Page last updated: 2024-10-16

adenine and Malaria, Falciparum

adenine has been researched along with Malaria, Falciparum in 4 studies

Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.

Research Excerpts

ExcerptRelevanceReference
"Adozelesin is a DNA alkylating agent that exhibits specificity for the motif A/T, A/T and A."1.33The A/T-specific DNA alkylating agent adozelesin inhibits Plasmodium falciparum growth in vitro and protects mice against Plasmodium chabaudi adami infection. ( Purcell, LA; Spithill, TW; Yanow, SK, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Kurian, J1
Kumari, V1
Chaluvalappil, SV1
Anas, M1
Manhas, A1
Kalluruttimmal, R1
Kumar, N1
Manheri, MK1
Yanow, SK1
Purcell, LA1
Spithill, TW1
Downie, MJ1
Saliba, KJ1
Bröer, S1
Howitt, SM1
Kirk, K1
Smeijsters, LJ1
Zijlstra, NM1
de Vries, E1
Franssen, FF1
Janse, CJ1
Overdulve, JP1

Other Studies

4 other studies available for adenine and Malaria, Falciparum

ArticleYear
Adenine Modification at C7 as a Viable Strategy to Potentiate the Antimalarial Activity of Quinolones.
    ChemMedChem, 2022, 01-19, Volume: 17, Issue:2

    Topics: Adenine; Animals; Antimalarials; Chlorocebus aethiops; Dose-Response Relationship, Drug; Malaria, Fa

2022
The A/T-specific DNA alkylating agent adozelesin inhibits Plasmodium falciparum growth in vitro and protects mice against Plasmodium chabaudi adami infection.
    Molecular and biochemical parasitology, 2006, Volume: 148, Issue:1

    Topics: Adenine; Animals; Antimalarials; Base Pairing; Benzofurans; Cyclohexanecarboxylic Acids; Cyclohexene

2006
Purine nucleobase transport in the intraerythrocytic malaria parasite.
    International journal for parasitology, 2008, Volume: 38, Issue:2

    Topics: Adenine; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Erythrocytes; Hypox

2008
The effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl) adenine on nuclear and organellar DNA synthesis in erythrocytic schizogony in malaria.
    Molecular and biochemical parasitology, 1994, Volume: 67, Issue:1

    Topics: Adenine; Animals; Antimalarials; Cell Nucleus; DNA Replication; DNA, Protozoan; Erythrocytes; Humans

1994