K; Tagaya, E; Takeyama, K; Tamaoki, J; Yamauchi, F, 1993) |
| "Rats with adenine-induced chronic renal failure (A-CRF) develop a reduced rate of relaxation of the thoracic aorta." | 1.43 | Adenine-induced chronic renal failure in rats decreases aortic relaxation rate and alters expression of proteins involved in vascular smooth muscle calcium handling. ( Guron, G; Jernås, M; Lundgren, J; Nguy, L; Nilsson, H; Nookaew, I; Olsson, B; Shubbar, E, 2016) |
| "Rats with adenine-induced chronic renal failure (A-CRF) develop metabolic and cardiovascular abnormalities resembling those in patients with chronic kidney disease." | 1.39 | Rats with adenine-induced chronic renal failure develop low-renin, salt-sensitive hypertension and increased aortic stiffness. ( Carlström, M; Grimberg, E; Guron, G; Johansson, ME; Lundberg, JO; Lundgren, J; Nguy, L; Nilsson, H; Teerlink, T, 2013) |
| " ODQ (1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one), a potent and selective inhibitor of soluble guanylyl cyclase (sGC), did not significantly affect relaxant actions of ONOO-, but ODQ markedly attenuated SIN-1-elicited relaxation with a rightward shift in the dose-response curve and an unaltered maximal response." | 1.31 | Comparative vasodilation of peroxynitrite and 3-morpholinosydnonimine. ( Trakranrungsie, N; Will, JA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (15.38) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 11 (42.31) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Matsumoto, T | 1 |
| Takayanagi, K | 1 |
| Katome, T | 1 |
| Kojima, M | 1 |
| Taguchi, K | 1 |
| Kobayashi, T | 1 |
| Nguy, L | 2 |
| Johansson, ME | 1 |
| Grimberg, E | 1 |
| Lundgren, J | 2 |
| Teerlink, T | 1 |
| Carlström, M | 1 |
| Lundberg, JO | 1 |
| Nilsson, H | 2 |
| Guron, G | 2 |
| Shubbar, E | 1 |
| Jernås, M | 1 |
| Nookaew, I | 1 |
| Olsson, B | 1 |
| Dhaese, I | 1 |
| Lefebvre, RA | 3 |
| Yamazaki, T | 1 |
| Anraku, T | 1 |
| Matsuzawa, S | 1 |
| Sutliff, RL | 1 |
| Walp, ER | 1 |
| El-Ali, AM | 1 |
| Elkhatib, S | 1 |
| Lomashvili, KA | 1 |
| O'Neill, WC | 1 |
| Montaño, LM | 1 |
| Cruz-Valderrama, JE | 1 |
| Figueroa, A | 1 |
| Flores-Soto, E | 1 |
| García-Hernández, LM | 1 |
| Carbajal, V | 1 |
| Segura, P | 1 |
| Méndez, C | 1 |
| Díaz, V | 1 |
| Barajas-López, C | 1 |
| Nishio, A | 1 |
| Kitamura, N | 1 |
| Tanaka, S | 1 |
| Miyazaki, S | 1 |
| Ichiyanagi, T | 1 |
| Shimomura, N | 1 |
| Shibuya, I | 1 |
| Aimi, T | 1 |
| Li, F | 1 |
| De Godoy, M | 1 |
| Rattan, S | 2 |
| de Godoy, MA | 1 |
| de Oliveira, AM | 1 |
| Frazier, EP | 1 |
| Mathy, MJ | 1 |
| Peters, SL | 1 |
| Michel, MC | 1 |
| Uchida, H | 1 |
| Shishido, K | 1 |
| Nomiya, M | 1 |
| Yamaguchi, O | 1 |
| Karlsson, JA | 1 |
| Persson, CG | 1 |
| Tamaoki, J | 1 |
| Chiyotani, A | 1 |
| Takeyama, K | 1 |
| Yamauchi, F | 1 |
| Tagaya, E | 1 |
| Konno, K | 1 |
| Martin, PL | 2 |
| Potts, AA | 1 |
| Sykes, AM | 1 |
| McKenna, DG | 1 |
| Ueeda, M | 1 |
| Olsson, RA | 1 |
| Filippi, S | 1 |
| Amerini, S | 1 |
| Maggi, M | 1 |
| Natali, A | 1 |
| Ledda, F | 1 |
| Dick, JM | 2 |
| Van Geldre, LA | 1 |
| Timmermans, JP | 1 |
| Triguero, D | 1 |
| Costa, G | 1 |
| Labadía, A | 1 |
| Jiménez, E | 1 |
| García-Pascual, A | 1 |
| Trakranrungsie, N | 1 |
| Will, JA | 1 |
| Jones, OM | 1 |
| Brading, AF | 1 |
| McC Mortensen, NJ | 1 |
| Horinouchi, T | 1 |
| Koike, K | 1 |
| Fathi-Afshar, R | 1 |
| Allen, TM | 1 |
| Krueger, CA | 1 |
| Cook, DA | 1 |
| Clanachan, AS | 1 |
| Vriend, R | 1 |
| Baer, HP | 1 |
| Cass, CE | 1 |
| Nakagawa, Y | 1 |
| Gudenzi, M | 1 |
| Mustafa, SJ | 1 |
| Krzanowski, JJ | 1 |
| Urdaneta-Bohorquez, A | 1 |
| Polson, JB | 1 |
| Sakamoto, Y | 1 |
| Szentivanyi, A | 1 |
26 other studies available for adenine and Muscle Relaxation
| Article | Year |
|---|---|
Reduced Relaxant Response to Adenine in the Superior Mesenteric Artery of Spontaneously Hypertensive Rats.
