adenine has been researched along with Malaria, Falciparum in 4 studies
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adozelesin is a DNA alkylating agent that exhibits specificity for the motif A/T, A/T and A." | 1.33 | The A/T-specific DNA alkylating agent adozelesin inhibits Plasmodium falciparum growth in vitro and protects mice against Plasmodium chabaudi adami infection. ( Purcell, LA; Spithill, TW; Yanow, SK, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurian, J | 1 |
| Kumari, V | 1 |
| Chaluvalappil, SV | 1 |
| Anas, M | 1 |
| Manhas, A | 1 |
| Kalluruttimmal, R | 1 |
| Kumar, N | 1 |
| Manheri, MK | 1 |
| Yanow, SK | 1 |
| Purcell, LA | 1 |
| Spithill, TW | 1 |
| Downie, MJ | 1 |
| Saliba, KJ | 1 |
| Bröer, S | 1 |
| Howitt, SM | 1 |
| Kirk, K | 1 |
| Smeijsters, LJ | 1 |
| Zijlstra, NM | 1 |
| de Vries, E | 1 |
| Franssen, FF | 1 |
| Janse, CJ | 1 |
| Overdulve, JP | 1 |
4 other studies available for adenine and Malaria, Falciparum
| Article | Year |
|---|---|
Adenine Modification at C7 as a Viable Strategy to Potentiate the Antimalarial Activity of Quinolones.
Topics: Adenine; Animals; Antimalarials; Chlorocebus aethiops; Dose-Response Relationship, Drug; Malaria, Fa | 2022 |
The A/T-specific DNA alkylating agent adozelesin inhibits Plasmodium falciparum growth in vitro and protects mice against Plasmodium chabaudi adami infection.
Topics: Adenine; Animals; Antimalarials; Base Pairing; Benzofurans; Cyclohexanecarboxylic Acids; Cyclohexene | 2006 |
Purine nucleobase transport in the intraerythrocytic malaria parasite.
Topics: Adenine; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Erythrocytes; Hypox | 2008 |
The effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl) adenine on nuclear and organellar DNA synthesis in erythrocytic schizogony in malaria.
Topics: Adenine; Animals; Antimalarials; Cell Nucleus; DNA Replication; DNA, Protozoan; Erythrocytes; Humans | 1994 |