adenine has been researched along with MELAS in 10 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This mutation can also cause MELAS syndrome (which encompasses mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke), and other genetic factors may contribute to the clinical expression." | 1.34 | A MELAS-associated ND1 mutation causing leber hereditary optic neuropathy and spastic dystonia. ( Bettink-Remeijer, MW; de Coo, IF; Hendrickx, A; Hintzen, RQ; Maat-Kievit, A; Schoonderwoerd, KC; Sluiter, W; Smeets, HJ; Spruijt, L, 2007) |
| "MELAS is a multisystem disorder inherited by the mitochondrial DNA with onset typically in childhood." | 1.32 | [Phenotypic variants of A3243G mitochondrial DNA mutation in a Hungarian family]. ( Bene, J; Havasi, V; Herczegfalvi, A; Komlósi, K; Melegh, B; Móser, J; Tihanyi, M, 2004) |
| "The patients with MELAS had lower mutation levels as well as a lower proportion of RRF, and these two parameters were even lower in the PEO and MDM patients." | 1.31 | Single-fiber analysis of mitochondrial A3243G mutation in four different phenotypes. ( Akita, Y; Iwanaga, R; Kato, H; Koga, A; Koga, Y; Matsuishi, T; Sato, Y; Takane, N; Tubone, J, 2000) |
| "The majority of patients with MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes) have an A-->G mutation at nucleotide 3243 in mitochondrial transfer (t)RNA." | 1.30 | Clinical, physiological, and histological features in a kindred with the T3271C melas mutation. ( Applegarth, D; Maguire, J; Myint, T; Robinson, BH; Tarnopolsky, MA, 1998) |
| "I analyzed this mutation in a Japanese MELAS pedigree by PCR." | 1.29 | Did de novo MELAS common mitochondrial DNA point mutation (mtDNA 3243, A-->G transition) occur in the mother of a proband of a Japanese MELAS pedigree? ( Yamamoto, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, H | 1 |
| Davidson, E | 1 |
| King, MP | 1 |
| Komlósi, K | 1 |
| Bene, J | 1 |
| Havasi, V | 1 |
| Tihanyi, M | 1 |
| Herczegfalvi, A | 1 |
| Móser, J | 1 |
| Melegh, B | 1 |
| Spruijt, L | 1 |
| Smeets, HJ | 1 |
| Hendrickx, A | 1 |
| Bettink-Remeijer, MW | 1 |
| Maat-Kievit, A | 1 |
| Schoonderwoerd, KC | 1 |
| Sluiter, W | 1 |
| de Coo, IF | 1 |
| Hintzen, RQ | 1 |
| Betts, J | 1 |
| Barron, MJ | 1 |
| Needham, SJ | 1 |
| Schaefer, AM | 1 |
| Taylor, RW | 1 |
| Turnbull, DM | 1 |
| Sakuta, R | 1 |
| Goto, Y | 1 |
| Nonaka, I | 1 |
| Horai, S | 1 |
| Feigenbaum, A | 1 |
| Chitayat, D | 1 |
| Robinson, B | 1 |
| MacGregor, D | 1 |
| Myint, T | 2 |
| Arbus, G | 1 |
| Nowaczyk, MJ | 1 |
| Yamamoto, M | 1 |
| Tarnopolsky, MA | 1 |
| Maguire, J | 1 |
| Applegarth, D | 1 |
| Robinson, BH | 1 |
| Latkany, P | 1 |
| Ciulla, TA | 1 |
| Cacchillo, PF | 1 |
| Malkoff, MD | 1 |
| Koga, Y | 1 |
| Koga, A | 1 |
| Iwanaga, R | 1 |
| Akita, Y | 1 |
| Tubone, J | 1 |
| Matsuishi, T | 1 |
| Takane, N | 1 |
| Sato, Y | 1 |
| Kato, H | 1 |
10 other studies available for adenine and MELAS
| Article | Year |
|---|---|
The pathogenic A3243G mutation in human mitochondrial tRNALeu(UUR) decreases the efficiency of aminoacylation.
Topics: Acylation; Adenine; Base Sequence; Cell Line; Cytosine; Guanine; Humans; Leucine-tRNA Ligase; MELAS | 2003 |
[Phenotypic variants of A3243G mitochondrial DNA mutation in a Hungarian family].
Topics: Adenine; Child; DNA Mutational Analysis; DNA, Mitochondrial; Female; Genetic Variation; Guanine; Hea | 2004 |
A MELAS-associated ND1 mutation causing leber hereditary optic neuropathy and spastic dystonia.
Topics: Adenine; Adult; DNA, Mitochondrial; Dystonia; Female; Guanine; Humans; MELAS Syndrome; Muscle Spasti | 2007 |
Gastrointestinal tract involvement associated with the 3243A>G mitochondrial DNA mutation.
Topics: Adenine; Adult; Base Sequence; DNA Mutational Analysis; DNA, Mitochondrial; Electron Transport Compl | 2008 |
An A-to-G transition at nucleotide pair 11084 in the ND4 gene may be an mtDNA polymorphism.
Topics: Adenine; DNA, Mitochondrial; Guanine; Humans; MELAS Syndrome; Mutation; Polymorphism, Genetic | 1993 |
The expanding clinical phenotype of the tRNA(Leu(UUR)) A-->G mutation at np 3243 of mitochondrial DNA: diabetic embryopathy associated with mitochondrial cytopathy.
Topics: Abnormalities, Multiple; Adenine; Adult; Anus, Imperforate; Base Sequence; DNA, Mitochondrial; Femal | 1996 |
Did de novo MELAS common mitochondrial DNA point mutation (mtDNA 3243, A-->G transition) occur in the mother of a proband of a Japanese MELAS pedigree?
Topics: Adenine; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Base Sequence; Family Health; Female; Gu | 1996 |
Clinical, physiological, and histological features in a kindred with the T3271C melas mutation.
Topics: Adenine; Adult; Biopsy, Needle; Child, Preschool; Cytosine; DNA; DNA, Mitochondrial; Female; Forearm | 1998 |
Mitochondrial maculopathy: geographic atrophy of the macula in the MELAS associated A to G 3243 mitochondrial DNA point mutation.
Topics: Adenine; Atrophy; Deafness; DNA, Mitochondrial; Electroretinography; Female; Guanine; Humans; Macula | 1999 |
Single-fiber analysis of mitochondrial A3243G mutation in four different phenotypes.
Topics: Adenine; Adult; Child; Diabetes Mellitus; DNA, Mitochondrial; Guanine; Humans; Leigh Disease; MELAS | 2000 |