Page last updated: 2024-10-16

adenine and Medulloblastoma

adenine has been researched along with Medulloblastoma in 5 studies

Medulloblastoma: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)

Research Excerpts

ExcerptRelevanceReference
" Using an in vivo model system, we report a simple and sensitive liquid chromatography-tandem mass spectrometry assay to quantify the bioavailability of a recently developed novel cyclin-dependent kinase inhibitor VMY-1-103, a purvalanol B-based analog whose biological activity is enhanced via dansylation."1.38Quantifying the CDK inhibitor VMY-1-103's activity and tissue levels in an in vivo tumor model by LC-MS/MS and by MRI. ( Albanese, C; Das, S; Fricke, ST; Karam, S; Lee, YC; Lisanti, MP; Moasser, B; Ozcan, A; Petricoin, E; Pishvaian, M; Ringer, L; Rodriguez, OC; Rood, B; Salinas, P; Schlegel, R; Sirajuddin, P; Sivakumar, A; Üren, A; Wang, SS; Wang, Y; Yenugonda, V, 2012)
"Medulloblastoma is the most prevalent of childhood brain malignancies, constituting 25% of childhood brain tumors."1.37VMY-1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells. ( Albanese, C; Brown, ML; Ghosh, A; Glazer, RI; Heckler, M; Lee, Y; MacDonald, TJ; Ringer, L; Rodriguez, O; Schlegel, R; Sirajuddin, P; Suprynowicz, F; Toretsky, JA; Uren, A; Yenugonda, VM, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jamison, S1
Lin, Y1
Lin, W1
Morfouace, M1
Cheepala, S1
Jackson, S1
Fukuda, Y1
Patel, YT1
Fatima, S1
Kawauchi, D1
Shelat, AA1
Stewart, CF1
Sorrentino, BP1
Schuetz, JD1
Roussel, MF1
Waye, S1
Naeem, A1
Choudhry, MU1
Parasido, E1
Tricoli, L1
Sivakumar, A2
Mikhaiel, JP1
Yenugonda, V2
Rodriguez, OC2
Karam, SD1
Rood, BR1
Avantaggiati, ML1
Albanese, C3
Ringer, L2
Sirajuddin, P2
Heckler, M1
Ghosh, A1
Suprynowicz, F1
Yenugonda, VM1
Brown, ML1
Toretsky, JA1
Uren, A2
Lee, Y1
MacDonald, TJ1
Rodriguez, O1
Glazer, RI1
Schlegel, R2
Das, S1
Lee, YC1
Fricke, ST1
Rood, B1
Ozcan, A1
Wang, SS1
Karam, S1
Salinas, P1
Petricoin, E1
Pishvaian, M1
Lisanti, MP1
Wang, Y1
Moasser, B1

Other Studies

5 other studies available for adenine and Medulloblastoma

ArticleYear
Pancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor A.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Adenine; Cell Line, Tumor; Cell Movement; Cerebellar Neoplasms; eIF-2 Kinase; Endoplasmic Reticulum;

2015
ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy.
    Cancer research, 2015, Sep-15, Volume: 75, Issue:18

    Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, M

2015
The p53 tumor suppressor protein protects against chemotherapeutic stress and apoptosis in human medulloblastoma cells.
    Aging, 2015, Volume: 7, Issue:10

    Topics: Adenine; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Dansyl Compounds; Drug Evaluation, Pre

2015
VMY-1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells.
    Cancer biology & therapy, 2011, Nov-01, Volume: 12, Issue:9

    Topics: Adenine; Antineoplastic Agents; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Centrosome; Cereb

2011
Quantifying the CDK inhibitor VMY-1-103's activity and tissue levels in an in vivo tumor model by LC-MS/MS and by MRI.
    Cell cycle (Georgetown, Tex.), 2012, Oct-15, Volume: 11, Issue:20

    Topics: Adenine; Animals; Antineoplastic Agents; Biological Availability; Cell Cycle; Cerebellar Neoplasms;

2012