Topics: Adenine; Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertensio | 2021 |
Rats with adenine-induced chronic renal failure develop low-renin, salt-sensitive hypertension and increased aortic stiffness.
Topics: Adenine; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Arterial Pressure; Benzimidazoles; | 2013 |
Adenine-induced chronic renal failure in rats decreases aortic relaxation rate and alters expression of proteins involved in vascular smooth muscle calcium handling.
Topics: Adenine; Animals; Aorta, Thoracic; Blotting, Western; Calcium; Disease Models, Animal; Kidney Failur | 2016 |
Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus.
Topics: Adenine; Amides; Animals; Enzyme Activation; Gastric Fundus; Glyburide; Hydrogen Sulfide; In Vitro T | 2009 |
Ibudilast, a mixed PDE3/4 inhibitor, causes a selective and nitric oxide/cGMP-independent relaxation of the intracranial vertebrobasilar artery.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Animals; Basilar Artery; Cyclic GMP; Guanylate Cyclase; In Vit | 2011 |
Effect of medial calcification on vascular function in uremia.
Topics: Acetylcholine; Adenine; Animals; Aorta, Thoracic; Calcinosis; Calcium; Compliance; Dietary Proteins; | 2011 |
Characterization of P2Y receptors mediating ATP induced relaxation in guinea pig airway smooth muscle: involvement of prostaglandins and K+ channels.
Topics: 4-Aminopyridine; Adenine; Adenosine Triphosphate; Animals; Ethylmaleimide; Guinea Pigs; Male; Muscle | 2011 |
Multiple effects of gymnopilin on circulatory system of the rat.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Angiotensin II; Animals; Aorta, Thoracic; Basidiomycota; Biolo | 2012 |
Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle.
Topics: Adenine; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blotting | 2004 |
Angiotensin II-induced relaxation of anococcygeus smooth muscle via desensitization of AT1 receptor, and activation of AT2 receptor associated with nitric-oxide synthase pathway.
Topics: Adenine; Angiotensin II; Animals; Blotting, Western; CD13 Antigens; Drug Interactions; Glutamyl Amin | 2004 |
Does cyclic AMP mediate rat urinary bladder relaxation by isoproterenol?
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine; Adenylyl Cyclase Inhibitors; Adrenergic beta | 2005 |
Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via beta-adrenoceptors.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adrenergic beta-Agonists; Animals; Benzocycloheptenes; Clenbut | 2005 |
Neither vasoactive intestinal peptide (VIP) nor purine derivatives may mediate non-adrenergic tracheal inhibition.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Atropine; Carbachol; Electric Stimulation; Fema | 1984 |
Relaxation and inhibition of contractile response to electrical field stimulation by Beraprost sodium in canine airway smooth muscle.
Topics: Acetylcholine; Adenine; Adenylyl Cyclase Inhibitors; Animals; Bronchi; Dogs; Electric Stimulation; E | 1993 |
(+-)-N6-endonorbornan-2-yl-9-methyladenine (N-0861) and its enantiomers: selective antagonists of A1-adenosine receptors in guinea pig isolated atria.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Drug Antagonism; Guinea Pigs; | 1993 |
2-Phenylethoxy-9-methyladenine: an adenosine receptor antagonist that discriminates between A2 adenosine receptors in the aorta and the coronary vessels from the guinea pig.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Coronary Vessels; Guinea Pigs | 1993 |
Studies on the mechanisms involved in the ATP-induced relaxation in human and rabbit corpus cavernosum.
Topics: Adenine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Humans; Male | 1999 |
Investigation of the interaction between nitric oxide and vasoactive intestinal polypeptide in the guinea-pig gastric fundus.
Topics: Adenine; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Carbachol; Colforsin; Cyclic | 2000 |
Spontaneous photo-relaxation of urethral smooth muscle from sheep, pig and rat and its relationship with nitrergic neurotransmission.
Topics: Adenine; Animals; Citrulline; Cold Temperature; Culture Techniques; Electric Stimulation; Enzyme Inh | 2000 |
Interplay between nitric oxide and vasoactive intestinal polypeptide in the pig gastric fundus smooth muscle.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Amidines; Animals; Arginine; Benzylamines; Carbazoles; Colfors | 2000 |
Comparative vasodilation of peroxynitrite and 3-morpholinosydnonimine.
Topics: Adenine; Animals; Benzoates; Cattle; Dose-Response Relationship, Drug; Drug Combinations; Drug Inter | 2001 |
Phosphodiesterase inhibitors cause relaxation of the internal anal sphincter in vitro.
Topics: Adenine; Aged; Aged, 80 and over; Anal Canal; Dipyridamole; Dose-Response Relationship, Drug; Female | 2002 |
Cyclic AMP-independent relaxation mediated by beta3-adrenoceptors on guinea pig gastrointestine.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals | 2002 |
Some pharmacological activities of novel adenine-related compounds isolated from a marine sponge Agelas mauritiana.
Topics: Adenine; Adenosine; Animals; Aorta; Cell Cycle; Erythrocytes; In Vitro Techniques; Kinetics; Leukemi | 1989 |
Calcium entry blocking activity of dilazep in dog coronary artery.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Arteries; Azepines; Calcium; Calcium Channel Block | 1986 |
Effects of adenosine and theophylline on canine tracheal smooth muscle tone.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Dogs; Drug Interactions; In Vitro Techniques; Inosine; Ma | 1987 |